From 3b002efa6bf51e951767d8a7749ebad563897cb8 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Tue, 20 Feb 2024 14:12:44 +0100
Subject: [PATCH 01/13] added docs features
---
docs/examples/setup_local_blast.md | 0
docs/installation/docker.md | 5 ----
.../installation/{pip.md => install_pyeed.md} | 8 +++----
docs/installation/setup_local_blast.md | 6 +++++
docs/{examples => quick_start}/alignments.md | 11 +++++++--
docs/{examples => quick_start}/basics.md | 0
docs/{examples => quick_start}/blast.md | 0
docs/{examples => quick_start}/clustering.md | 0
docs/quick_start/index.md | 20 ++++++++++++++++
docs/{examples => quick_start}/networks.md | 0
mkdocs.yml | 24 +++++++++++++------
11 files changed, 56 insertions(+), 18 deletions(-)
delete mode 100644 docs/examples/setup_local_blast.md
delete mode 100644 docs/installation/docker.md
rename docs/installation/{pip.md => install_pyeed.md} (88%)
create mode 100644 docs/installation/setup_local_blast.md
rename docs/{examples => quick_start}/alignments.md (91%)
rename docs/{examples => quick_start}/basics.md (100%)
rename docs/{examples => quick_start}/blast.md (100%)
rename docs/{examples => quick_start}/clustering.md (100%)
create mode 100644 docs/quick_start/index.md
rename docs/{examples => quick_start}/networks.md (100%)
diff --git a/docs/examples/setup_local_blast.md b/docs/examples/setup_local_blast.md
deleted file mode 100644
index e69de29b..00000000
diff --git a/docs/installation/docker.md b/docs/installation/docker.md
deleted file mode 100644
index 95506131..00000000
--- a/docs/installation/docker.md
+++ /dev/null
@@ -1,5 +0,0 @@
----
-icon: simple/docker
----
-
-# Installation with Docker
\ No newline at end of file
diff --git a/docs/installation/pip.md b/docs/installation/install_pyeed.md
similarity index 88%
rename from docs/installation/pip.md
rename to docs/installation/install_pyeed.md
index f94b3c2c..bfc1317e 100644
--- a/docs/installation/pip.md
+++ b/docs/installation/install_pyeed.md
@@ -1,7 +1,3 @@
----
-icon: simple/python
----
-
# Installation via `pip`
PyEED can be installed from Github via pip.
@@ -13,3 +9,7 @@ Alternatively, you can install the latest stable release from PyPI.
```bash
```
+
+
+# Installation with Docker
+
diff --git a/docs/installation/setup_local_blast.md b/docs/installation/setup_local_blast.md
new file mode 100644
index 00000000..81fbc55c
--- /dev/null
+++ b/docs/installation/setup_local_blast.md
@@ -0,0 +1,6 @@
+# Setup a Local BLAST Database
+
+This tutorial will guide you through the process of setting up a local BLAST database. This is useful if you have a large number of sequences that you need to search against, or if you want to search against a custom database.
+
+1. Hi
+2. Hello
\ No newline at end of file
diff --git a/docs/examples/alignments.md b/docs/quick_start/alignments.md
similarity index 91%
rename from docs/examples/alignments.md
rename to docs/quick_start/alignments.md
index 620b44ac..c62afabd 100644
--- a/docs/examples/alignments.md
+++ b/docs/quick_start/alignments.md
@@ -54,13 +54,20 @@ alignment = Alignment.from_sequences(list_of_sequences)
tem109 = ProteinInfo.from_ncbi("AAT46413.1")
# Create and run alignment
- alignment = PairwiseAlignment([tem1, tem109], aligner=PairwiseAligner)
+ alignment = PairwiseAlignment([tem1, tem109], aligner=PairwiseAligner, mode="local")
```
=== "Global Alignment"
``` py
from pyeed.core import ProteinInfo, PairwiseAlignment
- from pyeed.aligners import NeedlemanWunsch
+ from pyeed.aligners import PairwiseAligner
+
+ # Get two ProteinInfo objects
+ tem1 = ProteinInfo.from_ncbi("QGC48744.1")
+ tem109 = ProteinInfo.from_ncbi("AAT46413.1")
+
+ # Create and run alignment
+ alignment = PairwiseAlignment([tem1, tem109], aligner=PairwiseAligner, mode="global")
```
diff --git a/docs/examples/basics.md b/docs/quick_start/basics.md
similarity index 100%
rename from docs/examples/basics.md
rename to docs/quick_start/basics.md
diff --git a/docs/examples/blast.md b/docs/quick_start/blast.md
similarity index 100%
rename from docs/examples/blast.md
rename to docs/quick_start/blast.md
diff --git a/docs/examples/clustering.md b/docs/quick_start/clustering.md
similarity index 100%
rename from docs/examples/clustering.md
rename to docs/quick_start/clustering.md
diff --git a/docs/quick_start/index.md b/docs/quick_start/index.md
new file mode 100644
index 00000000..621031b8
--- /dev/null
+++ b/docs/quick_start/index.md
@@ -0,0 +1,20 @@
+---
+hide:
+ - navigation
+ - footer
+---
+
+# Quick Start
+
+
+
+- :material-walk: __[Basics]__ – How to work with sequence data
+- :octicons-search-16: __[Search Sequences]__ – How to search for individual sequences or search using BLAST
+- :fontawesome-solid-align-justify: __[Alignments]__ – How to make different alignments
+- :material-dots-grid: __[Networks]__ – How to construct sequence networks
+
+
+ [Basics]: basics.md
+ [Search Sequences]: blast.md
+ [Alignments]: alignments.md
+ [Networks]: networks.md
\ No newline at end of file
diff --git a/docs/examples/networks.md b/docs/quick_start/networks.md
similarity index 100%
rename from docs/examples/networks.md
rename to docs/quick_start/networks.md
diff --git a/mkdocs.yml b/mkdocs.yml
index 42471fad..8f20defd 100644
--- a/mkdocs.yml
+++ b/mkdocs.yml
@@ -2,26 +2,36 @@ site_name: PyEED Documentation
repo_url: https://github.com/PyEED/pyeed/
repo_name: PyEED/pyeed
site_url: https://pyeed.github.io/pyeed/
+site_author: Max Häußler
+
nav:
- 🏠 Home: index.md
- ⚡️ Quick Start:
- - The Sequence objects: examples/basics.md
- - Finding Sequences: examples/blast.md
- - Aligning Sequences: examples/alignments.md
- - Clustering Sequences: examples/clustering.md
- - Creating Sequence Networks: examples/networks.md
+ - quick_start/index.md
+ - The Sequence objects: quick_start/basics.md
+ - Finding Sequences: quick_start/blast.md
+ - Aligning Sequences: quick_start/alignments.md
+ - Clustering Sequences: quick_start/clustering.md
+ - Creating Sequence Networks: quick_start/networks.md
- 🔎 Use cases:
- Get an Overview over a Protein Family: usecases/usecase1.md
- ⬇️ Installation:
- - PIP: installation/pip.md
- - Docker: installation/docker.md
+ - Install PyEED: installation/install_pyeed.md
+ - Setup Local BLAST database: installation/setup_local_blast.md
theme:
name: material
logo: figs/pyeed.png
features:
+ - navigation.instant
+ - navigation.instant.progress
+ - navigation.instant.preview
+ - navigation.indexes
+ - navigation.footer
+
+ - content.action.view
- navigation.tabs
- navigation.sections
- toc.integrate
From 4f31b3956dd5b5717d508f1a8604cd00a01b1542 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Tue, 20 Feb 2024 17:22:53 +0100
Subject: [PATCH 02/13] refactored pairwise aligner
---
pyeed/aligners/pairwise.py | 84 ++++++----------------
pyeed/containers/abstract_container.py | 12 +++-
pyeed/core/alignment.py | 98 +++++++++++++++++++++-----
3 files changed, 116 insertions(+), 78 deletions(-)
diff --git a/pyeed/aligners/pairwise.py b/pyeed/aligners/pairwise.py
index d1cc57eb..c5852066 100644
--- a/pyeed/aligners/pairwise.py
+++ b/pyeed/aligners/pairwise.py
@@ -1,4 +1,3 @@
-from numpy import short
from pydantic import BaseModel, Field, validator
import sdRDM
from typing import Any, List, Optional
@@ -88,35 +87,6 @@ def align(self):
alignment_result = aligner.align(shorter_seq, longer_seq)[0]
- # aligned_sequences = [
- # Sequence(source_id=shorter_seq.source_id, sequence=alignment_result[0]),
- # Sequence(source_id=longer_seq.source_id, sequence=alignment_result[1]),
- # ]
-
- # gaps = alignment_result.counts().gaps
- # mismatches = alignment_result.counts().mismatches
- # identities = alignment_result.counts().identities
- # identity = identities / len(shorter_seq.sequence)
-
- # standard_numbering = StandardNumbering(
- # reference_id=shorter_seq.source_id,
- # numbered_id=longer_seq.source_id,
- # numbering=Alignment._get_numbering_string(
- # shorter_seq.sequence, longer_seq.sequence
- # ),
- # )
-
- # alignment = PairwiseAlignment(
- # input_sequences=[shorter_seq, longer_seq],
- # method=self.mode,
- # aligned_sequences=aligned_sequences,
- # standard_numberings=[standard_numbering],
- # score=alignment_result.score,
- # identity=identity,
- # gaps=gaps,
- # mismatches=mismatches,
- # )
-
return alignment_result
def _load_substitution_matrix(self) -> Any:
@@ -124,34 +94,26 @@ def _load_substitution_matrix(self) -> Any:
return substitution_matrices.load(self.substitution_matrix)
-
-# def multi_pairwise_alignment(
-# protien_infos: List[ProteinInfo],
-# mode: str = "global",
-# match: int = 1,
-# mismatch: int = -1,
-# gap_open: int = -1,
-# gap_extend: int = 0,
-# substitution_matrix: str = "None",
-# n_jobs: int = None,
-# ):
-# pairs = list(combinations(protien_infos, 2))
-
-# if n_jobs is None:
-# n_jobs = cpu_count()
-
-# alignments = Parallel(n_jobs=n_jobs, prefer="processes")(
-# delayed(pairwise_alignment)(
-# reference,
-# query,
-# mode,
-# match,
-# mismatch,
-# gap_open,
-# gap_extend,
-# substitution_matrix,
-# )
-# for reference, query in tqdm(pairs, desc="⛓️ Aligning sequences")
-# )
-
-# return alignments
+ # def align_multi_pairwise(self):
+ # n_jobs = cpu_count()
+
+ # pairs = list(combinations(protien_infos, 2))
+
+ # if n_jobs is None:
+ # n_jobs = cpu_count()
+
+ # alignments = Parallel(n_jobs=n_jobs, prefer="processes")(
+ # delayed(pairwise_alignment)(
+ # reference,
+ # query,
+ # mode,
+ # match,
+ # mismatch,
+ # gap_open,
+ # gap_extend,
+ # substitution_matrix,
+ # )
+ # for reference, query in tqdm(pairs, desc="⛓️ Aligning sequences")
+ # )
+
+ # return alignments
diff --git a/pyeed/containers/abstract_container.py b/pyeed/containers/abstract_container.py
index 5614a10a..aa8094a7 100644
--- a/pyeed/containers/abstract_container.py
+++ b/pyeed/containers/abstract_container.py
@@ -10,6 +10,8 @@
from docker.client import DockerClient
from docker.models.containers import Container
from docker.models.images import Image
+from docker.errors import DockerException
+
from pyeed.ncbi import seq_io
@@ -62,7 +64,15 @@ def __init__(self, **kwargs):
BaseModel.__init__(self, **kwargs)
super().__init__(**kwargs)
self._tempdir_path = tempfile.mkdtemp()
- self._client = docker.from_env()
+ self._client = self._initialize_docker_client()
+
+ def _initialize_docker_client(self) -> DockerClient:
+ try:
+ client = docker.from_env()
+ client.ping()
+ return client
+ except DockerException as e:
+ print(f"Docker is not running. Start the Docker application. {e}")
def get_image(self) -> Image:
"""Gets the image from Docker Hub. If the image is not found, it will be pulled."""
diff --git a/pyeed/core/alignment.py b/pyeed/core/alignment.py
index d469b853..6135bffb 100644
--- a/pyeed/core/alignment.py
+++ b/pyeed/core/alignment.py
@@ -1,10 +1,11 @@
-import re
import sdRDM
-
+from tqdm import tqdm
+from itertools import combinations
from typing import List, Optional, Union
from pydantic import Field, validator
from sdRDM.base.listplus import ListPlus
from sdRDM.base.utils import forge_signature, IDGenerator
+from Bio.Align import Alignment as BioAlignment
from pyeed.aligners.pairwise import PairwiseAligner
@@ -136,10 +137,10 @@ def add_to_standard_numberings(
def align(self, aligner: Union[AbstractContainer, PairwiseAligner], **kwargs):
if issubclass(aligner, AbstractContainer):
- self._container_align(aligner, **kwargs)
+ return self._container_align(aligner, **kwargs)
elif issubclass(aligner, PairwiseAligner):
- self._python_align(aligner, **kwargs)
+ return self._python_align(aligner, **kwargs)
else:
raise ValueError(
@@ -167,24 +168,89 @@ def _container_align(self, aligner: AbstractContainer, **kwargs):
self.apply_standard_numbering()
+ return self
+
def _python_align(self, aligner: PairwiseAligner, **kwargs):
+
if len(self.input_sequences) == 2:
- alignment_reuslt = aligner(
+
+ shorter_seq, longer_seq = sorted(
+ self.input_sequences, key=lambda x: len(x.sequence)
+ )
+ pairwise_aligner = aligner(
sequences=[
- self.input_sequences[0].sequence,
- self.input_sequences[1].sequence,
+ shorter_seq.sequence,
+ longer_seq.sequence,
],
**kwargs,
- ).align()
+ )
+ alignment_result = pairwise_aligner.align()
+ self.method = pairwise_aligner.mode
+
+ # elif len(self.input_sequences) > 2:
+ # # run multi pairwise alignment
+ # pairs = list(combinations(protien_infos, 2))
+
+ # if n_jobs is None:
+ # n_jobs = cpu_count()
+
+ # alignments = Parallel(n_jobs=n_jobs, prefer="processes")(
+ # delayed(pairwise_alignment)(
+ # reference,
+ # query,
+ # mode,
+ # match,
+ # mismatch,
+ # gap_open,
+ # gap_extend,
+ # substitution_matrix,
+ # )
+ # for reference, query in tqdm(pairs, desc="⛓️ Aligning sequences")
+ # )
+
+ # return alignments
+
+ else:
+ raise ValueError(
+ f"Alignment Error. Recieved {len(self.input_sequences)} sequences. Expected 2."
+ )
+
+ return self._map_pairwise_alignment_results(alignment_result)
+
+ def _map_pairwise_alignment_results(self, alignment_result: BioAlignment):
+ from pyeed.core.pairwisealignment import PairwiseAlignment
+
+ shorter_seq, longer_seq = sorted(
+ self.input_sequences, key=lambda x: len(x.sequence)
+ )
+
+ self.aligned_sequences = [
+ Sequence(
+ source_id=shorter_seq.source_id,
+ sequence=alignment_result[0],
+ ),
+ Sequence(
+ source_id=longer_seq.source_id,
+ sequence=alignment_result[1],
+ ),
+ ]
+
+ identities = alignment_result.counts().identities
+ identity = identities / len(shorter_seq.sequence)
+
+ pairwise_alignment = PairwiseAlignment(
+ input_sequences=self.input_sequences,
+ method=self.method,
+ aligned_sequences=self.aligned_sequences,
+ score=alignment_result.score,
+ gaps=alignment_result.counts().gaps,
+ identity=identity,
+ mismatches=alignment_result.counts().mismatches,
+ )
- # self.aligned_sequences = [
- # Sequence(source_id=seq.id, sequence=str(seq.seq))
- # for seq in alignment_reuslt
- # ]
+ pairwise_alignment.apply_standard_numbering()
- # TODO: Alignment has no ID attriburte
- # TODO: Map to data model
- return alignment_reuslt
+ return pairwise_alignment
@classmethod
def from_sequences(
@@ -198,7 +264,7 @@ def from_sequences(
)
if aligner is not None:
- alignment.align(aligner, **kwargs)
+ return alignment.align(aligner, **kwargs)
return alignment
From 50f1fb73e34ba732eb8df2bdc469a5d15d1e03f8 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Tue, 20 Feb 2024 17:23:20 +0100
Subject: [PATCH 03/13] refactored pairwise alignment
---
examples/test.ipynb | 112 ++++++++++++++++++++++++++++++++++----------
1 file changed, 87 insertions(+), 25 deletions(-)
diff --git a/examples/test.ipynb b/examples/test.ipynb
index fddfea96..9fbf2b89 100644
--- a/examples/test.ipynb
+++ b/examples/test.ipynb
@@ -9,7 +9,7 @@
},
{
"cell_type": "code",
- "execution_count": 1,
+ "execution_count": 2,
"metadata": {},
"outputs": [],
"source": [
@@ -17,7 +17,8 @@
"%autoreload 2\n",
"from pyeed.core import ProteinInfo\n",
"from pyeed.core import Alignment\n",
- "from pyeed.aligners import ClustalOmega\n"
+ "from pyeed.aligners import ClustalOmega\n",
+ "from pyeed.aligners import PairwiseAligner"
]
},
{
@@ -111,14 +112,18 @@
},
{
"cell_type": "code",
- "execution_count": null,
+ "execution_count": 3,
"metadata": {},
"outputs": [
{
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🏃 Running CLUSTALO\n"
+ "ename": "NameError",
+ "evalue": "name 'blast_results' is not defined",
+ "output_type": "error",
+ "traceback": [
+ "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
+ "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
+ "Cell \u001b[0;32mIn[3], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m alignment \u001b[38;5;241m=\u001b[39m Alignment\u001b[38;5;241m.\u001b[39mfrom_sequences(\u001b[43mblast_results\u001b[49m)\n\u001b[1;32m 2\u001b[0m alignment\u001b[38;5;241m.\u001b[39malign(ClustalOmega)\n",
+ "\u001b[0;31mNameError\u001b[0m: name 'blast_results' is not defined"
]
}
],
@@ -161,18 +166,25 @@
"execution_count": 1,
"metadata": {},
"outputs": [],
- "source": []
+ "source": [
+ "%reload_ext autoreload\n",
+ "%autoreload 2\n",
+ "from pyeed.core import ProteinInfo\n",
+ "from pyeed.core import Alignment\n",
+ "from pyeed.aligners import ClustalOmega\n",
+ "from pyeed.aligners import PairwiseAligner"
+ ]
},
{
"cell_type": "code",
- "execution_count": 1,
+ "execution_count": 2,
"metadata": {},
"outputs": [
{
"name": "stderr",
"output_type": "stream",
"text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 1292.84it/s]\n"
+ "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 44.96it/s]\n"
]
},
{
@@ -184,9 +196,6 @@
}
],
"source": [
- "from pyeed.core import ProteinInfo, Alignment\n",
- "from pyeed.aligners import ClustalOmega\n",
- "\n",
"# Get sequences\n",
"ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\", \"AAT46414.1\", \"AAT46415.1\"]\n",
"sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
@@ -197,37 +206,90 @@
},
{
"cell_type": "code",
- "execution_count": 2,
+ "execution_count": 1,
+ "metadata": {},
+ "outputs": [
+ {
+ "ename": "NameError",
+ "evalue": "name 'alignment' is not defined",
+ "output_type": "error",
+ "traceback": [
+ "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
+ "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
+ "Cell \u001b[0;32mIn[1], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m \u001b[38;5;28mprint\u001b[39m(\u001b[43malignment\u001b[49m)\n",
+ "\u001b[0;31mNameError\u001b[0m: name 'alignment' is not defined"
+ ]
+ }
+ ],
+ "source": [
+ "print(alignment)"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 9,
"metadata": {},
"outputs": [
{
"name": "stderr",
"output_type": "stream",
"text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 2/2 [00:00<00:00, 558.68it/s]"
+ "⬇️ Fetching protein sequences: 100%|██████████| 2/2 [00:00<00:00, 1000.55it/s]\n"
]
- },
+ }
+ ],
+ "source": [
+ "from pyeed.core import ProteinInfo, Alignment\n",
+ "from pyeed.aligners import PairwiseAligner\n",
+ "\n",
+ "# Get sequences\n",
+ "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\"]\n",
+ "sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
+ "\n",
+ "# Create and run alignment\n",
+ "alignment = Alignment.from_sequences(\n",
+ " sequences, aligner=PairwiseAligner, mode=\"local\")"
+ ]
+ },
+ {
+ "cell_type": "markdown",
+ "metadata": {},
+ "source": [
+ "## Multi Pairwise Alignment"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 11,
+ "metadata": {},
+ "outputs": [
{
- "name": "stdout",
+ "name": "stderr",
"output_type": "stream",
"text": [
- "[Sequence(id='sequence8', source_id='QGC48744.1', sequence='ALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW'), Sequence(id='sequence9', source_id='AAT46413.1', sequence='MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMLSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW')]\n"
+ "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 38.26it/s]\n"
]
},
{
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "\n"
+ "ename": "UnboundLocalError",
+ "evalue": "local variable 'alignment_result' referenced before assignment",
+ "output_type": "error",
+ "traceback": [
+ "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
+ "\u001b[0;31mUnboundLocalError\u001b[0m Traceback (most recent call last)",
+ "Cell \u001b[0;32mIn[11], line 8\u001b[0m\n\u001b[1;32m 5\u001b[0m sequences \u001b[38;5;241m=\u001b[39m ProteinInfo\u001b[38;5;241m.\u001b[39mfrom_ncbi(ncbi_accessions)\n\u001b[1;32m 7\u001b[0m \u001b[38;5;66;03m# Create and run alignment\u001b[39;00m\n\u001b[0;32m----> 8\u001b[0m alignment \u001b[38;5;241m=\u001b[39m \u001b[43mAlignment\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mfrom_sequences\u001b[49m\u001b[43m(\u001b[49m\u001b[43msequences\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43maligner\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mPairwiseAligner\u001b[49m\u001b[43m)\u001b[49m\n",
+ "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:247\u001b[0m, in \u001b[0;36mAlignment.from_sequences\u001b[0;34m(cls, sequences, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 242\u001b[0m alignment \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mcls\u001b[39m(\n\u001b[1;32m 243\u001b[0m input_sequences\u001b[38;5;241m=\u001b[39msequences,\n\u001b[1;32m 244\u001b[0m )\n\u001b[1;32m 246\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m aligner \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m:\n\u001b[0;32m--> 247\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43malignment\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43malign\u001b[49m\u001b[43m(\u001b[49m\u001b[43maligner\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 249\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m alignment\n",
+ "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:144\u001b[0m, in \u001b[0;36mAlignment.align\u001b[0;34m(self, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 141\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_container_align(aligner, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs)\n\u001b[1;32m 143\u001b[0m \u001b[38;5;28;01melif\u001b[39;00m \u001b[38;5;28missubclass\u001b[39m(aligner, PairwiseAligner):\n\u001b[0;32m--> 144\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_python_align\u001b[49m\u001b[43m(\u001b[49m\u001b[43maligner\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 146\u001b[0m \u001b[38;5;28;01melse\u001b[39;00m:\n\u001b[1;32m 147\u001b[0m \u001b[38;5;28;01mraise\u001b[39;00m \u001b[38;5;167;01mValueError\u001b[39;00m(\n\u001b[1;32m 148\u001b[0m \u001b[38;5;124m\"\u001b[39m\u001b[38;5;124maligner must be an instance of AbstractContainer or PairwiseAligner\u001b[39m\u001b[38;5;124m\"\u001b[39m\n\u001b[1;32m 149\u001b[0m )\n",
+ "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:191\u001b[0m, in \u001b[0;36mAlignment._python_align\u001b[0;34m(self, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 188\u001b[0m alignment_result \u001b[38;5;241m=\u001b[39m pairwise_aligner\u001b[38;5;241m.\u001b[39malign()\n\u001b[1;32m 189\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mmethod \u001b[38;5;241m=\u001b[39m pairwise_aligner\u001b[38;5;241m.\u001b[39mmode\n\u001b[0;32m--> 191\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_map_pairwise_alignment_results(\u001b[43malignment_result\u001b[49m)\n",
+ "\u001b[0;31mUnboundLocalError\u001b[0m: local variable 'alignment_result' referenced before assignment"
]
}
],
"source": [
- "from pyeed.core import ProteinInfo, Alignment\n",
"from pyeed.aligners import PairwiseAligner\n",
"\n",
- "# Get sequences\n",
- "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\"]\n",
+ "\n",
+ "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\", \"AAT46414.1\", \"AAT46415.1\"]\n",
"sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
"\n",
"# Create and run alignment\n",
From c04a8665a9f1050240ca2811ec5cb768e4e43861 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Thu, 22 Feb 2024 10:20:59 +0100
Subject: [PATCH 04/13] added docstrings, refactored alinger integration
---
pyeed/core/alignment.py | 221 +++++++++++++++++++++++++++++-----------
1 file changed, 163 insertions(+), 58 deletions(-)
diff --git a/pyeed/core/alignment.py b/pyeed/core/alignment.py
index 6135bffb..066d469f 100644
--- a/pyeed/core/alignment.py
+++ b/pyeed/core/alignment.py
@@ -1,24 +1,62 @@
+from numpy import short
import sdRDM
from tqdm import tqdm
from itertools import combinations
-from typing import List, Optional, Union
+from typing import List, Optional, Union, Tuple, TYPE_CHECKING
from pydantic import Field, validator
from sdRDM.base.listplus import ListPlus
from sdRDM.base.utils import forge_signature, IDGenerator
from Bio.Align import Alignment as BioAlignment
+from joblib import Parallel, delayed, cpu_count
-from pyeed.aligners.pairwise import PairwiseAligner
+from pyeed.core.pairwisealignment import PairwiseAlignment
-from .abstractsequence import AbstractSequence
-from .sequence import Sequence
-from .standardnumbering import StandardNumbering
+if TYPE_CHECKING:
+ from pyeed.core.dnainfo import DNAInfo
+ from pyeed.core.proteininfo import ProteinInfo
+ from .abstractsequence import AbstractSequence
+ from pyeed.containers.abstract_container import AbstractContainer
+ from pyeed.aligners.pairwise import PairwiseAligner
-from pyeed.containers.abstract_container import AbstractContainer
+
+from .standardnumbering import StandardNumbering
+from .sequence import Sequence
+from .abstractsequence import AbstractSequence
@forge_signature
class Alignment(sdRDM.DataModel):
- """"""
+ """
+ Description of the Alignment class.
+
+ Attributes:
+ id (Optional[str]): Unique identifier of the given object.
+ method (Optional[str]): Applied alignment method.
+ consensus (Optional[str]): Consensus sequence of the alignment.
+ input_sequences (List[Sequence]): Sequences of the alignment.
+ aligned_sequences (List[Sequence]): Aligned sequences of the alignment.
+ standard_numberings (List[StandardNumbering]): Standard numbering of the aligned sequences.
+
+ Methods:
+ add_to_input_sequences(source_id: Optional[str] = None, sequence: Optional[str] = None, id: Optional[str] = None) -> None:
+ Adds an object of type 'Sequence' to attribute input_sequences.
+
+ add_to_aligned_sequences(source_id: Optional[str] = None, sequence: Optional[str] = None, id: Optional[str] = None) -> None:
+ Adds an object of type 'Sequence' to attribute aligned_sequences.
+
+ add_to_standard_numberings(reference_id: Optional[str] = None, numbered_id: Optional[str] = None, numbering: List[str] = ListPlus(), id: Optional[str] = None) -> None:
+ Adds an object of type 'StandardNumbering' to attribute standard_numberings.
+
+ align(aligner: Union["AbstractContainer", "PairwiseAligner"], **kwargs):
+ Aligns the input sequences using the specified aligner.
+
+ apply_standard_numbering(reference: Sequence = None):
+ Applies standard numbering to the aligned sequences.
+
+ from_sequences(sequences: List[Union["ProteinInfo", "DNAInfo"]], aligner: Union["AbstractContainer", "PairwiseAligner"] = None, **kwargs):
+ Creates an Alignment object from a list of sequences and optionally aligns them.
+
+ """
id: Optional[str] = Field(
description="Unique identifier of the given object.",
@@ -134,7 +172,25 @@ def add_to_standard_numberings(
self.standard_numberings.append(StandardNumbering(**params))
return self.standard_numberings[-1]
- def align(self, aligner: Union[AbstractContainer, PairwiseAligner], **kwargs):
+ def align(self, aligner: Union["AbstractContainer", "PairwiseAligner"], **kwargs):
+ """
+ Aligns the input sequences using the specified aligner.
+
+ Args:
+ aligner (Union[AbstractContainer, PairwiseAligner]): The aligner object to use for alignment.
+ **kwargs: Additional keyword arguments to pass to the aligner.
+
+ Returns:
+ Alignment or List[PairwiseAlignment]: The aligned sequences. If a Multi sequence aligner is used, an Alignment object will be returned.
+ If a PairwiseAligner is used, a list of PairwiseAlignment object will be returned. If more than two sequences are provided,
+ a list of PairwiseAlignment objects will be returned.
+
+ Raises:
+ ValueError: If the aligner is not an instance of AbstractContainer or PairwiseAligner.
+ """
+
+ from pyeed.containers.abstract_container import AbstractContainer
+ from pyeed.aligners.pairwise import PairwiseAligner
if issubclass(aligner, AbstractContainer):
return self._container_align(aligner, **kwargs)
@@ -147,7 +203,15 @@ def align(self, aligner: Union[AbstractContainer, PairwiseAligner], **kwargs):
"aligner must be an instance of AbstractContainer or PairwiseAligner"
)
- def _container_align(self, aligner: AbstractContainer, **kwargs):
+ def _container_align(self, aligner: "AbstractContainer", **kwargs):
+ """Runs alignment using a containerized aligner.
+
+ Args:
+ aligner (AbstractContainer): Containerized aligner to be called.
+
+ Returns:
+ Any: Alignment result
+ """
sequences = [seq.fasta_string() for seq in self.input_sequences]
alignment = aligner().align(sequences=sequences)
@@ -170,77 +234,106 @@ def _container_align(self, aligner: AbstractContainer, **kwargs):
return self
- def _python_align(self, aligner: PairwiseAligner, **kwargs):
+ def _map_to_pairwisealignment(self):
+
+ from pyeed.core.pairwisealignment import PairwiseAlignment
+
+ return PairwiseAlignment(
+ input_sequences=self.input_sequences,
+ method=self.method,
+ aligned_sequences=self.aligned_sequences,
+ standard_numberings=self.standard_numberings,
+ )
+
+ def _python_align(self, aligner: "PairwiseAligner", **kwargs):
+ """Runs alignment using a python-based aligner.
+ Args:
+ aligner (PairwiseAligner): Python-based aligner to be called.
+
+ Raises:
+ ValueError: If the number of sequences is less than 2.
+
+ Returns:
+ _type_: Alignment result
+ """
+
+ # Pairwise alignment
if len(self.input_sequences) == 2:
- shorter_seq, longer_seq = sorted(
- self.input_sequences, key=lambda x: len(x.sequence)
- )
pairwise_aligner = aligner(
sequences=[
- shorter_seq.sequence,
- longer_seq.sequence,
+ self.input_sequences[0].sequence,
+ self.input_sequences[1].sequence,
],
**kwargs,
)
alignment_result = pairwise_aligner.align()
self.method = pairwise_aligner.mode
- # elif len(self.input_sequences) > 2:
- # # run multi pairwise alignment
- # pairs = list(combinations(protien_infos, 2))
-
- # if n_jobs is None:
- # n_jobs = cpu_count()
-
- # alignments = Parallel(n_jobs=n_jobs, prefer="processes")(
- # delayed(pairwise_alignment)(
- # reference,
- # query,
- # mode,
- # match,
- # mismatch,
- # gap_open,
- # gap_extend,
- # substitution_matrix,
- # )
- # for reference, query in tqdm(pairs, desc="⛓️ Aligning sequences")
- # )
-
- # return alignments
+ return self._map_pairwise_alignment_results(
+ alignment_result,
+ pair=(
+ self.input_sequences[0],
+ self.input_sequences[1],
+ ),
+ mode=pairwise_aligner.mode,
+ )
+
+ # Multi pairwise alignment
+ elif len(self.input_sequences) > 2:
+ pairs = list(combinations(self.input_sequences, 2))
+
+ aligners = [
+ aligner(sequences=[s.sequence for s in pair], **kwargs)
+ for pair in pairs
+ ]
+
+ alignments = Parallel(n_jobs=cpu_count(), prefer="processes")(
+ delayed(a.align)()
+ for a in tqdm(aligners, desc="⛓️ Running pairwise alignments")
+ )
+
+ return [
+ self._map_pairwise_alignment_results(
+ alignment, pair, mode=aligners[0].mode
+ )
+ for alignment, pair in zip(alignments, pairs)
+ ]
else:
raise ValueError(
f"Alignment Error. Recieved {len(self.input_sequences)} sequences. Expected 2."
)
- return self._map_pairwise_alignment_results(alignment_result)
+ def _map_pairwise_alignment_results(
+ self, alignment_result: BioAlignment, pair: Tuple[Sequence, Sequence], mode: str
+ ) -> PairwiseAlignment:
+ """Maps the results of a pairwise alignment to a PairwiseAlignment object.
- def _map_pairwise_alignment_results(self, alignment_result: BioAlignment):
- from pyeed.core.pairwisealignment import PairwiseAlignment
+ Args:
+ alignment_result (BioAlignment): The result of the pairwise alignment.
+ pair (Tuple[Sequence, Sequence]): The pair of sequences that were aligned.
+ mode (str): The alignment mode used.
- shorter_seq, longer_seq = sorted(
- self.input_sequences, key=lambda x: len(x.sequence)
- )
+ Returns:
+ PairwiseAlignment: PairwiseAlignment object
+ """
+ from pyeed.core.pairwisealignment import PairwiseAlignment
self.aligned_sequences = [
- Sequence(
- source_id=shorter_seq.source_id,
- sequence=alignment_result[0],
- ),
- Sequence(
- source_id=longer_seq.source_id,
- sequence=alignment_result[1],
- ),
+ Sequence(source_id=pair[0].source_id, sequence=alignment_result[0]),
+ Sequence(source_id=pair[1].source_id, sequence=alignment_result[1]),
]
+ shorter_seq = min(self.input_sequences, key=lambda x: len(x.sequence))
+
identities = alignment_result.counts().identities
identity = identities / len(shorter_seq.sequence)
pairwise_alignment = PairwiseAlignment(
- input_sequences=self.input_sequences,
- method=self.method,
+ input_sequences=list(pair),
+ method=mode,
aligned_sequences=self.aligned_sequences,
score=alignment_result.score,
gaps=alignment_result.counts().gaps,
@@ -248,17 +341,30 @@ def _map_pairwise_alignment_results(self, alignment_result: BioAlignment):
mismatches=alignment_result.counts().mismatches,
)
- pairwise_alignment.apply_standard_numbering()
-
return pairwise_alignment
@classmethod
def from_sequences(
cls,
- sequences: List[AbstractSequence],
- aligner: Union[AbstractContainer, PairwiseAligner] = None,
+ sequences: List[Union["ProteinInfo", "DNAInfo"]],
+ aligner: Union["AbstractContainer", "PairwiseAligner"] = None,
**kwargs,
):
+ """
+ Creates an instance of the Alignment class from a list of sequences.
+ If an aligner is provided, it also aligns the sequences.
+
+ Args:
+ sequences (List[Union["ProteinInfo", "DNAInfo"]]): A list of sequences to be aligned.
+ aligner (Union["AbstractContainer", "PairwiseAligner"], optional): The aligner object to use for alignment.
+ If not provided, the sequences will not be aligned.
+ **kwargs: Additional keyword arguments to pass to the aligner.
+
+ Returns:
+ Alignment: An instance of the Alignment class with the provided sequences.
+ If an aligner was provided, the sequences will be aligned.
+ """
+
alignment = cls(
input_sequences=sequences,
)
@@ -279,7 +385,6 @@ def _get_numbering_string(reference: str, query: str) -> List[str]:
Returns:
List[str]: A list of pairwise numbering.
-
"""
numbering = []
From efcc4609a8550a70d24660ee1ca2e395ff2546c9 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Thu, 22 Feb 2024 10:47:06 +0100
Subject: [PATCH 05/13] added threads to os.cpu_count()
---
pyeed/aligners/clustalo.py | 3 ++-
1 file changed, 2 insertions(+), 1 deletion(-)
diff --git a/pyeed/aligners/clustalo.py b/pyeed/aligners/clustalo.py
index 2a944898..8b82e1b4 100644
--- a/pyeed/aligners/clustalo.py
+++ b/pyeed/aligners/clustalo.py
@@ -48,7 +48,8 @@ def setup_command(self):
Returns:
str: The command to run the ClustalOmega container.
"""
- return "clustalo -i /data/input.fasta -o /data/output.clu --outfmt=clu"
+ threads = os.cpu_count()
+ return f"clustalo -i /data/input.fasta -o /data/output.clu --outfmt=clu --threads={threads}"
def extract_output_data(self) -> MultipleSeqAlignment:
"""
From ac693124472d35679bd057c55a3b92904271c6f7 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Thu, 22 Feb 2024 10:47:27 +0100
Subject: [PATCH 06/13] refactored alignment
---
pyeed/aligners/abstract_aligner.py | 2 +-
pyeed/aligners/pairwise.py | 50 ++++++++------------------
pyeed/containers/abstract_container.py | 3 --
pyeed/core/alignment.py | 4 +--
4 files changed, 17 insertions(+), 42 deletions(-)
diff --git a/pyeed/aligners/abstract_aligner.py b/pyeed/aligners/abstract_aligner.py
index 0254da8f..17a65837 100644
--- a/pyeed/aligners/abstract_aligner.py
+++ b/pyeed/aligners/abstract_aligner.py
@@ -1,6 +1,6 @@
from typing import List
from abc import ABC, abstractmethod
-from pydantic import BaseModel, Field, PrivateAttr
+from pydantic import BaseModel, Field
class AbstractAligner(BaseModel, ABC):
diff --git a/pyeed/aligners/pairwise.py b/pyeed/aligners/pairwise.py
index c5852066..a66adcb0 100644
--- a/pyeed/aligners/pairwise.py
+++ b/pyeed/aligners/pairwise.py
@@ -1,13 +1,14 @@
-from pydantic import BaseModel, Field, validator
-import sdRDM
-from typing import Any, List, Optional
-from itertools import combinations
-from Bio.Align import PairwiseAligner as BioPairwiseAligner
-from tqdm import tqdm
+from pydantic import Field, validator
+from typing import TYPE_CHECKING, Any
+
from pyeed.aligners import AbstractAligner
+from Bio.Align import PairwiseAligner as BioPairwiseAligner
+if TYPE_CHECKING:
+ from Bio.Align import Alignment as BioAlignment
+ from Bio.Align.substitution_matrices import Array as BioSubstitutionMatrix
-from joblib import Parallel, delayed, cpu_count
+from pyeed.core.sequence import Sequence
class PairwiseAligner(AbstractAligner):
@@ -60,7 +61,7 @@ def substitution_matrix_validator(cls, substitution_matrix):
return substitution_matrix
- def align(self):
+ def align(self) -> "BioAlignment":
"""
Aligns two sequences using the specified alignment parameters of the `PairwiseAligner` class.
@@ -83,37 +84,16 @@ def align(self):
if self.substitution_matrix != "None":
aligner.substitution_matrix = self._load_substitution_matrix()
- shorter_seq, longer_seq = sorted(self.sequences, key=lambda x: len(x))
-
- alignment_result = aligner.align(shorter_seq, longer_seq)[0]
+ alignment_result = aligner.align(self.sequences[0], self.sequences[1])[0]
return alignment_result
- def _load_substitution_matrix(self) -> Any:
+ def _load_substitution_matrix(self) -> "BioSubstitutionMatrix":
from Bio.Align import substitution_matrices
return substitution_matrices.load(self.substitution_matrix)
- # def align_multi_pairwise(self):
- # n_jobs = cpu_count()
-
- # pairs = list(combinations(protien_infos, 2))
-
- # if n_jobs is None:
- # n_jobs = cpu_count()
-
- # alignments = Parallel(n_jobs=n_jobs, prefer="processes")(
- # delayed(pairwise_alignment)(
- # reference,
- # query,
- # mode,
- # match,
- # mismatch,
- # gap_open,
- # gap_extend,
- # substitution_matrix,
- # )
- # for reference, query in tqdm(pairs, desc="⛓️ Aligning sequences")
- # )
-
- # return alignments
+
+if __name__ == "__main__":
+
+ seq1 = Sequence(sequence="wee")
diff --git a/pyeed/containers/abstract_container.py b/pyeed/containers/abstract_container.py
index aa8094a7..1e0795e0 100644
--- a/pyeed/containers/abstract_container.py
+++ b/pyeed/containers/abstract_container.py
@@ -13,9 +13,6 @@
from docker.errors import DockerException
-from pyeed.ncbi import seq_io
-
-
class ToolImage(Enum):
CLUSTALO = "biocontainers/clustal-omega:v1.2.1_cv5"
BLAST = "haeussma/blast:latest"
diff --git a/pyeed/core/alignment.py b/pyeed/core/alignment.py
index 066d469f..99bb4a7f 100644
--- a/pyeed/core/alignment.py
+++ b/pyeed/core/alignment.py
@@ -9,8 +9,6 @@
from Bio.Align import Alignment as BioAlignment
from joblib import Parallel, delayed, cpu_count
-from pyeed.core.pairwisealignment import PairwiseAlignment
-
if TYPE_CHECKING:
from pyeed.core.dnainfo import DNAInfo
from pyeed.core.proteininfo import ProteinInfo
@@ -308,7 +306,7 @@ def _python_align(self, aligner: "PairwiseAligner", **kwargs):
def _map_pairwise_alignment_results(
self, alignment_result: BioAlignment, pair: Tuple[Sequence, Sequence], mode: str
- ) -> PairwiseAlignment:
+ ) -> "PairwiseAlignment":
"""Maps the results of a pairwise alignment to a PairwiseAlignment object.
Args:
From 808eb879241142812caca4f87ca00d4875a08923 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Thu, 22 Feb 2024 10:47:48 +0100
Subject: [PATCH 07/13] modified imports
---
pyeed/core/dnainfo.py | 3 ++-
pyeed/core/proteininfo.py | 9 +++++++--
pyeed/ncbi/seq_io.py | 3 ---
pyeed/network/__init__.py | 1 -
4 files changed, 9 insertions(+), 7 deletions(-)
diff --git a/pyeed/core/dnainfo.py b/pyeed/core/dnainfo.py
index 089f770b..b6d34065 100644
--- a/pyeed/core/dnainfo.py
+++ b/pyeed/core/dnainfo.py
@@ -7,7 +7,6 @@
from .span import Span
from .dnaregiontype import DNARegionType
from .dnaregion import DNARegion
-from ..ncbi.seq_io import get_ncbi_entry, _seqio_to_dna_info
@forge_signature
@@ -63,6 +62,8 @@ def add_to_regions(
@classmethod
def from_ncbi(cls, accession_id: str) -> "DNAInfo":
+ from pyeed.ncbi.seq_io import get_ncbi_entry, _seqio_to_dna_info
+
seq_record = get_ncbi_entry(accession_id=accession_id, database="nucleotide")
return _seqio_to_dna_info(cls, seq_record)
diff --git a/pyeed/core/proteininfo.py b/pyeed/core/proteininfo.py
index d367b39f..4173892d 100644
--- a/pyeed/core/proteininfo.py
+++ b/pyeed/core/proteininfo.py
@@ -14,8 +14,6 @@
from .substrate import Substrate
from .dnaregion import DNARegion
from .proteinsitetype import ProteinSiteType
-from ..ncbi.seq_io import _seqio_to_nucleotide_info, get_ncbi_entry, get_ncbi_entrys
-
from pyeed.containers.abstract_container import Blastp
@@ -162,6 +160,8 @@ def add_to_substrates(
@classmethod
def from_ncbi(cls, accession_id: str) -> "ProteinInfo":
+ from ..ncbi.seq_io import _seqio_to_nucleotide_info, get_ncbi_entry
+
"""
This method creates a 'ProteinInfo' object from a given NCBI ID.
