diff --git a/pkgs/development/interpreters/python/python-packages-base.nix b/pkgs/development/interpreters/python/python-packages-base.nix
index 19c230a0b94ec..5569606f113aa 100644
--- a/pkgs/development/interpreters/python/python-packages-base.nix
+++ b/pkgs/development/interpreters/python/python-packages-base.nix
@@ -14,26 +14,40 @@ let
 
   # Derivations built with `buildPythonPackage` can already be overridden with `override`, `overrideAttrs`, and `overrideDerivation`.
   # This function introduces `overridePythonAttrs` and it overrides the call to `buildPythonPackage`.
+  #
+  # Overridings specified through `overridePythonAttrs` will always be applied
+  # before those specified by `overrideAttrs`, even if invoked after them.
   makeOverridablePythonPackage =
     f:
-    lib.mirrorFunctionArgs f (
+    let
+      mirrorArgs = lib.mirrorFunctionArgs f;
+    in
+    mirrorArgs (
       origArgs:
       let
         args = lib.fix (
           lib.extends (_: previousAttrs: {
             passthru = (previousAttrs.passthru or { }) // {
-              overridePythonAttrs = newArgs: makeOverridablePythonPackage f (overrideWith newArgs);
+              inherit overridePythonAttrs;
             };
           }) (_: origArgs)
         );
         result = f args;
-        overrideWith = newArgs: args // (if pkgs.lib.isFunction newArgs then newArgs args else newArgs);
+
+        overrideWith = newArgs: args // lib.toFunction newArgs args;
+        overridePythonAttrs = mirrorArgs (newArgs: makeOverridablePythonPackage f (overrideWith newArgs));
+
+        # Change the result of the function call by applying g to it
+        overrideResult = g: makeOverridablePythonPackage (mirrorArgs (args: g (f args))) origArgs;
       in
       if builtins.isAttrs result then
         result
+        // lib.optionalAttrs (result ? overrideAttrs) {
+          overrideAttrs = fdrv: overrideResult (drv: drv.overrideAttrs fdrv);
+        }
       else if builtins.isFunction result then
         {
-          overridePythonAttrs = newArgs: makeOverridablePythonPackage f (overrideWith newArgs);
+          inherit overridePythonAttrs;
           __functor = self: result;
         }
       else
diff --git a/pkgs/test/overriding.nix b/pkgs/test/overriding.nix
index 9ccc84e033560..14b67f44fb7c2 100644
--- a/pkgs/test/overriding.nix
+++ b/pkgs/test/overriding.nix
@@ -7,6 +7,15 @@
 let
   tests = tests-stdenv // tests-go // tests-python;
 
+  # We are testing the overriding result of these packages without building them.
+  pkgsAllowingBroken = pkgs.extend (
+    finalAttrs: previousAttrs: {
+      config = previousAttrs.config // {
+        allowBroken = true;
+      };
+    }
+  );
+
   tests-stdenv =
     let
       addEntangled =
@@ -184,13 +193,49 @@ let
 
   tests-python =
     let
-      p = pkgs.python3Packages.xpybutil.overridePythonAttrs (_: {
-        dontWrapPythonPrograms = true;
-      });
+      inherit (pkgsAllowingBroken.python3Packages) pip;
+      applyOverridePythonAttrs =
+        p:
+        p.overridePythonAttrs (_: {
+          dontWrapPythonPrograms = true;
+        });
+      revertOverridePythonAttrs =
+        p:
+        p.overridePythonAttrs (_: {
+          dontWrapPythonPrograms = false;
+        });
+      checkOverridePythonAttrs = p: !lib.hasInfix "wrapPythonPrograms" p.postFixup;
+      overrideAttrsFooBar =
+        drv:
+        drv.overrideAttrs (
+          finalAttrs: previousAttrs: {
+            FOO = "a";
+            BAR = finalAttrs.FOO;
+          }
+        );
+      checkAttrsFooBar = drv: drv.FOO == "a" && drv.BAR == "a";
     in
     {
       overridePythonAttrs = {
-        expr = !lib.hasInfix "wrapPythonPrograms" p.postFixup;
+        expr = checkOverridePythonAttrs (applyOverridePythonAttrs pip);
+        expected = true;
+      };
+      overridePythonAttrs-nested = {
+        expr = revertOverridePythonAttrs (applyOverridePythonAttrs pip) == pip;
+        expected = true;
+      };
+      overrideAttrs-overridePythonAttrs-test-overrideAttrs = {
+        expr = checkAttrsFooBar (applyOverridePythonAttrs (overrideAttrsFooBar pip));
+        expected = true;
+      };
+      overrideAttrs-overridePythonAttrs-test-overridePythonAttrs = {
+        expr = checkOverridePythonAttrs (applyOverridePythonAttrs (overrideAttrsFooBar pip));
+        expected = true;
+      };
+      overrideAttrs-overridePythonAttrs-test-commutation = {
+        expr =
+          (applyOverridePythonAttrs (overrideAttrsFooBar pip))
+          == (overrideAttrsFooBar (applyOverridePythonAttrs pip));
         expected = true;
       };
     };