diff --git a/pkgs/development/python-modules/django-nose/default.nix b/pkgs/development/python-modules/django-nose/default.nix
deleted file mode 100644
index 2f3d1da6fdf63..0000000000000
--- a/pkgs/development/python-modules/django-nose/default.nix
+++ /dev/null
@@ -1,32 +0,0 @@
-{
-  lib,
-  buildPythonPackage,
-  fetchPypi,
-  nose,
-  django,
-}:
-
-buildPythonPackage rec {
-  pname = "django-nose";
-  version = "1.4.7";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "a4885cd002d65fd2de96e2bb2563ef477c3fbe207009360c015fca5c3b5561b7";
-  };
-
-  # vast dependency list
-  doCheck = false;
-
-  propagatedBuildInputs = [
-    django
-    nose
-  ];
-
-  meta = with lib; {
-    description = "Provides all the goodness of nose in your Django tests";
-    homepage = "https://github.com/django-nose/django-nose";
-    license = licenses.bsd3;
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 49eec3d93d70f..8dfdaf30be6d9 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -131,6 +131,7 @@ mapAliases ({
   django-hijack-admin = throw "django-hijack-admin has been removed, since it is no longer compatible to django-hijack"; # added 2023-06-21
   django_modelcluster = django-modelcluster; # added 2022-04-02
   django_nose = django-nose; # added 2023-07-25
+  django-nose = throw "django-nose has been removed since it has not been maintained and there are no dependent packages"; # added 2024-05-21
   django_reversion = django-reversion; # added 2022-06-18
   django_polymorphic = django-polymorphic; # added 2022-05-24
   django_redis = django-redis; # added 2021-10-11
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 150965f1d2052..22d6c6cdb83d2 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -3276,8 +3276,6 @@ self: super: with self; {
 
   django-ninja = callPackage ../development/python-modules/django-ninja { };
 
-  django-nose = callPackage ../development/python-modules/django-nose { };
-
   django-oauth-toolkit = callPackage ../development/python-modules/django-oauth-toolkit { };
 
   django-otp = callPackage ../development/python-modules/django-otp { };