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btm_annotation_table.csv
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ID;Module title;Composite name;Module size;Module category;Annotation level;Web link;Module member genes;Top matched pathway in KEGG, PID and BIOCARTA;Jaccard Index;Enrichment p value;Pathway size;Overlap size;Top matched Chaussabel module;Jaccard Index;Enrichment p value;Module size;Overlap size;Top matched Transcription Factor;Jaccard Index;Enrichment p value;Gene set size;Overlap size;Top matched Gene Ontology terms (number of matched genes)
M0;targets of FOSL1/2;targets of FOSL1/2 (M0);12;TF targets;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M0.htm;CCL2,DCN,LIF,PLAU,IL6,MGP,COL1A2,MMP9,THBD,MMP2,IL8,MMP1;[PID]Validated transcriptional targets of AP1 family members Fra1 and Fra2;0;0;36;12;;;;;;AML_Q6;0;0;204;3;extracellular space (11), extracellular region (11), protein binding (9)
M1.0;integrin cell surface interactions (I);integrin cell surface interactions (I) (M1.0);29;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M1.0.htm;ITGA9,PDGFRA,PTK2,TNC,PDGFRB,EGFR,ITGA5,LAMB1,COL3A1,LAMB2,CAV2,MYL9,ITGA2B,KDR,ITGB3,COL5A2,COL5A1,COL4A2,COL4A1,LAMC1,FN1,CCND2,ITGAV,MET,COL1A2,COL1A1,COL6A1,COL6A3,COL6A2;KEGG_FOCAL_ADHESION;0;0;201;29;;;;;;;;;;;protein binding (26), axon guidance (20), extracellular region (16)
M1.1;integrin cell surface interactions (II);integrin cell surface interactions (II) (M1.1);12;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M1.1.htm;LAMC1,TNC,FN1,FBN1,COL4A5,COL1A2,COL4A2,COL4A1,COL1A1,LAMB1,VWF,LAMB2;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;10;;;;;;CP2_01;0;0;198;3;protein binding (12), extracellular region (12), extracellular matrix structural constituent (9)
M2.0;extracellular matrix (I);extracellular matrix (I) (M2.0);30;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M2.0.htm;CDH11,PDGFRB,PDGFRA,VCAN,BGN,AEBP1,COL3A1,THBS1,LUM,DCN,THBS2,FSTL1,NID2,NID1,PCOLCE,SPP1,PDGFC,LAMA4,FBN1,COL5A2,COL5A1,COL4A2,COL4A1,MXRA8,COL1A2,COL1A1,COL6A1,COL6A3,COL6A2,MMP2;KEGG_FOCAL_ADHESION;0;0;201;17;;;;;;;;;;;protein binding (27), extracellular region (26), extracellular matrix (21)
M2.1;extracellular matrix (II);extracellular matrix (II) (M2.1);45;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M2.1.htm;TNFSF13,CD40LG,MPO,VCAN,TFF3,AEBP1,OLFM4,COL3A1,LOX,TNFAIP2,HTRA1,LILRB2,PLA2G7,CHIT1,THBS2,RETN,NID2,NID1,CRISP3,CST3,CTSH,LAMA4,ENTPD1,FBN1,COL5A2,POSTN,COL5A1,COL4A2,CEACAM8,GRN,ACHE,LRG1,CTSG,CXCL1,SMPDL3A,ORM1,ARG1,SPARC,FGL2,COL1A2,ANGPTL2,COL1A1,TGFBI,COL6A2,MMP2;;;;;;;;;;;;;;;;extracellular region (38), extracellular space (31), protein binding (29)
M2.2;extracellular matrix (III);extracellular matrix (III) (M2.2);14;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M2.2.htm;CDH11,DCN,LAMA4,VCAN,FBN1,COL5A2,NID2,COL5A1,COL1A2,ANGPTL2,COL3A1,EDNRA,AEBP1,MMP1;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;5;;;;;;;;;;;extracellular region (12), protein binding (11), extracellular matrix (10)
M3;regulation of signal transduction;regulation of signal transduction (M3);47;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M3.htm;PTK2,TIMP2,WLS,KIF26A,ECM1,GAB1,CCR1,FOXO1,C5AR1,APCDD1,S100A12,SOX7,PLXNB2,FZD8,TRAT1,CSF1R,SULF2,CDK14,PSD3,JUP,ADAP2,NOD2,TIAM2,LYN,FGD4,ENG,FPR1,KLF4,PRKCD,UBASH3A,SHANK3,GATA3,GH1,HPSE,IL1RN,LRP1,BMP2,SYK,HMOX1,TLR2,RGL1,CTGF,ZNF423,TLR5,BCL6,CD3E,ASAP2;;;;;;;;;;;;;;;;protein binding (39), plasma membrane (24), cytoplasm (23)
M4.0;cell cycle and transcription;cell cycle and transcription (M4.0);335;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.0.htm;FXYD6,FAM198B,HSPA6,BUB1B,PLK1,NUF2,CD33,TIMP2,PLK4,CD36,C5AR1,FCGR1B,FCGR1A,S100A11,SEMA4A,MAFB,S100A12,KIF2C,CPPED1,SKA1,TPX2,CCDC99,NUSAP1,TYROBP,UBE2T,FGR,MARCKS,ESPL1,C15orf42,DLGAP5,IRAK3,SIRPA,CDCA7,BRCA1,CENPN,CENPM,CENPK,OIP5,CENPI,CENPH,CENPF,ALOX5,NOD2,MYBL2,ITGAX,CENPA,CLEC4E,SPAG5,ZWINT,CSF3R,CENPW,SLC15A3,DEPDC1B,KIFC1,HPSE,KCTD12,TNFAIP2,LST1,CD300LF,ORC1L,WHSC1,RBM47,H2AFX,SECTM1,KIF23,RAB31,TLR2,CD163,CCNF,DAPK1,TLR4,GLT1D1,CHAC2,PTAFR,TLR8,TOP2A,TCF19,SPC24,SPC25,CDC20,TNFSF13,C16orf75,CD1D,CSF2RA,STMN1,IGSF6,DTL,PTTG3P,EMR2,RASSF4,TROAP,SLC31A2,FEN1,FAM64A,TMEM106C,FGL2,RIN2,POLA2,LY86,PLXNB2,STIL,LILRB3,LILRB2,LILRB1,CLEC7A,CCNE2,EXO1,TIMELESS,RNF130,PAICS,TNS3,CEACAM8,NEK2,DONSON,HNMT,WDFY3,CHEK1,GCA,FCN1,SUV39H2,BUB1,TFEC,CDC25C,CDC25A,NCAPH,SGOL2,RTN1,NCAPG,NCF1C,PGLYRP1,GRN,HCK,KIF18B,KIF15,PBK,LOC100288693,GINS2,IL1RN,IL13RA1,GINS1,RNASEH2A,GINS4,NPL,TIPIN,KIF20B,UBE2C,HMOX1,CD93,APITD1,MELK,CD14,DEPDC1,SIRPB2,POLE2,FPR1,KNTC1,SORT1,UBE2S,KIF20A,AIF1,MCM2,NCF2,NCF1,SMC2,POLQ,MKI67,RFC5,CSF1R,TK1,TMPO,RFC3,KIF14,CCR1,C21orf45,CD302,FOXM1,FBXO5,FANCD2,ZWILCH,GMNN,BRIP1,KIAA0101,WDHD1,NDC80,CDC6,CDC7,SCPEP1,FCER1G,SPI1,CYP1B1,RACGAP1,ASPM,FAM54A,ERCC6L,CDT1,CKS1B,MCM4,CD86,PRIM1,RAD51AP1,S100A9,SLC7A7,CST3,GGH,FANCI,E2F7,EPB41L3,MTMR11,LMNB2,CKS2,WDR76,CSTA,HMMR,RXRA,CCDC34,ASGR1,ASGR2,LMNB1,KIF11,FES,PTTG1,LGALS2,PADI4,UHRF1,C11orf82,KIAA1598,SHCBP1,LMO2,TACC3,APOBEC3A,LRRC25,ALDH2,APOBEC3B,CDK1,FAM72A,ARHGAP11A,RAD51,CDC45,PILRA,GPSM2,CKAP2L,DSCC1,TYMS,CTSH,POLA1,MAD2L1,STAB1,HELLS,DHFR,PLAUR,BIRC5,CEP55,VCAN,KIAA1524,EZH2,RRM2,RRM1,NLRP12,SYK,PRC1,ATAD2,ZNF367,MYOF,FAM83D,SERPINA1,CEBPA,DNA2,CCNA2,PLBD1,ECT2,CEBPD,CDKN3,TBXAS1,DIAPH3,TTK,TNFSF12-TNFSF13,KIF4A,RMI1,CDCA2,CDCA3,SKA3,KLF4,AURKA,AURKB,CDCA5,MNDA,POC1A,CDCA8,FCGRT,CENPE,ASF1B,PCNA,C1orf112,MCM10,MS4A6A,NEIL3,MND1,MPEG1,ANLN,KIF18A,PRKCD,FCGR2A,CYBB,MCM6,MCM5,KYNU,NCAPG2,IFI30,CASC5,TGFBI,HJURP,TRIP13,PPIL5,CPVL,DMXL2,CCNB2,CCNB1,AOAH,CHST15,E2F2,C12orf48,CFD,SLC11A1,RFC4,CLEC4A,E2F8,RAD54L,TYMP,LILRA6,MLF1IP,SEPX1,SIGLEC7,LILRA2,CFP,LILRA1;;;;;;;;;;;;;;;;protein binding (217), nucleus (160), cytoplasm (122)
M4.1;cell cycle (I);cell cycle (I) (M4.1);145;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.1.htm;BUB1B,PLK1,PLK4,KIF2C,SKA1,TPX2,CCDC99,ESPL1,DLGAP5,BRCA1,CENPN,CENPM,CENPK,OIP5,CENPI,CENPH,CENPF,CENPE,SPAG5,MYBL2,CENPA,CENPW,KIFC1,H2AFX,KIF23,CCNF,NCAPH,NCAPG,TOP2A,SPC24,SPC25,KIF11,NCAPG2,STMN1,DTL,ZWINT,FEN1,NEK2,CCNE2,EXO1,TIMELESS,TTK,TYMS,CHEK1,SUV39H2,BUB1,CDC25C,CDC25A,SGOL2,NCAPD3,ZWILCH,PBK,GINS2,GINS1,GINS4,GPSM2,UBE2C,CDC20,MELK,DTYMK,POLE2,UBE2S,DSCC1,SMC2,POLA2,RFC5,CDT1,RFC3,SMC4,KIF15,PRKAR2B,FOXM1,FBXO5,FANCD2,GMNN,BRIP1,NDC80,CDC6,CDC7,NUSAP1,RACGAP1,ASPM,ERCC6L,KNTC1,CKS1B,PRIM1,RANBP1,FANCI,HELLS,CKS2,PTTG1,UHRF1,C11orf82,TACC3,CDK1,RAD51,CDC45,KIF20B,KIF20A,MKI67,POLA1,MAD2L1,DHFR,BIRC5,CEP55,RRM2,CHAF1B,PRC1,APITD1,FAM83D,DNA2,CCNA2,ECT2,TIPIN,CDKN3,NUF2,CDCA2,CDCA3,SKA3,AURKA,AURKB,CDCA5,CDCA8,PCNA,MCM10,MND1,ANLN,KIF18A,KIF18B,MCM6,MCM5,MCM4,MCM2,CASC5,HJURP,TRIP13,E2F7,CCNB2,CCNB1,E2F2,RFC4,E2F8,TUBG1,RAD54L,MLF1IP;;;;;;;;;;;;;;;;protein binding (117), nucleus (114), cytoplasm (80)
M4.2;PLK1 signaling events;PLK1 signaling events (M4.2);34;signaling;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.2.htm;BUB1B,PLK1,CEP55,KIF14,FBXO5,PRC1,MYBL2,NDC80,TPX2,HJURP,ECT2,ASPM,ERCC6L,RAD51AP1,ESPL1,AURKA,WEE1,CLSPN,ASF1B,BUB1,CDC25C,CENPE,SGOL1,NUSAP1,TRIP13,GINS2,KIF23,CDC20,TUBG1,NCAPG,MLF1IP,CKAP2L,SPC25,KIF20A;[PID]PLK1 signaling events;0;0;27;16;[Chaussabel.v2]M3.3;0;0;49;11;;;;;;protein binding (31), nucleus (27), cytoplasm (21)
M4.3;myeloid cell enriched receptors and transporters;myeloid cell enriched receptors and transporters (M4.3);31;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.3.htm;CD1D,SLC7A7,AMICA1,CCR1,LRRC25,GPBAR1,MYOF,MARCO,SULF2,CD86,SLC1A3,SLC8A1,IGSF6,MPEG1,MTMR11,RNASE6,SLC24A4,SIGLEC16,ASGR1,SLC15A3,KCTD12,CHST15,SLC2A6,SECTM1,CLEC4A,CD14,TLR5,TLR8,SIGLEC7,MS4A14,LILRA1;;;;;;[Chaussabel.v2]M4.14;0;0;59;8;;;;;;integral to membrane (19), membrane (17), protein binding (16)
M4.4;mitotic cell cycle - DNA replication;mitotic cell cycle - DNA replication (M4.4);30;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.4.htm;POLA2,POLA1,PLK4,KIF15,CDC6,CDC7,STIL,EXO1,CDT1,ORC6L,PRIM1,PRIM2,PCNA,C1orf112,MCM10,OIP5,MND1,TPX2,MCM7,MCM6,MCM5,MCM4,MCM3,MCM2,MCM8,C12orf48,RPA2,CDK2,POLE2,CDC45;KEGG_DNA_REPLICATION;0;0;36;13;;;;;;E2F_Q3;0;0;166;11;nucleus (24), protein binding (22), nucleoplasm (20)
M4.5;mitotic cell cycle in stimulated CD4 T cells;mitotic cell cycle in stimulated CD4 T cells (M4.5);35;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.5.htm;MAD2L1,CEP55,HNRPLL,LAG3,GPR56,KIAA0101,NDC80,TYMS,FBXO5,MELK,GRAP2,CDCA7,CDCA5,RRM2,CXCR6,MIR155HG,CENPM,CENPK,NUF2,IFNG,ZNF367,MCM6,ENO2,KIF11,DEPDC1B,ZEB1,UHRF1,TACC3,CDC20,CDK1,RNF144A,CHAC2,TOP2A,UBE2T,KIF20A;;;;;;[Chaussabel.v2]M3.3;0;0;49;11;;;;;;protein binding (19), nucleus (16), cytoplasm (16)
M4.6;cell division in stimulated CD4 T cells;cell division in stimulated CD4 T cells (M4.6);20;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.6.htm;BRCA1,GINS2,CENPM,BRCA2,CDKN3,ANLN,CEP55,HMMR,POLE2,CDCA2,GINS1,NCAPG2,CDCA7,FANCD2,UBE2T,DEPDC1B,FANCL,FAM72A /// FAM72B /// FAM72C /// FAM72D,FANCI,DSCC1;;;;;;[Chaussabel.v2]M3.3;0;0;49;6;;;;;;nucleus (14), protein binding (11), nucleoplasm (10)
M4.7;mitotic cell cycle;mitotic cell cycle (M4.7);21;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.7.htm;CCNB2,CCNB1,CCNA2,SHCBP1,PLK1,CDC25C,CDC25A,EXO1,CDT1,CEP152,PKMYT1,E2F8,TUBG1,CDK1,CEP76,FOXM1,SGOL2,CEP72,NEK2,PLK4,CKAP5;KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION;0;0;86;8;;;;;;;;;;;protein binding (20), mitotic cell cycle (17), nucleus (15)
M4.8;cell division - E2F transcription network;cell division - E2F transcription network (M4.8);19;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.8.htm;E2F7,PCNA,NASP,MAD2L1,CASP2,TOPBP1,RFC5,TIMELESS,DNMT1,H2AFX,KIF4A,PRKDC,MCM4,DTYMK,MCM2,ZWINT,RNASEH2A,MCM3,RANBP1;KEGG_DNA_REPLICATION;0;0;36;6;;;;;;E2F_01;0;0;56;13;nucleus (18), protein binding (17), DNA binding (11)
M4.9;mitotic cell cycle in stimulated CD4 T cells;mitotic cell cycle in stimulated CD4 T cells (M4.9);16;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.9.htm;RBBP8,CCDC99,CENPF,CENPE,MASTL,PLK4,ZNF367,KIF14,EZH2,RAD51,NCAPH,GMNN,TRIP13,RRM1,CDC6,DONSON;;;;;;;;;;;E2F_Q3;0;0;166;6;nucleus (14), protein binding (10), cytoplasm (10)
M4.10;cell cycle (II);cell cycle (II) (M4.10);14;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.10.htm;BRCA1,CCNB2,CCNB1,DTL,CCNE2,CDC25A,CCNE1,GINS2,CDK1,PERP,MELK,RRM2,STEAP3,CHEK1;KEGG_P53_SIGNALING_PATHWAY;0;0;69;9;[Chaussabel.v2]M3.3;0;0;49;6;;;;;;protein binding (12), nucleus (11), cytoplasm (10)
M4.11;mitotic cell cycle in stimulated CD4 T cells;mitotic cell cycle in stimulated CD4 T cells (M4.11);12;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.11.htm;CCNA2,CCDC99,MELK,RAD54L,GSG2,SUV39H1,CYB5B,CDCA3,AURKB,TK1,STMN1,RAD51C;;;;;;[Chaussabel.v2]M3.3;0;0;49;4;MCAATNNNNNGCG_UNKNOWN;0;0;66;4;cytoplasm (8), nucleus (7), protein binding (6)
M4.12;C-MYC transcriptional network;C-MYC transcriptional network (M4.12);12;TF targets;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.12.htm;CCNB1,NME1,CKS2,BIRC5,CENPA,HMGA1,MCM6,KIF11,BCAT1,TK1,TOP2A,CDCA7;[PID]Validated targets of C-MYC transcriptional activation;0;0;69;7;[Chaussabel.v2]M3.3;0;0;49;5;E2F1DP2_01;0;0;127;3;nucleus (8), cytosol (8), protein binding (7)
M4.13;cell junction (GO);cell junction (GO) (M4.13);11;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.13.htm;LCP1,KCTD12,EPB41L3,PRKCD,IFI30,PAK1,FES,TNS3,HCK,HOMER3,CTNNA1;KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS;0;0;97;3;;;;;;ZF5_01;0;0;183;3;protein binding (10), plasma membrane (8), cytoplasm (7)
M4.14;Rho GTPase cycle;Rho GTPase cycle (M4.14);10;signaling;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.14.htm;E2F2,ECT2,RACGAP1,CEP55,DEPDC1,ARHGAP11A,DEPDC1B,PRC1,C11orf82,ARHGAP19;;;;;;;;;;;;;;;;signal transduction (6), nucleus (6), intracellular (6)
M4.15;enriched in monocytes (I);enriched in monocytes (I) (M4.15);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M4.15.htm;TNFSF13,MYCL1,EPB41L3,DPYSL2,RTN1,SLC31A2,FES,LGALS3,HCK,APLP2,LGALS1;;;;;;;;;;;GTGGGTGK_UNKNOWN;0;0;225;3;protein binding (9), cytoplasm (5), signal transduction (4)
M5.0;regulation of antigen presentation and immune response;regulation of antigen presentation and immune response (M5.0);81;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M5.0.htm;NCKAP1L,THEMIS,HLA-DPB1,JUN,NFKBIA,PTPN6,TLR5,HLA-DRA,CD4,PRKCQ,PLCG1,CD247,TRBC1,FCGR1B,CCR7,TLR6,TLR10,FYB,TLR2,FCER1G,TRAT1,LILRB2,LILRB1,CLEC7A,BTLA,FYN,FGR,CD86,GRAP2,HLA-DQB1,ZAP70,PAG1,MNDA,IRAK3,LCK,DUSP6,PTPN22,PAK1,CTSH,CTLA4,LCP2,TLR4,CSK,FOS,LAT2,CARD11,HLA-DRB1,CHUK,CD24,UBASH3A,MAP2K6,TLR7,LY96,HCK,VASP,LYN,LIME1,MAPK14,MYD88,INPP5D,ITK,TRAC,SLA2,KLRK1,HLA-DMB,RPS6KA1,HLA-DQA1,MEF2C,SYK,MEF2A,TLR1,PTPRC,HLA-DOA,HLA-DOB,HLA-DMA,HLA-DPA1,CD19,CD3D,CD3E,BTK,CD3G;KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;108;23;;;;;;;;;;;protein binding (72), plasma membrane (57), T cell receptor signaling pathway (36)
M5.1;T cell activation and signaling;T cell activation and signaling (M5.1);25;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M5.1.htm;CD52,CD4,CD247,CD2,CCR7,BIN2,HLA-DRA,IL12RB1,TRAT1,ZAP70,TRAF3IP3,HLA-DRB1,PRKAR1B,GIMAP6,TRA@,ITK,IL2RG,TRA@ /// TRAC,CD3E,TRA@ /// TRAC /// TRAJ17 /// TRAV20,PTPRC,PRKACB,CD3D,LCK,CD3G;BIOCARTA_CSK_PATHWAY;0;0;24;13;;;;;;;;;;;protein binding (16), plasma membrane (16), T cell receptor signaling pathway (12)
M6;mitotic cell division;mitotic cell division (M6);32;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M6.htm;MAD2L1,BUB1B,PLK1,ZWINT,BIRC5,CENPK,CDC20,NDC80,KIF2C,CCDC99,ERCC6L,SKA1,AURKB,CDCA8,CENPO,CENPN,CENPM,BUB1,CENPI,CENPH,CENPF,CENPE,KIF18A,CENPA,SGOL2,CASC5,ZWILCH,NUF2,APITD1,MLF1IP,SPC25,SPC24;;;;;;;;;;;;;;;;mitotic prometaphase (31), mitotic cell cycle (31), cytosol (31)
M7.0;enriched in T cells (I);enriched in T cells (I) (M7.0);62;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M7.0.htm;IL7R,KLRB1,CCL5,RASGRP1,TRA@,SH2D1A,TRAV20,BCL11B,CD6,CD7,TRBC1,CD2,LEF1,NKG7,UBASH3A,PTPRCAP,TRAC,TRD@,TRAT1,SLA2,RORA,MAL,EOMES,XCL2,XCL1,ETS1,ZAP70,SAMD3,SIT1,NLRC3,SIRPG,PRKCH,ICOS,CD28,TRAJ17,NELL2,GNLY,CD27,LAT,FLT3LG,PRF1,PRKCQ,GIMAP6,GIMAP7,GATA3,ITK,LCK,GZMA,GZMB,CD96,GZMM,GZMH,TIGIT,GZMK,ITM2A,CD247,GPR171,IL32,TARP,CD3D,CD3E,CD3G;;;;;;[Chaussabel.v2]M4.15;0;0;42;16;;;;;;protein binding (36), plasma membrane (28), integral to membrane (15)
M7.1;T cell activation (I);T cell activation (I) (M7.1);50;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M7.1.htm;IL7R,RASGRP1,THEMIS,CCL5,TCF7,BCL11B,CD5,TIGIT,CD7,CD2,CCR7,CD247,MS4A1,PTPN22,TXK,TRBC1,IL12RB1,IKZF1,SLA2,CAMK4,RORA,EOMES,PRKCQ,ZAP70,SIT1,NLRC3,DPP4,SIRPG,PRKCH,ICOS,CD28,CD27,RHOH,CD8A,ITPR3,LEF1,CD8B,GATA3,CRTAM,ITK,TRAC,KLRK1,IL21R,LCK,CORO1A,SLAMF7,CD3D,CD3E,SLAMF1,CD3G;KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;108;13;;;;;;;;;;;protein binding (41), plasma membrane (31), cytoplasm (19)
M7.2;enriched in NK cells (I);enriched in NK cells (I) (M7.2);49;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M7.2.htm;TGFBR3,KLRB1,KLRD1,CCL5,TBX21,FCGR3B,PTGDR,CD247,NLRC3,GPR56,MYBL1,ARL4C,KLRF1,STAT4,PLEKHF1,IL18RAP,RORA,EOMES,XCL2,XCL1,FGFBP2,SAMD3,CTSW,CST7,ZAP70,KLRC1,PRKCH,S1PR5,CLIC3,TRD@,GNLY,SH2D2A,FASLG,PRF1,PRKCQ,GIMAP7,GZMA,IL2RB,HOPX,ITK,GZMB,NKG7,CD96,GZMM,GZMH,KLRK1,SLAMF7,TRA@,TARP;;;;;;[Chaussabel.v2]M3.6;0;0;47;21;;;;;;protein binding (27), plasma membrane (21), cytoplasm (15)
M7.3;T cell activation (II);T cell activation (II) (M7.3);31;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M7.3.htm;CCL5,SP140,TIGIT,CD247,CCR5,NLRC3,PTPRCAP,STAT4,IL12RB1,TRAT1,SLA2,CXCR3,ZAP70,NKG7,SIRPG,ICOS,IFNG,IL18R1,SLAMF7,PTPN7,ITK,CRTAM,GZMA,CD3E,GPR171,TRA@,TARP,CD3D,LCK,SLAMF1,CD3G;BIOCARTA_IL12_PATHWAY;0;0;23;11;;;;;;;;;;;protein binding (22), plasma membrane (21), integral to membrane (14)
