test.out

Func_id,Func_name,MMB1,MMB2,MSB1,MSB2,Sum
COG0001,H,Glutamate-1-semialdehyde aminotransferase,0,10,29,33,72
COG0002,E,Acetylglutamate semialdehyde dehydrogenase,0,2,22,11,35
COG0003,P,Oxyanion-translocating ATPase,0,5,3,2,10
COG0004,P,Ammonia permease,5,4,20,10,39
COG0005,F,Purine nucleoside phosphorylase,0,3,16,11,30
COG0006,E,Xaa-Pro aminopeptidase,0,12,23,19,54
COG0007,H,Uroporphyrinogen-III methylase,1,6,13,6,26
COG0008,J,Glutamyl- and glutaminyl-tRNA synthetases,0,6,27,20,53
COG0009,J,Putative translation factor (SUA5),1,4,13,4,22
COG0010,E,"Arginase/agmatinase/formimionoglutamate hydrolase, arginase family",2,11,57,15,85
COG0011,S,Uncharacterized conserved protein,0,0,14,2,16
COG0012,J,"Predicted GTPase, probable translation factor",4,2,34,12,52
COG0013,J,Alanyl-tRNA synthetase,1,7,36,18,62
COG0014,E,Gamma-glutamyl phosphate reductase,0,2,16,5,23
COG0015,F,Adenylosuccinate lyase,2,9,39,16,66
COG0016,J,Phenylalanyl-tRNA synthetase alpha subunit,0,5,27,15,47
COG0017,J,Aspartyl/asparaginyl-tRNA synthetases,3,3,8,12,26
COG0018,J,Arginyl-tRNA synthetase,1,6,15,15,37
COG0019,E,Diaminopimelate decarboxylase,3,17,33,15,68
COG0020,I,Undecaprenyl pyrophosphate synthase,0,5,34,6,45
COG0021,G,Transketolase,2,7,12,17,38
COG0022,C,"Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit",2,10,47,27,86
COG0023,J,Translation initiation factor 1 (eIF-1/SUI1) and related proteins,0,1,0,2,3
COG0024,J,Methionine aminopeptidase,0,2,39,13,54
COG0025,P,NhaP-type Na+/H+ and K+/H+ antiporters,0,1,16,4,21
COG0026,F,Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase),0,2,17,6,25
COG0027,F,Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase),0,2,0,0,2
COG0028,EH,"Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]",7,7,151,52,217
COG0029,H,Aspartate oxidase,4,2,21,12,39
COG0030,J,Dimethyladenosine transferase (rRNA methylation),0,2,14,11,27
COG0031,E,Cysteine synthase,0,14,56,20,90
COG0033,G,Phosphoglucomutase,0,2,14,5,21
COG0034,F,Glutamine phosphoribosylpyrophosphate amidotransferase,6,4,22,16,48
COG0035,F,Uracil phosphoribosyltransferase,0,2,20,1,23
COG0036,G,Pentose-5-phosphate-3-epimerase,0,4,24,9,37
COG0037,D,Predicted ATPase of the PP-loop superfamily implicated in cell cycle control,3,2,15,8,28
COG0038,P,Chloride channel protein EriC,0,1,0,8,9
COG0039,C,Malate/lactate dehydrogenases,2,3,4,6,15
COG0040,E,ATP phosphoribosyltransferase,4,1,16,11,32
COG0041,F,Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase,0,3,23,11,37
COG0042,J,tRNA-dihydrouridine synthase,3,6,16,1,26
COG0043,H,3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases,3,7,1,36,47
COG0044,F,Dihydroorotase and related cyclic amidohydrolases,1,15,33,21,70
COG0045,C,"Succinyl-CoA synthetase, beta subunit",0,2,19,12,33
COG0046,F,"Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain",5,5,40,16,66
COG0047,F,"Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain",0,3,16,6,25
COG0048,J,Ribosomal protein S12,3,1,17,5,26
COG0049,J,Ribosomal protein S7,0,1,16,4,21
COG0050,J,GTPases - translation elongation factors,16,11,23,8,58
COG0051,J,Ribosomal protein S10,2,1,15,4,22
COG0052,J,Ribosomal protein S2,2,1,18,13,34
COG0053,P,Predicted Co/Zn/Cd cation transporters,1,3,22,22,48
COG0054,H,Riboflavin synthase beta-chain,0,3,27,7,37
COG0055,C,"F0F1-type ATP synthase, beta subunit",4,3,13,7,27
COG0056,C,"F0F1-type ATP synthase, alpha subunit",3,5,17,7,32
COG0057,G,Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase,1,15,29,10,55
COG0058,G,Glucan phosphorylase,1,6,0,24,31
COG0059,EH,Ketol-acid reductoisomerase,0,1,13,5,19
COG0060,J,Isoleucyl-tRNA synthetase,4,7,37,22,70
COG0061,G,Predicted sugar kinase,0,2,17,6,25
COG0062,S,Uncharacterized conserved protein,0,2,0,2,4
COG0063,G,Predicted sugar kinase,2,2,12,6,22
COG0064,J,Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog),0,5,18,12,35
COG0065,E,3-isopropylmalate dehydratase large subunit,4,4,29,14,51
COG0066,E,3-isopropylmalate dehydratase small subunit,0,1,17,7,25
COG0067,E,Glutamate synthase domain 1,0,2,15,5,22
COG0068,O,Hydrogenase maturation factor,0,2,1,7,10
COG0069,E,Glutamate synthase domain 2,3,4,38,4,49
COG0070,E,Glutamate synthase domain 3,2,4,0,2,8
COG0071,O,Molecular chaperone (small heat shock protein),2,10,0,31,43
COG0072,J,Phenylalanyl-tRNA synthetase beta subunit,1,8,30,15,54
COG0073,R,EMAP domain,0,3,10,3,16
COG0074,C,"Succinyl-CoA synthetase, alpha subunit",2,2,15,7,26
COG0075,E,Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase,0,6,32,27,65
COG0076,E,Glutamate decarboxylase and related PLP-dependent proteins,1,3,11,12,27
COG0077,E,Prephenate dehydratase,0,5,31,5,41
COG0078,E,Ornithine carbamoyltransferase,0,6,9,10,25
COG0079,E,Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase,0,11,40,18,69
COG0080,J,Ribosomal protein L11,1,0,15,3,19
COG0081,J,Ribosomal protein L1,3,3,18,9,33
COG0082,E,Chorismate synthase,2,5,20,11,38
COG0083,E,Homoserine kinase,0,0,26,5,31
COG0084,L,Mg-dependent DNase,0,2,9,7,18
COG0085,K,"DNA-directed RNA polymerase, beta subunit/140 kD subunit",10,10,26,27,73
COG0086,K,"DNA-directed RNA polymerase, beta' subunit/160 kD subunit",16,3,25,21,65
COG0087,J,Ribosomal protein L3,0,2,23,4,29
COG0088,J,Ribosomal protein L4,1,1,18,3,23
COG0089,J,Ribosomal protein L23,5,4,17,5,31
COG0090,J,Ribosomal protein L2,6,2,23,5,36
COG0091,J,Ribosomal protein L22,5,2,17,3,27
COG0092,J,Ribosomal protein S3,2,5,20,8,35
COG0093,J,Ribosomal protein L14,2,3,17,6,28
COG0094,J,Ribosomal protein L5,2,1,17,7,27
COG0095,H,Lipoate-protein ligase A,0,1,26,0,27
COG0096,J,Ribosomal protein S8,3,4,18,6,31
COG0097,J,Ribosomal protein L6P/L9E,1,3,16,5,25
COG0098,J,Ribosomal protein S5,3,2,23,7,35
COG0099,J,Ribosomal protein S13,3,2,8,3,16
COG0100,J,Ribosomal protein S11,1,1,9,3,14
COG0101,J,Pseudouridylate synthase,1,3,6,4,14
COG0102,J,Ribosomal protein L13,1,3,13,8,25
COG0103,J,Ribosomal protein S9,0,1,9,6,16
COG0104,F,Adenylosuccinate synthase,4,3,31,12,50
COG0105,F,Nucleoside diphosphate kinase,0,2,17,2,21
COG0106,E,Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase,0,2,16,5,23
COG0107,E,Imidazoleglycerol-phosphate synthase,0,3,18,3,24
COG0108,H,"3,4-dihydroxy-2-butanone 4-phosphate synthase",0,1,14,8,23
COG0109,O,Polyprenyltransferase (cytochrome oxidase assembly factor),0,5,9,6,20
COG0110,R,Acetyltransferase (isoleucine patch superfamily),0,2,61,5,68
COG0111,HE,Phosphoglycerate dehydrogenase and related dehydrogenases,2,8,90,19,119
COG0112,E,Glycine/serine hydroxymethyltransferase,2,10,13,13,38
COG0113,H,Delta-aminolevulinic acid dehydratase,0,3,23,10,36
COG0114,C,Fumarase,0,3,21,6,30
COG0115,EH,Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase,3,7,32,19,61
COG0116,L,Predicted N6-adenine-specific DNA methylase,0,2,0,0,2
COG0117,H,Pyrimidine deaminase,0,1,12,1,14
COG0118,E,Glutamine amidotransferase,0,3,9,4,16
COG0119,E,Isopropylmalate/homocitrate/citramalate synthases,3,6,72,26,107
COG0120,G,Ribose 5-phosphate isomerase,0,4,0,8,12
COG0121,R,Predicted glutamine amidotransferase,0,1,15,1,17
COG0122,L,3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase,0,1,28,14,43
COG0123,BQ,"Deacetylases, including yeast histone deacetylase and acetoin utilization protein",0,5,13,9,27
COG0124,J,Histidyl-tRNA synthetase,0,4,27,8,39
COG0125,F,Thymidylate kinase,0,4,33,13,50
COG0126,G,3-phosphoglycerate kinase,0,2,17,14,33
COG0127,F,Xanthosine triphosphate pyrophosphatase,0,4,16,6,26
COG0128,E,5-enolpyruvylshikimate-3-phosphate synthase,0,2,15,9,26
COG0129,EG,Dihydroxyacid dehydratase/phosphogluconate dehydratase,2,7,66,15,90
COG0130,J,Pseudouridine synthase,6,2,16,6,30
COG0131,E,Imidazoleglycerol-phosphate dehydratase,0,2,15,1,18
COG0132,H,Dethiobiotin synthetase,0,1,0,1,2
COG0133,E,Tryptophan synthase beta chain,2,3,31,5,41
COG0134,E,Indole-3-glycerol phosphate synthase,1,5,13,5,24
COG0135,E,Phosphoribosylanthranilate isomerase,0,3,18,2,23
COG0136,E,Aspartate-semialdehyde dehydrogenase,0,3,16,13,32
COG0137,E,Argininosuccinate synthase,1,4,37,14,56
COG0138,F,AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful),2,4,18,6,30
COG0139,E,Phosphoribosyl-AMP cyclohydrolase,1,1,15,4,21
COG0140,E,Phosphoribosyl-ATP pyrophosphohydrolase,0,1,16,1,18
COG0141,E,Histidinol dehydrogenase,2,3,24,5,34
COG0142,H,Geranylgeranyl pyrophosphate synthase,0,4,50,31,85
COG0143,J,Methionyl-tRNA synthetase,2,7,18,18,45
COG0144,J,tRNA and rRNA cytosine-C5-methylases,0,4,18,2,24
COG0145,EQ,"N-methylhydantoinase A/acetone carboxylase, beta subunit",2,4,3,5,14
COG0146,EQ,"N-methylhydantoinase B/acetone carboxylase, alpha subunit",1,1,0,11,13
COG0147,EH,Anthranilate/para-aminobenzoate synthases component I,3,5,43,16,67
COG0148,G,Enolase,8,5,14,9,36
COG0149,G,Triosephosphate isomerase,0,3,17,5,25
COG0150,F,Phosphoribosylaminoimidazole (AIR) synthetase,0,14,20,7,41
COG0151,F,Phosphoribosylamine-glycine ligase,0,4,19,8,31
COG0152,F,Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase,0,4,27,12,43
COG0153,G,Galactokinase,0,2,13,5,20
COG0154,J,Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases,6,19,71,30,126
COG0155,P,"Sulfite reductase, beta subunit (hemoprotein)",1,6,32,14,53
COG0156,H,7-keto-8-aminopelargonate synthetase and related enzymes,6,5,16,20,47
COG0157,H,Nicotinate-nucleotide pyrophosphorylase,1,7,17,7,32
COG0158,G,"Fructose-1,6-bisphosphatase",0,2,0,0,2
COG0159,E,Tryptophan synthase alpha chain,0,3,11,6,20
COG0160,E,4-aminobutyrate aminotransferase and related aminotransferases,0,10,31,23,64
COG0161,H,Adenosylmethionine-8-amino-7-oxononanoate aminotransferase,8,10,25,13,56
COG0162,J,Tyrosyl-tRNA synthetase,0,3,9,17,29
COG0163,H,3-polyprenyl-4-hydroxybenzoate decarboxylase,2,2,2,9,15
COG0164,L,Ribonuclease HII,0,3,20,2,25
COG0165,E,Argininosuccinate lyase,2,8,5,13,28
COG0166,G,Glucose-6-phosphate isomerase,0,8,7,7,22
COG0167,F,Dihydroorotate dehydrogenase,1,5,21,13,40
COG0168,P,"Trk-type K+ transport systems, membrane components",0,3,47,0,50
