diff --git a/DockerfileJupyter b/DockerfileJupyter
index 1fc031d01415..cab96b81cebe 100644
--- a/DockerfileJupyter
+++ b/DockerfileJupyter
@@ -47,6 +47,12 @@ RUN chmod -R 777 ${WORK}
 
 RUN pip install clr-loader
 
+# Work around for https://github.com/pythonnet/clr-loader/issues/8
+COPY fix_ffi_mono.py /opt/miniconda3/lib/python3.6/site-packages/clr_loader/ffi/mono.py
+COPY fix_mono.py /opt/miniconda3/lib/python3.6/site-packages/clr_loader/mono.py
+ENV LD_LIBRARY_PATH=/lib/
+RUN ln -s /lib/x86_64-linux-gnu/libc.so.6 /lib/x86_64-linux-gnu/libc.so
+
 EXPOSE 8888
 WORKDIR $WORK
 
diff --git a/Research/fix_ffi_mono.py b/Research/fix_ffi_mono.py
new file mode 100644
index 000000000000..6719f3437e27
--- /dev/null
+++ b/Research/fix_ffi_mono.py
@@ -0,0 +1,30 @@
+# flake8: noqa
+
+cdef = []
+
+cdef.append(
+    """
+typedef struct _MonoDomain MonoDomain;
+typedef struct _MonoAssembly MonoAssembly;
+typedef struct _MonoImage MonoImage;
+typedef struct _MonoMethodDesc MonoMethodDesc;
+typedef struct _MonoMethod MonoMethod;
+typedef struct _MonoObject MonoObject;
+
+MonoDomain* mono_jit_init(const char *root_domain_name);
+void mono_jit_cleanup(MonoDomain *domain);
+MonoAssembly* mono_domain_assembly_open(MonoDomain *domain, const char *name);
+MonoImage* mono_assembly_get_image(MonoAssembly *assembly);
+
+void mono_config_parse(const char* path);
+void mono_domain_set_config(MonoDomain *domain, const char *base_dir, const char *config_file_name);
+
+MonoMethodDesc* mono_method_desc_new(const char* name, bool include_namespace);
+MonoMethod* mono_method_desc_search_in_image(MonoMethodDesc *method_desc, MonoImage *image);
+void mono_method_desc_free(MonoMethodDesc *method_desc);
+
+MonoObject* mono_runtime_invoke(MonoMethod *method, void *obj, void **params, MonoObject **exc);
+
+void* mono_object_unbox(MonoObject *object);
+"""
+)
\ No newline at end of file
diff --git a/Research/fix_mono.py b/Research/fix_mono.py
new file mode 100644
index 000000000000..ca8c88ab196a
--- /dev/null
+++ b/Research/fix_mono.py
@@ -0,0 +1,112 @@
+import atexit
+
+from .ffi import load_mono, ffi
+
+
+__all__ = ["Mono"]
+
+
+_MONO = None
+_ROOT_DOMAIN = None
+
+
+class Mono:
+    def __init__(self, libmono, domain=None, config_file=None):
+        self._assemblies = {}
+
+        initialize(config_file=config_file, libmono=libmono)
+
+        if domain is None:
+            self._domain = _ROOT_DOMAIN
+        else:
+            raise NotImplementedError
+
+    def get_callable(self, assembly_path, typename, function):
+        assembly = self._assemblies.get(assembly_path)
+        if not assembly:
+            assembly = _MONO.mono_domain_assembly_open(
+                self._domain, assembly_path.encode("utf8")
+            )
+            _check_result(assembly, f"Unable to load assembly {assembly_path}")
+            self._assemblies[assembly_path] = assembly
+
+        image = _MONO.mono_assembly_get_image(assembly)
+        _check_result(image, "Unable to load image from assembly")
+
+        desc = MethodDesc(typename, function)
+        method = desc.search(image)
+        _check_result(
+            method, f"Could not find method {typename}.{function} in assembly"
+        )
+
+        return MonoMethod(method)
+
+
+class MethodDesc:
+    def __init__(self, typename, function):
+        self._desc = f"{typename}:{function}"
+        self._ptr = _MONO.mono_method_desc_new(
+            self._desc.encode("utf8"), 1  # include_namespace
+        )
+
+    def search(self, image):
+        return _MONO.mono_method_desc_search_in_image(self._ptr, image)
+
+    def __del__(self):
+        if _MONO:
+            _MONO.mono_method_desc_free(self._ptr)
+
+
+class MonoMethod:
+    def __init__(self, ptr):
+        self._ptr = ptr
+
+    def __call__(self, ptr, size):
+        exception = ffi.new("MonoObject**")
+        params = ffi.new("void*[2]")
+
+        # Keep these alive until the function is called by assigning them locally
+        ptr_ptr = ffi.new("void**", ptr)
+        size_ptr = ffi.new("int32_t*", size)
+
+        params[0] = ptr_ptr
+        params[1] = size_ptr
+
+        res = _MONO.mono_runtime_invoke(self._ptr, ffi.NULL, params, exception)
+        _check_result(res, "Failed to call method")
+
+        unboxed = ffi.cast("int32_t*", _MONO.mono_object_unbox(res))
+        _check_result(unboxed, "Failed to convert result to int")
+
+        return unboxed[0]
+
+
+def initialize(config_file: str, libmono: str) -> None:
+    global _MONO, _ROOT_DOMAIN
+    if _MONO is None:
+        _MONO = load_mono(libmono)
+
+        if config_file is None:
+            config_bytes = ffi.NULL
+        else:
+            config_bytes = config_file.encode("utf8")
+
+        _ROOT_DOMAIN = _MONO.mono_jit_init(b"clr_loader")
+
+        _MONO.mono_domain_set_config(_ROOT_DOMAIN, b"/etc/mono/", b"config");
+
+        _check_result(_ROOT_DOMAIN, "Failed to initialize Mono")
+        atexit.register(_release)
+
+
+def _release():
+    global _MONO, _ROOT_DOMAIN
+    if _ROOT_DOMAIN is not None and _MONO is not None:
+        _MONO.mono_jit_cleanup(_ROOT_DOMAIN)
+        _MONO = None
+        _ROOT_DOMAIN = None
+
+
+def _check_result(res, msg):
+    if res == ffi.NULL or not res:
+        raise RuntimeError(msg)
\ No newline at end of file