M7.4;T cell activation (III);T cell activation (III) (M7.4);14;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M7.4.htm;KLF12,RASGRP1,THEMIS,NELL2,CD96,CAMK4,RORA,LCK,ATP8B2,ETS1,ZMYND11,PRKCQ,LEF1,GLYR1 /// SEPT6;;;;;;[Chaussabel.v2]M4.15;0;0;42;5;ZIC1_01;0;0;203;5;protein binding (11), nucleus (8), cytoplasm (6)
M8;E2F transcription factor network;E2F transcription factor network (M8);18;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M8.htm;BRCA1,CCNA2,E2F2,E2F1,MELK,ORC1L,ZWINT,CDC25A,ERCC6L,ORC6L,C12orf48,KIAA1524,RAD54L,CDCA5,UBE2C,KIAA0101,FAM54A,CDC6;[PID]E2F transcription factor network;0;0;55;6;[Chaussabel.v2]M3.3;0;0;49;7;E2F_Q6_01;0;0;170;6;protein binding (12), nucleus (11), cytoplasm (10)
M9;B cell development;B cell development (M9);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M9.htm;TNFSF13,LIF,HHEX,CEBPE,CBFA2T3,LTA,SPI1,TLR4,CCR7,LYN,TNF;;;;;;;;;;;PU1_Q6;0;0;182;5;protein binding (8), immune response (6), signal transduction (5)
M10.0;E2F1 targets (Q3);E2F1 targets (Q3) (M10.0);33;TF targets;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M10.0.htm;MAP4K1,STMN1,ERBB2IP,RFC1,TLE4,EZH2,FBXO5,GMNN,ARID4A,ARHGAP6,KIAA0101,CDC6,DCK,MEIS2,SFRS1,WEE1,RANBP1,PCNA,NR3C2,ZNF367,HMGA1,MCM6,MCM4,MCM2,UNG,OSBPL7,HIST1H2BK,E2F7,ATAD2,MELK,POLE2,RAD51,HOXA9;;;;;;;;;;;E2F_Q3_01;0;0;173;33;nucleus (27), protein binding (25), cytoplasm (14)
M10.1;E2F1 targets (Q4);E2F1 targets (Q4) (M10.1);21;TF targets;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M10.1.htm;E2F7,PCNA,NASP,POLE2,SKP2,ERBB2IP,SLBP,POLA2,KNTC1,PKMYT1,MELK,MCM4,PRIM1,FBXO5,RAD51,CIT,STMN1,WEE1,RANBP1,CDC6,DCLRE1A;;;;;;;;;;;E2F1_Q4;0;0;184;21;protein binding (19), nucleus (15), cytoplasm (13)
M11.0;enriched in monocytes (II);enriched in monocytes (II) (M11.0);189;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M11.0.htm;FXYD6,KCNE3,FAM198B,HSPA6,LAT2,CD33,TIMP2,CD36,TNFSF12-TNFSF13,C5AR1,MARCH1,FCGR1B,FCGR1A,SLC15A3,S100A11,MS4A7,MAFB,S100A12,CPPED1,TYROBP,FGR,PLA2G7,IRAK3,LYN,PYGL,SIRPA,FCAR,CRISPLD2,RNASE2,TBXAS1,PLBD1,HK3,FPR2,NOD2,IFI30,AQP9,IMPA2,LRP1,TMEM176A,CSF3R,RBP7,CACNA2D3,MS4A4A,HPSE,KCTD12,SMPDL3A,LST1,RBM47,SYK,SECTM1,PLXDC2,TLR2,CD163,BST1,TLR4,GLT1D1,TREM1,TLR8,FBP1,TNFSF13,CD1D,CSF2RA,SLC7A7,EMR2,RASSF4,SLC31A2,MGST1,IFNGR2,RIN2,LY86,PLXNB2,LILRB3,LILRB2,LILRB1,CLEC7A,QPCT,RNF130,PILRA,NFE2,TNS3,HNMT,GCA,FCN1,TFEC,VNN2,VNN3,TLR5,RTN1,NCF1C,GAS2L1,GRN,BLVRB,ITGAX,MS4A6A,IL13RA1,CD93,TNFAIP2,CD14,ITGAM,SIRPB1,SORT1,AIF1,BTK,NCF2,NCF1,MYCL1,CCR1,CD302,PTAFR,HCK,STAB1,P2RY13,FCER1G,SPI1,CYP1B1,NLRP3,CSF1R,CD86,SCPEP1,ADAP2,S100A9,S100A8,CST3,KIAA0513,EPB41L3,MTMR11,CSTA,RXRA,ASGR1,ASGR2,FES,LGALS2,PRAM1,KIAA1598,CDA,SGK1,LMO2,ALDH2,FGL2,CLEC4E,CTSH,CYFIP1,MPEG1,PLAUR,IGSF6,NLRP12,MEGF9,APOB48R,F13A1,ALDH1A1,SERPINA1,CEBPA,KYNU,RAB32,RAB31,CEBPD,SEPX1,SIGLEC7,SULF2,MYOF,KLF4,FPR1,MNDA,FCGRT,ALOX5,ANPEP,PDGFC,NRGN,PRKCD,FCGR2A,CYBB,PADI2,CPVL,DMXL2,AOAH,CHST15,CFD,SLC11A1,CLEC4A,ZNF467,TYMP,SIGLEC9,LILRA6,TGFBI,LILRA5,LILRA2,LILRA3,CFP,LILRA1;;;;;;;;;;;;;;;;protein binding (104), plasma membrane (72), integral to membrane (62)
M11.1;blood coagulation;blood coagulation (M11.1);22;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M11.1.htm;SLC7A7,AMICA1,CD36,TREM1,P2RX1,F13A1,PECAM1,FCER1G,DOK2,PLAUR,LYN,SIRPA,SERPINA1,GNB4,SERPINB2,ITGAX,F5,SYK,SLC16A3,PSAP,ITGAM,CFD;;;;;;;;;;;;;;;;blood coagulation (20), plasma membrane (16), protein binding (13)
M11.2;formyl peptide receptor mediated neutrophil response;formyl peptide receptor mediated neutrophil response (M11.2);10;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M11.2.htm;NCF2,SLC11A1,CAMK1,FPR1,IGSF6,SECTM1,FCGR2A,PILRA,NCF1C,PAK1;BIOCARTA_FMLP_PATHWAY;0;0;37;5;;;;;;;;;;;protein binding (6), plasma membrane (6), signal transduction (4)
M12;CD28 costimulation;CD28 costimulation (M12);10;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M12.htm;CD28,CHST15,LIME1,SH2D1A,TRAT1,CD24,GRAP2,THEM4,LAT /// SPNS1,LCK;KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;108;3;;;;;;AML_Q6;0;0;204;3;plasma membrane (5), protein binding (4), cytosol (4)
M13;innate activation by cytosolic DNA sensing;innate activation by cytosolic DNA sensing (M13);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M13.htm;DDX58,IRF7,CCL4,CCL5,ZBP1,NFKBIA,AIM2,IL6,PYCARD,CXCL10,IL1B;KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY;0;0;56;11;[Chaussabel.v2]M3.4;0;0;53;4;IRF1_01;0;0;195;4;protein binding (7), cytoplasm (7), inflammatory response (6)
M14;T cell differentiation;T cell differentiation (M14);12;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M14.htm;UBASH3A,TCF7,CD28,TXK,ITK,NOG,LRRN3,BCL11B,RASGRP1,SPOCK2,SH2D1A,MAL;KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;108;3;[Chaussabel.v2]M4.1;0;0;58;7;ER_Q6_01;0;0;203;4;protein binding (11), plasma membrane (4), cytosol (4)
M15;Ran mediated mitosis;Ran mediated mitosis (M15);13;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M15.htm;TPX2,BUB1B,PLK1,H2AFX,KIF15,RAN,ESPL1,AURKA,AURKB,UBE2S,RANBP1,KIF2C,KPNA2;BIOCARTA_RANMS_PATHWAY;0;0;10;6;;;;;;;;;;;protein binding (11), nucleus (11), cytoplasm (11)
M16;TLR and inflammatory signaling;TLR and inflammatory signaling (M16);45;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M16.htm;FCGR1A /// FCGR1C,HSPA6,NCF4,TLR6,C5AR1,FCGR1B,APOB48R,LILRB3,KCNJ15,LILRB1,PILRA,TYROBP,MGAM,FGR,P2RY13,CXCR2,NFE2,IRAK3,MYD88,FPR2,SIGLEC9,FCAR,DYSF,NPL,FPR1,ALOX5,FCGR2C,AQP9,FES,CSF3R,TLR7,LY96,LILRB2,ITGAX,KCNJ2,WDFY3,TLR2,TLR1,BST1,ANPEP,TLR4,TLR5,LILRA6,TLR8,PADI4;;;;;;[Chaussabel.v2]M3.2;0;0;138;12;;;;;;protein binding (29), plasma membrane (29), receptor activity (20)
M17.0;Hox cluster I;Hox cluster I (M17.0);16;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M17.0.htm;CPNE8,HOXB9,LOC404266,HOXB2,HOXB6,HOXB4,HOXA10,HOXA7,HOXA5,HOXA4,HOXA3,MEIS1,NKX2-3,ZNF503,ITGA7,C10orf140;;;;;;;;;;;CDPCR1_01;0;0;99;6;nucleus (13), regulation of transcription, DNA-dependent (12), protein binding (12)
M17.1;Hox cluster II;Hox cluster II (M17.1);12;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M17.1.htm;PRDM16,PDGFD,HOXB3,HOXB6,HOXB7,HOXA11,HOXB5,HOXA5,HOXA4,HOXA3,TTR,LOC404266;;;;;;;;;;;CART1_01;0;0;171;8;protein binding (10), sequence-specific DNA binding (9), nucleus (9)
M17.2;Hox cluster III;Hox cluster III (M17.2);12;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M17.2.htm;HOXB3,HOXB6,HOXB7,HOXA11,HOXA10,HOXA7,MEIS1,HOXA5,HOXA4,HOXB4,MEIS2,HOXA9;;;;;;;;;;;POU6F1_01;0;0;185;8;sequence-specific DNA binding transcription factor activity (12), sequence-specific DNA binding (12), regulation of transcription, DNA-dependent (12)
M17.3;Hox cluster IV;Hox cluster IV (M17.3);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M17.3.htm;HOXB9,HOXB2,HOXB6,HOXB7,HOXB4,HOXB5,HOXA5,HOXA4,HOXA11,HOXA9;;;;;;;;;;;GFI1_01;0;0;243;6;sequence-specific DNA binding transcription factor activity (10), sequence-specific DNA binding (10), regulation of transcription, DNA-dependent (10)
M18;T cell differentiation via ITK and PKC;T cell differentiation via ITK and PKC (M18);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M18.htm;SIRPG,PRKCH,ITK,SH2D1A,ITM2A,ETS1,FASLG,SPOCK2,PRKCQ,ABLIM1,BCL2;BIOCARTA_KERATINOCYTE_PATHWAY;0;0;46;5;[Chaussabel.v2]M4.15;0;0;42;6;AP4_Q6;0;0;173;3;protein binding (11), plasma membrane (5), cytoplasm (5)
M19;T cell differentiation (Th2);T cell differentiation (Th2) (M19);17;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M19.htm;UBASH3A,CD28,LCK,TRAT1,PKIA,HNRPLL,GZMK,LAT,ITM2A,GRAP2,IL32,GPR171,SIT1,DPP4,GATA3,MAL,CD3G;KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;108;5;;;;;;;;;;;protein binding (10), plasma membrane (8), membrane raft (5)
M20;AP-1 transcription factor network;AP-1 transcription factor network (M20);15;TF targets;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M20.htm;CCL2,MMP9,JUNB,FOS,IFNG,FOSB,EGR1,JUN,PLAU,IL6,FOSL1,IL8,FOSL2,ATF3,MMP1;[PID]AP-1 transcription factor network;0;0;66;15;;;;;;SRF_01;0;0;47;5;protein binding (11), regulation of transcription, DNA-dependent (9), sequence-specific DNA binding transcription factor activity (8)
M21;cell adhesion (lymphocyte homing);cell adhesion (lymphocyte homing) (M21);10;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M21.htm;SELL,SDK2,PTK2,CD72,MLLT4,CD24,VAV1,IL32,CCR7,CXCL13;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;4;;;;;;;;;;;protein binding (6), plasma membrane (6), cell adhesion (5)
M22.0;mismatch repair (I);mismatch repair (I) (M22.0);27;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M22.0.htm;SMC1A,POLA1,NCAPG2,RFC5,RFC4,MSH2,TMPO,MSH6,RFC2,GMNN,BUB1,RMI1,RACGAP1,EXO1,POLD3,PRIM1,ZWINT,CHEK1,PCNA,CENPK,FIGNL1,MCM6,RFC3,SSBP1,TOPBP1,RPA3,SMC2;KEGG_MISMATCH_REPAIR;0;0;23;11;;;;;;E2F_Q6;0;0;171;7;nucleus (25), protein binding (24), mitotic cell cycle (15)
M22.1;mismatch repair (II);mismatch repair (II) (M22.1);13;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M22.1.htm;PCNA,RFC3,RFC5,RFC4,MSH2,EXO1,RPA1,MSH6,RFC2,POLD1,POLD3,MLH1,RPA3;KEGG_MISMATCH_REPAIR;1;0;23;13;;;;;;E2F1DP2_01;0;0;127;4;protein binding (13), nucleus (13), DNA repair (13)
M23;RA, WNT, CSF receptors network (monocyte);RA, WNT, CSF receptors network (monocyte) (M23);12;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M23.htm;RARA,FZD1,CEBPA,CSF2RA,FOS,CSF1R,FZD2,RXRA,SPI1,PTGS2,CSF3R,IL8;[PID]Calcineurin-regulated NFAT-dependent transcription in lymphocytes;0;0;42;3;[Chaussabel.v2]M4.13;0;0;79;3;;;;;;protein binding (12), positive regulation of transcription, DNA-dependent (7), nucleus (6)
M24;cell activation (IL15, IL23, TNF);cell activation (IL15, IL23, TNF) (M24);15;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M24.htm;SBNO2,MAP3K8,IL23A,FN1,CD83,PDGFRA,IL15,TNFAIP3,SERPING1,TNF,TF,COL3A1,NFKB2,A2M,BCL3;;;;;;;;;;;NFKAPPAB_01;0;0;194;6;protein binding (14), extracellular region (8), signal transduction (6)
M25;TLR8-BAFF network;TLR8-BAFF network (M25);10;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M25.htm;SLC40A1,TNFSF13B,ASGR1,ASGR2,PCTP,AP1S2,TLR8,BCL6,IL1R2,TBXAS1;;;;;;;;;;;CEBP_Q2_01;0;0;211;10;protein binding (7), membrane (6), integral to membrane (6)
M26.0;TBA;TBA (M26.0);30;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M26.0.htm;TRIM15,CDH17,CDX1,CDX2,MYO1A,FABP1,MUC3B,CRABP2,SLC39A5,VIL1,USH1C,IL22RA1,CLRN3,HMGCS2,GUCY2C,TINAG,DDC,GIPC2,EPS8L3,PPP1R14D,LGALS4,LRRC19,HNF4G,HNF4A,CDHR5,A1CF,NR1I2,RNF128,GPA33,CCL14-CCL15 /// CCL15;;;;;;;;;;;;;;;;protein binding (18), cytoplasm (12), nucleus (8)
M26.1;TBA;TBA (M26.1);22;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M26.1.htm;TRIM15,UGT2A3,CYP3A4,TM4SF5,VIL1,USH1C,CLRN3,TINAG,DDC,CYP3A7,GIPC2,CYP3A5,LGALS4,ARSE,LRRC19,HNF4G,RNF186,HNF4A,CDHR5,RNF128,A1CF,CCL14-CCL15 /// CCL15;;;;;;;;;;;;;;;;protein binding (10), membrane (10), metal ion binding (9)
M26.2;TBA;TBA (M26.2);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M26.2.htm;TRIM15,LRRC19,HNF4G,HNF4A,VIL1,CLRN3,FOXA3,RNF128,DDC,USH1C,CLDN2,A1CF,CCL14-CCL15 /// CCL15,LGALS4;;;;;;;;;;;FOXM1_01;0;0;187;4;protein binding (8), cytoplasm (6), zinc ion binding (4)
M27.0;chemokine cluster (I);chemokine cluster (I) (M27.0);26;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M27.0.htm;CCL2,CCL1,CCL7,CCL4,CCL5,CCL8,PF4,XCL1,PPBP,CCL20,CCL23,IFNG,CXCL2,CXCL11,CXCL10,CXCL13,CXCL12,CXCL1,CXCL3,CCL13,CXCL5,CXCL6,CCL18,CCL19,CXCL9,IL8;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;25;;;;;;NFKAPPAB_01;0;0;194;7;immune response (26), extracellular space (26), extracellular region (26)
M27.1;chemokine cluster (II);chemokine cluster (II) (M27.1);15;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M27.1.htm;ANXA1,CCL2,CXCL5,CCL7,CCL4,CCL5,CXCL9,CXCL6,CCR1,XCL1,CCR5,CXCL10,CXCL11,CCL20,CXCL13;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;14;;;;;;NFKAPPAB_01;0;0;194;6;immune response (14), chemotaxis (14), extracellular space (13)
M28;antigen presentation (lipids and proteins);antigen presentation (lipids and proteins) (M28);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M28.htm;CD1D,CD1E,CD1B,CD1C,CD1A,HLA-DRB1,HLA-DRA,CD36,HLA-DRB4,CCR7,CD8A;KEGG_HEMATOPOIETIC_CELL_LINEAGE;0;0;88;10;;;;;;;;;;;plasma membrane (10), protein binding (9), immune response (9)
M29;proinflammatory cytokines and chemokines;proinflammatory cytokines and chemokines (M29);10;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M29.htm;PTX3,CCRL2,IL6,CCL3 /// CCL3L1 /// CCL3L3,TNF,IL1A,C3,CCL20,IL1B,IL8;BIOCARTA_LAIR_PATHWAY;0;0;17;5;;;;;;CEBPB_01;0;0;203;3;inflammatory response (9), extracellular region (8), protein binding (7)
M30;cell movement, Adhesion & Platelet activation;cell movement, Adhesion & Platelet activation (M30);20;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M30.htm;PDGFA,ITGB3,PTK2,TNS1,SELP,MPP1,PROS1,KIF26A,TPM1,GAB1,NAV1,HBEGF,CTGF,COL5A1,ALOX12,ESAM,GP6,CALD1,CD9,SEMA6A;;;;;;[Chaussabel.v2]M1.1;0;0;86;5;;;;;;protein binding (15), plasma membrane (9), cytoplasm (8)
M31;cell cycle and growth arrest;cell cycle and growth arrest (M31);12;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M31.htm;RARA,SIK1,GADD45B,JUNB,TNFAIP3,THBS1,PPP1R15A,OSM,IL1A,IL1B,DUSP1,IL8;BIOCARTA_NTHI_PATHWAY;0;0;24;3;;;;;;SRF_C;0;0;175;3;protein binding (11), apoptosis (7), nucleus (5)
M32.0;platelet activation (I);platelet activation (I) (M32.0);23;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.0.htm;TGFB1,PPP2R1A,CCDC22,AKT1,CORO1A,GNAI2,ZYX,H1FX,POR,TLN1,APEH,FAM108A1,NR1H2,ACAP1,GNB2,HGS,NUCB1,UBE2M,PPP1CA,ACTN4,PFN1,FLNA,NRBP1;KEGG_FOCAL_ADHESION;0;0;201;6;;;;;;;;;;;protein binding (17), cytoplasm (17), nucleus (11)
M32.1;platelet activation (II);platelet activation (II) (M32.1);21;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.1.htm;TGFB1,EHMT2,TLN1,ACTN4,PKN1,SIPA1,ACAP1,GNB2,AP2M1,AKT1,MAP7D1,MLF2,ZYX,NBEAL2,DNM2,FLNA,HGS,PFN1,GNAI2,MAP2K2,PNPLA6;;;;;;;;;;;;;;;;protein binding (19), cytoplasm (15), nucleus (12)
M32.2;CORO1A-DEF6 network (I);CORO1A-DEF6 network (I) (M32.2);20;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.2.htm;TGFB1,AES,FAM108A1,UBE2M,DEF6,H1FX,CCDC22,ACAP1,TECR,HGS,SIPA1,CORO1A,CLPTM1,TSC2,SH2B1,APEH,CBX4,STXBP2,BRD2,ATP5D;;;;;;;;;;;EGR_Q6;0;0;212;7;protein binding (13), cytoplasm (12), nucleus (9)
M32.3;KLF12 targets network;KLF12 targets network (M32.3);17;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.3.htm;DGKZ,NRBP1,LTBP3,NR1H2,PPP2R1A,RHOG,POR,ACAP1,GNB2,CORO1A,CLPTM1,CNOT3,UBE2M,HGS,FAM108A1,GNAI2,NBEAL2;;;;;;;;;;;;;;;;protein binding (14), cytoplasm (9), plasma membrane (5)
M32.4;CORO1A-DEF6 network (II);CORO1A-DEF6 network (II) (M32.4);15;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.4.htm;DGKZ,NRBP1,MAZ,UBE2M,DEF6,H1FX,ACAP1,GNB2,CORO1A,NR1H2,SH2B1,CNOT3,HGS,FAM108A1,BRD2;;;;;;;;;;;ALPHACP1_01;0;0;189;5;protein binding (13), cytoplasm (10), nucleus (8)
M32.5;TBA;TBA (M32.5);15;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.5.htm;PPP2R1A,AES,MAZ,UBE2M,ASNA1,RALY,PKN1,ACIN1,AP2M1,MLF2,NRBP1,DNM2,PPP1R9B,NUCB1,HMG20B;;;;;;;;;;;E2F_Q6_01;0;0;170;4;protein binding (11), nucleus (10), cytoplasm (8)
M32.6;TBA;TBA (M32.6);13;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.6.htm;PPP2R1A,MLF2,TGFB1,PKN1,CPNE1,HGS,PSMD3,CDC37,AP2M1,AKT1,DNM2,NUCB1,HMG20B;;;;;;;;;;;STAT_01;0;0;199;4;protein binding (12), cytoplasm (9), nucleus (7)
M32.7;TBA;TBA (M32.7);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.7.htm;AES,STK11,UBE2M,EIF4G1,H1FX,HGS,MAP2K2,MAP7D1,DCAF15,TSC2,BRD2;;;;;;;;;;;EGR_Q6;0;0;212;3;protein binding (8), cytoplasm (6), nucleus (5)
M32.8;cytoskeletal remodeling;cytoskeletal remodeling (M32.8);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M32.8.htm;TGFB1,ATP2A3,SPTAN1,ACIN1,TLN1,AP2M1,AKT1,MAP7D1,FLNA,ZYX;KEGG_FOCAL_ADHESION;0;0;201;4;;;;;;CRGAARNNNNCGA_UNKNOWN;0;0;36;3;protein binding (9), cytoplasm (8), nucleus (6)
M33;inflammatory response;inflammatory response (M33);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M33.htm;TBC1D8,TNFSF13,FCER1G,STAB1,TYROBP,GPX1,CARD9,ARRB2,TLR4,APOB48R,AIF1;;;;;;;;;;;ELF1_Q6;0;0;182;11;protein binding (8), plasma membrane (5), cytoplasm (5)
