diff --git a/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-ciemss-drilldown.vue b/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-ciemss-drilldown.vue
index 6a9c8e87c9..306e85f3f0 100644
--- a/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-ciemss-drilldown.vue
+++ b/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-ciemss-drilldown.vue
@@ -25,7 +25,9 @@
 								:disabled="_.isEmpty(node.outputs[0].value)"
 							/>
 							<tera-pyciemss-cancel-button class="mr-auto" :simulation-run-id="cancelRunId" />
-							<Button :disabled="isRunDisabled" label="Run" icon="pi pi-play" @click="runOptimize" />
+							<div v-tooltip="runButtonMessage">
+								<Button :disabled="isRunDisabled" label="Run" icon="pi pi-play" @click="runOptimize" />
+							</div>
 						</span>
 					</div>
 
@@ -48,7 +50,10 @@
 						/>
 					</section>
 					<section class="form-section">
-						<h5>Intervention policy</h5>
+						<h5>
+							Intervention policy
+							<i v-if="!isInterventionReady" v-tooltip="interventionReadyTooltip" class="pi pi-exclamation-circle" />
+						</h5>
 						<template v-for="(cfg, idx) in knobs.interventionPolicyGroups">
 							<tera-static-intervention-policy-group
 								v-if="
@@ -94,6 +99,12 @@
 								:calendar-settings="getCalendarSettingsFromModel(model)"
 								v-model="knobs.endTime"
 							/>
+							<i
+								class="pi pi-exclamation-circle"
+								style="max-width: fit-content"
+								v-if="!isEndTimeValid"
+								v-tooltip="endTimeTooltip"
+							/>
 						</div>
 						<div class="input-row">
 							<div class="label-and-input">
@@ -405,7 +416,6 @@ import { logger } from '@/utils/logger';
 import { nodeMetadata } from '@/components/workflow/util';
 import { WorkflowNode } from '@/types/workflow';
 import TeraSliderPanel from '@/components/widgets/tera-slider-panel.vue';
-
 import TeraNotebookError from '@/components/drilldown/tera-notebook-error.vue';
 import { flattenInterventionData, getInterventionPolicyById } from '@/services/intervention-policy';
 import TeraCheckbox from '@/components/widgets/tera-checkbox.vue';
@@ -512,16 +522,41 @@ const datasetId = computed(() => {
 
 const displayOptimizationResultMessage = ref(true);
 
-const isRunDisabled = computed(() => {
+// Checks for disabling run button:
+const isCriteriaReady = computed(() => {
 	const activeConstraintGroups = knobs.value.constraintGroups.filter((ele) => ele.isActive);
-	return (
-		activeConstraintGroups.length === 0 ||
-		!activeConstraintGroups.every((ele) => ele.targetVariable) ||
-		knobs.value.interventionPolicyGroups.length === 0 ||
-		activePolicyGroups.value.length <= 0
-	);
+	return activeConstraintGroups.length !== 0 && activeConstraintGroups.every((ele) => ele.targetVariable);
 });
 
+const isInterventionReady = computed(() => activePolicyGroups.value.length > 0);
+
+const isEndTimeValid = computed(() =>
+	activePolicyGroups.value.every((ele) => {
+		if (
+			[OptimizationInterventionObjective.startTime, OptimizationInterventionObjective.paramValueAndStartTime].includes(
+				ele.optimizationType
+			)
+		) {
+			return ele.endTime <= knobs.value.endTime;
+		}
+		return true;
+	})
+);
+
+const isRunDisabled = computed(() => !isCriteriaReady.value || !isInterventionReady.value || !isEndTimeValid.value);
+
+const criteriaReadyTooltip = computed(() => (!isCriteriaReady.value ? 'Success criteria must be filled in. \n' : ''));
+const interventionReadyTooltip = computed(() =>
+	!isInterventionReady.value ? 'Must contain at least one active intervention policy.\n' : ''
+);
+const endTimeTooltip = computed(() =>
+	!isEndTimeValid.value ? 'End time must be greater than or equal to all intervention policy end times. \n' : ''
+);
+
+const runButtonMessage = computed(() =>
+	isRunDisabled.value ? `${criteriaReadyTooltip.value} ${interventionReadyTooltip.value} ${endTimeTooltip.value}` : ''
+);
+
 const presetType = computed(() => {
 	if (
 		knobs.value.numSamples === speedValues.numSamplesToSimModel &&
diff --git a/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-criterion-group-form.vue b/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-criterion-group-form.vue
index 3fa23350a7..548c2af493 100644
--- a/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-criterion-group-form.vue
+++ b/packages/client/hmi-client/src/components/workflow/ops/optimize-ciemss/tera-optimize-criterion-group-form.vue
@@ -30,6 +30,7 @@
 				placeholder="Select"
 				@update:model-value="emit('update-self', config)"
 			/>
+			<i v-if="_.isEmpty(config.targetVariable)" class="pi pi-exclamation-circle" v-tooltip="requiredTooltip" />
 			is
 			<Dropdown
 				class="toolbar-button"
@@ -44,6 +45,7 @@
 			/>
 			a threshold of
 			<tera-input-number v-model="config.threshold" @update:model-value="emit('update-self', config)" />
+			<i v-if="!config.threshold" class="pi pi-exclamation-circle" v-tooltip="requiredTooltip" />
 			at
 			<Dropdown
 				:options="[
@@ -56,8 +58,11 @@
 				@update:model-value="emit('update-self', config)"
 			/>
 			in
-			<tera-input-number v-model="config.riskTolerance" @update:model-value="emit('update-self', config)" />% of
-			simulated outcomes
+			<tera-input-number v-model="config.riskTolerance" @update:model-value="emit('update-self', config)" /><i
+				v-if="!config.riskTolerance"
+				class="pi pi-exclamation-circle"
+				v-tooltip="requiredTooltip"
+			/>% of simulated outcomes
 		</div>
 		<div v-else class="section-row">
 			Ensure <b>{{ config.targetVariable }}</b> is <b>{{ config.isMinimized ? 'below' : 'above' }}</b> a threshold of
@@ -84,7 +89,7 @@ const props = defineProps<{
 const emit = defineEmits(['update-self', 'delete-self']);
 
 const config = ref<Criterion>(_.cloneDeep(props.criterion));
-
+const requiredTooltip = 'Required';
 const isEditing = ref<boolean>(false);
 
 const onEdit = () => {