@@ -182,12 +182,16 @@ def from_ncbi(cls, accession_id: str) -> "ProteinInfo":
@classmethod
def _from_seq_record(cls, seq_record) -> "ProteinInfo":
+ from ..ncbi.seq_io import _seqio_to_nucleotide_info
+
return _seqio_to_nucleotide_info(cls, seq_record)
@classmethod
def from_accessions(
cls, accession_ids: List[str], email: str = None, api_key: str = None
) -> List["ProteinInfo"]:
+ from ..ncbi.seq_io import get_ncbi_entrys
+
seq_entries = get_ncbi_entrys(
accession_ids=accession_ids,
database="protein",
@@ -216,6 +220,7 @@ def ncbi_blastp(
Returns:
List[ProteinInfo]: List of 'ProteinInfo' objects that are the result of the blast search.
"""
+ from ..ncbi.seq_io import get_ncbi_entrys
print(f"🏃🏼♀️ Running PBLAST")
print(f"╭── protein name: {self.name}")
diff --git a/pyeed/ncbi/seq_io.py b/pyeed/ncbi/seq_io.py
index a8ee324f..5a869431 100644
--- a/pyeed/ncbi/seq_io.py
+++ b/pyeed/ncbi/seq_io.py
@@ -1,14 +1,11 @@
import re
import secrets
-from datetime import datetime
from tqdm import tqdm
from typing import List
from Bio import SeqIO, Entrez
-from pyeed.core.citation import Citation
from pyeed.core.dnaregion import DNARegion
from pyeed.core.dnaregiontype import DNARegionType
from pyeed.core.proteinregion import ProteinRegion
-from pyeed.core.proteinregiontype import ProteinRegionType
from pyeed.core.proteinsitetype import ProteinSiteType
from pyeed.core.site import Site
diff --git a/pyeed/network/__init__.py b/pyeed/network/__init__.py
index 7343b301..e69de29b 100644
--- a/pyeed/network/__init__.py
+++ b/pyeed/network/__init__.py
@@ -1 +0,0 @@
-from .network import pairwise_network
From 02206654d83335586d4a316f6b9f7b76757bc8de Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Thu, 22 Feb 2024 10:47:57 +0100
Subject: [PATCH 08/13] tested alignments and networks
---
examples/test.ipynb | 274 +++++++++++++-------------
pyeed/network/network.py | 404 +++++++++++++++++++++------------------
2 files changed, 361 insertions(+), 317 deletions(-)
diff --git a/examples/test.ipynb b/examples/test.ipynb
index 9fbf2b89..dab953cc 100644
--- a/examples/test.ipynb
+++ b/examples/test.ipynb
@@ -4,12 +4,12 @@
"cell_type": "markdown",
"metadata": {},
"source": [
- "# Test Docker-integrated Aligners"
+ "# Test Aligners"
]
},
{
"cell_type": "code",
- "execution_count": 2,
+ "execution_count": 1,
"metadata": {},
"outputs": [],
"source": [
@@ -17,8 +17,7 @@
"%autoreload 2\n",
"from pyeed.core import ProteinInfo\n",
"from pyeed.core import Alignment\n",
- "from pyeed.aligners import ClustalOmega\n",
- "from pyeed.aligners import PairwiseAligner"
+ "from pyeed.aligners import ClustalOmega"
]
},
{
@@ -37,35 +36,17 @@
"metadata": {},
"outputs": [
{
- "ename": "KeyboardInterrupt",
- "evalue": "",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mKeyboardInterrupt\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[3], line 2\u001b[0m\n\u001b[1;32m 1\u001b[0m \u001b[38;5;66;03m# Run local blastp search\u001b[39;00m\n\u001b[0;32m----> 2\u001b[0m blast_results \u001b[38;5;241m=\u001b[39m \u001b[43mald1\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mblastp\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m 3\u001b[0m \u001b[43m \u001b[49m\u001b[43mdb_path\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;124;43m\"\u001b[39;49m\u001b[38;5;124;43m/Users/max/Documents/GitHub/blast-db/data/source\u001b[39;49m\u001b[38;5;124;43m\"\u001b[39;49m\u001b[43m,\u001b[49m\n\u001b[1;32m 4\u001b[0m \u001b[43m \u001b[49m\u001b[43mn_hits\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;241;43m100\u001b[39;49m\u001b[43m,\u001b[49m\n\u001b[1;32m 5\u001b[0m \u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/proteininfo.py:261\u001b[0m, in \u001b[0;36mProteinInfo.blastp\u001b[0;34m(self, db_path, identity, evalue, n_hits, subst_matrix, word_size, gapopen, gapextend, threshold, n_cores, ncbi_key)\u001b[0m\n\u001b[1;32m 247\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21mblastp\u001b[39m(\n\u001b[1;32m 248\u001b[0m \u001b[38;5;28mself\u001b[39m,\n\u001b[1;32m 249\u001b[0m db_path: \u001b[38;5;28mstr\u001b[39m,\n\u001b[0;32m (...)\u001b[0m\n\u001b[1;32m 259\u001b[0m ncbi_key: \u001b[38;5;28mstr\u001b[39m \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;01mNone\u001b[39;00m,\n\u001b[1;32m 260\u001b[0m ):\n\u001b[0;32m--> 261\u001b[0m blaster \u001b[38;5;241m=\u001b[39m \u001b[43mBlastp\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m 262\u001b[0m \u001b[43m \u001b[49m\u001b[43m_db_path\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mdb_path\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 263\u001b[0m \u001b[43m \u001b[49m\u001b[43midentity\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43midentity\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 264\u001b[0m \u001b[43m \u001b[49m\u001b[43mevalue\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mevalue\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 265\u001b[0m \u001b[43m \u001b[49m\u001b[43mn_hits\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mn_hits\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 266\u001b[0m \u001b[43m \u001b[49m\u001b[43msubst_matrix\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43msubst_matrix\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 267\u001b[0m \u001b[43m \u001b[49m\u001b[43mword_size\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mword_size\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 268\u001b[0m \u001b[43m \u001b[49m\u001b[43mgapopen\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mgapopen\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 269\u001b[0m \u001b[43m \u001b[49m\u001b[43mgapextend\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mgapextend\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 270\u001b[0m \u001b[43m \u001b[49m\u001b[43mthreshold\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mthreshold\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 271\u001b[0m \u001b[43m \u001b[49m\u001b[43mn_cores\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mn_cores\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 272\u001b[0m \u001b[43m \u001b[49m\u001b[43mncbi_key\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mncbi_key\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 273\u001b[0m \u001b[43m \u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 275\u001b[0m command \u001b[38;5;241m=\u001b[39m blaster\u001b[38;5;241m.\u001b[39msetup_command()\n\u001b[1;32m 276\u001b[0m accession_ids \u001b[38;5;241m=\u001b[39m blaster\u001b[38;5;241m.\u001b[39mrun_container(command\u001b[38;5;241m=\u001b[39mcommand, data\u001b[38;5;241m=\u001b[39m\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mto_fasta())\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/containers/abstract_container.py:152\u001b[0m, in \u001b[0;36mBlastp.__init__\u001b[0;34m(self, _db_path, ncbi_key, **kwargs)\u001b[0m\n\u001b[1;32m 151\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21m__init__\u001b[39m(\u001b[38;5;28mself\u001b[39m, _db_path: \u001b[38;5;28mstr\u001b[39m, ncbi_key: \u001b[38;5;28mstr\u001b[39m \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;01mNone\u001b[39;00m, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs):\n\u001b[0;32m--> 152\u001b[0m \u001b[38;5;28;43msuper\u001b[39;49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[38;5;21;43m__init__\u001b[39;49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 153\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_db_path \u001b[38;5;241m=\u001b[39m _db_path\n\u001b[1;32m 154\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_ncbi_key:\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/containers/abstract_container.py:65\u001b[0m, in \u001b[0;36mAbstractContainer.__init__\u001b[0;34m(self, **kwargs)\u001b[0m\n\u001b[1;32m 63\u001b[0m \u001b[38;5;28msuper\u001b[39m()\u001b[38;5;241m.\u001b[39m\u001b[38;5;21m__init__\u001b[39m(\u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs)\n\u001b[1;32m 64\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_tempdir_path \u001b[38;5;241m=\u001b[39m tempfile\u001b[38;5;241m.\u001b[39mmkdtemp()\n\u001b[0;32m---> 65\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_client \u001b[38;5;241m=\u001b[39m \u001b[43mdocker\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mfrom_env\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/client.py:94\u001b[0m, in \u001b[0;36mDockerClient.from_env\u001b[0;34m(cls, **kwargs)\u001b[0m\n\u001b[1;32m 92\u001b[0m version \u001b[38;5;241m=\u001b[39m kwargs\u001b[38;5;241m.\u001b[39mpop(\u001b[38;5;124m'\u001b[39m\u001b[38;5;124mversion\u001b[39m\u001b[38;5;124m'\u001b[39m, \u001b[38;5;28;01mNone\u001b[39;00m)\n\u001b[1;32m 93\u001b[0m use_ssh_client \u001b[38;5;241m=\u001b[39m kwargs\u001b[38;5;241m.\u001b[39mpop(\u001b[38;5;124m'\u001b[39m\u001b[38;5;124muse_ssh_client\u001b[39m\u001b[38;5;124m'\u001b[39m, \u001b[38;5;28;01mFalse\u001b[39;00m)\n\u001b[0;32m---> 94\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mcls\u001b[39;49m\u001b[43m(\u001b[49m\n\u001b[1;32m 95\u001b[0m \u001b[43m \u001b[49m\u001b[43mtimeout\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mtimeout\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 96\u001b[0m \u001b[43m \u001b[49m\u001b[43mmax_pool_size\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mmax_pool_size\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 97\u001b[0m \u001b[43m \u001b[49m\u001b[43mversion\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mversion\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 98\u001b[0m \u001b[43m \u001b[49m\u001b[43muse_ssh_client\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43muse_ssh_client\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 99\u001b[0m \u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs_from_env\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 100\u001b[0m \u001b[43m\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/client.py:45\u001b[0m, in \u001b[0;36mDockerClient.__init__\u001b[0;34m(self, *args, **kwargs)\u001b[0m\n\u001b[1;32m 44\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21m__init__\u001b[39m(\u001b[38;5;28mself\u001b[39m, \u001b[38;5;241m*\u001b[39margs, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs):\n\u001b[0;32m---> 45\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mapi \u001b[38;5;241m=\u001b[39m \u001b[43mAPIClient\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43margs\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/api/client.py:197\u001b[0m, in \u001b[0;36mAPIClient.__init__\u001b[0;34m(self, base_url, version, timeout, tls, user_agent, num_pools, credstore_env, use_ssh_client, max_pool_size)\u001b[0m\n\u001b[1;32m 192\u001b[0m \u001b[38;5;66;03m# version detection needs to be after unix adapter mounting\u001b[39;00m\n\u001b[1;32m 193\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m version \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m \u001b[38;5;129;01mor\u001b[39;00m (\u001b[38;5;28misinstance\u001b[39m(\n\u001b[1;32m 194\u001b[0m version,\n\u001b[1;32m 195\u001b[0m \u001b[38;5;28mstr\u001b[39m\n\u001b[1;32m 196\u001b[0m ) \u001b[38;5;129;01mand\u001b[39;00m version\u001b[38;5;241m.\u001b[39mlower() \u001b[38;5;241m==\u001b[39m \u001b[38;5;124m'\u001b[39m\u001b[38;5;124mauto\u001b[39m\u001b[38;5;124m'\u001b[39m):\n\u001b[0;32m--> 197\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_version \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_retrieve_server_version\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 198\u001b[0m \u001b[38;5;28;01melse\u001b[39;00m:\n\u001b[1;32m 199\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_version \u001b[38;5;241m=\u001b[39m version\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/api/client.py:213\u001b[0m, in \u001b[0;36mAPIClient._retrieve_server_version\u001b[0;34m(self)\u001b[0m\n\u001b[1;32m 211\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21m_retrieve_server_version\u001b[39m(\u001b[38;5;28mself\u001b[39m):\n\u001b[1;32m 212\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[0;32m--> 213\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mversion\u001b[49m\u001b[43m(\u001b[49m\u001b[43mapi_version\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mFalse\u001b[39;49;00m\u001b[43m)\u001b[49m[\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mApiVersion\u001b[39m\u001b[38;5;124m\"\u001b[39m]\n\u001b[1;32m 214\u001b[0m \u001b[38;5;28;01mexcept\u001b[39;00m \u001b[38;5;167;01mKeyError\u001b[39;00m \u001b[38;5;28;01mas\u001b[39;00m ke:\n\u001b[1;32m 215\u001b[0m \u001b[38;5;28;01mraise\u001b[39;00m DockerException(\n\u001b[1;32m 216\u001b[0m \u001b[38;5;124m'\u001b[39m\u001b[38;5;124mInvalid response from docker daemon: key \u001b[39m\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mApiVersion\u001b[39m\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124m'\u001b[39m\n\u001b[1;32m 217\u001b[0m \u001b[38;5;124m'\u001b[39m\u001b[38;5;124m is missing.\u001b[39m\u001b[38;5;124m'\u001b[39m\n\u001b[1;32m 218\u001b[0m ) \u001b[38;5;28;01mfrom\u001b[39;00m \u001b[38;5;21;01mke\u001b[39;00m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/api/daemon.py:181\u001b[0m, in \u001b[0;36mDaemonApiMixin.version\u001b[0;34m(self, api_version)\u001b[0m\n\u001b[1;32m 169\u001b[0m \u001b[38;5;250m\u001b[39m\u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[1;32m 170\u001b[0m \u001b[38;5;124;03mReturns version information from the server. Similar to the ``docker\u001b[39;00m\n\u001b[1;32m 171\u001b[0m \u001b[38;5;124;03mversion`` command.\u001b[39;00m\n\u001b[0;32m (...)\u001b[0m\n\u001b[1;32m 178\u001b[0m \u001b[38;5;124;03m If the server returns an error.\u001b[39;00m\n\u001b[1;32m 179\u001b[0m \u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[1;32m 180\u001b[0m url \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_url(\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124m/version\u001b[39m\u001b[38;5;124m\"\u001b[39m, versioned_api\u001b[38;5;241m=\u001b[39mapi_version)\n\u001b[0;32m--> 181\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_result(\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_get\u001b[49m\u001b[43m(\u001b[49m\u001b[43murl\u001b[49m\u001b[43m)\u001b[49m, json\u001b[38;5;241m=\u001b[39m\u001b[38;5;28;01mTrue\u001b[39;00m)\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/utils/decorators.py:44\u001b[0m, in \u001b[0;36mupdate_headers..inner\u001b[0;34m(self, *args, **kwargs)\u001b[0m\n\u001b[1;32m 42\u001b[0m \u001b[38;5;28;01melse\u001b[39;00m:\n\u001b[1;32m 43\u001b[0m kwargs[\u001b[38;5;124m'\u001b[39m\u001b[38;5;124mheaders\u001b[39m\u001b[38;5;124m'\u001b[39m]\u001b[38;5;241m.\u001b[39mupdate(\u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_general_configs[\u001b[38;5;124m'\u001b[39m\u001b[38;5;124mHttpHeaders\u001b[39m\u001b[38;5;124m'\u001b[39m])\n\u001b[0;32m---> 44\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43mf\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43margs\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/docker/api/client.py:236\u001b[0m, in \u001b[0;36mAPIClient._get\u001b[0;34m(self, url, **kwargs)\u001b[0m\n\u001b[1;32m 234\u001b[0m \u001b[38;5;129m@update_headers\u001b[39m\n\u001b[1;32m 235\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21m_get\u001b[39m(\u001b[38;5;28mself\u001b[39m, url, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs):\n\u001b[0;32m--> 236\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mget\u001b[49m\u001b[43m(\u001b[49m\u001b[43murl\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_set_request_timeout\u001b[49m\u001b[43m(\u001b[49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/requests/sessions.py:602\u001b[0m, in \u001b[0;36mSession.get\u001b[0;34m(self, url, **kwargs)\u001b[0m\n\u001b[1;32m 594\u001b[0m \u001b[38;5;250m\u001b[39m\u001b[38;5;124mr\u001b[39m\u001b[38;5;124;03m\"\"\"Sends a GET request. Returns :class:`Response` object.\u001b[39;00m\n\u001b[1;32m 595\u001b[0m \n\u001b[1;32m 596\u001b[0m \u001b[38;5;124;03m:param url: URL for the new :class:`Request` object.\u001b[39;00m\n\u001b[1;32m 597\u001b[0m \u001b[38;5;124;03m:param \\*\\*kwargs: Optional arguments that ``request`` takes.\u001b[39;00m\n\u001b[1;32m 598\u001b[0m \u001b[38;5;124;03m:rtype: requests.Response\u001b[39;00m\n\u001b[1;32m 599\u001b[0m \u001b[38;5;124;03m\"\"\"\u001b[39;00m\n\u001b[1;32m 601\u001b[0m kwargs\u001b[38;5;241m.\u001b[39msetdefault(\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mallow_redirects\u001b[39m\u001b[38;5;124m\"\u001b[39m, \u001b[38;5;28;01mTrue\u001b[39;00m)\n\u001b[0;32m--> 602\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrequest\u001b[49m\u001b[43m(\u001b[49m\u001b[38;5;124;43m\"\u001b[39;49m\u001b[38;5;124;43mGET\u001b[39;49m\u001b[38;5;124;43m\"\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43murl\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/requests/sessions.py:589\u001b[0m, in \u001b[0;36mSession.request\u001b[0;34m(self, method, url, params, data, headers, cookies, files, auth, timeout, allow_redirects, proxies, hooks, stream, verify, cert, json)\u001b[0m\n\u001b[1;32m 584\u001b[0m send_kwargs \u001b[38;5;241m=\u001b[39m {\n\u001b[1;32m 585\u001b[0m \u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mtimeout\u001b[39m\u001b[38;5;124m\"\u001b[39m: timeout,\n\u001b[1;32m 586\u001b[0m \u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mallow_redirects\u001b[39m\u001b[38;5;124m\"\u001b[39m: allow_redirects,\n\u001b[1;32m 587\u001b[0m }\n\u001b[1;32m 588\u001b[0m send_kwargs\u001b[38;5;241m.\u001b[39mupdate(settings)\n\u001b[0;32m--> 589\u001b[0m resp \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43msend\u001b[49m\u001b[43m(\u001b[49m\u001b[43mprep\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43msend_kwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 591\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m resp\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/requests/sessions.py:703\u001b[0m, in \u001b[0;36mSession.send\u001b[0;34m(self, request, **kwargs)\u001b[0m\n\u001b[1;32m 700\u001b[0m start \u001b[38;5;241m=\u001b[39m preferred_clock()\n\u001b[1;32m 702\u001b[0m \u001b[38;5;66;03m# Send the request\u001b[39;00m\n\u001b[0;32m--> 703\u001b[0m r \u001b[38;5;241m=\u001b[39m \u001b[43madapter\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43msend\u001b[49m\u001b[43m(\u001b[49m\u001b[43mrequest\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 705\u001b[0m \u001b[38;5;66;03m# Total elapsed time of the request (approximately)\u001b[39;00m\n\u001b[1;32m 706\u001b[0m elapsed \u001b[38;5;241m=\u001b[39m preferred_clock() \u001b[38;5;241m-\u001b[39m start\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/requests/adapters.py:486\u001b[0m, in \u001b[0;36mHTTPAdapter.send\u001b[0;34m(self, request, stream, timeout, verify, cert, proxies)\u001b[0m\n\u001b[1;32m 483\u001b[0m timeout \u001b[38;5;241m=\u001b[39m TimeoutSauce(connect\u001b[38;5;241m=\u001b[39mtimeout, read\u001b[38;5;241m=\u001b[39mtimeout)\n\u001b[1;32m 485\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[0;32m--> 486\u001b[0m resp \u001b[38;5;241m=\u001b[39m \u001b[43mconn\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43murlopen\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m 487\u001b[0m \u001b[43m \u001b[49m\u001b[43mmethod\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mrequest\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mmethod\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 488\u001b[0m \u001b[43m \u001b[49m\u001b[43murl\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43murl\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 489\u001b[0m \u001b[43m \u001b[49m\u001b[43mbody\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mrequest\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbody\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 490\u001b[0m \u001b[43m \u001b[49m\u001b[43mheaders\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mrequest\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mheaders\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 491\u001b[0m \u001b[43m \u001b[49m\u001b[43mredirect\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mFalse\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m 492\u001b[0m \u001b[43m \u001b[49m\u001b[43massert_same_host\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mFalse\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m 493\u001b[0m \u001b[43m \u001b[49m\u001b[43mpreload_content\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mFalse\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m 494\u001b[0m \u001b[43m \u001b[49m\u001b[43mdecode_content\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mFalse\u001b[39;49;00m\u001b[43m,\u001b[49m\n\u001b[1;32m 495\u001b[0m \u001b[43m \u001b[49m\u001b[43mretries\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mmax_retries\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 496\u001b[0m \u001b[43m \u001b[49m\u001b[43mtimeout\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mtimeout\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 497\u001b[0m \u001b[43m \u001b[49m\u001b[43mchunked\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mchunked\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 498\u001b[0m \u001b[43m \u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 500\u001b[0m \u001b[38;5;28;01mexcept\u001b[39;00m (ProtocolError, \u001b[38;5;167;01mOSError\u001b[39;00m) \u001b[38;5;28;01mas\u001b[39;00m err:\n\u001b[1;32m 501\u001b[0m \u001b[38;5;28;01mraise\u001b[39;00m \u001b[38;5;167;01mConnectionError\u001b[39;00m(err, request\u001b[38;5;241m=\u001b[39mrequest)\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/urllib3/connectionpool.py:793\u001b[0m, in \u001b[0;36mHTTPConnectionPool.urlopen\u001b[0;34m(self, method, url, body, headers, retries, redirect, assert_same_host, timeout, pool_timeout, release_conn, chunked, body_pos, preload_content, decode_content, **response_kw)\u001b[0m\n\u001b[1;32m 790\u001b[0m response_conn \u001b[38;5;241m=\u001b[39m conn \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m release_conn \u001b[38;5;28;01melse\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m\n\u001b[1;32m 792\u001b[0m \u001b[38;5;66;03m# Make the request on the HTTPConnection object\u001b[39;00m\n\u001b[0;32m--> 793\u001b[0m response \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_make_request\u001b[49m\u001b[43m(\u001b[49m\n\u001b[1;32m 794\u001b[0m \u001b[43m \u001b[49m\u001b[43mconn\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 795\u001b[0m \u001b[43m \u001b[49m\u001b[43mmethod\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 796\u001b[0m \u001b[43m \u001b[49m\u001b[43murl\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 797\u001b[0m \u001b[43m \u001b[49m\u001b[43mtimeout\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mtimeout_obj\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 798\u001b[0m \u001b[43m \u001b[49m\u001b[43mbody\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mbody\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 799\u001b[0m \u001b[43m \u001b[49m\u001b[43mheaders\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mheaders\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 800\u001b[0m \u001b[43m \u001b[49m\u001b[43mchunked\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mchunked\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 801\u001b[0m \u001b[43m \u001b[49m\u001b[43mretries\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mretries\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 802\u001b[0m \u001b[43m \u001b[49m\u001b[43mresponse_conn\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mresponse_conn\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 803\u001b[0m \u001b[43m \u001b[49m\u001b[43mpreload_content\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mpreload_content\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 804\u001b[0m \u001b[43m \u001b[49m\u001b[43mdecode_content\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mdecode_content\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 805\u001b[0m \u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mresponse_kw\u001b[49m\u001b[43m,\u001b[49m\n\u001b[1;32m 806\u001b[0m \u001b[43m\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 808\u001b[0m \u001b[38;5;66;03m# Everything went great!\u001b[39;00m\n\u001b[1;32m 809\u001b[0m clean_exit \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;01mTrue\u001b[39;00m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/urllib3/connectionpool.py:537\u001b[0m, in \u001b[0;36mHTTPConnectionPool._make_request\u001b[0;34m(self, conn, method, url, body, headers, retries, timeout, chunked, response_conn, preload_content, decode_content, enforce_content_length)\u001b[0m\n\u001b[1;32m 535\u001b[0m \u001b[38;5;66;03m# Receive the response from the server\u001b[39;00m\n\u001b[1;32m 536\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[0;32m--> 537\u001b[0m response \u001b[38;5;241m=\u001b[39m \u001b[43mconn\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mgetresponse\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 538\u001b[0m \u001b[38;5;28;01mexcept\u001b[39;00m (BaseSSLError, \u001b[38;5;167;01mOSError\u001b[39;00m) \u001b[38;5;28;01mas\u001b[39;00m e:\n\u001b[1;32m 539\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_raise_timeout(err\u001b[38;5;241m=\u001b[39me, url\u001b[38;5;241m=\u001b[39murl, timeout_value\u001b[38;5;241m=\u001b[39mread_timeout)\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/site-packages/urllib3/connection.py:466\u001b[0m, in \u001b[0;36mHTTPConnection.getresponse\u001b[0;34m(self)\u001b[0m\n\u001b[1;32m 463\u001b[0m \u001b[38;5;28;01mfrom\u001b[39;00m \u001b[38;5;21;01m.\u001b[39;00m\u001b[38;5;21;01mresponse\u001b[39;00m \u001b[38;5;28;01mimport\u001b[39;00m HTTPResponse\n\u001b[1;32m 465\u001b[0m \u001b[38;5;66;03m# Get the response from http.client.HTTPConnection\u001b[39;00m\n\u001b[0;32m--> 466\u001b[0m httplib_response \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43msuper\u001b[39;49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mgetresponse\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 468\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[1;32m 469\u001b[0m assert_header_parsing(httplib_response\u001b[38;5;241m.\u001b[39mmsg)\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/http/client.py:1375\u001b[0m, in \u001b[0;36mHTTPConnection.getresponse\u001b[0;34m(self)\u001b[0m\n\u001b[1;32m 1373\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[1;32m 1374\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[0;32m-> 1375\u001b[0m \u001b[43mresponse\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mbegin\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 1376\u001b[0m \u001b[38;5;28;01mexcept\u001b[39;00m \u001b[38;5;167;01mConnectionError\u001b[39;00m:\n\u001b[1;32m 1377\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mclose()\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/http/client.py:318\u001b[0m, in \u001b[0;36mHTTPResponse.begin\u001b[0;34m(self)\u001b[0m\n\u001b[1;32m 316\u001b[0m \u001b[38;5;66;03m# read until we get a non-100 response\u001b[39;00m\n\u001b[1;32m 317\u001b[0m \u001b[38;5;28;01mwhile\u001b[39;00m \u001b[38;5;28;01mTrue\u001b[39;00m:\n\u001b[0;32m--> 318\u001b[0m version, status, reason \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_read_status\u001b[49m\u001b[43m(\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 319\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m status \u001b[38;5;241m!=\u001b[39m CONTINUE:\n\u001b[1;32m 320\u001b[0m \u001b[38;5;28;01mbreak\u001b[39;00m\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/http/client.py:279\u001b[0m, in \u001b[0;36mHTTPResponse._read_status\u001b[0;34m(self)\u001b[0m\n\u001b[1;32m 278\u001b[0m \u001b[38;5;28;01mdef\u001b[39;00m \u001b[38;5;21m_read_status\u001b[39m(\u001b[38;5;28mself\u001b[39m):\n\u001b[0;32m--> 279\u001b[0m line \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mstr\u001b[39m(\u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mfp\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mreadline\u001b[49m\u001b[43m(\u001b[49m\u001b[43m_MAXLINE\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m+\u001b[39;49m\u001b[43m \u001b[49m\u001b[38;5;241;43m1\u001b[39;49m\u001b[43m)\u001b[49m, \u001b[38;5;124m\"\u001b[39m\u001b[38;5;124miso-8859-1\u001b[39m\u001b[38;5;124m\"\u001b[39m)\n\u001b[1;32m 280\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m \u001b[38;5;28mlen\u001b[39m(line) \u001b[38;5;241m>\u001b[39m _MAXLINE:\n\u001b[1;32m 281\u001b[0m \u001b[38;5;28;01mraise\u001b[39;00m LineTooLong(\u001b[38;5;124m\"\u001b[39m\u001b[38;5;124mstatus line\u001b[39m\u001b[38;5;124m\"\u001b[39m)\n",
- "File \u001b[0;32m~/miniconda3/envs/pye/lib/python3.10/socket.py:705\u001b[0m, in \u001b[0;36mSocketIO.readinto\u001b[0;34m(self, b)\u001b[0m\n\u001b[1;32m 703\u001b[0m \u001b[38;5;28;01mwhile\u001b[39;00m \u001b[38;5;28;01mTrue\u001b[39;00m:\n\u001b[1;32m 704\u001b[0m \u001b[38;5;28;01mtry\u001b[39;00m:\n\u001b[0;32m--> 705\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_sock\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mrecv_into\u001b[49m\u001b[43m(\u001b[49m\u001b[43mb\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 706\u001b[0m \u001b[38;5;28;01mexcept\u001b[39;00m timeout:\n\u001b[1;32m 707\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_timeout_occurred \u001b[38;5;241m=\u001b[39m \u001b[38;5;28;01mTrue\u001b[39;00m\n",
- "\u001b[0;31mKeyboardInterrupt\u001b[0m: "
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "🏃 Running BLAST\n"
+ ]
+ },
+ {
+ "name": "stderr",
+ "output_type": "stream",
+ "text": [
+ "⬇️ Fetching protein sequences: 100%|██████████| 100/100 [00:06<00:00, 14.97it/s]\n"
]
}
],
@@ -77,27 +58,6 @@
")"
]
},
- {
- "cell_type": "code",
- "execution_count": null,
- "metadata": {},
- "outputs": [
- {
- "ename": "NameError",
- "evalue": "name 'blast_results' is not defined",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[1], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m \u001b[43mblast_results\u001b[49m[\u001b[38;5;241m0\u001b[39m]\u001b[38;5;241m.\u001b[39msource_id\n",
- "\u001b[0;31mNameError\u001b[0m: name 'blast_results' is not defined"
- ]
- }
- ],
- "source": [
- "blast_results[0].source_id"
- ]
- },
{
"cell_type": "markdown",
"metadata": {},
@@ -105,86 +65,53 @@
"## MSA with Clustal Omega"
]
},
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": []
- },
{
"cell_type": "code",
- "execution_count": 3,
+ "execution_count": 4,
"metadata": {},
"outputs": [
{
- "ename": "NameError",
- "evalue": "name 'blast_results' is not defined",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[3], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m alignment \u001b[38;5;241m=\u001b[39m Alignment\u001b[38;5;241m.\u001b[39mfrom_sequences(\u001b[43mblast_results\u001b[49m)\n\u001b[1;32m 2\u001b[0m alignment\u001b[38;5;241m.\u001b[39malign(ClustalOmega)\n",
- "\u001b[0;31mNameError\u001b[0m: name 'blast_results' is not defined"
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "🏃 Running CLUSTALO\n"
]
- }
- ],
- "source": [
- "alignment = Alignment.from_sequences(blast_results)\n",
- "alignment.align(ClustalOmega)"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": null,
- "metadata": {},
- "outputs": [],
- "source": [
- "alignment.apply_standard_numbering()"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": null,
- "metadata": {},
- "outputs": [
+ },
{
"data": {
"text/plain": [
"Alignment(id='alignment0', method='CLUSTALO', consensus='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', input_sequences=[Sequence(id='sequence0', source_id='BAH60832.1', sequence='MSASEMRAASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDNENKELVSQPHNYGHTSE'), Sequence(id='sequence1', source_id='CAI4663910.1', sequence='MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQDRKSHNIRKPSSSPSSKAPSPGVNT'), Sequence(id='sequence2', source_id='EJT44931.1', sequence='MTTPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQDRKNHTVKKPSSSPSSKPPSPGVNI'), Sequence(id='sequence3', source_id='XP_037139093.1', sequence='MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRPSPSARTSFS'), Sequence(id='sequence4', source_id='XP_003680887.1', sequence='MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRSSPSTRSSTS'), Sequence(id='sequence5', source_id='XP_037144827.1', sequence='MSQEYRTRSRSRSFSDQAATQEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIKNSNTNVTTESRRKSPTYTQ'), Sequence(id='sequence6', source_id='AQZ18344.1', sequence='MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG'), Sequence(id='sequence7', source_id='XP_002495560.1', sequence='MDNSDQEVQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR'), Sequence(id='sequence8', source_id='XP_003673548.1', sequence='MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS'), Sequence(id='sequence9', source_id='XP_003958955.1', sequence='MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLKTPRA'), Sequence(id='sequence10', source_id='XP_001644471.1', sequence='MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASASSSASSPSAST'), Sequence(id='sequence11', source_id='XP_003684279.1', sequence='MPYRENRNASSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence12', source_id='SMN18735.1', sequence='MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSSSISPPKSKGTTAS'), Sequence(id='sequence13', source_id='CAD1779387.1', sequence='MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTSSTSTSQVKAKETTAT'), Sequence(id='sequence14', source_id='KAG0666170.1', sequence='MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS'), Sequence(id='sequence15', source_id='XP_022464898.1', sequence='MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERTPVSSQQ'), Sequence(id='sequence16', source_id='XP_003669861.1', sequence='MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK'), Sequence(id='sequence17', source_id='XP_003678517.1', sequence='MASEHRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK'), Sequence(id='sequence18', source_id='KAG0659075.1', sequence='MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSSHGHTSNNNNNNNTPIQASPIAVRSSYNHRHH'), Sequence(id='sequence19', source_id='XP_451758.1', sequence='MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSPKRQVHTPPPSS'), Sequence(id='sequence20', source_id='NP_984991.1', sequence='MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPSEYTHHGRYRQPEHIRNMAEQ'), Sequence(id='sequence21', source_id='XP_017989070.1', sequence='MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVMAASSGYSPTSATVEQGQYRQSERAQHTASEQ'), Sequence(id='sequence22', source_id='KAG0673910.1', sequence='MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVHTPPPSS'), Sequence(id='sequence23', source_id='SMN21971.1', sequence='MNSEKNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL'), Sequence(id='sequence24', source_id='KAG0661436.1', sequence='MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN'), Sequence(id='sequence25', source_id='SCV02624.1', sequence='MSTNEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSRTPSPHRSP'), Sequence(id='sequence26', source_id='SCV99388.1', sequence='MSLATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS'), Sequence(id='sequence27', source_id='CUS20182.1', sequence='MSMVSGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS'), Sequence(id='sequence28', source_id='XP_045933944.1', sequence='MHFQQQQQQHYHTPLRHGSDPAQHITNNSEEHINNYGNNTVDTPQQLRHTSAMTVINSSQAATNNNYSDNNNNTSPVRGTTSTAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN'), Sequence(id='sequence29', source_id='KAA8901327.1', sequence='MSTPSSPSGGGSKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW'), Sequence(id='sequence30', source_id='KAF8417303.1', sequence='MSDSSTIASGSGAGGSYHHQQASTSSAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV'), Sequence(id='sequence31', source_id='KAF3929277.1', sequence='MTTTPPTKRETSPVSPLRASFANLNTEDHSQATAAIRAQAGHTRHESLEKYTRRDSTASENRNEEGYRERGSISSQSGAAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence32', source_id='OEJ86227.1', sequence='MTEYENGQQQQRERIRGQERESYDEQERESYDEQERERIREQERRINNEQQRRVNNEQQRRXNNQQRSTTNDNVSSNKNTHKDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH'), Sequence(id='sequence33', source_id='XP_046060918.1', sequence='MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS'), Sequence(id='sequence34', source_id='EPS36031.1', sequence='MTTTPPTKRDASPVSPLRASFANLNTDDHTSATAAIRAAAGHTRHESLEKYTRRDSTASENRPEEGYRERGSISSQGGSAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence35', source_id='KAI5807151.1', sequence='MHELPLAPSLPPPQSPPTPDRYSQGAARHYHSNSAASAPAMIGDAAGAYYRGSPPPPMPQQPYVPRDRSSESYHNGSSAQQQQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence36', source_id='XP_011117899.1', sequence='MTTTPPTKRESSPVSPLRASFANLNADDHSSATAAIRAAAGHTRHESLEKYTRRDSTASENRNDESYRDRSSVSSQGGSGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR'), Sequence(id='sequence37', source_id='KAI1438264.1', sequence='MEQDLHTTPGADLEPHGLPDDGSISSIEDTPEAASSLNGHETYHQHPQSLDYVVSSSQNTDETDPNAQYETVPATSQAQSISRPPSGLSGAGGDRQAAHSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence38', source_id='XP_022456167.1', sequence='MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV'), Sequence(id='sequence39', source_id='KAF3908940.1', sequence='MTTTPPTKRDVSPVSPLRASFANLNTTDDGQSATAAIRASAGHTRHESLEKYTRRDSTASESRNEDGYRERSSISSQGGSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR'), Sequence(id='sequence40', source_id='XP_006693239.1', sequence='MERDQLAAPAPSESAASDYRDHSLADAEVAPSSDCENNGFHDHHYSQSQHYDQDDAAESEPTARYNTPSGSGQQISRPPSGLSGERGAGYATDQGSRAGSNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV'), Sequence(id='sequence41', source_id='EWC45326.1', sequence='MATTPPTKRDTSPVSPLRASFANLNTTDDGQQSAAAAIRAAAGHTRHESLEKYTRRDSTASESRNDDGYRERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR'), Sequence(id='sequence42', source_id='KAF3930522.1', sequence='MTTTPPTKQGSRNVSPVSPLRASFANLNTTDENHSSATAAIRAAAGHTRHESLEKYTRRDSNASESKNEDGYRERSSVSSQGGSSQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR'), Sequence(id='sequence43', source_id='KAF8249497.1', sequence='MQQHDDDALPQPQTTELPLAPSLPPPVALAHSPPTPRRRNSSPTRHYHSSSNASGAPPYIGSPGSVESAQYYNSQGSPPTPAAPHQQQQFATSRADGGYHNGGGYAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence44', source_id='XP_002174495.1', sequence='MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV'), Sequence(id='sequence45', source_id='PRP83484.1', sequence='MGDQNDTEARIGHSRLPFFIMSGDGEYTGSGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS'), Sequence(id='sequence46', source_id='GAA97202.1', sequence='MASSTSTGAGSSSSRQRQESYRSSHSQQSSSQHAPAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI'), Sequence(id='sequence47', source_id='OBA26219.1', sequence='MESMLQSHNRRRHTNSMSISGSSNNNVHSELRQNNNNRISSMPSSQPASNSNNKPVDNIKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR'), Sequence(id='sequence48', source_id='KAI1823332.1', sequence='MEQDFHAVPAPDSEPHDHPDDGLGGLEESPDIAPGSNGHELYHQHPQSLDYVISNNQNIDDVDPNAPYEAVATTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence49', source_id='CDO57487.1', sequence='MSIPSIYPNHKPTGMYTGQFISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW'), Sequence(id='sequence50', source_id='KAI2629167.1', sequence='MDQDPMATPIPHDVHDDTLGGIEGSMHLPNEPHNHETHHRQSQSLDQGLANNAHPDEVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence51', source_id='KAI5811198.1', sequence='MSNDPLPTIPSATSSTVDLSNGNDGSAQNENEPPHRSQHHTGMTSIHLNDPTSQSNAAASYSQTHSGATMLSSGSGATGSFQQAGGPSSGGPAGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV'), Sequence(id='sequence52', source_id='KAG9017701.1', sequence='MSTAASGSGAPPATPLSAASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ'), Sequence(id='sequence53', source_id='OTA67948.1', sequence='MHFPGHLPDEPSSSSHEPHHRQSQSLDQGLANSAHPHPHPDDIDPNAQYEAQQYDPPQQSTQRPPSSMSSTGERQYTEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence54', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVPAAAAAQVPLPHSLSPPLQIDPHDDTLSSAGTVSHQALPDHNNFHEHNGYHDQPQHPIQFQPLDHSVNNSPRSYYPADQTDSEPTARYATPPVAAPAISRPSSGLSGQGAGYGADHVSRAGSNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence55', source_id='ORX96310.1', sequence='MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID'), Sequence(id='sequence56', source_id='XP_028477951.1', sequence='MTDPGYASSGSGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL'), Sequence(id='sequence57', source_id='XP_024666830.1', sequence='MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW'), Sequence(id='sequence58', source_id='KAI0099584.1', sequence='MHIPGHLPGESSSSHEPHHRQSQSLDQGLANSAPPLPDDIDPNAQYEAHQYDPPQQPVQRPASSMSSTGERQYNEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence59', source_id='KAI1801530.1', sequence='MHIAGEPGVHEPHHRQSRSLDQGLANSAHADDIDTHAVDPHAIDPIAVDHNAQYEAHSYEPPAQSMSRPASSSGTGERHLNGEASREGNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence60', source_id='KAF9351078.1', sequence='MSDTPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY'), Sequence(id='sequence61', source_id='KAF9160900.1', sequence='MAATSESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI'), Sequence(id='sequence62', source_id='KAG0263740.1', sequence='MAAAGDSGKKSSSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK'), Sequence(id='sequence63', source_id='KAI1135662.1', sequence='MEQDPVAAPVPHDIHEDTIGGIEGSMHIPAEPSTSHEPHRHRQSQSLDRGLASSKHPEDIDPNAQYDTPQYDPPQQSMPRPASSSSAGERHYAEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence64', source_id='XP_045969802.1', sequence='MTTTPPPLENNGSLPSHIDIDVAATPRQEHYTSSSDPSLAFSPQDSNSPSRANIGDDQRHSGTPPLSQSQLYGNGGGMNSFTSAAGAAAGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence65', source_id='KAI1414505.1', sequence='MHFSGEPSSSHEPLHRQSQSLDQGLANSAHPHPDDIDPNAQYEAHQYDPPQQSMQRPTSSMSSGGERHYTEQAPRESNGTDRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence66', source_id='KAG0239750.1', sequence='MATLGDSGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY'), Sequence(id='sequence67', source_id='XP_044688071.1', sequence='MTTTPPPPENNGSLPSHIDVDVAATPRQEHYTSSDPSLTFSPQDSNSPSRAIGDERNSGTPPLSQSQLYGNGGGMNNFTSAAAAAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence68', source_id='RPB01516.1', sequence='MTTTPPLLFSPSPPPPLPDSLYPDEPEEVTTPTATLPPPPPSPPPRQPSPARHQHSGSAPATVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGGGGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence69', source_id='KAG0236582.1', sequence='MAASADSARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS'), Sequence(id='sequence70', source_id='KAH6640987.1', sequence='MEQDQAISPAYAVAPDSALAPARIPSPAGFPTDPHDDTLSGVESVTHQAVPDHHIHEHNGFHEQQHISQLQPLDHNVTNSPRSPYPTDTTDSEPTARYATPPIQAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence71', source_id='XP_002493958.1', sequence='MPDSPRRNQHRRSHSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI'), Sequence(id='sequence72', source_id='KAA8914877.1', sequence='MTTTPPPSRTSTSDMDHSARTPSSSSSSIPEEYIHTELRLAPSLSSLQSPPTPDRGSPSRYHHSHSNSATSAPSDGASYYGGSPPAMRDRDREGYYGNGAGAAGGSGGGAGSSAYNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV'), Sequence(id='sequence73', source_id='XP_018701974.1', sequence='METDDVPAATLHDNLDDTLGGLDGSPQVPSSSHYSNHHHDHQYQNPHHSNNDTHEHEPQSPGGGPSHHQQQHHDEDPPCTRYTPPAPGSSAPASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence74', source_id='KAI2643608.1', sequence='MEHDLHGAPVSGLEPHAHHDDDSLNDADEHSDIASSLNGHESYHQPSQSLDYVLSHGQDTDEADPNSQYETQPTTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence75', source_id='KAG0125076.1', sequence='MTTTPPPLFSPSPPPPLPDSLCPDDPEEVTTPTSNLPPPPLPSPPPRQPSPVRHHHSGPAPAAVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGSGGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence76', source_id='KAH9904989.1', sequence='MEQDPVAAAVPQDGYDDTLGGIEGSPHVGPTQINREKRHQQSQSLDNGLPNNGHADEIDPNARYDTPPNPLQPHSISRPPSGLSGAGDRHNAYSDHASRGSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence77', source_id='VEU24358.1', sequence='MDNRSVSTRIPRSHSTSEALSEEPARSVSSTVDGYDNYYGHQHHHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV'), Sequence(id='sequence78', source_id='KAI1283572.1', sequence='MDTMEQDFHAAPIPGPHEHLDEPLPDTFADVEGGPHVSPSQNGHEVYHHHHQQSQSLDHGLASSQNHDEADLNGRYETPPSTAHPQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence79', source_id='KAI1500557.1', sequence='MMEHDPAFATAPGPHNGIDDMLGGIEGSPTLASGQNGHETYHHHHSQSFDQEIPLNENPDDMDTTAQYDTPPVTAQPQSISRPPSALDGAAGERHASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC'), Sequence(id='sequence80', source_id='KAI2623093.1', sequence='MDQDPITTPVQAPAQDPTPHELHEDTFGGIEGSMHLSGEPGTPEAHHRQSQSLDQGLANSVHPDEVDPNTQYEAHQYDAPPQSMPRPASSMSGAGERQYPEHASRESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence81', source_id='NP_593285.1', sequence='MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR'), Sequence(id='sequence82', source_id='KAI0431960.1', sequence='MDTMEQDFHAAPIPGPHEHLDETLPDTLADVEGAPHVSPSQNGHEVYHHHQQSHSLDQGLANSQTSDEPDLNGRYETPPSTGHAQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence83', source_id='KAH8926511.1', sequence='MSDSAGPLALEKGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV'), Sequence(id='sequence84', source_id='RMJ24013.1', sequence='MNPSYHNGYSSDSHAQYSTGPAGFNPPVHDSTSQDAEQTRLTFSPSITQQPQPPSLSRPSSAFSSGPERHGASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV'), Sequence(id='sequence85', source_id='KAF8931046.1', sequence='MAATGESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN'), Sequence(id='sequence86', source_id='ODQ76250.1', sequence='MSSAAPNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV'), Sequence(id='sequence87', source_id='KXJ93426.1', sequence='MDQEPAALPPTRNPLDVAPDDTLGGIESSPRVYSDPESTIRTHHHSQSLDQGLASSAHYQHNSEDMDHQTRQDTPPIPQQPQSISRPPSGLSGAGDRQPAQYSDHASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence88', source_id='XP_051368163.1', sequence='MDQDLLGTPTAPHDTLDDALAGVEGPLHLASESGNLEPHHRQSQSLDRGLANNAQVDDFDTAVPFDSPQYDTPPPAMQRPASSDSAAGEKQLAEHASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence89', source_id='GES63634.1', sequence='METIHNLNTGVSEPVEQQPQESAFEASPVSHPAGSTDEPTSASVYHRSGYNSDSHAQYSSLATHQPQPPTSSRPSSGLSGPERYGPSQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV'), Sequence(id='sequence90', source_id='RPA74746.1', sequence='MADHHEGSSHSYDRTSHSSRPATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV'), Sequence(id='sequence91', source_id='XP_024675402.1', sequence='MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPAGPYPSHVESVPPEVIPSASTYHAGYSSDSHANYSSNAVDFNSGSEYPPQPRAELPRAQEAVPSMMHPPAAPSSSRPSSGLSSGPDRLGSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL'), Sequence(id='sequence92', source_id='KAH6850716.1', sequence='MEQEQAFNPAYTMAPDPALAPAPIPAPISSPVGLPTDPHDDTLSGVESVTHQALPDHNIHDHNGFHEQQHLVQLQPLDHSVNNSPRSPYPTDTTDSEPTARYATPPIPAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence93', source_id='PHH71636.1', sequence='MEHQQPELDQQPPPLHAAHDSLDDTLGGIEGSPHVAAANNGFHQQSQSLDSAVPNSPRYDDDAANRHTPPVSSAPSLSRPGSQMSNPSSSNPPQQMHGNDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence94', source_id='KAJ3562589.1', sequence='MDTMEQDLHTTPIPGVHEHHHLDDALPDPHADVDARPHSAPGQNGHEVYHQQSHSLDQGIAHGQHPDEADLNGRYDTPPSATHPQSISRPPSGLSGAGGDRQTTYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV'), Sequence(id='sequence95', source_id='RDA84390.1', sequence='MDHQPAADQEQPQELPRPASHDGLDDTLGGIEGSPHPVASSNGFHAHQEAPGSPRYDDDNAARQTPPVSAPLSRPGSQMSNPPQHASGSDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence96', source_id='XP_007413704.1', sequence='MSNMTSSTGPAGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV'), Sequence(id='sequence97', source_id='KAI0376630.1', sequence='MHLPNEPHNHETHHRQSQSLDQGLANNVHPDDVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence98', source_id='XP_047831721.1', sequence='MEQDFHTAPIPGPREHLDALPDTHDTHADVVARPHTAPDQNGHEVYHQQSQSLDQGLSDSQHHDDADVAGRYETHPSTTHPQSISRPPSGLSGAGGDRQATYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence99', source_id='KAI9294962.1', sequence='MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE')], aligned_sequences=[Sequence(id='sequence100', source_id='BAH60832.