M34;cytoskeletal remodeling (enriched for SRF targets);cytoskeletal remodeling (enriched for SRF targets) (M34);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M34.htm;ACTN1,PPAP2B,VCL,MYLK,TPM1,NR2F2,CTGF,THBS1,CALD1,TPM2;KEGG_FOCAL_ADHESION;0;0;201;4;;;;;;SRF_Q4;0;0;191;10;protein binding (8), cytosol (7), muscle contraction (5)
M35.0;signaling in T cells (I);signaling in T cells (I) (M35.0);14;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M35.0.htm;IL2RA,JUNB,GZMB,FOS,IFNG,FOSB,EGR1,JUN,TNF,FASLG,PRF1,TNFRSF4,ATF3,TNFRSF9;"[PID]Downstream signaling in naïve CD8+ T cells";0;0;29;12;;;;;;SRF_01;0;0;47;4;protein binding (11), regulation of transcription, DNA-dependent (7), nucleus (7)
M35.1;signaling in T cells (II);signaling in T cells (II) (M35.1);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M35.1.htm;IL2RA,IL2RB,GZMB,IFNG,TNF,FOSL1,PRF1,TNFRSF4,FASLG,TNFRSF18,TNFRSF9;"[PID]Downstream signaling in naïve CD8+ T cells";0;0;29;11;[Chaussabel.v2]M3.6;0;0;47;4;NFKAPPAB_01;0;0;194;3;protein binding (9), plasma membrane (7), external side of plasma membrane (7)
M36;T cell surface, activation;T cell surface, activation (M36);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M36.htm;CXADR,LILRB4,CD40LG,LILRB2,LILRB1,TYROBP,ITGA4,VCAM1,CD8A,LILRB3,CD3D,CD3E;KEGG_PRIMARY_IMMUNODEFICIENCY;0;0;35;4;;;;;;;;;;;protein binding (12), plasma membrane (11), regulation of immune response (10)
M37.0;immune activation - generic cluster;immune activation - generic cluster (M37.0);347;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M37.0.htm;ELANE,SAMD13,CAMK4,GPR109B,BANK1,DYSF,MACROD2,MS4A4A,PRRG4,ORM1,C19orf59,ERI2,LAT,PPIL4,CSRP2,MAL,CD1B,RASGRP4,MGST1,PRG2,VPREB1,VPREB3,ENG,GRAP2,NCAPD2,NCAPD3,BLM,TCN1,SLC22A4,ANPEP,SIRPB1,CD19,RETN,MBOAT2,CLEC5A,PLA2G7,CIITA,PTX3,SMC4,P2RY13,S100A8,RNF150,KIAA0513,C10orf10,MANSC1,LTF,PRAM1,SLC27A2,ACPP,F5,HMGB2,CHAF1A,CHAF1B,HLA-DRA,SULF2,CDK14,CXCR2,KLF5,DEFA4,DEFA1,JAG1,FPR2,SLC24A4,CTSG,TCL1A,C3AR1,NUP37,CA4,OGN,CMTM2,LILRA5,LILRA3,LIN7A,HNRPLL,DKFZp451A211,MARCH1,CHI3L2,CHI3L1,CYP4F2,CYP4F3,B3GNT5,ORC6L,ROPN1L,CRISPLD2,CENPL,CRISP3,BARD1,FAM69B,CCDC150,RBBP8,LY96,ACCN2,GH1,AZU1,DBF4,CD300C,LOC90925,EMR1,VANGL1,ARHGEF10L,OSCAR,MGAM,CCNE1,CEACAM1,CEACAM6,TACSTD2,BMX,PLXDC2,G0S2,JAM3,VNN2,VNN1,IGFBP7,BLVRB,GALNT6,STK32B,C15orf23,MEF2C,DTYMK,GPR97,BTK,CD72,CXorf50B,RFC2,PRKAR2B,TREM1,MCTP1,GAS2L1,NLRP3,ADAP2,RANBP1,FGD4,ACPL2,LOC81691,CLC,GXYLT2,UNG,GAB1,TM6SF1,FAM43A,LOC284757,SLC22A15,BASP1,PTK2,SVIL,LCN2,BPI,MSH2,MEGF9,F13A1,VSTM1,IQGAP3,ARAP3,RAD54B,C13orf34,RGL1,CAMP,RGL4,LOC100130458,ST3GAL6,FCGR2C,MGC5566,PADI2,EBF1,DHCR24,CLEC4D,PFKFB4,ZNF467,TUBG1,MOSC1,MMP8,MMP9,SAC3D1,FKBP14,PTGS2,AMICA1,LOC643332,CLEC14A,TXNDC3,FAM46A,PSD3,INHBA,PRTN3,FCAR,BRCA2,HAL,LRRC4,CREB5,AQP9,TMEM176A,TMEM176B,CTSS,CXCL1,PSRC1,SMPDL3A,ADCY9,RUNX2,BST1,PID1,CD3E,CD3G,CSF2RB,MARCH3,DOCK5,LARGE,TSHR,ICOSLG,QPCT,JUP,NFE2,PAX5,CORO2A,CR1,PROK2,PEX5L,PRTFDC1,LOC100289612,SH2D1A,CD177,CD7,CD2,OLFM4,CCR9,CD9,SLC8A1,GPR84,KIF16B,ABCA13,LGALS3,BCL11B,RAD51C,SLPI,LRP1,CDA,SGK1,STX11,HLA-DOA,AGPAT9,CYFIP1,CDKN2C,FCGR3A,S100P,FCGR3B,FOXO1,NLRC4,ALDH1A1,MLLT4,CHIT1,SLCO4C1,LOC728606,LPCAT2,HK3,ITGAM,ANXA3,ANXA5,NRGN,MCM7,MCM3,IL18RAP,UPP1,SAMHD1,CEBPE,OLR1,IMPA2,KCNK5,CKAP2,BCL6,KCNE3,LAT2,PKMYT1,FBP1,MS4A7,MS4A3,GSN,VSIG10,NDST3,LYZ,NAV1,LYN,MYB,PYGL,RNASE3,RNASE2,ENTPD1,RNASE6,CD22,TSPAN2,RBP7,CACNA2D3,ACSL1,TLR1,TLR7,ATP8B4,SLC19A2,GGTA1,CLEC12A,HP,GPBAR1,IL1R2,FLJ10357,BEX1,LRRK2,SCD,PCBP3,SERPINB10,TLR5,RHOU,SLC26A8,ARG1,TNFAIP6,ELOVL4,FAM105A,FAM150B,NCF4,GAS2L3,GNAI1,LGALS12,SLA2,C11orf75,DUSP6,FAM49A,EMILIN2,CTGF,CSE1L,STEAP4,MYCL1,TFF3,APOB48R,UBASH3A,RAB32,ESCO2,TRAT1,DOK3,IL1R1,NACC2,LRP12,PDGFC,KCNJ15,DACH1,LRG1,ACTN1,SLC40A1,SIGLEC9,SIGLEC5,FOLR3,ZNF608,MYO7B;;;;;;;;;;;;;;;;protein binding (183), plasma membrane (99), integral to membrane (99)
M37.1;enriched in neutrophils (I);enriched in neutrophils (I) (M37.1);52;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M37.1.htm;LIN7A,NCF4,EMR3,FCGR3A,S100P,FCGR3B,TNFRSF10C,C5AR1,MGC31957,CHI3L1,NLRP12,CYP4F3,MXD1,SEPX1,MGAM,DGAT2,RGL4,REPS2,VNN2,CXCR1,NFE2,KRT23,GPR109B,PYGL,FPR2,G0S2,KCNJ15,LRRC4,FPR1,CREB5,FCGR2A,CMTM2,MANSC1,CSF3R,FFAR2,RNF24,LRG1,ST6GALNAC2,ORM1,MME,CDA,PROK2,PFKFB4,VNN3,SLC22A4,BASP1,TREM1,GLT1D1,GPR97,PTAFR,STEAP4,ALPL;;;;;;[Chaussabel.v2]M3.2;0;0;138;22;;;;;;plasma membrane (25), integral to membrane (23), protein binding (19)
M37.2;endoplasmic reticulum;endoplasmic reticulum (M37.2);19;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M37.2.htm;TMED6,WFS1,TBXAS1,SGK1,SCD,UNC93B1,ACSL1,CD4,FAM69B,ELOVL4,MGST1,LPCAT2,TLR7,SORT1,MARCH1,CYP4F2,CYP4F3,TLR8,DHCR24;;;;;;;;;;;;;;;;integral to membrane (17), endoplasmic reticulum membrane (16), endoplasmic reticulum (16)
M37.3;cell division;cell division (M37.3);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M37.3.htm;SAC3D1,RBBP8,RUVBL1,CCNE1,NUP37,NCAPD3,BLM,NCAPD2,CKAP2,VRK1;;;;;;;;;;;;;;;;protein binding (9), nucleus (8), cytoplasm (7)
M38;chemokines and receptors;chemokines and receptors (M38);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M38.htm;CCL2,CCL4,CCL5,DOCK2,TNF,CXCR6,ICAM1,CXCR4,HCK,IL8,CCR5;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;9;;;;;;;;;;;protein binding (8), inflammatory response (7), immune response (6)
M39;integrin mediated leukocyte migration;integrin mediated leukocyte migration (M39);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M39.htm;ITGB2,TXK,ITK,VAV1,PIK3CD,PRKCB,ITGA4,PLCG1,ITGAL,VCAM1;KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION;0;0;118;10;;;;;;ELF1_Q6;0;0;182;3;protein binding (10), plasma membrane (9), blood coagulation (6)
M40;complement and other receptors in DCs;complement and other receptors in DCs (M40);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M40.htm;ITGAX,SIRPA,OLR1,TYROBP,CD58,C1QC,C1QB,C1QA,CD86,HLA-DQB1,LY96,TLR8,HLA-DQA1;KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS;0;0;140;6;;;;;;;;;;;protein binding (12), plasma membrane (9), membrane (5)
M41.0;TBA;TBA (M41.0);17;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M41.0.htm;MAGEA12,SLC7A11,OBSL1,PLUNC,TUBB4,CA14,SPRY4,AFF2,SLC17A1,HOXC11,HOXC10,DEFA5,CEACAM7,HIST1H3E,REEP1,PEG3,IFNA14;;;;;;;;;;;LEF1_Q6;0;0;219;5;protein binding (9), integral to membrane (5), plasma membrane (4)
M41.1;TBA;TBA (M41.1);15;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M41.1.htm;MAGEA12,DMD,PRO2012,ERBB4,SPINLW1,DAAM2,SLC17A1,HOXC10,DEFA5,PEG3,ADCYAP1,MTMR8,CYP11B1,IFNA14,ATP7B;;;;;;;;;;;CREBP1_Q2;0;0;189;4;protein binding (5), nucleus (4), extracellular region (4)
M41.2;TBA;TBA (M41.2);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M41.2.htm;MAGEA12,OBSL1,ADCYAP1,ERBB4,GRID2,TUBB4,SLC7A11,POU4F2,SLC17A1,DEFA5,GFRA3,MTMR8,PEG3,IFNA14;;;;;;;;;;;SREBP_Q3;0;0;186;5;protein binding (8), plasma membrane (5), receptor activity (3)
M41.3;TBA;TBA (M41.3);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M41.3.htm;EPHB1,DMD,PRO2012,ERBB4,TFAP2A,HOXC10,DEFA5,NPR3,CYP11B1,PEG3;;;;;;;;;;;E2F1DP1RB_01;0;0;175;5;protein binding (5), regulation of transcription, DNA-dependent (4), nucleus (4)
M41.4;ATF targets network;ATF targets network (M41.4);10;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M41.4.htm;SULT4A1,HOXC10,DAAM2,SPINLW1,FABP7,ADCYAP1,HIST1H3E,REEP1,PEG3,ATP7B;;;;;;;;;;;ATF_01;0;0;208;5;cytoplasm (4), protein binding (3), nucleus (3)
M42;platelet activation (III);platelet activation (III) (M42);10;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M42.htm;FCER1G,GNAQ,SYK,VAV1,PLCG2,PIK3R5,GNA15,COL1A1,LCP2,LYN;KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY;0;0;79;7;;;;;;ETS_Q4;0;0;180;3;platelet activation (10), blood coagulation (10), protein binding (8)
M43.0;myeloid, dendritic cell activation via NFkB (I);myeloid, dendritic cell activation via NFkB (I) (M43.0);15;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M43.0.htm;MAP3K8,IL23A,CCL5,CD83,NFKBID,FUT7,CTGF,TNF,VCAM1,ICAM1,SAMSN1,RELB,NFKB2,EBI3,BCL3;;;;;;;;;;;NFKAPPAB_01;0;0;194;14;protein binding (13), plasma membrane (6), extracellular space (6)
M43.1;myeloid, dendritic cell activation via NFkB (II);myeloid, dendritic cell activation via NFkB (II) (M43.1);14;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M43.1.htm;IL1RN,IL23A,CCL5,NFKBIA,BIRC3,PRKCD,FUT7,LTB,TNIP3,ICAM1,RELB,NFKB2,EBI3,BCL3;;;;;;;;;;;NFKB_Q6_01;0;0;176;14;protein binding (11), nucleus (7), cytoplasm (7)
M44;T cell signaling and costimulation;T cell signaling and costimulation (M44);10;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M44.htm;IL7R,TCF7,IL23A,FYN,IFI30,CD37,MAPK14,ARHGDIB,LCP1,LCK;BIOCARTA_IL7_PATHWAY;0;0;17;3;;;;;;ELK1_01;0;0;191;10;protein binding (8), plasma membrane (5), cytosol (5)
M45;leukocyte activation and migration;leukocyte activation and migration (M45);11;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M45.htm;SIRPG,FCER1G,INPP5D,CD48,FYN,ITGA4,SELPLG,PTPN6,ITGAL,CD2,LCK;KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY;0;0;137;6;[Chaussabel.v2]M4.15;0;0;42;3;;;;;;protein binding (11), leukocyte migration (11), blood coagulation (11)
M46;cell division stimulated CD4+ T cells;cell division in stimulated CD4+ T cells (M46);28;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M46.htm;DHCR24,DTL,ZWINT,RRM2,KIAA0101,TST,TYMS,CDT1,KIF4A,CDCA3,CDCA7,MYB,GGH,TOP2A,CDK6,GNB4,LOC81691,UHRF1,SLC27A2,ACTN1,GINS1,ZNRF1,SHCBP1,APOBEC3B,CDK1,RAD51,CDC45,KIF20A;;;;;;[Chaussabel.v2]M3.3;0;0;49;9;;;;;;protein binding (18), nucleus (16), cytoplasm (14)
M47.0;enriched in B cells (I);enriched in B cells (I) (M47.0);53;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M47.0.htm;STAP1,BLK,CD72,TSPAN13,BCL11A,C13orf18,KIAA0125,CD200,CD79B,VPREB3,CD79A,P2RX5,BTLA,AFF3,PPAPDC1B,IGHM,LOC90925,FCRLA,SPIB,FAM129C,ABCB4,LOC100130458,FCRL1,BANK1,MS4A1,FCRL5,TCF4,KLHL14,CXCR5,PCDH9,RALGPS2,CD22,TCL1A,CD24,IGH@,IGKV3-20,IGHD,MACROD2,EBF1,PNOC,ADAM28,LOC283663,CR2,PAX5,E2F5,PLEKHG1,FCER2,PKIG,FCRL2,IGLJ3,HLA-DOB,PTPRK,CD19;;;;;;[Chaussabel.v2]M4.10;0;0;32;23;;;;;;protein binding (32), plasma membrane (21), integral to membrane (15)
M47.1;enriched in B cells (II);enriched in B cells (II) (M47.1);43;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M47.1.htm;LOC90925,IGHA1,BCL11A,LOC642838,KIAA0125,LOC642424,IGK@,CD79B,CD79A,TPD52,CDK14,CXCR5,BANK1,MS4A1,FCRL5,BLNK,TCF4,SP140,KLHL14,RALGPS2,FCRLA,FCGR2B,TCL1A,CELSR1,CD24,IGH@,DENND5B,EBF1,PNOC,PAWR,CD180,IGHM,CR2,PAX5,LOC100130100,PLEKHG1,POU2AF1,PKIG,FAM30A,HLA-DOB,KLF8,PTPRK,CD19;;;;;;[Chaussabel.v2]M4.10;0;0;32;13;;;;;;protein binding (28), plasma membrane (17), integral to membrane (12)
M47.2;enriched in B cells (III);enriched in B cells (III) (M47.2);37;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M47.2.htm;LOC90925,LOC652493,IGHA1,LOC642838,KIAA0125,LOC642424,IGK@,IGKC,VPREB3,MEF2C,TPD52,LOC284749,CDK14,FCRL3,FCRL5,HHEX,TBC1D9,FCRLA,ALOX5,FCGR2B,CELSR1,CD24,IGH@,IGHD,CD69,PNOC,PAWR,CD180,FAIM3,LOC100130100,IGLV1-44,FAM30A,IGL@,HLA-DOA,HLA-DQA1,BTK,DENND5B;;;;;;;;;;;;;;;;protein binding (21), plasma membrane (10), integral to membrane (8)
M47.3;enriched in B cells (IV);enriched in B cells (IV) (M47.3);16;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M47.3.htm;FAIM3,LOC284749,CPNE5,TPD52,CIITA,IGHA1,TLR10,IGHG1,CELSR1,FAM30A,CDK14,PAWR,CD180,MEF2C,BTK,HLA-DOA;;;;;;;;;;;;;;;;protein binding (13), plasma membrane (7), nucleus (5)
M47.4;enriched in B cells (V);enriched in B cells (V) (M47.4);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M47.4.htm;GPR18,FAIM3,FCRL3,FCGR2B,LY9,CELSR1,CD37,TLR10,CD69,CD180,FCRL5;;;;;;;;;;;;;;;;integral to membrane (10), protein binding (7), plasma membrane (7)
M48;TBA;TBA (M48);13;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M48.htm;TNFSF13,PLCB2,HHEX,STAB1,TYROBP,SH3TC1,KCNQ1,DOK2,SPI1,PTAFR,TLR4,APOB48R,LYN;;;;;;;;;;;ELF1_Q6;0;0;182;6;protein binding (10), signal transduction (6), plasma membrane (5)
M49;transcription regulation in cell development;transcription regulation in cell development (M49);47;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M49.htm;MYH10,STMN1,TIMP2,HMGB2,MSH2,SPTB,EPB42,SPTA1,PLCG1,FBXO5,HBZ,SEMA4A,GSN,PLXNB2,CEBPA,TYMS,ECT2,ANK1,TAL1,ASPM,KIF4A,FHL2,KLF4,KLF1,CDH1,LYN,BRCA1,ARHGEF12,SOD2,VCAN,RXRA,FES,CASC5,ACHE,TRIP13,C11orf82,GATA1,CCNB1,LILRB1,LST1,SDC2,TMOD1,CDC20,CDK1,BASP1,TYROBP,PAK1;;;;;;;;;;;;;;;;protein binding (41), cytoplasm (25), nucleus (22)
M50;CD1 and other DC receptors;CD1 and other DC receptors (M50);10;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M50.htm;CD1E,CD1B,CD1C,CD1A,CSF1R,IL1R2,CSF2RA,ANPEP,CD9,IL1R1;KEGG_HEMATOPOIETIC_CELL_LINEAGE;0;0;88;10;;;;;;;;;;;protein binding (9), plasma membrane (9), integral to plasma membrane (8)
M51;cell adhesion;cell adhesion (M51);38;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M51.htm;CDH11,THBS2,LAMB1,ALOX12,COL3A1,CHL1,LAMA4,ARHGAP6,IL1B,ITGA2B,MMRN1,JAM3,GP1BA,TPM1,THBS1,NID2,GP9,PARVB,ITGB3,ITGB5,ENG,POSTN,COL5A1,VCAM1,TNC,SNAI2,CXCL12,SLAMF7,FN1,CCDC80,SRPX,MGP,ESAM,COL1A1,COL6A1,VWF,SELP,IL8;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;16;;;;;;;;;;;protein binding (29), cell adhesion (26), extracellular region (20)
M52;T cell activation (IV);T cell activation (IV) (M52);13;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M52.htm;SELL,SPI1,GFI1,LPXN,XCL1,GATA3,LAG3,CD5,PTPN6,PTPRC,UNC93B1,LCK,CD3E;;;;;;;;;;;PEA3_Q6;0;0;182;13;protein binding (9), plasma membrane (5), membrane (5)
M53;inflammasome receptors and signaling;inflammasome receptors and signaling (M53);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M53.htm;NLRP3,NFKBIA,BIRC3,BIRC2,TNFAIP3,RXRA,CARD9,RIPK2,TLR4,NOD2,NLRC4,PAK1;KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY;0;0;62;9;[Chaussabel.v2]M6.13;0;0;48;3;;;;;;protein binding (12), cytoplasm (11), regulation of apoptosis (6)
M54;BCR signaling;BCR signaling (M54);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M54.htm;INPP5D,SYK,PIK3CD,VAV1,PLCG2,PIK3R5,PIK3R3,RAC2,LYN,PTPN6,BTK,BLNK;KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;75;12;;;;;;OCT1_Q6;0;0;210;4;protein binding (11), plasma membrane (9), cytosol (9)
M55;TBA;TBA (M55);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M55.htm;RARA,LRP1,RASGRP4,SPI1,GRINA,PRKCD,DOK3,PDLIM7,MBOAT7,CSF3R,RHOG,ZYX;;;;;;;;;;;COUP_DR1_Q6;0;0;183;4;protein binding (9), plasma membrane (7), cytoplasm (7)
M56;suppression of MAPK signaling;suppression of MAPK signaling (M56);12;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M56.htm;HSPA6,RASGRP4,FOS,CD14,ARRB2,ARRB1,CACNA2D3,IL1B,DUSP6,DUSP1,IL1R2,DUSP3;[PID]ErbB1 downstream signaling;0;0;61;3;;;;;;TAXCREB_01;0;0;105;3;protein binding (9), plasma membrane (5), nucleus (5)
M57;immuregulation - monocytes, T and B cells;immuregulation - monocytes, T and B cells (M57);13;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M57.htm;CTLA4,IL23A,CCL4,FCER2,CAMK2D,CSF3,OSM,IGHD,BLK,CD200,IL1A,KIT,CD79A;KEGG_HEMATOPOIETIC_CELL_LINEAGE;0;0;88;4;;;;;;;;;;;protein binding (8), immune response (6), extracellular region (6)
M58;B cell development/activation;B cell development/activation (M58);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M58.htm;TCF4,JAM3,NEDD4,GAB2,PIK3CD,SPIB,BCL2,LYN,DUSP6,BTK,BLNK;KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;75;4;;;;;;OCT1_Q6;0;0;210;11;protein binding (10), cytoplasm (8), plasma membrane (7)
M59;CCR1, 7 and cell signaling;CCR1, 7 and cell signaling (M59);10;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M59.htm;DUSP6,ZNF423,TIMP2,SOCS2,MAPK14,CCR1,CISH,CCR7,BCL6,TRIB1;;;;;;[Chaussabel.v2]M3.2;0;0;138;3;HSF1_01;0;0;202;5;protein binding (9), nucleus (4), cytoplasm (4)
