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The dynamic landscape of peptide function prediction

This curated list collects peer-reviewed machine learning models dedicated to predicting specific properties of peptides. For an interactive and browse-able list, please visit: https://biogenies.info/peptide-prediction-list/.

Antiangiogenic peptides

  1. AntAngioCOOL (2019): publication; model repository.
  2. AntiAngioPred (2015): publication; web server.
  3. Pep-CNN (2022): publication; training repository; model repository.
  4. PEPred-Suite (2019): publication; web server.
  5. PPTPP (2020): publication; training repository; model repository.
  6. TargetAntiAngio (2019): publication; training repository; model repository; web server.
  7. TPpred-ATMV (2022): publication; model repository.
  8. Zhang et al. (2018): publication.

Antibacterial peptides (ABP)

  1. ClassAMP (2012): publication; web server.
  2. Deep-ABPpred (2021): publication; web server.
  3. iAMP-CA2L (2021): publication; training repository; model repository; web server.
  4. iAMPpred (2017): publication; web server.
  5. MAMPs-Pred (2019): publication.
  6. Pep-CNN (2022): publication; training repository; model repository.
  7. PEPred-Suite (2019): publication; web server.
  8. PPTPP (2020): publication; training repository; model repository.
  9. PreTP-EL (2021): publication; web server.
  10. PreTP-Stack (2022): publication; web server.
  11. StaBle-ABPpred (2021): publication; web server.
  12. TP-MV (2022): publication.
  13. TPpred-ATMV (2022): publication; model repository.
  14. Zhang et al. (2021): publication; training repository; model repository.

Antibiofilm peptides

  1. dPABBs (2016): publication; web server.
  2. iAMP-CA2L (2021): publication; training repository; model repository; web server.

Anticancer peptides (ACP)

  1. ACHP (2021): publication; web server.
  2. ACP-2DCNN (2022): publication.
  3. ACP-DA (2021): publication; model repository.
  4. ACP-DL (2019): publication; training repository; model repository.
  5. ACP-MHCNN (2021): publication; training repository; model repository; web server.
  6. ACPNet (2022): publication; training repository; model repository.
  7. ACPP (2014): publication; web server.
  8. ACPred (2019): publication; web server.
  9. ACPred-FL (2018): publication; web server.
  10. ACPred-Fuse (2019): publication; web server.
  11. AntiCP (2013): publication; web server.
  12. AntiCP 2.0 (2020): publication; model repository; web server.
  13. cACP-2LFS (2020): publication; training repository; model repository.
  14. CancerGram (2020): publication; training repository; model repository; web server.
  15. DeepACP (2020): publication; training repository; model repository.
  16. DLACP (2020): publication.
  17. DLFF-ACP (2021): publication; training repository; model repository.
  18. DRACP (2020): publication.
  19. Hajisharifi et al. (2014): publication.
  20. iACP (2016): publication; web server.
  21. iACP-DRLF (2021): publication; model repository.
  22. iACP-FSCM (2021): publication; training repository; model repository; web server.
  23. iACP-GAEnsC (2017): publication.
  24. iAMP-CA2L (2021): publication; training repository; model repository; web server.
  25. Khan et al. (2017): publication.
  26. Li & Wang (2016): publication.
  27. Li et al. (2020): publication.
  28. mACPpred (2019): publication; web server.
  29. MAMPs-Pred (2019): publication.
  30. ME-ACP (2022): publication; training repository; model repository.
  31. MLACP (2017): publication; web server.
  32. MLBP (2021): publication; training repository; model repository; web server.
  33. MPMABP (2022): publication; training repository; model repository.
  34. Pep-CNN (2022): publication; training repository; model repository.
  35. PPTPP (2020): publication; training repository; model repository.
  36. PreTP-EL (2021): publication; web server.
  37. PreTP-Stack (2022): publication; web server.
  38. SAP (2018): publication.
  39. StackACPred (2022): publication; training repository; model repository.
  40. TargetACP (2018): publication.
  41. TPpred-ATMV (2022): publication; model repository.
  42. xDeep-AcPEP (2021): publication; training repository; model repository; web server.