COG0169,E,Shikimate 5-dehydrogenase,0,7,46,8,61
COG0170,I,Dolichol kinase,0,0,0,0,0
COG0171,H,NAD synthase,0,3,14,6,23
COG0172,J,Seryl-tRNA synthetase,2,5,13,14,34
COG0173,J,Aspartyl-tRNA synthetase,0,4,28,11,43
COG0174,E,Glutamine synthetase,1,15,42,22,80
COG0175,EH,3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes,0,4,30,8,42
COG0176,G,Transaldolase,2,3,8,9,22
COG0177,L,Predicted EndoIII-related endonuclease,0,2,9,13,24
COG0178,L,Excinuclease ATPase subunit,10,17,67,43,137
COG0179,Q,"2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)",0,8,133,15,156
COG0180,J,Tryptophanyl-tRNA synthetase,0,2,18,11,31
COG0181,H,Porphobilinogen deaminase,2,2,38,12,54
COG0182,J,"Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family",2,1,1,10,14
COG0183,I,Acetyl-CoA acetyltransferase,2,26,168,33,229
COG0184,J,Ribosomal protein S15P/S13E,3,1,14,2,20
COG0185,J,Ribosomal protein S19,0,2,16,2,20
COG0186,J,Ribosomal protein S17,6,4,18,3,31
COG0187,L,"Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit",9,12,40,13,74
COG0188,L,"Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit",4,11,42,20,77
COG0189,HJ,Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase),1,3,3,7,14
COG0190,H,"5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase",0,2,29,16,47
COG0191,G,Fructose/tagatose bisphosphate aldolase,0,2,15,2,19
COG0192,H,S-adenosylmethionine synthetase,0,14,21,11,46
COG0193,J,Peptidyl-tRNA hydrolase,0,1,15,2,18
COG0194,F,Guanylate kinase,1,2,12,2,17
COG0195,K,Transcription elongation factor,2,4,17,4,27
COG0196,H,FAD synthase,3,5,14,6,28
COG0197,J,Ribosomal protein L16/L10E,2,3,18,3,26
COG0198,J,Ribosomal protein L24,2,6,12,11,31
COG0199,J,Ribosomal protein S14,1,2,9,1,13
COG0200,J,Ribosomal protein L15,2,2,16,3,23
COG0201,U,Preprotein translocase subunit SecY,2,5,12,16,35
COG0202,K,"DNA-directed RNA polymerase, alpha subunit/40 kD subunit",2,5,10,10,27
COG0203,J,Ribosomal protein L17,0,1,10,3,14
COG0204,I,1-acyl-sn-glycerol-3-phosphate acyltransferase,1,9,52,12,74
COG0205,G,6-phosphofructokinase,2,7,14,10,33
COG0206,D,Cell division GTPase,0,3,20,7,30
COG0207,F,Thymidylate synthase,0,2,13,1,16
COG0208,F,"Ribonucleotide reductase, beta subunit",1,11,19,0,31
COG0209,F,"Ribonucleotide reductase, alpha subunit",1,18,27,21,67
COG0210,L,Superfamily I DNA and RNA helicases,3,19,117,22,161
COG0211,J,Ribosomal protein L27,0,1,11,1,13
COG0212,H,5-formyltetrahydrofolate cyclo-ligase,0,1,10,3,14
COG0213,F,Thymidine phosphorylase,0,0,12,2,14
COG0214,H,Pyridoxine biosynthesis enzyme,0,0,33,5,38
COG0215,J,Cysteinyl-tRNA synthetase,5,3,36,16,60
COG0216,J,Protein chain release factor A,0,10,16,8,34
COG0217,S,Uncharacterized conserved protein,4,3,31,7,45
COG0218,R,Predicted GTPase,0,7,0,0,7
COG0219,J,Predicted rRNA methylase (SpoU class),0,2,12,3,17
COG0220,R,Predicted S-adenosylmethionine-dependent methyltransferase,0,1,20,0,21
COG0221,C,Inorganic pyrophosphatase,1,1,16,6,24
COG0222,J,Ribosomal protein L7/L12,0,1,14,0,15
COG0223,J,Methionyl-tRNA formyltransferase,1,7,31,6,45
COG0224,C,"F0F1-type ATP synthase, gamma subunit",1,1,20,4,26
COG0225,O,Peptide methionine sulfoxide reductase,0,3,21,11,35
COG0226,P,"ABC-type phosphate transport system, periplasmic component",0,6,31,10,47
COG0227,J,Ribosomal protein L28,0,1,15,4,20
COG0228,J,Ribosomal protein S16,0,1,14,2,17
COG0229,O,Conserved domain frequently associated with peptide methionine sulfoxide reductase,0,2,15,8,25
COG0230,J,Ribosomal protein L34,0,0,0,0,0
COG0231,J,Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A),0,1,13,10,24
COG0232,F,dGTP triphosphohydrolase,0,1,30,8,39
COG0233,J,Ribosome recycling factor,2,3,16,5,26
COG0234,O,Co-chaperonin GroES (HSP10),5,3,14,3,25
COG0235,G,Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases,0,7,14,18,39
COG0236,IQ,Acyl carrier protein,2,6,13,6,27
COG0237,H,Dephospho-CoA kinase,0,5,18,3,26
COG0238,J,Ribosomal protein S18,1,3,13,7,24
COG0239,D,Integral membrane protein possibly involved in chromosome condensation,0,1,16,0,17
COG0240,C,Glycerol-3-phosphate dehydrogenase,0,7,19,3,29
COG0241,E,Histidinol phosphatase and related phosphatases,0,2,0,5,7
COG0242,J,N-formylmethionyl-tRNA deformylase,0,3,45,5,53
COG0243,C,"Anaerobic dehydrogenases, typically selenocysteine-containing",6,16,31,17,70
COG0244,J,Ribosomal protein L10,0,1,18,4,23
COG0245,I,"2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase",0,1,12,1,14
COG0246,G,Mannitol-1-phosphate/altronate dehydrogenases,0,1,17,0,18
COG0247,C,Fe-S oxidoreductase,1,7,21,4,33
COG0248,FP,Exopolyphosphatase,0,2,31,14,47
COG0249,L,Mismatch repair ATPase (MutS family),1,14,0,14,29
COG0250,K,Transcription antiterminator,1,5,17,10,33
COG0251,J,"Putative translation initiation inhibitor, yjgF family",0,9,26,20,55
COG0252,EJ,L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D,0,3,0,7,10
COG0253,E,Diaminopimelate epimerase,0,5,16,4,25
COG0254,J,Ribosomal protein L31,0,1,16,7,24
COG0255,J,Ribosomal protein L29,1,3,16,1,21
COG0256,J,Ribosomal protein L18,0,2,16,6,24
COG0257,J,Ribosomal protein L36,0,1,0,0,1
COG0258,L,5'-3' exonuclease (including N-terminal domain of PolI),3,3,5,7,18
COG0259,H,Pyridoxamine-phosphate oxidase,0,1,0,2,3
COG0260,E,Leucyl aminopeptidase,0,2,11,8,21
COG0261,J,Ribosomal protein L21,0,3,13,3,19
COG0262,H,Dihydrofolate reductase,1,4,76,22,103
COG0263,E,Glutamate 5-kinase,0,3,30,0,33
COG0264,J,Translation elongation factor Ts,1,3,16,7,27
COG0265,O,"Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain",7,12,33,45,97
COG0266,L,Formamidopyrimidine-DNA glycosylase,0,9,45,7,61
COG0267,J,Ribosomal protein L33,0,1,2,0,3
COG0268,J,Ribosomal protein S20,0,1,7,0,8
COG0269,G,3-hexulose-6-phosphate synthase and related proteins,0,0,0,0,0
COG0270,L,Site-specific DNA methylase,0,6,27,3,36
COG0271,T,Stress-induced morphogen (activity unknown),0,1,0,0,1
COG0272,L,NAD-dependent DNA ligase (contains BRCT domain type II),4,7,20,12,43
COG0274,F,Deoxyribose-phosphate aldolase,0,1,16,5,22
COG0275,M,Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis,0,2,20,5,27
COG0276,H,Protoheme ferro-lyase (ferrochelatase),1,1,26,10,38
COG0277,C,FAD/FMN-containing dehydrogenases,2,13,81,15,111
COG0278,O,Glutaredoxin-related protein,0,1,0,0,1
COG0279,G,Phosphoheptose isomerase,10,2,0,4,16
COG0280,C,Phosphotransacetylase,6,2,0,4,12
COG0281,C,Malic enzyme,1,9,23,6,39
COG0282,C,Acetate kinase,0,2,0,6,8
COG0283,F,Cytidylate kinase,0,4,17,7,28
COG0284,F,Orotidine-5'-phosphate decarboxylase,1,3,12,5,21
COG0285,H,Folylpolyglutamate synthase,0,4,15,3,22
COG0286,V,Type I restriction-modification system methyltransferase subunit,0,2,0,1,3
COG0287,E,Prephenate dehydrogenase,0,1,16,7,24
COG0288,P,Carbonic anhydrase,0,6,16,5,27
COG0289,E,Dihydrodipicolinate reductase,0,1,16,1,18
COG0290,J,Translation initiation factor 3 (IF-3),0,5,13,5,23
COG0291,J,Ribosomal protein L35,1,1,14,2,18
COG0292,J,Ribosomal protein L20,1,2,14,2,19
COG0293,J,23S rRNA methylase,0,1,0,1,2
COG0294,H,Dihydropteroate synthase and related enzymes,0,3,39,13,55
COG0295,F,Cytidine deaminase,0,0,25,0,25
COG0296,G,"1,4-alpha-glucan branching enzyme",3,3,0,23,29
COG0297,G,Glycogen synthase,1,4,0,4,9
COG0298,O,Hydrogenase maturation factor,0,0,0,1,1
COG0299,F,Folate-dependent phosphoribosylglycinamide formyltransferase PurN,0,3,15,6,24
COG0300,R,Short-chain dehydrogenases of various substrate specificities,0,22,36,50,108
COG0301,H,Thiamine biosynthesis ATP pyrophosphatase,4,4,0,1,9
COG0302,H,GTP cyclohydrolase I,0,2,16,3,21
COG0303,H,Molybdopterin biosynthesis enzyme,2,7,36,18,63
COG0304,IQ,3-oxoacyl-(acyl-carrier-protein) synthase,3,21,15,38,77
COG0305,L,Replicative DNA helicase,1,11,17,17,46
COG0306,P,Phosphate/sulphate permeases,0,7,32,8,47
COG0307,H,Riboflavin synthase alpha chain,0,3,15,3,21
COG0308,E,Aminopeptidase N,5,7,50,16,78
COG0309,O,Hydrogenase maturation factor,0,1,0,3,4
COG0310,P,"ABC-type Co2+ transport system, permease component",0,0,0,0,0
COG0311,H,Predicted glutamine amidotransferase involved in pyridoxine biosynthesis,0,0,17,2,19
COG0312,R,Predicted Zn-dependent proteases and their inactivated homologs,2,9,0,16,27
COG0313,R,Predicted methyltransferases,5,1,11,1,18
COG0314,H,"Molybdopterin converting factor, large subunit",0,1,13,5,19
COG0315,H,Molybdenum cofactor biosynthesis enzyme,2,1,27,3,33
COG0316,S,Uncharacterized conserved protein,4,5,14,7,30
COG0317,TK,Guanosine polyphosphate pyrophosphohydrolases/synthetases,6,15,42,11,74
COG0318,IQ,Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II,3,83,223,72,381
COG0319,R,Predicted metal-dependent hydrolase,0,3,14,3,20
COG0320,H,Lipoate synthase,0,6,26,3,35
COG0321,H,Lipoate-protein ligase B,0,1,13,6,20
COG0322,L,Nuclease subunit of the excinuclease complex,3,6,20,8,37
COG0323,L,DNA mismatch repair enzyme (predicted ATPase),1,6,0,16,23
COG0324,J,tRNA delta(2)-isopentenylpyrophosphate transferase,1,2,18,8,29
COG0325,R,Predicted enzyme with a TIM-barrel fold,0,10,33,0,43
COG0326,O,"Molecular chaperone, HSP90 family",1,4,0,0,5
COG0327,S,Uncharacterized conserved protein,0,1,8,4,13
COG0328,L,Ribonuclease HI,1,2,9,2,14
COG0329,EM,Dihydrodipicolinate synthase/N-acetylneuraminate lyase,0,16,101,14,131
COG0330,O,"Membrane protease subunits, stomatin/prohibitin homologs",0,8,17,13,38
COG0331,I,(acyl-carrier-protein) S-malonyltransferase,0,5,14,7,26
COG0332,I,3-oxoacyl-[acyl-carrier-protein] synthase III,2,7,58,11,78
COG0333,J,Ribosomal protein L32,0,1,0,0,1
COG0334,E,Glutamate dehydrogenase/leucine dehydrogenase,1,3,14,16,34
COG0335,J,Ribosomal protein L19,0,3,12,0,15
COG0336,J,tRNA-(guanine-N1)-methyltransferase,4,3,19,4,30
COG0337,E,3-dehydroquinate synthetase,0,6,22,2,30
COG0338,L,Site-specific DNA methylase,0,1,0,4,5
COG0339,E,Zn-dependent oligopeptidases,2,14,22,18,56
COG0340,H,Biotin-(acetyl-CoA carboxylase) ligase,0,1,16,6,23
COG0341,U,Preprotein translocase subunit SecF,3,2,16,5,26