M60;lymphocyte generic cluster;lymphocyte generic cluster (M60);17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M60.htm;MEF2C,CD28,DTX3,GAB1,SH2D2A,ADARB1,LARGE,FAM69B,CTGF,PRKCZ,CHI3L2,CD2,CLIP4,BANK1,DHCR24,NAV1,CD19;;;;;;;;;;;;;;;;protein binding (10), cytoplasm (6), plasma membrane (5)
M61.0;enriched in NK cells (II);enriched in NK cells (II) (M61.0);24;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M61.0.htm;KLRB1,CD7,GPR56,NKG7,KIR2DL2,KIR2DS4,KIR2DS5,KIR2DS2,KIR2DS3,S1PR5,KIR2DS1,KLRF1,TGFBR3,KIR3DL1,KIR2DL5A,KIR3DL3,IL2RB,KLRK1,KIR2DL3,CD96,KIR2DL1,CD247,PVRIG,TARP;KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY;0;0;137;11;[Chaussabel.v2]M3.6;0;0;47;7;;;;;;plasma membrane (16), integral to membrane (13), integral to plasma membrane (12)
M61.1;enriched in NK cells (KIR cluster);enriched in NK cells (KIR cluster) (M61.1);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M61.1.htm;KIR2DS4,KIR2DS5,KIR2DS2,KIR2DS3,KIR2DS1,KIR2DL3,KIR2DL2,KIR2DL1,KIR2DL4,KIR3DS1,KIR3DL1,KIR2DL5A,KIR3DL3;KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION;0;0;89;11;[Chaussabel.v2]M8.46;0;0;16;5;;;;;;plasma membrane (8), regulation of immune response (7), receptor activity (7)
M61.2;enriched in NK cells (receptor activation);enriched in NK cells (receptor activation) (M61.2);16;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M61.2.htm;KIR2DL3,ITK,CD96,CARD11,KIR2DS2,KIR2DS1,CD244,KIR2DL2,KIR2DL1,CD247,KLRK1,ZAP70,KIR2DL4,PRKCQ,KIR3DL1,KLRD1;KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY;0;0;137;11;[Chaussabel.v2]M4.15;0;0;42;5;;;;;;plasma membrane (14), protein binding (12), regulation of immune response (10)
M62.0;T & B cell development, activation;T & B cell development, activation (M62.0);44;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M62.0.htm;FKBP14,PTK2,CD1B,EBF1,CD3G,GAB1,CD7,GPM6B,ICOSLG,VPREB1,CD9,VPREB3,LOC100132741,PSD3,TRAT1,SAMD13,RGL1,SCD,NDST3,ELOVL4,NTRK2,NAV1,LOC100130458,RNF150,UBASH3A,LRP12,ACPL2,CAMK2D,TCL1A,GXYLT2,STK32B,ACCN2,GH1,LOC284757,ADCY9,MAL,VSIG10,CTGF,OGN,FAM150B,SH2D1A,CSRP2,CD3E,HHIP;;;;;;;;;;;;;;;;protein binding (28), plasma membrane (15), membrane (14)
M62.1;enriched for unknown TF motif CTCNANGTGNY;enriched for unknown TF motif CTCNANGTGNY (M62.1);12;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M62.1.htm;TMPRSS3,ACCN2,PTK2,EBF1,ENG,VSIG10,DTX3,MGC5566,ELOVL4,GXYLT2,SMPD3,HHIP;;;;;;;;;;;CTCNANGTGNY_UNKNOWN;0;0;74;5;protein binding (9), integral to membrane (7), membrane (6)
M63;regulation of localization (GO);regulation of localization (GO) (M63);12;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M63.htm;SNX17,TGFB1,ARAP1,AKT1,PKN1,MAP2K2,STXBP2,NAPA,ARHGDIA,FLNA,TSC2,NR1H2;KEGG_RENAL_CELL_CARCINOMA;0;0;70;3;[Chaussabel.v2]M4.16;0;0;97;3;;;;;;protein binding (12), cytoplasm (10), cytosol (9)
M64;enriched in activated dendritic cells/monocytes;enriched in activated dendritic cells/monocytes (M64);17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M64.htm;CXCL1,DRAM1,G0S2,SOD2,SIRPA,IL1RN,NINJ1,IL13RA1,TNFAIP2,SLC31A2,BASP1,MARCKS,FAM129A,ANPEP,SLC15A3,IL1B,IL8;;;;;;[Chaussabel.v2]M3.2;0;0;138;5;;;;;;protein binding (7), plasma membrane (7), integral to membrane (6)
M65;IL2, IL7, TCR network;IL2, IL7, TCR network (M65);12;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M65.htm;IL7R,PTPRCAP,ITK,TRAC,IL2RG,LTB,TRA@ /// TRAC /// TRAJ17 /// TRAV20,TRBC1,JAK3,CCR7,LCK,BCL2;BIOCARTA_IL7_PATHWAY;0;0;17;5;[Chaussabel.v2]M4.1;0;0;58;3;;;;;;protein binding (7), plasma membrane (6), signal transduction (4)
M66;TBA;TBA (M66);17;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M66.htm;FCER1G,IDO1,CYP1B1,KMO,SLC7A7,KIAA1598,HMOX1,KYNU,ALDH2,CYBB,SLC31A2,ADAP2,IFI30,CST3,MAFB,BTK,CPVL;KEGG_TRYPTOPHAN_METABOLISM;0;0;40;5;[Chaussabel.v2]M4.14;0;0;59;8;;;;;;protein binding (8), cytosol (7), oxidoreductase activity (6)
M67;activated dendritic cells;activated dendritic cells (M67);12;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M67.htm;CD38,DDX58,IRF7,PLSCR1,BIRC3,C1QC,IFIH1,SERPING1,DDX60,C2,IGKC,RSAD2;KEGG_COMPLEMENT_AND_COAGULATION_CASCADES;0;0;69;3;[Chaussabel.v2]M3.4;0;0;53;4;;;;;;protein binding (9), innate immune response (7), nucleus (4)
M68;RIG-1 like receptor signaling;RIG-1 like receptor signaling (M68);10;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M68.htm;DDX58,IRF7,DHX58,TRIM25,NFKBIA,IFIH1,TNF,ISG15,CXCL10,IL8;KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY;0;0;71;10;[Chaussabel.v2]M3.4;0;0;53;4;;;;;;protein binding (9), cytoplasm (7), innate immune response (6)
M69;enriched in B cells (VI);enriched in B cells (VI) (M69);20;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M69.htm;CR2,PCDH9,TSPAN13,HLA-DOB,CD72,PTPRK,CD22,P2RX5,BTLA,MS4A1,PPAPDC1B,CXCR5,ABCB4,CD200,FCRL1,FCRL2,CD79A,CD79B,ADAM28,CD19;KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY;0;0;75;6;[Chaussabel.v2]M4.10;0;0;32;9;;;;;;plasma membrane (17), protein binding (14), integral to membrane (13)
M70.0;TBA;TBA (M70.0);20;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M70.0.htm;CDKN2B,TCF15,PDLIM7,IL4I1 /// NUP62 /// SIGLEC11,ELAVL3,LTB4R2,SEC14L2,CFB,SAA1 /// SAA2,PSD,ADARB1,FUT7,ZNF205,CES4,SIX5,COL16A1,GP1BB,MSC,CLDN5,MAPRE3;;;;;;;;;;;NFKAPPAB65_01;0;0;190;5;protein binding (10), nucleus (7), cytoplasm (6)
M70.1;TBA;TBA (M70.1);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M70.1.htm;CDKN2B,PDLIM7,ELAVL3,SIX5,PIK3CD,SOX15,PSD,FUT7,BOK,FOXO4;;;;;;;;;;;;;;;;protein binding (8), cytoplasm (7), nucleus (5)
M71;enriched in antigen presentation (I);enriched in antigen presentation (I) (M71);18;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M71.htm;CD74,HLA-DPB1,HLA-DRA,CYP1B1,PLAUR,PTGS2,HMOX1,HLA-DRB1,ASPH,RTN1,HLA-DRB4,HLA-DQB1,FAR2,HLA-DPA1,ITPR3,HLA-DQA1,AGPAT9,SLC27A2;KEGG_ASTHMA;0;0;30;7;;;;;;;;;;;endoplasmic reticulum membrane (18), endoplasmic reticulum (17), membrane (16)
M72.0;TBA;TBA (M72.0);24;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M72.0.htm;MORC3,MUDENG,ADNP,DEK,ATP11B,FMR1,ARID4B,NEK7,PANK3,ORC4L,PLEKHF2,MST4,ITSN2,SACM1L,RNF138,RAP2C,PHTF2,ZBTB11,UBA3,EFHA1,PTPN11,ROCK1,RNF6,BZW1;;;;;;;;;;;;;;;;protein binding (14), cytoplasm (11), nucleus (10)
M72.1;TBA;TBA (M72.1);17;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M72.1.htm;NEK7,ITSN2,MUDENG,ERBB2IP,PLEKHF2,G3BP2,IMPA1,SP3,DEK,PPP1R12A,VPS4B,CCNC,FMR1,MBNL1,ARID4B,BZW1,SACM1L;;;;;;;;;;;;;;;;protein binding (14), cytoplasm (11), nucleus (8)
M72.2;TBA;TBA (M72.2);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M72.2.htm;ZDHHC17,LBR,ERBB2IP,PLEKHF2,STAG2,RNF111,SP3,PPP1R12A,G3BP2,FMR1,ARID4B,SACM1L;;;;;;[Chaussabel.v2]M4.9;0;0;94;3;TCCATTKW_UNKNOWN;0;0;185;4;protein binding (11), nucleus (7), cytoplasm (7)
M73;enriched in monocytes (III);enriched in monocytes (III) (M73);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M73.htm;CEBPB,DUSP6,MAML3,TFEC,FOS,IER3,CCR1,RIN2,GPR109B,BCL6,PLXDC2,TIMP2;;;;;;[Chaussabel.v2]M3.2;0;0;138;3;HMGIY_Q6;0;0;187;4;protein binding (8), regulation of transcription, DNA-dependent (5), nucleus (5)
M74;transcriptional targets of glucocorticoid receptor;transcriptional targets of glucocorticoid receptor (M74);12;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M74.htm;LOXL1,PPIL4 /// ZC3H12D,KCTD15,PSD3,SCD,CTGF,MEF2C,JUP,HLA-DOA,LOC100130458,CD3E,BTK;;;;;;;;;;;GRE_C;0;0;100;5;protein binding (9), plasma membrane (6), membrane (5)
M75;antiviral IFN signature;antiviral IFN signature (M75);22;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M75.htm;IFIH1,ELANE,SERPING1,IL1B,RSAD2,IFIT1,RARA,DDX58,FCER1A,DHX58,PTX3,CARD9,OAS1,OAS3,PML,ANXA3,HERC5,DDX60,CXCL10,IRF7,C1QB,BCL3;;;;;;[Chaussabel.v2]M1.2;0;0;27;7;;;;;;protein binding (15), cytoplasm (13), innate immune response (7)
M76;DNA repair;DNA repair (M76);22;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M76.htm;PCNA,RFC5,RFC4,RFC3,RFC2,FEN1,FANCD2,RPA1,MRE11A,FANCG,POLD1,POLD3,LIG1,FANCI,BRCA1,BRCA2,GTF2H1,H2AFX,RPA3,POLE2,RAD51,RAD50;KEGG_DNA_REPLICATION;0;0;36;12;;;;;;E2F4DP1_01;0;0;180;7;nucleoplasm (22), DNA repair (22), nucleus (21)
M77;collagen, TGFB family et al;collagen, TGFB family et al (M77);35;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M77.htm;PDGFRB,PDGFRA,PTK2,BCL11B,VDR,COL3A1,EDNRA,CD9,SEMA6A,CAMK1,JAM3,SULF1,JUP,NPY,THY1,TCF4,ENG,CD24,COL5A2,IGFBP3,COL4A2,COL4A1,TGFB1I1,SNAI2,ADM,SHANK3,GATA3,BMP2,FN1,POU4F1,MEF2C,FZD8,COL1A2,COL6A3,COL6A2;KEGG_FOCAL_ADHESION;0;0;201;11;;;;;;;;;;;protein binding (29), nucleus (13), plasma membrane (12)
M78;myeloid cell cytokines, metallopeptidases and laminins;myeloid cell cytokines, metallopeptidases and laminins (M78);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M78.htm;IL1RN,IL23A,IL10,MMP19,IL6,LAMC2,MMP9,EDN1,SFN,LAMB3,GSN;[PID]AP-1 transcription factor network;0;0;66;4;;;;;;AP1_Q4;0;0;214;11;extracellular region (11), protein binding (10), extracellular space (8)
M79;TBA;TBA (M79);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M79.htm;CXCL3,RNASE4,TFEC,DPYD,MGAM,FAM20C,SULF2,AQP9,ANPEP,TBXAS1;;;;;;;;;;;HNF1_Q6;0;0;200;10;plasma membrane (3), metal ion binding (3), integral to membrane (3)
M80;TBA;TBA (M80);20;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M80.htm;MEF2C,PTK2,FAM43A,ENG,RGL1,PLCB1,NDST3,GNG11,MGC5566,GAB1,LARGE,FAM69B,CTGF,TRAT1,MARCH3,GPR132,CCR9,CRIM1,HCP5,BLNK;;;;;;;;;;;E4BP4_01;0;0;164;5;protein binding (12), plasma membrane (8), integral to membrane (8)
M81;enriched in myeloid cells and monocytes;enriched in myeloid cells and monocytes (M81);35;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M81.htm;LIN7A,MYH10,PTGS1,EHD3,PCSK6,CCR2,CHI3L1,EGF,CLEC5A,FCER1G,NLRP3,ITGA2B,MMRN1,CSF1R,THBS1,SPARC,MARCKS,SLC8A1,PDGFA,ITGB3,HHEX,PROS1,TF,CLU,CXCL12,PRAM1,ACTN1,F5,CD14,FKBP1B,TLR7,TLR4,SNCA,BCL6,SELP;;;;;;;;;;;;;;;;protein binding (26), plasma membrane (18), blood coagulation (15)
M82;signal transduction, plasma membrane;signal transduction, plasma membrane (M82);13;signaling;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M82.htm;SFRP2,PDGFRB,PDGFRA,FN1,FAP,IGFBP5,DOCK4,NR2F2,COL1A2,COL1A1,SNAI2,LAMC1,DLC1;KEGG_FOCAL_ADHESION;0;0;201;6;;;;;;AAANWWTGC_UNKNOWN;0;0;163;4;protein binding (12), signal transduction (8), plasma membrane (6)
M83;enriched in naive and memory B cells;enriched in naive and memory B cells (M83);10;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M83.htm;NR3C2,PCDH9,NRXN3,PKIG,FCGR2B,CD37,MEF2C,BANK1,MS4A1,LY86;;;;;;;;;;;IRF1_Q6;0;0;201;10;protein binding (6), integral to membrane (5), plasma membrane (4)
M84;integrins and cell adhesion;integrins and cell adhesion (M84);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M84.htm;SELL,ITGB2,LILRB2,ITGB7,CD96,AMICA1,ITGA4,ICAM3,VCAM1,ITGAL;BIOCARTA_LYM_PATHWAY;0;0;11;5;;;;;;;;;;;regulation of immune response (10), protein binding (10), plasma membrane (10)
M85;platelet activation and degranulation;platelet activation and degranulation (M85);12;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M85.htm;SERPINA1,F3,TIMP1,FN1,THBS2,THBS1,SPARC,COL1A2,COL1A1,CLU,VWF,SERPINE1;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;6;;;;;;STAT6_01;0;0;199;3;protein binding (11), extracellular region (11), blood coagulation (11)
M86.0;chemokines and inflammatory molecules in myeloid cells;chemokines and inflammatory molecules in myeloid cells (M86.0);19;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M86.0.htm;CXCL1,TRAF1,ADORA2A /// CYTSA,CXCL2,NFKBIA,CCL4,BCL2A1,GCH1,G0S2,TNFAIP3,TNFAIP6,TNF,HS3ST3B1,NFKB1,SLAMF7,CCL20,IL1B,DUSP1,PDE4B;KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY;0;0;62;7;;;;;;;;;;;protein binding (11), signal transduction (9), inflammatory response (8)
M86.1;proinflammatory dendritic cell, myeloid cell response;proinflammatory dendritic cell, myeloid cell response (M86.1);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M86.1.htm;ADORA2A /// CYTSA,STAT4,CCL4,TNFAIP6,IFNG,CD80,GCH1,SERPINB9,TNF,HS3ST3B1,CCL20,IL1B,PDE4B;[PID]IL27-mediated signaling events;0;0;18;4;;;;;;;;;;;signal transduction (7), protein binding (7), immune response (6)
M87;transmembrane transport (I);transmembrane transport (I) (M87);24;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M87.htm;VDR,SLC7A7,CD36,SLC31A2,SLC4A1,TLR2,NLRP3,SLC11A1,ABCB6,CDH1,DAPK1,SLC14A1,AQP1,HK3,ATP1B2,AQP9,SLC25A21,SLC15A3,ABCG2,KCNH2,HMOX1,SLC22A4,RHAG,TLR4;;;;;;;;;;;;;;;;transmembrane transport (16), plasma membrane (16), membrane (14)
M88.0;leukocyte migration;leukocyte migration (M88.0);51;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M88.0.htm;C17orf73,HEPH,CDH17,POF1B,CDX1,CDX2,FAM3D,MYO1A,NOX1,PRSS3,C19orf21,FABP1,C2orf89,GPR35,BCL2L14,TMEM45B,MUC3B,PRR15L,TMPRSS2,CEACAM1,VIL1,GMDS,CEACAM5,CLDN3,CLDN4,KRT20,CLDN7,PLS1,XK,GUCY2C,GPX2,EPB41L4B,ATP10B,RNF43,ST14,EPCAM,TSPAN8,EPS8L3,MUC13,LGALS4,PIP5K1B,FA2H,ACSL5,MAPK13,NR1I2,FOXA3,FUT4,FUT3,MYO7B,GPA33,MEP1A;;;;;;;;;;;;;;;;protein binding (29), membrane (20), integral to membrane (20)
M88.1;enriched in hepatocyte nuclear factors (I);enriched in hepatocyte nuclear factors (I) (M88.1);13;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M88.1.htm;FOXA2,GMDS,MUC13,HNF4G,HNF4A,HNF1B,FOXA3,C19orf21,CEACAM5,PIP5K1B,EPS8L3,MNX1,LGALS4;KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG;0;0;25;6;;;;;;;;;;;protein binding (8), transcription, DNA-dependent (6), sequence-specific DNA binding transcription factor activity (6)
M88.2;enriched in hepatocyte nuclear factors (II);enriched in hepatocyte nuclear factors (II) (M88.2);12;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M88.2.htm;FOXA2,CDH17,GUCY2C,HNF4G,HNF4A,CALML4,HNF1B,FOXA3,C19orf21,CEACAM5,PIP5K1B,EPCAM;KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG;0;0;25;5;;;;;;HNF1_01;0;0;187;3;protein binding (8), transcription, DNA-dependent (5), transcription activator activity (5)
M89.0;putative targets of PAX3;putative targets of PAX3 (M89.0);16;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M89.0.htm;PLK2,G0S2,CXCL2,SIK1,EGR2,EGR3,CD83,EGR1,NR4A1,HBEGF,NR4A2,IL8,MAFF,CDKN1A,GEM,DUSP2;[PID]Calcineurin-regulated NFAT-dependent transcription in lymphocytes;0;0;42;4;;;;;;PAX3_B;0;0;102;8;protein binding (11), nucleus (9), signal transduction (7)
M89.1;putative targets of PAX3;putative targets of PAX3 (M89.1);10;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M89.1.htm;EGR2,EGR3,CD83,NR4A1,INHBA,NR4A2,RGS1,DUSP1,ATF3,DUSP2;;;;;;;;;;;HFH8_01;0;0;172;5;protein binding (7), nucleus (7), sequence-specific DNA binding transcription factor activity (5)
M90;TBA;TBA (M90);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M90.htm;HMGCS2,SLC3A1,CRABP2,CDX1,HNF4G,RNF186,MYO1A,SLC39A5,NR1I2,DDC,GIPC2,PPP1R14D;;;;;;;;;;;DR1_Q3;0;0;184;5;protein binding (6), cytoplasm (5), regulation of transcription, DNA-dependent (4)
M91;adhesion and migration, chemotaxis;adhesion and migration, chemotaxis (M91);13;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M91.htm;ANXA1,CX3CR1,CCL5,CCL19,PROK2,F2R,CXCR2,ADRB2,CCR5,CCR7,CCL21,CXCL13,PF4;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;9;;;;;;;;;;;inflammatory response (9), extracellular region (8), chemotaxis (8)
M92;lipid metabolism, endoplasmic reticulum;lipid metabolism, endoplasmic reticulum (M92);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M92.htm;PTGS2,CYP4F3,CYP1B1,TBXAS1,CYP4F12,MGST1,CYP3A7,CYP3A4,CYP3A5,CYP4F2;KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450;0;0;70;5;;;;;;;;;;;xenobiotic metabolic process (10), microsome (10), membrane (10)
M93;TBA;TBA (M93);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M93.htm;TGFBR3,LIF,IL23A,PRKCA,CRTAM,PLAU,CAMK4,TNF,OSM,PTCH1;;;;;;;;;;;NFKAPPAB_01;0;0;194;3;protein binding (8), plasma membrane (6), extracellular region (6)
M94;growth factor induced, enriched in nuclear receptor subfamily 4;growth factor induced, enriched in nuclear receptor subfamily 4 (M94);12;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M94.htm;PPP1R15A,PLK2,CYR61,NR4A2,EGR3,CDKN1A,NR4A1,EPHA2,ID1,IL6,NR4A3,DUSP1;[PID]AP-1 transcription factor network;0;0;66;3;;;;;;E4F1_Q6;0;0;209;8;protein binding (10), nucleus (7), sequence-specific DNA binding transcription factor activity (5)