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSA------------SE-----MR-----A---------ASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDN-ENKELV---------SQPHNYGHTSE---------------------------------'), Sequence(id='sequence101', source_id='CAI4663910.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------A-TPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQD--RKSHNIRKPSS-------------------SPSSKAPSPGVNT-----------------------'), Sequence(id='sequence102', source_id='EJT44931.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------T-TPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQD--RKNHTVKKPSS-------------------SPSSKPPSPGVNI-----------------------'), Sequence(id='sequence103', source_id='XP_037139093.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRP--SPSARTSFS--------------------------------------------------------'), Sequence(id='sequence104', source_id='XP_003680887.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRS--SPSTRSSTS--------------------------------------------------------'), Sequence(id='sequence105', source_id='XP_037144827.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MSQEYR----T---------RSRSRSF------------SD-----QA-----AT-----QEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIK--NSNTNVTTES-----------------------RRKSPTYTQ-----------------------'), Sequence(id='sequence106', source_id='AQZ18344.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG----------------------------------------------------------------------'), Sequence(id='sequence107', source_id='XP_002495560.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDN------------SD-----QE-------------VQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR-----------------------------------------------------------------------'), Sequence(id='sequence108', source_id='XP_003673548.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS----------------------------------------------------------------'), Sequence(id='sequence109', source_id='XP_003958955.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLK-TP-------RA---------------------------------------------------'), Sequence(id='sequence110', source_id='XP_001644471.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASAS--SSA-------S-------------------SPS-------AST-----------------------'), Sequence(id='sequence111', source_id='XP_003684279.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPY------------RE-----NR-----N---------A-SSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence112', source_id='SMN18735.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSS---SISPPKSKGTTAS--------------------------------------------'), Sequence(id='sequence113', source_id='CAD1779387.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTS---STSTSQVKAKETTAT------------------------------------------'), Sequence(id='sequence114', source_id='KAG0666170.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS-------------------------------------------'), Sequence(id='sequence115', source_id='XP_022464898.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERT-PVSSQQ-----------------------------------------------------'), Sequence(id='sequence116', source_id='XP_003669861.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK---------------------------------------------------------------------------'), Sequence(id='sequence117', source_id='XP_003678517.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------------------------SE----------------------HRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK----------------------------------------------------------------------'), Sequence(id='sequence118', source_id='KAG0659075.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSS--------HG--HTSNNNNNNNTPIQASPIAVRSSYNHR----HH-------------'), Sequence(id='sequence119', source_id='XP_451758.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSP-KRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence120', source_id='NP_984991.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPS--------------------E------YTHHGRYRQ--------PEHIRNMAE----------Q--------'), Sequence(id='sequence121', source_id='XP_017989070.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVM-----AASSGYSPTSA------TVEQGQYRQ--------SERAQHTAS----------EQ-------'), Sequence(id='sequence122', source_id='KAG0673910.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence123', source_id='SMN21971.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSE----KNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL-------------------------------------------------------------------------'), Sequence(id='sequence124', source_id='KAG0661436.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN--------------------------------------------------------------------------'), Sequence(id='sequence125', source_id='SCV02624.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MST----NEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSR-TPSPHRSP------------------------------------------------------'), Sequence(id='sequence126', source_id='SCV99388.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSL----ATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS-----------------------------------------------------------------------'), Sequence(id='sequence127', source_id='CUS20182.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----SMV----SGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS----------------------------------------------------------------'), Sequence(id='sequence128', source_id='XP_045933944.1', sequence='-------------------------------------MHFQQ----------------------------------------------------------------------QQQQHYHTPLRHGSDPAQ-HITNNSEEHINN--------YGNNTVDTPQQLRHTS---------AMTVINS---SQAATNNNYSDN---NNNT-SPVRG-----TTS----TAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN--------------------------------------------------------------------------'), Sequence(id='sequence129', source_id='KAA8901327.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPS-----S------PSG-----------GG---------------------------SKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence130', source_id='KAF8417303.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-SSTIA-------------SGSGAGGSYHHQQA------STS-------------SAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence131', source_id='KAF3929277.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RETSP----VSPLRASF--ANLN--------TEDHS---------QATAAIR---AQ---------------AGHTR-HESL--EKYTRR-DSTASE-NRNEEGY----------------------RERGSISSQSGAAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence132', source_id='OEJ86227.1', sequence='------------------------------------MTEYEN----------------------------------------------G----QQQQ---------RERIRGQERESYDEQERESYDEQERERIREQERRINN--------EQQRRVNNEQQ--------------------------RRXNNQQRST---TNDN-VSSNK-----NTH----KDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH-------------------------------------------------------------------------'), Sequence(id='sequence133', source_id='XP_046060918.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS-----------------------------------------------------------------'), Sequence(id='sequence134', source_id='EPS36031.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDASP----VSPLRASF--ANLN--------TDDHT---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRPEEGY----------------------RERGSISSQGGSAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence135', source_id='KAI5807151.1', sequence='--------------------------------------------------------------------------MHELPLAPSLPPPQ----SPPTPDR----------YSQGAARHY---HSNSAAS-A-----PAMIG-----------DA-------AGAYYRGSPPPPMPQQPYVP-R----D-RS-SESYHNGSS--------------------AQQ-QQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence136', source_id='XP_011117899.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RESSP----VSPLRASF--ANLN--------ADDHS---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRNDESY----------------------RDRSSVSSQG-GSG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR----------------------------------------------------------------------------'), Sequence(id='sequence137', source_id='KAI1438264.1', sequence='---------------------------------------MEQDLHTTPGADLE----------P--HGLPDD---GSI---------SSIEDTPEA--------AS--SLNGHETYHQ---HPQSLDYVV-----SSS---------------QNTDETDPNAQYET-VPATSQAQSISR-PPSGLSGAGGDRQAA------------------------HSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence138', source_id='XP_022456167.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV---------------------------------------------------------------------------------'), Sequence(id='sequence139', source_id='KAF3908940.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDVSP----VSPLRASF--ANLN--------TTDDGQS--------ATAAIR---AS---------------AGHTR-HESL--EKYTRR-DSTASE-SRNEDGY----------------------RERSSISSQG-GSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence140', source_id='XP_006693239.1', sequence='---------------------------------------MERDQLAAPAPSE------------------S-----AA---------SDYRDHSLADAEVAPSSDCE--NNGFHDHHY--SQSQHYDQ-------DDAAESE---PT---------------ARYNT-PSGS--GQQISR-PPSGLS-GERGAGYATDQGSRAG------------SNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV---------------------------------------------------------------------------------'), Sequence(id='sequence141', source_id='EWC45326.1', sequence='---------------------------------------MATTPP-------------------------------TK------------RDTSP----VSPLRASF--ANLN--------TTDDGQQ-------SAAAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-SRNDDGY----------------------RERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR----------------------------------------------------------------------------'), Sequence(id='sequence142', source_id='KAF3930522.1', sequence='---------------------------------------MTTTPP-------------------------------TK---------QGSRNVSP----VSPLRASF--ANLN--------TTDENHS-------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSNASE-SKNEDGY----------------------RERSSVSSQGGS--SQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR----------------------------------------------------------------------------'), Sequence(id='sequence143', source_id='KAF8249497.1', sequence='-----------------------------------------------------MQ------Q-HDDDALPQP-QTTELPLAPSLPPPVALAHSPPTPRR----------RNSSPTRHY---HSSSNASGA-----PPYIG-----------SP---GSVESAQYYNSQGSPPTPAAPHQQ-QQFATS-RA-DGGYHNGGG-------------------------YAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence144', source_id='XP_002174495.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence145', source_id='PRP83484.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------MG-----------DQ---NDTE-------------ARIGHSR-LPFFIM-SG-DGEYTG-----------------------------SGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS--------------------------------------------------------------------------------'), Sequence(id='sequence146', source_id='GAA97202.1', sequence='-------------------------------------------------------------------------------------------------------------------------MASSTSTG---------AG-----------SS---SSRQRQESYRSS--------------------------HSQQSS--------------------SQH-APAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI---------------------------------------------------------------------------------'), Sequence(id='sequence147', source_id='OBA26219.1', sequence='------------------------------------MESML-------------------------------------------------------------------------------------QSHNRRR-HTNSMSISG--------SSNNNVHSELRQNNNN---------RISSMPS---SQPASN----------SNN-KPVDN-----IKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR------------------------------------------------------------------------'), Sequence(id='sequence148', source_id='KAI1823332.1', sequence='---------------------------------------MEQDFHAVPAPDSE----------P--HDHPDD---G-L---------GGLEESPDI--------AP--GSNGHELYHQ---HPQSLDYVI-----SNN---------------QNIDDVDPNAPYEA-VATTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence149', source_id='CDO57487.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPS-----IYPNH-KPTGM--------YTGQ-----------------------FISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence150', source_id='KAI2629167.1', sequence='---------------------------------------MDQD--------PM----------A--TPIPHDVHDDTL---------GGIEGSMHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNA---------------HPDEVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence151', source_id='KAI5811198.1', sequence='---------------------------------------MSNDPL----PTIP----------SA-TSSTVD----LS---------NG--NDGSA---QNE---N---EPPHRSQHH--TGM------------TSIHL-----NDPTSQSNAA---ASYSQTHSG-ATMLS-------------SGSGATGSFQQAGG------PSSGGP-----AGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence152', source_id='KAG9017701.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAASGSGAPPAT--------------------PLS-AASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ---------------------------------------------------------------------------------'), Sequence(id='sequence153', source_id='OTA67948.1', sequence='-----------------------------------------------------------------------------------------MHFPGHLP---------DEPSSSSHEPHH--RQSQSLDQGL-----ANSAHP-----------HPHPDDIDPNAQYEA-QQYDPPQQSTQR-PPSSMSS-TGERQY---------------------TEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence154', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVP---A-----------AAAAQVPLPH----------SLSPPLQIDPHDDTL---------SSAGTVSHQ---ALPDHNNFHEHNGYHD------QPQHPIQFQ-----PLDHSVN---NSPRSYYPADQTDSEPTARYAT-PPVA--APAISR-PSSGLSGQGAGYGAD--HVSRAG-----------------SNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence155', source_id='ORX96310.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID---------------------------------------------------------------------------------'), Sequence(id='sequence156', source_id='XP_028477951.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTD-P--------------------------------GYASSG-SGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL---------------------------------------------------------------------------------'), Sequence(id='sequence157', source_id='XP_024666830.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence158', source_id='KAI0099584.1', sequence='-----------------------------------------------------------------------------------------MHIPGHLP---------GES-SSSHEPHH--RQSQSLDQGL-----ANSAP-------------PLPDDIDPNAQYEA-HQYDPPQQPVQR-PASSMSS-TGERQY---------------------NEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence159', source_id='KAI1801530.1', sequence='---------------------------------------------------------------------------------------------MHIA---------GEPGV--HEPHH--RQSRSLDQGL-----ANSAHADDIDTHAVDPHAIDPIAVDHNAQYEA-HSYEPPAQSMSR-PASS--SGTGERHL---------------------NGE--ASREGNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence160', source_id='KAF9351078.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-------------------------TPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence161', source_id='KAF9160900.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATS-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI-----------------------------------------------------------------------'), Sequence(id='sequence162', source_id='KAG0263740.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAGD-------------------------SGKKS--SSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK---------------------------------------------------------------------------------'), Sequence(id='sequence163', source_id='KAI1135662.1', sequence='-----------------------------------------------MEQDPV----------A--APVPHDIHEDTI---------GGIEGSMHIP---------AEPSTSHEPHRH--RQSQSLDRGL-----ASSK---------------HPEDIDPNAQYDT-PQYDPPQQSMPR-PASS-SS-AGERHY---------------------AEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence164', source_id='XP_045969802.1', sequence='---------------------------------------MTTTPP----PLEN----------NGSLPSHID----ID---------VA---------------------ATPRQEHY--TSSSD----------PSLAFSP---QDSNSPSRAN---IGDDQRHSG-TPPLSQSQLY--------GNGGGMNSFTSAAG------AA----------------AGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence165', source_id='KAI1414505.1', sequence='-----------------------------------------------------------------------------------------MHFSGE--------------PSSSHEPLH--RQSQSLDQGL-----ANSAHP-------------HPDDIDPNAQYEA-HQYDPPQQSMQR-PTSSMSS-GGERHY---------------------TEQ--APRESNGT-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence166', source_id='KAG0239750.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATLGD-------------------------SGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence167', source_id='XP_044688071.1', sequence='---------------------------------------MTTTPP----PPEN----------NGSLPSHID----VD---------VA---------------------ATPRQEHY--TS-SD----------PSLTFSP---QDSNSPSRAI-----GDERNSG-TPPLSQSQLY--------GNGGGMNNFTSAAA------------------------AAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence168', source_id='RPB01516.1', sequence='---------------------------------------MTTTPPLLFSPSP-------PPP-LPDSLYPDEPEEVTTPTA-TLPPPP------PSPPP----------RQPSPARHQ---HSGSAPA---------TVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGG-----------------------------GGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence169', source_id='KAG0236582.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-----------------------------SADS--ARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS----------------------------------------------------------------------------------'), Sequence(id='sequence170', source_id='KAH6640987.1', sequence='MEQD-QAIS------PAYAVAPDSALA------------------PARIP--------------SPAGFPTDPHDDTL---------SGVESVTHQ---AVPDHH-IHEHNGFHE------Q-QHISQLQ-----PLDHNVT---NSPRSPYPTDTTDSEPTARYAT-PPIQ--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence171', source_id='XP_002493958.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSPR-------------------RNQHRRS----------------------HSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI---------------------------------------------------------------------------------'), Sequence(id='sequence172', source_id='KAA8914877.1', sequence='---------------------------------------MTTTPPPSRTSTSDMDHSARTPS-SSSSSIPEEYIHTELRLAPS----LSSLQSPPTPDR----------GSPSRYHHS---HSNSATSAP----------------------------SDGASYYGGSPPA-MRDRD-RE-GYYGNGAGA-AGGSGGGAG--------------------SSA-YNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence173', source_id='XP_018701974.1', sequence='---------------------------------------METDDV--PAATLH----------D-----NLD----DT---------LG----GLDGSPQVPSSSHY--SNHHHDHQY--QNPHHSNN-------DTHEHEP---QSPG-GGPSH---HQ-QQHHDE-DPPC--TRY-TP-PAPGSS-APASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence174', source_id='KAI2643608.1', sequence='---------------------------------------MEHDLHGAPVSGLE----------P--HAHHDD---DSL---------NDADEHSDI--------AS--SLNGHESYHQ---PSQSLDYVL-----SHG---------------QDTDEADPNSQYET-QPTTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence175', source_id='KAG0125076.1', sequence='---------------------------------------MTTTPPPLFSPSP-------PPP-LPDSLCPDDPEEVTTPTS-NLPPPP-----LPSPPP----------RQPSPVRHH---HSGPAPA---------AVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGS-----------------------------GGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence176', source_id='KAH9904989.1', sequence='---------------------------------------MEQDPV--------------------AAAVPQDGYDDTLG---------GIEGSPHVGPT----------QINREKRHQ---QSQSLDNGL-----P-NNG-----------HA---DEIDPNARYDTPPN-PLQPHSISR-PPSGLS-GAGDRHNAYSDH--------------------ASR-GSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence177', source_id='VEU24358.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------MDNRSVSTRIPRSHSTSEALSEEPARSVSSTV--DGYDNYY-----------GHQH---HHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence178', source_id='KAI1283572.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--EPLPDTF---------ADVEGGPHV--------SP--SQNGHEVYHHHHQQSQSLDHGL-----ASS---------------QNHDEADLNGRYET-PPSTAHPQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence179', source_id='KAI1500557.1', sequence='--------------------------------------MMEHDPAFATAPGPH----------N-----GIDD--------------------MLGGIEGSPTLASG--QNGHETYHH--HHSQSFDQ-------E----IP---LN---ENPDD---MDTTAQYDT-PPVTAQPQSISR-PPSALD-GAAGER-----------------------HASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence180', source_id='KAI2623093.1', sequence='---------------------------------------MDQDPITTPVQAPA----------Q--DPTPHELHEDTF---------GGIEGSMHLS---------GEPGT--PEAHH--RQSQSLDQGL-----ANSV---------------HPDEVDPNTQYEA-HQYDAPPQSMPR-PASSMSG-AGERQY---------------------PEH--ASRESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence181', source_id='NP_593285.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR---------------------------------------------------------------------------------'), Sequence(id='sequence182', source_id='KAI0431960.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--ETLPDTL---------ADVEGAPHV--------SP--SQNGHEVYHHH-QQSHSLDQGL-----ANS---------------QTSDEPDLNGRYET-PPSTGHAQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence183', source_id='KAH8926511.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSAGP-----LALE-----KGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV---------------------------------------------------------------------------------'), Sequence(id='sequence184', source_id='RMJ24013.1', sequence='-----------------------------------------MNPS-------------------------------YH---------NGYSSDSHA--QYSTGPAGF--NPPVHDS-----TSQDAEQ-------TRLTFSP---SI---------------TQQPQ-PPSL---SRPS---SAFSS-GPERHG-------------------------ASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV---------------------------------------------------------------------------------'), Sequence(id='sequence185', source_id='KAF8931046.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATG-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN---------------------------------------------------------------------------------'), Sequence(id='sequence186', source_id='ODQ76250.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS------AA----------------PNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV---------------------------------------------------------------------------------'), Sequence(id='sequence187', source_id='KXJ93426.1', sequence='---------------------------------------MDQEPAAL------------PPTRNPLDVAPDD----TL---------GGIESSPRVYSD----------PESTIRTHH---HSQSLDQGL-----ASSAH-----------YQHNSEDMD-HQTRQDTPPIPQQPQSISR-PPSGLSGAGDRQPAQYSDH--------------------ASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence188', source_id='XP_051368163.1', sequence='---------------------------------------MDQDLLG-----------------T--PTAPHDTLDDAL---------AGVEGPLHLA---------SESGN--LEPHH--RQSQSLDRGL-----ANNAQVDDF---------------DTAVPFDS-PQYDTPPPAMQR-PASSD-SAAGEKQL---------------------AEH--ASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence189', source_id='GES63634.1', sequence='-------METIHNL--NTGV-SEPVEQQP------QESAFEASPVSHPAGSTD----------E-----PTSASVYHR---------SGYNSDSHA--QYSSLA----------------------------------------------------------THQPQ-PP------TSSR-PSSGLS-GPERYGP----------------------SQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV---------------------------------------------------------------------------------'), Sequence(id='sequence190', source_id='RPA74746.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------M---------------ADHHE-GSSH---SYDR---TSHSS-RP-------------------------------ATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence191', source_id='XP_024675402.1', sequence='-------MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPA-GPYPSHV----------ESVPPEVIPSASTYH---------AGYSSDSHAN--YSSNAVDF--NS--------------------------GSEYP---PQPRAELPRA---QEAVPSMMH-PPAA---PSSSR-PSSGLSSGPDRL-----------------------GSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL---------------------------------------------------------------------------------'), Sequence(id='sequence192', source_id='KAH6850716.1', sequence='MEQE-QAFN------PAYTMAPDPALA------------------PAPIPAPI----------SSPVGLPTDPHDDTL---------SGVESVTHQ---ALPDHN-IHDHNGFHE------Q-QHLVQLQ-----PLDHSVN---NSPRSPYPTDTTDSEPTARYAT-PPIP--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence193', source_id='PHH71636.1', sequence='---------------------------------------MEHQQPE-LDQ--Q----------PPPLHAAHDSLDDTL---------GGIEGSPHVAA----------ANNGFHQ------QSQSLDSAV-----P---------NSPR--------YDDDAANRHT-P-PVSSAPSLSR-PGSQMS-----------------NPSSSNPPQQMHG----NDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence194', source_id='KAJ3562589.1', sequence='------------------------------------MDTMEQDLHTTPIPGVH----------E--HHHLDDALPDPH---------ADVDARPHS--------AP--GQNGHEVYH---QQSHSLDQGI-----AHG---------------QHPDEADLNGRYDT-PPSATHPQSISR-PPSGLSGAGGDRQTT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV--------------------------------------------------------------------------------'), Sequence(id='sequence195', source_id='RDA84390.1', sequence='---------------------------------------MDHQPAA-DQEQPQ----------ELPRPASHDGLDDTL---------GGIEGSPHPVA----------SSNGFHA------HQ-----EA-----P---------GSPR--------YDDDNAARQT-P-PVSA--PLSR-PGSQMS-----------------N-----PPQHASG----SDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence196', source_id='XP_007413704.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNMTSSTGP-----AGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV---------------------------------------------------------------------------------'), Sequence(id='sequence197', source_id='KAI0376630.1', sequence='---------------------------------------------------------------------------------------------MHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNV---------------HPDDVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence198', source_id='XP_047831721.1', sequence='---------------------------------------MEQDFHTAPIPGPR----------E--HLDALPDTHDTH---------ADVVARPHT--------AP--DQNGHEVYH---QQSQSLDQGL-----SDS---------------QHHDDADVAGRYET-HPSTTHPQSISR-PPSGLSGAGGDRQAT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence199', source_id='KAI9294962.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE-------------------------------------------------------------------------------')], standard_numberings=[StandardNumbering(id='standardnumbering0', reference_id='BAH60832.1', numbered_id='CAI4663910.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', 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'175.368', '176.369', '177.370', '178.371', '179.372', '180.373', '181.374', '182.375', '183.376', '184.377', '185.378', '186.379', '187.380', '188.381', '189.382', '190.383', '191.384', '192.385', '193.386', '194.387', '195.388', '196.389', '197.390', '198.391', '199.392', '200.393', '201.394', '202.395', '203.396', '204.397', '205.398', '206.399', '207.400', '208.401', '209.402', '210.403', '211.404', '212.405', '213.406', '214.407', '215.408', '216.409', '217.410', '218.411', '219', '220', '221', '222', '223', '224', '225', '226', '227', '228', '229', '230', '231', '232', '233', '234', '235', '236', '237', '237.412', '238', '239', '240', '241', '242', '243', '243.413', '243.414', '243.415', '243.416', '243.417', '243.418', '243.419', '243.420', '243.421', '244', '245', '246', '247', '248', '249', '250', '251', '252', '253', '254', '254.422', '254.423', '254.424', '254.425', '254.426', '254.427', '254.428', '254.429', '254.430', '254.431', '254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454'])])"
]
},
- "execution_count": 9,
+ "execution_count": 4,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
- "alignment"
+ "alignment = Alignment.from_sequences(blast_results)\n",
+ "alignment.align(ClustalOmega)"
]
},
{
"cell_type": "code",
- "execution_count": 1,
+ "execution_count": 5,
"metadata": {},
"outputs": [],
"source": [
- "%reload_ext autoreload\n",
- "%autoreload 2\n",
- "from pyeed.core import ProteinInfo\n",
- "from pyeed.core import Alignment\n",
- "from pyeed.aligners import ClustalOmega\n",
- "from pyeed.aligners import PairwiseAligner"
+ "alignment.apply_standard_numbering()"
]
},
{
"cell_type": "code",
- "execution_count": 2,
+ "execution_count": 15,
"metadata": {},
"outputs": [
{
"name": "stderr",
"output_type": "stream",
"text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 44.96it/s]\n"
+ "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 41.51it/s]\n"
]
},
{
@@ -201,40 +128,39 @@
"sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
"\n",
"# Create and run alignment\n",
- "alignment = Alignment.from_sequences(sequences, aligner=ClustalOmega)"
+ "alignment = Alignment.from_sequences(blast_results, aligner=ClustalOmega)"
]
},
{
"cell_type": "code",
- "execution_count": 1,
+ "execution_count": 14,
"metadata": {},
"outputs": [
{
- "ename": "NameError",
- "evalue": "name 'alignment' is not defined",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[1], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m \u001b[38;5;28mprint\u001b[39m(\u001b[43malignment\u001b[49m)\n",
- "\u001b[0;31mNameError\u001b[0m: name 'alignment' is not defined"
- ]
+ "data": {
+ "text/plain": [
+ "Alignment(id='alignment4', method='CLUSTALO', consensus='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', input_sequences=[Sequence(id='sequence228', source_id='BAH60832.1', sequence='MSASEMRAASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDNENKELVSQPHNYGHTSE'), Sequence(id='sequence229', source_id='CAI4663910.1', sequence='MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQDRKSHNIRKPSSSPSSKAPSPGVNT'), Sequence(id='sequence230', source_id='EJT44931.1', sequence='MTTPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQDRKNHTVKKPSSSPSSKPPSPGVNI'), Sequence(id='sequence231', source_id='XP_037139093.1', sequence='MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRPSPSARTSFS'), Sequence(id='sequence232', source_id='XP_003680887.1', sequence='MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRSSPSTRSSTS'), Sequence(id='sequence233', source_id='XP_037144827.1', sequence='MSQEYRTRSRSRSFSDQAATQEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIKNSNTNVTTESRRKSPTYTQ'), Sequence(id='sequence234', source_id='AQZ18344.1', sequence='MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG'), Sequence(id='sequence235', source_id='XP_002495560.1', sequence='MDNSDQEVQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR'), Sequence(id='sequence236', source_id='XP_003673548.1', sequence='MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS'), Sequence(id='sequence237', source_id='XP_003958955.1', sequence='MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLKTPRA'), Sequence(id='sequence238', source_id='XP_001644471.1', sequence='MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASASSSASSPSAST'), Sequence(id='sequence239', source_id='XP_003684279.1', sequence='MPYRENRNASSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence240', source_id='SMN18735.1', sequence='MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSSSISPPKSKGTTAS'), Sequence(id='sequence241', source_id='CAD1779387.1', sequence='MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTSSTSTSQVKAKETTAT'), Sequence(id='sequence242', source_id='KAG0666170.1', sequence='MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS'), Sequence(id='sequence243', source_id='XP_022464898.1', sequence='MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERTPVSSQQ'), Sequence(id='sequence244', source_id='XP_003669861.1', sequence='MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK'), Sequence(id='sequence245', source_id='XP_003678517.1', sequence='MASEHRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK'), Sequence(id='sequence246', source_id='KAG0659075.1', sequence='MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSSHGHTSNNNNNNNTPIQASPIAVRSSYNHRHH'), Sequence(id='sequence247', source_id='XP_451758.1', sequence='MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSPKRQVHTPPPSS'), Sequence(id='sequence248', source_id='NP_984991.1', sequence='MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPSEYTHHGRYRQPEHIRNMAEQ'), Sequence(id='sequence249', source_id='XP_017989070.1', sequence='MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVMAASSGYSPTSATVEQGQYRQSERAQHTASEQ'), Sequence(id='sequence250', source_id='KAG0673910.1', sequence='MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVHTPPPSS'), Sequence(id='sequence251', source_id='SMN21971.1', sequence='MNSEKNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL'), Sequence(id='sequence252', source_id='KAG0661436.1', sequence='MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN'), Sequence(id='sequence253', source_id='SCV02624.1', sequence='MSTNEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSRTPSPHRSP'), Sequence(id='sequence254', source_id='SCV99388.1', sequence='MSLATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS'), Sequence(id='sequence255', source_id='CUS20182.1', sequence='MSMVSGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS'), Sequence(id='sequence256', source_id='XP_045933944.1', sequence='MHFQQQQQQHYHTPLRHGSDPAQHITNNSEEHINNYGNNTVDTPQQLRHTSAMTVINSSQAATNNNYSDNNNNTSPVRGTTSTAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN'), Sequence(id='sequence257', source_id='KAA8901327.1', sequence='MSTPSSPSGGGSKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW'), Sequence(id='sequence258', source_id='KAF8417303.1', sequence='MSDSSTIASGSGAGGSYHHQQASTSSAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV'), Sequence(id='sequence259', source_id='KAF3929277.1', sequence='MTTTPPTKRETSPVSPLRASFANLNTEDHSQATAAIRAQAGHTRHESLEKYTRRDSTASENRNEEGYRERGSISSQSGAAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence260', source_id='OEJ86227.1', sequence='MTEYENGQQQQRERIRGQERESYDEQERESYDEQERERIREQERRINNEQQRRVNNEQQRRXNNQQRSTTNDNVSSNKNTHKDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH'), Sequence(id='sequence261', source_id='XP_046060918.1', sequence='MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS'), Sequence(id='sequence262', source_id='EPS36031.1', sequence='MTTTPPTKRDASPVSPLRASFANLNTDDHTSATAAIRAAAGHTRHESLEKYTRRDSTASENRPEEGYRERGSISSQGGSAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence263', source_id='KAI5807151.1', sequence='MHELPLAPSLPPPQSPPTPDRYSQGAARHYHSNSAASAPAMIGDAAGAYYRGSPPPPMPQQPYVPRDRSSESYHNGSSAQQQQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence264', source_id='XP_011117899.1', sequence='MTTTPPTKRESSPVSPLRASFANLNADDHSSATAAIRAAAGHTRHESLEKYTRRDSTASENRNDESYRDRSSVSSQGGSGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR'), Sequence(id='sequence265', source_id='KAI1438264.1', sequence='MEQDLHTTPGADLEPHGLPDDGSISSIEDTPEAASSLNGHETYHQHPQSLDYVVSSSQNTDETDPNAQYETVPATSQAQSISRPPSGLSGAGGDRQAAHSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence266', source_id='XP_022456167.1', sequence='MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV'), Sequence(id='sequence267', source_id='KAF3908940.1', sequence='MTTTPPTKRDVSPVSPLRASFANLNTTDDGQSATAAIRASAGHTRHESLEKYTRRDSTASESRNEDGYRERSSISSQGGSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR'), Sequence(id='sequence268', source_id='XP_006693239.1', sequence='MERDQLAAPAPSESAASDYRDHSLADAEVAPSSDCENNGFHDHHYSQSQHYDQDDAAESEPTARYNTPSGSGQQISRPPSGLSGERGAGYATDQGSRAGSNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV'), Sequence(id='sequence269', source_id='EWC45326.1', sequence='MATTPPTKRDTSPVSPLRASFANLNTTDDGQQSAAAAIRAAAGHTRHESLEKYTRRDSTASESRNDDGYRERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR'), Sequence(id='sequence270', source_id='KAF3930522.1', sequence='MTTTPPTKQGSRNVSPVSPLRASFANLNTTDENHSSATAAIRAAAGHTRHESLEKYTRRDSNASESKNEDGYRERSSVSSQGGSSQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR'), Sequence(id='sequence271', source_id='KAF8249497.1', sequence='MQQHDDDALPQPQTTELPLAPSLPPPVALAHSPPTPRRRNSSPTRHYHSSSNASGAPPYIGSPGSVESAQYYNSQGSPPTPAAPHQQQQFATSRADGGYHNGGGYAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence272', source_id='XP_002174495.1', sequence='MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV'), Sequence(id='sequence273', source_id='PRP83484.1', sequence='MGDQNDTEARIGHSRLPFFIMSGDGEYTGSGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS'), Sequence(id='sequence274', source_id='GAA97202.1', sequence='MASSTSTGAGSSSSRQRQESYRSSHSQQSSSQHAPAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI'), Sequence(id='sequence275', source_id='OBA26219.1', sequence='MESMLQSHNRRRHTNSMSISGSSNNNVHSELRQNNNNRISSMPSSQPASNSNNKPVDNIKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR'), Sequence(id='sequence276', source_id='KAI1823332.1', sequence='MEQDFHAVPAPDSEPHDHPDDGLGGLEESPDIAPGSNGHELYHQHPQSLDYVISNNQNIDDVDPNAPYEAVATTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence277', source_id='CDO57487.1', sequence='MSIPSIYPNHKPTGMYTGQFISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW'), Sequence(id='sequence278', source_id='KAI2629167.1', sequence='MDQDPMATPIPHDVHDDTLGGIEGSMHLPNEPHNHETHHRQSQSLDQGLANNAHPDEVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence279', source_id='KAI5811198.1', sequence='MSNDPLPTIPSATSSTVDLSNGNDGSAQNENEPPHRSQHHTGMTSIHLNDPTSQSNAAASYSQTHSGATMLSSGSGATGSFQQAGGPSSGGPAGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV'), Sequence(id='sequence280', source_id='KAG9017701.1', sequence='MSTAASGSGAPPATPLSAASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ'), Sequence(id='sequence281', source_id='OTA67948.1', sequence='MHFPGHLPDEPSSSSHEPHHRQSQSLDQGLANSAHPHPHPDDIDPNAQYEAQQYDPPQQSTQRPPSSMSSTGERQYTEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence282', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVPAAAAAQVPLPHSLSPPLQIDPHDDTLSSAGTVSHQALPDHNNFHEHNGYHDQPQHPIQFQPLDHSVNNSPRSYYPADQTDSEPTARYATPPVAAPAISRPSSGLSGQGAGYGADHVSRAGSNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence283', source_id='ORX96310.1', sequence='MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID'), Sequence(id='sequence284', source_id='XP_028477951.1', sequence='MTDPGYASSGSGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL'), Sequence(id='sequence285', source_id='XP_024666830.1', sequence='MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW'), Sequence(id='sequence286', source_id='KAI0099584.1', sequence='MHIPGHLPGESSSSHEPHHRQSQSLDQGLANSAPPLPDDIDPNAQYEAHQYDPPQQPVQRPASSMSSTGERQYNEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence287', source_id='KAI1801530.1', sequence='MHIAGEPGVHEPHHRQSRSLDQGLANSAHADDIDTHAVDPHAIDPIAVDHNAQYEAHSYEPPAQSMSRPASSSGTGERHLNGEASREGNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence288', source_id='KAF9351078.1', sequence='MSDTPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY'), Sequence(id='sequence289', source_id='KAF9160900.1', sequence='MAATSESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI'), Sequence(id='sequence290', source_id='KAG0263740.1', sequence='MAAAGDSGKKSSSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK'), Sequence(id='sequence291', source_id='KAI1135662.1', sequence='MEQDPVAAPVPHDIHEDTIGGIEGSMHIPAEPSTSHEPHRHRQSQSLDRGLASSKHPEDIDPNAQYDTPQYDPPQQSMPRPASSSSAGERHYAEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence292', source_id='XP_045969802.1', sequence='MTTTPPPLENNGSLPSHIDIDVAATPRQEHYTSSSDPSLAFSPQDSNSPSRANIGDDQRHSGTPPLSQSQLYGNGGGMNSFTSAAGAAAGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence293', source_id='KAI1414505.1', sequence='MHFSGEPSSSHEPLHRQSQSLDQGLANSAHPHPDDIDPNAQYEAHQYDPPQQSMQRPTSSMSSGGERHYTEQAPRESNGTDRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence294', source_id='KAG0239750.1', sequence='MATLGDSGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY'), Sequence(id='sequence295', source_id='XP_044688071.1', sequence='MTTTPPPPENNGSLPSHIDVDVAATPRQEHYTSSDPSLTFSPQDSNSPSRAIGDERNSGTPPLSQSQLYGNGGGMNNFTSAAAAAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence296', source_id='RPB01516.1', sequence='MTTTPPLLFSPSPPPPLPDSLYPDEPEEVTTPTATLPPPPPSPPPRQPSPARHQHSGSAPATVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGGGGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence297', source_id='KAG0236582.1', sequence='MAASADSARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS'), Sequence(id='sequence298', source_id='KAH6640987.1', sequence='MEQDQAISPAYAVAPDSALAPARIPSPAGFPTDPHDDTLSGVESVTHQAVPDHHIHEHNGFHEQQHISQLQPLDHNVTNSPRSPYPTDTTDSEPTARYATPPIQAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence299', source_id='XP_002493958.1', sequence='MPDSPRRNQHRRSHSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI'), Sequence(id='sequence300', source_id='KAA8914877.1', sequence='MTTTPPPSRTSTSDMDHSARTPSSSSSSIPEEYIHTELRLAPSLSSLQSPPTPDRGSPSRYHHSHSNSATSAPSDGASYYGGSPPAMRDRDREGYYGNGAGAAGGSGGGAGSSAYNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV'), Sequence(id='sequence301', source_id='XP_018701974.1', sequence='METDDVPAATLHDNLDDTLGGLDGSPQVPSSSHYSNHHHDHQYQNPHHSNNDTHEHEPQSPGGGPSHHQQQHHDEDPPCTRYTPPAPGSSAPASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence302', source_id='KAI2643608.1', sequence='MEHDLHGAPVSGLEPHAHHDDDSLNDADEHSDIASSLNGHESYHQPSQSLDYVLSHGQDTDEADPNSQYETQPTTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence303', source_id='KAG0125076.1', sequence='MTTTPPPLFSPSPPPPLPDSLCPDDPEEVTTPTSNLPPPPLPSPPPRQPSPVRHHHSGPAPAAVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGSGGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence304', source_id='KAH9904989.1', sequence='MEQDPVAAAVPQDGYDDTLGGIEGSPHVGPTQINREKRHQQSQSLDNGLPNNGHADEIDPNARYDTPPNPLQPHSISRPPSGLSGAGDRHNAYSDHASRGSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence305', source_id='VEU24358.1', sequence='MDNRSVSTRIPRSHSTSEALSEEPARSVSSTVDGYDNYYGHQHHHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV'), Sequence(id='sequence306', source_id='KAI1283572.1', sequence='MDTMEQDFHAAPIPGPHEHLDEPLPDTFADVEGGPHVSPSQNGHEVYHHHHQQSQSLDHGLASSQNHDEADLNGRYETPPSTAHPQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence307', source_id='KAI1500557.1', sequence='MMEHDPAFATAPGPHNGIDDMLGGIEGSPTLASGQNGHETYHHHHSQSFDQEIPLNENPDDMDTTAQYDTPPVTAQPQSISRPPSALDGAAGERHASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC'), Sequence(id='sequence308', source_id='KAI2623093.1', sequence='MDQDPITTPVQAPAQDPTPHELHEDTFGGIEGSMHLSGEPGTPEAHHRQSQSLDQGLANSVHPDEVDPNTQYEAHQYDAPPQSMPRPASSMSGAGERQYPEHASRESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence309', source_id='NP_593285.1', sequence='MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR'), Sequence(id='sequence310', source_id='KAI0431960.1', sequence='MDTMEQDFHAAPIPGPHEHLDETLPDTLADVEGAPHVSPSQNGHEVYHHHQQSHSLDQGLANSQTSDEPDLNGRYETPPSTGHAQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence311', source_id='KAH8926511.1', sequence='MSDSAGPLALEKGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV'), Sequence(id='sequence312', source_id='RMJ24013.1', sequence='MNPSYHNGYSSDSHAQYSTGPAGFNPPVHDSTSQDAEQTRLTFSPSITQQPQPPSLSRPSSAFSSGPERHGASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV'), Sequence(id='sequence313', source_id='KAF8931046.1', sequence='MAATGESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN'), Sequence(id='sequence314', source_id='ODQ76250.1', sequence='MSSAAPNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV'), Sequence(id='sequence315', source_id='KXJ93426.1', sequence='MDQEPAALPPTRNPLDVAPDDTLGGIESSPRVYSDPESTIRTHHHSQSLDQGLASSAHYQHNSEDMDHQTRQDTPPIPQQPQSISRPPSGLSGAGDRQPAQYSDHASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence316', source_id='XP_051368163.1', sequence='MDQDLLGTPTAPHDTLDDALAGVEGPLHLASESGNLEPHHRQSQSLDRGLANNAQVDDFDTAVPFDSPQYDTPPPAMQRPASSDSAAGEKQLAEHASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence317', source_id='GES63634.1', sequence='METIHNLNTGVSEPVEQQPQESAFEASPVSHPAGSTDEPTSASVYHRSGYNSDSHAQYSSLATHQPQPPTSSRPSSGLSGPERYGPSQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV'), Sequence(id='sequence318', source_id='RPA74746.1', sequence='MADHHEGSSHSYDRTSHSSRPATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV'), Sequence(id='sequence319', source_id='XP_024675402.1', sequence='MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPAGPYPSHVESVPPEVIPSASTYHAGYSSDSHANYSSNAVDFNSGSEYPPQPRAELPRAQEAVPSMMHPPAAPSSSRPSSGLSSGPDRLGSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL'), Sequence(id='sequence320', source_id='KAH6850716.1', sequence='MEQEQAFNPAYTMAPDPALAPAPIPAPISSPVGLPTDPHDDTLSGVESVTHQALPDHNIHDHNGFHEQQHLVQLQPLDHSVNNSPRSPYPTDTTDSEPTARYATPPIPAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence321', source_id='PHH71636.1', sequence='MEHQQPELDQQPPPLHAAHDSLDDTLGGIEGSPHVAAANNGFHQQSQSLDSAVPNSPRYDDDAANRHTPPVSSAPSLSRPGSQMSNPSSSNPPQQMHGNDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence322', source_id='KAJ3562589.1', sequence='MDTMEQDLHTTPIPGVHEHHHLDDALPDPHADVDARPHSAPGQNGHEVYHQQSHSLDQGIAHGQHPDEADLNGRYDTPPSATHPQSISRPPSGLSGAGGDRQTTYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV'), Sequence(id='sequence323', source_id='RDA84390.1', sequence='MDHQPAADQEQPQELPRPASHDGLDDTLGGIEGSPHPVASSNGFHAHQEAPGSPRYDDDNAARQTPPVSAPLSRPGSQMSNPPQHASGSDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence324', source_id='XP_007413704.1', sequence='MSNMTSSTGPAGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV'), Sequence(id='sequence325', source_id='KAI0376630.1', sequence='MHLPNEPHNHETHHRQSQSLDQGLANNVHPDDVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence326', source_id='XP_047831721.1', sequence='MEQDFHTAPIPGPREHLDALPDTHDTHADVVARPHTAPDQNGHEVYHQQSQSLDQGLSDSQHHDDADVAGRYETHPSTTHPQSISRPPSGLSGAGGDRQATYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence327', source_id='KAI9294962.1', sequence='MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE')], aligned_sequences=[Sequence(id='sequence328', source_id='BAH60832.