COG0342,U,Preprotein translocase subunit SecD,0,6,17,16,39
COG0343,J,Queuine/archaeosine tRNA-ribosyltransferase,0,4,14,13,31
COG0344,S,Predicted membrane protein,3,3,0,2,8
COG0345,E,Pyrroline-5-carboxylate reductase,1,6,14,12,33
COG0346,E,Lactoylglutathione lyase and related lyases,0,1,15,6,22
COG0347,E,Nitrogen regulatory protein PII,0,1,0,6,7
COG0348,C,Polyferredoxin,0,5,0,0,5
COG0349,J,Ribonuclease D,0,3,13,1,17
COG0350,L,Methylated DNA-protein cysteine methyltransferase,1,4,16,5,26
COG0351,H,Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase,0,4,26,5,35
COG0352,H,Thiamine monophosphate synthase,1,1,13,3,18
COG0353,L,Recombinational DNA repair protein (RecF pathway),1,4,14,9,28
COG0354,R,Predicted aminomethyltransferase related to GcvT,0,2,11,2,15
COG0355,C,"F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)",0,2,12,1,15
COG0356,C,"F0F1-type ATP synthase, subunit a",0,6,12,5,23
COG0357,M,Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division,0,2,14,0,16
COG0358,L,DNA primase (bacterial type),0,4,15,14,33
COG0359,J,Ribosomal protein L9,0,2,13,3,18
COG0360,J,Ribosomal protein S6,2,2,14,1,19
COG0361,J,Translation initiation factor 1 (IF-1),1,7,8,6,22
COG0362,G,6-phosphogluconate dehydrogenase,0,0,18,11,29
COG0363,G,6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase,0,2,33,8,43
COG0364,G,Glucose-6-phosphate 1-dehydrogenase,2,6,40,17,65
COG0365,I,Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases,6,13,148,38,205
COG0366,G,Glycosidases,4,10,18,5,37
COG0367,E,Asparagine synthase (glutamine-hydrolyzing),6,14,7,21,48
COG0368,H,Cobalamin-5-phosphate synthase,0,0,0,7,7
COG0369,P,"Sulfite reductase, alpha subunit (flavoprotein)",0,10,0,1,11
COG0370,P,Fe2+ transport system protein B,1,1,0,1,3
COG0371,C,Glycerol dehydrogenase and related enzymes,0,0,2,4,6
COG0372,C,Citrate synthase,1,3,38,10,52
COG0373,H,Glutamyl-tRNA reductase,1,2,15,11,29
COG0374,C,"Ni,Fe-hydrogenase I large subunit",0,0,0,0,0
COG0375,R,Zn finger protein HypA/HybF (possibly regulating hydrogenase expression),0,0,0,1,1
COG0376,P,Catalase (peroxidase I),3,4,19,3,29
COG0377,C,NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases,11,2,3,14,30
COG0378,OK,Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase,0,2,16,16,34
COG0379,H,Quinolinate synthase,0,3,19,4,26
COG0380,G,Trehalose-6-phosphate synthase,0,1,16,2,19
COG0381,M,UDP-N-acetylglucosamine 2-epimerase,0,3,16,10,29
COG0382,H,4-hydroxybenzoate polyprenyltransferase and related prenyltransferases,1,2,15,3,21
COG0383,G,Alpha-mannosidase,0,0,16,6,22
COG0384,R,"Predicted epimerase, PhzC/PhzF homolog",0,3,27,6,36
COG0385,R,Predicted Na+-dependent transporter,0,3,16,1,20
COG0386,O,Glutathione peroxidase,0,2,15,2,19
COG0387,P,Ca2+/H+ antiporter,0,0,0,7,7
COG0388,R,Predicted amidohydrolase,0,15,21,12,48
COG0389,L,Nucleotidyltransferase/DNA polymerase involved in DNA repair,0,1,43,11,55
COG0390,R,"ABC-type uncharacterized transport system, permease component",2,0,0,0,2
COG0391,S,Uncharacterized conserved protein,0,2,24,3,29
COG0392,S,Predicted integral membrane protein,0,2,0,1,3
COG0393,S,Uncharacterized conserved protein,0,2,0,0,2
COG0394,T,Protein-tyrosine-phosphatase,0,2,43,5,50
COG0395,G,"ABC-type sugar transport system, permease component",1,5,32,12,50
COG0396,O,"ABC-type transport system involved in Fe-S cluster assembly, ATPase component",1,1,10,5,17
COG0397,S,Uncharacterized conserved protein,0,3,0,1,4
COG0398,S,Uncharacterized conserved protein,0,0,14,3,17
COG0399,M,Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis,1,17,46,30,94
COG0400,R,Predicted esterase,0,4,32,5,41
COG0401,S,Uncharacterized homolog of Blt101,0,0,0,0,0
COG0402,FR,Cytosine deaminase and related metal-dependent hydrolases,1,16,0,12,29
COG0403,E,"Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain",6,6,1,8,21
COG0404,E,Glycine cleavage system T protein (aminomethyltransferase),2,10,33,16,61
COG0405,E,Gamma-glutamyltransferase,2,11,14,22,49
COG0406,G,"Fructose-2,6-bisphosphatase",0,6,87,15,108
COG0407,H,Uroporphyrinogen-III decarboxylase,0,5,18,1,24
COG0408,H,Coproporphyrinogen III oxidase,0,3,0,0,3
COG0409,O,Hydrogenase maturation factor,0,2,0,0,2
COG0410,E,"ABC-type branched-chain amino acid transport systems, ATPase component",0,11,16,3,30
COG0411,E,"ABC-type branched-chain amino acid transport systems, ATPase component",4,6,16,12,38
COG0412,Q,Dienelactone hydrolase and related enzymes,0,4,29,26,59
COG0413,H,Ketopantoate hydroxymethyltransferase,0,6,19,4,29
COG0414,H,Panthothenate synthetase,0,6,15,5,26
COG0415,L,Deoxyribodipyrimidine photolyase,0,2,25,8,35
COG0416,I,Fatty acid/phospholipid biosynthesis enzyme,0,6,2,7,15
COG0417,L,DNA polymerase elongation subunit (family B),5,8,1,11,25
COG0418,F,Dihydroorotase,4,1,0,0,5
COG0419,L,ATPase involved in DNA repair,0,3,26,3,32
COG0420,L,DNA repair exonuclease,1,2,24,3,30
COG0421,E,Spermidine synthase,1,4,28,5,38
COG0422,H,Thiamine biosynthesis protein ThiC,0,5,15,1,21
COG0423,J,Glycyl-tRNA synthetase (class II),6,2,16,19,43
COG0424,D,Nucleotide-binding protein implicated in inhibition of septum formation,0,4,15,2,21
COG0425,O,"Predicted redox protein, regulator of disulfide bond formation",0,2,0,1,3
COG0426,C,Uncharacterized flavoproteins,0,1,0,1,2
COG0427,C,Acetyl-CoA hydrolase,0,4,23,4,31
COG0428,P,Predicted divalent heavy-metal cations transporter,0,0,11,2,13
COG0429,R,Predicted hydrolase of the alpha/beta-hydrolase fold,0,1,0,0,1
COG0430,A,RNA 3'-terminal phosphate cyclase,0,0,0,0,0
COG0431,R,Predicted flavoprotein,0,4,46,5,55
COG0432,S,Uncharacterized conserved protein,0,4,1,7,12
COG0433,R,Predicted ATPase,1,3,22,3,29
COG0434,R,Predicted TIM-barrel enzyme,0,2,0,2,4
COG0435,O,Predicted glutathione S-transferase,0,1,9,5,15
COG0436,E,Aspartate/tyrosine/aromatic aminotransferase,5,14,102,29,150
COG0437,C,Fe-S-cluster-containing hydrogenase components 1,4,7,1,8,20
COG0438,M,Glycosyltransferase,9,18,101,61,189
COG0439,I,Biotin carboxylase,2,1,21,5,29
COG0440,E,"Acetolactate synthase, small (regulatory) subunit",1,1,15,3,20
COG0441,J,Threonyl-tRNA synthetase,2,7,39,8,56
COG0442,J,Prolyl-tRNA synthetase,1,6,18,12,37
COG0443,O,Molecular chaperone,1,17,25,40,83
COG0444,EP,"ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",0,6,72,17,95
COG0445,D,NAD/FAD-utilizing enzyme apparently involved in cell division,1,4,0,5,10
COG0446,R,Uncharacterized NAD(FAD)-dependent dehydrogenases,0,3,12,1,16
COG0447,H,Dihydroxynaphthoic acid synthase,0,0,20,1,21
COG0448,G,ADP-glucose pyrophosphorylase,2,2,1,9,14
COG0449,M,"Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains",2,6,24,19,51
COG0450,O,Peroxiredoxin,3,8,3,8,22
COG0451,MG,Nucleoside-diphosphate-sugar epimerases,2,31,63,36,132
COG0452,H,Phosphopantothenoylcysteine synthetase/decarboxylase,0,9,14,11,34
COG0454,KR,Histone acetyltransferase HPA2 and related acetyltransferases,0,0,0,0,0
COG0455,D,ATPases involved in chromosome partitioning,0,2,22,4,28
COG0456,R,Acetyltransferases,1,5,83,6,95
COG0457,R,FOG: TPR repeat,0,1,0,1,2
COG0458,EF,Carbamoylphosphate synthase large subunit (split gene in MJ),0,6,51,27,84
COG0459,O,Chaperonin GroEL (HSP60 family),5,12,41,26,84
COG0460,E,Homoserine dehydrogenase,0,6,15,5,26
COG0461,F,Orotate phosphoribosyltransferase,0,2,14,6,22
COG0462,FE,Phosphoribosylpyrophosphate synthetase,6,9,20,11,46
COG0463,M,Glycosyltransferases involved in cell wall biogenesis,5,13,52,35,105
COG0464,O,ATPases of the AAA+ class,0,5,5,7,17
COG0465,O,ATP-dependent Zn proteases,2,13,31,18,64
COG0466,O,"ATP-dependent Lon protease, bacterial type",5,23,1,19,48
COG0467,T,RecA-superfamily ATPases implicated in signal transduction,2,4,1,9,16
COG0468,L,RecA/RadA recombinase,0,3,18,10,31
COG0469,G,Pyruvate kinase,0,13,30,10,53
COG0470,L,ATPase involved in DNA replication,0,0,0,0,0
COG0471,P,Di- and tricarboxylate transporters,1,0,0,2,3
COG0472,M,UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase,1,5,30,6,42
COG0473,CE,Isocitrate/isopropylmalate dehydrogenase,2,8,39,17,66
COG0474,P,Cation transport ATPase,10,20,0,19,49
COG0475,P,"Kef-type K+ transport systems, membrane components",0,5,0,5,10
COG0476,H,Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2,0,2,29,26,57
COG0477,GEPR,Permeases of the major facilitator superfamily,0,0,0,0,0
COG0478,T,RIO-like serine/threonine protein kinase fused to N-terminal HTH domain,0,0,0,2,2
COG0479,C,"Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit",4,2,15,11,32
COG0480,J,Translation elongation factors (GTPases),4,7,36,20,67
COG0481,M,Membrane GTPase LepA,4,5,27,12,48
COG0482,J,"Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain",1,2,12,6,21
COG0483,G,"Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family",1,4,43,15,63
COG0484,O,DnaJ-class molecular chaperone with C-terminal Zn finger domain,2,9,63,33,107
COG0486,R,Predicted GTPase,3,7,1,10,21
COG0488,R,ATPase components of ABC transporters with duplicated ATPase domains,9,13,137,23,182
COG0489,D,ATPases involved in chromosome partitioning,2,4,13,11,30
COG0490,P,"Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels",0,4,0,0,4
COG0491,R,"Zn-dependent hydrolases, including glyoxylases",2,2,89,27,120
COG0492,O,Thioredoxin reductase,0,11,38,33,82
COG0493,ER,NADPH-dependent glutamate synthase beta chain and related oxidoreductases,0,5,39,8,52
COG0494,LR,NTP pyrophosphohydrolases including oxidative damage repair enzymes,1,0,23,5,29
COG0495,J,Leucyl-tRNA synthetase,7,12,26,19,64
COG0496,R,Predicted acid phosphatase,1,2,0,1,4
COG0497,L,ATPase involved in DNA repair,1,3,21,5,30
COG0498,E,Threonine synthase,0,4,24,19,47
COG0499,H,S-adenosylhomocysteine hydrolase,6,6,3,14,29
COG0500,QR,SAM-dependent methyltransferases,0,0,0,0,0
COG0501,O,Zn-dependent protease with chaperone function,0,5,31,8,44
COG0502,H,Biotin synthase and related enzymes,0,1,11,4,16
COG0503,F,Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins,0,2,4,4,10
COG0504,F,CTP synthase (UTP-ammonia lyase),1,14,18,16,49