M95.0;enriched in antigen presentation (II);enriched in antigen presentation (II) (M95.0);24;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M95.0.htm;CD53,IL10RA,ITGA4,FYB,HLA-DRA,HLA-DRB1 /// HLA-DRB4,HLA-DRB1 /// HLA-DRB4 /// HLA-DRB5,HLA-DRB1 /// HLA-DRB3 /// HLA-DRB4,HCLS1,PTPRC,HLA-DPB1,ITGB2,HLA-DRB1,GIMAP6,EVI2B,PLEK,SLA,SELL,IRF8,FGL2,ITGAL,ITGAM,AIF1,HLA-DMA;KEGG_CELL_ADHESION_MOLECULES_CAMS;0;0;134;10;;;;;;;;;;;protein binding (17), plasma membrane (14), integral to membrane (10)
M95.1;enriched in antigen presentation (III);enriched in antigen presentation (III) (M95.1);15;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M95.1.htm;FYB,CD53,HLA-DRA,ITGB2,ICAM1,PLEK,HLA-DRB1,LAPTM5,HLA-DRB1 /// HLA-DRB4 /// HLA-DRB5,PTPRC,HLA-DRB1 /// HLA-DRB3 /// HLA-DRB4,EVI2B,HLA-DMB,AIF1,HLA-DMA;BIOCARTA_BLYMPHOCYTE_PATHWAY;0;0;11;5;[Chaussabel.v2]M5.1;0;0;238;4;;;;;;protein binding (10), plasma membrane (9), integral to membrane (7)
M96;Hox cluster V;Hox cluster V (M96);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M96.htm;PRDM16,CPNE8,HOXB2,HOXB3,HOXB7,HOXA11,HOXA4,HOXA2,NKX2-3,HOXA9;;;;;;;;;;;HP1SITEFACTOR_Q6;0;0;178;5;protein binding (10), sequence-specific DNA binding (9), nucleus (9)
M97;enriched for SMAD2/3 signaling;enriched for SMAD2/3 signaling (M97);10;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M97.htm;P4HA2,TCL1A,RGL1,RUNX2,MEF2C,MME,BIVM,LAMC1,VPREB1,GATA3;[PID]Regulation of nuclear SMAD2/3 signaling;0;0;38;4;;;;;;;;;;;protein binding (7), nucleus (5), transcription, DNA-dependent (3)
M98.0;TBA;TBA (M98.0);18;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M98.0.htm;PLUNC,DMD,VSNL1,ERBB4,SPINLW1,OR10H3,TAS2R16,OPRM1,GRIN2B,HOXC10,DEFA5,HTR3B,GFRA3,C4orf31,ADH7,CYP11B1,NOS1AP,A2BP1;;;;;;;;;;;YY1_01;0;0;195;5;protein binding (9), receptor activity (7), plasma membrane (7)
M98.1;TBA;TBA (M98.1);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M98.1.htm;PLUNC,DMD,TUBB4,SLC7A11,DBC1,GRIN2B,DEFA5,CYP11B1,A2BP1,IFNA14;;;;;;;;;;;AP4_Q6_01;0;0;197;5;protein binding (5), plasma membrane (3), metal ion binding (3)
M99;TBA;TBA (M99);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M99.htm;PDGFRA,GREM1,CYR61,EPHA2,MRGPRF,FSTL1,INHBA,CTGF,DACT1,CAV1;;;;;;;;;;;NFKB_Q6;0;0;201;4;protein binding (8), plasma membrane (5), extracellular region (5)
M100;MAPK, RAS signaling;MAPK, RAS signaling (M100);10;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M100.htm;MAP4K1,RASGRP2,RAC2,RASGRP4,AKT1,TGFB1,MAP2K2,MAP3K11,ARRB2,FLNA;"[PID]TCR signaling in naïve CD4+ T cells";0;0;45;4;;;;;;MZF1_02;0;0;177;3;protein binding (8), cytoplasm (8), platelet activation (6)
M101;phosphatidylinositol signaling system;phosphatidylinositol signaling system (M101);14;signaling;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M101.htm;PHTF2,AGL,C6orf211,PIKFYVE,SP3,IMPA1,PIK3C2A,DEK,SYNJ1,PPP1R12A,CLK1,PIK3C3,EFHA1,SLC35A1;KEGG_INOSITOL_PHOSPHATE_METABOLISM;0;0;54;5;;;;;;;;;;;protein binding (8), nucleus (6), cytoplasm (6)
M102;TBA;TBA (M102);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M102.htm;AMOTL2,GHR,P2RX5,BTLA,CHRDL1,ELTD1,GNG12,SMAD1,STAP1,PNOC,CAV2,CD79A;;;;;;;;;;;;;;;;protein binding (9), plasma membrane (6), signal transduction (5)
M103;cell cycle (III);cell cycle (III) (M103);51;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M103.htm;SMC1A,HDAC2,BUB1B,PLK1,CDKN1B,CDKN1A,PKMYT1,MAD2L1,ATR,CDC6,CDC7,CCNA2,CCNE2,SMC3,CCNE1,ANAPC10,TTK,ESPL1,DBF4,WEE1,CHEK2,CHEK1,PCNA,CDKN2C,CDKN2A,BUB1,RBL1,RBL2,RAD21,CDC25C,CDC25A,E2F5,MCM7,MCM6,MCM5,MCM4,MCM3,MCM2,PTTG1,SKP2,CCNB2,CCNB1,E2F2,E2F1,CDC23,CDC20,CDK1,CDK2,CDK4,CDC45,TFDP1;KEGG_CELL_CYCLE;0;0;128;51;;;;;;E2F_Q6_01;0;0;170;13;protein binding (49), nucleus (45), mitotic cell cycle (43)
M104;TBA;TBA (M104);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M104.htm;PDGFRA,ZNF423,MGLL,GNAZ,FSTL1,MEF2C,JUP,MLLT3,CRIM1,PF4;;;;;;[Chaussabel.v2]M1.1;0;0;86;3;HFH4_01;0;0;167;10;protein binding (7), plasma membrane (5), nucleus (5)
M105;TBA;TBA (M105);18;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M105.htm;CDKN2C,H1F0,BEX1,PROK2,BPI,CA2,PTX3,RETN,CLEC11A,SLC22A4,MGST1,LPCAT2,IGFBP7,CPNE2,IRAK3,JAG1,VSTM1,BTBD3;;;;;;;;;;;;;;;;protein binding (10), extracellular region (7), nucleus (6)
M106.0;nuclear pore complex;nuclear pore complex (M106.0);17;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M106.0.htm;NUP88,XPO1,NUP62,NUPL2,NUP133,NUP107,RAN,NUP160,NUP54,NUP35,NUP85,NUP37,NUP43,NUP155,SEH1L,RANBP1,NUP205;;;;;;;;;;;;;;;;viral reproduction (17), nucleus (17), protein transport (15)
M106.1;nuclear pore complex (mitosis);nuclear pore complex (mitosis) (M106.1);11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M106.1.htm;SMC1A,SLBP,SEH1L,NUP133,NUP107,GTF2H1,NUP85,NUP37,NUP43,CCNH,NUP160;;;;;;;;;;;;;;;;protein binding (11), nucleus (11), viral reproduction (9)
M107;Hox cluster VI;Hox cluster VI (M107);11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M107.htm;HOXB9,HOXB2,HOXB3,HOXB6,HOXA10,HOXA6,HOXA4,HOXA3,HOXA2,C10orf140,HOXA9;;;;;;;;;;;PIT1_Q6;0;0;185;7;nucleus (11), sequence-specific DNA binding transcription factor activity (10), sequence-specific DNA binding (10)
M108;TBA;TBA (M108);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M108.htm;EPHB2,MUC3B,AXIN2,GPX2,ASCL2,RNF43,EHF,C19orf21,CEACAM5,CDCA7,TSPAN8;;;;;;;;;;;IK2_01;0;0;211;4;protein binding (5), nucleus (5), regulation of transcription, DNA-dependent (3)
M109;receptors, cell migration;receptors, cell migration (M109);15;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M109.htm;TGFBR3,NCKAP1L,LRRK2,C3AR1,S1PR1,SYNE2,IL6R,CCR1,CCR2,CORO1A,TRIB1,CCR7,LEF1,GATA3,BCL2;;;;;;;;;;;;;;;;plasma membrane (11), protein binding (10), integral to membrane (8)
M110;axon guidance;axon guidance (M110);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M110.htm;MYH10,PTK2,DPYSL3,RRAS,COL5A1,COL1A2,COL1A1,RHOC,NRP1,SEMA6A;KEGG_FOCAL_ADHESION;0;0;201;4;;;;;;;;;;;axon guidance (10), protein binding (9), signal transduction (8)
M111.0;"viral sensing & immunity; IRF2 targets network (I)";"viral sensing & immunity; IRF2 targets network (I) (M111.0)";17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M111.0.htm;TAP1,KYNU,TLR7,ZBP1,IFI35,LY86,THBS1,TNFSF13B,PSMB8,EREG,FES,BST2,USP18,CTSS,RIPK2,AIF1,CXCL16;;;;;;;;;;;ICSBP_Q6;0;0;190;17;protein binding (11), plasma membrane (7), extracellular region (6)
M111.1;"viral sensing & immunity; IRF2 targets network (II)";"viral sensing & immunity; IRF2 targets network (II) (M111.1)";11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M111.1.htm;TAP1,DDX58,PSMB10,ZBP1,CASP1,PSMB8,BST2,CXCL10,USP18,IFIT2,TNFSF13B;KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY;0;0;56;4;[Chaussabel.v2]M3.4;0;0;53;3;IRF_Q6;0;0;151;11;protein binding (6), nucleus (5), cytoplasm (5)
M112.0;complement activation (I);complement activation (I) (M112.0);17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M112.0.htm;CR1,CFH,CFI,SERPING1,C3AR1,CFD,C1QC,C1QB,C1QA,C3,CFB,C5AR1,C2,C1S,C1R,C7,A2M;KEGG_COMPLEMENT_AND_COAGULATION_CASCADES;0;0;69;17;;;;;;;;;;;extracellular region (14), innate immune response (13), protein binding (12)
M112.1;complement activation (II);complement activation (II) (M112.1);10;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M112.1.htm;CFH,CFI,PROS1,CFB,C3,IL33,CLU,C1S,C1R,C7;KEGG_COMPLEMENT_AND_COAGULATION_CASCADES;0;0;69;8;;;;;;STAT5B_01;0;0;192;3;extracellular region (10), protein binding (9), innate immune response (7)
M113;golgi membrane (I);golgi membrane (I) (M113);10;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M113.htm;B3GNT5,FAM198B,WLS,PDGFC,LPCAT2,SGMS2,SORT1,TLR8,STEAP4,CSGALNACT1;;;;;;[Chaussabel.v2]M7.10;0;0;106;3;;;;;;membrane (8), integral to membrane (8), Golgi apparatus (8)
M114.0;TBA;TBA (M114.0);39;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M114.0.htm;ELANE,SVIL,DOCK5,PKP4,OSBPL1A,CLGN,MGST1,VSTM1,MS4A3,AKR1C3,LGALS12,KCNK5,RGL4,FAH,NFE2,ST3GAL6,JAG1,GGH,PDGFC,TAL1,CDK6,ATP8B4,ACTN1,CLEC11A,TSPAN2,CPNE2,IGFBP7,C5orf13,ACCN2,ZNRF1,SLC40A1,SYNGR1,MPO,RUNX2,MLC1,BST1,FAM105A,CPA3,BTBD3;;;;;;;;;;;;;;;;protein binding (19), membrane (14), cytoplasm (13)
M114.1;glycerophospholipid metabolism;glycerophospholipid metabolism (M114.1);11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M114.1.htm;SVIL,SLC40A1,OSBPL1A,MBOAT2,FAH,ST3GAL6,LPCAT2,IGFBP7,PLA2G4A,AGPAT9,AKR1C3;KEGG_GLYCEROPHOSPHOLIPID_METABOLISM;0;0;77;4;;;;;;;;;;;integral to membrane (5), protein binding (4), metabolic process (4)
M115;cytokines - recepters cluster;cytokines - recepters cluster (M115);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M115.htm;IL7R,IL2RA,LIF,IL23A,IFNG,IL15,CSF2,CSF3,IL6,IL10,IL15RA;KEGG_JAK_STAT_SIGNALING_PATHWAY;0;0;155;11;;;;;;AML_Q6;0;0;198;4;immune response (10), extracellular region (10), extracellular space (8)
M116;TBA;TBA (M116);13;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M116.htm;ERRFI1,PDGFRA,CYR61,WWTR1,FSTL1,YAP1,OSMR,VCAM1,EPS8,GPR116,COL3A1,CXCL12,CAV1;;;;;;;;;;;;;;;;protein binding (12), plasma membrane (6), positive regulation of cell proliferation (5)
M117;cell adhesion (GO);cell adhesion (GO) (M117);21;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M117.htm;PPP2R1A,CD40LG,NELL2,CD96,NINJ1,PSTPIP1,LY9,ADAM9,CXCR3,CD6,CORO1A,PTPRC,ZAP70,SPOCK2,PRKCQ,SELPLG,CYTIP,CD300A,PLEK,LEF1,BCL2;;;;;;;;;;;;;;;;protein binding (19), cytoplasm (11), cell adhesion (11)
M118.0;enriched in monocytes (IV);enriched in monocytes (IV) (M118.0);57;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M118.0.htm;PTGS2,EMR1,AMICA1,DOCK5,CD4,LY96,ARHGEF10L,TNFSF13B,LTBR,PGD,TNFRSF1B,LRRK2,DPYD,MGAM,PTX3,LYZ,IL1R2,DOK3,CARD9,EVI5,GPR109B,DUSP6,MYO1F,FGD4,HHEX,HAL,ST3GAL6,DYSF,RNASE6,SLC24A4,VNN1,NAIP,RHOU,CD68,CXCR2,NACC2,SMARCD3,PADI4,TMEM176B,LGALS3,SAMHD1,CTSS,EMILIN2,ACPP,F5,STEAP4,C19orf59,ACSL1,PAK1,C1orf162,MOSC1,TLR1,PID1,BCL6,HLA-DMB,MPP1,AGPAT9;;;;;;;;;;;;;;;;protein binding (35), plasma membrane (23), integral to membrane (23)
M118.1;enriched in monocytes (surface);enriched in monocytes (surface) (M118.1);17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M118.1.htm;LTBR,CD4,TNFRSF1B,MCTP1,S1PR3,EMR1,C19orf59,SLC24A4,STEAP4,C1orf162,SLC16A3,NFAM1,TMEM176B,HLA-DMB,IL1R2,AGPAT9,TNFSF13B;;;;;;;;;;;;;;;;integral to membrane (17), plasma membrane (11), membrane (10)
M119;enriched in activated dendritic cells (I);enriched in activated dendritic cells (I) (M119);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M119.htm;IL1RN,CXCL2,RGL1,CD83,PRKCD,CD86,RIN2,SLAMF8,IL4I1,ATP1B1,PLXDC2;;;;;;;;;;;NFKB_Q6;0;0;201;11;protein binding (8), plasma membrane (5), signal transduction (4)
M120;TBA;TBA (M120);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M120.htm;DGKZ,MAP4K1,LPXN,VAV1,HCLS1,ARHGAP15,ARRB2,SIGIRR,ARHGAP4,LYN,GATA3;[PID]Signaling events mediated by Stem cell factor receptor (c-Kit);0;0;46;3;;;;;;ETS_Q4;0;0;180;11;protein binding (9), cytoplasm (7), signal transduction (6)
M121;TBA;TBA (M121);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M121.htm;IGKV4-1,TAP1,IRF4,CCL19,GPR183,CD27,IL15,BIRC3,LY9,PLSCR1,SLAMF7,IGKC;;;;;;;;;;;;;;;;protein binding (10), integral to membrane (5), immune response (5)
M122;enriched for cell migration;enriched for cell migration (M122);11;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M122.htm;CCL2,PODN,TGFB2,IGF1,LAMA4,NBL1,MYLK,NR2F2,IGFBP5,CXCL12,NRP1;;;;;;;;;;;SRF_Q6;0;0;211;4;protein binding (9), extracellular region (9), signal transduction (6)
M123;enriched in B cell differentiation;enriched in B cell differentiation (M123);13;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M123.htm;ICOSLG,HBEGF,LOC144481,NR4A1,GAB1,DLL1,LOC100288911,NR4A3,EBF1,FAM150B,BCL11B,VPREB1,VPREB3;;;;;;;;;;;PAX3_B;0;0;65;4;protein binding (9), signal transduction (4), regulation of transcription, DNA-dependent (4)
M124;enriched in membrane proteins;enriched in membrane proteins (M124);19;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M124.htm;ABCG2,RHAG,LTF,AQP1,C3AR1,HP,HLA-DRB1,ELANE,CD24,NEDD4L,ALAS2,C5AR1,SLC4A1,ABCB6,SNCA,PROK2,TGM2,SLC40A1,KCNH2;;;;;;[Chaussabel.v2]M2.3;0;0;71;5;;;;;;plasma membrane (12), protein binding (11), integral to plasma membrane (8)
M125;TBA;TBA (M125);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M125.htm;CDKN2B,GPR144,ZNF205,ELAVL3,TCF15,SOX15,PRKCG,GP1BB,FUT7,PSD,MAPRE3;;;;;;;;;;;RFX1_02;0;0;195;4;protein binding (7), nucleus (5), cytoplasm (5)
M126;double positive thymocytes;double positive thymocytes (M126);13;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M126.htm;MGC16121,TCF4,UBASH3A,SLC40A1,SH2D1A,APBB1,BCL11B,CD4,CHI3L2,ASRGL1,PCSK5,LAT /// SPNS1,CD3E;;;;;;;;;;;NFMUE1_Q6;0;0;181;6;protein binding (9), nucleus (5), cytoplasm (5)
M127;type I interferon response;type I interferon response (M127);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M127.htm;TAP1,IFIH1,IRF7,PARP9,STAT1,PLSCR1,IFITM1,HERC5,DDX60,USP18,RSAD2,IFIT1;;;;;;[Chaussabel.v2]M3.4;0;0;53;6;;;;;;protein binding (9), cytosol (7), response to virus (6)
M128;TBA;TBA (M128);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M128.htm;SP3,NDUFA5,USP1,CCNC,PIK3C2A,SFRS12,CLK1,RNF6,ARID4A,CCNT2,PSMC6,RNF139;;;;;;[Chaussabel.v2]M6.3;0;0;94;3;E2F1_Q4_01;0;0;169;4;nucleus (9), protein binding (7), cytoplasm (4)
M129;inositol phosphate metabolism;inositol phosphate metabolism (M129);13;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M129.htm;PANK3,AVL9,PIKFYVE,MED23,PLEKHF2,SRP9,IMPA1,PIK3C2A,SYNJ1,CASC4,FNDC3A,PIK3C3,KIAA1109;KEGG_INOSITOL_PHOSPHATE_METABOLISM;0;0;54;5;;;;;;;;;;;protein binding (7), nucleotide binding (5), membrane (5)
M130;enriched in G-protein coupled receptors;enriched in G-protein coupled receptors (M130);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M130.htm;CCL5,XCL1,PTGER2,GPR18,F2R,ADRB2,S1PR5,PTGDR,ITPR3,PDE4D;KEGG_CALCIUM_SIGNALING_PATHWAY;0;0;178;3;;;;;;CEBPB_02;0;0;208;3;G-protein coupled receptor protein signaling pathway (7), receptor activity (6), plasma membrane (6)
M131;TBA;TBA (M131);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M131.htm;HEMGN,ACTN1,GFI1B,XK,CMPK2,RGL4,S100P,FHL2,INHBA,PRKAR2B,TAL1,TNS1,MS4A3,GMPR;;;;;;;;;;;CCCNNNNNNAAGWT_UNKNOWN;0;0;76;4;protein binding (9), nucleus (6), cytoplasm (6)
M132;recruitment of neutrophils;recruitment of neutrophils (M132);11;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M132.htm;PROK2,FPR1,FPR2,GNG10,C5AR1,GPR109B,CXCR1,CCR3,PTAFR,FFAR2,F2RL1;KEGG_CHEMOKINE_SIGNALING_PATHWAY;0;0;190;3;;;;;;;;;;;G-protein coupled receptor protein signaling pathway (11), plasma membrane (9), integral to membrane (9)
M133.0;cell adhesion, membrane;cell adhesion, membrane (M133.0);14;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M133.0.htm;SFN,SPINT1,BIK,EHF,JUP,LSR,EPS8L1,CDH1,EPCAM,CDH3,CLDN3,CLDN4,KRT19,CLDN7;KEGG_CELL_ADHESION_MOLECULES_CAMS;0;0;134;5;;;;;;AREB6_01;0;0;202;4;protein binding (13), plasma membrane (8), membrane (7)
M133.1;cell cell adhesion;cell cell adhesion (M133.1);11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M133.1.htm;LAMA3,ITGB4,ITGB6,LAMC2,JUP,CDH1,CDH3,CLDN3,CLDN4,LAMB3,CLDN7;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;5;;;;;;AREB6_01;0;0;202;4;protein binding (10), membrane (9), plasma membrane (8)
M134;Membrane, ER proteins;Membrane, ER proteins (M134);17;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M134.htm;C10orf10,NAV1,MRVI1,PTK2,CD72,ENG,RGL1,CIITA,SH2D4B,RASAL2,LARGE,STK32B,EMP2,CORO2B,CSRP2,TMED6,DHCR24;;;;;;;;;;;LEF1_Q2;0;0;175;6;protein binding (9), membrane (7), integral to membrane (6)
