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Synonymous variants with no variant scores #12

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afrubin opened this issue Mar 5, 2018 · 0 comments
Open

Synonymous variants with no variant scores #12

afrubin opened this issue Mar 5, 2018 · 0 comments

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@afrubin
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afrubin commented Mar 5, 2018

In some cases for variants with low counts or high dropout rates, a synonymous variant gets a score when there is no score for a corresponding nucleotide variant. Two examples from the BRCA1 example dataset are p.Val10Asp and p.Ile20Ter.

There should be an option to automatically filter these variants out of the default /main/synonymous/scores table (and consequently shown as missing in sequence-function maps).

Thanks to Adebola Adeniran for raising this issue via email.

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