COG0505,EF,Carbamoylphosphate synthase small subunit,0,5,24,17,46
COG0506,E,Proline dehydrogenase,0,3,5,5,13
COG0507,L,"ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member",3,9,8,2,22
COG0508,C,"Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes",7,12,87,24,130
COG0509,E,Glycine cleavage system H protein (lipoate-binding),0,3,8,4,15
COG0510,M,Predicted choline kinase involved in LPS biosynthesis,0,0,0,2,2
COG0511,I,Biotin carboxyl carrier protein,0,1,8,2,11
COG0512,EH,Anthranilate/para-aminobenzoate synthases component II,0,3,16,3,22
COG0513,LKJ,Superfamily II DNA and RNA helicases,8,11,58,11,88
COG0514,L,Superfamily II DNA helicase,1,6,21,12,40
COG0515,RTKL,Serine/threonine protein kinase,21,44,58,79,202
COG0516,F,IMP dehydrogenase/GMP reductase,0,5,33,8,46
COG0517,R,FOG: CBS domain,0,2,2,8,12
COG0518,F,GMP synthase - Glutamine amidotransferase domain,3,3,19,11,36
COG0519,F,"GMP synthase, PP-ATPase domain/subunit",1,2,32,7,42
COG0520,E,Selenocysteine lyase,1,19,21,39,80
COG0521,H,Molybdopterin biosynthesis enzymes,0,1,15,7,23
COG0522,J,Ribosomal protein S4 and related proteins,3,2,15,7,27
COG0523,R,Putative GTPases (G3E family),0,8,28,11,47
COG0524,G,"Sugar kinases, ribokinase family",0,9,65,8,82
COG0525,J,Valyl-tRNA synthetase,7,10,32,25,74
COG0526,OC,Thiol-disulfide isomerase and thioredoxins,1,5,31,7,44
COG0527,E,Aspartokinases,2,16,17,15,50
COG0528,F,Uridylate kinase,0,4,25,8,37
COG0529,P,Adenylylsulfate kinase and related kinases,0,11,1,7,19
COG0530,P,Ca2+/Na+ antiporter,0,3,1,2,6
COG0531,E,Amino acid transporters,2,14,74,19,109
COG0532,J,Translation initiation factor 2 (IF-2; GTPase),1,6,12,11,30
COG0533,O,Metal-dependent proteases with possible chaperone activity,1,5,32,7,45
COG0534,V,Na+-driven multidrug efflux pump,0,9,11,8,28
COG0535,R,Predicted Fe-S oxidoreductases,0,10,0,10,20
COG0536,R,Predicted GTPase,0,3,28,7,38
COG0537,FGR,Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases,2,5,46,15,68
COG0538,C,Isocitrate dehydrogenases,4,2,0,5,11
COG0539,J,Ribosomal protein S1,9,6,33,14,62
COG0540,F,"Aspartate carbamoyltransferase, catalytic chain",0,1,13,7,21
COG0541,U,Signal recognition particle GTPase,2,3,26,13,44
COG0542,O,"ATPases with chaperone activity, ATP-binding subunit",7,26,81,35,149
COG0543,HC,2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases,0,4,16,5,25
COG0544,O,FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor),0,2,17,8,27
COG0545,O,FKBP-type peptidyl-prolyl cis-trans isomerases 1,0,4,31,3,38
COG0546,R,Predicted phosphatases,0,3,16,3,22
COG0547,E,Anthranilate phosphoribosyltransferase,0,6,22,14,42
COG0548,E,Acetylglutamate kinase,0,9,9,5,23
COG0549,E,Carbamate kinase,0,2,0,0,2
COG0550,L,Topoisomerase IA,2,11,16,15,44
COG0551,L,Zn-finger domain associated with topoisomerase type I,0,1,0,1,2
COG0552,U,Signal recognition particle GTPase,0,4,18,8,30
COG0553,KL,"Superfamily II DNA/RNA helicases, SNF2 family",0,5,45,3,53
COG0554,C,Glycerol kinase,2,3,24,7,36
COG0555,O,"ABC-type sulfate transport system, permease component",0,1,0,3,4
COG0556,L,Helicase subunit of the DNA excision repair complex,0,4,25,17,46
COG0557,K,Exoribonuclease R,3,3,14,6,26
COG0558,I,Phosphatidylglycerophosphate synthase,0,3,45,13,61
COG0559,E,"Branched-chain amino acid ABC-type transport system, permease components",0,7,17,3,27
COG0560,E,Phosphoserine phosphatase,0,4,27,2,33
COG0561,R,Predicted hydrolases of the HAD superfamily,0,8,41,5,54
COG0562,M,UDP-galactopyranose mutase,0,0,0,0,0
COG0563,F,Adenylate kinase and related kinases,0,3,13,5,21
COG0564,J,"Pseudouridylate synthases, 23S RNA-specific",0,8,42,14,64
COG0565,J,rRNA methylase,0,1,0,2,3
COG0566,J,rRNA methylases,0,2,79,9,90
COG0567,C,"2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes",2,10,28,25,65
COG0568,K,"DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)",4,11,14,12,41
COG0569,P,"K+ transport systems, NAD-binding component",0,2,57,4,63
COG0571,K,dsRNA-specific ribonuclease,0,2,17,6,25
COG0572,F,Uridine kinase,0,1,21,2,24
COG0573,P,"ABC-type phosphate transport system, permease component",0,11,17,7,35
COG0574,G,Phosphoenolpyruvate synthase/pyruvate phosphate dikinase,3,8,41,17,69
COG0575,I,CDP-diglyceride synthetase,0,0,16,2,18
COG0576,O,Molecular chaperone GrpE (heat shock protein),0,7,16,7,30
COG0577,V,"ABC-type antimicrobial peptide transport system, permease component",1,15,19,15,50
COG0578,C,Glycerol-3-phosphate dehydrogenase,0,8,24,3,35
COG0579,R,Predicted dehydrogenase,1,6,28,5,40
COG0580,G,Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family),4,1,36,8,49
COG0581,P,"ABC-type phosphate transport system, permease component",2,2,16,6,26
COG0582,L,Integrase,0,1,0,0,1
COG0583,K,Transcriptional regulator,1,113,320,28,462
COG0584,C,Glycerophosphoryl diester phosphodiesterase,0,4,44,4,52
COG0585,S,Uncharacterized conserved protein,0,2,0,3,5
COG0586,S,Uncharacterized membrane-associated protein,0,1,42,7,50
COG0587,L,"DNA polymerase III, alpha subunit",2,14,51,56,123
COG0588,G,Phosphoglycerate mutase 1,0,0,17,0,17
COG0589,T,Universal stress protein UspA and related nucleotide-binding proteins,1,11,43,18,73
COG0590,FJ,Cytosine/adenosine deaminases,0,0,30,2,32
COG0591,ER,Na+/proline symporter,0,8,60,12,80
COG0592,L,DNA polymerase sliding clamp subunit (PCNA homolog),2,2,16,7,27
COG0593,L,ATPase involved in DNA replication initiation,1,4,15,10,30
COG0594,J,RNase P protein component,0,2,13,3,18
COG0595,R,Predicted hydrolase of the metallo-beta-lactamase superfamily,0,4,17,7,28
COG0596,R,Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily),2,27,181,52,262
COG0597,MU,Lipoprotein signal peptidase,0,3,15,3,21
COG0598,P,Mg2+ and Co2+ transporters,6,5,5,18,34
COG0599,S,Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit,0,1,14,3,18
COG0600,P,"ABC-type nitrate/sulfonate/bicarbonate transport system, permease component",2,9,171,30,212
COG0601,EP,"ABC-type dipeptide/oligopeptide/nickel transport systems, permease components",0,8,210,30,248
COG0602,O,Organic radical activating enzymes,1,3,0,7,11
COG0603,R,Predicted PP-loop superfamily ATPase,0,2,1,2,5
COG0604,CR,NADPH:quinone reductase and related Zn-dependent oxidoreductases,4,27,77,61,169
COG0605,P,Superoxide dismutase,0,1,19,5,25
COG0606,O,Predicted ATPase with chaperone activity,0,5,26,7,38
COG0607,P,Rhodanese-related sulfurtransferase,3,10,12,10,35
COG0608,L,Single-stranded DNA-specific exonuclease,4,5,0,7,16
COG0609,P,"ABC-type Fe3+-siderophore transport system, permease component",0,3,55,5,63
COG0610,V,"Type I site-specific restriction-modification system, R (restriction) subunit and related helicases",0,2,0,0,2
COG0611,H,Thiamine monophosphate kinase,0,3,16,3,22
COG0612,R,Predicted Zn-dependent peptidases,4,15,20,43,82
COG0613,R,Predicted metal-dependent phosphoesterases (PHP family),0,3,17,4,24
COG0614,P,"ABC-type Fe3+-hydroxamate transport system, periplasmic component",1,1,52,2,56
COG0615,MI,Cytidylyltransferase,0,0,14,4,18
COG0616,OU,Periplasmic serine proteases (ClpP class),1,8,0,5,14
COG0617,J,tRNA nucleotidyltransferase/poly(A) polymerase,9,5,17,1,32
COG0618,R,Exopolyphosphatase-related proteins,0,1,0,5,6
COG0619,P,"ABC-type cobalt transport system, permease component CbiQ and related transporters",0,0,18,1,19
COG0620,E,Methionine synthase II (cobalamin-independent),2,1,19,12,34
COG0621,J,2-methylthioadenine synthetase,1,13,23,31,68
COG0622,R,Predicted phosphoesterase,1,1,0,5,7
COG0623,I,Enoyl-[acyl-carrier-protein] reductase (NADH),0,4,0,3,7
COG0624,E,Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases,1,22,62,26,111
COG0625,O,Glutathione S-transferase,3,14,0,5,22
COG0626,E,Cystathionine beta-lyases/cystathionine gamma-synthases,1,8,54,17,80
COG0627,R,Predicted esterase,0,1,0,3,4
COG0628,R,Predicted permease,0,5,43,18,66
COG0629,L,Single-stranded DNA-binding protein,1,11,35,6,53
COG0630,NU,"Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis",0,0,0,1,1
COG0631,T,Serine/threonine protein phosphatase,3,3,31,12,49
COG0632,L,"Holliday junction resolvasome, DNA-binding subunit",1,2,15,6,24
COG0633,C,Ferredoxin,0,3,28,1,32
COG0634,F,Hypoxanthine-guanine phosphoribosyltransferase,0,2,20,4,26
COG0635,H,Coproporphyrinogen III oxidase and related Fe-S oxidoreductases,0,11,17,5,33
COG0636,C,"F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K",0,0,0,0,0
COG0637,R,Predicted phosphatase/phosphohexomutase,2,4,45,5,56
COG0638,O,"20S proteasome, alpha and beta subunits",0,0,4,7,11
COG0639,T,Diadenosine tetraphosphatase and related serine/threonine protein phosphatases,0,0,0,0,0
COG0640,K,Predicted transcriptional regulators,0,2,95,4,101
COG0641,R,Arylsulfatase regulator (Fe-S oxidoreductase),0,1,0,1,2
COG0642,T,Signal transduction histidine kinase,13,74,78,55,220
COG0643,NT,Chemotaxis protein histidine kinase and related kinases,0,7,0,3,10
COG0644,C,Dehydrogenases (flavoproteins),3,9,13,28,53
COG0645,R,Predicted kinase,0,2,0,1,3
COG0646,E,"Methionine synthase I (cobalamin-dependent), methyltransferase domain",0,4,0,10,14
COG0647,G,Predicted sugar phosphatases of the HAD superfamily,0,0,51,5,56
COG0648,L,Endonuclease IV,0,3,1,9,13
COG0649,C,NADH:ubiquinone oxidoreductase 49 kD subunit 7,2,8,1,17,28
COG0650,C,Formate hydrogenlyase subunit 4,0,0,0,2,2
COG0651,CP,"Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit",0,0,15,1,16
COG0652,O,Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family,0,5,12,9,26
COG0653,U,"Preprotein translocase subunit SecA (ATPase, RNA helicase)",12,7,21,14,54
COG0654,HC,2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases,1,8,171,21,201
COG0655,R,Multimeric flavodoxin WrbA,0,3,14,1,18
COG0656,R,"Aldo/keto reductases, related to diketogulonate reductase",1,12,60,8,81
COG0657,I,Esterase/lipase,0,4,59,17,80
COG0658,R,Predicted membrane metal-binding protein,0,0,5,0,5
COG0659,P,Sulfate permease and related transporters (MFS superfamily),1,11,28,13,53
