diff --git a/chia/_tests/core/mempool/test_mempool_manager.py b/chia/_tests/core/mempool/test_mempool_manager.py
index e5505d9db568..582c536049fb 100644
--- a/chia/_tests/core/mempool/test_mempool_manager.py
+++ b/chia/_tests/core/mempool/test_mempool_manager.py
@@ -18,6 +18,8 @@
 from chia.full_node.mempool_check_conditions import get_name_puzzle_conditions, mempool_check_time_locks
 from chia.full_node.mempool_manager import (
     MEMPOOL_MIN_FEE_INCREASE,
+    QUOTE_BYTES,
+    QUOTE_EXECUTION_COST,
     MempoolManager,
     TimelockConditions,
     can_replace,
@@ -1943,8 +1945,8 @@ async def get_coin_records(coin_ids: Collection[bytes32]) -> List[CoinRecord]:
 
 
 TEST_FILL_RATE_ITEM_COST = 144_720_020
-QUOTE_BYTE_COST = 2 * DEFAULT_CONSTANTS.COST_PER_BYTE
-QUOTE_EXECUTION_COST = 20
+TEST_COST_PER_BYTE = 12_000
+TEST_BLOCK_OVERHEAD = QUOTE_BYTES * TEST_COST_PER_BYTE + QUOTE_EXECUTION_COST
 
 
 @pytest.mark.anyio
@@ -1962,8 +1964,8 @@ async def get_coin_records(coin_ids: Collection[bytes32]) -> List[CoinRecord]:
         # Here we set the block cost limit to twice the test items' cost - 1,
         # so we expect only one of the two test items to get included in the block.
         # NOTE: The cost difference here is because get_conditions_from_spendbundle
-        # does not include the overhead to make a block (quote byte cost  + quote runtime cost).
-        (TEST_FILL_RATE_ITEM_COST * 2 - 1, 1, TEST_FILL_RATE_ITEM_COST + QUOTE_BYTE_COST + QUOTE_EXECUTION_COST),
+        # does not include the block overhead.
+        (TEST_FILL_RATE_ITEM_COST * 2 - 1, 1, TEST_FILL_RATE_ITEM_COST + TEST_BLOCK_OVERHEAD),
     ],
 )
 async def test_fill_rate_block_validation(
diff --git a/chia/full_node/mempool_manager.py b/chia/full_node/mempool_manager.py
index 1c73e2c2804f..4387e89e746e 100644
--- a/chia/full_node/mempool_manager.py
+++ b/chia/full_node/mempool_manager.py
@@ -119,6 +119,11 @@ class NewPeakItem:
     conds: SpendBundleConditions
 
 
+# For block overhead cost calculation
+QUOTE_BYTES = 2
+QUOTE_EXECUTION_COST = 20
+
+
 class MempoolManager:
     pool: Executor
     constants: ConsensusConstants
@@ -158,7 +163,11 @@ def __init__(
         self.nonzero_fee_minimum_fpc = 5
 
         BLOCK_SIZE_LIMIT_FACTOR = 0.7
-        self.max_block_clvm_cost = uint64(self.constants.MAX_BLOCK_COST_CLVM * BLOCK_SIZE_LIMIT_FACTOR)
+        # We need to deduct the block overhead, which consists of the wrapping
+        # quote opcode's bytes cost as well as its execution cost.
+        BLOCK_OVERHEAD = QUOTE_BYTES * self.constants.COST_PER_BYTE + QUOTE_EXECUTION_COST
+
+        self.max_block_clvm_cost = uint64(self.constants.MAX_BLOCK_COST_CLVM * BLOCK_SIZE_LIMIT_FACTOR - BLOCK_OVERHEAD)
         self.max_tx_clvm_cost = (
             max_tx_clvm_cost if max_tx_clvm_cost is not None else uint64(self.constants.MAX_BLOCK_COST_CLVM // 2)
         )