diff --git a/src/Avalonia.Input/MouseDevice.cs b/src/Avalonia.Input/MouseDevice.cs
index 3749947da9e..eed51e6c4a6 100644
--- a/src/Avalonia.Input/MouseDevice.cs
+++ b/src/Avalonia.Input/MouseDevice.cs
@@ -5,6 +5,7 @@
 using Avalonia.Input.Raw;
 using Avalonia.Interactivity;
 using Avalonia.Platform;
+using Avalonia.Utilities;
 using Avalonia.VisualTree;
 
 namespace Avalonia.Input
@@ -334,6 +335,13 @@ private bool MouseWheel(IMouseDevice device, ulong timestamp, IInputRoot root, P
             var hit = HitTest(root, p);
             var source = GetSource(hit);
 
+            // KeyModifiers.Shift should scroll in horizontal direction. This does not work on every platform. 
+            // If Shift-Key is pressed and X is close to 0 we swap the Vector.
+            if (inputModifiers == KeyModifiers.Shift && MathUtilities.IsZero(delta.X))
+            {
+                delta = new Vector(delta.Y, delta.X);
+            }
+
             if (source is not null)
             {
                 var e = new PointerWheelEventArgs(source, _pointer, root, p, timestamp, props, inputModifiers, delta);