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Mutect2 vcfs improperly formatted #699

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drejom opened this issue Dec 12, 2018 · 0 comments
Closed

Mutect2 vcfs improperly formatted #699

drejom opened this issue Dec 12, 2018 · 0 comments
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@drejom
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drejom commented Dec 12, 2018

Describe the bug
A clear and concise description of what the bug is.
Mutect2 vcfs missing DP in the FORMAT column (present only in INFO column). This is fixed in gatk version >4.0.9.0 (Sarek release 2.1.1 uses gatk 4.0.6.0)

To Reproduce
Steps to reproduce the behavior:

  1. Command line '...'
    somaticVC.nf --tools mutect2

  2. See error Please provide your error message
    No error is reported

Expected behavior
A clear and concise description of what you expected to happen.
DP should be reported in the FORMAT field. Makes VCFs produced by Sarek 2.1.0 incompatible with some R packages, eg VariantAnnotion and seqCAT

System (please complete the following information):

  • Hardware: [e.g. HPC, Desktop, Cloud...]
  • Executor: [e.g. slurm, local, awsbatch...]
  • OS: [e.g. CentOS Linux, macOS, Linux Mint...]
  • Version [e.g. 7, 10.13.6, 18.3...]

Nextflow (please complete the following information):

  • Version: [e.g. 0.31.0]

Container engine (please complete the following information):

  • Engine: [e.g. Conda, Docker or Singularity]
  • version: [e.g. 1.0.0]
    Singularity

Container (please complete the following information):

  • tag: [e.g. 1.0.0]
    2.1.1
    Sarek (please complete the following information):
  • version: [e.g. 2.1.0]
    2.1.1

Additional context
Add any other context about the problem here.

@szilvajuhos szilvajuhos self-assigned this Dec 13, 2018
@maxulysse maxulysse mentioned this issue Dec 13, 2018
4 tasks
@drejom drejom closed this as completed Dec 21, 2018
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