IsoSolve is a Python module realizing an integrative framework for isotope labeling measurements. It can provide both symbolic and numeric solutions for integrating and consolidating heterogeneous measurements, e.g. NMR and MS measuring ¹³C labeling, to cite the most wide spread ones. This integrative framework helps to
- clarify and improve the coverage of the isotopic space;
- evaluate the complementarity and redundancy of different techniques;
- consolidate isotopic datasets;
- design experiments, and
- guide future analytical developments.
This framework can be applied to any labeled element, isotopic tracer, metabolite, and analytical platform.
IsoSolve is available as a Python library with a command line interface. It is one of the routine tools that we use at the MetaSys team and MetaToul platform in isotopic studies of metabolic systems.
A paper on this subject is under preparation.
If you have an idea on how we could improve IsoSolve please submit a new issue to our GitHub issue tracker.