For solr cloud, you need to use Configsets API and Collections API to configure a collection.
$ (cd genome && zip -r - *) | \
curl -X POST --header 'Content-Type:application/octet-stream' --data-binary @- \
'http://localhost:8983/solr/admin/configs?action=UPLOAD&name=genome_set'
You can lookup what configsets are available,
curl http://localhost:8983/api/cluster/configs'
or delete
curl -X DELETE 'http://localhost:8983/api/cluster/configs/genome_set?omitHeader=true'
For more detail, https://lucene.apache.org/solr/guide/7_5/configsets-api.html
$ curl 'http://localhost:8983/solr/admin/collections?action=CREATE&name=genome&numShards=1&replicationFactor=1&collection.configName=genome_set'
Here is some other operations,
# list collections
$ curl 'http://localhost:8983/solr/admin/collections?action=LIST'
# delete a collection
$ curl 'http://localhost:8983/solr/admin/collections?action=DELETE&name=genome'
For more detail, refer the Collections API https://lucene.apache.org/solr/guide/7_5/collections-api.html