COG0661,R,Predicted unusual protein kinase,0,9,12,8,29
COG0662,G,Mannose-6-phosphate isomerase,0,4,9,9,22
COG0663,R,"Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily",3,2,15,4,24
COG0664,T,cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases,1,12,16,21,50
COG0665,E,Glycine/D-amino acid oxidases (deaminating),3,31,95,11,140
COG0666,R,FOG: Ankyrin repeat,0,5,16,4,25
COG0667,C,Predicted oxidoreductases (related to aryl-alcohol dehydrogenases),4,10,65,65,144
COG0668,M,Small-conductance mechanosensitive channel,1,4,9,2,16
COG0669,H,Phosphopantetheine adenylyltransferase,0,0,14,2,16
COG0670,R,"Integral membrane protein, interacts with FtsH",0,4,0,0,4
COG0671,I,Membrane-associated phospholipid phosphatase,0,1,0,1,2
COG0672,P,High-affinity Fe2+/Pb2+ permease,0,2,15,3,20
COG0673,R,Predicted dehydrogenases and related proteins,2,15,46,53,116
COG0674,C,"Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit",0,3,2,17,22
COG0675,L,Transposase and inactivated derivatives,0,0,0,1,1
COG0676,G,Uncharacterized enzymes related to aldose 1-epimerase,0,3,0,0,3
COG0677,M,UDP-N-acetyl-D-mannosaminuronate dehydrogenase,0,1,70,12,83
COG0678,O,Peroxiredoxin,0,0,0,0,0
COG0679,R,Predicted permeases,1,3,55,1,60
COG0680,C,"Ni,Fe-hydrogenase maturation factor",0,0,0,0,0
COG0681,U,Signal peptidase I,1,1,19,2,23
COG0682,M,Prolipoprotein diacylglyceryltransferase,0,2,10,5,17
COG0683,E,"ABC-type branched-chain amino acid transport systems, periplasmic component",4,6,20,14,44
COG0684,H,Demethylmenaquinone methyltransferase,1,5,14,4,24
COG0685,E,"5,10-methylenetetrahydrofolate reductase",0,1,29,4,34
COG0686,E,Alanine dehydrogenase,0,2,17,7,26
COG0687,E,Spermidine/putrescine-binding periplasmic protein,0,24,30,7,61
COG0688,I,Phosphatidylserine decarboxylase,0,1,0,2,3
COG0689,J,RNase PH,0,2,19,5,26
COG0690,U,Preprotein translocase subunit SecE,0,1,11,1,13
COG0691,O,tmRNA-binding protein,0,2,8,1,11
COG0692,L,Uracil DNA glycosylase,0,2,16,1,19
COG0693,R,Putative intracellular protease/amidase,0,3,15,1,19
COG0694,O,Thioredoxin-like proteins and domains,0,0,0,1,1
COG0695,O,Glutaredoxin and related proteins,0,3,32,3,38
COG0696,G,Phosphoglyceromutase,2,3,0,6,11
COG0697,GER,Permeases of the drug/metabolite transporter (DMT) superfamily,0,1,0,0,1
COG0698,G,Ribose 5-phosphate isomerase RpiB,0,2,13,9,24
COG0699,R,Predicted GTPases (dynamin-related),0,0,0,0,0
COG0700,S,Uncharacterized membrane protein,0,2,0,1,3
COG0701,R,Predicted permeases,0,0,0,1,1
COG0702,MG,Predicted nucleoside-diphosphate-sugar epimerases,1,1,47,6,55
COG0703,E,Shikimate kinase,1,2,27,3,33
COG0704,P,Phosphate uptake regulator,2,2,17,7,28
COG0705,R,Uncharacterized membrane protein (homolog of Drosophila rhomboid),1,2,12,4,19
COG0706,U,Preprotein translocase subunit YidC,0,4,14,5,23
COG0707,M,UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase,1,4,20,10,35
COG0708,L,Exonuclease III,1,7,38,11,57
COG0709,E,Selenophosphate synthase,1,3,0,7,11
COG0710,E,3-dehydroquinate dehydratase,0,1,0,4,5
COG0711,C,"F0F1-type ATP synthase, subunit b",0,2,10,1,13
COG0712,C,"F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)",0,2,12,6,20
COG0713,C,NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K),2,3,0,5,10
COG0714,R,MoxR-like ATPases,0,11,9,26,46
COG0715,P,"ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components",9,8,126,23,166
COG0716,C,Flavodoxins,0,1,0,0,1
COG0717,F,Deoxycytidine deaminase,0,2,14,6,22
COG0718,S,Uncharacterized protein conserved in bacteria,0,2,0,1,3
COG0719,O,"ABC-type transport system involved in Fe-S cluster assembly, permease component",9,2,25,15,51
COG0720,H,6-pyruvoyl-tetrahydropterin synthase,0,1,0,7,8
COG0721,J,Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit,0,3,15,1,19
COG0722,E,3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase,0,7,0,2,9
COG0723,C,Rieske Fe-S protein,0,2,41,5,48
COG0724,R,RNA-binding proteins (RRM domain),4,1,0,8,13
COG0725,P,"ABC-type molybdate transport system, periplasmic component",0,3,14,2,19
COG0726,G,Predicted xylanase/chitin deacetylase,4,8,47,11,70
COG0727,R,Predicted Fe-S-cluster oxidoreductase,0,0,0,0,0
COG0728,R,"Uncharacterized membrane protein, putative virulence factor",1,8,16,3,28
COG0729,M,Outer membrane protein,0,1,0,0,1
COG0730,R,Predicted permeases,0,2,28,2,32
COG0731,C,Fe-S oxidoreductases,0,0,1,1,2
COG0732,V,Restriction endonuclease S subunits,0,0,0,0,0
COG0733,R,Na+-dependent transporters of the SNF family,0,2,17,0,19
COG0735,P,Fe2+/Zn2+ uptake regulation proteins,0,2,27,4,33
COG0736,I,Phosphopantetheinyl transferase (holo-ACP synthase),0,1,11,0,12
COG0737,F,"5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases",0,3,15,7,25
COG0738,G,Fucose permease,0,0,20,4,24
COG0739,M,Membrane proteins related to metalloendopeptidases,5,10,69,7,91
COG0740,OU,Protease subunit of ATP-dependent Clp proteases,4,8,27,7,46
COG0741,M,Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains),0,4,16,13,33
COG0742,L,N6-adenine-specific methylase,0,1,15,1,17
COG0743,I,1-deoxy-D-xylulose 5-phosphate reductoisomerase,0,3,21,13,37
COG0744,M,Membrane carboxypeptidase (penicillin-binding protein),5,8,16,13,42
COG0745,TK,Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain,2,55,142,50,249
COG0746,H,Molybdopterin-guanine dinucleotide biosynthesis protein A,0,0,12,2,14
COG0747,E,"ABC-type dipeptide transport system, periplasmic component",3,13,225,50,291
COG0748,P,Putative heme iron utilization protein,0,2,0,1,3
COG0749,L,DNA polymerase I - 3'-5' exonuclease and polymerase domains,2,13,17,7,39
COG0750,M,Predicted membrane-associated Zn-dependent proteases 1,0,5,16,1,22
COG0751,J,"Glycyl-tRNA synthetase, beta subunit",0,5,0,2,7
COG0752,J,"Glycyl-tRNA synthetase, alpha subunit",0,2,0,3,5
COG0753,P,Catalase,1,10,43,7,61
COG0754,E,Glutathionylspermidine synthase,0,0,23,1,24
COG0755,O,"ABC-type transport system involved in cytochrome c biogenesis, permease component",0,1,15,1,17
COG0756,F,dUTPase,2,2,12,1,17
COG0757,E,3-dehydroquinate dehydratase II,0,2,12,1,15
COG0758,LU,Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake,0,3,13,9,25
COG0759,S,Uncharacterized conserved protein,0,1,14,2,17
COG0760,O,Parvulin-like peptidyl-prolyl isomerase,0,3,0,3,6
COG0761,IM,Penicillin tolerance protein,0,4,25,5,34
COG0762,S,Predicted integral membrane protein,0,0,0,0,0
COG0763,M,Lipid A disaccharide synthetase,1,1,0,4,6
COG0764,I,3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases,0,2,0,0,2
COG0765,E,"ABC-type amino acid transport system, permease component",0,19,74,12,105
COG0766,M,UDP-N-acetylglucosamine enolpyruvyl transferase,7,4,22,16,49
COG0767,Q,"ABC-type transport system involved in resistance to organic solvents, permease component",0,2,0,8,10
COG0768,M,Cell division protein FtsI/penicillin-binding protein 2,0,16,49,21,86
COG0769,M,UDP-N-acetylmuramyl tripeptide synthase,1,4,18,7,30
COG0770,M,UDP-N-acetylmuramyl pentapeptide synthase,0,1,23,12,36
COG0771,M,UDP-N-acetylmuramoylalanine-D-glutamate ligase,0,3,17,15,35
COG0772,D,Bacterial cell division membrane protein,0,2,31,14,47
COG0773,M,UDP-N-acetylmuramate-alanine ligase,1,10,16,12,39
COG0774,M,UDP-3-O-acyl-N-acetylglucosamine deacetylase,1,4,0,7,12
COG0775,F,Nucleoside phosphorylase,0,1,15,2,18
COG0776,L,Bacterial nucleoid DNA-binding protein,0,4,24,3,31
COG0777,I,Acetyl-CoA carboxylase beta subunit,0,1,11,4,16
COG0778,C,Nitroreductase,1,3,30,12,46
COG0779,S,Uncharacterized protein conserved in bacteria,0,1,13,1,15
COG0780,R,Enzyme related to GTP cyclohydrolase I,0,0,0,3,3
COG0781,K,Transcription termination factor,0,2,22,7,31
COG0782,K,Transcription elongation factor,0,4,15,18,37
COG0783,P,DNA-binding ferritin-like protein (oxidative damage protectant),0,0,17,3,20
COG0784,T,FOG: CheY-like receiver,1,6,2,8,17
COG0785,O,Cytochrome c biogenesis protein,0,0,15,4,19
COG0786,E,Na+/glutamate symporter,0,0,0,0,0
COG0787,M,Alanine racemase,1,6,20,11,38
COG0788,F,Formyltetrahydrofolate hydrolase,0,2,57,11,70
COG0789,K,Predicted transcriptional regulators,0,7,94,2,103
COG0790,R,"FOG: TPR repeat, SEL1 subfamily",1,1,0,4,6
COG0791,M,Cell wall-associated hydrolases (invasion-associated proteins),0,3,24,1,28
COG0792,L,Predicted endonuclease distantly related to archaeal Holliday junction resolvase,0,1,10,2,13
COG0793,M,Periplasmic protease,1,13,2,24,40
COG0794,M,Predicted sugar phosphate isomerase involved in capsule formation,0,0,0,5,5
COG0795,R,Predicted permeases,0,4,0,10,14
COG0796,M,Glutamate racemase,0,4,17,19,40
COG0797,M,Lipoproteins,1,2,0,3,6
COG0798,P,Arsenite efflux pump ACR3 and related permeases,1,0,27,0,28
COG0799,S,Uncharacterized homolog of plant Iojap protein,0,1,14,2,17
COG0800,G,2-keto-3-deoxy-6-phosphogluconate aldolase,1,4,0,2,7
COG0801,H,"7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase",0,1,15,3,19
COG0802,R,Predicted ATPase or kinase,0,1,13,1,15
COG0803,P,"ABC-type metal ion transport system, periplasmic component/surface adhesin",0,2,49,6,57
COG0804,E,Urea amidohydrolase (urease) alpha subunit,0,3,19,7,29
COG0805,U,Sec-independent protein secretion pathway component TatC,2,2,17,6,27
COG0806,J,"RimM protein, required for 16S rRNA processing",0,1,14,2,17
COG0807,H,GTP cyclohydrolase II,1,3,0,6,10
COG0809,J,S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase),1,6,0,5,12
COG0810,M,"Periplasmic protein TonB, links inner and outer membranes",2,2,0,8,12
COG0811,U,Biopolymer transport proteins,2,5,2,6,15
COG0812,M,UDP-N-acetylmuramate dehydrogenase,1,1,7,5,14
COG0813,F,Purine-nucleoside phosphorylase,0,0,0,0,0
COG0814,E,Amino acid permeases,0,4,0,0,4
COG0815,M,Apolipoprotein N-acyltransferase,0,3,0,6,9
COG0816,L,Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis),0,2,16,5,23
COG0817,L,"Holliday junction resolvasome, endonuclease subunit",0,2,14,0,16
COG0818,M,Diacylglycerol kinase,0,1,0,2,3
COG0819,K,Putative transcription activator,0,0,0,2,2
COG0820,R,Predicted Fe-S-cluster redox enzyme,0,4,17,2,23