M135.0;enriched in plasma membrane proteins (I);enriched in plasma membrane proteins (I) (M135.0);16;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M135.0.htm;LRP2,ENPEP,GALNT14,ALPK2,SEMA5B,BBOX1,CUBN,PAX2,DGCR5,AGXT2,SLC6A13,LOC100130232,NHLH2,NAT8 /// NAT8B,GAL3ST1,SLC17A3;;;;;;;;;;;NKX25_02;0;0;203;5;integral to membrane (6), protein binding (5), membrane (5)
M135.1;enriched in plasma membrane proteins (II);enriched in plasma membrane proteins (II) (M135.1);15;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M135.1.htm;ENPEP,GALNT14,ALPK2,KCNJ16,CUBN,SLC3A1,DGCR5,SLC17A3,SLC6A13,ESM1,COL23A1,NAT8 /// NAT8B,GAL3ST1,ACMSD,DSCAML1;;;;;;;;;;;TEF_Q6;0;0;197;4;plasma membrane (7), integral to membrane (7), protein binding (5)
M136;TBA;TBA (M136);17;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M136.htm;NUCB1,GPS1,ASNA1,COPE,PKN1,GNAI2,CTSD,GNB2,PPP2R1A,MAP2K2,NAPA,CAPN1,DNM2,FAM108A1,GBF1,NR1H2,PNPLA6;;;;;;;;;;;;;;;;protein binding (12), cytoplasm (11), nucleus (7)
M137;TBA;TBA (M137);16;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M137.htm;ZMYM2,PHTF2,PANK3,AGL,TLK1,TSNAX,PIKFYVE,USP1,PLEKHF2,TCERG1,ROCK1,ACBD3,SFRS12,RNF6,SMARCA5,ATF2;;;;;;;;;;;STAT_Q6;0;0;192;6;protein binding (11), nucleus (11), metal ion binding (6)
M138;enriched for ubiquitination;enriched for ubiquitination (M138);11;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M138.htm;PHTF2,UBE2Q2,RPS6KB1,NRAS,SRP9,ZBTB41,PIK3C2A,USP1,RNF6,MBNL2,UBR1;;;;;;;;;;;HFH4_01;0;0;167;5;protein binding (8), nucleus (7), cytoplasm (7)
M139;lysosomal/endosomal proteins;lysosomal/endosomal proteins (M139);11;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M139.htm;CTSH,SLC11A1,PSAP,CTSB,CTSD,CD68,NPC2,AP1S2,SORT1,CTSS,GAA;KEGG_LYSOSOME;0;0;121;11;;;;;;;;;;;lysosome (8), membrane (5), extracellular region (5)
M140;extracellular matrix, complement;extracellular matrix, complement (M140);14;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M140.htm;SLPI,CRISPLD2,FCN1,LTBP2,PRTN3,LAMA2,TFF3,FLRT2,IGFBP7,CRISP3,MMP9,MMP8,CFP,TIMP2;;;;;;;;;;;;;;;;extracellular region (12), extracellular matrix (9), protein binding (7)
M141;TBA;TBA (M141);27;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M141.htm;TRIM31,FABP1,FUT4,NOX1,C19orf21,EPCAM,PRR15L,B3GNT5,B3GNT3,CEACAM1,KLF5,GMDS,CEACAM6,TMEM45B,ST3GAL6,TMPRSS2,CKMT1A /// CKMT1B,FERMT1,HEPH,LGALS4,PIP5K1B,FA2H,NR1I2,FOXA3,GPX2,FUT3,MEP1A;;;;;;;;;;;;;;;;protein binding (11), membrane (10), integral to membrane (10)
M142;transmembrane and ion transporters (I);transmembrane and ion transporters (I) (M142);13;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M142.htm;ASPA,NLGN1,CUBN,SLC13A1,SLC28A1,SLC17A1,LOC100422737,SLC17A3,LOC100130232,PAX2,SLC6A13,KCNIP4,SEMA5B;;;;;;;;;;;PITX2_Q2;0;0;210;4;plasma membrane (7), transmembrane transport (5), membrane (5)
M143;"nuclear pore, transport; mRNA splicing, processing";"nuclear pore, transport; mRNA splicing, processing (M143)";11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M143.htm;SLBP,NCBP2,NUP133,NUP107,NUP160,NUP54,UPF3B,NUP155,SEH1L,NUPL2,NUP205;;;;;;;;;;;GKCGCNNNNNNNTGAYG_UNKNOWN;0;0;45;3;nucleus (11), protein binding (10), viral reproduction (9)
M144;cell cycle, ATP binding;cell cycle, ATP binding (M144);16;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M144.htm;RBM7,NEK7,UBA3,HDAC2,TLK1,MCTS1,RAD21,COPS5,PCNP,PSMA6,PPP1R12A,VPS4B,CCNC,CUL5,PSMC6,ERBB2IP;;;;;;;;;;;;;;;;protein binding (15), nucleus (12), cytoplasm (10)
M145.0;cytoskeleton/actin (SRF transcription targets);cytoskeleton/actin (SRF transcription targets) (M145.0);16;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M145.0.htm;ACTA2,MYH11,MRVI1,SDPR,SVIL,ACTG2,CALD1,MYLK,MRGPRF,TPM2,PALLD,TPM1,EPS8,PLN,CAV2,TAGLN;KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION;0;0;115;6;;;;;;SRF_Q4;0;0;74;11;cytoplasm (11), protein binding (9), cytosol (9)
M145.1;cytoskeleton/actin (SRF transcription targets);cytoskeleton/actin (SRF transcription targets) (M145.1);14;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M145.1.htm;ACTA2,MYH11,ACTG2,LMOD1,CALD1,MYLK,TPM1,TPM2,SYNPO2,SORBS1,TNS1,CAV2,VCL,MYL9;KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION;0;0;115;6;;;;;;SRF_Q4;0;0;191;8;cytosol (12), muscle contraction (11), cytoplasm (11)
M146;MHC-TLR7-TLR8 cluster;MHC-TLR7-TLR8 cluster (M146);17;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M146.htm;CD74,HLA-DPB1,HLA-DRA,HLA-C,HLA-B,HLA-A,HLA-DRB1,HLA-G,HLA-F,HLA-DRB4,CD4,HLA-DQB1,HLA-E,HLA-DPA1,TLR8,HLA-DQA1,TLR7;KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION;0;0;89;15;;;;;;;;;;;protein binding (17), plasma membrane (16), membrane (15)
M147;intracellular transport;intracellular transport (M147);17;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M147.htm;SIRT1,EXOC1,VPS4B,NUP133,NUP107,CEP120,CLINT1,ZFYVE16,PIKFYVE,SEC63,ZFAND6,PIK3C2A,TMX1,PPP1R12A,RAD21,G3BP2,SRP9;;;;;;;;;;;;;;;;protein binding (15), cytoplasm (9), cytosol (7)
M148;TBA;TBA (M148);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M148.htm;MORC3,SEC23A,SPAST,EEA1,NUP160,RB1,ADAM9,STXBP3,SYNJ1,SEC24B,TMEM30A;;;;;;;;;;;;;;;;protein binding (9), cytoplasm (6), zinc ion binding (5)
M149;TBA;TBA (M149);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M149.htm;GREB1,SLC3A1,SIX4,HNF4G,RNF186,CLRN3,USH1C,CLDN2,GIPC2,TFAP2C;;;;;;;;;;;HSF2_01;0;0;187;4;protein binding (5), membrane (4), integral to membrane (4)
M150;innate antiviral response;innate antiviral response (M150);12;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M150.htm;TAP1,IRF7,PLSCR1,EIF2AK2,APOBEC3A,OASL,RXRA,OAS1,OAS3,RSAD2,IFIT1,SP100;;;;;;[Chaussabel.v2]M1.2;0;0;27;5;;;;;;protein binding (8), type I interferon-mediated signaling pathway (6), cytokine-mediated signaling pathway (6)
M151;TBA;TBA (M151);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M151.htm;PRKCH,ZNF521,GREM1,TIAM1,SMAD1,RORA,BCL11B,INHBA,ADAM12,HHIP;;;;;;;;;;;FREAC2_01;0;0;198;10;protein binding (9), metal ion binding (6), zinc ion binding (5)
M152.0;TBA (source: B cells);TBA (source: B cells) (M152.0);25;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M152.0.htm;HTN1,CCR9,ST18,TAT,GAGE1,LOC100287445,IFNA10,IFNA16,TRDN,FAM123A,HERC2P7,PPEF2,POU4F2,TRIM49,GABRB1,ZPBP,LOC100271840,SYCP1,IMPG2,KCTD16,TMEFF2,LOC51152,MEFV,BAGE,LOC100131298;;;;;;;;;;;;;;;;protein binding (12), integral to membrane (5), extracellular region (5)
M152.1;TBA (source: naive B cells);TBA (source: naive B cells) (M152.1);21;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M152.1.htm;POU4F2,TAT,FAM123A,OR7E24,IMPG2,KCTD16,HERC2P7,LRRC37B2,TMEFF2,ANKRD20A1,LOC100286993,LOC100271840,LOC100132247,GTF2A1L,MEFV,TRIM49,ADAMTS20,LOC100286895,TPTE,IFNA10,LOC100131298;;;;;;;;;;;;;;;;protein binding (9), membrane (4), integral to membrane (4)
M152.2;TBA (source: memory B cells);TBA (source: memory B cells) (M152.2);18;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M152.2.htm;TAT,FAM123A,C14orf91,HERC2P7,TMEFF2,HTN1,PPEF2,MEFV,LOC51152,LOC100286993,GYPA,BAGE,ADAMTS20,GABRB1,CYP4A22,IFNA10,ZPBP,LOC100271840;;;;;;;;;;;;;;;;protein binding (6), extracellular region (5), metal ion binding (4)
M153;TBA;TBA (M153);16;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M153.htm;PHTF2,SP3,SEC23A,RAP2C,SGTB,AEBP2,NRAS,SRP9,C1D,PIK3C2A,CCNC,RNF6,FAM18B,C2orf69,RANBP6,TCF12;;;;;;;;;;;PAX4_04;0;0;164;5;protein binding (10), nucleus (9), regulation of transcription, DNA-dependent (6)
M154.0;amino acid metabolism and transport;amino acid metabolishm and transport (M154.0);33;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M154.0.htm;FXYD2,BBOX1,NAT8 /// NAT8B,AGXT2,BHMT2,DMGDH,GAL3ST1,BHMT,SLC7A9,ACSM5,ACSM2A /// ACSM2B /// LOC100291873,DPYS,LOC100130232,NR1H4,SLC6A12,GBA3,PDZK1,NAT8,SLCO4C1,ACSM2A,SLC6A13,RBP5,AGMAT,ACMSD,ACSM2A /// ACSM2B,SLC3A1,TMEM27,SLC17A1,LOC100422737,SLC17A3,C14orf105,GLYAT,SLC22A2;;;;;;;;;;;;;;;;integral to membrane (10), transmembrane transport (9), metal ion binding (9)
M154.1;transmembrane transport (SLC cluster);transmembrane transport (SLC cluster) (M154.1);17;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M154.1.htm;SLC22A11,FXYD2,NLGN1,SLC13A1,SLC2A2,SLC28A1,SLC7A9,SLC16A4,SLC17A1,SLC5A10,SLC22A2,SLC3A1,SLC6A13,SLC6A12,SLC17A3,SLCO4C1,PDZK1;;;;;;;;;;;;;;;;transmembrane transport (15), plasma membrane (14), integral to plasma membrane (12)
M155;G protein coupled receptors cluster;G protein coupled receptors cluster (M155);10;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M155.htm;S1PR3,C3AR1,FPR2,PTH2R,PTGER2,LTB4R,PTAFR,FPR1,P2RY2,PTGDR;;;;;;;;;;;;;;;;plasma membrane (10), integral to membrane (10), G-protein coupled receptor protein signaling pathway (10)
M156.0;plasma cells & B cells, immunoglobulins;plasma cells & B cells, immunoglobulins (M156.0);43;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M156.0.htm;CD52,IGKV4-1,LOC652493,IGHG1,C13orf18,LOC100287723,LOC100289053,IGKC,IGKV1D-13,VPREB3,ITM2C,LOC96610,IGLV4-60,IGLV3-19,P2RX5,CPNE5,ADAM28,STAP1,ABCB4,FCRL1,FCRL2,PCDH9,CD22,IGL@,LOC91316,SPIB,IGKV3-20,IGHD,BLK,LOC100290557,IGLV2-23,IGJ,OSBPL10,CYAT1,E2F5,LOC100293440,TNFRSF17,IGLV1-44,IGLJ3,GNG7,IGLL3,MGC29506,IGLL5;;;;;;;;;;;;;;;;protein binding (24), plasma membrane (9), integral to membrane (7)
M156.1;plasma cells, immunoglobulins;plasma cells, immunoglobulins (M156.1);36;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M156.1.htm;IGKV4-1,LOC652493,IGHA1,IGHG1,TNFRSF17,LOC100287723,LOC100289053,IGK@,IGKC,IGKV1D-13,LOC96610,IGLV3-19,TXNDC5,DERL3,LOC100290557,MUTED,CD27,IGL@,LOC91316,IGH@,IGKV3-20,IGHD,IGHV3-48,PNOC,IGLV2-23,IGHM,CYAT1,LOC100130100,IGKV1-5,LOC100293440,POU2AF1,IGLV1-44,IGLJ3,IGLV4-60,MGC29506,IGLL5;;;;;;;;;;;;;;;;protein binding (20), extracellular region (9), immune response (8)
M157;enriched in NK cells (III);enriched in NK cells (III) (M157);14;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M157.htm;KLRC3,PPP1R16B,RASGRP1,CCL4,CX3CR1,GPR18,TIGIT,CD7,C1orf21,PVRIG,GIMAP6,TRGC2,MATK,PTPN4;;;;;;;;;;;;;;;;protein binding (8), plasma membrane (7), integral to membrane (6)
M158.0;interferon alpha response (I);interferon alpha response (I) (M158.0);16;immune;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M158.0.htm;LHCGR,COL8A1,IMPG2,ITGB4,MMP12,TNR,IFNA7,IFNA4,SFN,LAMC2,ST14,ADAMTS20,FGF5,IFNA10,IFNA16,IFNA14;KEGG_REGULATION_OF_AUTOPHAGY;0;0;35;5;;;;;;;;;;;extracellular region (12), extracellular space (11), protein binding (7)
M158.1;interferon alpha response (II);interferon alpha response (II) (M158.1);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M158.1.htm;LHCGR,FAM123A,IFNA8,IFNA2,IFNA7,IFNA5,IFNA4,IFNA21,PRL,ADAMTS20,IFNA10,IFNA16,IFNA14;KEGG_REGULATION_OF_AUTOPHAGY;0;0;35;9;;;;;;;;;;;extracellular space (11), extracellular region (11), type I interferon-mediated signaling pathway (9)
M159;G protein mediated calcium signaling;G protein mediated calcium signaling (M159);10;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M159.htm;PLCB1,GNAQ,CAMK4,GNAZ,ADCY9,GNA15,GNG11,PRKAR2B,CALM3,GNAI1;KEGG_CALCIUM_SIGNALING_PATHWAY;0;0;178;6;;;;;;RREB1_01;0;0;163;3;signal transduction (8), plasma membrane (7), nucleotide binding (7)
M160;leukocyte differentiation;leukocyte differentiation (M160);16;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M160.htm;KLF13,RARA,LIF,NAA15,BTG2,EGR2,CD83,JUNB,ADAM8,ID1,KLF6,MED1,NR4A2,IL1A,NFKB2,BCL3;;;;;;;;;;;AP2ALPHA_01;0;0;177;4;protein binding (13), nucleus (11), regulation of transcription, DNA-dependent (10)
M161;TBA;TBA (M161);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M161.htm;BCL2L1,SP3,TSNAX,SPAST,SLC7A5,RB1,RBM38,HERC4,RNF6,FNDC3A,MBNL3,ATF1,KIAA1109,BNIP2;;;;;;;;;;;;;;;;nucleus (10), cytoplasm (9), protein binding (8)
M162.0;plasma membrane, cell junction;plasma membrane, cell junction (M162.0);18;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M162.0.htm;TMC4,TJP3,SPINT1,LLGL2,GRHL2,PRR15L,MYH14,MAL2,ST14,EHF,ESRP1,PKP3,CDH1,EPCAM,ELF3,CLDN3,CLDN4,CLDN7;KEGG_TIGHT_JUNCTION;0;0;134;6;;;;;;;;;;;protein binding (13), plasma membrane (8), membrane (6)
M162.1;cell junction;cell junction (M162.1);11;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M162.1.htm;BSPRY,EPB41L5,TJP3,DSP,PKP3,CDH1,EPCAM,CLDN3,CLDN4,S100A14,CLDN7;KEGG_CELL_ADHESION_MOLECULES_CAMS;0;0;134;4;;;;;;;;;;;protein binding (10), plasma membrane (9), cell junction (9)
M163;enriched in neutrophils (II);enriched in neutrophils (II) (M163);14;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M163.htm;NPL,ARAP3,HSPA6,TYROBP,CFD,IMPA2,DENND3,BTNL8,FRAT2,MBOAT7,TSPAN2,BEST1,FLJ10357,SLC40A1;;;;;;;;;;;;;;;;protein binding (5), integral to membrane (5), plasma membrane (4)
M164;xenobiotic metabolism;xenobiotic metabolism (M164);10;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M164.htm;LRRC19,HHLA2,SLC3A1,UGT2A3,DPYS,UPB1,CYP3A7,GIPC2,CYP3A5,C19orf77;KEGG_DRUG_METABOLISM_OTHER_ENZYMES;0;0;51;5;;;;;;;;;;;membrane (6), metal ion binding (4), integral to membrane (4)
M165;enriched in activated dendritic cells (II);enriched in activated dendritic cells (II) (M165);35;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M165.htm;CSF2RB,IFIH1,CSF2RA,TNFAIP6,HESX1,CCL8,MX2,DOCK4,PDGFRL,MGST1,IFNGR2,IFIT3,IFIT2,IFIT1,HLX,SERPING1,RSAD2,CCL20,ST3GAL6,RBM47,IFI27,DAPK1,PRRG4,PDGFC,PARP9,LAMP3,CXCL11,DSE,IL18,BCL2A1,FAM20C,PRKAR2B,HERC5,SIGLEC1,ATF3;;;;;;;;;;;;;;;;protein binding (21), extracellular region (11), cytoplasm (10)
M166;TBA;TBA (M166);17;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M166.htm;FMO3,PDGFRA,AMOTL2,GHR,PDGFRB,OLFML3,CHRDL1,ECM2,CHL1,NNMT,GFRA1,TNC,C1S,IGF2 /// INS-IGF2,C7,OSMR,ABCA8;;;;;;;;;;;;;;;;protein binding (12), extracellular region (8), integral to membrane (7)
M167;enriched in cell cycle;enriched in cell cycle (M167);15;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M167.htm;BCL2L1,PPP2R1A,GSPT1,EHMT2,SESN3,MAD1L1,CDC34,TGFB1,PSMD3,AKT1,DNM2,FLNA,TSC2,RBM38,STRADB;;;;;;[Chaussabel.v2]M3.1;0;0;82;4;;;;;;protein binding (13), nucleus (13), cytoplasm (11)
M168;enriched in dendritic cells;enriched in dendritic cells (M168);19;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M168.htm;CLEC10A,B3GNT5,PGD,JAG1,FCER1A,EMILIN2,CLEC5A,CA2,CTSB,FAM20C,ADAM9,RRAGD,TACSTD2,CTSL1,IL1R1,GGTA1,DAB2,CAPG,AGPAT9;;;;;;;;;;;;;;;;protein binding (11), membrane (8), cytoplasm (7)
M169;mitosis (TF motif CCAATNNSNNNGCG);mitosis (TF motif CCAATNNSNNNGCG) (M169);16;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M169.htm;PCNA,SMC1A,TMPO,ORC4L,NOC3L,CASP8AP2,XPO1,CETN3,NUP37,UPF3B,ORC3L,NIF3L1,PMS1,ACTR6,ARMC1,ACTL6A;KEGG_CELL_CYCLE;0;0;128;4;;;;;;CCAATNNSNNNGCG_UNKNOWN;0;0;45;4;protein binding (10), nucleus (9), cytoplasm (7)
M170;TBA;TBA (M170);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M170.htm;LPHN2,GHR,EFEMP1,ECM2,GNG12,ELTD1,IL33,VGLL3,CHL1,GPR116,MPDZ,ABCA8;;;;;;;;;;;;;;;;protein binding (9), plasma membrane (8), integral to membrane (6)
M171;heme biosynthesis (I);heme biosynthesis (I) (M171);11;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M171.htm;HMBS,HEMGN,AHSP,ALAD,E2F2,CPOX,ALAS2,TMOD1,PLEK2,FECH,GATA1;BIOCARTA_AHSP_PATHWAY;0;0;13;7;[Chaussabel.v2]M2.3;0;0;71;5;GATA_Q6;0;0;161;3;protein binding (6), porphyrin metabolic process (5), heme biosynthetic process (5)
M172;enriched for TF motif TTCNRGNNNNTTC;enriched for TF motif TTCNRGNNNNTTC (M172);10;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M172.htm;CXCL3,EGR3,FOSB,GJB2,PLAU,NRIP3,NR4A3,EDN1,AG2,PHLDA2;[PID]AP-1 transcription factor network;0;0;66;3;;;;;;HSF_Q6;0;0;113;5;protein binding (5), sequence-specific DNA binding transcription factor activity (3), regulation of transcription, DNA-dependent (3)
M173;erythrocyte differentiation;erythrocyte differentiation (M173);14;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M173.htm;ETV1,FHL2,NTF3,DMD,KLF1,BPGM,TRIM10,EPB42,MYH10,HMBS,FEV,GFRA3,LYL1,GATA1;;;;;;[Chaussabel.v2]M2.3;0;0;71;5;GATA_C;0;0;236;14;protein binding (9), nucleus (7), cytoplasm (7)
