diff --git a/README.md b/README.md index ce4a8af..11e174d 100644 --- a/README.md +++ b/README.md @@ -19,7 +19,7 @@ Clair3 is a germline small variant caller for long-reads. Clair3 makes the best Clair3 is the 3rd generation of [Clair](https://github.com/HKU-BAL/Clair) (the 2nd) and [Clairvoyante](https://github.com/aquaskyline/Clairvoyante) (the 1st). -A short preprint describing Clair3's algorithms and results is at [bioRxiv](https://www.biorxiv.org/content/10.1101/2021.12.29.474431v1). +Clair3 is published at [Nature Computational Science](https://rdcu.be/c1TPa), and available as a preprint at [bioRxiv](https://www.biorxiv.org/content/10.1101/2021.12.29.474431v2). ---- @@ -592,4 +592,4 @@ Please find more details about the training data and links at [Training Data](do Clair3 supports both VCF and GVCF output formats. Clair3 uses VCF version 4.2 specifications. Specifically, Clair3 adds a `P` INFO tag to the results called using a pileup model, and a `F` INFO tag to the results called using a full-alignment model. -Clair3 outputs a GATK-compatible GVCF format that passes GATK's `ValidateVariants` module. Different from DeepVariant that uses `<*>` to represent any possible alternative allele, Clair3 uses ``, the same as GATK. \ No newline at end of file +Clair3 outputs a GATK-compatible GVCF format that passes GATK's `ValidateVariants` module. Different from DeepVariant that uses `<*>` to represent any possible alternative allele, Clair3 uses ``, the same as GATK.