diff --git a/packages/block-library/src/separator/block.json b/packages/block-library/src/separator/block.json
index 784146a733fbde..784f34adeff602 100644
--- a/packages/block-library/src/separator/block.json
+++ b/packages/block-library/src/separator/block.json
@@ -16,7 +16,10 @@
 	},
 	"supports": {
 		"anchor": true,
-		"align": [ "center", "wide", "full" ]
+		"align": [ "center", "wide", "full" ],
+		"spacing": {
+			"margin": [ "top", "bottom" ]
+		}
 	},
 	"styles": [
 		{ "name": "default", "label": "Default", "isDefault": true },
diff --git a/packages/block-library/src/separator/edit.native.js b/packages/block-library/src/separator/edit.native.js
new file mode 100644
index 00000000000000..33a7207a3bf7d9
--- /dev/null
+++ b/packages/block-library/src/separator/edit.native.js
@@ -0,0 +1,48 @@
+/**
+ * WordPress dependencies
+ */
+import { withColors, useBlockProps } from '@wordpress/block-editor';
+import { HorizontalRule, useConvertUnitToMobile } from '@wordpress/components';
+
+/**
+ * Internal dependencies
+ */
+import SeparatorSettings from './separator-settings';
+import { MARGIN_CONSTRAINTS, parseUnit } from './shared';
+
+function SeparatorEdit( props ) {
+	const {
+		color,
+		attributes: { style },
+	} = props;
+
+	const { top, bottom } = style?.spacing?.margin || {};
+	const marginUnit = parseUnit( top || bottom );
+
+	const convertedMarginTop = useConvertUnitToMobile(
+		parseFloat( top || 0 ) || MARGIN_CONSTRAINTS[ marginUnit ].min,
+		marginUnit
+	);
+
+	const convertedMarginBottom = useConvertUnitToMobile(
+		parseFloat( bottom || 0 ) || MARGIN_CONSTRAINTS[ marginUnit ].min,
+		marginUnit
+	);
+
+	return (
+		<>
+			<HorizontalRule
+				{ ...useBlockProps() }
+				style={ {
+					backgroundColor: color.color,
+					color: color.color,
+					marginBottom: convertedMarginBottom,
+					marginTop: convertedMarginTop,
+				} }
+			/>
+			<SeparatorSettings { ...props } />
+		</>
+	);
+}
+
+export default withColors( 'color', { textColor: 'color' } )( SeparatorEdit );
diff --git a/packages/block-library/src/separator/separator-settings.native.js b/packages/block-library/src/separator/separator-settings.native.js
index d2bdd8ef6443a3..8c238b28648f54 100644
--- a/packages/block-library/src/separator/separator-settings.native.js
+++ b/packages/block-library/src/separator/separator-settings.native.js
@@ -1,3 +1,113 @@
-// Mobile has no separator settings at this time, so render nothing
-const SeparatorSettings = () => null;
+/**
+ * WordPress dependencies
+ */
+import { InspectorControls, PanelColorSettings } from '@wordpress/block-editor';
+import {
+	PanelBody,
+	UnitControl,
+	__experimentalUseCustomUnits as useCustomUnits,
+} from '@wordpress/components';
+import { __ } from '@wordpress/i18n';
+
+/**
+ * Internal dependencies
+ */
+import { MARGIN_CONSTRAINTS, parseUnit } from './shared';
+
+const SeparatorSettings = ( {
+	color,
+	setColor,
+	attributes: { style },
+	setAttributes,
+} ) => {
+	const units = useCustomUnits( {
+		availableUnits: [ 'px', 'em', 'rem' ],
+		defaultValues: { px: '0', em: '0', rem: '0' },
+	} );
+
+	const { top, bottom } = style?.spacing?.margin || {};
+	const topUnit = parseUnit( top );
+	const bottomUnit = parseUnit( bottom );
+	const topValue = top
+		? parseFloat( top )
+		: MARGIN_CONSTRAINTS[ topUnit ].min;
+	const bottomValue = bottom
+		? parseFloat( bottom )
+		: MARGIN_CONSTRAINTS[ bottomUnit ].min;
+
+	const updateMargins = ( margins ) => {
+		setAttributes( {
+			style: {
+				...style,
+				spacing: {
+					...style?.spacing,
+					margin: margins,
+				},
+			},
+		} );
+	};
+
+	const createHandleMarginChange = ( side, unit ) => ( value ) => {
+		updateMargins( {
+			...style?.spacing?.margin,
+			[ side ]: `${ value }${ unit }`,
+		} );
+	};
+
+	const onUnitChange = ( unit ) => {
+		updateMargins( {
+			top: MARGIN_CONSTRAINTS[ unit ].default,
+			bottom: MARGIN_CONSTRAINTS[ unit ].default,
+		} );
+	};
+
+	return (
+		<InspectorControls>
+			<PanelColorSettings