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSA------------SE-----MR-----A---------ASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDN-ENKELV---------SQPHNYGHTSE---------------------------------'), Sequence(id='sequence329', source_id='CAI4663910.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------A-TPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQD--RKSHNIRKPSS-------------------SPSSKAPSPGVNT-----------------------'), Sequence(id='sequence330', source_id='EJT44931.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------T-TPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQD--RKNHTVKKPSS-------------------SPSSKPPSPGVNI-----------------------'), Sequence(id='sequence331', source_id='XP_037139093.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRP--SPSARTSFS--------------------------------------------------------'), Sequence(id='sequence332', source_id='XP_003680887.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRS--SPSTRSSTS--------------------------------------------------------'), Sequence(id='sequence333', source_id='XP_037144827.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MSQEYR----T---------RSRSRSF------------SD-----QA-----AT-----QEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIK--NSNTNVTTES-----------------------RRKSPTYTQ-----------------------'), Sequence(id='sequence334', source_id='AQZ18344.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG----------------------------------------------------------------------'), Sequence(id='sequence335', source_id='XP_002495560.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDN------------SD-----QE-------------VQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR-----------------------------------------------------------------------'), Sequence(id='sequence336', source_id='XP_003673548.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS----------------------------------------------------------------'), Sequence(id='sequence337', source_id='XP_003958955.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLK-TP-------RA---------------------------------------------------'), Sequence(id='sequence338', source_id='XP_001644471.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASAS--SSA-------S-------------------SPS-------AST-----------------------'), Sequence(id='sequence339', source_id='XP_003684279.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPY------------RE-----NR-----N---------A-SSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence340', source_id='SMN18735.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSS---SISPPKSKGTTAS--------------------------------------------'), Sequence(id='sequence341', source_id='CAD1779387.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTS---STSTSQVKAKETTAT------------------------------------------'), Sequence(id='sequence342', source_id='KAG0666170.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS-------------------------------------------'), Sequence(id='sequence343', source_id='XP_022464898.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERT-PVSSQQ-----------------------------------------------------'), Sequence(id='sequence344', source_id='XP_003669861.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK---------------------------------------------------------------------------'), Sequence(id='sequence345', source_id='XP_003678517.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------------------------SE----------------------HRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK----------------------------------------------------------------------'), Sequence(id='sequence346', source_id='KAG0659075.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSS--------HG--HTSNNNNNNNTPIQASPIAVRSSYNHR----HH-------------'), Sequence(id='sequence347', source_id='XP_451758.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSP-KRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence348', source_id='NP_984991.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPS--------------------E------YTHHGRYRQ--------PEHIRNMAE----------Q--------'), Sequence(id='sequence349', source_id='XP_017989070.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVM-----AASSGYSPTSA------TVEQGQYRQ--------SERAQHTAS----------EQ-------'), Sequence(id='sequence350', source_id='KAG0673910.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence351', source_id='SMN21971.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSE----KNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL-------------------------------------------------------------------------'), Sequence(id='sequence352', source_id='KAG0661436.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN--------------------------------------------------------------------------'), Sequence(id='sequence353', source_id='SCV02624.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MST----NEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSR-TPSPHRSP------------------------------------------------------'), Sequence(id='sequence354', source_id='SCV99388.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSL----ATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS-----------------------------------------------------------------------'), Sequence(id='sequence355', source_id='CUS20182.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----SMV----SGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS----------------------------------------------------------------'), Sequence(id='sequence356', source_id='XP_045933944.1', sequence='-------------------------------------MHFQQ----------------------------------------------------------------------QQQQHYHTPLRHGSDPAQ-HITNNSEEHINN--------YGNNTVDTPQQLRHTS---------AMTVINS---SQAATNNNYSDN---NNNT-SPVRG-----TTS----TAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN--------------------------------------------------------------------------'), Sequence(id='sequence357', source_id='KAA8901327.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPS-----S------PSG-----------GG---------------------------SKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence358', source_id='KAF8417303.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-SSTIA-------------SGSGAGGSYHHQQA------STS-------------SAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence359', source_id='KAF3929277.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RETSP----VSPLRASF--ANLN--------TEDHS---------QATAAIR---AQ---------------AGHTR-HESL--EKYTRR-DSTASE-NRNEEGY----------------------RERGSISSQSGAAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence360', source_id='OEJ86227.1', sequence='------------------------------------MTEYEN----------------------------------------------G----QQQQ---------RERIRGQERESYDEQERESYDEQERERIREQERRINN--------EQQRRVNNEQQ--------------------------RRXNNQQRST---TNDN-VSSNK-----NTH----KDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH-------------------------------------------------------------------------'), Sequence(id='sequence361', source_id='XP_046060918.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS-----------------------------------------------------------------'), Sequence(id='sequence362', source_id='EPS36031.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDASP----VSPLRASF--ANLN--------TDDHT---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRPEEGY----------------------RERGSISSQGGSAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence363', source_id='KAI5807151.1', sequence='--------------------------------------------------------------------------MHELPLAPSLPPPQ----SPPTPDR----------YSQGAARHY---HSNSAAS-A-----PAMIG-----------DA-------AGAYYRGSPPPPMPQQPYVP-R----D-RS-SESYHNGSS--------------------AQQ-QQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence364', source_id='XP_011117899.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RESSP----VSPLRASF--ANLN--------ADDHS---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRNDESY----------------------RDRSSVSSQG-GSG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR----------------------------------------------------------------------------'), Sequence(id='sequence365', source_id='KAI1438264.1', sequence='---------------------------------------MEQDLHTTPGADLE----------P--HGLPDD---GSI---------SSIEDTPEA--------AS--SLNGHETYHQ---HPQSLDYVV-----SSS---------------QNTDETDPNAQYET-VPATSQAQSISR-PPSGLSGAGGDRQAA------------------------HSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence366', source_id='XP_022456167.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV---------------------------------------------------------------------------------'), Sequence(id='sequence367', source_id='KAF3908940.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDVSP----VSPLRASF--ANLN--------TTDDGQS--------ATAAIR---AS---------------AGHTR-HESL--EKYTRR-DSTASE-SRNEDGY----------------------RERSSISSQG-GSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence368', source_id='XP_006693239.1', sequence='---------------------------------------MERDQLAAPAPSE------------------S-----AA---------SDYRDHSLADAEVAPSSDCE--NNGFHDHHY--SQSQHYDQ-------DDAAESE---PT---------------ARYNT-PSGS--GQQISR-PPSGLS-GERGAGYATDQGSRAG------------SNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV---------------------------------------------------------------------------------'), Sequence(id='sequence369', source_id='EWC45326.1', sequence='---------------------------------------MATTPP-------------------------------TK------------RDTSP----VSPLRASF--ANLN--------TTDDGQQ-------SAAAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-SRNDDGY----------------------RERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR----------------------------------------------------------------------------'), Sequence(id='sequence370', source_id='KAF3930522.1', sequence='---------------------------------------MTTTPP-------------------------------TK---------QGSRNVSP----VSPLRASF--ANLN--------TTDENHS-------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSNASE-SKNEDGY----------------------RERSSVSSQGGS--SQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR----------------------------------------------------------------------------'), Sequence(id='sequence371', source_id='KAF8249497.1', sequence='-----------------------------------------------------MQ------Q-HDDDALPQP-QTTELPLAPSLPPPVALAHSPPTPRR----------RNSSPTRHY---HSSSNASGA-----PPYIG-----------SP---GSVESAQYYNSQGSPPTPAAPHQQ-QQFATS-RA-DGGYHNGGG-------------------------YAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence372', source_id='XP_002174495.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence373', source_id='PRP83484.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------MG-----------DQ---NDTE-------------ARIGHSR-LPFFIM-SG-DGEYTG-----------------------------SGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS--------------------------------------------------------------------------------'), Sequence(id='sequence374', source_id='GAA97202.1', sequence='-------------------------------------------------------------------------------------------------------------------------MASSTSTG---------AG-----------SS---SSRQRQESYRSS--------------------------HSQQSS--------------------SQH-APAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI---------------------------------------------------------------------------------'), Sequence(id='sequence375', source_id='OBA26219.1', sequence='------------------------------------MESML-------------------------------------------------------------------------------------QSHNRRR-HTNSMSISG--------SSNNNVHSELRQNNNN---------RISSMPS---SQPASN----------SNN-KPVDN-----IKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR------------------------------------------------------------------------'), Sequence(id='sequence376', source_id='KAI1823332.1', sequence='---------------------------------------MEQDFHAVPAPDSE----------P--HDHPDD---G-L---------GGLEESPDI--------AP--GSNGHELYHQ---HPQSLDYVI-----SNN---------------QNIDDVDPNAPYEA-VATTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence377', source_id='CDO57487.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPS-----IYPNH-KPTGM--------YTGQ-----------------------FISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence378', source_id='KAI2629167.1', sequence='---------------------------------------MDQD--------PM----------A--TPIPHDVHDDTL---------GGIEGSMHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNA---------------HPDEVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence379', source_id='KAI5811198.1', sequence='---------------------------------------MSNDPL----PTIP----------SA-TSSTVD----LS---------NG--NDGSA---QNE---N---EPPHRSQHH--TGM------------TSIHL-----NDPTSQSNAA---ASYSQTHSG-ATMLS-------------SGSGATGSFQQAGG------PSSGGP-----AGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence380', source_id='KAG9017701.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAASGSGAPPAT--------------------PLS-AASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ---------------------------------------------------------------------------------'), Sequence(id='sequence381', source_id='OTA67948.1', sequence='-----------------------------------------------------------------------------------------MHFPGHLP---------DEPSSSSHEPHH--RQSQSLDQGL-----ANSAHP-----------HPHPDDIDPNAQYEA-QQYDPPQQSTQR-PPSSMSS-TGERQY---------------------TEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence382', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVP---A-----------AAAAQVPLPH----------SLSPPLQIDPHDDTL---------SSAGTVSHQ---ALPDHNNFHEHNGYHD------QPQHPIQFQ-----PLDHSVN---NSPRSYYPADQTDSEPTARYAT-PPVA--APAISR-PSSGLSGQGAGYGAD--HVSRAG-----------------SNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence383', source_id='ORX96310.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID---------------------------------------------------------------------------------'), Sequence(id='sequence384', source_id='XP_028477951.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTD-P--------------------------------GYASSG-SGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL---------------------------------------------------------------------------------'), Sequence(id='sequence385', source_id='XP_024666830.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence386', source_id='KAI0099584.1', sequence='-----------------------------------------------------------------------------------------MHIPGHLP---------GES-SSSHEPHH--RQSQSLDQGL-----ANSAP-------------PLPDDIDPNAQYEA-HQYDPPQQPVQR-PASSMSS-TGERQY---------------------NEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence387', source_id='KAI1801530.1', sequence='---------------------------------------------------------------------------------------------MHIA---------GEPGV--HEPHH--RQSRSLDQGL-----ANSAHADDIDTHAVDPHAIDPIAVDHNAQYEA-HSYEPPAQSMSR-PASS--SGTGERHL---------------------NGE--ASREGNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence388', source_id='KAF9351078.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-------------------------TPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence389', source_id='KAF9160900.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATS-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI-----------------------------------------------------------------------'), Sequence(id='sequence390', source_id='KAG0263740.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAGD-------------------------SGKKS--SSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK---------------------------------------------------------------------------------'), Sequence(id='sequence391', source_id='KAI1135662.1', sequence='-----------------------------------------------MEQDPV----------A--APVPHDIHEDTI---------GGIEGSMHIP---------AEPSTSHEPHRH--RQSQSLDRGL-----ASSK---------------HPEDIDPNAQYDT-PQYDPPQQSMPR-PASS-SS-AGERHY---------------------AEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence392', source_id='XP_045969802.1', sequence='---------------------------------------MTTTPP----PLEN----------NGSLPSHID----ID---------VA---------------------ATPRQEHY--TSSSD----------PSLAFSP---QDSNSPSRAN---IGDDQRHSG-TPPLSQSQLY--------GNGGGMNSFTSAAG------AA----------------AGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence393', source_id='KAI1414505.1', sequence='-----------------------------------------------------------------------------------------MHFSGE--------------PSSSHEPLH--RQSQSLDQGL-----ANSAHP-------------HPDDIDPNAQYEA-HQYDPPQQSMQR-PTSSMSS-GGERHY---------------------TEQ--APRESNGT-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence394', source_id='KAG0239750.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATLGD-------------------------SGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence395', source_id='XP_044688071.1', sequence='---------------------------------------MTTTPP----PPEN----------NGSLPSHID----VD---------VA---------------------ATPRQEHY--TS-SD----------PSLTFSP---QDSNSPSRAI-----GDERNSG-TPPLSQSQLY--------GNGGGMNNFTSAAA------------------------AAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence396', source_id='RPB01516.1', sequence='---------------------------------------MTTTPPLLFSPSP-------PPP-LPDSLYPDEPEEVTTPTA-TLPPPP------PSPPP----------RQPSPARHQ---HSGSAPA---------TVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGG-----------------------------GGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence397', source_id='KAG0236582.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-----------------------------SADS--ARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS----------------------------------------------------------------------------------'), Sequence(id='sequence398', source_id='KAH6640987.1', sequence='MEQD-QAIS------PAYAVAPDSALA------------------PARIP--------------SPAGFPTDPHDDTL---------SGVESVTHQ---AVPDHH-IHEHNGFHE------Q-QHISQLQ-----PLDHNVT---NSPRSPYPTDTTDSEPTARYAT-PPIQ--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence399', source_id='XP_002493958.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSPR-------------------RNQHRRS----------------------HSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI---------------------------------------------------------------------------------'), Sequence(id='sequence400', source_id='KAA8914877.1', sequence='---------------------------------------MTTTPPPSRTSTSDMDHSARTPS-SSSSSIPEEYIHTELRLAPS----LSSLQSPPTPDR----------GSPSRYHHS---HSNSATSAP----------------------------SDGASYYGGSPPA-MRDRD-RE-GYYGNGAGA-AGGSGGGAG--------------------SSA-YNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence401', source_id='XP_018701974.1', sequence='---------------------------------------METDDV--PAATLH----------D-----NLD----DT---------LG----GLDGSPQVPSSSHY--SNHHHDHQY--QNPHHSNN-------DTHEHEP---QSPG-GGPSH---HQ-QQHHDE-DPPC--TRY-TP-PAPGSS-APASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence402', source_id='KAI2643608.1', sequence='---------------------------------------MEHDLHGAPVSGLE----------P--HAHHDD---DSL---------NDADEHSDI--------AS--SLNGHESYHQ---PSQSLDYVL-----SHG---------------QDTDEADPNSQYET-QPTTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence403', source_id='KAG0125076.1', sequence='---------------------------------------MTTTPPPLFSPSP-------PPP-LPDSLCPDDPEEVTTPTS-NLPPPP-----LPSPPP----------RQPSPVRHH---HSGPAPA---------AVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGS-----------------------------GGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence404', source_id='KAH9904989.1', sequence='---------------------------------------MEQDPV--------------------AAAVPQDGYDDTLG---------GIEGSPHVGPT----------QINREKRHQ---QSQSLDNGL-----P-NNG-----------HA---DEIDPNARYDTPPN-PLQPHSISR-PPSGLS-GAGDRHNAYSDH--------------------ASR-GSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence405', source_id='VEU24358.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------MDNRSVSTRIPRSHSTSEALSEEPARSVSSTV--DGYDNYY-----------GHQH---HHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence406', source_id='KAI1283572.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--EPLPDTF---------ADVEGGPHV--------SP--SQNGHEVYHHHHQQSQSLDHGL-----ASS---------------QNHDEADLNGRYET-PPSTAHPQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence407', source_id='KAI1500557.1', sequence='--------------------------------------MMEHDPAFATAPGPH----------N-----GIDD--------------------MLGGIEGSPTLASG--QNGHETYHH--HHSQSFDQ-------E----IP---LN---ENPDD---MDTTAQYDT-PPVTAQPQSISR-PPSALD-GAAGER-----------------------HASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence408', source_id='KAI2623093.1', sequence='---------------------------------------MDQDPITTPVQAPA----------Q--DPTPHELHEDTF---------GGIEGSMHLS---------GEPGT--PEAHH--RQSQSLDQGL-----ANSV---------------HPDEVDPNTQYEA-HQYDAPPQSMPR-PASSMSG-AGERQY---------------------PEH--ASRESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence409', source_id='NP_593285.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR---------------------------------------------------------------------------------'), Sequence(id='sequence410', source_id='KAI0431960.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--ETLPDTL---------ADVEGAPHV--------SP--SQNGHEVYHHH-QQSHSLDQGL-----ANS---------------QTSDEPDLNGRYET-PPSTGHAQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence411', source_id='KAH8926511.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSAGP-----LALE-----KGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV---------------------------------------------------------------------------------'), Sequence(id='sequence412', source_id='RMJ24013.1', sequence='-----------------------------------------MNPS-------------------------------YH---------NGYSSDSHA--QYSTGPAGF--NPPVHDS-----TSQDAEQ-------TRLTFSP---SI---------------TQQPQ-PPSL---SRPS---SAFSS-GPERHG-------------------------ASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV---------------------------------------------------------------------------------'), Sequence(id='sequence413', source_id='KAF8931046.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATG-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN---------------------------------------------------------------------------------'), Sequence(id='sequence414', source_id='ODQ76250.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS------AA----------------PNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV---------------------------------------------------------------------------------'), Sequence(id='sequence415', source_id='KXJ93426.1', sequence='---------------------------------------MDQEPAAL------------PPTRNPLDVAPDD----TL---------GGIESSPRVYSD----------PESTIRTHH---HSQSLDQGL-----ASSAH-----------YQHNSEDMD-HQTRQDTPPIPQQPQSISR-PPSGLSGAGDRQPAQYSDH--------------------ASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence416', source_id='XP_051368163.1', sequence='---------------------------------------MDQDLLG-----------------T--PTAPHDTLDDAL---------AGVEGPLHLA---------SESGN--LEPHH--RQSQSLDRGL-----ANNAQVDDF---------------DTAVPFDS-PQYDTPPPAMQR-PASSD-SAAGEKQL---------------------AEH--ASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence417', source_id='GES63634.1', sequence='-------METIHNL--NTGV-SEPVEQQP------QESAFEASPVSHPAGSTD----------E-----PTSASVYHR---------SGYNSDSHA--QYSSLA----------------------------------------------------------THQPQ-PP------TSSR-PSSGLS-GPERYGP----------------------SQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV---------------------------------------------------------------------------------'), Sequence(id='sequence418', source_id='RPA74746.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------M---------------ADHHE-GSSH---SYDR---TSHSS-RP-------------------------------ATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence419', source_id='XP_024675402.1', sequence='-------MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPA-GPYPSHV----------ESVPPEVIPSASTYH---------AGYSSDSHAN--YSSNAVDF--NS--------------------------GSEYP---PQPRAELPRA---QEAVPSMMH-PPAA---PSSSR-PSSGLSSGPDRL-----------------------GSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL---------------------------------------------------------------------------------'), Sequence(id='sequence420', source_id='KAH6850716.1', sequence='MEQE-QAFN------PAYTMAPDPALA------------------PAPIPAPI----------SSPVGLPTDPHDDTL---------SGVESVTHQ---ALPDHN-IHDHNGFHE------Q-QHLVQLQ-----PLDHSVN---NSPRSPYPTDTTDSEPTARYAT-PPIP--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence421', source_id='PHH71636.1', sequence='---------------------------------------MEHQQPE-LDQ--Q----------PPPLHAAHDSLDDTL---------GGIEGSPHVAA----------ANNGFHQ------QSQSLDSAV-----P---------NSPR--------YDDDAANRHT-P-PVSSAPSLSR-PGSQMS-----------------NPSSSNPPQQMHG----NDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence422', source_id='KAJ3562589.1', sequence='------------------------------------MDTMEQDLHTTPIPGVH----------E--HHHLDDALPDPH---------ADVDARPHS--------AP--GQNGHEVYH---QQSHSLDQGI-----AHG---------------QHPDEADLNGRYDT-PPSATHPQSISR-PPSGLSGAGGDRQTT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV--------------------------------------------------------------------------------'), Sequence(id='sequence423', source_id='RDA84390.1', sequence='---------------------------------------MDHQPAA-DQEQPQ----------ELPRPASHDGLDDTL---------GGIEGSPHPVA----------SSNGFHA------HQ-----EA-----P---------GSPR--------YDDDNAARQT-P-PVSA--PLSR-PGSQMS-----------------N-----PPQHASG----SDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence424', source_id='XP_007413704.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNMTSSTGP-----AGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV---------------------------------------------------------------------------------'), Sequence(id='sequence425', source_id='KAI0376630.1', sequence='---------------------------------------------------------------------------------------------MHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNV---------------HPDDVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence426', source_id='XP_047831721.1', sequence='---------------------------------------MEQDFHTAPIPGPR----------E--HLDALPDTHDTH---------ADVVARPHT--------AP--DQNGHEVYH---QQSQSLDQGL-----SDS---------------QHHDDADVAGRYET-HPSTTHPQSISR-PPSGLSGAGGDRQAT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence427', source_id='KAI9294962.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE-------------------------------------------------------------------------------')], standard_numberings=[StandardNumbering(id='standardnumbering201', reference_id='BAH60832.1', numbered_id='CAI4663910.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', 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'0.167', '0.168', '0.169', '0.170', '0.171', '0.172', '0.173', '0.174', '0.175', '0.176', '0.177', '0.178', '0.179', '0.180', '1', '2.181', '3.182', '3.183', '3.184', '3.185', '3.186', '3.187', '3.188', '3.189', '3.190', '3.191', '3.192', '3.193', '3.194', '4.195', '5', '5.196', '5.197', '5.198', '5.199', '5.200', '6', '7', '7.201', '7.202', '7.203', '7.204', '7.205', '8', '8.206', '8.207', '8.208', '8.209', '8.210', '8.211', '8.212', '8.213', '8.214', '9', '10.215', '11.216', '12.217', '13.218', '14.219', '15.220', '16.221', '17.222', '18.223', '19.224', '20.225', '21.226', '22.227', '23.228', '24.229', '25.230', '26.231', '27.232', '28.233', '29.234', '30.235', '31.236', '32.237', '33.238', '34.239', '35.240', '36.241', '37.242', '38.243', '39.244', '40.245', '41.246', '42.247', '43.248', '44.249', '45.250', '46.251', '47.252', '48.253', '49.254', '50.255', '51.256', '52.257', '53.258', '54.259', '55.260', '56.261', '57.262', '58.263', '59.264', '60.265', '61.266', '62.267', '63.268', '64.269', '65.270', '66.271', '67.272', '68.273', '69.274', '70.275', '71.276', '72.277', '73.278', '74.279', '75.280', '76.281', '77.282', '78.283', '79.284', '80.285', '81.286', '82.287', '83.288', '84.289', '85.290', '86.291', '87.292', '88.293', '89.294', '90.295', '91.296', '92.297', '93.298', '94.299', '95.300', '96.301', '97.302', '98.303', '99.304', '100.305', '101.306', '102.307', '103.308', '104.309', '105.310', '106.311', '107.312', '108.313', '109.314', '110.315', '111.316', '112.317', '113.318', '114.319', '115.320', '116.321', '117.322', '118.323', '119.324', '120.325', '121.326', '122.327', '123.328', '124.329', '125.330', '126.331', '127.332', '128.333', '129.334', '130.335', '131.336', '132.337', '133.338', '134.339', '135.340', '136.341', '137.342', '138.343', '139.344', '140.345', '141.346', '142.347', '143.348', '144.349', '145.350', '146.351', '147.352', '148.353', '149.354', '150.355', '151.356', '152.357', '153.358', '154.359', '155.360', '156.361', '157.362', '158.363', '159.364', '160.365', '161.366', '162.367', '163.368', '164.369', '165.370', '166.371', '167.372', '168.373', '169.374', '170.375', '171.376', '172.377', '173.378', '174.379', '175.380', '176.381', '177.382', '178.383', '179.384', '180.385', '181.386', '182.387', '183.388', '184.389', '185.390', '186.391', '187.392', '188.393', '189.394', '190.395', '191.396', '192.397', '193.398', '194.399', '195.400', '196.401', '197.402', '198.403', '199.404', '200.405', '201.406', '202.407', '203.408', '204.409', '205.410', '206.411', '207.412', '208.413', '209.414', '210.415', '211.416', '212.417', '213.418', '214.419', '215.420', '216.421', '217', '218', '219', '220', '221', '222', '223', '224', '225', '226', '227', '228', '229', '230', '231', '232', '233', '234', '235', '236', '237', '237.422', '238', '239', '240', '241', '242', '243', '243.423', '243.424', '243.425', '243.426', '243.427', '243.428', '243.429', '243.430', '243.431', '244', '245', '246', '247', '248', '249', '250', '251', '252', '253', '254', '254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454', '254.455', '254.456', '254.457', '254.458', '254.459', '254.460', '254.461', '254.462', '254.463', '254.464']), StandardNumbering(id='standardnumbering299', reference_id='BAH60832.1', numbered_id='KAI9294962.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', '0.45', '0.46', '0.47', '0.48', '0.49', '0.50', '0.51', '0.52', '0.53', '0.54', '0.55', '0.56', '0.57', '0.58', '0.59', '0.60', '0.61', '0.62', '0.63', '0.64', '0.65', '0.66', '0.67', '0.68', '0.69', '0.70', '0.71', '0.72', '0.73', '0.74', '0.75', '0.76', '0.77', '0.78', '0.79', '0.80', '0.81', '0.82', '0.83', '0.84', '0.85', '0.86', '0.87', '0.88', '0.89', '0.90', '0.91', '0.92', '0.93', '0.94', '0.95', '0.96', '0.97', '0.98', '0.99', '0.100', '0.101', '0.102', '0.103', '0.104', '0.105', '0.106', '0.107', '0.108', '0.109', '0.110', '0.111', '0.112', '0.113', '0.114', '0.115', '0.116', '0.117', '0.118', '0.119', '0.120', '0.121', '0.122', '0.123', '0.124', '0.125', '0.126', '0.127', '0.128', '0.129', '0.130', '0.131', '0.132', '0.133', '0.134', '0.135', '0.136', '0.137', '0.138', '0.139', '0.140', '0.141', '0.142', '0.143', '0.144', '0.145', '0.146', '0.147', '0.148', '0.149', '0.150', '0.151', '0.152', '0.153', '0.154', '0.155', '0.156', '0.157', '0.158', '0.159', '0.160', '0.161', '0.162', '0.163', '0.164', '0.165', '0.166', '0.167', '0.168', '0.169', '0.170', '0.171', '0.172', '0.173', '0.174', '0.175', '0.176', '0.177', '0.178', '0.179', '0.180', '1', '2', '3', '3.181', '3.182', '3.183', '3.184', '3.185', '3.186', '3.187', '3.188', '3.189', '3.190', '3.191', '3.192', '4', '5', '5.193', '5.194', '5.195', '5.196', '5.197', '6', '7', '7.198', '7.199', '7.200', '7.201', '7.202', '8', '8.203', '8.204', '8.205', '8.206', '8.207', '8.208', '8.209', '8.210', '8.211', '9', '10', '11', '12', '13', '14', '15', '16', '17', '18', '19.212', '20.213', '21.214', '22.215', '23.216', '24.217', '25.218', '26.219', '27.220', '28.221', '29.222', '30.223', '31.224', '32.225', '33.226', '34.227', '35.228', '36.229', '37.230', '38.231', '39.232', '40.233', '41.234', '42.235', '43.236', '44.237', '45.238', '46.239', '47.240', '48.241', '49.242', '50.243', '51.244', '52.245', '53.246', '54.247', '55.248', '56.249', '57.250', '58.251', '59.252', '60.253', '61.254', '62.255', '63.256', '64.257', '65.258', '66.259', '67.260', '68.261', '69.262', '70.263', '71.264', '72.265', '73.266', '74.267', '75.268', '76.269', '77.270', '78.271', '79.272', '80.273', '81.274', '82.275', '83.276', '84.277', '85.278', '86.279', '87.280', '88.281', '89.282', '90.283', '91.284', '92.285', '93.286', '94.287', '95.288', '96.289', '97.290', '98.291', '99.292', '100.293', '101.294', '102.295', '103.296', '104.297', '105.298', '106.299', '107.300', '108.301', '109.302', '110.303', '111.304', '112.305', '113.306', '114.307', '115.308', '116.309', '117.310', '118.311', '119.312', '120.313', '121.314', '122.315', '123.316', '124.317', '125.318', '126.319', '127.320', '128.321', '129.322', '130.323', '131.324', '132.325', '133.326', '134.327', '135.328', '136.329', '137.330', '138.331', '139.332', '140.333', '141.334', '142.335', '143.336', '144.337', '145.338', '146.339', '147.340', '148.341', '149.342', '150.343', '151.344', '152.345', '153.346', '154.347', '155.348', '156.349', '157.350', '158.351', '159.352', '160.353', '161.354', '162.355', '163.356', '164.357', '165.358', '166.359', '167.360', '168.361', '169.362', '170.363', '171.364', '172.365', '173.366', '174.367', '175.368', '176.369', '177.370', '178.371', '179.372', '180.373', '181.374', '182.375', '183.376', '184.377', '185.378', '186.379', '187.380', '188.381', '189.382', '190.383', '191.384', '192.385', '193.386', '194.387', '195.388', '196.389', '197.390', '198.391', '199.392', '200.393', '201.394', '202.395', '203.396', '204.397', '205.398', '206.399', '207.400', '208.401', '209.402', '210.403', '211.404', '212.405', '213.406', '214.407', '215.408', '216.409', '217.410', '218.411', '219', '220', '221', '222', '223', '224', '225', '226', '227', '228', '229', '230', '231', '232', '233', '234', '235', '236', '237', '237.412', '238', '239', '240', '241', '242', '243', '243.413', '243.414', '243.415', '243.416', '243.417', '243.418', '243.419', '243.420', '243.421', '244', '245', '246', '247', '248', '249', '250', '251', '252', '253', '254', '254.422', '254.423', '254.424', '254.425', '254.426', '254.427', '254.428', '254.429', '254.430', '254.431', '254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454'])])"
+ ]
+ },
+ "execution_count": 14,
+ "metadata": {},
+ "output_type": "execute_result"
}
],
"source": [
- "print(alignment)"
+ "alignment"
]
},
{
"cell_type": "code",
- "execution_count": 9,
+ "execution_count": 7,
"metadata": {},
"outputs": [
{
"name": "stderr",
"output_type": "stream",
"text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 2/2 [00:00<00:00, 1000.55it/s]\n"
+ "⬇️ Fetching protein sequences: 100%|██████████| 2/2 [00:00<00:00, 660.05it/s]\n"
]
}
],
@@ -260,40 +186,126 @@
},
{
"cell_type": "code",
- "execution_count": 11,
+ "execution_count": 18,
"metadata": {},
"outputs": [
{
"name": "stderr",
"output_type": "stream",
"text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 38.26it/s]\n"
- ]
- },
- {
- "ename": "UnboundLocalError",
- "evalue": "local variable 'alignment_result' referenced before assignment",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mUnboundLocalError\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[11], line 8\u001b[0m\n\u001b[1;32m 5\u001b[0m sequences \u001b[38;5;241m=\u001b[39m ProteinInfo\u001b[38;5;241m.\u001b[39mfrom_ncbi(ncbi_accessions)\n\u001b[1;32m 7\u001b[0m \u001b[38;5;66;03m# Create and run alignment\u001b[39;00m\n\u001b[0;32m----> 8\u001b[0m alignment \u001b[38;5;241m=\u001b[39m \u001b[43mAlignment\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43mfrom_sequences\u001b[49m\u001b[43m(\u001b[49m\u001b[43msequences\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43maligner\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mPairwiseAligner\u001b[49m\u001b[43m)\u001b[49m\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:247\u001b[0m, in \u001b[0;36mAlignment.from_sequences\u001b[0;34m(cls, sequences, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 242\u001b[0m alignment \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mcls\u001b[39m(\n\u001b[1;32m 243\u001b[0m input_sequences\u001b[38;5;241m=\u001b[39msequences,\n\u001b[1;32m 244\u001b[0m )\n\u001b[1;32m 246\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m aligner \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;129;01mnot\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m:\n\u001b[0;32m--> 247\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[43malignment\u001b[49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43malign\u001b[49m\u001b[43m(\u001b[49m\u001b[43maligner\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 249\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m alignment\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:144\u001b[0m, in \u001b[0;36mAlignment.align\u001b[0;34m(self, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 141\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_container_align(aligner, \u001b[38;5;241m*\u001b[39m\u001b[38;5;241m*\u001b[39mkwargs)\n\u001b[1;32m 143\u001b[0m \u001b[38;5;28;01melif\u001b[39;00m \u001b[38;5;28missubclass\u001b[39m(aligner, PairwiseAligner):\n\u001b[0;32m--> 144\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28;43mself\u001b[39;49m\u001b[38;5;241;43m.\u001b[39;49m\u001b[43m_python_align\u001b[49m\u001b[43m(\u001b[49m\u001b[43maligner\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[38;5;241;43m*\u001b[39;49m\u001b[43mkwargs\u001b[49m\u001b[43m)\u001b[49m\n\u001b[1;32m 146\u001b[0m \u001b[38;5;28;01melse\u001b[39;00m:\n\u001b[1;32m 147\u001b[0m \u001b[38;5;28;01mraise\u001b[39;00m \u001b[38;5;167;01mValueError\u001b[39;00m(\n\u001b[1;32m 148\u001b[0m \u001b[38;5;124m\"\u001b[39m\u001b[38;5;124maligner must be an instance of AbstractContainer or PairwiseAligner\u001b[39m\u001b[38;5;124m\"\u001b[39m\n\u001b[1;32m 149\u001b[0m )\n",
- "File \u001b[0;32m~/Documents/GitHub/pyeed/pyeed/core/alignment.py:191\u001b[0m, in \u001b[0;36mAlignment._python_align\u001b[0;34m(self, aligner, **kwargs)\u001b[0m\n\u001b[1;32m 188\u001b[0m alignment_result \u001b[38;5;241m=\u001b[39m pairwise_aligner\u001b[38;5;241m.\u001b[39malign()\n\u001b[1;32m 189\u001b[0m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39mmethod \u001b[38;5;241m=\u001b[39m pairwise_aligner\u001b[38;5;241m.\u001b[39mmode\n\u001b[0;32m--> 191\u001b[0m \u001b[38;5;28;01mreturn\u001b[39;00m \u001b[38;5;28mself\u001b[39m\u001b[38;5;241m.\u001b[39m_map_pairwise_alignment_results(\u001b[43malignment_result\u001b[49m)\n",
- "\u001b[0;31mUnboundLocalError\u001b[0m: local variable 'alignment_result' referenced before assignment"
+ "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 40.43it/s]\n",
+ "⛓️ Running pairwise alignments: 100%|██████████| 4950/4950 [00:00<00:00, 17443.83it/s]\n"
]
}
],
"source": [
+ "%reload_ext autoreload\n",
+ "%autoreload 2\n",
+ "from pyeed.core import ProteinInfo, Alignment\n",
"from pyeed.aligners import PairwiseAligner\n",
+ "from pyeed.network.network import SequenceNetwork\n",
"\n",
"\n",
"ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\", \"AAT46414.1\", \"AAT46415.1\"]\n",
"sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
"\n",
"# Create and run alignment\n",
- "alignment = Alignment.from_sequences(sequences, aligner=PairwiseAligner)"
+ "alignments = Alignment.from_sequences(blast_results, aligner=PairwiseAligner)"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 9,
+ "metadata": {},
+ "outputs": [],
+ "source": [
+ "n = SequenceNetwork(\n",
+ " sequences=sequences,\n",
+ " pairwise_alignments=alignments,\n",
+ " threshold=0.5,\n",
+ " weight=\"identity\",\n",
+ " color=\"organism\",\n",
+ " label=\"organism\",\n",
+ ")"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 10,
+ "metadata": {},
+ "outputs": [
+ {
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "pairwisealignment1\n",
+ "pairwisealignment2\n",
+ "pairwisealignment3\n",
+ "pairwisealignment4\n",
+ "pairwisealignment5\n",
+ "pairwisealignment6\n"
+ ]
+ },
+ {
+ "data": {
+ "text/plain": [
+ "EdgeView([('QGC48744.1', 'AAT46413.1'), ('QGC48744.1', 'AAT46414.1'), ('AAT46413.1', 'AAT46414.1')])"
+ ]
+ },
+ "execution_count": 10,
+ "metadata": {},
+ "output_type": "execute_result"
+ }
+ ],
+ "source": [
+ "n.graph().edges()"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 11,
+ "metadata": {},
+ "outputs": [
+ {
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "QGC48744.1 AAT46413.1\n",
+ "QGC48744.1 AAT46414.1\n",
+ "QGC48744.1 AAT46415.1\n",
+ "AAT46413.1 AAT46414.1\n",
+ "AAT46413.1 AAT46415.1\n",
+ "AAT46414.1 AAT46415.1\n"
+ ]
+ }
+ ],
+ "source": [
+ "for alignment in alignments:\n",
+ " print(\n",
+ " alignment.aligned_sequences[0].source_id,\n",
+ " alignment.aligned_sequences[1].source_id,\n",
+ " )"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 12,
+ "metadata": {},
+ "outputs": [
+ {
+ "ename": "NameError",
+ "evalue": "name 'construct_network' is not defined",
+ "output_type": "error",
+ "traceback": [
+ "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
+ "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
+ "Cell \u001b[0;32mIn[12], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m \u001b[43mconstruct_network\u001b[49m(alignments, \u001b[38;5;241m0\u001b[39m)\n",
+ "\u001b[0;31mNameError\u001b[0m: name 'construct_network' is not defined"
+ ]
+ }
+ ],
+ "source": [
+ "construct_network(alignments, 0)"
]
}
],
diff --git a/pyeed/network/network.py b/pyeed/network/network.py
index 2b9ba4d9..4e1750bf 100644
--- a/pyeed/network/network.py
+++ b/pyeed/network/network.py
@@ -1,204 +1,236 @@
-from typing import List
+from typing import List, Optional
import networkx as nx
import plotly.graph_objects as go
+from pydantic import BaseModel, Field
+from pyeed import network
+from pyeed.core.abstractsequence import AbstractSequence
+from pyeed.core.pairwisealignment import PairwiseAlignment
from pyeed.core.proteininfo import ProteinInfo
from pyeed.core.alignment import Alignment
-def pairwise_network(
- alignments: List[Alignment],
- weight: str = "identity",
- cutoff: float = None,
- label: str = "accession_id",
- color: str = "name",
-) -> None:
- """Takes a list of `Alignment`, constructs a network graph,
- whereas the edges of the graph are weighted with an attribute of the
- `Alignment` object. Visualizes the network graph.
