diff --git a/doc8/tests/test_checks.py b/doc8/tests/test_checks.py
index 1776dfe..79e0618 100644
--- a/doc8/tests/test_checks.py
+++ b/doc8/tests/test_checks.py
@@ -13,16 +13,14 @@
 #    WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the
 #    License for the specific language governing permissions and limitations
 #    under the License.
-
+import unittest
 import tempfile
 
-import testtools
-
 from doc8 import checks
 from doc8 import parser
 
 
-class TestTrailingWhitespace(testtools.TestCase):
+class TestTrailingWhitespace(unittest.TestCase):
     def test_trailing(self):
         lines = ["a b  ", "ab"]
         check = checks.CheckTrailingWhitespace({})
@@ -34,7 +32,7 @@ def test_trailing(self):
         self.assertIn(code, check.REPORTS)
 
 
-class TestTabIndentation(testtools.TestCase):
+class TestTabIndentation(unittest.TestCase):
     def test_tabs(self):
         lines = ["    b", "\tabc", "efg", "\t\tc"]
         check = checks.CheckIndentationNoTab({})
@@ -46,7 +44,7 @@ def test_tabs(self):
         self.assertIn(code, check.REPORTS)
 
 
-class TestCarriageReturn(testtools.TestCase):
+class TestCarriageReturn(unittest.TestCase):
     def test_cr(self):
         content = b"Windows line ending\r\nLegacy Mac line ending\r"
         content += (b"a" * 79) + b"\r\n" + b"\r"
@@ -62,7 +60,7 @@ def test_cr(self):
             self.assertIn(code, check.REPORTS)
 
 
-class TestLineLength(testtools.TestCase):
+class TestLineLength(unittest.TestCase):
     def test_over_length(self):
         content = b"""
 ===
@@ -169,7 +167,7 @@ def test_definition_term_length(self):
             self.assertEqual(0, len(errors))
 
 
-class TestNewlineEndOfFile(testtools.TestCase):
+class TestNewlineEndOfFile(unittest.TestCase):
     def test_newline(self):
         tests = [
             (1, b"testing"),
diff --git a/doc8/tests/test_main.py b/doc8/tests/test_main.py
index 00b6f93..c7681e3 100644
--- a/doc8/tests/test_main.py
+++ b/doc8/tests/test_main.py
@@ -3,9 +3,9 @@
 from mock import patch, MagicMock
 import os
 from io import StringIO
+import unittest
 import shutil
 import sys
-import testtools
 
 from doc8.main import main, doc8
 
@@ -145,7 +145,7 @@ def report(self):
         return ""
 
 
-class TestCommandLine(testtools.TestCase):
+class TestCommandLine(unittest.TestCase):
     """
     Test command line invocation
     """
@@ -181,7 +181,7 @@ def test_main__no_quiet_verbose__output_is_verbose(self):
         self.assertEqual(state, 1)
 
 
-class TestApi(testtools.TestCase):
+class TestApi(unittest.TestCase):
     """
     Test direct code invocation
     """
@@ -226,7 +226,7 @@ def test_doc8__verbose__verbose_overridden(self):
         self.assertEqual(result.total_errors, 2)
 
 
-class TestArguments(testtools.TestCase):
+class TestArguments(unittest.TestCase):
     """
     Test that arguments are parsed correctly
     """
diff --git a/mypy.ini b/mypy.ini
index 07afbee..d8f6a2c 100644
--- a/mypy.ini
+++ b/mypy.ini
@@ -6,6 +6,3 @@ ignore_missing_imports = True
 
 [mypy-stevedore]
 ignore_missing_imports = True
-
-[mypy-testtools]
-ignore_missing_imports = True
diff --git a/test-requirements.txt b/test-requirements.txt
index 48fd091..737a6b5 100644
--- a/test-requirements.txt
+++ b/test-requirements.txt
@@ -1,4 +1,3 @@
 mock # BSD
-nose # LGPL
-testtools # MIT
+pytest # MIT
 toml # MIT
diff --git a/tox.ini b/tox.ini
index a840e31..ce4b300 100644
--- a/tox.ini
+++ b/tox.ini
@@ -5,7 +5,7 @@ envlist = lint,py,docs,packaging
 [testenv]
 deps =
   -r{toxinidir}/test-requirements.txt
-commands = nosetests {posargs}
+commands = pytest {posargs}
 whitelist_externals =
   rm