COG0821,I,Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis,1,2,13,4,20
COG0822,C,NifU homolog involved in Fe-S cluster formation,0,3,16,5,24
COG0823,U,Periplasmic component of the Tol biopolymer transport system,6,17,14,44,81
COG0824,R,Predicted thioesterase,5,7,58,9,79
COG0825,I,Acetyl-CoA carboxylase alpha subunit,1,4,3,7,15
COG0826,O,Collagenase and related proteases,0,5,0,0,5
COG0827,L,Adenine-specific DNA methylase,0,0,0,0,0
COG0828,J,Ribosomal protein S21,0,0,0,0,0
COG0829,O,Urease accessory protein UreH,0,1,27,5,33
COG0830,O,Urease accessory protein UreF,0,1,17,4,22
COG0831,E,Urea amidohydrolase (urease) gamma subunit,0,2,16,3,21
COG0832,E,Urea amidohydrolase (urease) beta subunit,0,1,16,2,19
COG0833,E,Amino acid transporters,1,5,37,14,57
COG0834,ET,"ABC-type amino acid transport/signal transduction systems, periplasmic component/domain",0,30,60,7,97
COG0835,NT,Chemotaxis signal transduction protein,0,11,0,1,12
COG0836,M,Mannose-1-phosphate guanylyltransferase,0,2,36,5,43
COG0837,G,Glucokinase,1,1,0,0,2
COG0838,C,NADH:ubiquinone oxidoreductase subunit 3 (chain A),1,3,0,5,9
COG0839,C,NADH:ubiquinone oxidoreductase subunit 6 (chain J),0,4,0,5,9
COG0840,NT,Methyl-accepting chemotaxis protein,0,37,0,2,39
COG0841,V,Cation/multidrug efflux pump,18,75,32,113,238
COG0842,V,"ABC-type multidrug transport system, permease component",0,3,0,3,6
COG0843,C,"Heme/copper-type cytochrome/quinol oxidases, subunit 1",3,18,22,31,74
COG0845,M,Membrane-fusion protein,1,10,16,18,45
COG0846,K,"NAD-dependent protein deacetylases, SIR2 family",0,1,16,3,20
COG0847,L,"DNA polymerase III, epsilon subunit and related 3'-5' exonucleases",0,2,27,2,31
COG0848,U,Biopolymer transport protein,2,6,0,9,17
COG0849,D,Actin-like ATPase involved in cell division,0,1,0,12,13
COG0850,D,Septum formation inhibitor,0,1,0,1,2
COG0851,D,Septum formation topological specificity factor,0,1,0,0,1
COG0852,C,NADH:ubiquinone oxidoreductase 27 kD subunit,0,1,0,13,14
COG0853,H,Aspartate 1-decarboxylase,0,0,14,2,16
COG0854,H,Pyridoxal phosphate biosynthesis protein,0,1,0,3,4
COG0855,P,Polyphosphate kinase,2,7,20,23,52
COG0856,F,Orotate phosphoribosyltransferase homologs,0,0,0,1,1
COG0857,R,BioD-like N-terminal domain of phosphotransacetylase,0,2,0,0,2
COG0858,J,Ribosome-binding factor A,0,2,5,2,9
COG0859,M,ADP-heptose:LPS heptosyltransferase,1,6,0,20,27
COG0860,M,N-acetylmuramoyl-L-alanine amidase,0,1,0,11,12
COG0861,P,"Membrane protein TerC, possibly involved in tellurium resistance",1,5,31,4,41
COG0863,L,DNA modification methylase,0,4,19,15,38
COG0864,K,Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain,0,0,0,1,1
COG1001,F,Adenine deaminase,0,0,0,1,1
COG1002,V,"Type II restriction enzyme, methylase subunits",0,0,0,0,0
COG1003,E,"Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain",0,5,10,8,23
COG1004,M,Predicted UDP-glucose 6-dehydrogenase,1,6,8,14,29
COG1005,C,NADH:ubiquinone oxidoreductase subunit 1 (chain H),0,2,0,9,11
COG1006,P,"Multisubunit Na+/H+ antiporter, MnhC subunit",0,1,14,1,16
COG1007,C,NADH:ubiquinone oxidoreductase subunit 2 (chain N),0,7,2,20,29
COG1008,C,NADH:ubiquinone oxidoreductase subunit 4 (chain M),3,8,3,11,25
COG1009,CP,"NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit",1,7,16,19,43
COG1010,H,Precorrin-3B methylase,0,1,1,3,5
COG1011,R,Predicted hydrolase (HAD superfamily),0,7,12,7,26
COG1012,C,NAD-dependent aldehyde dehydrogenases,9,83,367,94,553
COG1013,C,"Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit",1,3,3,13,20
COG1014,C,"Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit",0,0,0,3,3
COG1015,G,Phosphopentomutase,0,1,0,4,5
COG1017,C,Hemoglobin-like flavoprotein,0,1,28,0,29
COG1018,C,Flavodoxin reductases (ferredoxin-NADPH reductases) family 1,0,9,57,14,80
COG1019,R,Predicted nucleotidyltransferase,0,0,0,2,2
COG1020,Q,Non-ribosomal peptide synthetase modules and related proteins,1,234,29,43,307
COG1021,Q,Peptide arylation enzymes,2,0,0,3,5
COG1022,I,Long-chain acyl-CoA synthetases (AMP-forming),1,12,27,35,75
COG1023,G,Predicted 6-phosphogluconate dehydrogenase,1,3,0,5,9
COG1024,I,Enoyl-CoA hydratase/carnithine racemase,3,25,102,27,157
COG1025,O,"Secreted/periplasmic Zn-dependent peptidases, insulinase-like",0,1,0,0,1
COG1026,R,"Predicted Zn-dependent peptidases, insulinase-like",0,0,0,1,1
COG1027,E,Aspartate ammonia-lyase,1,3,29,7,40
COG1028,IQR,Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases),10,32,280,71,393
COG1029,C,Formylmethanofuran dehydrogenase subunit B,0,0,0,0,0
COG1030,O,Membrane-bound serine protease (ClpP class),0,1,0,7,8
COG1031,C,Uncharacterized Fe-S oxidoreductase,0,0,0,0,0
COG1032,C,Fe-S oxidoreductase,5,15,5,17,42
COG1033,R,Predicted exporters of the RND superfamily,0,5,0,4,9
COG1034,C,NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G),1,8,0,5,14
COG1035,C,"Coenzyme F420-reducing hydrogenase, beta subunit",0,0,0,0,0
COG1036,C,Archaeal flavoproteins,0,0,0,0,0
COG1038,C,Pyruvate carboxylase,0,2,28,4,34
COG1039,L,Ribonuclease HIII,0,0,0,3,3
COG1040,R,Predicted amidophosphoribosyltransferases,1,1,16,2,20
COG1041,L,Predicted DNA modification methylase,0,0,0,0,0
COG1042,C,Acyl-CoA synthetase (NDP forming),17,1,28,18,64
COG1043,M,Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase,0,2,10,9,21
COG1044,M,UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase,1,4,1,7,13
COG1045,E,Serine acetyltransferase,0,3,8,4,15
COG1047,O,FKBP-type peptidyl-prolyl cis-trans isomerases 2,0,3,1,1,5
COG1048,C,Aconitase A,10,10,25,22,67
COG1049,C,Aconitase B,0,5,0,0,5
COG1051,F,ADP-ribose pyrophosphatase,0,6,91,7,104
COG1052,CHR,Lactate dehydrogenase and related dehydrogenases,1,11,59,13,84
COG1053,C,"Succinate dehydrogenase/fumarate reductase, flavoprotein subunit",1,8,60,20,89
COG1054,R,Predicted sulfurtransferase,0,2,8,0,10
COG1055,P,Na+/H+ antiporter NhaD and related arsenite permeases,0,2,17,4,23
COG1056,H,Nicotinamide mononucleotide adenylyltransferase,0,1,0,4,5
COG1057,H,Nicotinic acid mononucleotide adenylyltransferase,0,5,15,7,27
COG1058,R,Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA,0,1,0,6,7
COG1059,L,Thermostable 8-oxoguanine DNA glycosylase,0,1,0,0,1
COG1060,HR,Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes,0,3,5,23,31
COG1061,KL,DNA or RNA helicases of superfamily II,0,4,11,9,24
COG1062,C,"Zn-dependent alcohol dehydrogenases, class III",1,5,137,26,169
COG1063,ER,Threonine dehydrogenase and related Zn-dependent dehydrogenases,3,8,45,26,82
COG1064,R,Zn-dependent alcohol dehydrogenases,7,9,59,65,140
COG1066,O,Predicted ATP-dependent serine protease,0,3,15,2,20
COG1067,O,Predicted ATP-dependent protease,0,2,0,1,3
COG1069,C,Ribulose kinase,0,0,0,0,0
COG1070,G,Sugar (pentulose and hexulose) kinases,0,6,44,12,62
COG1071,C,"Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit",5,7,40,29,81
COG1072,H,Panthothenate kinase,5,2,18,3,28
COG1073,R,Hydrolases of the alpha/beta superfamily,0,0,0,0,0
COG1074,L,ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains),1,9,2,8,20
COG1075,R,Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold,0,2,12,0,14
COG1076,O,DnaJ-domain-containing proteins 1,0,1,0,0,1
COG1077,D,Actin-like ATPase involved in cell morphogenesis,7,4,0,6,17
COG1078,R,HD superfamily phosphohydrolases,0,1,1,18,20
COG1079,R,"Uncharacterized ABC-type transport system, permease component",0,1,26,3,30
COG1080,G,Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria),0,12,20,11,43
COG1082,G,Sugar phosphate isomerases/epimerases,0,3,20,14,37
COG1083,M,CMP-N-acetylneuraminic acid synthetase,0,1,16,3,20
COG1084,R,Predicted GTPase,0,0,0,0,0
COG1085,C,Galactose-1-phosphate uridylyltransferase,1,0,18,5,24
COG1086,MG,Predicted nucleoside-diphosphate sugar epimerases,0,2,0,13,15
COG1087,M,UDP-glucose 4-epimerase,1,8,18,12,39
COG1088,M,"dTDP-D-glucose 4,6-dehydratase",1,7,13,15,36
COG1089,M,GDP-D-mannose dehydratase,0,2,0,8,10
COG1090,R,Predicted nucleoside-diphosphate sugar epimerase,1,3,42,18,64
COG1091,M,dTDP-4-dehydrorhamnose reductase,0,3,12,6,21
COG1092,R,Predicted SAM-dependent methyltransferases,0,9,2,7,18
COG1093,J,"Translation initiation factor 2, alpha subunit (eIF-2alpha)",0,0,0,3,3
COG1094,R,Predicted RNA-binding protein (contains KH domains),0,0,0,1,1
COG1095,K,"DNA-directed RNA polymerase, subunit E'",0,0,0,2,2
COG1096,J,Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain),0,0,0,1,1
COG1097,J,RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain),0,0,0,3,3
COG1098,J,Predicted RNA binding protein (contains ribosomal protein S1 domain),0,0,0,0,0
COG1099,R,Predicted metal-dependent hydrolases with the TIM-barrel fold,0,0,2,4,6
COG1100,R,GTPase SAR1 and related small G proteins,0,0,1,2,3
COG1101,R,"ABC-type uncharacterized transport system, ATPase component",0,0,20,7,27
COG1102,F,Cytidylate kinase,0,0,0,2,2
COG1103,R,Archaea-specific pyridoxal phosphate-dependent enzymes,0,0,0,0,0
COG1104,E,Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes,1,7,39,12,59
COG1105,G,Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB),0,1,16,1,18
COG1106,R,Predicted ATPases,0,2,0,0,2
COG1107,L,"Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain",0,0,0,0,0
COG1108,P,"ABC-type Mn2+/Zn2+ transport systems, permease components",0,1,45,7,53
COG1109,G,Phosphomannomutase,9,15,48,22,94
COG1110,L,Reverse gyrase,0,0,0,0,0
COG1111,L,ERCC4-like helicases,0,0,2,5,7
COG1112,L,Superfamily I DNA and RNA helicases and helicase subunits,0,0,13,0,13
COG1113,E,Gamma-aminobutyrate permease and related permeases,0,14,116,3,133
COG1114,E,Branched-chain amino acid permeases,0,3,0,0,3
COG1115,E,Na+/alanine symporter,1,3,15,0,19
COG1116,P,"ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component",2,9,105,15,131
COG1117,P,"ABC-type phosphate transport system, ATPase component",2,1,16,8,27
COG1118,P,"ABC-type sulfate/molybdate transport systems, ATPase component",0,2,13,0,15
