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Optimal Design Theory

This repo is based on Biostat 279 taught by Dr. Weng Kee Wong at UCLA.

Topics include:

  • Optimal allocation rule in randomized clinical trials.
  • Elements of convex analysis and differentiation.
  • Equivalence theorem and Fedorov's algorithm.
  • D, G, A, E, c, D_A and D_s optimal designs.
  • Metaheuristics including particle swarm optimization and cuckoo search.