-
- Args:
- alignments (List[Alignment]): List of pairwise alignments.
- weight (str, optional): Attribute of `Alignment` to weight the edges.
- Defaults to "identity".
- cutoff (float, optional): Sequences with a weight higher than the cutoff are connected
- in the network. Defaults to None.
- label (str, optional): Node labe in the graph. Defaults to "accession_id".
- color (str, optional): Attribute of `ProteinInfo` co colorize nodes. Defaults to "name".
-
- Raises:
- ValueError: If 'weights' is not one of "identity", "score", "gaps", or "mismatches".
- ValueError: If 'label' is not one of "name", "organism", "ec_number",
- "mol_weight", or "accession_id".
- """
-
- # Validate weights
- weights = ["identity", "score", "gaps", "mismatches"]
- if weight not in weights:
- raise ValueError(
- f"'weight' to parameterize network must be an alignment property ({weights})"
- )
-
- # Validate labels
- labels = ["name", "organism", "ec_number", "mol_weight", "accession_id"]
- if label not in labels:
- raise ValueError(
- f"'label' to parameterize network must be an alignment property ({labels})"
- )
-
- graph = construct_network(alignments, cutoff=cutoff)
-
- graph = position_nodes_and_edges(graph, weight=weight)
-
- visualize_network(graph, label=label, color=color)
-
-
-def construct_network(alignments: List[Alignment], cutoff: float) -> nx.Graph:
- """Maps properties of alignments to a network graph."""
- graph = nx.Graph()
-
- sequences = _get_unique_sequences(alignments)
-
- # Add nodes and assign node attributes
- for sequence in sequences:
- graph.add_node(
- node_for_adding=sequence.source_id,
- name=sequence.name,
- accession_id=sequence.source_id,
- organism=sequence.organism.name,
- ec_number=sequence.ec_number,
- mol_weight=sequence.mol_weight,
- )
-
- # Add edges and assign edge attributes
- if cutoff != None:
- for alignment in alignments:
- if alignment.identity >= cutoff:
- graph.add_edge(
- alignment.reference_seq.source_id,
- alignment.query_seq.source_id,
- identity=alignment.identity,
- gaps=1 / (alignment.gaps + 1),
- mismatches=1 / (alignment.mismatches + 1),
- score=alignment.score,
- )
- else:
- for alignment in alignments:
- graph.add_edge(
- alignment.reference_seq.source_id,
- alignment.query_seq.source_id,
- identity=alignment.identity,
- gaps=1 / (alignment.gaps + 1),
- mismatches=1 / (alignment.mismatches + 1),
- score=alignment.score,
- )
+class SequenceNetwork(BaseModel):
- return graph
-
-
-def visualize_network(graph: nx.Graph, label: str, color: str):
- """Visualizes a network graph."""
- # TODO: Refactor coloration of nodes
- # TODO: Add ability to colorize edges
-
- colors = ["blue", "red", "green", "orange", "purple", "pink", "brown", "yellow"]
- traces = []
- # Add edges
- for edge in graph.edges:
- traces.append(
- go.Scatter(
- x=graph.edges[edge]["x_pos"],
- y=graph.edges[edge]["y_pos"],
- mode="lines",
- line=dict(
- width=1,
- # colorscale="YlGnBu",
- # colorbar=dict(title='Heatmap Colorscale')
- color="rgba(128, 128, 128, 0.1)",
- ),
- hoverinfo="text",
- text=graph.edges[edge]["gaps"],
- )
- )
-
- # Add nodes
- color_dict = {}
- for _, data in graph.nodes(data=True):
- if data[color] not in color_dict:
- color_dict[data[color]] = colors[len(color_dict)]
-
- traces.append(
- go.Scatter(
- x=[data["x_pos"]],
- y=[data["y_pos"]],
- mode="markers",
- hoverinfo="text",
- marker=dict(
- # showscale=True,
- # colorscale="Viridis",
- size=10,
- # colorbar=dict(thickness=15, title=""),
- color=color_dict[data[color]],
- ),
- text=data[label],
- )
- )
-
- # Plot figure
- fig = go.Figure(
- data=traces,
- layout=go.Layout(
- plot_bgcolor="white",
- showlegend=False,
- hovermode="closest",
- margin=dict(b=0, l=0, r=0, t=0),
- ),
+ sequences: List[AbstractSequence] = Field(
+ ...,
+ description="List of sequences to be compared",
)
- fig.update_xaxes(visible=False)
- fig.update_yaxes(visible=False)
- print(color_dict)
-
- fig.show()
-
-
-def position_nodes_and_edges(graph: nx.Graph, weight: str) -> nx.Graph:
- """Calculates node positions based on weight metric and
- adds position information of nodes and edges to the respective
- entry in the graph."""
- positions = nx.spring_layout(graph, weight=weight)
+ pairwise_alignments: List[PairwiseAlignment] = Field(
+ ...,
+ description="List of pairwise alignments",
+ )
- # Add node position as coordinates
- for node in graph.nodes():
- graph.nodes[node]["x_pos"] = positions[node][0]
- graph.nodes[node]["y_pos"] = positions[node][1]
+ weight: str = Field(
+ ...,
+ description="Attribute of Alignment to weight the edges",
+ )
- # Add edge positions as coordinates
- for edge in graph.edges():
- graph.edges[edge]["x_pos"] = [
- graph.nodes[edge[0]]["x_pos"],
- graph.nodes[edge[1]]["x_pos"],
- ]
- graph.edges[edge]["y_pos"] = [
- graph.nodes[edge[0]]["y_pos"],
- graph.nodes[edge[1]]["y_pos"],
- ]
+ color: str = Field(
+ ...,
+ description="Attribute of ProteinInfo to colorize nodes",
+ )
- return graph
+ threshold: Optional[float] = Field(
+ default=None,
+ description="Sequences with a weight higher than the threshold are connected in the network",
+ )
+ label: str = Field(
+ ...,
+ description="Node label in the graph",
+ )
-def _get_unique_sequences(alignments: List[Alignment]) -> List[ProteinInfo]:
- """Gets unique sequences from a list of alignments."""
+ def graph(self) -> nx.Graph:
+ """Maps properties of alignments to a network graph."""
+ graph = nx.Graph()
- sequence_infos = []
- added_ids = set()
- for alignment in alignments:
- if alignment.reference_seq.source_id not in added_ids:
- sequence_infos.append(alignment.reference_seq)
- added_ids.add(alignment.reference_seq.source_id)
+ # Add nodes and assign node attributes
+ for sequence in self.sequences:
+ graph.add_node(
+ sequence.source_id,
+ name=sequence.name,
+ organism=sequence.organism,
+ )
- if alignment.query_seq.source_id not in added_ids:
- sequence_infos.append(alignment.query_seq)
- added_ids.add(alignment.query_seq.source_id)
+ # Add edges and assign edge attributes
+ if self.threshold != None:
+ for alignment in self.pairwise_alignments:
+ print(alignment.id)
+ if alignment.identity >= self.threshold:
+ graph.add_edge(
+ alignment.input_sequences[0].source_id,
+ alignment.input_sequences[1].source_id,
+ identity=alignment.identity,
+ gaps=1 / (alignment.gaps + 1),
+ mismatches=1 / (alignment.mismatches + 1),
+ score=alignment.score,
+ )
+ else:
+ for alignment in self.pairwise_alignments:
+ print()
+ graph.add_edge(
+ alignment.input_sequences[0].source_id,
+ alignment.input_sequences[1].source_id,
+ identity=alignment.identity,
+ gaps=1 / (alignment.gaps + 1),
+ mismatches=1 / (alignment.mismatches + 1),
+ score=alignment.score,
+ )
- return sequence_infos
+ return graph
+
+ # def pairwise_network(
+ # alignments: List[Alignment],
+ # weight: str = "identity",
+ # cutoff: float = None,
+ # label: str = "accession_id",
+ # color: str = "name",
+ # ) -> None:
+ # """Takes a list of `Alignment`, constructs a network graph,
+ # whereas the edges of the graph are weighted with an attribute of the
+ # `Alignment` object. Visualizes the network graph.
+
+ # Args:
+ # alignments (List[Alignment]): List of pairwise alignments.
+ # weight (str, optional): Attribute of `Alignment` to weight the edges.
+ # Defaults to "identity".
+ # cutoff (float, optional): Sequences with a weight higher than the cutoff are connected
+ # in the network. Defaults to None.
+ # label (str, optional): Node labe in the graph. Defaults to "accession_id".
+ # color (str, optional): Attribute of `ProteinInfo` co colorize nodes. Defaults to "name".
+
+ # Raises:
+ # ValueError: If 'weights' is not one of "identity", "score", "gaps", or "mismatches".
+ # ValueError: If 'label' is not one of "name", "organism", "ec_number",
+ # "mol_weight", or "accession_id".
+ # """
+
+ # # Validate weights
+ # weights = ["identity", "score", "gaps", "mismatches"]
+ # if weight not in weights:
+ # raise ValueError(
+ # f"'weight' to parameterize network must be an alignment property ({weights})"
+ # )
+
+ # # Validate labels
+ # labels = ["name", "organism", "ec_number", "mol_weight", "accession_id"]
+ # if label not in labels:
+ # raise ValueError(
+ # f"'label' to parameterize network must be an alignment property ({labels})"
+ # )
+
+ # graph = construct_network(alignments, cutoff=cutoff)
+
+ # graph = position_nodes_and_edges(graph, weight=weight)
+
+ # visualize_network(graph, label=label, color=color)
+
+
+# def visualize_network(graph: nx.Graph, label: str, color: str):
+# """Visualizes a network graph."""
+# # TODO: Refactor coloration of nodes
+# # TODO: Add ability to colorize edges
+
+# colors = ["blue", "red", "green", "orange", "purple", "pink", "brown", "yellow"]
+# traces = []
+# # Add edges
+# for edge in graph.edges:
+# traces.append(
+# go.Scatter(
+# x=graph.edges[edge]["x_pos"],
+# y=graph.edges[edge]["y_pos"],
+# mode="lines",
+# line=dict(
+# width=1,
+# # colorscale="YlGnBu",
+# # colorbar=dict(title='Heatmap Colorscale')
+# color="rgba(128, 128, 128, 0.1)",
+# ),
+# hoverinfo="text",
+# text=graph.edges[edge]["gaps"],
+# )
+# )
+
+# # Add nodes
+# color_dict = {}
+# for _, data in graph.nodes(data=True):
+# if data[color] not in color_dict:
+# color_dict[data[color]] = colors[len(color_dict)]
+
+# traces.append(
+# go.Scatter(
+# x=[data["x_pos"]],
+# y=[data["y_pos"]],
+# mode="markers",
+# hoverinfo="text",
+# marker=dict(
+# # showscale=True,
+# # colorscale="Viridis",
+# size=10,
+# # colorbar=dict(thickness=15, title=""),
+# color=color_dict[data[color]],
+# ),
+# text=data[label],
+# )
+# )
+
+# # Plot figure
+# fig = go.Figure(
+# data=traces,
+# layout=go.Layout(
+# plot_bgcolor="white",
+# showlegend=False,
+# hovermode="closest",
+# margin=dict(b=0, l=0, r=0, t=0),
+# ),
+# )
+# fig.update_xaxes(visible=False)
+# fig.update_yaxes(visible=False)
+# print(color_dict)
+
+# fig.show()
+
+
+# def position_nodes_and_edges(graph: nx.Graph, weight: str) -> nx.Graph:
+# """Calculates node positions based on weight metric and
+# adds position information of nodes and edges to the respective
+# entry in the graph."""
+
+# positions = nx.spring_layout(graph, weight=weight)
+
+# # Add node position as coordinates
+# for node in graph.nodes():
+# graph.nodes[node]["x_pos"] = positions[node][0]
+# graph.nodes[node]["y_pos"] = positions[node][1]
+
+# # Add edge positions as coordinates
+# for edge in graph.edges():
+# graph.edges[edge]["x_pos"] = [
+# graph.nodes[edge[0]]["x_pos"],
+# graph.nodes[edge[1]]["x_pos"],
+# ]
+# graph.edges[edge]["y_pos"] = [
+# graph.nodes[edge[0]]["y_pos"],
+# graph.nodes[edge[1]]["y_pos"],
+# ]
+
+# return graph
+
+
+# def _get_unique_sequences(alignments: List[Alignment]) -> List[ProteinInfo]:
+# """Gets unique sequences from a list of alignments."""
+
+# sequence_infos = []
+# added_ids = set()
+# for alignment in alignments:
+# if alignment.reference_seq.source_id not in added_ids:
+# sequence_infos.append(alignment.reference_seq)
+# added_ids.add(alignment.reference_seq.source_id)
+
+# if alignment.query_seq.source_id not in added_ids:
+# sequence_infos.append(alignment.query_seq)
+# added_ids.add(alignment.query_seq.source_id)
+
+# return sequence_infos
From 0548f07072687b942b3a5a7f19151658f961d784 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Fri, 23 Feb 2024 11:15:28 +0100
Subject: [PATCH 09/13] moved test notebooks
---
examples/networks/alignment_network.ipynb | 2394 ----
examples/networks/test.ipynb | 14988 ++++++++++++++++++++
examples/test.ipynb | 333 -
3 files changed, 14988 insertions(+), 2727 deletions(-)
delete mode 100644 examples/networks/alignment_network.ipynb
create mode 100644 examples/networks/test.ipynb
delete mode 100644 examples/test.ipynb
diff --git a/examples/networks/alignment_network.ipynb b/examples/networks/alignment_network.ipynb
deleted file mode 100644
index ce57995b..00000000
--- a/examples/networks/alignment_network.ipynb
+++ /dev/null
@@ -1,2394 +0,0 @@
-{
- "cells": [
- {
- "cell_type": "code",
- "execution_count": 1,
- "metadata": {},
- "outputs": [],
- "source": [
- "from pyEED.core import ProteinInfo\n",
- "from pyEED.alignment.pairwise import multi_pairwise_alignment\n",
- "from pyEED.network import pairwise_network\n",
- "from pyEED.ncbi.utils import load_accessions"
- ]
- },
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "# Visualize networks of pairwise sequence alignments\n",
- "\n",
- "In the following example, a protein BLAST search is conducted based on TEM-1 and TEM-109 variant of beta-lactamase. After pairwise alignment of all sequences, a network is constructed based on the alignment scores and then visualized.\n",
- "\n",
- "## PBLAST search for seed sequences\n",
- "\n",
- "Results from the BLAST search are renamed based to the name of query protein variant."
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 2,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🏃🏼♀️ Running PBLAST\n",
- "╭── protein name: TEM family beta-lactamase\n",
- "├── accession: QGC48744.1\n",
- "├── organism: Escherichia coli\n",
- "├── e-value: 0.05\n",
- "╰── max hits: 15\n"
- ]
- },
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 15/15 [00:11<00:00, 1.30it/s]\n"
- ]
- },
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🎉 Done\n",
- "\n",
- "🏃🏼♀️ Running PBLAST\n",
- "╭── protein name: beta-lactamase TEM-109\n",
- "├── accession: AAT46413.1\n",
- "├── organism: Escherichia coli\n",
- "├── e-value: 0.05\n",
- "╰── max hits: 15\n"
- ]
- },
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 15/15 [00:13<00:00, 1.13it/s]"
- ]
- },
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🎉 Done\n",
- "\n"
- ]
- },
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "\n"
- ]
- }
- ],
- "source": [
- "tem1 = ProteinInfo.from_ncbi(\"QGC48744.1\")\n",
- "tem109 = ProteinInfo.from_ncbi(\"AAT46413.1\")\n",
- "\n",
- "blast_results = []\n",
- "for tem in [tem1, tem109]:\n",
- " sequences = tem.pblast(\n",
- " e_value=0.05, n_hits=15, api_key=\"161e6eb71dcc94511d2d0e2fc5336c1af709\"\n",
- " )\n",
- "\n",
- " for sequence in sequences:\n",
- " sequence.name = tem.name\n",
- "\n",
- " blast_results.extend(sequences)\n",
- " blast_results.append(tem)"
- ]
- },
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "## Pairwise alignment of unique sequence pairs"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 3,
- "metadata": {},
- "outputs": [
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⛓️ Aligning sequences: 100%|██████████| 496/496 [00:01<00:00, 342.87it/s]\n"
- ]
- }
- ],
- "source": [
- "alignments = multi_pairwise_alignment(\n",
- " blast_results,\n",
- " mode=\"global\",\n",
- " match=1,\n",
- " mismatch=-1,\n",
- " gap_open=-1,\n",
- " gap_extend=0,\n",
- " n_jobs=8,\n",
- ")"
- ]
- },
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "## Visualize the alignment network"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 4,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "{'TEM family beta-lactamase': 'blue', 'beta-lactamase TEM-109': 'red'}\n"
- ]
- },
- {
- "data": {
- "application/vnd.plotly.v1+json": {
- "config": {
- "plotlyServerURL": "https://plot.ly"
- },
- "data": [
- {
- "hoverinfo": "text",
- "line": {
- "color": "rgba(128, 128, 128, 0.1)",
- "width": 1
- },
- "mode": "lines",
- "text": "1.0",
- "type": "scatter",
- "x": [
- -0.6914588236656009,
- -0.7475822584708567
- ],
- "y": [
- 0.6937671259213628,
- 0.6618414989828777
- ]
- },
- {
- "hoverinfo": "text",
- "line": {
- "color": "rgba(128, 128, 128, 0.1)",
- "width": 1
- },
- "mode": "lines",
- "text": "1.0",
- "type": "scatter",
- "x": [
- -0.2448563136899791,
- -0.1203321469905742
- ],
- "y": [
- 0.14734002900774362,
- 0.0763339976053082
- ]
- },
- {
- "hoverinfo": "text",
- "line": {
- "color": "rgba(128, 128, 128, 0.1)",
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- "x": [
- -0.0811932367392075,
- -0.1203321469905742
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- "y": [
- 0.17382567240497152,
- 0.0763339976053082
- ]
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- {
- "hoverinfo": "text",
- "line": {
- "color": "rgba(128, 128, 128, 0.1)",
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- "bgcolor": "#E5ECF6",
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- ],
- "source": [
- "pairwise_network(\n",
- " alignments=alignments,\n",
- " weight=\"identity\",\n",
- " color=\"name\",\n",
- " label=\"organism\",\n",
- " cutoff=0.996,\n",
- ")"
- ]
- }
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diff --git a/examples/networks/test.ipynb b/examples/networks/test.ipynb
new file mode 100644
index 00000000..dfdaca10
--- /dev/null
+++ b/examples/networks/test.ipynb
@@ -0,0 +1,14988 @@
+{
+ "cells": [
+ {
+ "cell_type": "markdown",
+ "metadata": {},
+ "source": [
+ "# Network Visualization"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 1,
+ "metadata": {},
+ "outputs": [],
+ "source": [
+ "%reload_ext autoreload\n",
+ "%autoreload 2\n",
+ "from pyeed.core import ProteinInfo, Alignment\n",
+ "from pyeed.aligners import ClustalOmega, PairwiseAligner\n",
+ "from pyeed.network import SequenceNetwork"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 2,
+ "metadata": {},
+ "outputs": [],
+ "source": [
+ "# Get a query sequence from NCBI\n",
+ "metTK = ProteinInfo.from_ncbi(\"WP_011249500.1\")"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 3,
+ "metadata": {},
+ "outputs": [
+ {
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "🏃 Running BLAST\n"
+ ]
+ },
+ {
+ "name": "stderr",
+ "output_type": "stream",
+ "text": [
+ "⬇️ Fetching protein sequences: 100%|█████████▉| 499/500 [00:53<00:00, 9.38it/s]\n"
+ ]
+ }
+ ],
+ "source": [
+ "# Run local blastp search\n",
+ "blast_results = metTK.blastp(\n",
+ " db_path=\"/Users/max/Documents/GitHub/blast-db/data/source\",\n",
+ " n_hits=500,\n",
+ " ncbi_key=\"fc08205c4aad544871863f0eb134f5524707\",\n",
+ ")"
+ ]
+ },
+ {
+ "cell_type": "markdown",
+ "metadata": {},
+ "source": [
+ "## MSA with Clustal Omega"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 4,
+ "metadata": {},
+ "outputs": [
+ {
+ "name": "stdout",
+ "output_type": "stream",
+ "text": [
+ "🏃 Running CLUSTALO\n",
+ "\u001b[4mStandardNumbering\u001b[0m\n",
+ "├── \u001b[94mid\u001b[0m = standardnumbering456\n",
+ "├── \u001b[94mreference_id\u001b[0m = MBP1912539.1\n",
+ "├── \u001b[94mnumbered_id\u001b[0m = WP_254809959.1\n",
+ "└── \u001b[94mnumbering\u001b[0m = [0.1, 0.2, 0.3, 0.4, 0.5, ...]\n",
+ "\n"
+ ]
+ }
+ ],
+ "source": [
+ "alignment = Alignment.from_sequences(blast_results, aligner=ClustalOmega)\n",
+ "print(alignment.standard_numberings[456])"
+ ]
+ },
+ {
+ "cell_type": "markdown",
+ "metadata": {},
+ "source": [
+ "## Multi Pairwise Alignment"
+ ]
+ },
+ {
+ "cell_type": "code",
+ "execution_count": 5,
+ "metadata": {},
+ "outputs": [
+ {
+ "name": "stderr",
+ "output_type": "stream",
+ "text": [
+ "⛓️ Running pairwise alignments: 100%|██████████| 124251/124251 [00:31<00:00, 3922.61it/s]\n"
+ ]
+ }
+ ],
+ "source": [
+ "# Create and run alignment\n",
+ "multi_parwise_alignments = Alignment.from_sequences(\n",
+ " blast_results, aligner=PairwiseAligner)"
+ ]
+ },
+ {
+ "cell_type": "code",
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+ [
+ 0.1111111111111111,
+ "#46039f"
+ ],
+ [
+ 0.2222222222222222,
+ "#7201a8"
+ ],
+ [
+ 0.3333333333333333,
+ "#9c179e"
+ ],
+ [
+ 0.4444444444444444,
+ "#bd3786"
+ ],
+ [
+ 0.5555555555555556,
+ "#d8576b"
+ ],
+ [
+ 0.6666666666666666,
+ "#ed7953"
+ ],
+ [
+ 0.7777777777777778,
+ "#fb9f3a"
+ ],
+ [
+ 0.8888888888888888,
+ "#fdca26"
+ ],
+ [
+ 1,
+ "#f0f921"
+ ]
+ ],
+ "sequentialminus": [
+ [
+ 0,
+ "#0d0887"
+ ],
+ [
+ 0.1111111111111111,
+ "#46039f"
+ ],
+ [
+ 0.2222222222222222,
+ "#7201a8"
+ ],
+ [
+ 0.3333333333333333,
+ "#9c179e"
+ ],
+ [
+ 0.4444444444444444,
+ "#bd3786"
+ ],
+ [
+ 0.5555555555555556,
+ "#d8576b"
+ ],
+ [
+ 0.6666666666666666,
+ "#ed7953"
+ ],
+ [
+ 0.7777777777777778,
+ "#fb9f3a"
+ ],
+ [
+ 0.8888888888888888,
+ "#fdca26"
+ ],
+ [
+ 1,
+ "#f0f921"
+ ]
+ ]
+ },
+ "colorway": [
+ "#636efa",
+ "#EF553B",
+ "#00cc96",
+ "#ab63fa",
+ "#FFA15A",
+ "#19d3f3",
+ "#FF6692",
+ "#B6E880",
+ "#FF97FF",
+ "#FECB52"
+ ],
+ "font": {
+ "color": "#2a3f5f"
+ },
+ "geo": {
+ "bgcolor": "white",
+ "lakecolor": "white",
+ "landcolor": "#E5ECF6",
+ "showlakes": true,
+ "showland": true,
+ "subunitcolor": "white"
+ },
+ "hoverlabel": {
+ "align": "left"
+ },
+ "hovermode": "closest",
+ "mapbox": {
+ "style": "light"
+ },
+ "paper_bgcolor": "white",
+ "plot_bgcolor": "#E5ECF6",
+ "polar": {
+ "angularaxis": {
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": ""
+ },
+ "bgcolor": "#E5ECF6",
+ "radialaxis": {
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": ""
+ }
+ },
+ "scene": {
+ "xaxis": {
+ "backgroundcolor": "#E5ECF6",
+ "gridcolor": "white",
+ "gridwidth": 2,
+ "linecolor": "white",
+ "showbackground": true,
+ "ticks": "",
+ "zerolinecolor": "white"
+ },
+ "yaxis": {
+ "backgroundcolor": "#E5ECF6",
+ "gridcolor": "white",
+ "gridwidth": 2,
+ "linecolor": "white",
+ "showbackground": true,
+ "ticks": "",
+ "zerolinecolor": "white"
+ },
+ "zaxis": {
+ "backgroundcolor": "#E5ECF6",
+ "gridcolor": "white",
+ "gridwidth": 2,
+ "linecolor": "white",
+ "showbackground": true,
+ "ticks": "",
+ "zerolinecolor": "white"
+ }
+ },
+ "shapedefaults": {
+ "line": {
+ "color": "#2a3f5f"
+ }
+ },
+ "ternary": {
+ "aaxis": {
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": ""
+ },
+ "baxis": {
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": ""
+ },
+ "bgcolor": "#E5ECF6",
+ "caxis": {
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": ""
+ }
+ },
+ "title": {
+ "x": 0.05
+ },
+ "xaxis": {
+ "automargin": true,
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": "",
+ "title": {
+ "standoff": 15
+ },
+ "zerolinecolor": "white",
+ "zerolinewidth": 2
+ },
+ "yaxis": {
+ "automargin": true,
+ "gridcolor": "white",
+ "linecolor": "white",
+ "ticks": "",
+ "title": {
+ "standoff": 15
+ },
+ "zerolinecolor": "white",
+ "zerolinewidth": 2
+ }
+ }
+ },
+ "xaxis": {
+ "visible": false
+ },
+ "yaxis": {
+ "visible": false
+ }
+ }
+ }
+ },
+ "metadata": {},
+ "output_type": "display_data"
+ }
+ ],
+ "source": [
+ "n = SequenceNetwork(\n",
+ " sequences=blast_results,\n",
+ " pairwise_alignments=multi_parwise_alignments,\n",
+ " threshold=0.65,\n",
+ " weight=\"identity\",\n",
+ " dimensions=3,\n",
+ " color=\"taxonomy_id\",\n",
+ ")\n",
+ "n.visualize()"
+ ]
+ }
+ ],
+ "metadata": {
+ "kernelspec": {
+ "display_name": "pye",
+ "language": "python",
+ "name": "python3"
+ },
+ "language_info": {
+ "codemirror_mode": {
+ "name": "ipython",
+ "version": 3
+ },
+ "file_extension": ".py",
+ "mimetype": "text/x-python",
+ "name": "python",
+ "nbconvert_exporter": "python",
+ "pygments_lexer": "ipython3",
+ "version": "3.10.13"
+ }
+ },
+ "nbformat": 4,
+ "nbformat_minor": 2
+}
diff --git a/examples/test.ipynb b/examples/test.ipynb
deleted file mode 100644
index dab953cc..00000000
--- a/examples/test.ipynb
+++ /dev/null
@@ -1,333 +0,0 @@
-{
- "cells": [
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "# Test Aligners"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 1,
- "metadata": {},
- "outputs": [],
- "source": [
- "%reload_ext autoreload\n",
- "%autoreload 2\n",
- "from pyeed.core import ProteinInfo\n",
- "from pyeed.core import Alignment\n",
- "from pyeed.aligners import ClustalOmega"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 2,
- "metadata": {},
- "outputs": [],
- "source": [
- "# Get a query sequence from NCBI\n",
- "ald1 = ProteinInfo.from_ncbi(\"UCS38941.1\")"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 3,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🏃 Running BLAST\n"
- ]
- },
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 100/100 [00:06<00:00, 14.97it/s]\n"
- ]
- }
- ],
- "source": [
- "# Run local blastp search\n",
- "blast_results = ald1.blastp(\n",
- " db_path=\"/Users/max/Documents/GitHub/blast-db/data/source\",\n",
- " n_hits=100,\n",
- ")"
- ]
- },
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "## MSA with Clustal Omega"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 4,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🏃 Running CLUSTALO\n"
- ]
- },
- {
- "data": {
- "text/plain": [
- "Alignment(id='alignment0', method='CLUSTALO', consensus='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', input_sequences=[Sequence(id='sequence0', source_id='BAH60832.1', sequence='MSASEMRAASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDNENKELVSQPHNYGHTSE'), Sequence(id='sequence1', source_id='CAI4663910.1', sequence='MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQDRKSHNIRKPSSSPSSKAPSPGVNT'), Sequence(id='sequence2', source_id='EJT44931.1', sequence='MTTPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQDRKNHTVKKPSSSPSSKPPSPGVNI'), Sequence(id='sequence3', source_id='XP_037139093.1', sequence='MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRPSPSARTSFS'), Sequence(id='sequence4', source_id='XP_003680887.1', sequence='MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRSSPSTRSSTS'), Sequence(id='sequence5', source_id='XP_037144827.1', sequence='MSQEYRTRSRSRSFSDQAATQEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIKNSNTNVTTESRRKSPTYTQ'), Sequence(id='sequence6', source_id='AQZ18344.1', sequence='MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG'), Sequence(id='sequence7', source_id='XP_002495560.1', sequence='MDNSDQEVQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR'), Sequence(id='sequence8', source_id='XP_003673548.1', sequence='MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS'), Sequence(id='sequence9', source_id='XP_003958955.1', sequence='MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLKTPRA'), Sequence(id='sequence10', source_id='XP_001644471.1', sequence='MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASASSSASSPSAST'), Sequence(id='sequence11', source_id='XP_003684279.1', sequence='MPYRENRNASSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence12', source_id='SMN18735.1', sequence='MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSSSISPPKSKGTTAS'), Sequence(id='sequence13', source_id='CAD1779387.1', sequence='MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTSSTSTSQVKAKETTAT'), Sequence(id='sequence14', source_id='KAG0666170.1', sequence='MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS'), Sequence(id='sequence15', source_id='XP_022464898.1', sequence='MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERTPVSSQQ'), Sequence(id='sequence16', source_id='XP_003669861.1', sequence='MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK'), Sequence(id='sequence17', source_id='XP_003678517.1', sequence='MASEHRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK'), Sequence(id='sequence18', source_id='KAG0659075.1', sequence='MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSSHGHTSNNNNNNNTPIQASPIAVRSSYNHRHH'), Sequence(id='sequence19', source_id='XP_451758.1', sequence='MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSPKRQVHTPPPSS'), Sequence(id='sequence20', source_id='NP_984991.1', sequence='MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPSEYTHHGRYRQPEHIRNMAEQ'), Sequence(id='sequence21', source_id='XP_017989070.1', sequence='MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVMAASSGYSPTSATVEQGQYRQSERAQHTASEQ'), Sequence(id='sequence22', source_id='KAG0673910.1', sequence='MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVHTPPPSS'), Sequence(id='sequence23', source_id='SMN21971.1', sequence='MNSEKNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL'), Sequence(id='sequence24', source_id='KAG0661436.1', sequence='MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN'), Sequence(id='sequence25', source_id='SCV02624.1', sequence='MSTNEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSRTPSPHRSP'), Sequence(id='sequence26', source_id='SCV99388.1', sequence='MSLATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS'), Sequence(id='sequence27', source_id='CUS20182.1', sequence='MSMVSGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS'), Sequence(id='sequence28', source_id='XP_045933944.1', sequence='MHFQQQQQQHYHTPLRHGSDPAQHITNNSEEHINNYGNNTVDTPQQLRHTSAMTVINSSQAATNNNYSDNNNNTSPVRGTTSTAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN'), Sequence(id='sequence29', source_id='KAA8901327.1', sequence='MSTPSSPSGGGSKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW'), Sequence(id='sequence30', source_id='KAF8417303.1', sequence='MSDSSTIASGSGAGGSYHHQQASTSSAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV'), Sequence(id='sequence31', source_id='KAF3929277.1', sequence='MTTTPPTKRETSPVSPLRASFANLNTEDHSQATAAIRAQAGHTRHESLEKYTRRDSTASENRNEEGYRERGSISSQSGAAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence32', source_id='OEJ86227.1', sequence='MTEYENGQQQQRERIRGQERESYDEQERESYDEQERERIREQERRINNEQQRRVNNEQQRRXNNQQRSTTNDNVSSNKNTHKDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH'), Sequence(id='sequence33', source_id='XP_046060918.1', sequence='MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS'), Sequence(id='sequence34', source_id='EPS36031.1', sequence='MTTTPPTKRDASPVSPLRASFANLNTDDHTSATAAIRAAAGHTRHESLEKYTRRDSTASENRPEEGYRERGSISSQGGSAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence35', source_id='KAI5807151.1', sequence='MHELPLAPSLPPPQSPPTPDRYSQGAARHYHSNSAASAPAMIGDAAGAYYRGSPPPPMPQQPYVPRDRSSESYHNGSSAQQQQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence36', source_id='XP_011117899.1', sequence='MTTTPPTKRESSPVSPLRASFANLNADDHSSATAAIRAAAGHTRHESLEKYTRRDSTASENRNDESYRDRSSVSSQGGSGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR'), Sequence(id='sequence37', source_id='KAI1438264.1', sequence='MEQDLHTTPGADLEPHGLPDDGSISSIEDTPEAASSLNGHETYHQHPQSLDYVVSSSQNTDETDPNAQYETVPATSQAQSISRPPSGLSGAGGDRQAAHSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence38', source_id='XP_022456167.1', sequence='MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV'), Sequence(id='sequence39', source_id='KAF3908940.1', sequence='MTTTPPTKRDVSPVSPLRASFANLNTTDDGQSATAAIRASAGHTRHESLEKYTRRDSTASESRNEDGYRERSSISSQGGSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR'), Sequence(id='sequence40', source_id='XP_006693239.1', sequence='MERDQLAAPAPSESAASDYRDHSLADAEVAPSSDCENNGFHDHHYSQSQHYDQDDAAESEPTARYNTPSGSGQQISRPPSGLSGERGAGYATDQGSRAGSNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV'), Sequence(id='sequence41', source_id='EWC45326.1', sequence='MATTPPTKRDTSPVSPLRASFANLNTTDDGQQSAAAAIRAAAGHTRHESLEKYTRRDSTASESRNDDGYRERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR'), Sequence(id='sequence42', source_id='KAF3930522.1', sequence='MTTTPPTKQGSRNVSPVSPLRASFANLNTTDENHSSATAAIRAAAGHTRHESLEKYTRRDSNASESKNEDGYRERSSVSSQGGSSQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR'), Sequence(id='sequence43', source_id='KAF8249497.1', sequence='MQQHDDDALPQPQTTELPLAPSLPPPVALAHSPPTPRRRNSSPTRHYHSSSNASGAPPYIGSPGSVESAQYYNSQGSPPTPAAPHQQQQFATSRADGGYHNGGGYAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence44', source_id='XP_002174495.1', sequence='MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV'), Sequence(id='sequence45', source_id='PRP83484.1', sequence='MGDQNDTEARIGHSRLPFFIMSGDGEYTGSGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS'), Sequence(id='sequence46', source_id='GAA97202.1', sequence='MASSTSTGAGSSSSRQRQESYRSSHSQQSSSQHAPAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI'), Sequence(id='sequence47', source_id='OBA26219.1', sequence='MESMLQSHNRRRHTNSMSISGSSNNNVHSELRQNNNNRISSMPSSQPASNSNNKPVDNIKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR'), Sequence(id='sequence48', source_id='KAI1823332.1', sequence='MEQDFHAVPAPDSEPHDHPDDGLGGLEESPDIAPGSNGHELYHQHPQSLDYVISNNQNIDDVDPNAPYEAVATTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence49', source_id='CDO57487.1', sequence='MSIPSIYPNHKPTGMYTGQFISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW'), Sequence(id='sequence50', source_id='KAI2629167.1', sequence='MDQDPMATPIPHDVHDDTLGGIEGSMHLPNEPHNHETHHRQSQSLDQGLANNAHPDEVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence51', source_id='KAI5811198.1', sequence='MSNDPLPTIPSATSSTVDLSNGNDGSAQNENEPPHRSQHHTGMTSIHLNDPTSQSNAAASYSQTHSGATMLSSGSGATGSFQQAGGPSSGGPAGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV'), Sequence(id='sequence52', source_id='KAG9017701.1', sequence='MSTAASGSGAPPATPLSAASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ'), Sequence(id='sequence53', source_id='OTA67948.1', sequence='MHFPGHLPDEPSSSSHEPHHRQSQSLDQGLANSAHPHPHPDDIDPNAQYEAQQYDPPQQSTQRPPSSMSSTGERQYTEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence54', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVPAAAAAQVPLPHSLSPPLQIDPHDDTLSSAGTVSHQALPDHNNFHEHNGYHDQPQHPIQFQPLDHSVNNSPRSYYPADQTDSEPTARYATPPVAAPAISRPSSGLSGQGAGYGADHVSRAGSNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence55', source_id='ORX96310.1', sequence='MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID'), Sequence(id='sequence56', source_id='XP_028477951.1', sequence='MTDPGYASSGSGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL'), Sequence(id='sequence57', source_id='XP_024666830.1', sequence='MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW'), Sequence(id='sequence58', source_id='KAI0099584.1', sequence='MHIPGHLPGESSSSHEPHHRQSQSLDQGLANSAPPLPDDIDPNAQYEAHQYDPPQQPVQRPASSMSSTGERQYNEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence59', source_id='KAI1801530.1', sequence='MHIAGEPGVHEPHHRQSRSLDQGLANSAHADDIDTHAVDPHAIDPIAVDHNAQYEAHSYEPPAQSMSRPASSSGTGERHLNGEASREGNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence60', source_id='KAF9351078.1', sequence='MSDTPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY'), Sequence(id='sequence61', source_id='KAF9160900.1', sequence='MAATSESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI'), Sequence(id='sequence62', source_id='KAG0263740.1', sequence='MAAAGDSGKKSSSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK'), Sequence(id='sequence63', source_id='KAI1135662.1', sequence='MEQDPVAAPVPHDIHEDTIGGIEGSMHIPAEPSTSHEPHRHRQSQSLDRGLASSKHPEDIDPNAQYDTPQYDPPQQSMPRPASSSSAGERHYAEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence64', source_id='XP_045969802.1', sequence='MTTTPPPLENNGSLPSHIDIDVAATPRQEHYTSSSDPSLAFSPQDSNSPSRANIGDDQRHSGTPPLSQSQLYGNGGGMNSFTSAAGAAAGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence65', source_id='KAI1414505.1', sequence='MHFSGEPSSSHEPLHRQSQSLDQGLANSAHPHPDDIDPNAQYEAHQYDPPQQSMQRPTSSMSSGGERHYTEQAPRESNGTDRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence66', source_id='KAG0239750.1', sequence='MATLGDSGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY'), Sequence(id='sequence67', source_id='XP_044688071.1', sequence='MTTTPPPPENNGSLPSHIDVDVAATPRQEHYTSSDPSLTFSPQDSNSPSRAIGDERNSGTPPLSQSQLYGNGGGMNNFTSAAAAAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence68', source_id='RPB01516.1', sequence='MTTTPPLLFSPSPPPPLPDSLYPDEPEEVTTPTATLPPPPPSPPPRQPSPARHQHSGSAPATVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGGGGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence69', source_id='KAG0236582.1', sequence='MAASADSARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS'), Sequence(id='sequence70', source_id='KAH6640987.1', sequence='MEQDQAISPAYAVAPDSALAPARIPSPAGFPTDPHDDTLSGVESVTHQAVPDHHIHEHNGFHEQQHISQLQPLDHNVTNSPRSPYPTDTTDSEPTARYATPPIQAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence71', source_id='XP_002493958.1', sequence='MPDSPRRNQHRRSHSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI'), Sequence(id='sequence72', source_id='KAA8914877.1', sequence='MTTTPPPSRTSTSDMDHSARTPSSSSSSIPEEYIHTELRLAPSLSSLQSPPTPDRGSPSRYHHSHSNSATSAPSDGASYYGGSPPAMRDRDREGYYGNGAGAAGGSGGGAGSSAYNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV'), Sequence(id='sequence73', source_id='XP_018701974.1', sequence='METDDVPAATLHDNLDDTLGGLDGSPQVPSSSHYSNHHHDHQYQNPHHSNNDTHEHEPQSPGGGPSHHQQQHHDEDPPCTRYTPPAPGSSAPASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence74', source_id='KAI2643608.1', sequence='MEHDLHGAPVSGLEPHAHHDDDSLNDADEHSDIASSLNGHESYHQPSQSLDYVLSHGQDTDEADPNSQYETQPTTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence75', source_id='KAG0125076.1', sequence='MTTTPPPLFSPSPPPPLPDSLCPDDPEEVTTPTSNLPPPPLPSPPPRQPSPVRHHHSGPAPAAVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGSGGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence76', source_id='KAH9904989.1', sequence='MEQDPVAAAVPQDGYDDTLGGIEGSPHVGPTQINREKRHQQSQSLDNGLPNNGHADEIDPNARYDTPPNPLQPHSISRPPSGLSGAGDRHNAYSDHASRGSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence77', source_id='VEU24358.1', sequence='MDNRSVSTRIPRSHSTSEALSEEPARSVSSTVDGYDNYYGHQHHHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV'), Sequence(id='sequence78', source_id='KAI1283572.1', sequence='MDTMEQDFHAAPIPGPHEHLDEPLPDTFADVEGGPHVSPSQNGHEVYHHHHQQSQSLDHGLASSQNHDEADLNGRYETPPSTAHPQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence79', source_id='KAI1500557.1', sequence='MMEHDPAFATAPGPHNGIDDMLGGIEGSPTLASGQNGHETYHHHHSQSFDQEIPLNENPDDMDTTAQYDTPPVTAQPQSISRPPSALDGAAGERHASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC'), Sequence(id='sequence80', source_id='KAI2623093.1', sequence='MDQDPITTPVQAPAQDPTPHELHEDTFGGIEGSMHLSGEPGTPEAHHRQSQSLDQGLANSVHPDEVDPNTQYEAHQYDAPPQSMPRPASSMSGAGERQYPEHASRESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence81', source_id='NP_593285.1', sequence='MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR'), Sequence(id='sequence82', source_id='KAI0431960.1', sequence='MDTMEQDFHAAPIPGPHEHLDETLPDTLADVEGAPHVSPSQNGHEVYHHHQQSHSLDQGLANSQTSDEPDLNGRYETPPSTGHAQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence83', source_id='KAH8926511.1', sequence='MSDSAGPLALEKGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV'), Sequence(id='sequence84', source_id='RMJ24013.1', sequence='MNPSYHNGYSSDSHAQYSTGPAGFNPPVHDSTSQDAEQTRLTFSPSITQQPQPPSLSRPSSAFSSGPERHGASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV'), Sequence(id='sequence85', source_id='KAF8931046.1', sequence='MAATGESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN'), Sequence(id='sequence86', source_id='ODQ76250.1', sequence='MSSAAPNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV'), Sequence(id='sequence87', source_id='KXJ93426.1', sequence='MDQEPAALPPTRNPLDVAPDDTLGGIESSPRVYSDPESTIRTHHHSQSLDQGLASSAHYQHNSEDMDHQTRQDTPPIPQQPQSISRPPSGLSGAGDRQPAQYSDHASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence88', source_id='XP_051368163.1', sequence='MDQDLLGTPTAPHDTLDDALAGVEGPLHLASESGNLEPHHRQSQSLDRGLANNAQVDDFDTAVPFDSPQYDTPPPAMQRPASSDSAAGEKQLAEHASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence89', source_id='GES63634.1', sequence='METIHNLNTGVSEPVEQQPQESAFEASPVSHPAGSTDEPTSASVYHRSGYNSDSHAQYSSLATHQPQPPTSSRPSSGLSGPERYGPSQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV'), Sequence(id='sequence90', source_id='RPA74746.1', sequence='MADHHEGSSHSYDRTSHSSRPATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV'), Sequence(id='sequence91', source_id='XP_024675402.1', sequence='MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPAGPYPSHVESVPPEVIPSASTYHAGYSSDSHANYSSNAVDFNSGSEYPPQPRAELPRAQEAVPSMMHPPAAPSSSRPSSGLSSGPDRLGSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL'), Sequence(id='sequence92', source_id='KAH6850716.1', sequence='MEQEQAFNPAYTMAPDPALAPAPIPAPISSPVGLPTDPHDDTLSGVESVTHQALPDHNIHDHNGFHEQQHLVQLQPLDHSVNNSPRSPYPTDTTDSEPTARYATPPIPAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence93', source_id='PHH71636.1', sequence='MEHQQPELDQQPPPLHAAHDSLDDTLGGIEGSPHVAAANNGFHQQSQSLDSAVPNSPRYDDDAANRHTPPVSSAPSLSRPGSQMSNPSSSNPPQQMHGNDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence94', source_id='KAJ3562589.1', sequence='MDTMEQDLHTTPIPGVHEHHHLDDALPDPHADVDARPHSAPGQNGHEVYHQQSHSLDQGIAHGQHPDEADLNGRYDTPPSATHPQSISRPPSGLSGAGGDRQTTYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV'), Sequence(id='sequence95', source_id='RDA84390.1', sequence='MDHQPAADQEQPQELPRPASHDGLDDTLGGIEGSPHPVASSNGFHAHQEAPGSPRYDDDNAARQTPPVSAPLSRPGSQMSNPPQHASGSDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence96', source_id='XP_007413704.1', sequence='MSNMTSSTGPAGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV'), Sequence(id='sequence97', source_id='KAI0376630.1', sequence='MHLPNEPHNHETHHRQSQSLDQGLANNVHPDDVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence98', source_id='XP_047831721.1', sequence='MEQDFHTAPIPGPREHLDALPDTHDTHADVVARPHTAPDQNGHEVYHQQSQSLDQGLSDSQHHDDADVAGRYETHPSTTHPQSISRPPSGLSGAGGDRQATYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence99', source_id='KAI9294962.1', sequence='MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE')], aligned_sequences=[Sequence(id='sequence100', source_id='BAH60832.