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Entering this text into the "Results and Conclusion Summary" of the data submission form causes it to crash:
Emerging evidence implicates microbiome involvement in the development of pancreatic cancer (PaCa). We investigated whether increases in circulating microbial-related metabolites are associated with PaCa risk by applying metabolomics profiling to 172 sera collected within five years prior to PaCa diagnosis and 863 matched non-case sera from participants in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cohort. Using a subset of specimens from seven PLCO centers, a three-marker microbial-related metabolite panel was developed to assess 5-year risk of PaCa. The panel was validated using samples from three different PLCO centers as well as a separate cohort of newly-diagnosed PaCa cases and controls. The addition of five non-microbial metabolites further improved 5-year risk prediction of PaCa. The combined metabolite panel was complementary with CA19-9 and individuals with a combined metabolite panel plus CA19-9 score in the top 2.5th percentile had absolute 5-year risk estimates of >13%. The risk prediction model based on circulating microbial- and non-microbial metabolites provides a potential tool to identify individuals at high-risk of pancreatic cancer and who would benefit from surveillance and/or from potential cancer interception strategies.
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🐛 Describe the Bug
Entering this text into the "Results and Conclusion Summary" of the data submission form causes it to crash:
📜 How To Reproduce
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🔎 Expected Behavior
It should go through.
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