Antifungal peptides (AFP)

  1. Antifp (2018): publication; web server.
  2. ClassAMP (2012): publication; web server.
  3. Deep-AFPpred (2021): publication; web server.
  4. Deep-AntiFP (2021): publication; model repository.
  5. iAFPs-EnC-GA (2022): publication; model repository.
  6. iAMP-CA2L (2021): publication; training repository; model repository; web server.
  7. iAMPpred (2017): publication; web server.
  8. Mousavizadegan & Mohabatkar (2018): publication.
  9. PEPred-Suite (2019): publication; web server.
  10. TCN-AFPpred (2022): publication; web server.

Antihypertensive peptides

  1. ACHP (2021): publication; web server.
  2. mAHTPred (2018): publication; web server.
  3. MLBP (2021): publication; training repository; model repository; web server.
  4. MPMABP (2022): publication; training repository; model repository.
  5. PAAP (2018): publication; training repository; model repository; web server.
  6. Rauf et al. (2021): publication.
  7. Wang et al. (2021): publication.

Antiinflammatory peptides (AIP)

  1. AIEpred (2021): publication; training repository; model repository.
  2. AIPpred (2018): publication; web server.
  3. AntiFlamPred (2021): publication.
  4. AntiInflam (2017): publication; web server.
  5. MLBP (2021): publication; training repository; model repository; web server.
  6. MPMABP (2022): publication; training repository; model repository.
  7. Pep-CNN (2022): publication; training repository; model repository.
  8. PEPred-Suite (2019): publication; web server.
  9. PPTPP (2020): publication; training repository; model repository.
  10. PreAIP (2019): publication; web server.
  11. PreTP-EL (2021): publication; web server.
  12. PreTP-Stack (2022): publication; web server.
  13. TPpred-ATMV (2022): publication; model repository.

Antimicrobial peptides (AMP)

  1. ACEP (2020): publication; training repository; model repository.
  2. AI4AMP (2021): publication; training repository; model repository; web server.
  3. AMAP (2019): publication; web server.
  4. AMP0 (2022): publication; web server.
  5. AMPDiscover (2021): publication; web server.
  6. AmPEP (2018): publication; model repository; web server.
  7. amPEPpy 1.0 (2020): publication; training repository; model repository.
  8. AmpGram (2020): publication; training repository; model repository; web server.
  9. Ampir (2020): publication; training repository; model repository; web server.
  10. AMPlify (2022): publication; training repository; model repository.
  11. AMPpred-EL (2022): publication.
  12. AMPScanner V2 (2018): publication; web server.
  13. ANFIS (2012): publication.
  14. AniAMPpred (2021): publication; web server.
  15. APIN (2019): publication; training repository; model repository.
  16. CAMP (2009): publication.
  17. CAMPR3 (2015): publication; web server.
  18. ClassAMP (2012): publication; web server.
  19. Co-AMPpred (2021): publication; training repository; model repository.
  20. CS-AMPPred (2012): publication; model repository.
  21. DBAASP (2014): publication; web server.
  22. Deep-AmPEP30 (2020): publication; training repository; model repository; web server.
  23. Ensemble-AMPPred (2021): publication; training repository; model repository.
  24. Healy et al. (2021): publication; model repository.
  25. iAMP-2L (2013): publication; web server.
  26. iAMP-CA2L (2021): publication; training repository; model repository; web server.
  27. IAMPE (2020): publication; web server.
  28. Ma et al. (2022): publication; model repository.
  29. Maccari et al. (2013): publication.
  30. Macrel (2020): publication; training repository; model repository; web server.
  31. MAMPs-Pred (2019): publication.
  32. MLAMP (2016): publication; web server.
  33. MLBP (2021): publication; training repository; model repository; web server.
  34. MPMABP (2022): publication; training repository; model repository.
  35. Ng et al. (2015): publication.
  36. PepVAE3 (2021): publication.
  37. sAMP-PFPDeep (2021): publication; model repository.
  38. Wang et al. (2011): publication; web server.
  39. Wani et al. (2021): publication; model repository.
  40. Zhang et al. (2021): publication; training repository; model repository.

Antiparasitic peptides (APP)

  1. i2APP (2022): publication; training repository; model repository.
  2. MAMPs-Pred (2019): publication.
  3. PredAPP (2021): publication; training repository; model repository; web server.