+				title={ __( 'Color settings' ) }
+				colorSettings={ [
+					{
+						value: color.color,
+						onChange: setColor,
+						label: __( 'Color' ),
+					},
+				] }
+			/>
+			<PanelBody title={ __( 'Separator settings' ) }>
+				<UnitControl
+					label={ __( 'Top margin' ) }
+					key={ `separator-top-margin-${ bottomUnit }` }
+					min={ MARGIN_CONSTRAINTS[ topUnit ].min }
+					max={ MARGIN_CONSTRAINTS[ topUnit ].max }
+					value={ topValue || MARGIN_CONSTRAINTS[ topUnit ].min }
+					unit={ topUnit }
+					units={ units }
+					onChange={ createHandleMarginChange( 'top', topUnit ) }
+					onUnitChange={ onUnitChange }
+					decimalNum={ 1 }
+					step={ topUnit === 'px' ? 1 : 0.1 }
+				/>
+				<UnitControl
+					label={ __( 'Bottom margin' ) }
+					key={ `separator-bottom-margin-${ bottomUnit }` }
+					min={ MARGIN_CONSTRAINTS[ bottomUnit ].min }
+					max={ MARGIN_CONSTRAINTS[ bottomUnit ].max }
+					value={
+						bottomValue || MARGIN_CONSTRAINTS[ bottomUnit ].min
+					}
+					unit={ bottomUnit }
+					units={ units }
+					onChange={ createHandleMarginChange(
+						'bottom',
+						bottomUnit
+					) }
+					onUnitChange={ onUnitChange }
+					decimalNum={ 1 }
+					step={ bottomUnit === 'px' ? 1 : 0.1 }
+				/>
+			</PanelBody>
+		</InspectorControls>
+	);
+};
+
 export default SeparatorSettings;
diff --git a/packages/block-library/src/separator/shared.js b/packages/block-library/src/separator/shared.js
new file mode 100644
index 00000000000000..6deba13b6d86e6
--- /dev/null
+++ b/packages/block-library/src/separator/shared.js
@@ -0,0 +1,47 @@
+// Separator margin related constants.
+export const MIN_PX_MARGIN = 15;
+export const MIN_EM_MARGIN = 0.75;
+export const MIN_REM_MARGIN = 0.7;
+export const MAX_PX_MARGIN = 300;
+export const MAX_EM_MARGIN = 20;
+export const MAX_REM_MARGIN = 20;
+
+/**
+ * Separator margin constraints for available CSS units.
+ */
+export const MARGIN_CONSTRAINTS = {
+	px: {
+		min: MIN_PX_MARGIN,
+		max: MAX_PX_MARGIN,
+		default: `${ MIN_PX_MARGIN }px`,
+	},
+	em: {
+		min: MIN_EM_MARGIN,
+		max: MAX_EM_MARGIN,
+		default: '1em',
+	},
+	rem: {
+		min: MIN_REM_MARGIN,
+		max: MAX_REM_MARGIN,
+		default: '1rem',
+	},
+};
+
+/**
+ * Extracts CSS unit from string.
+ *
+ * @param { string } cssValue CSS string containing unit and value.
+ * @return { string }         CSS unit. Defaults to 'px'.
+ */
+export const parseUnit = ( cssValue ) => {
+	if ( ! cssValue ) {
+		return 'px';
+	}
+
+	const matches = cssValue.trim().match( /[\d.\-+]*\s*([a-zA-Z]*)$/ );
+	if ( ! matches ) {
+		return 'px';
+	}
+	const [ , unit ] = matches;
+	return ( unit || 'px' ).toLowerCase();
+};
diff --git a/packages/primitives/src/horizontal-rule/index.native.js b/packages/primitives/src/horizontal-rule/index.native.js
index 853b57e76d0c1a..3d338ad7d4ba7f 100644
--- a/packages/primitives/src/horizontal-rule/index.native.js
+++ b/packages/primitives/src/horizontal-rule/index.native.js
@@ -2,6 +2,7 @@
  * External dependencies
  */
 import Hr from 'react-native-hr';
+import { View } from 'react-native';
 
 /**
  * WordPress dependencies
@@ -13,16 +14,30 @@ import { withPreferredColorScheme } from '@wordpress/compose';
  */
 import styles from './styles.scss';
 
-const HR = ( { getStylesFromColorScheme, ...props } ) => {
+const HR = ( { getStylesFromColorScheme, style, ...props } ) => {
 	const lineStyle = getStylesFromColorScheme( styles.line, styles.lineDark );
+	const customBackground = style?.backgroundColor
+		? { backgroundColor: style.backgroundColor }
+		: {};
 
 	return (
-		<Hr
-			{ ...props }
-			lineStyle={ [ lineStyle, props.lineStyle ] }
-			marginLeft={ 0 }
-			marginRight={ 0 }
-		/>
+		<View
+			style={ {
+				marginTop: style?.marginTop,
+				marginBottom: style?.marginBottom,
+			} }
+		>
+			<Hr
+				{ ...props }
+				lineStyle={ {
+					...lineStyle,
+					...props.lineStyle,
+					...customBackground,
+				} }
+				marginLeft={ 0 }
+				marginRight={ 0 }
+			/>
+		</View>
 	);
 };