M174;TBA;TBA (M174);24;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M174.htm;TSN,MUDENG,SRP9,SEC63,ANP32E,MATR3,EED,SMARCA5,PANK3,SACM1L,RNF138,CUL5,MORF4L2,ZBED5,MDFIC,BMI1,PCNP,TMX1,ZBTB11,TNFAIP8,SEP15,CCNC,RNF6,BZW1;;;;;;;;;;;EGR_Q6;0;0;212;7;protein binding (18), nucleus (14), cytoplasm (10)
M175;cell development;cell development (M175);13;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M175.htm;EPHB2,SFRP2,GREM1,AXIN2,ASCL2,CDX2,IHH,COL5A1,SATB2,GAS1,CTHRC1,IRX3,COL11A1;;;;;;;;;;;;;;;;protein binding (9), multicellular organismal development (7), extracellular region (6)
M176;TBA;TBA (M176);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M176.htm;GJA1,IGF1,AQP1,FRZB,DNASE1L3,IGFBP3,SNAI2,CXCL12,C7,ALDH1A3;;;;;;;;;;;;;;;;protein binding (6), extracellular region (5), nucleus (4)
M177.0;TBA;TBA (M177.0);34;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M177.0.htm;STX1A,ZNF234,CCR2,ZNF780A,ZFP3,TNFRSF12A,C20orf94,RNF170,HIC1,ZNF167,PPARGC1B,VKORC1L1,ZNF573,DUSP4,PPP1R16B,LOC100131067,ZNF559,FAM135A,ZMYM1,ATG4C /// CTR9,NR4A3,ATP10D,GIMAP8,IL1RAP,GIMAP4,GLCE,GIMAP6,GIMAP1,ZNF623,CX3CR1,NRIP3,BBS10,C15orf48,CSRP2BP;;;;;;;;;;;;;;;;nucleus (15), zinc ion binding (11), protein binding (11)
M177.1;TBA;TBA (M177.1);15;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M177.1.htm;ZNF623,NCRNA00183,C20orf94,CX3CR1,TMOD2,NR4A3,ZNF485,VKORC1L1,CCR2,ZNF573,FOSL1,KIAA1919,GIMAP6,ZFP3,LOC100131067;;;;;;;;;;;HNF4ALPHA_Q6;0;0;202;4;regulation of transcription, DNA-dependent (6), nucleus (6), DNA binding (6)
M178;enriched for promoter motif NATCACGTGAY (putative SREBF1 targets);enriched for promoter motif NATCACGTGAY (putative SREBF1 targets) (M178);10;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M178.htm;ARHGEF12,NGFRAP1,SOCS2,CAMK2D,PRKCE,KIT,AKAP12,PNOC,GEM,BLNK;;;;;;;;;;;SREBP1_01;0;0;136;6;protein binding (8), cytoplasm (8), signal transduction (5)
M179;enriched for TF motif PAX3;enriched for TF motif PAX3 (M179);10;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M179.htm;TRMT11,TNFAIP8,NUP54,USP1,CASP8AP2,BMI1,FAM35A,PURA,PMS1,RANBP6;;;;;;[Chaussabel.v2]M4.7;0;0;100;3;PAX3_B;0;0;65;4;protein binding (7), nucleus (6), cytoplasm (5)
M180;TBA;TBA (M180);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M180.htm;OSTM1,SIRT1,NPTN,CHUK,HIF1A,ROCK1,SYNJ1,ACSL4,TCF12,ATF2,IREB2;;;;;;;;;;;HEN1_01;0;0;157;3;protein binding (10), cytoplasm (6), nucleus (5)
M181;nucleotide metabolism;nucleotide metabolism (M181);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M181.htm;CTPS,ATIC,PAICS,RRM2,RRM1,GART,CAD,ADSL,PFAS,GMPS;KEGG_PURINE_METABOLISM;0;0;159;8;;;;;;;;;;;nucleobase, nucleoside and nucleotide metabolic process (10), cytosol (10), cytoplasm (7)
M182;enriched in DNA interacting proteins;enriched in DNA interacting proteins (M182);16;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M182.htm;STIL,DNAJC9,STMN1,CCDC99,SUV39H1,TAF5,BLM,ACAT1,YWHAH,POLD3,KIAA0494,RRM1,ALS2CR4,PPIL5,TFDP1,DONSON;;;;;;;;;;;HMGIY_Q6;0;0;187;5;protein binding (9), nucleus (7), cytoplasm (6)
M183;TBA;TBA (M183);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M183.htm;FXYD3,CDX1,EHF,KLF5,GMDS,LAD1,PKP3,TMEM45B,TRIM29,GALNT3;;;;;;;;;;;VDR_Q6;0;0;193;4;protein binding (6), nucleus (5), sequence-specific DNA binding transcription factor activity (4)
M184.0;TBA;TBA (M184.0);18;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M184.0.htm;CDKN2B,GPR144,BMP4,DLG4,ACVR1C,ARHGEF4,FOXO4,CSF3,MAP3K10,MAP2K7,MYOCD,FOXL1,TRPM4,APLP1,COL16A1,GP1BB,WNT11,RGMA;;;;;;;;;;;;;;;;protein binding (12), cytoplasm (9), plasma membrane (8)
M184.1;TBA;TBA (M184.1);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M184.1.htm;ADAMTSL2,CDKN2B,DLG4,CARD10,PSD,INS,MAP3K10,WNT11,FOXL1,TRPM4,MAPK8IP2;;;;;;;;;;;;;;;;protein binding (9), cytoplasm (7), signal transduction (4)
M185;TBA;TBA (M185);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M185.htm;HDAC2,NPTN,DLD,HPRT1,TCF12,PRNP,RB1,CTR9,SYNJ1,ATG5,RNF6,FNDC3A,PTPN11,BNIP2;;;;;;;;;;;;;;;;protein binding (13), cytoplasm (9), nucleus (6)
M186;TBA;TBA (M186);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M186.htm;PDLIM7,ELAVL3,EVX1,SOX15,CPEB3,GP1BB,TCF15,YBX1 /// YBX1P2,PSD,ARMC9,GRIN1;;;;;;;;;;;E2A_Q2;0;0;182;5;protein binding (7), multicellular organismal development (4), cytoplasm (4)
M187;metabolism in mitochondria, peroxisome;metabolism in mitochondria, peroxisome (M187);12;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M187.htm;SLC10A2,SLC28A1,CYP4A11,PRODH2,SLC2A2,LOC100422737,AGXT2,LOC100130232,GLYAT,CYP4A22,EHHADH,ACMSD;KEGG_FATTY_ACID_METABOLISM;0;0;42;3;;;;;;;;;;;membrane (5), mitochondrion (4), plasma membrane (3)
M188;TBA;TBA (M188);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M188.htm;LCN2,BPI,CARD11,OLFM4,SYTL2,PLCXD2,RNF144A,ATP8B4,CEACAM8,KIF21A;;;;;;;;;;;;;;;;protein binding (7), cytoplasm (4), plasma membrane (3)
M189;extracellular region cluster (GO);extracellular region cluster (GO) (M189);16;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M189.htm;CCL2,SEPP1,BMP2,ENG,CCL18,MMP28,HSPG2,CD34,MMP19,ECM1,CMTM8,NPY,CHI3L2,CCL23,CD5L,GH1;;;;;;;;;;;;;;;;extracellular space (13), extracellular region (13), protein binding (6)
M190;TBA;TBA (M190);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M190.htm;PPP1CC,BUB3,HAUS3,BMI1,CCNG1,OSM,EREG,IL1A,IL1B,CD2AP,USP16;;;;;;;;;;;;;;;;protein binding (7), cell division (6), nucleus (5)
M191;transmembrane transport (II);transmembrane transport (II) (M191);18;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M191.htm;SLC19A2,SIRT1,AXIN2,NUP54,KCNK5,MDFIC,ATP8A1,SLC35A3,ACSL5,SPNS3,SLC26A3,ATP11C,HEPH,ATP2C2,CUL5,KCNQ1,SLC12A2,CFTR;;;;;;;;;;;;;;;;membrane (13), transmembrane transport (11), integral to membrane (11)
M192;TBA;TBA (M192);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M192.htm;TGFB1,OGDH,PRMT1,G6PD,DEAF1,ILK,TLN1,MAP1S,NR1H2,NAPA,ARHGDIA,NBEAL2;;;;;;[Chaussabel.v2]M7.1;0;0;180;3;;;;;;protein binding (10), cytoplasm (9), cytosol (7)
M193;TBA;TBA (M193);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M193.htm;XK,NFIA,CTTN,C6orf192,ANKH,ATP1B2,SPTB,MGLL,PLEK2,GMPR,PBX1;;;;;;[Chaussabel.v2]M9.33;0;0;31;3;EGR1_01;0;0;200;6;protein binding (7), plasma membrane (5), cytoplasm (5)
M194;TBA;TBA (M194);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M194.htm;SMC1A,XPO1,ADNP,NOC3L,CETN3,NUP37,TXNDC9,TTC35,MTO1,PPP2R5C,ATF1,CRNKL1,CTCF,ARMC1;;;;;;;;;;;SPZ1_01;0;0;189;4;protein binding (11), nucleus (10), binding (6)
M195;muscle contraction, SRF targets;muscle contraction, SRF targets (M195);12;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M195.htm;LOC728264,MYH11,CNN1,ACTG2,PGM5,DES,MRGPRF,DES /// FAM48A,MYOCD,COL1A1,PLN,LMOD1;;;;;;;;;;;SRF_Q5_01;0;0;191;6;protein binding (8), cytoskeleton (5), cytoplasm (5)
M196;platelet activation - actin binding;platelet activation - actin binding (M196);17;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M196.htm;ITGB3,ITGB5,WASF3,ITGA2B,MPL,TPM4,PROS1,TGFB2,TPM1,THBS1,ACSBG1,ABLIM3,MFAP3L,ARHGAP6,HSPC159,ASAP2,PDE5A;KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM;0;0;85;6;[Chaussabel.v2]M1.1;0;0;86;8;;;;;;protein binding (9), cytoplasm (8), platelet activation (6)
M197;TBA;TBA (M197);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M197.htm;LPHN2,PLSCR4,WWTR1,NOVA1,TANC1,ELTD1,NR2F2,LDB2,GUCY1A3,FLRT2,ARHGAP29,NRP1,MPDZ,YAP1;;;;;;;;;;;MEIS1BHOXA9_01;0;0;110;4;protein binding (11), plasma membrane (5), nucleus (5)
M198;TBA;TBA (M198);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M198.htm;CEBPB,MRVI1,PDLIM7,LST1,CCNJL,PISD,TECPR2,XPO6,TSEN34,PHC2,LYN,CPPED1;;;;;;[Chaussabel.v2]M3.2;0;0;138;4;;;;;;protein binding (8), nucleus (6), cytoplasm (6)
M199;platelet activation & blood coagulation;platelet activation & blood coagulation (M199);13;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M199.htm;PROS1,LY6G6D /// LY6G6F,GP1BB /// SEPT5,SH3BGRL2,PCSK6,VWF,GP1BA,PRKAR2B,GP9,GP5,GP6,EGF,TTC7B;KEGG_ECM_RECEPTOR_INTERACTION;0;0;84;5;[Chaussabel.v2]M1.1;0;0;86;6;;;;;;protein binding (9), blood coagulation (8), platelet activation (7)
M200;antigen processing and presentation;antigen processing and presentation (M200);11;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M200.htm;HLA-DPB1,CD1D,LOC100294224,WDFY4,LOC100294318,HLA-DPA1,LOC100294317,HLA-DMB,METTL7A,HLA-DQA2,HLA-DMA;KEGG_ASTHMA;0;0;30;5;[Chaussabel.v2]M8.83;0;0;11;3;;;;;;protein binding (7), membrane (7), plasma membrane (6)
M201;TBA;TBA (M201);18;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M201.htm;MYH10,NFIA,ABCG2,C17orf99,SLC14A1,PDGFA,ANKH,TSPAN5,PAQR9,ARHGEF12,TMOD1,HEPACAM2,TGM2,TNXA /// TNXB,CDH1,C2orf88,ABCC13,PBX1;;;;;;[Chaussabel.v2]M2.3;0;0;71;5;ACAWYAAAG_UNKNOWN;0;0;85;5;protein binding (8), membrane (8), integral to membrane (7)
M202;enriched in extracellular matrix & associated proteins;enriched in extracellular matrix & associated proteins (M202);12;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M202.htm;PDGFRA,SFRP4,TWIST1,CCDC80,PCDH7,PCOLCE,GLT8D2,GAS1,PRRX1,FBLN1,CALD1,LUM;;;;;;;;;;;GATA1_04;0;0;195;4;protein binding (8), extracellular region (5), plasma membrane (4)
M203;TBA;TBA (M203);13;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M203.htm;PHTF2,AGL,RCN2,EEA1,ATF1,MAP3K7,ZBTB41,ATP11C,C12orf29,IKZF5,MBNL2,C12orf23,ATF2;;;;;;;;;;;;;;;;nucleus (7), protein binding (6), zinc ion binding (5)
M204.0;chaperonin mediated protein folding (I);chaperonin mediated protein folding (I) (M204.0);14;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M204.0.htm;CCT8,ATIC,CCT2,CCT3,NOP56,CCT7,CCT4,CCT5,HSPD1,SUCLG1,HSPE1,SSBP1,FBXW2,CCT6A;;;;;;;;;;;HSF_Q6;0;0;113;5;cytoplasm (10), unfolded protein binding (9), nucleotide binding (9)
M204.1;chaperonin mediated protein folding (II);chaperonin mediated protein folding (II) (M204.1);10;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M204.1.htm;CCT8,PFDN5,PFDN4,CCT2,CCT3,CCT7,CCT4,CCT5,CCT6A,VBP1;;;;;;;;;;;HSF_Q6;0;0;113;3;unfolded protein binding (10), protein folding (10), cellular protein metabolic process (10)
M205;TBA;TBA (M205);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M205.htm;SIRT1,BAG4,RNF111,RPS6KB1,CHUK,RB1,ZFAND6,RAPGEF6,BMPR2,ARFGEF2,AKAP11;BIOCARTA_HIVNEF_PATHWAY;0;0;58;3;;;;;;HNF4_01;0;0;200;3;protein binding (10), cytoplasm (9), nucleus (6)
M206;Wnt signaling pathway;Wnt signaling pathway (M206);14;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M206.htm;LOXL2,LAMC1,ANTXR1,SFRP4,FRZB,MAP1B,YAP1,CHL1,PMP22,KITLG,CXCL12,NRP1,SOX4,PDZRN3;;;;;;;;;;;;;;;;protein binding (11), extracellular region (8), plasma membrane (6)
M207;TBA;TBA (M207);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M207.htm;LRP2,SMG6,RAB26,NPY5R,SLC2A2,SLC22A2,SERPINF2,SLC6A13,ATP7B,RIMS3;;;;;;;;;;;;;;;;protein binding (6), plasma membrane (6), integral to membrane (6)
M208;TBA;TBA (M208);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M208.htm;SCAI,HACE1,APP,HOXA7,HOXB9,JMY,ARHGAP5,CCL23,NKX2-1,TUBE1;;;;;;;;;;;;;;;;protein binding (7), cytoplasm (6), nucleus (5)
M209;lysosome;lysosome (M209);10;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M209.htm;GNS,CTSB,GM2A,PSAP,CD68,CTSZ,CTSL1,CTSL2,SORT1,FUCA1;KEGG_LYSOSOME;0;0;121;10;;;;;;;;;;;lysosome (8), protein binding (5), proteolysis (4)
M210;extracellular matrix, collagen;extracellular matrix, collagen (M210);32;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M210.htm;COL10A1,TIMP3,COL11A1,TIMP1,SPARCL1,MFAP5,MFAP4,MFAP2,LAMB1,DCN,PODN,ADAMTS1,MGP,TGFB1I1,COL8A2,SERPINA1,EFEMP1,COMP,EFEMP2,COL4A1,TNC,SFRP2,EMILIN1,OMD,COL14A1,C1QA,CTGF,ADAMTS12,PXDN,COL6A3,CTHRC1,COL12A1;;;;;;;;;;;;;;;;extracellular region (31), protein binding (26), proteinaceous extracellular matrix (20)
M211;TBA;TBA (M211);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M211.htm;NEK7,ADD3,RNF11,SLC25A46,PLEKHF2,CMPK1,MDFIC,BMI1,RAP1B,CCNG1,PRKRIR;;;;;;;;;;;LEF1_Q2;0;0;175;5;protein binding (7), cytoplasm (7), nucleus (6)
M212;purine nucleotide biosynthesis;purine nucleotide biosynthesis (M212);12;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M212.htm;CHCHD3,ATIC,MTHFD1,RUVBL2,CCT3,CCT7,IMPDH2,PAICS,FKBP3,ADSL,PFAS,GMPS;KEGG_PURINE_METABOLISM;0;0;159;6;[Chaussabel.v2]M3.5;0;0;149;3;;;;;;protein binding (9), cytosol (9), purine nucleotide biosynthetic process (7)
M213;regulation of transcription, transcription factors;regulation of transcription, transcription factors (M213);21;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M213.htm;CREBZF,KIAA1109,C14orf138,PTBP2,KIAA1468,STAG2,MED23,ZNF700,ZDHHC17,DUSP10,SDCCAG1,NCRNA00201,PPP1R12A,BDP1,FMR1,CLK1,ARID4B,CCNT2,CLK4,BTAF1,SFRS12;;;;;;;;;;;IRF_Q6;0;0;177;7;nucleus (14), protein binding (11), regulation of transcription, DNA-dependent (6)
M214;TBA;TBA (M214);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M214.htm;TGFBR1,RP2,SOS2,C6orf211,CHUK,PIK3CG,ZFAND6,STXBP3,ATP11B,TMEM30A,SPAST,LPGAT1;KEGG_CHRONIC_MYELOID_LEUKEMIA;0;0;73;4;;;;;;;;;;;protein binding (9), nucleotide binding (6), ATP binding (6)
M215;small GTPase mediated signal transduction;small GTPase mediated signal transduction (M215);16;signaling;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M215.htm;TAGAP,RAC2,FGD3,ARAP1,RHOH,GMIP,VAV1,ARHGAP30,HMHA1,ARHGAP15,ARHGDIB,ARHGAP9,ARHGAP25,ARHGDIA,ARHGAP4,RHOG;;;;;;;;;;;;;;;;small GTPase mediated signal transduction (16), regulation of small GTPase mediated signal transduction (16), cytosol (16)
M216;respiratory electron transport chain (mitochondrion);respiratory electron transport chain (mitochondrion) (M216);12;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M216.htm;NDUFA7,NDUFB7,COX6A1,UQCRB,NDUFB10,ATP5J,UQCR10,ATP5H,NDUFS6,COX7B,COX7C,COX6C;KEGG_PARKINSONS_DISEASE;0;0;133;12;[Chaussabel.v2]M6.2;0;0;156;3;;;;;;respiratory electron transport chain (12), mitochondrion (12), mitochondrial inner membrane (12)
M217;TBA (source: B cells);TBA (source: B cells) (M217);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M217.htm;FMO3,PLSCR4,PROS1,FLRT2,MXRA5,ABI3BP,TMEM47,CDH5,LUM,MEOX2;;;;;;;;;;;;;;;;protein binding (8), membrane (4), integral to membrane (4)
M218;TBA;TBA (M218);15;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M218.htm;PREPL,ATG4C /// CTR9,C3orf1,GTF2H1,ALG6,SLC35B3,POT1,HPS5,SLC35A5,C11orf73,RPE,PMS1,ELP3,ACADM,CSRP2BP;;;;;;;;;;;SREBP1_01;0;0;136;4;protein binding (7), nucleus (5), cytoplasm (5)
M219;respiratory electron transport chain (mitochondrion);respiratory electron transport chain (mitochondrion) (M219);18;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M219.htm;UQCRC2,COX5A,COX5B,UQCR10,COX7B,CYC1,UQCRB,UQCRQ,UQCRH,COX8A,ATP5L,COX6B1,UQCRFS1,UQCRC1,COX6A1,COX7C,COX6C,COX7A2L;KEGG_CARDIAC_MUSCLE_CONTRACTION;0;0;80;17;[Chaussabel.v2]M5.13;0;0;177;5;ER_Q6_02;0;0;204;5;respiratory electron transport chain (18), mitochondrion (18), mitochondrial inner membrane (18)
M220;TBA;TBA (M220);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M220.htm;SFN,SPDEF,KIAA1324,KCNC3,TFAP2A,SOX9,GRIN2B,AR,REEP1,NOS1AP;;;;;;;;;;;;;;;;protein binding (8), nucleus (5), sequence-specific DNA binding transcription factor activity (4)
M221;TBA;TBA (M221);16;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M221.htm;LOC145845,RNF17,ACCN5,ESCO2,LOC100290132,LBX1,IFNA7,POU4F2,IFNA4,FLJ37543,CCDC144C /// LOC100134159,LOC100287227 /// LOC100292133,NCRNA00119,TRIM49,CCDC26,MST1 /// MST1P2 /// MST1P9;;;;;;;;;;;HNF3B_01;0;0;175;4;protein binding (4), nucleus (4), metal ion binding (3)
M222;heme biosynthesis (II);heme biosynthesis (II) (M222);13;biological process;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M222.htm;HMBS,SPTA1,ALAD,RFESD,TRIM10,RHCE /// RHD,RHCE,CPOX,PPOX,KLF1,UROD,BLVRB,YPEL4;KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM;0;0;41;6;;;;;;GATA_C;0;0;236;6;porphyrin metabolic process (6), cytoplasm (6), heme biosynthetic process (5)