COG1119,P,"ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA",0,0,30,0,30
COG1120,PH,"ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components",0,7,37,8,52
COG1121,P,"ABC-type Mn/Zn transport systems, ATPase component",0,3,46,6,55
COG1122,P,"ABC-type cobalt transport system, ATPase component",0,0,32,1,33
COG1123,R,"ATPase components of various ABC-type transport systems, contain duplicated ATPase",0,3,184,5,192
COG1124,EP,"ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component",0,0,1,0,1
COG1125,E,"ABC-type proline/glycine betaine transport systems, ATPase components",0,1,34,4,39
COG1126,E,"ABC-type polar amino acid transport system, ATPase component",1,19,72,5,97
COG1127,Q,"ABC-type transport system involved in resistance to organic solvents, ATPase component",1,2,2,10,15
COG1129,G,"ABC-type sugar transport system, ATPase component",4,11,94,25,134
COG1131,V,"ABC-type multidrug transport system, ATPase component",6,14,115,47,182
COG1132,V,"ABC-type multidrug transport system, ATPase and permease components",18,19,114,33,184
COG1133,I,"ABC-type long-chain fatty acid transport system, fused permease and ATPase components",0,0,0,0,0
COG1134,GM,"ABC-type polysaccharide/polyol phosphate transport system, ATPase component",2,2,14,5,23
COG1135,P,"ABC-type metal ion transport system, ATPase component",0,2,27,1,30
COG1136,V,"ABC-type antimicrobial peptide transport system, ATPase component",8,12,96,41,157
COG1137,R,"ABC-type (unclassified) transport system, ATPase component",1,3,0,8,12
COG1138,O,Cytochrome c biogenesis factor,0,7,0,1,8
COG1139,C,Uncharacterized conserved protein containing a ferredoxin-like domain,0,2,15,2,19
COG1140,C,Nitrate reductase beta subunit,3,2,0,2,7
COG1141,C,Ferredoxin,0,1,0,0,1
COG1142,C,Fe-S-cluster-containing hydrogenase components 2,0,0,0,0,0
COG1143,C,Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I),1,2,7,9,19
COG1144,C,"Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit",0,0,0,0,0
COG1145,C,Ferredoxin,0,0,0,0,0
COG1146,C,Ferredoxin,0,1,14,4,19
COG1148,C,"Heterodisulfide reductase, subunit A and related polyferredoxins",0,0,1,0,1
COG1149,C,MinD superfamily P-loop ATPase containing an inserted ferredoxin domain,0,0,0,0,0
COG1150,C,"Heterodisulfide reductase, subunit C",0,0,0,0,0
COG1151,C,6Fe-6S prismane cluster-containing protein,0,0,0,0,0
COG1152,C,CO dehydrogenase/acetyl-CoA synthase alpha subunit,0,0,0,0,0
COG1153,C,Formylmethanofuran dehydrogenase subunit D,0,0,0,0,0
COG1154,HI,Deoxyxylulose-5-phosphate synthase,1,10,22,16,49
COG1155,C,Archaeal/vacuolar-type H+-ATPase subunit A,0,0,5,3,8
COG1156,C,Archaeal/vacuolar-type H+-ATPase subunit B,0,0,3,3,6
COG1157,NU,Flagellar biosynthesis/type III secretory pathway ATPase,0,4,0,1,5
COG1158,K,Transcription termination factor,5,2,20,11,38
COG1159,R,GTPase,0,4,14,2,20
COG1160,R,Predicted GTPases,2,11,18,6,37
COG1161,R,Predicted GTPases,0,0,0,0,0
COG1162,R,Predicted GTPases,0,1,14,1,16
COG1163,R,Predicted GTPase,0,0,1,2,3
COG1164,E,Oligoendopeptidase F,1,2,2,13,18
COG1165,H,"2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase",0,0,11,1,12
COG1166,E,Arginine decarboxylase (spermidine biosynthesis),2,5,0,12,19
COG1167,KE,Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs,2,22,15,13,52
COG1168,E,Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities,0,2,0,2,4
COG1169,HQ,Isochorismate synthase,0,0,17,1,18
COG1171,E,Threonine dehydratase,2,8,15,13,38
COG1172,G,"Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components",2,7,76,4,89
COG1173,EP,"ABC-type dipeptide/oligopeptide/nickel transport systems, permease components",1,5,177,32,215
COG1174,E,"ABC-type proline/glycine betaine transport systems, permease component",0,5,65,6,76
COG1175,G,"ABC-type sugar transport systems, permease components",1,4,53,26,84
COG1176,E,"ABC-type spermidine/putrescine transport system, permease component I",0,11,16,11,38
COG1177,E,"ABC-type spermidine/putrescine transport system, permease component II",0,7,30,4,41
COG1178,P,"ABC-type Fe3+ transport system, permease component",2,11,0,7,20
COG1179,H,Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1,0,2,0,0,2
COG1180,O,Pyruvate-formate lyase-activating enzyme,0,4,2,4,10
COG1181,M,D-alanine-D-alanine ligase and related ATP-grasp enzymes,1,18,19,10,48
COG1182,I,Acyl carrier protein phosphodiesterase,0,4,0,1,5
COG1183,I,Phosphatidylserine synthase,0,4,0,2,6
COG1184,J,"Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family",0,0,0,0,0
COG1185,J,Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase),1,8,25,13,47
COG1186,J,Protein chain release factor B,0,4,27,6,37
COG1187,J,16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases,0,9,18,3,30
COG1188,J,Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog),0,1,9,7,17
COG1189,J,Predicted rRNA methylase,0,1,14,0,15
COG1190,J,Lysyl-tRNA synthetase (class II),0,3,33,15,51
COG1191,K,DNA-directed RNA polymerase specialized sigma subunit,0,1,0,3,4
COG1192,D,ATPases involved in chromosome partitioning,0,6,63,18,87
COG1193,L,Mismatch repair ATPase (MutS family),1,1,0,10,12
COG1194,L,A/G-specific DNA glycosylase,0,1,15,2,18
COG1195,L,Recombinational DNA repair ATPase (RecF pathway),0,4,15,2,21
COG1196,D,Chromosome segregation ATPases,3,6,47,17,73
COG1197,LK,Transcription-repair coupling factor (superfamily II helicase),5,12,25,24,66
COG1198,L,Primosomal protein N' (replication factor Y) - superfamily II helicase,0,5,20,10,35
COG1199,KL,Rad3-related DNA helicases,1,7,20,11,39
COG1200,LK,RecG-like helicase,0,4,16,22,42
COG1201,R,Lhr-like helicases,0,6,19,27,52
COG1202,R,"Superfamily II helicase, archaea-specific",0,0,0,0,0
COG1203,R,Predicted helicases,0,0,0,0,0
COG1204,R,Superfamily II helicase,0,0,1,4,5
COG1205,R,Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster,0,1,22,1,24
COG1206,J,NAD(FAD)-utilizing enzyme possibly involved in translation,1,0,0,2,3
COG1207,M,N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains),2,6,23,6,37
COG1208,MJ,"Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)",4,6,1,18,29
COG1209,M,dTDP-glucose pyrophosphorylase,5,1,13,13,32
COG1210,M,UDP-glucose pyrophosphorylase,0,1,14,6,21
COG1211,I,4-diphosphocytidyl-2-methyl-D-erithritol synthase,5,3,4,1,13
COG1212,M,CMP-2-keto-3-deoxyoctulosonic acid synthetase,0,2,0,3,5
COG1213,M,Predicted sugar nucleotidyltransferases,0,0,0,2,2
COG1214,O,"Inactive homolog of metal-dependent proteases, putative molecular chaperone",0,1,13,1,15
COG1215,M,"Glycosyltransferases, probably involved in cell wall biogenesis",1,10,36,28,75
COG1216,R,Predicted glycosyltransferases,0,5,46,9,60
COG1217,T,Predicted membrane GTPase involved in stress response,7,3,32,12,54
COG1218,P,3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase,0,4,0,1,5
COG1219,O,"ATP-dependent protease Clp, ATPase subunit",5,7,17,8,37
COG1220,O,"ATP-dependent protease HslVU (ClpYQ), ATPase subunit",6,5,0,2,13
COG1221,KT,Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain,0,1,0,0,1
COG1222,O,ATP-dependent 26S proteasome regulatory subunit,0,0,30,10,40
COG1223,R,Predicted ATPase (AAA+ superfamily),0,0,0,0,0
COG1224,K,"DNA helicase TIP49, TBP-interacting protein",0,0,0,0,0
COG1225,O,Peroxiredoxin,7,6,46,39,98
COG1226,P,"Kef-type K+ transport systems, predicted NAD-binding component",0,2,0,0,2
COG1227,C,Inorganic pyrophosphatase/exopolyphosphatase,0,0,0,0,0
COG1228,Q,Imidazolonepropionase and related amidohydrolases,2,10,38,36,86
COG1229,C,Formylmethanofuran dehydrogenase subunit A,0,0,0,0,0
COG1230,P,Co/Zn/Cd efflux system component,3,3,22,17,45
COG1231,E,Monoamine oxidase,0,1,27,4,32
COG1232,H,Protoporphyrinogen oxidase,0,4,20,8,32
COG1233,Q,Phytoene dehydrogenase and related proteins,1,5,65,19,90
COG1234,R,Metal-dependent hydrolases of the beta-lactamase superfamily III,1,2,70,12,85
COG1235,R,Metal-dependent hydrolases of the beta-lactamase superfamily I,0,6,1,11,18
COG1236,J,Predicted exonuclease of the beta-lactamase fold involved in RNA processing,0,3,1,6,10
COG1237,R,Metal-dependent hydrolases of the beta-lactamase superfamily II,0,1,0,7,8
COG1238,S,Predicted membrane protein,0,1,0,0,1
COG1239,H,Mg-chelatase subunit ChlI,0,6,2,2,10
COG1240,H,Mg-chelatase subunit ChlD,0,3,0,3,6
COG1241,L,"Predicted ATPase involved in replication control, Cdc46/Mcm family",0,0,3,8,11
COG1242,R,Predicted Fe-S oxidoreductase,0,0,0,0,0
COG1243,KB,Histone acetyltransferase,0,0,3,2,5
COG1244,R,Predicted Fe-S oxidoreductase,0,1,0,0,1
COG1245,R,"Predicted ATPase, RNase L inhibitor (RLI) homolog",0,0,4,6,10
COG1246,E,N-acetylglutamate synthase and related acetyltransferases,1,2,16,3,22
COG1247,M,Sortase and related acyltransferases,0,2,20,1,23
COG1249,C,"Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes",0,12,94,44,150
COG1250,I,3-hydroxyacyl-CoA dehydrogenase,1,8,44,28,81
COG1251,C,NAD(P)H-nitrite reductase,0,10,119,12,141
COG1252,C,"NADH dehydrogenase, FAD-containing subunit",1,5,16,36,58
COG1253,R,Hemolysins and related proteins containing CBS domains,6,2,60,22,90
COG1254,C,Acylphosphatases,0,0,1,3,4
COG1255,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1256,N,Flagellar hook-associated protein,0,1,0,0,1
COG1257,I,Hydroxymethylglutaryl-CoA reductase,0,1,2,3,6
COG1258,J,Predicted pseudouridylate synthase,0,0,0,2,2
COG1259,S,Uncharacterized conserved protein,0,0,16,3,19
COG1260,I,Myo-inositol-1-phosphate synthase,0,2,17,11,30
COG1261,NO,Flagellar basal body P-ring biosynthesis protein,0,2,0,0,2
COG1262,S,Uncharacterized conserved protein,0,4,0,21,25
COG1263,G,"Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific",0,3,0,0,3
COG1264,G,Phosphotransferase system IIB components,0,0,0,0,0
COG1266,R,Predicted metal-dependent membrane protease,0,0,13,0,13
COG1267,I,Phosphatidylglycerophosphatase A and related proteins,0,1,0,1,2
COG1268,R,Uncharacterized conserved protein,1,1,11,0,13
COG1269,C,Archaeal/vacuolar-type H+-ATPase subunit I,0,0,2,3,5
COG1270,H,Cobalamin biosynthesis protein CobD/CbiB,0,0,0,5,5