Antiviral peptides (AVP)

  1. AntiVPP 1.0 (2019): publication; model repository.
  2. AVP‐IC50Pred (2015): publication; web server.
  3. AVPIden (2021): publication; model repository; web server.
  4. AVPpred (2012): publication; web server.
  5. Bakare et al. (2021): publication.
  6. ClassAMP (2012): publication; web server.
  7. DeepAVP (2020): publication; web server.
  8. ENNAVIA (2021): publication; web server.
  9. FIRM-AVP (2020): publication; training repository; model repository; web server.
  10. iACVP (2022): publication; training repository; model repository; web server.
  11. iAMPpred (2017): publication; web server.
  12. MAMPs-Pred (2019): publication.
  13. Meta-iAVP (2019): publication; web server.
  14. Pep-CNN (2022): publication; training repository; model repository.
  15. PEPred-Suite (2019): publication; web server.
  16. PPTPP (2020): publication; training repository; model repository.
  17. PreAntiCoV (2021): publication; training repository; model repository.
  18. PreTP-EL (2021): publication; web server.
  19. PreTP-Stack (2022): publication; web server.
  20. TPpred-ATMV (2022): publication; model repository.

Blood-brain barrier peptides (BBP)

  1. B3Pred (2021): publication; web server.
  2. BBPpred (2021): publication; web server.
  3. Zou (2021): publication.

Cell-penetrating peptides (CPP)

  1. BChemRF-CPPred (2021): publication; web server.
  2. CPPred-RF (2017): publication; web server.
  3. ITP-Pred (2020): publication.
  4. KELM-CPPpred (2018): publication; web server.
  5. Liu et al. (2022): publication.
  6. MLCPP (2018): publication; web server.
  7. MLCPP 2.0 (2022): publication; web server.
  8. Pep-CNN (2022): publication; training repository; model repository.
  9. PEPred-Suite (2019): publication; web server.
  10. PPTPP (2020): publication; training repository; model repository.
  11. PreTP-EL (2021): publication; web server.
  12. PreTP-Stack (2022): publication; web server.
  13. SkipCPP-Pred (2017): publication; web server.
  14. TargetCPP (2020): publication; training repository; model repository.
  15. TP-MV (2022): publication.
  16. TPpred-ATMV (2022): publication; model repository.
  17. GraphCPP (2024): publication; model repository; data repository.

Chemotactic peptides

  1. iAMP-CA2L (2021): publication; training repository; model repository; web server.

Neuropeptides peptides

  1. NeuroPIpred (2019): publication; web server.
  2. NeuroPP (2018): publication; web server.
  3. NeuroPpred-Fuse (2021): publication; model repository.
  4. NeuroPred-FRL (2021): publication; web server.
  5. PredNeuroP (2020): publication; training repository; model repository.

Quorum sensing peptides

  1. EnsembleQS (2022): publication; training repository; model repository.
  2. iQSP (2019): publication; web server.
  3. ITP-Pred (2020): publication.
  4. Pep-CNN (2022): publication; training repository; model repository.
  5. PEPred-Suite (2019): publication; web server.
  6. PPTPP (2020): publication; training repository; model repository.
  7. PreTP-EL (2021): publication; web server.
  8. PreTP-Stack (2022): publication; web server.
  9. QSPpred (2015): publication; web server.
  10. QSPred-FL (2018): publication; web server.
  11. TP-MV (2022): publication.
  12. TPpred-ATMV (2022): publication; model repository.

Surface-binding peptides

  1. Pep-CNN (2022): publication; training repository; model repository.
  2. PEPred-Suite (2019): publication; web server.
  3. PPTPP (2020): publication; training repository; model repository.
  4. PreTP-EL (2021): publication; web server.
  5. PreTP-Stack (2022): publication; web server.
  6. TPpred-ATMV (2022): publication; model repository.

Toxic peptides (TP)

  1. ATSE (2021): publication; web server.
  2. ToxIBTL (2022): publication; model repository; web server.
  3. ToxinPred (2014): publication; web server.

About and citation

This website accompanies our publication: The dynamic landscape of peptide function prediction.

Citation: Oriol Bárcenas, Carlos Pintado-Grima, Katarzyna Sidorczuk, Felix Teufel, Henrik Nielsen, Salvador Ventura and Michał Burdukiewicz, The dynamic landscape of peptide function prediction, Computational and Structural Biotechnology Journal, 10.1016/j.csbj.2022.11.043.