M223;enriched in T cells (II);enriched in T cells (II) (M223);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M223.htm;SLC38A1,HOPX,CD40LG,DENND2D,TC2N,PLEKHF1,LRRN3,CLEC2D,FGFBP2,LBH,TRGC2,DPP4,LOC439949;;;;;;;;;;;;;;;;protein binding (7), plasma membrane (5), nucleus (4)
M224;transmembrane and ion transporters (II);transmembrane and ion transporters (II) (M224);11;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M224.htm;NTF3,DMD,GRIK3,SLC24A2,CACNA1F,JPH2,SLC4A3,CALCA,SLC1A6,KCNA5,ATP7B;;;;;;;;;;;FOX_Q2;0;0;172;3;protein binding (9), plasma membrane (8), transmembrane transport (6)
M225;metabolism of steroids;metabolism of steroids (M225);10;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M225.htm;GALNT14,ALPK2,UGT2A3,LOC100422737,UGT2B15,MIOX,UGT2B17,PKHD1,HAVCR1,UGT2B28;KEGG_ASCORBATE_AND_ALDARATE_METABOLISM;0;0;25;5;;;;;;;;;;;membrane (7), integral to membrane (7), transferase activity, transferring hexosyl groups (4)
M226;proteasome;proteasome (M226);12;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M226.htm;TAF9,RAN,PSMD14,NUP37,PSMA2,PSMA3,PSMA6,PSMC6,PSMA4,PSMA5,PSMC2,POLR2K;KEGG_PROTEASOME;0;0;48;8;[Chaussabel.v2]M5.6;0;0;141;4;TCF11MAFG_01;0;0;161;3;viral reproduction (12), protein binding (11), nucleus (11)
M227;translation initiation;translation initiation (M227);10;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M227.htm;ETFA,EIF3J,PSMD14,METTL5,NDUFA8,COPS5,EIF4H,NUP37,EIF2S1,EIF2S2;;;;;;[Chaussabel.v2]M5.6;0;0;141;3;;;;;;protein binding (7), translational initiation (5), translation initiation factor activity (5)
M228;olfactory receptors;olfactory receptors (M228);13;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M228.htm;OR7C2,OR7E24,LOC100132247 /// LOC348162 /// LOC613037 /// LOC728888 /// LOC729602 /// LOC729978 /// NPIPL2 /// NPIPL3,OR2C3,LOC100290132,IFNA7,CCDC144C /// LOC100134159,LOC100286993,OR7D2,OR2H1,MST1 /// MST1P2 /// MST1P9,LOC284861,GUCA1C;;;;;;;;;;;;;;;;sensory perception of smell (5), response to stimulus (5), receptor activity (5)
M229;TBA;TBA (M229);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M229.htm;MIER3,CAND1,CDKN2AIP,AEBP2,CRY1,DYNLT3,BMI1,RAB18,MAPK6,CCNC,PTBP2;;;;;;;;;;;TITF1_Q3;0;0;184;5;protein binding (9), nucleus (9), regulation of transcription, DNA-dependent (7)
M230;cell cycle, mitotic phase;cell cycle, mitotic phase (M230);12;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M230.htm;HACE1,AHCTF1,SMC3,TP53BP2,CENPC1,CD28,JMY,NAE1,MIS12,TTC19,TUBE1,RANBP2;;;;;;;;;;;;;;;;protein binding (10), cytoplasm (8), nucleus (7)
M231;respiratory electron transport chain (mitochondrion);respiratory electron transport chain (mitochondrion) (M231);11;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M231.htm;ATP5C1,NDUFAB1,COX5A,NDUFB4,NDUFB3,NDUFB1,NDUFS3,NDUFA8,ATP5L,UQCRFS1,NDUFB11;KEGG_OXIDATIVE_PHOSPHORYLATION;0;0;135;10;[Chaussabel.v2]M5.10;0;0;230;4;;;;;;respiratory electron transport chain (11), mitochondrion (11), mitochondrial inner membrane (11)
M232;enriched for TF motif TNCATNTCCYR;enriched for TF motif TNCATNTCCYR (M232);13;TF targets;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M232.htm;TBCK,VPS41,RAD51C,GTF2H1,TCHP,MEN1,HDDC3,SMARCAL1,PDE6D,RAD50,TTC1,ELP4,HSD17B4;;;;;;;;;;;TNCATNTCCYR_UNKNOWN;0;0;93;5;protein binding (9), nucleus (5), cytoplasm (4)
M233;TBA;TBA (M233);15;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M233.htm;MAP3K10,BMP4,ELAVL3,PRDM8,HOXD10,JPH2,CRYBB3,PCDHB11,BOK,PLA2G2D,GFRA4,C8orf39,NCRNA00105,FOXN1,HOXB13;;;;;;;;;;;USF_01;0;0;194;4;protein binding (8), nucleus (5), regulation of transcription, DNA-dependent (4)
M234;transcription elongation, RNA polymerase II;transcription elongation, RNA polymerase II (M234);14;biological process;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M234.htm;MEA1,NDUFA3,AURKAIP1,TCEB2,NDUFB11,NDUFB10,POLR2E,UQCR10,POLR2L,BOLA2 /// BOLA2B,UQCRQ,MIF,POLR2I,POLR2J;KEGG_HUNTINGTONS_DISEASE;0;0;185;8;;;;;;;;;;;protein binding (6), nucleus (6), mitochondrion (6)
M235;mitochondrial cluster;mitochondrial cluster (M235);19;location;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M235.htm;DNAJA3,ALG8,EIF2B3,PUS7,C3orf1,WDR92,TCHP,C11orf73,NDUFA8,C14orf126,SMARCAL1,MCCC2,ALDH6A1,POP5,HIBCH,HIBADH,ALDH18A1,TMEM218,ACADM;KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION;0;0;44;5;;;;;;;;;;;mitochondrion (10), protein binding (6), mitochondrial matrix (6)
M236;TBA;TBA (M236);14;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M236.htm;GTF2E1,BET1,PAQR8,FTSJD1,ZNF189,CRNKL1,POLR1B,UTP14C,ZKSCAN4,GIMAP4,EXOSC3,GIMAP6,C17orf80,VPRBP;;;;;;;;;;;TNCATNTCCYR_UNKNOWN;0;0;93;4;nucleus (7), protein binding (6), metal ion binding (4)
M237;golgi membrane (II);golgi membrane (II) (M237);17;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M237.htm;ARFIP1,ZDHHC17,GALNT7,C3orf58,GOLPH3L,PAQR3,RAB33B,C1GALT1C1,GOLT1B,SLC35B3,RAB21,PNPLA8,SGMS1,SLC35A3,SLC35A5,COPB2,GOPC;;;;;;;;;;;;;;;;Golgi membrane (15), membrane (14), Golgi apparatus (13)
M238;respiratory electron transport chain (mitochondrion);respiratory electron transport chain (mitochondrion) (M238);17;location;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M238.htm;NDUFA6,NDUFA4,NDUFA2,NDUFA3,ATP5J2,NDUFB6,NDUFB2,UQCRQ,NDUFC2,ATP5I,ATP5O,NDUFA11,UQCRH,NDUFS7,NDUFS8,NDUFS4,ATP5D;KEGG_OXIDATIVE_PHOSPHORYLATION;0;0;135;17;[Chaussabel.v2]M6.2;0;0;156;5;;;;;;respiratory electron transport chain (17), mitochondrion (17), mitochondrial inner membrane (17)
M239;enriched in calcium signaling proteins;enriched in calcium signaling proteins (M239);15;signaling;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M239.htm;SLITRK6,FLJ35409,FAM196A,EPHB1,DMD,C1orf114,SPOCK3,GRIA4,TRPC3,LOC441666,CAPS2,LOC642426,MYOZ2,F11,LOC338739;;;;;;;;;;;HNF3B_01;0;0;175;4;protein binding (7), plasma membrane (5), membrane (5)
M240;chromosome Y linked;chromosome Y linked (M240);17;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M240.htm;XIST,DPF3,UTY,NCRNA00185,CYorf15B,CYorf15A,MAP7D2,TTTY15,TSIX,KAL1,USP9Y,MYOCD,KDM5D,BCORL2,RGMA,PRKY,DDX3Y;;;;;;;;;;;;;;;;protein binding (5), nucleus (5), nucleic acid binding (3)
M241;TBA;TBA (M241);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M241.htm;PAN2,CCNL2,TBC1D3F,TBC1D3H,LOC440354,AHSA2,LOC641298,TBC1D3C,LOC595101,CALCA;;;;;;;;;;;;;;;;intracellular (5), regulation of Rab GTPase activity (3), protein binding (3)
M242;TBA;TBA (M242);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M242.htm;SNX14,SNX13,STRN3,MAP3K2,ACAP2,MED1,RASA2,REL,DYRK1A,CREBBP,FBXW7;;;;;;;;;;;;;;;;protein binding (11), nucleus (7), cytoplasm (5)
M243;TBA;TBA (M243);12;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M243.htm;BCAP31,NDUFB9,TMEM160,NDUFB7,TBCB,DDT,SCAND1,APRT,PRELID1,SRM,PSMB3,TUFM;;;;;;;;;;;;;;;;protein binding (6), mitochondrion (5), nucleus (4)
M244;TBA;TBA (M244);13;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M244.htm;ADCY1,ITGB1BP3,TTLL9,C21orf89,DKFZp779M0652,ADCY8,TLE6,TRIM17,HTR6,CES4,CAMK2N1,AVPR2,GNG8;;;;;;;;;;;;;;;;plasma membrane (6), synaptic transmission (4), protein binding (4)
M245;translation initiation factor 3 complex;translation initiation factor 3 complex (M245);13;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M245.htm;EIF3H,UXT,EIF3K,PHB2,EEF1G,EIF3D,EIF3E,EIF3F,EEF1G /// TUT1,LOC100294182 /// RPL3,EIF3G,EEF1B2,FBL;;;;;;[Chaussabel.v2]M5.5;0;0;245;6;;;;;;protein binding (11), translation (8), gene expression (8)
M246;TBA;TBA (M246);16;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M246.htm;RUNDC2C,RUNDC2B,C14orf82,SNAPC1,RPA4,C15orf5,LOC100128439,PMEPA1,RASSF6,SLC5A8,LOC145474,LOC644852,POLR2J4,KIAA0754,PLIN5,KIAA1659;;;;;;;;;;;;;;;;plasma membrane (2), nucleus (2), nucleoplasm (2)
M247;enriched in nuclear pore complex interacting proteins;enriched in nuclear pore complex interacting proteins (M247);14;molecular function;partial;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M247.htm;IL17A,LOC613037,FAM153A,LOC729978,ANKRD34C,LIN28A,LOC728888,HRH4,LOC348162,CNTNAP3B,EFCAB5,NPIPL3,NPIPL2,LOC729602;;;;;;;;;;;;;;;;protein binding (4), integral to membrane (2), inflammatory response (2)
M248;TBA;TBA (M248);11;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M248.htm;C11orf2,C17orf70,SSNA1,C1orf86,RASSF7,E4F1,C12orf10,FBXL15,TBL3,ALDH16A1,CCDC85B;;;;;;;;;;;;;;;;nucleus (7), protein binding (6), cytoplasm (4)
M249;TBA;TBA (M249);10;;;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M249.htm;ANKRD44,TIMP4,LOC339524,HS2ST1,CIDEC,CD300LG,LY75,LEP,PLIN4,C11orf63;;;;;;;;;;;;;;;;protein binding (4), receptor activity (2), plasma membrane (2)
M250;spliceosome;spliceosome (M250);12;molecular function;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/M250.htm;SNRPE,SNRPD3,SNRPD1,LSM3,LSM5,SNRPG,RBMX,SF3B14,SNRPA,SNRPF,MAGOH,SNRPD2;KEGG_SPLICEOSOME;0;0;128;12;[Chaussabel.v2]M5.13;0;0;177;3;;;;;;protein binding (11), nucleus (11), RNA splicing (11)
S0;T cell surface signature;T cell surface signature (S0);27;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S0.htm;NPDC1,ANKH,LAG3,CD6,CD2,CD320,SLC37A3,C6orf129,NDFIP2,CXCR6,SIT1,SIRPG,ICOS,CD28,SLC38A1,TMEM106C,PTPRCAP,FLT3LG,C12orf23,GIMAP2,LRRN3,CLEC2D,CD3E,ITM2A,GPR171,MAL,CD3G;;;;;;;;;;;;;;;;integral to membrane (20), membrane (16), plasma membrane (15)
S1;NK cell surface signature;NK cell surface signature (S1);48;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S1.htm;PDGFRB,TNFSF11,IL12RB2,TNFSF14,SLC7A5,ADRB2,S1PR5,ATP9A,TIE1,PTGDR,NCAM1,KLRF1,ELOVL6,IL18RAP,KIR2DS4,KIR2DS5,KIR2DS2,KIR2DS3,PTGER2,KIR2DS1,SLCO4C1,GPR82,TGFBR3,KLRC3,ENPP5,IL18R1,NCR1,DLL1,FASLG,KIR3DL1,KIR2DL5A,KIR3DL3,IL2RB,TMEM64,CX3CR1,KLRK1,CD97,SYNGR3,RARRES3,KIT,KIR2DL3,KIR2DL2,KIR2DL1,ATP8B4,SLAMF7,PVRIG,GPR114,HAVCR2;KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY;0;0;137;13;;;;;;;;;;;integral to membrane (33), plasma membrane (30), protein binding (26)
S2;B cell surface signature;B cell surface signature (S2);169;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S2.htm;SSPN,AVPR1A,KCNE4,TSPAN13,CD37,HEPACAM2,GYPA,SEMA4B,EGF,GPR37,MS4A1,C11orf87,USH2A,PPP1R3A,OR12D3,POPDC3,DCC,SLC12A1,GP5,CDH5,SLITRK6,HLA-DPB1,PCDHA3,TRHDE,FAIM3,CD22,GHR,LY9,TAS2R13,FLRT2,TPTE,TMEM100,GYPE,PLD4,ADAM7,KCNMB3,FCRL3,GPR6,CSPG4,SYT2,ROBO2,NRXN3,FREM2,TRPC1,GPR116,TMEM47,SCN3A,NPY1R,LPPR4,NOX4,PDZK1IP1,CCR9,CD200,GABBR1,EDNRB,GJC1,LHCGR,PCDHB8,NT5E,PDPN,PCDHB4,CLDN8,LRRTM4,HRH4,NMBR,NCAM2,GRM5,TM4SF20,IL5RA,JAM2,JAM3,IL28RA,MC3R,F2RL3,ASTN1,MOGAT2,SLC26A7,SLC24A1,TACR3,CR2,IL13RA2,IMPG2,LRRC19,TMEFF2,ITM2C,PCDH10,BTC,GPR98,AGTR1,CD19,TMEM133,CD72,UGT2A3,OR11A1,TLR10,CSMD1,TRPC7,CCR6,GABRA5,PLP1,CD79B,CLCA4,CD79A,CNR1,EPHA3,SLC30A10,SGCE,BTLA,CHRNB4,PCDHB10,PCDHB16,PCDHB15,PCDHB14,CADM2,GPR85,SLC6A15,GPR87,NLGN1,SLC13A1,CELSR1,OR1E1,GABRB1,CD180,ADAM28,CXADR,TAAR2,HHLA2,SLC17A6,CNTNAP3,SLC6A16,HLA-DOA,HLA-DOB,HLA-DPA1,ABCA8,CD52,OR2J2,CHL1,TMEM156,SLC5A7,P2RX5,OR2W1,LPHN3,LPHN2,HLA-DRA,LRP1B,CXCR5,ABCB4,FCRL1,FCRL2,PCDH20,FCRL5,KCND2,SLC44A5,ITGB6,NLGN4Y,FCGR2B,CHRM2,PTH2R,HEPH,CD24,PCDH9,BAI3,PTPRR,SELE,FAM26F,SCN1A,HTR1E,PTPRK,HLA-DMA;;;;;;;;;;;;;;;;integral to membrane (140), plasma membrane (123), protein binding (93)
S3;Plasma cell surface signature;Plasma cell surface signature (S3);24;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S3.htm;PPAP2C,KCNG2,SLC5A4,CAV1,TEK,TMEM37,GP1BB,SLC16A14,ICAM2,SLC44A1,CCR10,CHRM1,CLPTM1L,KCNN3,HM13,GPR25,KCNH1,TXNDC15,SDC1,DRD4,KRTCAP2,TRAM2,SCARB2,AMIGO3;;;;;;;;;;;;;;;;integral to membrane (18), protein binding (14), plasma membrane (14)
S4;Monocyte surface signature;Monocyte surface signature (S4);94;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S4.htm;FXYD6,KCNE3,AMICA1,CD33,CD36,C5AR1,FCGR1B,APCDD1,LTBR,PECAM1,CYBRD1,GPR109B,PLXND1,FCAR,DYSF,FPR1,FPR2,HLA-DRB4,CSF3R,CCR1,C19orf59,TLR2,CD163,TLR1,TLR4,TLR5,TREM1,TNFSF12,CLEC12B,CLEC12A,EMR1,EMR2,LPPR2,IL1R2,MARCO,LILRB3,LILRB2,LILRB1,SLC11A1,MGAM,C10orf54,TMEM71,SLC46A2,VNN2,KCNQ1,FCGR2A,TNFRSF1B,MBOAT7,CD93,ITGAM,SIRPB1,GPER,CD4,TNFRSF10B,CCR2,CD302,PTAFR,MCTP1,FCER1A,S1PR3,P2RY13,SLC7A7,AGTRAP,CECR6,IL6R,ASGR1,ASGR2,TMEM154,LRP1,LRRC33,C1orf162,TMTC2,ABCA1,STEAP4,SPNS1,P2RX1,VSTM1,BRI3,NFAM1,TMEM55A,PYCARD,FCGRT,GLIPR1,MFSD1,SLC24A4,PTGIR,MS4A6A,P2RY2,SLC40A1,SLC16A3,ANO10,PTPRE,SIGLEC9,GPR133;;;;;;;;;;;;;;;;integral to membrane (69), plasma membrane (64), protein binding (50)
S5;DC surface signature;DC surface signature (S5);82;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S5.htm;CSF2RB,TM2D2,CD1E,CD1B,PPAP2B,SLC7A8,CD1A,KMO,CD58,LRFN4,CCRL2,SIGLEC1,CD151,ADAM12,TM7SF4,SLC36A1,PDCD1LG2,PSEN2,GPR137B,C19orf28,TMEM158,PTGFRN,IL1R1,SLC6A6,SPINT2,LRP11,FZD5,TSPAN33,DIRC2,ALCAM,CD83,GJB2,GPNMB,ABHD12,CD9,EMP1,TFRC,HLA-DQB1,LHFPL2,TACSTD2,COLEC12,JAG1,SUCNR1,TMEM51,TGFA,SLC38A6,ITPRIPL2,CALCRL,CLDN23,ATP1B2,GRINA,FPR3,RAMP1,ATP1B1,TREM2,SRD5A3,SLC41A2,FAM70A,LAMP2,ABCC3,DENND1B,P2RY6,NRP1,NRP2,CXCL16,PRRG4,CRIM1,GPR157,OLR1,CD274,SDC2,SLCO2B1,SLC7A11,ADAM9,ABCA6,MSR1,ACE,AGPAT3,SLAMF8,SLC1A3,HLA-DQA1,TNFRSF11A;;;;;;;;;;;;;;;;integral to membrane (68), plasma membrane (53), membrane (52)
S6;CD4 T cell surface signature Th1-stimulated;CD4 T cell surface signature Th1-stimulated (S6);9;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S6.htm;F2R,TMEM200A,C6orf129,GPR19,LAG3,NDFIP2,TSPAN5,SV2A,GPR114;;;;;;;;;;;;;;;;integral to membrane (9), membrane (7), protein binding (4)
S7;CD4 T cell surface signature Th2-stimulated;CD4 T cell surface signature Th2-stimulated (S7);13;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S7.htm;SLC37A3,GPR15,CD28,CLDND1,TMEM200A,SLC4A7,IL17RB,ITM2A,GPR171,SIT1,C6orf129,MAL,CD3G;;;;;;;;;;;;;;;;membrane (9), integral to membrane (8), plasma membrane (7)
S8;Naive B cell surface signature;Naive B cell surface signature (S8);54;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S8.htm;LGR4,KCNE4,TSPAN13,UGT2A3,CD37,TRHR,CNTNAP3,PPAPDC1B,CCR6,CD200,GABBR1,EDNRB,GHSR,CLCA4,CNR1,CD72,P2RY14,BTLA,HRH4,PCDHB4,SLC38A11,C4orf34,PCDHB16,CXCR4,TMEM56,GRM5,PCDH20,CDH5,KCNJ16,JAM2,ITGB6,CHRNB4,PCDHB14,SLC24A1,SLC26A3,HTR1E,MUC15,OR1G1,IL13RA2,KCNMB3,FCRL3,IMPG2,GPR6,HHLA2,TAS2R7,HVCN1,NRXN3,FAM26F,HLA-DOA,BTC,SELE,GABRE,GPR116,HLA-DMA;;;;;;;;;;;;;;;;integral to membrane (48), plasma membrane (38), protein binding (29)
S9;Memory B cell surface signature;Memory B cell surface signature (S9);37;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S9.htm;SSPN,CD52,CLDN17,SORCS3,EPHA3,OR11A1,TNFRSF17,CSMD1,NOX4,CHL1,CCR9,NCAM2,LINGO1,TACR3,JAM3,NKAIN4,CADM2,PCDHA3,TRHDE,NLGN1,FCGR2B,NLGN4Y,TAS2R10,ASTN1,GRAMD1C,GYPA,TNFRSF13B,CXADR,ADAM2,PTPRR,NPY1R,GJC1,ITM2C,FREM2,ABCA8,SCN1A,GLP2R;;;;;;;;;;;;;;;;integral to membrane (28), plasma membrane (27), protein binding (19)
S10;Resting dendritic cell surface signature;Resting dendritic cell surface signature (S10);75;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S10.htm;CLEC10A,CD1E,CD1B,CD1C,SLC7A8,CD1A,SERINC5,IGSF6,TREM2,TSPAN15,CCRL2,CD151,ADAM12,TM7SF4,SLC36A1,LRFN4,GPR137B,STAB1,CD86,IL1R2,IL1R1,IFNGR1,FZD1,FCER1A,FZD5,DIRC2,PSEN2,CSF1R,GPNMB,ABHD12,PTGFRN,KMO,EMP1,HLA-DQB1,LHFPL2,SLC1A3,CCDC90A,LPCAT2,JAG1,PLXDC2,SUCNR1,TMEM51,SFXN3,SPINT2,SLC38A6,ITPRIPL2,ENG,MFSD1,TTYH3,SRD5A3,TACSTD2,TMEM144,FAM70A,ABCC3,PLXND1,DENND1B,ATP1B1,P2RY6,NRP1,SLC27A3,SLCO2B1,ITGAX,SLC26A11,CRIM1,CLDN23,PLD3,SLC7A11,CD9,ADAM9,ABCA6,ACE,SLAMF8,HLA-DMA,AGPAT9,CH25H;;;;;;;;;;;;;;;;integral to membrane (64), membrane (52), plasma membrane (42)
S11;Activated (LPS) dendritic cell surface signature;Activated (LPS) dendritic cell surface signature (S11);37;immune;complete;http://www.interactivefigures.com/meni/btm416_annotation/btmdata/S11.htm;CSF2RB,ANTXR2,IFI27,SLC31A2,TNFSF13B,TGFA,LY75,CD80,CD58,TMCC3,SLCO5A1,F11R,TTYH2,ITGB8,RNF144B,SGPP2,CALCRL,NINJ1,CD40,IL3RA,LAMP2,TMEM140,PDCD1LG2,KITLG,SLC43A2,NRP2,PRRG4,IL13RA1,SLC41A2,GPR157,IFI6,CD274,LRRC32,ELOVL7,COLEC12,EREG,SIGLEC1;;;;;;;;;;;;;;;;integral to membrane (32), plasma membrane (24), protein binding (23)