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Single-Cell-Omics

This is a repository for my efforts in analysing Single-Cell Omics data!

Paper-implementation (Triple Negative Breast Cancer)

In this project I have tried to implement the paper "Unraveling Heterogeneity of Tumor Cells and Microenvironment and Its Clinical Implications for Triple Negative Breast Cancer" by Ke Jiang et al. (2021) PMID: 33854958.

I have mostly tried to follow the methodology mentioned in the paper in a coarse way, with use of different tools and functions in case the original ones used in the paper have become defunct or if I found a tool or function that is decreasing the number of steps, and is easier to implement and understand.

The results that I received are quite different from the ones in the paper which might be because of difference in the way I performed cleaning and Quality control on the data, followed by usage of different parameters and the arguments passed for the various functions used throughout.