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSA------------SE-----MR-----A---------ASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDN-ENKELV---------SQPHNYGHTSE---------------------------------'), Sequence(id='sequence101', source_id='CAI4663910.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------A-TPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQD--RKSHNIRKPSS-------------------SPSSKAPSPGVNT-----------------------'), Sequence(id='sequence102', source_id='EJT44931.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------T-TPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQD--RKNHTVKKPSS-------------------SPSSKPPSPGVNI-----------------------'), Sequence(id='sequence103', source_id='XP_037139093.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRP--SPSARTSFS--------------------------------------------------------'), Sequence(id='sequence104', source_id='XP_003680887.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRS--SPSTRSSTS--------------------------------------------------------'), Sequence(id='sequence105', source_id='XP_037144827.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MSQEYR----T---------RSRSRSF------------SD-----QA-----AT-----QEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIK--NSNTNVTTES-----------------------RRKSPTYTQ-----------------------'), Sequence(id='sequence106', source_id='AQZ18344.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG----------------------------------------------------------------------'), Sequence(id='sequence107', source_id='XP_002495560.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDN------------SD-----QE-------------VQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR-----------------------------------------------------------------------'), Sequence(id='sequence108', source_id='XP_003673548.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS----------------------------------------------------------------'), Sequence(id='sequence109', source_id='XP_003958955.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLK-TP-------RA---------------------------------------------------'), Sequence(id='sequence110', source_id='XP_001644471.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASAS--SSA-------S-------------------SPS-------AST-----------------------'), Sequence(id='sequence111', source_id='XP_003684279.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPY------------RE-----NR-----N---------A-SSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence112', source_id='SMN18735.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSS---SISPPKSKGTTAS--------------------------------------------'), Sequence(id='sequence113', source_id='CAD1779387.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTS---STSTSQVKAKETTAT------------------------------------------'), Sequence(id='sequence114', source_id='KAG0666170.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS-------------------------------------------'), Sequence(id='sequence115', source_id='XP_022464898.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERT-PVSSQQ-----------------------------------------------------'), Sequence(id='sequence116', source_id='XP_003669861.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK---------------------------------------------------------------------------'), Sequence(id='sequence117', source_id='XP_003678517.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------------------------SE----------------------HRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK----------------------------------------------------------------------'), Sequence(id='sequence118', source_id='KAG0659075.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSS--------HG--HTSNNNNNNNTPIQASPIAVRSSYNHR----HH-------------'), Sequence(id='sequence119', source_id='XP_451758.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSP-KRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence120', source_id='NP_984991.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPS--------------------E------YTHHGRYRQ--------PEHIRNMAE----------Q--------'), Sequence(id='sequence121', source_id='XP_017989070.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVM-----AASSGYSPTSA------TVEQGQYRQ--------SERAQHTAS----------EQ-------'), Sequence(id='sequence122', source_id='KAG0673910.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence123', source_id='SMN21971.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSE----KNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL-------------------------------------------------------------------------'), Sequence(id='sequence124', source_id='KAG0661436.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN--------------------------------------------------------------------------'), Sequence(id='sequence125', source_id='SCV02624.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MST----NEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSR-TPSPHRSP------------------------------------------------------'), Sequence(id='sequence126', source_id='SCV99388.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSL----ATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS-----------------------------------------------------------------------'), Sequence(id='sequence127', source_id='CUS20182.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----SMV----SGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS----------------------------------------------------------------'), Sequence(id='sequence128', source_id='XP_045933944.1', sequence='-------------------------------------MHFQQ----------------------------------------------------------------------QQQQHYHTPLRHGSDPAQ-HITNNSEEHINN--------YGNNTVDTPQQLRHTS---------AMTVINS---SQAATNNNYSDN---NNNT-SPVRG-----TTS----TAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN--------------------------------------------------------------------------'), Sequence(id='sequence129', source_id='KAA8901327.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPS-----S------PSG-----------GG---------------------------SKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence130', source_id='KAF8417303.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-SSTIA-------------SGSGAGGSYHHQQA------STS-------------SAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence131', source_id='KAF3929277.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RETSP----VSPLRASF--ANLN--------TEDHS---------QATAAIR---AQ---------------AGHTR-HESL--EKYTRR-DSTASE-NRNEEGY----------------------RERGSISSQSGAAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence132', source_id='OEJ86227.1', sequence='------------------------------------MTEYEN----------------------------------------------G----QQQQ---------RERIRGQERESYDEQERESYDEQERERIREQERRINN--------EQQRRVNNEQQ--------------------------RRXNNQQRST---TNDN-VSSNK-----NTH----KDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH-------------------------------------------------------------------------'), Sequence(id='sequence133', source_id='XP_046060918.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS-----------------------------------------------------------------'), Sequence(id='sequence134', source_id='EPS36031.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDASP----VSPLRASF--ANLN--------TDDHT---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRPEEGY----------------------RERGSISSQGGSAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence135', source_id='KAI5807151.1', sequence='--------------------------------------------------------------------------MHELPLAPSLPPPQ----SPPTPDR----------YSQGAARHY---HSNSAAS-A-----PAMIG-----------DA-------AGAYYRGSPPPPMPQQPYVP-R----D-RS-SESYHNGSS--------------------AQQ-QQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence136', source_id='XP_011117899.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RESSP----VSPLRASF--ANLN--------ADDHS---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRNDESY----------------------RDRSSVSSQG-GSG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR----------------------------------------------------------------------------'), Sequence(id='sequence137', source_id='KAI1438264.1', sequence='---------------------------------------MEQDLHTTPGADLE----------P--HGLPDD---GSI---------SSIEDTPEA--------AS--SLNGHETYHQ---HPQSLDYVV-----SSS---------------QNTDETDPNAQYET-VPATSQAQSISR-PPSGLSGAGGDRQAA------------------------HSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence138', source_id='XP_022456167.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV---------------------------------------------------------------------------------'), Sequence(id='sequence139', source_id='KAF3908940.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDVSP----VSPLRASF--ANLN--------TTDDGQS--------ATAAIR---AS---------------AGHTR-HESL--EKYTRR-DSTASE-SRNEDGY----------------------RERSSISSQG-GSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence140', source_id='XP_006693239.1', sequence='---------------------------------------MERDQLAAPAPSE------------------S-----AA---------SDYRDHSLADAEVAPSSDCE--NNGFHDHHY--SQSQHYDQ-------DDAAESE---PT---------------ARYNT-PSGS--GQQISR-PPSGLS-GERGAGYATDQGSRAG------------SNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV---------------------------------------------------------------------------------'), Sequence(id='sequence141', source_id='EWC45326.1', sequence='---------------------------------------MATTPP-------------------------------TK------------RDTSP----VSPLRASF--ANLN--------TTDDGQQ-------SAAAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-SRNDDGY----------------------RERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR----------------------------------------------------------------------------'), Sequence(id='sequence142', source_id='KAF3930522.1', sequence='---------------------------------------MTTTPP-------------------------------TK---------QGSRNVSP----VSPLRASF--ANLN--------TTDENHS-------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSNASE-SKNEDGY----------------------RERSSVSSQGGS--SQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR----------------------------------------------------------------------------'), Sequence(id='sequence143', source_id='KAF8249497.1', sequence='-----------------------------------------------------MQ------Q-HDDDALPQP-QTTELPLAPSLPPPVALAHSPPTPRR----------RNSSPTRHY---HSSSNASGA-----PPYIG-----------SP---GSVESAQYYNSQGSPPTPAAPHQQ-QQFATS-RA-DGGYHNGGG-------------------------YAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence144', source_id='XP_002174495.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence145', source_id='PRP83484.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------MG-----------DQ---NDTE-------------ARIGHSR-LPFFIM-SG-DGEYTG-----------------------------SGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS--------------------------------------------------------------------------------'), Sequence(id='sequence146', source_id='GAA97202.1', sequence='-------------------------------------------------------------------------------------------------------------------------MASSTSTG---------AG-----------SS---SSRQRQESYRSS--------------------------HSQQSS--------------------SQH-APAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI---------------------------------------------------------------------------------'), Sequence(id='sequence147', source_id='OBA26219.1', sequence='------------------------------------MESML-------------------------------------------------------------------------------------QSHNRRR-HTNSMSISG--------SSNNNVHSELRQNNNN---------RISSMPS---SQPASN----------SNN-KPVDN-----IKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR------------------------------------------------------------------------'), Sequence(id='sequence148', source_id='KAI1823332.1', sequence='---------------------------------------MEQDFHAVPAPDSE----------P--HDHPDD---G-L---------GGLEESPDI--------AP--GSNGHELYHQ---HPQSLDYVI-----SNN---------------QNIDDVDPNAPYEA-VATTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence149', source_id='CDO57487.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPS-----IYPNH-KPTGM--------YTGQ-----------------------FISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence150', source_id='KAI2629167.1', sequence='---------------------------------------MDQD--------PM----------A--TPIPHDVHDDTL---------GGIEGSMHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNA---------------HPDEVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence151', source_id='KAI5811198.1', sequence='---------------------------------------MSNDPL----PTIP----------SA-TSSTVD----LS---------NG--NDGSA---QNE---N---EPPHRSQHH--TGM------------TSIHL-----NDPTSQSNAA---ASYSQTHSG-ATMLS-------------SGSGATGSFQQAGG------PSSGGP-----AGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence152', source_id='KAG9017701.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAASGSGAPPAT--------------------PLS-AASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ---------------------------------------------------------------------------------'), Sequence(id='sequence153', source_id='OTA67948.1', sequence='-----------------------------------------------------------------------------------------MHFPGHLP---------DEPSSSSHEPHH--RQSQSLDQGL-----ANSAHP-----------HPHPDDIDPNAQYEA-QQYDPPQQSTQR-PPSSMSS-TGERQY---------------------TEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence154', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVP---A-----------AAAAQVPLPH----------SLSPPLQIDPHDDTL---------SSAGTVSHQ---ALPDHNNFHEHNGYHD------QPQHPIQFQ-----PLDHSVN---NSPRSYYPADQTDSEPTARYAT-PPVA--APAISR-PSSGLSGQGAGYGAD--HVSRAG-----------------SNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence155', source_id='ORX96310.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID---------------------------------------------------------------------------------'), Sequence(id='sequence156', source_id='XP_028477951.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTD-P--------------------------------GYASSG-SGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL---------------------------------------------------------------------------------'), Sequence(id='sequence157', source_id='XP_024666830.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence158', source_id='KAI0099584.1', sequence='-----------------------------------------------------------------------------------------MHIPGHLP---------GES-SSSHEPHH--RQSQSLDQGL-----ANSAP-------------PLPDDIDPNAQYEA-HQYDPPQQPVQR-PASSMSS-TGERQY---------------------NEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence159', source_id='KAI1801530.1', sequence='---------------------------------------------------------------------------------------------MHIA---------GEPGV--HEPHH--RQSRSLDQGL-----ANSAHADDIDTHAVDPHAIDPIAVDHNAQYEA-HSYEPPAQSMSR-PASS--SGTGERHL---------------------NGE--ASREGNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence160', source_id='KAF9351078.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-------------------------TPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence161', source_id='KAF9160900.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATS-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI-----------------------------------------------------------------------'), Sequence(id='sequence162', source_id='KAG0263740.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAGD-------------------------SGKKS--SSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK---------------------------------------------------------------------------------'), Sequence(id='sequence163', source_id='KAI1135662.1', sequence='-----------------------------------------------MEQDPV----------A--APVPHDIHEDTI---------GGIEGSMHIP---------AEPSTSHEPHRH--RQSQSLDRGL-----ASSK---------------HPEDIDPNAQYDT-PQYDPPQQSMPR-PASS-SS-AGERHY---------------------AEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence164', source_id='XP_045969802.1', sequence='---------------------------------------MTTTPP----PLEN----------NGSLPSHID----ID---------VA---------------------ATPRQEHY--TSSSD----------PSLAFSP---QDSNSPSRAN---IGDDQRHSG-TPPLSQSQLY--------GNGGGMNSFTSAAG------AA----------------AGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence165', source_id='KAI1414505.1', sequence='-----------------------------------------------------------------------------------------MHFSGE--------------PSSSHEPLH--RQSQSLDQGL-----ANSAHP-------------HPDDIDPNAQYEA-HQYDPPQQSMQR-PTSSMSS-GGERHY---------------------TEQ--APRESNGT-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence166', source_id='KAG0239750.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATLGD-------------------------SGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence167', source_id='XP_044688071.1', sequence='---------------------------------------MTTTPP----PPEN----------NGSLPSHID----VD---------VA---------------------ATPRQEHY--TS-SD----------PSLTFSP---QDSNSPSRAI-----GDERNSG-TPPLSQSQLY--------GNGGGMNNFTSAAA------------------------AAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence168', source_id='RPB01516.1', sequence='---------------------------------------MTTTPPLLFSPSP-------PPP-LPDSLYPDEPEEVTTPTA-TLPPPP------PSPPP----------RQPSPARHQ---HSGSAPA---------TVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGG-----------------------------GGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence169', source_id='KAG0236582.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-----------------------------SADS--ARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS----------------------------------------------------------------------------------'), Sequence(id='sequence170', source_id='KAH6640987.1', sequence='MEQD-QAIS------PAYAVAPDSALA------------------PARIP--------------SPAGFPTDPHDDTL---------SGVESVTHQ---AVPDHH-IHEHNGFHE------Q-QHISQLQ-----PLDHNVT---NSPRSPYPTDTTDSEPTARYAT-PPIQ--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence171', source_id='XP_002493958.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSPR-------------------RNQHRRS----------------------HSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI---------------------------------------------------------------------------------'), Sequence(id='sequence172', source_id='KAA8914877.1', sequence='---------------------------------------MTTTPPPSRTSTSDMDHSARTPS-SSSSSIPEEYIHTELRLAPS----LSSLQSPPTPDR----------GSPSRYHHS---HSNSATSAP----------------------------SDGASYYGGSPPA-MRDRD-RE-GYYGNGAGA-AGGSGGGAG--------------------SSA-YNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence173', source_id='XP_018701974.1', sequence='---------------------------------------METDDV--PAATLH----------D-----NLD----DT---------LG----GLDGSPQVPSSSHY--SNHHHDHQY--QNPHHSNN-------DTHEHEP---QSPG-GGPSH---HQ-QQHHDE-DPPC--TRY-TP-PAPGSS-APASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence174', source_id='KAI2643608.1', sequence='---------------------------------------MEHDLHGAPVSGLE----------P--HAHHDD---DSL---------NDADEHSDI--------AS--SLNGHESYHQ---PSQSLDYVL-----SHG---------------QDTDEADPNSQYET-QPTTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence175', source_id='KAG0125076.1', sequence='---------------------------------------MTTTPPPLFSPSP-------PPP-LPDSLCPDDPEEVTTPTS-NLPPPP-----LPSPPP----------RQPSPVRHH---HSGPAPA---------AVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGS-----------------------------GGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence176', source_id='KAH9904989.1', sequence='---------------------------------------MEQDPV--------------------AAAVPQDGYDDTLG---------GIEGSPHVGPT----------QINREKRHQ---QSQSLDNGL-----P-NNG-----------HA---DEIDPNARYDTPPN-PLQPHSISR-PPSGLS-GAGDRHNAYSDH--------------------ASR-GSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence177', source_id='VEU24358.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------MDNRSVSTRIPRSHSTSEALSEEPARSVSSTV--DGYDNYY-----------GHQH---HHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence178', source_id='KAI1283572.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--EPLPDTF---------ADVEGGPHV--------SP--SQNGHEVYHHHHQQSQSLDHGL-----ASS---------------QNHDEADLNGRYET-PPSTAHPQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence179', source_id='KAI1500557.1', sequence='--------------------------------------MMEHDPAFATAPGPH----------N-----GIDD--------------------MLGGIEGSPTLASG--QNGHETYHH--HHSQSFDQ-------E----IP---LN---ENPDD---MDTTAQYDT-PPVTAQPQSISR-PPSALD-GAAGER-----------------------HASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence180', source_id='KAI2623093.1', sequence='---------------------------------------MDQDPITTPVQAPA----------Q--DPTPHELHEDTF---------GGIEGSMHLS---------GEPGT--PEAHH--RQSQSLDQGL-----ANSV---------------HPDEVDPNTQYEA-HQYDAPPQSMPR-PASSMSG-AGERQY---------------------PEH--ASRESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence181', source_id='NP_593285.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR---------------------------------------------------------------------------------'), Sequence(id='sequence182', source_id='KAI0431960.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--ETLPDTL---------ADVEGAPHV--------SP--SQNGHEVYHHH-QQSHSLDQGL-----ANS---------------QTSDEPDLNGRYET-PPSTGHAQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence183', source_id='KAH8926511.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSAGP-----LALE-----KGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV---------------------------------------------------------------------------------'), Sequence(id='sequence184', source_id='RMJ24013.1', sequence='-----------------------------------------MNPS-------------------------------YH---------NGYSSDSHA--QYSTGPAGF--NPPVHDS-----TSQDAEQ-------TRLTFSP---SI---------------TQQPQ-PPSL---SRPS---SAFSS-GPERHG-------------------------ASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV---------------------------------------------------------------------------------'), Sequence(id='sequence185', source_id='KAF8931046.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATG-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN---------------------------------------------------------------------------------'), Sequence(id='sequence186', source_id='ODQ76250.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS------AA----------------PNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV---------------------------------------------------------------------------------'), Sequence(id='sequence187', source_id='KXJ93426.1', sequence='---------------------------------------MDQEPAAL------------PPTRNPLDVAPDD----TL---------GGIESSPRVYSD----------PESTIRTHH---HSQSLDQGL-----ASSAH-----------YQHNSEDMD-HQTRQDTPPIPQQPQSISR-PPSGLSGAGDRQPAQYSDH--------------------ASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence188', source_id='XP_051368163.1', sequence='---------------------------------------MDQDLLG-----------------T--PTAPHDTLDDAL---------AGVEGPLHLA---------SESGN--LEPHH--RQSQSLDRGL-----ANNAQVDDF---------------DTAVPFDS-PQYDTPPPAMQR-PASSD-SAAGEKQL---------------------AEH--ASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence189', source_id='GES63634.1', sequence='-------METIHNL--NTGV-SEPVEQQP------QESAFEASPVSHPAGSTD----------E-----PTSASVYHR---------SGYNSDSHA--QYSSLA----------------------------------------------------------THQPQ-PP------TSSR-PSSGLS-GPERYGP----------------------SQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV---------------------------------------------------------------------------------'), Sequence(id='sequence190', source_id='RPA74746.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------M---------------ADHHE-GSSH---SYDR---TSHSS-RP-------------------------------ATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence191', source_id='XP_024675402.1', sequence='-------MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPA-GPYPSHV----------ESVPPEVIPSASTYH---------AGYSSDSHAN--YSSNAVDF--NS--------------------------GSEYP---PQPRAELPRA---QEAVPSMMH-PPAA---PSSSR-PSSGLSSGPDRL-----------------------GSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL---------------------------------------------------------------------------------'), Sequence(id='sequence192', source_id='KAH6850716.1', sequence='MEQE-QAFN------PAYTMAPDPALA------------------PAPIPAPI----------SSPVGLPTDPHDDTL---------SGVESVTHQ---ALPDHN-IHDHNGFHE------Q-QHLVQLQ-----PLDHSVN---NSPRSPYPTDTTDSEPTARYAT-PPIP--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence193', source_id='PHH71636.1', sequence='---------------------------------------MEHQQPE-LDQ--Q----------PPPLHAAHDSLDDTL---------GGIEGSPHVAA----------ANNGFHQ------QSQSLDSAV-----P---------NSPR--------YDDDAANRHT-P-PVSSAPSLSR-PGSQMS-----------------NPSSSNPPQQMHG----NDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence194', source_id='KAJ3562589.1', sequence='------------------------------------MDTMEQDLHTTPIPGVH----------E--HHHLDDALPDPH---------ADVDARPHS--------AP--GQNGHEVYH---QQSHSLDQGI-----AHG---------------QHPDEADLNGRYDT-PPSATHPQSISR-PPSGLSGAGGDRQTT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV--------------------------------------------------------------------------------'), Sequence(id='sequence195', source_id='RDA84390.1', sequence='---------------------------------------MDHQPAA-DQEQPQ----------ELPRPASHDGLDDTL---------GGIEGSPHPVA----------SSNGFHA------HQ-----EA-----P---------GSPR--------YDDDNAARQT-P-PVSA--PLSR-PGSQMS-----------------N-----PPQHASG----SDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence196', source_id='XP_007413704.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNMTSSTGP-----AGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV---------------------------------------------------------------------------------'), Sequence(id='sequence197', source_id='KAI0376630.1', sequence='---------------------------------------------------------------------------------------------MHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNV---------------HPDDVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence198', source_id='XP_047831721.1', sequence='---------------------------------------MEQDFHTAPIPGPR----------E--HLDALPDTHDTH---------ADVVARPHT--------AP--DQNGHEVYH---QQSQSLDQGL-----SDS---------------QHHDDADVAGRYET-HPSTTHPQSISR-PPSGLSGAGGDRQAT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence199', source_id='KAI9294962.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE-------------------------------------------------------------------------------')], standard_numberings=[StandardNumbering(id='standardnumbering0', reference_id='BAH60832.1', numbered_id='CAI4663910.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', 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'69.274', '70.275', '71.276', '72.277', '73.278', '74.279', '75.280', '76.281', '77.282', '78.283', '79.284', '80.285', '81.286', '82.287', '83.288', '84.289', '85.290', '86.291', '87.292', '88.293', '89.294', '90.295', '91.296', '92.297', '93.298', '94.299', '95.300', '96.301', '97.302', '98.303', '99.304', '100.305', '101.306', '102.307', '103.308', '104.309', '105.310', '106.311', '107.312', '108.313', '109.314', '110.315', '111.316', '112.317', '113.318', '114.319', '115.320', '116.321', '117.322', '118.323', '119.324', '120.325', '121.326', '122.327', '123.328', '124.329', '125.330', '126.331', '127.332', '128.333', '129.334', '130.335', '131.336', '132.337', '133.338', '134.339', '135.340', '136.341', '137.342', '138.343', '139.344', '140.345', '141.346', '142.347', '143.348', '144.349', '145.350', '146.351', '147.352', '148.353', '149.354', '150.355', '151.356', '152.357', '153.358', '154.359', '155.360', '156.361', '157.362', '158.363', '159.364', '160.365', '161.366', '162.367', '163.368', '164.369', '165.370', '166.371', '167.372', '168.373', '169.374', '170.375', '171.376', '172.377', '173.378', '174.379', '175.380', '176.381', '177.382', '178.383', '179.384', '180.385', '181.386', '182.387', '183.388', '184.389', '185.390', '186.391', '187.392', '188.393', '189.394', '190.395', '191.396', '192.397', '193.398', '194.399', '195.400', '196.401', '197.402', '198.403', '199.404', '200.405', '201.406', '202.407', '203.408', '204.409', '205.410', '206.411', '207.412', '208.413', '209.414', '210.415', '211.416', '212.417', '213.418', '214.419', '215.420', '216.421', '217', '218', '219', '220', '221', '222', '223', '224', '225', '226', '227', '228', '229', '230', '231', '232', '233', '234', '235', '236', '237', '237.422', '238', '239', '240', '241', '242', '243', '243.423', '243.424', '243.425', '243.426', '243.427', '243.428', '243.429', '243.430', '243.431', '244', '245', '246', '247', '248', '249', '250', '251', '252', '253', '254', '254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454', '254.455', '254.456', '254.457', '254.458', '254.459', '254.460', '254.461', '254.462', '254.463', '254.464']), StandardNumbering(id='standardnumbering98', reference_id='BAH60832.1', numbered_id='KAI9294962.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', '0.45', '0.46', '0.47', '0.48', '0.49', '0.50', '0.51', '0.52', '0.53', '0.54', '0.55', '0.56', '0.57', '0.58', '0.59', '0.60', '0.61', '0.62', '0.63', '0.64', '0.65', '0.66', '0.67', '0.68', '0.69', '0.70', '0.71', '0.72', '0.73', '0.74', '0.75', '0.76', '0.77', '0.78', '0.79', '0.80', '0.81', '0.82', '0.83', '0.84', '0.85', '0.86', '0.87', '0.88', '0.89', '0.90', '0.91', '0.92', '0.93', '0.94', '0.95', '0.96', '0.97', '0.98', '0.99', '0.100', '0.101', '0.102', '0.103', '0.104', '0.105', '0.106', '0.107', '0.108', '0.109', '0.110', '0.111', '0.112', '0.113', '0.114', '0.115', '0.116', '0.117', '0.118', '0.119', '0.120', '0.121', '0.122', '0.123', '0.124', '0.125', '0.126', '0.127', '0.128', '0.129', '0.130', '0.131', '0.132', '0.133', '0.134', '0.135', '0.136', '0.137', '0.138', '0.139', '0.140', '0.141', '0.142', '0.143', '0.144', '0.145', '0.146', '0.147', '0.148', '0.149', '0.150', '0.151', '0.152', '0.153', '0.154', '0.155', '0.156', '0.157', '0.158', '0.159', '0.160', '0.161', '0.162', '0.163', '0.164', '0.165', '0.166', '0.167', '0.168', '0.169', '0.170', '0.171', '0.172', '0.173', '0.174', '0.175', '0.176', '0.177', '0.178', '0.179', '0.180', '1', '2', '3', '3.181', '3.182', '3.183', '3.184', '3.185', '3.186', '3.187', '3.188', '3.189', '3.190', '3.191', '3.192', '4', '5', '5.193', '5.194', '5.195', '5.196', '5.197', '6', '7', '7.198', '7.199', '7.200', '7.201', '7.202', '8', '8.203', '8.204', '8.205', '8.206', '8.207', '8.208', '8.209', '8.210', '8.211', '9', '10', '11', '12', '13', '14', '15', '16', '17', '18', '19.212', '20.213', '21.214', '22.215', '23.216', '24.217', '25.218', '26.219', '27.220', '28.221', '29.222', '30.223', '31.224', '32.225', '33.226', '34.227', '35.228', '36.229', '37.230', '38.231', '39.232', '40.233', '41.234', '42.235', '43.236', '44.237', '45.238', '46.239', '47.240', '48.241', '49.242', '50.243', '51.244', '52.245', '53.246', '54.247', '55.248', '56.249', '57.250', '58.251', '59.252', '60.253', '61.254', '62.255', '63.256', '64.257', '65.258', '66.259', '67.260', '68.261', '69.262', '70.263', '71.264', '72.265', '73.266', '74.267', '75.268', '76.269', '77.270', '78.271', '79.272', '80.273', '81.274', '82.275', '83.276', '84.277', '85.278', '86.279', '87.280', '88.281', '89.282', '90.283', '91.284', '92.285', '93.286', '94.287', '95.288', '96.289', '97.290', '98.291', '99.292', '100.293', '101.294', '102.295', '103.296', '104.297', '105.298', '106.299', '107.300', '108.301', '109.302', '110.303', '111.304', '112.305', '113.306', '114.307', '115.308', '116.309', '117.310', '118.311', '119.312', '120.313', '121.314', '122.315', '123.316', '124.317', '125.318', '126.319', '127.320', '128.321', '129.322', '130.323', '131.324', '132.325', '133.326', '134.327', '135.328', '136.329', '137.330', '138.331', '139.332', '140.333', '141.334', '142.335', '143.336', '144.337', '145.338', '146.339', '147.340', '148.341', '149.342', '150.343', '151.344', '152.345', '153.346', '154.347', '155.348', '156.349', '157.350', '158.351', '159.352', '160.353', '161.354', '162.355', '163.356', '164.357', '165.358', '166.359', '167.360', '168.361', '169.362', '170.363', '171.364', '172.365', '173.366', '174.367', '175.368', '176.369', '177.370', '178.371', '179.372', '180.373', '181.374', '182.375', '183.376', '184.377', '185.378', '186.379', '187.380', '188.381', '189.382', '190.383', '191.384', '192.385', '193.386', '194.387', '195.388', '196.389', '197.390', '198.391', '199.392', '200.393', '201.394', '202.395', '203.396', '204.397', '205.398', '206.399', '207.400', '208.401', '209.402', '210.403', '211.404', '212.405', '213.406', '214.407', '215.408', '216.409', '217.410', '218.411', '219', '220', '221', '222', '223', '224', '225', '226', '227', '228', '229', '230', '231', '232', '233', '234', '235', '236', '237', '237.412', '238', '239', '240', '241', '242', '243', '243.413', '243.414', '243.415', '243.416', '243.417', '243.418', '243.419', '243.420', '243.421', '244', '245', '246', '247', '248', '249', '250', '251', '252', '253', '254', '254.422', '254.423', '254.424', '254.425', '254.426', '254.427', '254.428', '254.429', '254.430', '254.431', '254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454'])])"
- ]
- },
- "execution_count": 4,
- "metadata": {},
- "output_type": "execute_result"
- }
- ],
- "source": [
- "alignment = Alignment.from_sequences(blast_results)\n",
- "alignment.align(ClustalOmega)"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 5,
- "metadata": {},
- "outputs": [],
- "source": [
- "alignment.apply_standard_numbering()"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 15,
- "metadata": {},
- "outputs": [
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 41.51it/s]\n"
- ]
- },
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "🏃 Running CLUSTALO\n"
- ]
- }
- ],
- "source": [
- "# Get sequences\n",
- "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\", \"AAT46414.1\", \"AAT46415.1\"]\n",
- "sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
- "\n",
- "# Create and run alignment\n",
- "alignment = Alignment.from_sequences(blast_results, aligner=ClustalOmega)"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 14,
- "metadata": {},
- "outputs": [
- {
- "data": {
- "text/plain": [
- "Alignment(id='alignment4', method='CLUSTALO', consensus='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', input_sequences=[Sequence(id='sequence228', source_id='BAH60832.1', sequence='MSASEMRAASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDNENKELVSQPHNYGHTSE'), Sequence(id='sequence229', source_id='CAI4663910.1', sequence='MATPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQDRKSHNIRKPSSSPSSKAPSPGVNT'), Sequence(id='sequence230', source_id='EJT44931.1', sequence='MTTPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQDRKNHTVKKPSSSPSSKPPSPGVNI'), Sequence(id='sequence231', source_id='XP_037139093.1', sequence='MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRPSPSARTSFS'), Sequence(id='sequence232', source_id='XP_003680887.1', sequence='MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRSSPSTRSSTS'), Sequence(id='sequence233', source_id='XP_037144827.1', sequence='MSQEYRTRSRSRSFSDQAATQEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIKNSNTNVTTESRRKSPTYTQ'), Sequence(id='sequence234', source_id='AQZ18344.1', sequence='MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG'), Sequence(id='sequence235', source_id='XP_002495560.1', sequence='MDNSDQEVQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR'), Sequence(id='sequence236', source_id='XP_003673548.1', sequence='MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS'), Sequence(id='sequence237', source_id='XP_003958955.1', sequence='MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLKTPRA'), Sequence(id='sequence238', source_id='XP_001644471.1', sequence='MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASASSSASSPSAST'), Sequence(id='sequence239', source_id='XP_003684279.1', sequence='MPYRENRNASSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence240', source_id='SMN18735.1', sequence='MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSSSISPPKSKGTTAS'), Sequence(id='sequence241', source_id='CAD1779387.1', sequence='MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTSSTSTSQVKAKETTAT'), Sequence(id='sequence242', source_id='KAG0666170.1', sequence='MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS'), Sequence(id='sequence243', source_id='XP_022464898.1', sequence='MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERTPVSSQQ'), Sequence(id='sequence244', source_id='XP_003669861.1', sequence='MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK'), Sequence(id='sequence245', source_id='XP_003678517.1', sequence='MASEHRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK'), Sequence(id='sequence246', source_id='KAG0659075.1', sequence='MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSSHGHTSNNNNNNNTPIQASPIAVRSSYNHRHH'), Sequence(id='sequence247', source_id='XP_451758.1', sequence='MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSPKRQVHTPPPSS'), Sequence(id='sequence248', source_id='NP_984991.1', sequence='MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPSEYTHHGRYRQPEHIRNMAEQ'), Sequence(id='sequence249', source_id='XP_017989070.1', sequence='MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVMAASSGYSPTSATVEQGQYRQSERAQHTASEQ'), Sequence(id='sequence250', source_id='KAG0673910.1', sequence='MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVHTPPPSS'), Sequence(id='sequence251', source_id='SMN21971.1', sequence='MNSEKNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL'), Sequence(id='sequence252', source_id='KAG0661436.1', sequence='MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN'), Sequence(id='sequence253', source_id='SCV02624.1', sequence='MSTNEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSRTPSPHRSP'), Sequence(id='sequence254', source_id='SCV99388.1', sequence='MSLATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS'), Sequence(id='sequence255', source_id='CUS20182.1', sequence='MSMVSGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS'), Sequence(id='sequence256', source_id='XP_045933944.1', sequence='MHFQQQQQQHYHTPLRHGSDPAQHITNNSEEHINNYGNNTVDTPQQLRHTSAMTVINSSQAATNNNYSDNNNNTSPVRGTTSTAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN'), Sequence(id='sequence257', source_id='KAA8901327.1', sequence='MSTPSSPSGGGSKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW'), Sequence(id='sequence258', source_id='KAF8417303.1', sequence='MSDSSTIASGSGAGGSYHHQQASTSSAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV'), Sequence(id='sequence259', source_id='KAF3929277.1', sequence='MTTTPPTKRETSPVSPLRASFANLNTEDHSQATAAIRAQAGHTRHESLEKYTRRDSTASENRNEEGYRERGSISSQSGAAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence260', source_id='OEJ86227.1', sequence='MTEYENGQQQQRERIRGQERESYDEQERESYDEQERERIREQERRINNEQQRRVNNEQQRRXNNQQRSTTNDNVSSNKNTHKDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH'), Sequence(id='sequence261', source_id='XP_046060918.1', sequence='MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS'), Sequence(id='sequence262', source_id='EPS36031.1', sequence='MTTTPPTKRDASPVSPLRASFANLNTDDHTSATAAIRAAAGHTRHESLEKYTRRDSTASENRPEEGYRERGSISSQGGSAGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR'), Sequence(id='sequence263', source_id='KAI5807151.1', sequence='MHELPLAPSLPPPQSPPTPDRYSQGAARHYHSNSAASAPAMIGDAAGAYYRGSPPPPMPQQPYVPRDRSSESYHNGSSAQQQQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence264', source_id='XP_011117899.1', sequence='MTTTPPTKRESSPVSPLRASFANLNADDHSSATAAIRAAAGHTRHESLEKYTRRDSTASENRNDESYRDRSSVSSQGGSGAKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR'), Sequence(id='sequence265', source_id='KAI1438264.1', sequence='MEQDLHTTPGADLEPHGLPDDGSISSIEDTPEAASSLNGHETYHQHPQSLDYVVSSSQNTDETDPNAQYETVPATSQAQSISRPPSGLSGAGGDRQAAHSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence266', source_id='XP_022456167.1', sequence='MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV'), Sequence(id='sequence267', source_id='KAF3908940.1', sequence='MTTTPPTKRDVSPVSPLRASFANLNTTDDGQSATAAIRASAGHTRHESLEKYTRRDSTASESRNEDGYRERSSISSQGGSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR'), Sequence(id='sequence268', source_id='XP_006693239.1', sequence='MERDQLAAPAPSESAASDYRDHSLADAEVAPSSDCENNGFHDHHYSQSQHYDQDDAAESEPTARYNTPSGSGQQISRPPSGLSGERGAGYATDQGSRAGSNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV'), Sequence(id='sequence269', source_id='EWC45326.1', sequence='MATTPPTKRDTSPVSPLRASFANLNTTDDGQQSAAAAIRAAAGHTRHESLEKYTRRDSTASESRNDDGYRERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR'), Sequence(id='sequence270', source_id='KAF3930522.1', sequence='MTTTPPTKQGSRNVSPVSPLRASFANLNTTDENHSSATAAIRAAAGHTRHESLEKYTRRDSNASESKNEDGYRERSSVSSQGGSSQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR'), Sequence(id='sequence271', source_id='KAF8249497.1', sequence='MQQHDDDALPQPQTTELPLAPSLPPPVALAHSPPTPRRRNSSPTRHYHSSSNASGAPPYIGSPGSVESAQYYNSQGSPPTPAAPHQQQQFATSRADGGYHNGGGYAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV'), Sequence(id='sequence272', source_id='XP_002174495.1', sequence='MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV'), Sequence(id='sequence273', source_id='PRP83484.1', sequence='MGDQNDTEARIGHSRLPFFIMSGDGEYTGSGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS'), Sequence(id='sequence274', source_id='GAA97202.1', sequence='MASSTSTGAGSSSSRQRQESYRSSHSQQSSSQHAPAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI'), Sequence(id='sequence275', source_id='OBA26219.1', sequence='MESMLQSHNRRRHTNSMSISGSSNNNVHSELRQNNNNRISSMPSSQPASNSNNKPVDNIKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR'), Sequence(id='sequence276', source_id='KAI1823332.1', sequence='MEQDFHAVPAPDSEPHDHPDDGLGGLEESPDIAPGSNGHELYHQHPQSLDYVISNNQNIDDVDPNAPYEAVATTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence277', source_id='CDO57487.1', sequence='MSIPSIYPNHKPTGMYTGQFISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW'), Sequence(id='sequence278', source_id='KAI2629167.1', sequence='MDQDPMATPIPHDVHDDTLGGIEGSMHLPNEPHNHETHHRQSQSLDQGLANNAHPDEVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence279', source_id='KAI5811198.1', sequence='MSNDPLPTIPSATSSTVDLSNGNDGSAQNENEPPHRSQHHTGMTSIHLNDPTSQSNAAASYSQTHSGATMLSSGSGATGSFQQAGGPSSGGPAGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV'), Sequence(id='sequence280', source_id='KAG9017701.1', sequence='MSTAASGSGAPPATPLSAASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ'), Sequence(id='sequence281', source_id='OTA67948.1', sequence='MHFPGHLPDEPSSSSHEPHHRQSQSLDQGLANSAHPHPHPDDIDPNAQYEAQQYDPPQQSTQRPPSSMSSTGERQYTEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence282', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVPAAAAAQVPLPHSLSPPLQIDPHDDTLSSAGTVSHQALPDHNNFHEHNGYHDQPQHPIQFQPLDHSVNNSPRSYYPADQTDSEPTARYATPPVAAPAISRPSSGLSGQGAGYGADHVSRAGSNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence283', source_id='ORX96310.1', sequence='MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID'), Sequence(id='sequence284', source_id='XP_028477951.1', sequence='MTDPGYASSGSGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL'), Sequence(id='sequence285', source_id='XP_024666830.1', sequence='MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW'), Sequence(id='sequence286', source_id='KAI0099584.1', sequence='MHIPGHLPGESSSSHEPHHRQSQSLDQGLANSAPPLPDDIDPNAQYEAHQYDPPQQPVQRPASSMSSTGERQYNEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence287', source_id='KAI1801530.1', sequence='MHIAGEPGVHEPHHRQSRSLDQGLANSAHADDIDTHAVDPHAIDPIAVDHNAQYEAHSYEPPAQSMSRPASSSGTGERHLNGEASREGNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence288', source_id='KAF9351078.1', sequence='MSDTPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY'), Sequence(id='sequence289', source_id='KAF9160900.1', sequence='MAATSESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI'), Sequence(id='sequence290', source_id='KAG0263740.1', sequence='MAAAGDSGKKSSSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK'), Sequence(id='sequence291', source_id='KAI1135662.1', sequence='MEQDPVAAPVPHDIHEDTIGGIEGSMHIPAEPSTSHEPHRHRQSQSLDRGLASSKHPEDIDPNAQYDTPQYDPPQQSMPRPASSSSAGERHYAEQASRESNGADRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence292', source_id='XP_045969802.1', sequence='MTTTPPPLENNGSLPSHIDIDVAATPRQEHYTSSSDPSLAFSPQDSNSPSRANIGDDQRHSGTPPLSQSQLYGNGGGMNSFTSAAGAAAGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence293', source_id='KAI1414505.1', sequence='MHFSGEPSSSHEPLHRQSQSLDQGLANSAHPHPDDIDPNAQYEAHQYDPPQQSMQRPTSSMSSGGERHYTEQAPRESNGTDRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence294', source_id='KAG0239750.1', sequence='MATLGDSGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY'), Sequence(id='sequence295', source_id='XP_044688071.1', sequence='MTTTPPPPENNGSLPSHIDVDVAATPRQEHYTSSDPSLTFSPQDSNSPSRAIGDERNSGTPPLSQSQLYGNGGGMNNFTSAAAAAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM'), Sequence(id='sequence296', source_id='RPB01516.1', sequence='MTTTPPLLFSPSPPPPLPDSLYPDEPEEVTTPTATLPPPPPSPPPRQPSPARHQHSGSAPATVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGGGGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence297', source_id='KAG0236582.1', sequence='MAASADSARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS'), Sequence(id='sequence298', source_id='KAH6640987.1', sequence='MEQDQAISPAYAVAPDSALAPARIPSPAGFPTDPHDDTLSGVESVTHQAVPDHHIHEHNGFHEQQHISQLQPLDHNVTNSPRSPYPTDTTDSEPTARYATPPIQAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence299', source_id='XP_002493958.1', sequence='MPDSPRRNQHRRSHSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI'), Sequence(id='sequence300', source_id='KAA8914877.1', sequence='MTTTPPPSRTSTSDMDHSARTPSSSSSSIPEEYIHTELRLAPSLSSLQSPPTPDRGSPSRYHHSHSNSATSAPSDGASYYGGSPPAMRDRDREGYYGNGAGAAGGSGGGAGSSAYNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV'), Sequence(id='sequence301', source_id='XP_018701974.1', sequence='METDDVPAATLHDNLDDTLGGLDGSPQVPSSSHYSNHHHDHQYQNPHHSNNDTHEHEPQSPGGGPSHHQQQHHDEDPPCTRYTPPAPGSSAPASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence302', source_id='KAI2643608.1', sequence='MEHDLHGAPVSGLEPHAHHDDDSLNDADEHSDIASSLNGHESYHQPSQSLDYVLSHGQDTDEADPNSQYETQPTTSQPQSISRPPSGLSGAGGDRQTAHSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence303', source_id='KAG0125076.1', sequence='MTTTPPPLFSPSPPPPLPDSLCPDDPEEVTTPTSNLPPPPLPSPPPRQPSPVRHHHSGPAPAAVGNFGSPPPNPPPPPQSLAYQQNGAGTTPTQAHYGSGGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV'), Sequence(id='sequence304', source_id='KAH9904989.1', sequence='MEQDPVAAAVPQDGYDDTLGGIEGSPHVGPTQINREKRHQQSQSLDNGLPNNGHADEIDPNARYDTPPNPLQPHSISRPPSGLSGAGDRHNAYSDHASRGSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence305', source_id='VEU24358.1', sequence='MDNRSVSTRIPRSHSTSEALSEEPARSVSSTVDGYDNYYGHQHHHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV'), Sequence(id='sequence306', source_id='KAI1283572.1', sequence='MDTMEQDFHAAPIPGPHEHLDEPLPDTFADVEGGPHVSPSQNGHEVYHHHHQQSQSLDHGLASSQNHDEADLNGRYETPPSTAHPQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence307', source_id='KAI1500557.1', sequence='MMEHDPAFATAPGPHNGIDDMLGGIEGSPTLASGQNGHETYHHHHSQSFDQEIPLNENPDDMDTTAQYDTPPVTAQPQSISRPPSALDGAAGERHASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC'), Sequence(id='sequence308', source_id='KAI2623093.1', sequence='MDQDPITTPVQAPAQDPTPHELHEDTFGGIEGSMHLSGEPGTPEAHHRQSQSLDQGLANSVHPDEVDPNTQYEAHQYDAPPQSMPRPASSMSGAGERQYPEHASRESNGADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence309', source_id='NP_593285.1', sequence='MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR'), Sequence(id='sequence310', source_id='KAI0431960.1', sequence='MDTMEQDFHAAPIPGPHEHLDETLPDTLADVEGAPHVSPSQNGHEVYHHHQQSHSLDQGLANSQTSDEPDLNGRYETPPSTGHAQSISRPPSGLSGGDRQTAYSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence311', source_id='KAH8926511.1', sequence='MSDSAGPLALEKGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV'), Sequence(id='sequence312', source_id='RMJ24013.1', sequence='MNPSYHNGYSSDSHAQYSTGPAGFNPPVHDSTSQDAEQTRLTFSPSITQQPQPPSLSRPSSAFSSGPERHGASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV'), Sequence(id='sequence313', source_id='KAF8931046.1', sequence='MAATGESAKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN'), Sequence(id='sequence314', source_id='ODQ76250.1', sequence='MSSAAPNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV'), Sequence(id='sequence315', source_id='KXJ93426.1', sequence='MDQEPAALPPTRNPLDVAPDDTLGGIESSPRVYSDPESTIRTHHHSQSLDQGLASSAHYQHNSEDMDHQTRQDTPPIPQQPQSISRPPSGLSGAGDRQPAQYSDHASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence316', source_id='XP_051368163.1', sequence='MDQDLLGTPTAPHDTLDDALAGVEGPLHLASESGNLEPHHRQSQSLDRGLANNAQVDDFDTAVPFDSPQYDTPPPAMQRPASSDSAAGEKQLAEHASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence317', source_id='GES63634.1', sequence='METIHNLNTGVSEPVEQQPQESAFEASPVSHPAGSTDEPTSASVYHRSGYNSDSHAQYSSLATHQPQPPTSSRPSSGLSGPERYGPSQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV'), Sequence(id='sequence318', source_id='RPA74746.1', sequence='MADHHEGSSHSYDRTSHSSRPATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV'), Sequence(id='sequence319', source_id='XP_024675402.1', sequence='MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPAGPYPSHVESVPPEVIPSASTYHAGYSSDSHANYSSNAVDFNSGSEYPPQPRAELPRAQEAVPSMMHPPAAPSSSRPSSGLSSGPDRLGSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL'), Sequence(id='sequence320', source_id='KAH6850716.1', sequence='MEQEQAFNPAYTMAPDPALAPAPIPAPISSPVGLPTDPHDDTLSGVESVTHQALPDHNIHDHNGFHEQQHLVQLQPLDHSVNNSPRSPYPTDTTDSEPTARYATPPIPAPTISRPPSGLSGQGAAYGADQVSRAGSNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC'), Sequence(id='sequence321', source_id='PHH71636.1', sequence='MEHQQPELDQQPPPLHAAHDSLDDTLGGIEGSPHVAAANNGFHQQSQSLDSAVPNSPRYDDDAANRHTPPVSSAPSLSRPGSQMSNPSSSNPPQQMHGNDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence322', source_id='KAJ3562589.1', sequence='MDTMEQDLHTTPIPGVHEHHHLDDALPDPHADVDARPHSAPGQNGHEVYHQQSHSLDQGIAHGQHPDEADLNGRYDTPPSATHPQSISRPPSGLSGAGGDRQTTYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV'), Sequence(id='sequence323', source_id='RDA84390.1', sequence='MDHQPAADQEQPQELPRPASHDGLDDTLGGIEGSPHPVASSNGFHAHQEAPGSPRYDDDNAARQTPPVSAPLSRPGSQMSNPPQHASGSDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV'), Sequence(id='sequence324', source_id='XP_007413704.1', sequence='MSNMTSSTGPAGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV'), Sequence(id='sequence325', source_id='KAI0376630.1', sequence='MHLPNEPHNHETHHRQSQSLDQGLANNVHPDDVDPNAQYEAHQYDQPSQSVPRPASSMSSTGGERQYSDQAARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV'), Sequence(id='sequence326', source_id='XP_047831721.1', sequence='MEQDFHTAPIPGPREHLDALPDTHDTHADVVARPHTAPDQNGHEVYHQQSQSLDQGLSDSQHHDDADVAGRYETHPSTTHPQSISRPPSGLSGAGGDRQATYSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC'), Sequence(id='sequence327', source_id='KAI9294962.1', sequence='MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE')], aligned_sequences=[Sequence(id='sequence328', source_id='BAH60832.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSA------------SE-----MR-----A---------ASERVGEERNSLPSVRNQVDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIATLGSSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYNLFIDLEEEYQEKVSKTSMKYAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDLTLTIPEINEIGDPLLIYKELGSKKNKSKNSSKPRRRSPVDN-ENKELV---------SQPHNYGHTSE---------------------------------'), Sequence(id='sequence329', source_id='CAI4663910.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------A-TPSTGANNSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQADGLNDSAIPILVGTKYDLLIDLDPEYQEQISRTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGGQQHRHHNKSQD--RKSHNIRKPSS-------------------SPSSKAPSPGVNT-----------------------'), Sequence(id='sequence330', source_id='EJT44931.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---------T-TPITGGSTSIPAVRNQVEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIATVGSSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLIDLDPEYQEQISGTSMKYAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKHLGSQQRRRQSKSQD--RKNHTVKKPSS-------------------SPSSKPPSPGVNI-----------------------'), Sequence(id='sequence331', source_id='XP_037139093.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSGGTDVQAQQELPKVKSRVDVQVGLVGDAQVGKTSLIVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLVFCSTAKSVNVQKIFKIALAKIFNLTLTIPEINEIGDPLLIYKSLGNHRARGEEISRRP--SPSARTSFS--------------------------------------------------------'), Sequence(id='sequence332', source_id='XP_003680887.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEAQEQQELPKAKNRVDVQVGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSLMDLGGQREFINMLPIASLGSSAIVFLFDLTRPETLSSIKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPEYQEQLSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKIALAKIFKLTLTVQEINDVGDPLLIYRHLGNQRHDSDEVSRRS--SPSTRSSTS--------------------------------------------------------'), Sequence(id='sequence333', source_id='XP_037144827.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MSQEYR----T---------RSRSRSF------------SD-----QA-----AT-----QEEERPFVNLNMNVNMRPKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSVRSTDIVFSLMDLGGQREFINMLPIASLGSSAIIFLFDLTRAETLSSIKEWFRQAHGLNDTAIPILVGTKYDLFVDLDPDYQEQMSRTSMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTIQEINEVGDPLLIYKTLGTAKRDQDKTDNIK--NSNTNVTTES-----------------------RRKSPTYTQ-----------------------'), Sequence(id='sequence334', source_id='AQZ18344.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGSQETQGQQTMNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIVFSIMDLGGQREFINMLPIASLGSSAMVFLFDLTRPDTLTSVKEWYRQAHGLNETAVPLLVGTKYDLFVDLDPAYQEQLSRTSMEYAQVMDAPLVFCSTAKSINVQKIFKIALAKIFHLTLTLPEINEIGDPLLIYSTLGNKRSRRAARG----------------------------------------------------------------------'), Sequence(id='sequence335', source_id='XP_002495560.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDN------------SD-----QE-------------VQGHQHQQQQQPTNVKVKNQVEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRSTDIIFSIMDLGGQREFINMLPIASLGSSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFVDLDPVYQEQLSRASMEYAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSLTLTVPEINEIGDPLLIYSAFGNKRSRGAAR-----------------------------------------------------------------------'), Sequence(id='sequence336', source_id='XP_003673548.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNSSPADHEPIPDVRNQVDLQIGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVKLHSTDIVFSLMDLGGQKEFINMLPIAAVGSSVIVFLFDLTRPETLNSIKDWYRQVKGLNDIAIPILVGTKYDLLINLSAEYQEQISTAAIDYANVMDAPLIFCSTAESINVQKIFKIALAKIFNLTLVVPEIRDIGDPLLLYKELGNNIQKVKQSKSPQRLS----------------------------------------------------------------'), Sequence(id='sequence337', source_id='XP_003958955.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASEEHEKHQQIPFVRNQVDIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIVFSLMDLGGQREFINMLPLAAVGSAAIIFLFDLTRPETLESVKEWYRQAYGLNNQAIPILVGTKYDLFIDLDEEYQRQVSKTALDYSEVMDAPLVFCSTAKSINIQKIFKIALAKIFSLTLTISEIKDTGDPILLYKRFGSKLSKNKSSPSSSTKLK-TP-------RA---------------------------------------------------'), Sequence(id='sequence338', source_id='XP_001644471.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSSSIPKTRNQIEVQIGLVGDAQVGKTSLMVKYVQNIFNDEYTQTLGVNFLKRKVSVRSTDIVFSILDLGGQKEFINMLPIASIGSSAIIFLFDLTRPETLNSIKEWYRQANGLNDQAIPILVGTKYDLFIDLDQSTQEKISRIAMQYAQVMNAPLIFTSTAKSINVQKIFKIALSKIFNLTLTISEINEIGDPLLIYKTLGNRSTPIANASAS--SSA-------S-------------------SPS-------AST-----------------------'), Sequence(id='sequence339', source_id='XP_003684279.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPY------------RE-----NR-----N---------A-SSAGGMMRSVPKSRNQVEIQVGLIGDAQVGKTSLMVKYVQNIFNEEYTQTLGVNFLKRTVSVRSTDIVFSLLDLGGQKEFINMLPIATVGSAAIVFLFDLTRPETLNSIKNWYRQANGLNEMAIPILVGTKYDLFINLDKEHQDSISRLSMEIAQVMDSPLVFCSTSKSINVQKIFKIALSKIFNLTLTIPEINEIGDPLLIYKTLGNNFNNNRSHNSSPIRTNNNNNSNNDTNSNNDGNSNTVNNNNYSALDNSNYPNPTASEHLNRIKNLHQCLRHAQLRCLRVV'), Sequence(id='sequence340', source_id='SMN18735.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSEPKRNLVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISHTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNRNPTNVSASPVFSSQSS---SISPPKSKGTTAS--------------------------------------------'), Sequence(id='sequence341', source_id='CAD1779387.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPGSESKRNIVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYAQVMNAPIVFSSTAKSINIQKIFKIALSKIFNLTLTIPEITRTGDPLLIYRKFGNQNCKPTKVMTSPAFSSQTS---STSTSQVKAKETTAT------------------------------------------'), Sequence(id='sequence342', source_id='KAG0666170.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHSSSRRHQVPDVKNQVEIQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKINLRSTDIVFSLMDLGGQREFINMLPLASVGSSAIIFLFDLTRPETLDSVKEWYRQVYGLNNLAIPILVGTKYDLFIDMDKEYQKQISNTVLEYANVMNAPIIFSSTAKSINIQKIFKVALSKIFNLTLTIPEITRTGDPLLIYKKFGNQDRKSSKITTSSSQSSSSPASVSVSPRKSKSTITSS-------------------------------------------'), Sequence(id='sequence343', source_id='XP_022464898.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANVRSRHSSIPGIKNQIDVQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVNLRSTDIIFSIMDLGGQKEFINMLPLAAVGSSVIIFMFDLTRPKTLQSIKDWFRQAHGLNDSAVPILVGTKYDLSIETDERVPGNISCTAMRYAQVMNAPIVFCSTAKSIHIQKIFKIALAKIFNLTLTVPEIESIGDPLLIYRDFGNNVKRQSKSSPKRTGSMERT-PVSSQQ-----------------------------------------------------'), Sequence(id='sequence344', source_id='XP_003669861.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSSSPEHEPIPAVRNQVDLQVGLVGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNYLKRKVRLHSTDIIYSLMDLGGQREFINMLPIAAVGSSAIIFLFDLTRPETLNSIKDWYRQVNGLNDVAIPILVGTKYDLFIGLDSNYQNHISNSAIEYSKIMNSPLVFCSTAEGINIQKIFKIALAKIFNLTLVIPEITTVGDPLLIYKNLGNATNK---------------------------------------------------------------------------'), Sequence(id='sequence345', source_id='XP_003678517.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------------------------SE----------------------HRARTSKDSEANLAQPEEIQIQVGLVGDAQVGKTSLMVKYAQNGFDEEYTQTLGVNLLKRKVRIKSSNIVFSLMDLGGQKEFINMLPIASVNSSVIIFLFDLTRPESLESIKNWYMQAHGLNHDAVCILVGTKYDLFIDLPTEYQEQISRTSMKYAQAMDSPLIFSSSIASINIQKIFKIALAKVFDLTLIIPEITQIGDPLLIYKHLGSFAGRKRNNK----------------------------------------------------------------------'), Sequence(id='sequence346', source_id='KAG0659075.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQNTPTSINRHDPIPGVKNQIDIQIGLVGDAQVGKTSLMVKYVQNIFDNEYTQTLGVNFLKRKVKLRQTEIIFSLMDLGGQSEFINMLPLAAVGSSVIIFLFDLTRPVTLKSIKGWFRQAKGLNDLAIPILVGTKFDLFYTMDSQYQNEISKVAMEYSQVMDAPLIFCSTAKSIHIQKIFKIALAKLFNLTLTINEINLPGDPLLIYKDKGNNCINQSTNNNNNNTNLRRKSS--------HG--HTSNNNNNNNTPIQASPIAVRSSYNHR----HH-------------'), Sequence(id='sequence347', source_id='XP_451758.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLDKDRVPSLRHQVKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFVDMDPEYQENVSRTAMKYAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNLTLKVPEYKQIGEPLLIYKSFGPSRPSSP-KRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence348', source_id='NP_984991.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASENTIPQLKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFVNLDVAYQEELSKTSMRYAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNLTLRIPEIKDMGDPLLIYKSLGNAPQRVPS--------------------E------YTHHGRYRQ--------PEHIRNMAE----------Q--------'), Sequence(id='sequence349', source_id='XP_017989070.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVGESGIPQPKNEVKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGSTDVIFSIMDLGGQREFINMLPLVSNRAVAIIFLFDLTRPETLTSIREWFRQARGFNDTAIPLLVGTKYDLFINLDASYQEEISKTSMRYAQAMGAPLVFCSTASSINVQKIFKVIIAKAFRLTLRIPEIRDIGDPLLIYKSLGNSVPKRDAAGTVM-----AASSGYSPTSA------TVEQGQYRQ--------SERAQHTAS----------EQ-------'), Sequence(id='sequence350', source_id='KAG0673910.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTDKVPSLRHQVRVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGSTDVIFSIMDLGGQREFINMLPLVSEGAVAIVFLFDLTRPETLNSIKEWYRQARGFNETAISILVGTKYDLFVEMDSKYQEEVSRTAMKYAQVMKSPLIFSSTQSSINVQKIFKVVIAKAFNITLKVPEYKQIGEPLLIYKSLGPTRPPSPNKRQVH-----TPPPSS--------------------------------------------------------'), Sequence(id='sequence351', source_id='SMN21971.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSE----KNKVSPREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKRIRLRSTDITLSLMDLGGQREFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAIPILVGTKYDLFIEMDQDYQEEISRTCLKYAQIMDSPVIFSSSAYSINIQKLFKIIISKIFNLTLTLAEISDIGDPLLIYKEFGNTHLNGL-------------------------------------------------------------------------'), Sequence(id='sequence352', source_id='KAG0661436.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSTKLKSSKRPAKREEIQLQIGIIGDAQVGKTSLMVKYVQDIYNKEYTQTLGVNFLKKTIRLRSTDIVLSLMDLGGQKEFINMLPLAAMDSYCIILLFDLTRPETLKSVKEWYRQAFGLNKNAISVLVGTKYDIFIDMDEDYQEEISRTCIKYAQIMDSPVIFSSSAYSINIQKLFKIIVSKIFNLKLTIPEIRDIGDPLLIYEEFGNGHLNN--------------------------------------------------------------------------'), Sequence(id='sequence353', source_id='SCV02624.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MST----NEANVPTLPQPKNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIKLGSADIVFYIMDLGGQREFINMLPLASEGARAIIFLFDLTRPETLKSIKEWHRQATGFNEMAVPLLVGTKYDLFVNFDPEYQVQVSKQSMRYAQAMDAPLIFCSTSHSINIQKIFKVIIAKLYNLTMRASEIKQIGDPLLIYKHLGSKRRFSENPSSRNSSSR-TPSPHRSP------------------------------------------------------'), Sequence(id='sequence354', source_id='SCV99388.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSL----ATSDTPVLPHPTNTFTIKVGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLDKKIRLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNENAVPLLVGTKYDLFVNMDPEYQVQVSKQSMRYAQVMDAPLIFCSTSHSINVQRIFKIIIAKIYNLTMRASEIKQIGDPLLIYKYLGNSRRRSPSS-----------------------------------------------------------------------'), Sequence(id='sequence355', source_id='CUS20182.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----SMV----SGGDTPLLPHPKNTFTLKIGLIGDAQVGKTSLMVKYVENVFDEEYTQTLGVNCLSKKITLGSADILFYIMDLGGQREFINMLPLASEGAKAIIFLFDLTRPETLKSIKEWHRQATGFNEQAVPLLVGTKYDLFVNLDPDYQAQISKQSMRYAQAMDAPLIFCSTSHSINVQKIFKIVIAKLYNLTMRASEIKQIGDPLLIYKYLGSSRRPASGSSTSSGTS----------------------------------------------------------------'), Sequence(id='sequence356', source_id='XP_045933944.1', sequence='-------------------------------------MHFQQ----------------------------------------------------------------------QQQQHYHTPLRHGSDPAQ-HITNNSEEHINN--------YGNNTVDTPQQLRHTS---------AMTVINS---SQAATNNNYSDN---NNNT-SPVRG-----TTS----TAETIPDELIPRTTFRLKVGLIGDAQVGKTSLMVKYVQSVFDEEYIQTLGVHHLEKRESLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYLFDLTRPETLTSIKEWYRQAKGLNSKAIPLLIGTKYDLFIDMDPSYQEKMSRIGMLYAEAMNAPLIFSSTAESINVKIIFKIVVAKAFNLKLTVPEIKDLGDPILIYKNLGEKKKKN--------------------------------------------------------------------------'), Sequence(id='sequence357', source_id='KAA8901327.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTPS-----S------PSG-----------GG---------------------------SKATAAEAARNSVSLKVGMIGDAQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKVVSIRNTDITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDMFVNLAEEDQEEITKQAKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLKLTLPEITMTGEPLLIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence358', source_id='KAF8417303.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-SSTIA-------------SGSGAGGSYHHQQA------STS-------------SAGSALQETPGRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence359', source_id='KAF3929277.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RETSP----VSPLRASF--ANLN--------TEDHS---------QATAAIR---AQ---------------AGHTR-HESL--EKYTRR-DSTASE-NRNEEGY----------------------RERGSISSQSGAAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence360', source_id='OEJ86227.1', sequence='------------------------------------MTEYEN----------------------------------------------G----QQQQ---------RERIRGQERESYDEQERESYDEQERERIREQERRINN--------EQQRRVNNEQQ--------------------------RRXNNQQRST---TNDN-VSSNK-----NTH----KDLDLQDNLIPRTTFKLKVGLVGDAQVGKTSLMVKYVQSVFDDEYIQTLGVHHLEKTEFLKYADILFVINDLGGQREFINMLPIVSEDAVAIVYMFDLTRPETLTSIKEWYRQAKGLNNKAISLLVGTKYDLFIEMDSEYQEKISKIATLYSZAMNAPLIFSSTSESINVKVIFKIIVAKSFNLKLTIKEIXEIGDPLLLYKNLGNKHRISH-------------------------------------------------------------------------'), Sequence(id='sequence361', source_id='XP_046060918.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKNTVTLKVGLVGDAQVGKTSLMVKYVENCFDEVYTQTLGVNYMERSINIKSTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLSSIKDWYRQTRGFNRTAIPFLVGTKYDLFVDLSDAEQEEITRHAQKFARAMNAPLIFCSTSASINIQKIFKIVISKAFDLRLRIPEIENVGEPILIYHEHDRERERTSRRPTASHS-----------------------------------------------------------------'), Sequence(id='sequence362', source_id='EPS36031.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDASP----VSPLRASF--ANLN--------TDDHT---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRPEEGY----------------------RERGSISSQGGSAG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence363', source_id='KAI5807151.1', sequence='--------------------------------------------------------------------------MHELPLAPSLPPPQ----SPPTPDR----------YSQGAARHY---HSNSAAS-A-----PAMIG-----------DA-------AGAYYRGSPPPPMPQQPYVP-R----D-RS-SESYHNGSS--------------------AQQ-QQQQYAMEQKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFTREEQEEVSKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence364', source_id='XP_011117899.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RESSP----VSPLRASF--ANLN--------ADDHS---------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-NRNDESY----------------------RDRSSVSSQG-GSG-AKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGLNKTAIPFLIGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVEAGNR----------------------------------------------------------------------------'), Sequence(id='sequence365', source_id='KAI1438264.1', sequence='---------------------------------------MEQDLHTTPGADLE----------P--HGLPDD---GSI---------SSIEDTPEA--------AS--SLNGHETYHQ---HPQSLDYVV-----SSS---------------QNTDETDPNAQYET-VPATSQAQSISR-PPSGLSGAGGDRQAA------------------------HSDRGSNGADHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSRDEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence366', source_id='XP_022456167.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNSVSLKVGLVGDAQIGKTSLMVKYVEGCFNEDYTQTLGVNFMERSILIKNTQITFSIWDLGGEREFLNMLPLVSSDAVAILFMFDLTRKSTLNSIKEWYRQTRGFNKTAIPFLVGTKYDLFIDMPMEDQEEVTTQARKFAKAMNASLIFCSTSASINIQKIFKIVISKAFDLRLTIPEVTHIGEPILLYQGV---------------------------------------------------------------------------------'), Sequence(id='sequence367', source_id='KAF3908940.1', sequence='---------------------------------------MTTTPP-------------------------------TK------------RDVSP----VSPLRASF--ANLN--------TTDDGQS--------ATAAIR---AS---------------AGHTR-HESL--EKYTRR-DSTASE-SRNEDGY----------------------RERSSISSQG-GSGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENTGDPLLIYQDVELGNR----------------------------------------------------------------------------'), Sequence(id='sequence368', source_id='XP_006693239.1', sequence='---------------------------------------MERDQLAAPAPSE------------------S-----AA---------SDYRDHSLADAEVAPSSDCE--NNGFHDHHY--SQSQHYDQ-------DDAAESE---PT---------------ARYNT-PSGS--GQQISR-PPSGLS-GERGAGYATDQGSRAG------------SNSASQEQQQQQSQQPPARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYKDV---------------------------------------------------------------------------------'), Sequence(id='sequence369', source_id='EWC45326.1', sequence='---------------------------------------MATTPP-------------------------------TK------------RDTSP----VSPLRASF--ANLN--------TTDDGQQ-------SAAAAIR---AA---------------AGHTR-HESL--EKYTRR-DSTASE-SRNDDGY----------------------RERSSISSQGGGAGGNKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNLSKEDQEEISKQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGDPLLIYQDVETGNR----------------------------------------------------------------------------'), Sequence(id='sequence370', source_id='KAF3930522.1', sequence='---------------------------------------MTTTPP-------------------------------TK---------QGSRNVSP----VSPLRASF--ANLN--------TTDENHS-------SATAAIR---AA---------------AGHTR-HESL--EKYTRR-DSNASE-SKNEDGY----------------------RERSSVSSQGGS--SQKKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNLSKEDQEEISRQAKRFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGDPLLIYQDVESGNR----------------------------------------------------------------------------'), Sequence(id='sequence371', source_id='KAF8249497.1', sequence='-----------------------------------------------------MQ------Q-HDDDALPQP-QTTELPLAPSLPPPVALAHSPPTPRR----------RNSSPTRHY---HSSSNASGA-----PPYIG-----------SP---GSVESAQYYNSQGSPPTPAAPHQQ-QQFATS-RA-DGGYHNGGG-------------------------YAQQQLEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence372', source_id='XP_002174495.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEQTKNSVTIKLGMVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDYFVGLSREDQEEITKQARRYAKVMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEITAVGEPILEYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence373', source_id='PRP83484.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------MG-----------DQ---NDTE-------------ARIGHSR-LPFFIM-SG-DGEYTG-----------------------------SGKAGEGKKNSVVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIKGTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDFFANLPAEEQEEITKQARKFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLSCTIPEIIKVGEPILEYQNLS--------------------------------------------------------------------------------'), Sequence(id='sequence374', source_id='GAA97202.1', sequence='-------------------------------------------------------------------------------------------------------------------------MASSTSTG---------AG-----------SS---SSRQRQESYRSS--------------------------HSQQSS--------------------SQH-APAPAPQDDDRNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKSISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSTLAESEQEDVTRQAKRFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTLPEITETGEPLLLYQDI---------------------------------------------------------------------------------'), Sequence(id='sequence375', source_id='OBA26219.1', sequence='------------------------------------MESML-------------------------------------------------------------------------------------QSHNRRR-HTNSMSISG--------SSNNNVHSELRQNNNN---------RISSMPS---SQPASN----------SNN-KPVDN-----IKLTEKDMNKYIDKDLVPKTTFKLKVGIIGDAQVGKTTLMCKYVNSAFDDEYIQTLGIHHLQKKETLKYSNILFTINDLGGQREFINMLPIVSEGAVAIIYLFDLTQPESLNSIKEWYRQAKGLNEKAISILVGTKYDLFLDLDPEYQTNISQIATLYSEAMNAPLIFASTAASINVKIIFKVIVAKAFGLDLAVPEITQIGDPLLIYKKLGNVIKQIKR------------------------------------------------------------------------'), Sequence(id='sequence376', source_id='KAI1823332.1', sequence='---------------------------------------MEQDFHAVPAPDSE----------P--HDHPDD---G-L---------GGLEESPDI--------AP--GSNGHELYHQ---HPQSLDYVI-----SNN---------------QNIDDVDPNAPYEA-VATTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGAEHPSARNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence377', source_id='CDO57487.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIPS-----IYPNH-KPTGM--------YTGQ-----------------------FISTLHPCANYPFFSRVSLKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRNTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDLFANLPEEDQEEISTQSKRFAKAMKASLIFCSTSHSINVQKIFKIVLSKAFDLRLTLPEITNTGEPLMIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence378', source_id='KAI2629167.1', sequence='---------------------------------------MDQD--------PM----------A--TPIPHDVHDDTL---------GGIEGSMHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNA---------------HPDEVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence379', source_id='KAI5811198.1', sequence='---------------------------------------MSNDPL----PTIP----------SA-TSSTVD----LS---------NG--NDGSA---QNE---N---EPPHRSQHH--TGM------------TSIHL-----NDPTSQSNAA---ASYSQTHSG-ATMLS-------------SGSGATGSFQQAGG------PSSGGP-----AGAQTQGQQALGGDYSRRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPKEDQEEISKQARKFARAMKASLIFSSTSHSINIQKIFKIVLSKSFDLKCTIPEIEQVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence380', source_id='KAG9017701.1', sequence='------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTAASGSGAPPAT--------------------PLS-AASADLGGDERNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRRTTITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFATFSRDEQEEITKQAKRFAKAMHAPLIFCSTSSSINVQKIFKIVLAKAFDLKCVIPEVHNVGEPLLIYMDQ---------------------------------------------------------------------------------'), Sequence(id='sequence381', source_id='OTA67948.1', sequence='-----------------------------------------------------------------------------------------MHFPGHLP---------DEPSSSSHEPHH--RQSQSLDQGL-----ANSAHP-----------HPHPDDIDPNAQYEA-QQYDPPQQSTQR-PPSSMSS-TGERQY---------------------TEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence382', source_id='KAH6626466.1', sequence='MEQEQQAMAPPLPITPTTGIASDAPLVP---A-----------AAAAQVPLPH----------SLSPPLQIDPHDDTL---------SSAGTVSHQ---ALPDHNNFHEHNGYHD------QPQHPIQFQ-----PLDHSVN---NSPRSYYPADQTDSEPTARYAT-PPVA--APAISR-PSSGLSGQGAGYGAD--HVSRAG-----------------SNGAAAESSQAPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence383', source_id='ORX96310.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAEAQKKNSVVVKVGLVGDAQIGKTSLMVKYVEGAFDEDYIQTLGVNFMEKTIHIRNTEITFSLWDLGGQREFINMLPLVCNDAVAILFLFDLSRKSTLNSIKEWYRQARGFNKTAIPILVGTKYDQFAECPPEEQEEVTRQARKFSKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLRCTIPEISDVGAPILEYHID---------------------------------------------------------------------------------'), Sequence(id='sequence384', source_id='XP_028477951.1', sequence='---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTD-P--------------------------------GYASSG-SGSGRVSGGEGGDRNAIVLKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAITIRNTEITFSIWDLGGQREFVSMLPLVSNDAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDKFAALSREEQEEITKQAKRFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDLKCVIPEIDQVGEPILLYNDL---------------------------------------------------------------------------------'), Sequence(id='sequence385', source_id='XP_024666830.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRDRVPVDLNDQQQQVTVKVGLIGDAQIGKTSLMVKYVNNTFDDDYIQTLGVNFLEKSVNIRNTQITFSIWDLGGQREFINMLPLVCNDAAALVFMFDLTRKSTLNSVRNWYRQARGFNRTAVPLLVGTKFDMFYEMSDQEQLEITEQAKKYAQAMKAPLVFCSTAMGINVQKLFKIVLAKTFDLKLTIPELAATGEPILIYQQW---------------------------------------------------------------------------------'), Sequence(id='sequence386', source_id='KAI0099584.1', sequence='-----------------------------------------------------------------------------------------MHIPGHLP---------GES-SSSHEPHH--RQSQSLDQGL-----ANSAP-------------PLPDDIDPNAQYEA-HQYDPPQQPVQR-PASSMSS-TGERQY---------------------NEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence387', source_id='KAI1801530.1', sequence='---------------------------------------------------------------------------------------------MHIA---------GEPGV--HEPHH--RQSRSLDQGL-----ANSAHADDIDTHAVDPHAIDPIAVDHNAQYEA-HSYEPPAQSMSR-PASS--SGTGERHL---------------------NGE--ASREGNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence388', source_id='KAF9351078.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD-------------------------TPESTKKGSGNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKTTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence389', source_id='KAF9160900.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATS-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATYCDRDRKKLTI-----------------------------------------------------------------------'), Sequence(id='sequence390', source_id='KAG0263740.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAGD-------------------------SGKKS--SSPNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYTDK---------------------------------------------------------------------------------'), Sequence(id='sequence391', source_id='KAI1135662.1', sequence='-----------------------------------------------MEQDPV----------A--APVPHDIHEDTI---------GGIEGSMHIP---------AEPSTSHEPHRH--RQSQSLDRGL-----ASSK---------------HPEDIDPNAQYDT-PQYDPPQQSMPR-PASS-SS-AGERHY---------------------AEQ--ASRESNGA-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence392', source_id='XP_045969802.1', sequence='---------------------------------------MTTTPP----PLEN----------NGSLPSHID----ID---------VA---------------------ATPRQEHY--TSSSD----------PSLAFSP---QDSNSPSRAN---IGDDQRHSG-TPPLSQSQLY--------GNGGGMNSFTSAAG------AA----------------AGGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence393', source_id='KAI1414505.1', sequence='-----------------------------------------------------------------------------------------MHFSGE--------------PSSSHEPLH--RQSQSLDQGL-----ANSAHP-------------HPDDIDPNAQYEA-HQYDPPQQSMQR-PTSSMSS-GGERHY---------------------TEQ--APRESNGT-DRNARNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence394', source_id='KAG0239750.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATLGD-------------------------SGKKSSNSSHNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAIPFLVGTKYDYFTMFSKEEQEEVTKQARKFARAMKAPLIFCSTAQSINVQKIFKIVLSKAFDLKCTIPEINEAGAPILEYQSY---------------------------------------------------------------------------------'), Sequence(id='sequence395', source_id='XP_044688071.1', sequence='---------------------------------------MTTTPP----PPEN----------NGSLPSHID----VD---------VA---------------------ATPRQEHY--TS-SD----------PSLTFSP---QDSNSPSRAI-----GDERNSG-TPPLSQSQLY--------GNGGGMNNFTSAAA------------------------AAGGQGAEAKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDVM--------------------------------------------------------------------------------'), Sequence(id='sequence396', source_id='RPB01516.1', sequence='---------------------------------------MTTTPPLLFSPSP-------PPP-LPDSLYPDEPEEVTTPTA-TLPPPP------PSPPP----------RQPSPARHQ---HSGSAPA---------TVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGG-----------------------------GGAVDMGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence397', source_id='KAG0236582.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAA-----------------------------SADS--ARRSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDFFSTFSKEEQEEITKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEPGAPILEYTS----------------------------------------------------------------------------------'), Sequence(id='sequence398', source_id='KAH6640987.1', sequence='MEQD-QAIS------PAYAVAPDSALA------------------PARIP--------------SPAGFPTDPHDDTL---------SGVESVTHQ---AVPDHH-IHEHNGFHE------Q-QHISQLQ-----PLDHNVT---NSPRSPYPTDTTDSEPTARYAT-PPIQ--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence399', source_id='XP_002493958.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDSPR-------------------RNQHRRS----------------------HSEQQNVPHSQRETNSVAVKIGLIGDAQIGKTSLMVKYVEGCYDENYTQTLGANFMERIINIRNTQITLSIWDLGGEKEFINMLPLVTTDAVVIIFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDLFIDLPDEDQIEITNQAKKYARAMSASLIFSSTSHSINIQKLFKVILSKVFDIKATIPEIVNTGEPLLLYQSI---------------------------------------------------------------------------------'), Sequence(id='sequence400', source_id='KAA8914877.1', sequence='---------------------------------------MTTTPPPSRTSTSDMDHSARTPS-SSSSSIPEEYIHTELRLAPS----LSSLQSPPTPDR----------GSPSRYHHS---HSNSATSAP----------------------------SDGASYYGGSPPA-MRDRD-RE-GYYGNGAGA-AGGSGGGAG--------------------SSA-YNMAEQQRTKQNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQEV---------------------------------------------------------------------------------'), Sequence(id='sequence401', source_id='XP_018701974.1', sequence='---------------------------------------METDDV--PAATLH----------D-----NLD----DT---------LG----GLDGSPQVPSSSHY--SNHHHDHQY--QNPHHSNN-------DTHEHEP---QSPG-GGPSH---HQ-QQHHDE-DPPC--TRY-TP-PAPGSS-APASAAPGSRAGSEMSNPSSSQQQHQAYGEYASSRQGSGEPAAPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPIQDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence402', source_id='KAI2643608.1', sequence='---------------------------------------MEHDLHGAPVSGLE----------P--HAHHDD---DSL---------NDADEHSDI--------AS--SLNGHESYHQ---PSQSLDYVL-----SHG---------------QDTDEADPNSQYET-QPTTSQPQSISR-PPSGLSGAGGDRQTA------------------------HSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence403', source_id='KAG0125076.1', sequence='---------------------------------------MTTTPPPLFSPSP-------PPP-LPDSLCPDDPEEVTTPTS-NLPPPP-----LPSPPP----------RQPSPVRHH---HSGPAPA---------AVG-----------NF---GSPP------PNPPPPPQSLAYQQ-N--GAGTTPTQAHYGS-----------------------------GGAVDLGKRNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFVNFPREDQEEISKQARKFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIEHVGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence404', source_id='KAH9904989.1', sequence='---------------------------------------MEQDPV--------------------AAAVPQDGYDDTLG---------GIEGSPHVGPT----------QINREKRHQ---QSQSLDNGL-----P-NNG-----------HA---DEIDPNARYDTPPN-PLQPHSISR-PPSGLS-GAGDRHNAYSDH--------------------ASR-GSNGAEQNNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence405', source_id='VEU24358.