diff --git a/Lib/subprocess.py b/Lib/subprocess.py
index c0bda96cbc0339..5bbeba47a37432 100644
--- a/Lib/subprocess.py
+++ b/Lib/subprocess.py
@@ -218,22 +218,38 @@ def __repr__(self):
         _PopenSelector = selectors.SelectSelector
 
 
-# This lists holds Popen instances for which the underlying process had not
-# exited at the time its __del__ method got called: those processes are wait()ed
-# for synchronously from _cleanup() when a new Popen object is created, to avoid
-# zombie processes.
-_active = []
-
-def _cleanup():
-    for inst in _active[:]:
-        res = inst._internal_poll(_deadstate=sys.maxsize)
-        if res is not None:
-            try:
-                _active.remove(inst)
-            except ValueError:
-                # This can happen if two threads create a new Popen instance.
-                # It's harmless that it was already removed, so ignore.
-                pass
+if _mswindows:
+    # On Windows we just need to close `Popen._handle` when we no longer need
+    # it, so that the kernel can free it. `Popen._handle` gets closed
+    # implicitly when the `Popen` instance is finalized (see `Handle.__del__`,
+    # which is calling `CloseHandle` as requested in [1]), so there is nothing
+    # for `_cleanup` to do.
+    #
+    # [1] https://docs.microsoft.com/en-us/windows/desktop/ProcThread/
+    # creating-processes
+    _active = None
+
+    def _cleanup():
+        pass
+else:
+    # This lists holds Popen instances for which the underlying process had not
+    # exited at the time its __del__ method got called: those processes are
+    # wait()ed for synchronously from _cleanup() when a new Popen object is
+    # created, to avoid zombie processes.
+    _active = []
+
+    def _cleanup():
+        if _active is None:
+            return
+        for inst in _active[:]:
+            res = inst._internal_poll(_deadstate=sys.maxsize)
+            if res is not None:
+                try:
+                    _active.remove(inst)
+                except ValueError:
+                    # This can happen if two threads create a new Popen instance.
+                    # It's harmless that it was already removed, so ignore.
+                    pass
 
 PIPE = -1
 STDOUT = -2
diff --git a/Lib/test/test_subprocess.py b/Lib/test/test_subprocess.py
index 97d21904b9cecf..6b8acb258ee36e 100644
--- a/Lib/test/test_subprocess.py
+++ b/Lib/test/test_subprocess.py
@@ -59,10 +59,14 @@ def setUp(self):
         support.reap_children()
 
     def tearDown(self):
-        for inst in subprocess._active:
-            inst.wait()
-        subprocess._cleanup()
-        self.assertFalse(subprocess._active, "subprocess._active not empty")
+        if not mswindows:
+            # subprocess._active is not used on Windows and is set to None.
+            for inst in subprocess._active:
+                inst.wait()
+            subprocess._cleanup()
+            self.assertFalse(
+                subprocess._active, "subprocess._active not empty"
+            )
         self.doCleanups()
         support.reap_children()
 
@@ -2679,8 +2683,12 @@ def test_zombie_fast_process_del(self):
         with support.check_warnings(('', ResourceWarning)):
             p = None
 
-        # check that p is in the active processes list
-        self.assertIn(ident, [id(o) for o in subprocess._active])
+        if mswindows:
+            # subprocess._active is not used on Windows and is set to None.
+            self.assertIsNone(subprocess._active)
+        else:
+            # check that p is in the active processes list
+            self.assertIn(ident, [id(o) for o in subprocess._active])
 
     def test_leak_fast_process_del_killed(self):
         # Issue #12650: on Unix, if Popen.__del__() was called before the
@@ -2701,8 +2709,12 @@ def test_leak_fast_process_del_killed(self):
             p = None
 
         os.kill(pid, signal.SIGKILL)
-        # check that p is in the active processes list
-        self.assertIn(ident, [id(o) for o in subprocess._active])
+        if mswindows:
+            # subprocess._active is not used on Windows and is set to None.
+            self.assertIsNone(subprocess._active)
+        else:
+            # check that p is in the active processes list
+            self.assertIn(ident, [id(o) for o in subprocess._active])
 
         # let some time for the process to exit, and create a new Popen: this
         # should trigger the wait() of p
@@ -2714,7 +2726,11 @@ def test_leak_fast_process_del_killed(self):
                 pass
         # p should have been wait()ed on, and removed from the _active list
         self.assertRaises(OSError, os.waitpid, pid, 0)
-        self.assertNotIn(ident, [id(o) for o in subprocess._active])
+        if mswindows:
+            # subprocess._active is not used on Windows and is set to None.
+            self.assertIsNone(subprocess._active)
+        else:
+            self.assertNotIn(ident, [id(o) for o in subprocess._active])
 
     def test_close_fds_after_preexec(self):
         fd_status = support.findfile("fd_status.py", subdir="subprocessdata")
diff --git a/Misc/NEWS.d/next/Windows/2019-06-25-04-15-22.bpo-37380.tPxjuz.rst b/Misc/NEWS.d/next/Windows/2019-06-25-04-15-22.bpo-37380.tPxjuz.rst
new file mode 100644
index 00000000000000..facce27954a633
--- /dev/null
+++ b/Misc/NEWS.d/next/Windows/2019-06-25-04-15-22.bpo-37380.tPxjuz.rst
@@ -0,0 +1,2 @@
+Don't collect unfinished processes with ``subprocess._active`` on Windows to
+cleanup later. Patch by Ruslan Kuprieiev.