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------MDNRSVSTRIPRSHSTSEALSEEPARSVSSTV--DGYDNYY-----------GHQH---HHAHRHRYGEEERQSAEKNTVTIKVGLIGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIKNTEITFSIWDLGGEAEFTNMLPLVASDAVAVLFMFDLSRKSTLNSVKDWYRQARGFNRTAIPFLVGTKYDLFVDLPDEEQEEITRQARKYAKAMNAPLIFSSTCASINIQKIFKIVISKTFDLRLKIPEIVNTGEPILLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence406', source_id='KAI1283572.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--EPLPDTF---------ADVEGGPHV--------SP--SQNGHEVYHHHHQQSQSLDHGL-----ASS---------------QNHDEADLNGRYET-PPSTAHPQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence407', source_id='KAI1500557.1', sequence='--------------------------------------MMEHDPAFATAPGPH----------N-----GIDD--------------------MLGGIEGSPTLASG--QNGHETYHH--HHSQSFDQ-------E----IP---LN---ENPDD---MDTTAQYDT-PPVTAQPQSISR-PPSALD-GAAGER-----------------------HASNGDRGSNGADYNNTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENIGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence408', source_id='KAI2623093.1', sequence='---------------------------------------MDQDPITTPVQAPA----------Q--DPTPHELHEDTF---------GGIEGSMHLS---------GEPGT--PEAHH--RQSQSLDQGL-----ANSV---------------HPDEVDPNTQYEA-HQYDAPPQSMPR-PASSMSG-AGERQY---------------------PEH--ASRESNGA-DRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence409', source_id='NP_593285.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR---------------------------------------------------------------------------------'), Sequence(id='sequence410', source_id='KAI0431960.1', sequence='------------------------------------MDTMEQDFHAAPIPGPH----------E--HLD--ETLPDTL---------ADVEGAPHV--------SP--SQNGHEVYHHH-QQSHSLDQGL-----ANS---------------QTSDEPDLNGRYET-PPSTGHAQSISR-PPSGLS--GGDRQTA------------------------YSDRGSNGADQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence411', source_id='KAH8926511.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSAGP-----LALE-----KGGAEAGEKNSVVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFSNFSRDEQEEITRQSRRFARAMKAPLIFCSTSHSINVQKIFKIVLSKSFDLKCTIPEITDVGEPMLIYIDV---------------------------------------------------------------------------------'), Sequence(id='sequence412', source_id='RMJ24013.1', sequence='-----------------------------------------MNPS-------------------------------YH---------NGYSSDSHA--QYSTGPAGF--NPPVHDS-----TSQDAEQ-------TRLTFSP---SI---------------TQQPQ-PPSL---SRPS---SAFSS-GPERHG-------------------------ASQQHHETSQRAQPAKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLIGTKYDHFVNFPREDQEEISVQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENVGEPLLLYKSV---------------------------------------------------------------------------------'), Sequence(id='sequence413', source_id='KAF8931046.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAATG-----------------------------ES--AKKSSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEISEAGAPILEYASN---------------------------------------------------------------------------------'), Sequence(id='sequence414', source_id='ODQ76250.1', sequence='-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSS------AA----------------PNGSDGSVARKNAVVIKVGMIGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRDTEITFSIWDLGGQREFVNMLPLVSNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDTFAQFPREDQEEITKQARRFAKVMKASLIFCSTSHSINIQKIFKIVLSKAFELKCVIPEIATIGDPILLYHDV---------------------------------------------------------------------------------'), Sequence(id='sequence415', source_id='KXJ93426.1', sequence='---------------------------------------MDQEPAAL------------PPTRNPLDVAPDD----TL---------GGIESSPRVYSD----------PESTIRTHH---HSQSLDQGL-----ASSAH-----------YQHNSEDMD-HQTRQDTPPIPQQPQSISR-PPSGLSGAGDRQPAQYSDH--------------------ASRSSGGQPEPQNGRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFPREDQEEISNQARRFAKAMRAPLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence416', source_id='XP_051368163.1', sequence='---------------------------------------MDQDLLG-----------------T--PTAPHDTLDDAL---------AGVEGPLHLA---------SESGN--LEPHH--RQSQSLDRGL-----ANNAQVDDF---------------DTAVPFDS-PQYDTPPPAMQR-PASSD-SAAGEKQL---------------------AEH--ASREANGADRNNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence417', source_id='GES63634.1', sequence='-------METIHNL--NTGV-SEPVEQQP------QESAFEASPVSHPAGSTD----------E-----PTSASVYHR---------SGYNSDSHA--QYSSLA----------------------------------------------------------THQPQ-PP------TSSR-PSSGLS-GPERYGP----------------------SQEVTQKQPSQPPSSQTKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNV---------------------------------------------------------------------------------'), Sequence(id='sequence418', source_id='RPA74746.1', sequence='--------------------------------------------------------------------------------------------------------------------------------------------------M---------------ADHHE-GSSH---SYDR---TSHSS-RP-------------------------------ATAEKQPAPKEETKNSVVIKVGMVGDAQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHYVNFPIEDQEEISKQAKRFAKAMKASLIFSSTSHSINIQKIFKIVLSKAFDLKCTIPEITEIGEPLLLYQDV---------------------------------------------------------------------------------'), Sequence(id='sequence419', source_id='XP_024675402.1', sequence='-------MDTPQPSDPLAGVAPERHEQHPQPQSAPQQSQYPVNPA-GPYPSHV----------ESVPPEVIPSASTYH---------AGYSSDSHAN--YSSNAVDF--NS--------------------------GSEYP---PQPRAELPRA---QEAVPSMMH-PPAA---PSSSR-PSSGLSSGPDRL-----------------------GSVQSGQELPQKQPIPSNKNSVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFVNFPREDQEEISIQAKRFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDLKCTIPEIENIGEPLLLYKNL---------------------------------------------------------------------------------'), Sequence(id='sequence420', source_id='KAH6850716.1', sequence='MEQE-QAFN------PAYTMAPDPALA------------------PAPIPAPI----------SSPVGLPTDPHDDTL---------SGVESVTHQ---ALPDHN-IHDHNGFHE------Q-QHLVQLQ-----PLDHSVN---NSPRSPYPTDTTDSEPTARYAT-PPIP--APTISR-PPSGLSGQGAAYGAD--QVSRAG-----------------SNGAQAESSQSPGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNLSREEQEEISNQARRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEITNVGEPLLIYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence421', source_id='PHH71636.1', sequence='---------------------------------------MEHQQPE-LDQ--Q----------PPPLHAAHDSLDDTL---------GGIEGSPHVAA----------ANNGFHQ------QSQSLDSAV-----P---------NSPR--------YDDDAANRHT-P-PVSSAPSLSR-PGSQMS-----------------NPSSSNPPQQMHG----NDHRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence422', source_id='KAJ3562589.1', sequence='------------------------------------MDTMEQDLHTTPIPGVH----------E--HHHLDDALPDPH---------ADVDARPHS--------AP--GQNGHEVYH---QQSHSLDQGI-----AHG---------------QHPDEADLNGRYDT-PPSATHPQSISR-PPSGLSGAGGDRQTT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQQTV--------------------------------------------------------------------------------'), Sequence(id='sequence423', source_id='RDA84390.1', sequence='---------------------------------------MDHQPAA-DQEQPQ----------ELPRPASHDGLDDTL---------GGIEGSPHPVA----------SSNGFHA------HQ-----EA-----P---------GSPR--------YDDDNAARQT-P-PVSA--PLSR-PGSQMS-----------------N-----PPQHASG----SDYRQGSNEPPNGRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPPQDQEEISNQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQNV---------------------------------------------------------------------------------'), Sequence(id='sequence424', source_id='XP_007413704.1', sequence='----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNMTSSTGP-----AGSSGSTSNSSLQQNDDKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAAFSKDEQEEITRQSRRFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDLKCTIPEINGSGEPLLIYLDV---------------------------------------------------------------------------------'), Sequence(id='sequence425', source_id='KAI0376630.1', sequence='---------------------------------------------------------------------------------------------MHLP---------NEPHN--HETHH--RQSQSLDQGL-----ANNV---------------HPDDVDPNAQYEA-HQYDQPSQSVPR-PASSMSSTGGERQY---------------------SDQ--AARESNGAADRNTRNHVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFVNFPREDQEEISNQAKRFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSV---------------------------------------------------------------------------------'), Sequence(id='sequence426', source_id='XP_047831721.1', sequence='---------------------------------------MEQDFHTAPIPGPR----------E--HLDALPDTHDTH---------ADVVARPHT--------AP--DQNGHEVYH---QQSQSLDQGL-----SDS---------------QHHDDADVAGRYET-HPSTTHPQSISR-PPSGLSGAGGDRQAT------------------------YSDRGSNGTDQASTRNQVVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPLVCNDAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFVNFSREEQEEISSQARRFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDLKCTIPEIENVGEPLLLYQSC---------------------------------------------------------------------------------'), Sequence(id='sequence427', source_id='KAI9294962.1', sequence='-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEEGKNSVVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRNTEITFSIWDLGGQHEFVNMLPLVCNDAVAILFMFDLSRKATLNSIKEWYRQARGFNKTAMPFLVGTKYDHFASFNREEQEEITKQARKFAKAMRAPLIFCSTSHSINVQKVFKVVLSKAFDLKCTIPEISDIGAPILEYEVGSE-------------------------------------------------------------------------------')], standard_numberings=[StandardNumbering(id='standardnumbering201', reference_id='BAH60832.1', numbered_id='CAI4663910.1', numbering=['0.1', '0.2', '0.3', '0.4', '0.5', '0.6', '0.7', '0.8', '0.9', '0.10', '0.11', '0.12', '0.13', '0.14', '0.15', '0.16', '0.17', '0.18', '0.19', '0.20', '0.21', '0.22', '0.23', '0.24', '0.25', '0.26', '0.27', '0.28', '0.29', '0.30', '0.31', '0.32', '0.33', '0.34', '0.35', '0.36', '0.37', '0.38', '0.39', '0.40', '0.41', '0.42', '0.43', '0.44', '0.45', '0.46', '0.47', '0.48', '0.49', '0.50', '0.51', '0.52', '0.53', '0.54', '0.55', '0.56', '0.57', '0.58', '0.59', '0.60', '0.61', '0.62', '0.63', '0.64', '0.65', '0.66', '0.67', '0.68', '0.69', '0.70', '0.71', '0.72', '0.73', '0.74', '0.75', '0.76', '0.77', '0.78', '0.79', '0.80', '0.81', '0.82', '0.83', '0.84', '0.85', '0.86', '0.87', '0.88', '0.89', '0.90', '0.91', '0.92', '0.93', '0.94', '0.95', '0.96', '0.97', '0.98', '0.99', '0.100', '0.101', '0.102', '0.103', '0.104', '0.105', '0.106', '0.107', '0.108', '0.109', '0.110', '0.111', '0.112', '0.113', '0.114', '0.115', '0.116', '0.117', '0.118', '0.119', '0.120', '0.121', '0.122', '0.123', '0.124', '0.125', '0.126', '0.127', '0.128', '0.129', '0.130', '0.131', '0.132', '0.133', '0.134', '0.135', '0.136', '0.137', '0.138', '0.139', '0.140', '0.141', '0.142', '0.143', '0.144', '0.145', '0.146', '0.147', '0.148', '0.149', '0.150', '0.151', '0.152', '0.153', '0.154', '0.155', '0.156', '0.157', '0.158', '0.159', '0.160', '0.161', '0.162', '0.163', '0.164', '0.165', '0.166', '0.167', '0.168', '0.169', '0.170', '0.171', '0.172', '0.173', '0.174', '0.175', '0.176', '0.177', '0.178', '0.179', '0.180', '1', '2', '3', '3.181', '3.182', '3.183', '3.184', '3.185', '3.186', '3.187', '3.188', '3.189', '3.190', '3.191', '3.192', '4', '5', '5.193', '5.194', '5.195', '5.196', '5.197', '6', '7', '7.198', '7.199', '7.200', '7.201', '7.202', '8.203', '8.204', '8.205', '8.206', '8.207', '8.208', '8.209', '8.210', '8.211', '8.212', '9.213', '10', '11.214', '12.215', '13.216', '14.217', '15.218', '16.219', '17.220', '18.221', '19.222', '20.223', '21.224', '22.225', '23.226', '24.227', '25.228', '26.229', '27.230', '28.231', '29.232', '30.233', '31.234', '32.235', '33.236', '34.237', '35.238', '36.239', '37.240', '38.241', '39.242', '40.243', '41.244', '42.245', '43.246', '44.247', '45.248', '46.249', '47.250', '48.251', '49.252', '50.253', '51.254', '52.255', '53.256', '54.257', '55.258', '56.259', '57.260', '58.261', '59.262', '60.263', '61.264', '62.265', '63.266', '64.267', '65.268', '66.269', '67.270', '68.271', '69.272', '70.273', '71.274', '72.275', '73.276', '74.277', '75.278', '76.279', '77.280', '78.281', '79.282', '80.283', '81.284', '82.285', '83.286', '84.287', '85.288', '86.289', '87.290', '88.291', '89.292', '90.293', '91.294', '92.295', '93.296', '94.297', '95.298', '96.299', '97.300', '98.301', '99.302', '100.303', '101.304', '102.305', '103.306', '104.307', '105.308', '106.309', '107.310', '108.311', '109.312', '110.313', '111.314', '112.315', '113.316', '114.317', '115.318', '116.319', '117.320', '118.321', '119.322', '120.323', '121.324', '122.325', '123.326', '124.327', '125.328', '126.329', '127.330', '128.331', '129.332', '130.333', '131.334', '132.335', '133.336', '134.337', '135.338', '136.339', '137.340', '138.341', '139.342', '140.343', '141.344', '142.345', '143.346', '144.347', '145.348', '146.349', '147.350', '148.351', '149.352', '150.353', '151.354', '152.355', '153.356', 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'254.432', '254.433', '254.434', '254.435', '254.436', '254.437', '254.438', '254.439', '254.440', '254.441', '254.442', '254.443', '254.444', '254.445', '254.446', '254.447', '254.448', '254.449', '254.450', '254.451', '254.452', '254.453', '254.454'])])"
- ]
- },
- "execution_count": 14,
- "metadata": {},
- "output_type": "execute_result"
- }
- ],
- "source": [
- "alignment"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 7,
- "metadata": {},
- "outputs": [
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 2/2 [00:00<00:00, 660.05it/s]\n"
- ]
- }
- ],
- "source": [
- "from pyeed.core import ProteinInfo, Alignment\n",
- "from pyeed.aligners import PairwiseAligner\n",
- "\n",
- "# Get sequences\n",
- "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\"]\n",
- "sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
- "\n",
- "# Create and run alignment\n",
- "alignment = Alignment.from_sequences(\n",
- " sequences, aligner=PairwiseAligner, mode=\"local\")"
- ]
- },
- {
- "cell_type": "markdown",
- "metadata": {},
- "source": [
- "## Multi Pairwise Alignment"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 18,
- "metadata": {},
- "outputs": [
- {
- "name": "stderr",
- "output_type": "stream",
- "text": [
- "⬇️ Fetching protein sequences: 100%|██████████| 4/4 [00:00<00:00, 40.43it/s]\n",
- "⛓️ Running pairwise alignments: 100%|██████████| 4950/4950 [00:00<00:00, 17443.83it/s]\n"
- ]
- }
- ],
- "source": [
- "%reload_ext autoreload\n",
- "%autoreload 2\n",
- "from pyeed.core import ProteinInfo, Alignment\n",
- "from pyeed.aligners import PairwiseAligner\n",
- "from pyeed.network.network import SequenceNetwork\n",
- "\n",
- "\n",
- "ncbi_accessions = [\"QGC48744.1\", \"AAT46413.1\", \"AAT46414.1\", \"AAT46415.1\"]\n",
- "sequences = ProteinInfo.from_ncbi(ncbi_accessions)\n",
- "\n",
- "# Create and run alignment\n",
- "alignments = Alignment.from_sequences(blast_results, aligner=PairwiseAligner)"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 9,
- "metadata": {},
- "outputs": [],
- "source": [
- "n = SequenceNetwork(\n",
- " sequences=sequences,\n",
- " pairwise_alignments=alignments,\n",
- " threshold=0.5,\n",
- " weight=\"identity\",\n",
- " color=\"organism\",\n",
- " label=\"organism\",\n",
- ")"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 10,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "pairwisealignment1\n",
- "pairwisealignment2\n",
- "pairwisealignment3\n",
- "pairwisealignment4\n",
- "pairwisealignment5\n",
- "pairwisealignment6\n"
- ]
- },
- {
- "data": {
- "text/plain": [
- "EdgeView([('QGC48744.1', 'AAT46413.1'), ('QGC48744.1', 'AAT46414.1'), ('AAT46413.1', 'AAT46414.1')])"
- ]
- },
- "execution_count": 10,
- "metadata": {},
- "output_type": "execute_result"
- }
- ],
- "source": [
- "n.graph().edges()"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 11,
- "metadata": {},
- "outputs": [
- {
- "name": "stdout",
- "output_type": "stream",
- "text": [
- "QGC48744.1 AAT46413.1\n",
- "QGC48744.1 AAT46414.1\n",
- "QGC48744.1 AAT46415.1\n",
- "AAT46413.1 AAT46414.1\n",
- "AAT46413.1 AAT46415.1\n",
- "AAT46414.1 AAT46415.1\n"
- ]
- }
- ],
- "source": [
- "for alignment in alignments:\n",
- " print(\n",
- " alignment.aligned_sequences[0].source_id,\n",
- " alignment.aligned_sequences[1].source_id,\n",
- " )"
- ]
- },
- {
- "cell_type": "code",
- "execution_count": 12,
- "metadata": {},
- "outputs": [
- {
- "ename": "NameError",
- "evalue": "name 'construct_network' is not defined",
- "output_type": "error",
- "traceback": [
- "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m",
- "\u001b[0;31mNameError\u001b[0m Traceback (most recent call last)",
- "Cell \u001b[0;32mIn[12], line 1\u001b[0m\n\u001b[0;32m----> 1\u001b[0m \u001b[43mconstruct_network\u001b[49m(alignments, \u001b[38;5;241m0\u001b[39m)\n",
- "\u001b[0;31mNameError\u001b[0m: name 'construct_network' is not defined"
- ]
- }
- ],
- "source": [
- "construct_network(alignments, 0)"
- ]
- }
- ],
- "metadata": {
- "kernelspec": {
- "display_name": "pye",
- "language": "python",
- "name": "python3"
- },
- "language_info": {
- "codemirror_mode": {
- "name": "ipython",
- "version": 3
- },
- "file_extension": ".py",
- "mimetype": "text/x-python",
- "name": "python",
- "nbconvert_exporter": "python",
- "pygments_lexer": "ipython3",
- "version": "3.10.13"
- }
- },
- "nbformat": 4,
- "nbformat_minor": 2
-}
From 1b65a2878f51fc72463c5f555f34c9119388a8fa Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Fri, 23 Feb 2024 11:15:38 +0100
Subject: [PATCH 10/13] removed old example
---
examples/networks/tem109_accession.toml | 102 ------------------------
examples/networks/tem1_accessions.toml | 102 ------------------------
2 files changed, 204 deletions(-)
delete mode 100644 examples/networks/tem109_accession.toml
delete mode 100644 examples/networks/tem1_accessions.toml
diff --git a/examples/networks/tem109_accession.toml b/examples/networks/tem109_accession.toml
deleted file mode 100644
index 2f1eee6e..00000000
--- a/examples/networks/tem109_accession.toml
+++ /dev/null
@@ -1,102 +0,0 @@
-tem109_ids = [
- "WP_063864949.1",
- "WP_063864799.1",
- "WP_063864870.1",
- "WP_032490103.1",
- "WP_063864912.1",
- "WP_063864909.1",
- "WP_063864800.1",
- "WP_047028173.1",
- "WP_063864877.1",
- "ANG18301.1",
- "WP_063864805.1",
- "ARF39029.1",
- "WP_032490956.1",
- "ARF31230.1",
- "HBQ2613975.1",
- "WP_063864852.1",
- "WP_063864859.1",
- "WP_063864865.1",
- "AMM70781.1",
- "HCF8861892.1",
- "WP_013279314.1",
- "EKW4005960.1",
- "EJG7116187.1",
- "ARF31817.1",
- "HAI5030310.1",
- "HBX5023813.1",
- "WP_042065300.1",
- "WP_000027057.1",
- "WP_063864833.1",
- "WP_063864797.1",
- "HCO3480053.1",
- "WP_032072208.1",
- "ARF38043.1",
- "ARF26548.1",
- "HBX5023809.1",
- "ARF39336.1",
- "WP_063864851.1",
- "WP_188240090.1",
- "WP_063865030.1",
- "ANG32478.1",
- "ANG13631.1",
- "ANG17132.1",
- "ARF28164.1",
- "WP_015379489.1",
- "ARF29524.1",
- "HBW1251876.1",
- "ARF30334.1",
- "ANG31477.1",
- "ANG23480.1",
- "ANG31365.1",
- "HDN1137928.1",
- "WP_021526512.1",
- "HCH7488344.1",
- "WP_148044473.1",
- "ANG10160.1",
- "ANG11443.1",
- "HEA0912696.1",
- "ECJ9431290.1",
- "ARF30434.1",
- "ARF37114.1",
- "WP_261627585.1",
- "ANG09566.1",
- "ANG14490.1",
- "WP_240078874.1",
- "WP_032492108.1",
- "ANG25686.1",
- "ANG10517.1",
- "ANG09900.1",
- "ARF31156.1",
- "ANG10619.1",
- "EGO7072685.1",
- "ANG10571.1",
- "ANG10941.1",
- "ANG14225.1",
- "ANG10332.1",
- "ANG18929.1",
- "ANG23932.1",
- "ANG09482.1",
- "ARF44464.1",
- "ANG09950.1",
- "ANG11187.1",
- "ANG16208.1",
- "ANG17092.1",
- "WP_063864863.1",
- "WP_215748091.1",
- "ANG11172.1",
- "ANG14661.1",
- "ANG23677.1",
- "ANG30415.1",
- "ANG29235.1",
- "ANG24073.1",
- "ANG18696.1",
- "ANG10864.1",
- "WP_063864796.1",
- "ANG22868.1",
- "EBP5465763.1",
- "ANG11672.1",
- "ANG31159.1",
- "ARF47333.1",
- "WP_161654968.1"
-]
diff --git a/examples/networks/tem1_accessions.toml b/examples/networks/tem1_accessions.toml
deleted file mode 100644
index 2579cb42..00000000
--- a/examples/networks/tem1_accessions.toml
+++ /dev/null
@@ -1,102 +0,0 @@
-tem1_ids = [
- "EKW4005960.1",
- "EJG7116187.1",
- "AMM70781.1",
- "HBQ2613975.1",
- "WP_000311242.1",
- "EHY2097385.1",
- "HAI5030310.1",
- "WP_000027057.1",
- "HEC0884360.1",
- "HCO3480053.1",
- "WP_215748091.1",
- "ANG14661.1",
- "ANG10160.1",
- "ANG11443.1",
- "ANG18696.1",
- "ANG10864.1",
- "ANG11672.1",
- "WP_161654968.1",
- "WP_261627585.1",
- "ANG09566.1",
- "WP_240078874.1",
- "ANG27598.1",
- "ANG13700.1",
- "ANG10517.1",
- "ANG09900.1",
- "ANG12641.1",
- "ANG10619.1",
- "ANG10571.1",
- "ANG10941.1",
- "ANG14225.1",
- "ANG10332.1",
- "ANG10321.1",
- "WP_117043934.1",
- "ANG09482.1",
- "WP_094320566.1",
- "ANG09950.1",
- "ANG11187.1",
- "ANG16208.1",
- "ANG14159.1",
- "ANG15082.1",
- "WP_223234097.1",
- "ANG09696.1",
- "ANG13191.1",
- "HDN1137928.1",
- "ANG11172.1",
- "WP_015058867.1",
- "HCH7488344.1",
- "ANG29235.1",
- "HEA0912696.1",
- "ANG24073.1",
- "EBP5465763.1",
- "HCQ0586696.1",
- "ANG26441.1",
- "ARF47333.1",
- "ANG32962.1",
- "EHC9934517.1",
- "ANG12753.1",
- "ANG14490.1",
- "ELK1047634.1",
- "ANG09477.1",
- "HBC1239896.1",
- "ANG32427.1",
- "ANG10038.1",
- "ANG15290.1",
- "ANG31811.1",
- "ANG18929.1",
- "ANG24592.1",
- "ANG19121.1",
- "ANG22186.1",
- "ANG17092.1",
- "HAI6872260.1",
- "HAS9376541.1",
- "ANG23677.1",
- "ANG30415.1",
- "ANG12696.1",
- "ANG24706.1",
- "ANG31363.1",
- "ANG25919.1",
- "ANG17861.1",
- "ANG18665.1",
- "ANG31159.1",
- "WP_241312872.1",
- "ANG17982.1",
- "ANG23579.1",
- "EDC4633317.1",
- "ANG23305.1",
- "ANG19419.1",
- "HAW5807676.1",
- "ANG22525.1",
- "WP_249866686.1",
- "ANG24558.1",
- "ANG20310.1",
- "ANG29078.1",
- "ANG24407.1",
- "ANG14724.1",
- "ANG17944.1",
- "MDV1392406.1",
- "ANG25733.1",
- "WP_109791210.1",
- "ANG09890.1",
-]
From aa8641c2a71e64d895d15aba343d9831f17c37cc Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Fri, 23 Feb 2024 11:16:01 +0100
Subject: [PATCH 11/13] added network visualization in 2D and 3D
---
pyeed/network/network.py | 450 ++++++++++++++++++++++++---------------
1 file changed, 279 insertions(+), 171 deletions(-)
diff --git a/pyeed/network/network.py b/pyeed/network/network.py
index 4e1750bf..e5067fa9 100644
--- a/pyeed/network/network.py
+++ b/pyeed/network/network.py
@@ -1,34 +1,50 @@
from typing import List, Optional
import networkx as nx
import plotly.graph_objects as go
+import plotly.express as px
from pydantic import BaseModel, Field
-from pyeed import network
+
from pyeed.core.abstractsequence import AbstractSequence
from pyeed.core.pairwisealignment import PairwiseAlignment
-from pyeed.core.proteininfo import ProteinInfo
-from pyeed.core.alignment import Alignment
-
class SequenceNetwork(BaseModel):
-
- sequences: List[AbstractSequence] = Field(
- ...,
+ """
+ A class representing a sequence network.
+
+ The SequenceNetwork class is used to create and visualize a network of sequences. It takes a list of AbstractSequence objects and a list of PairwiseAlignment objects as input. The network can be visualized in 2D or 3D, with nodes representing sequences and edges representing alignments between sequences.
+
+ Attributes:
+ sequences (Optional[List[AbstractSequence]]): A list of AbstractSequence objects to be compared in the network. Default is an empty list.
+ pairwise_alignments (Optional[List[PairwiseAlignment]]): A list of PairwiseAlignment objects representing the pairwise alignments between sequences. Default is an empty list.
+ weight (Optional[str]): The attribute of the Alignment object to weight the edges in the network. Default is "identity".
+ color (Optional[str]): The attribute of the ProteinInfo object to colorize the nodes in the network. Default is "name".
+ threshold (Optional[float]): Sequences with a weight higher than the threshold are connected in the network. Default is None.
+ label (Optional[str]): The node label in the graph. Default is "name".
+ dimensions (Optional[int]): The dimension of the network graph. Default is 3.
+
+ Methods:
+ graph() -> nx.Graph: Maps properties of alignments to a network graph.
+ visualize(): Visualizes the network graph.
+ """
+
+ sequences: Optional[List[AbstractSequence]] = Field(
+ default=[],
description="List of sequences to be compared",
)
- pairwise_alignments: List[PairwiseAlignment] = Field(
- ...,
+ pairwise_alignments: Optional[List[PairwiseAlignment]] = Field(
+ default=[],
description="List of pairwise alignments",
)
- weight: str = Field(
- ...,
+ weight: Optional[str] = Field(
+ default="identity",
description="Attribute of Alignment to weight the edges",
)
- color: str = Field(
- ...,
+ color: Optional[str] = Field(
+ default="name",
description="Attribute of ProteinInfo to colorize nodes",
)
@@ -37,13 +53,34 @@ class SequenceNetwork(BaseModel):
description="Sequences with a weight higher than the threshold are connected in the network",
)
- label: str = Field(
- ...,
+ label: Optional[str] = Field(
+ default="name",
description="Node label in the graph",
)
+ dimensions: Optional[int] = Field(
+ default=3,
+ description="Dimension of the network graph",
+ )
+
+ @property
def graph(self) -> nx.Graph:
- """Maps properties of alignments to a network graph."""
+ """
+ Maps properties of alignments to a network graph.
+
+ Returns:
+ nx.Graph: The network graph representing the sequence network.
+
+ Raises:
+ ValueError: If the dimensions of the network graph are greater than 3.
+
+ Notes:
+ - The graph is created using the NetworkX library.
+ - Nodes in the graph represent sequences, and edges represent alignments between sequences.
+ - Node attributes include the sequence name, organism, and taxonomy ID.
+ - Edge attributes include the alignment identity, gaps, mismatches, and score.
+ - The graph can be visualized in 2D or 3D using the visualize() method.
+ """
graph = nx.Graph()
# Add nodes and assign node attributes
@@ -52,12 +89,12 @@ def graph(self) -> nx.Graph:
sequence.source_id,
name=sequence.name,
organism=sequence.organism,
+ taxonomy_id=sequence.organism.taxonomy_id,
)
# Add edges and assign edge attributes
if self.threshold != None:
for alignment in self.pairwise_alignments:
- print(alignment.id)
if alignment.identity >= self.threshold:
graph.add_edge(
alignment.input_sequences[0].source_id,
@@ -69,7 +106,6 @@ def graph(self) -> nx.Graph:
)
else:
for alignment in self.pairwise_alignments:
- print()
graph.add_edge(
alignment.input_sequences[0].source_id,
alignment.input_sequences[1].source_id,
@@ -79,158 +115,230 @@ def graph(self) -> nx.Graph:
score=alignment.score,
)
+ if self.dimensions == 2:
+ return self._2d_position_nodes_and_edges(graph)
+ elif self.dimensions == 3:
+ return self._3d_position_nodes_and_edges(graph)
+ else:
+ if self.dimensions > 3:
+ raise ValueError(
+ f"Bruuuhh chill, u visiting from {self.dimensions}D cyberspace? Dimensions must be 2 or 3"
+ )
+
return graph
- # def pairwise_network(
- # alignments: List[Alignment],
- # weight: str = "identity",
- # cutoff: float = None,
- # label: str = "accession_id",
- # color: str = "name",
- # ) -> None:
- # """Takes a list of `Alignment`, constructs a network graph,
- # whereas the edges of the graph are weighted with an attribute of the
- # `Alignment` object. Visualizes the network graph.
-
- # Args:
- # alignments (List[Alignment]): List of pairwise alignments.
- # weight (str, optional): Attribute of `Alignment` to weight the edges.
- # Defaults to "identity".
- # cutoff (float, optional): Sequences with a weight higher than the cutoff are connected
- # in the network. Defaults to None.
- # label (str, optional): Node labe in the graph. Defaults to "accession_id".
- # color (str, optional): Attribute of `ProteinInfo` co colorize nodes. Defaults to "name".
-
- # Raises:
- # ValueError: If 'weights' is not one of "identity", "score", "gaps", or "mismatches".
- # ValueError: If 'label' is not one of "name", "organism", "ec_number",
- # "mol_weight", or "accession_id".
- # """
-
- # # Validate weights
- # weights = ["identity", "score", "gaps", "mismatches"]
- # if weight not in weights:
- # raise ValueError(
- # f"'weight' to parameterize network must be an alignment property ({weights})"
- # )
-
- # # Validate labels
- # labels = ["name", "organism", "ec_number", "mol_weight", "accession_id"]
- # if label not in labels:
- # raise ValueError(
- # f"'label' to parameterize network must be an alignment property ({labels})"
- # )
-
- # graph = construct_network(alignments, cutoff=cutoff)
-
- # graph = position_nodes_and_edges(graph, weight=weight)
-
- # visualize_network(graph, label=label, color=color)
-
-
-# def visualize_network(graph: nx.Graph, label: str, color: str):
-# """Visualizes a network graph."""
-# # TODO: Refactor coloration of nodes
-# # TODO: Add ability to colorize edges
-
-# colors = ["blue", "red", "green", "orange", "purple", "pink", "brown", "yellow"]
-# traces = []
-# # Add edges
-# for edge in graph.edges:
-# traces.append(
-# go.Scatter(
-# x=graph.edges[edge]["x_pos"],
-# y=graph.edges[edge]["y_pos"],
-# mode="lines",
-# line=dict(
-# width=1,
-# # colorscale="YlGnBu",
-# # colorbar=dict(title='Heatmap Colorscale')
-# color="rgba(128, 128, 128, 0.1)",
-# ),
-# hoverinfo="text",
-# text=graph.edges[edge]["gaps"],
-# )
-# )
-
-# # Add nodes
-# color_dict = {}
-# for _, data in graph.nodes(data=True):
-# if data[color] not in color_dict:
-# color_dict[data[color]] = colors[len(color_dict)]
-
-# traces.append(
-# go.Scatter(
-# x=[data["x_pos"]],
-# y=[data["y_pos"]],
-# mode="markers",
-# hoverinfo="text",
-# marker=dict(
-# # showscale=True,
-# # colorscale="Viridis",
-# size=10,
-# # colorbar=dict(thickness=15, title=""),
-# color=color_dict[data[color]],
-# ),
-# text=data[label],
-# )
-# )
-
-# # Plot figure
-# fig = go.Figure(
-# data=traces,
-# layout=go.Layout(
-# plot_bgcolor="white",
-# showlegend=False,
-# hovermode="closest",
-# margin=dict(b=0, l=0, r=0, t=0),
-# ),
-# )
-# fig.update_xaxes(visible=False)
-# fig.update_yaxes(visible=False)
-# print(color_dict)
-
-# fig.show()
-
-
-# def position_nodes_and_edges(graph: nx.Graph, weight: str) -> nx.Graph:
-# """Calculates node positions based on weight metric and
-# adds position information of nodes and edges to the respective
-# entry in the graph."""
-
-# positions = nx.spring_layout(graph, weight=weight)
-
-# # Add node position as coordinates
-# for node in graph.nodes():
-# graph.nodes[node]["x_pos"] = positions[node][0]
-# graph.nodes[node]["y_pos"] = positions[node][1]
-
-# # Add edge positions as coordinates
-# for edge in graph.edges():
-# graph.edges[edge]["x_pos"] = [
-# graph.nodes[edge[0]]["x_pos"],
-# graph.nodes[edge[1]]["x_pos"],
-# ]
-# graph.edges[edge]["y_pos"] = [
-# graph.nodes[edge[0]]["y_pos"],
-# graph.nodes[edge[1]]["y_pos"],
-# ]
-
-# return graph
-
-
-# def _get_unique_sequences(alignments: List[Alignment]) -> List[ProteinInfo]:
-# """Gets unique sequences from a list of alignments."""
-
-# sequence_infos = []
-# added_ids = set()
-# for alignment in alignments:
-# if alignment.reference_seq.source_id not in added_ids:
-# sequence_infos.append(alignment.reference_seq)
-# added_ids.add(alignment.reference_seq.source_id)
-
-# if alignment.query_seq.source_id not in added_ids:
-# sequence_infos.append(alignment.query_seq)
-# added_ids.add(alignment.query_seq.source_id)
-
-# return sequence_infos
+ def visualize(self):
+ """
+ Visualizes the network graph.
+
+ This method visualizes the network graph created by the SequenceNetwork class.
+ It checks the value of the 'dimensions' attribute and calls either the 'visualize_2d_network' or 'visualize_3d_network' method accordingly.
+ If the 'dimensions' attribute is not 2 or 3, it raises a ValueError.
+
+ Returns:
+ None
+
+ Raises:
+ ValueError: If the 'dimensions' attribute is greater than 3.
+
+ Notes:
+ - The visualization is done using the Plotly library.
+ - If the 'dimensions' attribute is 2, the network graph is visualized in 2D.
+ - If the 'dimensions' attribute is 3, the network graph is visualized in 3D.
+ - The visualization includes nodes representing sequences and edges representing alignments between sequences.
+ - The color of the nodes is determined by the 'color' attribute of the SequenceNetwork class.
+ - The hover information for each node includes the sequence name, organism, kingdom, phylum, and source ID.
+ - The visualization is displayed using the Plotly library.
+ """
+
+ if self.dimensions == 2:
+ self.visualize_2d_network()
+ elif self.dimensions == 3:
+ self.visusalize_3d_network()
+ else:
+ if self.dimensions > 3:
+ raise ValueError(
+ f"Dimensions must be 2 or 3 for visualization, not {self.dimensions}"
+ )
+
+ def _2d_position_nodes_and_edges(self, graph: nx.Graph):
+ """Calculates node positions based on weight metric and
+ adds position information of nodes and edges to the respective
+ entry in the graph."""
+
+ positions = nx.spring_layout(graph, weight=self.weight, dim=2, seed=42)
+
+ # Add node position as coordinates
+ for node in graph.nodes():
+ graph.nodes[node]["x_pos"] = positions[node][0]
+ graph.nodes[node]["y_pos"] = positions[node][1]
+
+ # Add edge positions as coordinates
+ for edge in graph.edges():
+ graph.edges[edge]["x_pos"] = [
+ graph.nodes[edge[0]]["x_pos"],
+ graph.nodes[edge[1]]["x_pos"],
+ ]
+ graph.edges[edge]["y_pos"] = [
+ graph.nodes[edge[0]]["y_pos"],
+ graph.nodes[edge[1]]["y_pos"],
+ ]
+
+ return graph
+
+ def _3d_position_nodes_and_edges(self, graph: nx.Graph):
+ """Calculates node positions based on weight metric and
+ adds position information of nodes and edges to the respective
+ entry in the graph."""
+
+ positions = nx.spring_layout(
+ graph, iterations=25, weight=self.weight, dim=3, seed=42
+ )
+
+ # Add node position as coordinates
+ for node in graph.nodes():
+ graph.nodes[node]["x_pos"] = positions[node][0]
+ graph.nodes[node]["y_pos"] = positions[node][1]
+ graph.nodes[node]["z_pos"] = positions[node][2]
+
+ # Add edge positions as coordinates
+ for edge in graph.edges():
+ graph.edges[edge]["x_pos"] = [
+ graph.nodes[edge[0]]["x_pos"],
+ graph.nodes[edge[1]]["x_pos"],
+ ]
+ graph.edges[edge]["y_pos"] = [
+ graph.nodes[edge[0]]["y_pos"],
+ graph.nodes[edge[1]]["y_pos"],
+ ]
+ graph.edges[edge]["z_pos"] = [
+ graph.nodes[edge[0]]["z_pos"],
+ graph.nodes[edge[1]]["z_pos"],
+ ]
+
+ return graph
+
+ def visusalize_3d_network(self):
+ """Visualizes a 3D network graph."""
+
+ traces = []
+ # Add edges
+ # for edge in self.graph.edges:
+ # traces.append(
+ # go.Scatter3d(
+ # x=self.graph.edges[edge]["x_pos"],
+ # y=self.graph.edges[edge]["y_pos"],
+ # z=self.graph.edges[edge]["z_pos"],
+ # mode="lines",
+ # line=dict(
+ # width=1,
+ # color="rgba(128, 128, 128, 0.1)",
+ # ),
+ # hoverinfo="text",
+ # text=self.graph.edges[edge]["gaps"],
+ # )
+ # )
+
+ color_conditions = set([node[self.color] for node in self.graph.nodes.values()])
+ color_dict = dict(
+ zip(color_conditions, self._sample_colorscale(len(color_conditions)))
+ )
+
+ # Add nodes
+ for key, node in self.graph.nodes.items():
+ info = [
+ (
+ node["name"],
+ node["organism"].name,
+ node["organism"].kingdom,
+ node["organism"].phylum,
+ key,
+ )
+ ]
+
+ traces.append(
+ go.Scatter3d(
+ x=[node["x_pos"]],
+ y=[node["y_pos"]],
+ z=[node["z_pos"]],
+ mode="markers",
+ marker=dict(
+ size=7,
+ color=color_dict[node[self.color]],
+ ),
+ text=node["name"],
+ hovertemplate="%{customdata[0]}
Organism: %{customdata[1]}
Kingdom: %{customdata[2]}
Phylum: %{customdata[3]}
Source ID: %{customdata[4]}",
+ customdata=list((info)),
+ )
+ )
+
+ # Plot figure
+ fig = go.Figure(
+ data=traces,
+ layout=go.Layout(
+ plot_bgcolor="white",
+ showlegend=False,
+ hovermode="closest",
+ margin=dict(b=0, l=0, r=0, t=0),
+ ),
+ )
+ fig.update_xaxes(visible=False)
+ fig.update_yaxes(visible=False)
+ fig.update_scenes(xaxis_visible=False, yaxis_visible=False, zaxis_visible=False)
+
+ fig.show()
+
+ def visualize_2d_network(self):
+ """Visualizes a 2D network graph."""
+ traces = []
+
+ # Add nodes
+ color_conditions = set([node[self.color] for node in self.graph.nodes.values()])
+ color_dict = dict(
+ zip(color_conditions, self._sample_colorscale(len(color_conditions)))
+ )
+
+ for key, node in self.graph.nodes.items():
+ info = [
+ (
+ node["name"],
+ node["organism"].name,
+ node["organism"].kingdom,
+ node["organism"].phylum,
+ key,
+ )
+ ]
+
+ traces.append(
+ go.Scatter(
+ x=[node["x_pos"]],
+ y=[node["y_pos"]],
+ mode="markers",
+ marker=dict(
+ size=10,
+ color=color_dict[node[self.color]],
+ ),
+ text=node["name"],
+ hovertemplate="%{customdata[0]}
Organism: %{customdata[1]}
Kingdom: %{customdata[2]}
Phylum: %{customdata[3]}
Source ID: %{customdata[4]}",
+ customdata=list((info)),
+ )
+ )
+
+ # Plot figure
+ fig = go.Figure(
+ data=traces,
+ layout=go.Layout(
+ plot_bgcolor="white",
+ showlegend=False,
+ hovermode="closest",
+ margin=dict(b=0, l=0, r=0, t=0),
+ ),
+ )
+ fig.update_xaxes(visible=False)
+ fig.update_yaxes(visible=False)
+
+ fig.show()
+
+ @staticmethod
+ def _sample_colorscale(size: int) -> List[str]:
+ return px.colors.sample_colorscale("viridis", [i / size for i in range(size)])
From ad63cafb717a638b4f8900a79400cf6ec03a9b1b Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Fri, 23 Feb 2024 11:16:08 +0100
Subject: [PATCH 12/13] import
---
pyeed/network/__init__.py | 1 +
1 file changed, 1 insertion(+)
diff --git a/pyeed/network/__init__.py b/pyeed/network/__init__.py
index e69de29b..f0e0d1ca 100644
--- a/pyeed/network/__init__.py
+++ b/pyeed/network/__init__.py
@@ -0,0 +1 @@
+from .network import SequenceNetwork
From 553d93a6c9d889dee772c977b088bf9ccaf47497 Mon Sep 17 00:00:00 2001
From: haeussma <83341109+haeussma@users.noreply.github.com>
Date: Fri, 23 Feb 2024 11:16:18 +0100
Subject: [PATCH 13/13] added network documentation
---
docs/quick_start/networks.md | 83 ++++++++++++++++++++++++++++++++++++
1 file changed, 83 insertions(+)
diff --git a/docs/quick_start/networks.md b/docs/quick_start/networks.md
index e69de29b..e73d798f 100644
--- a/docs/quick_start/networks.md
+++ b/docs/quick_start/networks.md
@@ -0,0 +1,83 @@
+# Creating Sequence Networks
+
+A `SequenceNetwork` is created using a list of `PairwiseAlignment` objects, and a list of `AbstractSequences`. Additionally, the way the network is constructed is influenced by the `weight` and `threshold` attributes. The `weight` determines which attribute of the `PairwiseAlignment` object is used to calculate the distance between the sequences of the network. The `threshold` determines the minimum value of the `weight` attribute for an edge to be created. Furthermore, a `color` can be determined based on the attributes of an `AbstractSequence` object in which the nodes of the network will be colored.
+
+## Visualization
+
+=== "2D"
+
+ ```py
+ from pyeed.core import ProteinInfo, Alignment
+ from pyeed.aligners import PairwiseAligner
+ from pyeed.network import SequenceNetwork
+
+ # Accessions from different methionine adenyltransferases
+ mat_accessions = [
+ "MBP1912539.1",
+ "SEV92896.1",
+ "MBO8174569.1",
+ "WP_042680787.1",
+ "NPA47376.1",
+ "WP_167889085.1",
+ "WP_048165429.1",
+ "ACS90033.1",
+ ]
+ mats = ProteinInfo.from_ncbi(mat_accessions)
+
+ # Create pairwise alignments between all sequences
+ alignments = Alignment.from_sequences(mats, aligner=PairwiseAligner)
+
+ # Create a network
+ network = SequenceNetwork(
+ sequences=mats,
+ pairwise_alignments=alignments,
+ weight="identity",
+ threshold=0.9,
+ dimensions=2,
+ color="taxonomy_id",
+ )
+
+ # Visualize the network
+ network.visualize()
+ ```
+
+=== "3D"
+
+ ```py
+ from pyeed.core import ProteinInfo, Alignment
+ from pyeed.aligners import PairwiseAligner
+ from pyeed.network import SequenceNetwork
+
+ # Accessions from different methionine adenyltransferases
+ mat_accessions = [
+ "MBP1912539.1",
+ "SEV92896.1",
+ "MBO8174569.1",
+ "WP_042680787.1",
+ "NPA47376.1",
+ "WP_167889085.1",
+ "WP_048165429.1",
+ "ACS90033.1",
+ ]
+ mats = ProteinInfo.from_ncbi(mat_accessions)
+
+ # Create pairwise alignments between all sequences
+ alignments = Alignment.from_sequences(mats, aligner=PairwiseAligner)
+
+ # Create a network
+ network = SequenceNetwork(
+ sequences=mats,
+ pairwise_alignments=alignments,
+ weight="identity",
+ threshold=0.9,
+ dimensions=3,
+ color="taxonomy_id",
+ )
+
+ # Visualize the network
+ network.visualize()
+ ```
+
+## Network Analysis
+
+Upon the `SequenceNetwork` is instantiated the `graph` property is created. This property is a `networkx` graph object that can be used to perform network analysis. For example, the `degree()` method can be used to calculate the degree of each node in the network.