COG1271,C,"Cytochrome bd-type quinol oxidase, subunit 1",1,4,19,6,30
COG1272,R,"Predicted membrane protein, hemolysin III homolog",0,1,10,1,12
COG1273,S,Uncharacterized conserved protein,4,5,4,17,30
COG1274,C,Phosphoenolpyruvate carboxykinase (GTP),0,0,13,8,21
COG1275,P,Tellurite resistance protein and related permeases,0,1,6,0,7
COG1276,P,Putative copper export protein,0,3,12,2,17
COG1277,R,"ABC-type transport system involved in multi-copper enzyme maturation, permease component",0,0,0,0,0
COG1278,K,Cold shock proteins,1,8,42,4,55
COG1279,R,Lysine efflux permease,0,1,12,1,14
COG1280,E,Putative threonine efflux protein,0,11,48,2,61
COG1281,O,Disulfide bond chaperones of the HSP33 family,0,2,0,1,3
COG1282,C,NAD/NADP transhydrogenase beta subunit,0,4,0,10,14
COG1283,P,Na+/phosphate symporter,0,2,0,1,3
COG1284,S,Uncharacterized conserved protein,0,0,0,1,1
COG1285,S,Uncharacterized membrane protein,0,0,0,0,0
COG1286,R,"Uncharacterized membrane protein, required for colicin V production",0,0,0,0,0
COG1287,R,"Uncharacterized membrane protein, required for N-linked glycosylation",2,0,0,2,4
COG1288,S,Predicted membrane protein,0,0,0,0,0
COG1289,S,Predicted membrane protein,0,13,25,1,39
COG1290,C,Cytochrome b subunit of the bc complex,2,2,18,23,45
COG1291,N,Flagellar motor component,0,4,0,0,4
COG1292,M,Choline-glycine betaine transporter,0,4,59,5,68
COG1293,K,Predicted RNA-binding protein homologous to eukaryotic snRNP,0,1,1,2,4
COG1294,C,"Cytochrome bd-type quinol oxidase, subunit 2",0,2,16,3,21
COG1295,S,Predicted membrane protein,1,5,29,8,43
COG1296,E,Predicted branched-chain amino acid permease (azaleucine resistance),0,2,14,0,16
COG1297,S,Predicted membrane protein,0,2,0,10,12
COG1298,NU,"Flagellar biosynthesis pathway, component FlhA",0,3,0,2,5
COG1299,G,"Phosphotransferase system, fructose-specific IIC component",0,1,16,1,18
COG1300,S,Uncharacterized membrane protein,0,1,0,1,2
COG1301,C,Na+/H+-dicarboxylate symporters,1,8,64,11,84
COG1302,S,Uncharacterized protein conserved in bacteria,0,0,28,0,28
COG1303,S,Uncharacterized protein conserved in archaea,0,0,1,3,4
COG1304,C,L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases,0,2,19,15,36
COG1305,E,"Transglutaminase-like enzymes, putative cysteine proteases",2,1,8,5,16
COG1306,S,Uncharacterized conserved protein,0,0,0,1,1
COG1307,S,Uncharacterized protein conserved in bacteria,0,0,15,2,17
COG1308,K,Transcription factor homologous to NACalpha-BTF3,0,0,0,2,2
COG1309,K,Transcriptional regulator,2,15,284,10,311
COG1310,R,Predicted metal-dependent protease of the PAD1/JAB1 superfamily,0,2,0,4,6
COG1311,L,"Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B",0,0,2,3,5
COG1312,G,D-mannonate dehydratase,0,0,0,0,0
COG1313,R,"Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins",0,0,0,5,5
COG1314,U,Preprotein translocase subunit SecG,0,2,0,1,3
COG1315,L,"Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain",0,0,0,0,0
COG1316,K,Transcriptional regulator,0,0,61,14,75
COG1317,NU,Flagellar biosynthesis/type III secretory pathway protein,0,1,0,0,1
COG1318,K,Predicted transcriptional regulators,0,0,0,0,0
COG1319,C,"Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs",1,5,0,5,11
COG1320,P,"Multisubunit Na+/H+ antiporter, MnhG subunit",0,0,14,0,14
COG1321,K,Mn-dependent transcriptional regulator,0,0,38,6,44
COG1322,S,Uncharacterized protein conserved in bacteria,0,1,16,8,25
COG1323,R,Predicted nucleotidyltransferase,0,0,0,0,0
COG1324,P,Uncharacterized protein involved in tolerance to divalent cations,0,0,0,3,3
COG1325,J,Predicted exosome subunit,0,0,0,1,1
COG1326,R,Uncharacterized archaeal Zn-finger protein,0,0,0,0,0
COG1327,K,"Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains",0,1,15,3,19
COG1328,F,Oxygen-sensitive ribonucleoside-triphosphate reductase,0,2,0,2,4
COG1329,K,"Transcriptional regulators, similar to M. xanthus CarD",3,1,16,4,24
COG1330,L,Exonuclease V gamma subunit,0,7,0,6,13
COG1331,O,Highly conserved protein containing a thioredoxin domain,6,1,17,23,47
COG1332,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1333,O,ResB protein required for cytochrome c biosynthesis,0,0,26,0,26
COG1334,N,Uncharacterized flagellar protein FlaG,0,0,0,0,0
COG1335,Q,Amidases related to nicotinamidase,1,8,53,12,74
COG1336,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1337,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1338,NU,"Flagellar biosynthesis pathway, component FliP",0,1,0,0,1
COG1339,KH,Transcriptional regulator of a riboflavin/FAD biosynthetic operon,0,0,0,5,5
COG1340,S,Uncharacterized archaeal coiled-coil protein,0,0,0,0,0
COG1341,R,Predicted GTPase or GTP-binding protein,0,0,0,0,0
COG1342,R,Predicted DNA-binding proteins,0,0,0,0,0
COG1343,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG1344,N,Flagellin and related hook-associated proteins,0,2,0,0,2
COG1345,N,Flagellar capping protein,0,0,0,0,0
COG1346,M,Putative effector of murein hydrolase,0,2,0,0,2
COG1347,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD",0,0,0,0,0
COG1348,P,Nitrogenase subunit NifH (ATPase),0,0,0,0,0
COG1349,KG,Transcriptional regulators of sugar metabolism,0,2,19,4,25
COG1350,R,Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB),0,0,0,1,1
COG1351,F,Predicted alternative thymidylate synthase,0,1,1,3,5
COG1352,NT,Methylase of chemotaxis methyl-accepting proteins,0,7,0,3,10
COG1353,R,Predicted hydrolase of the HD superfamily (permuted catalytic motifs),0,0,0,0,0
COG1354,S,Uncharacterized conserved protein,0,1,15,3,19
COG1355,R,Predicted dioxygenase,0,0,1,4,5
COG1356,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1357,S,Uncharacterized low-complexity proteins,0,2,16,5,23
COG1358,J,Ribosomal protein HS6-type (S12/L30/L7a),0,0,0,1,1
COG1359,S,Uncharacterized conserved protein,0,2,15,1,18
COG1360,N,Flagellar motor protein,0,1,0,2,3
COG1361,M,S-layer domain,0,0,0,0,0
COG1362,E,Aspartyl aminopeptidase,0,2,14,2,18
COG1363,G,Cellulase M and related proteins,0,3,0,6,9
COG1364,E,N-acetylglutamate synthase (N-acetylornithine aminotransferase),4,2,10,1,17
COG1365,R,Predicted ATPase (PP-loop superfamily),0,0,0,0,0
COG1366,T,Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor),0,3,0,10,13
COG1367,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1368,M,"Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily",0,4,0,0,4
COG1369,J,RNase P/RNase MRP subunit POP5,0,0,0,0,0
COG1370,O,"Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit",0,0,0,2,2
COG1371,S,Uncharacterized conserved protein,0,0,0,4,4
COG1372,L,Intein/homing endonuclease,0,0,0,0,0
COG1373,R,Predicted ATPase (AAA+ superfamily),0,0,0,0,0
COG1374,J,"Protein involved in ribosomal biogenesis, contains PUA domain",0,0,0,0,0
COG1376,S,Uncharacterized protein conserved in bacteria,0,2,0,10,12
COG1377,NU,"Flagellar biosynthesis pathway, component FlhB",0,2,0,0,2
COG1378,K,Predicted transcriptional regulators,0,0,0,2,2
COG1379,S,Uncharacterized conserved protein,0,0,0,0,0
COG1380,R,Putative effector of murein hydrolase LrgA,0,2,0,0,2
COG1381,L,Recombinational DNA repair protein (RecF pathway),0,2,17,3,22
COG1382,O,"Prefoldin, chaperonin cofactor",0,0,1,1,2
COG1383,J,Ribosomal protein S17E,0,0,0,2,2
COG1384,J,Lysyl-tRNA synthetase (class I),0,0,2,3,5
COG1385,S,Uncharacterized protein conserved in bacteria,0,4,15,1,20
COG1386,K,Predicted transcriptional regulator containing the HTH domain,0,0,15,3,18
COG1387,ER,Histidinol phosphatase and related hydrolases of the PHP family,0,2,0,8,10
COG1388,M,FOG: LysM repeat,0,1,0,0,1
COG1389,L,"DNA topoisomerase VI, subunit B",0,0,0,4,4
COG1390,C,Archaeal/vacuolar-type H+-ATPase subunit E,0,0,0,1,1
COG1391,OT,Glutamine synthetase adenylyltransferase,0,4,17,29,50
COG1392,P,Phosphate transport regulator (distant homolog of PhoU),0,0,0,6,6
COG1393,P,"Arsenate reductase and related proteins, glutaredoxin family",0,0,0,0,0
COG1394,C,Archaeal/vacuolar-type H+-ATPase subunit D,0,0,0,4,4
COG1395,K,Predicted transcriptional regulator,0,0,0,0,0
COG1396,K,Predicted transcriptional regulators,0,1,28,1,30
COG1397,O,ADP-ribosylglycohydrolase,0,1,15,1,17
COG1398,I,Fatty-acid desaturase,3,3,0,11,17
COG1399,R,"Predicted metal-binding, possibly nucleic acid-binding protein",0,3,14,0,17
COG1400,U,Signal recognition particle 19 kDa protein,0,0,0,1,1
COG1401,V,GTPase subunit of restriction endonuclease,0,0,0,0,0
COG1402,R,"Uncharacterized protein, putative amidase",0,1,10,8,19
COG1403,V,Restriction endonuclease,0,4,2,6,12
COG1404,O,Subtilisin-like serine proteases,0,5,20,0,25
COG1405,K,"Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB",0,0,6,15,21
COG1406,N,"Predicted inhibitor of MCP methylation, homolog of CheC",0,0,0,0,0
COG1407,R,Predicted ICC-like phosphoesterases,0,0,0,1,1
COG1408,R,Predicted phosphohydrolases,2,1,12,4,19
COG1409,R,Predicted phosphohydrolases,2,5,21,12,40
COG1410,E,"Methionine synthase I, cobalamin-binding domain",0,7,3,15,25
COG1411,R,Uncharacterized protein related to proFAR isomerase (HisA),0,0,0,0,0
COG1412,R,Uncharacterized proteins of PilT N-term./Vapc superfamily,0,0,0,1,1
COG1413,C,FOG: HEAT repeat,0,1,0,1,2
COG1414,K,Transcriptional regulator,0,9,257,12,278
COG1415,S,Uncharacterized conserved protein,0,0,0,2,2
COG1416,S,Uncharacterized conserved protein,0,0,0,1,1
COG1417,S,Uncharacterized conserved protein,0,0,0,0,0
COG1418,R,Predicted HD superfamily hydrolase,0,0,0,15,15
COG1419,N,Flagellar GTP-binding protein,0,2,0,0,2
COG1420,K,Transcriptional regulator of heat shock gene,1,2,15,3,21
COG1421,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG1422,S,Predicted membrane protein,0,0,0,2,2
COG1423,L,"ATP-dependent DNA ligase, homolog of eukaryotic ligase III",0,0,0,0,0
COG1424,H,Pimeloyl-CoA synthetase,0,0,0,0,0
COG1426,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG1427,R,Predicted periplasmic solute-binding protein,0,1,0,5,6
COG1428,F,Deoxynucleoside kinases,0,0,0,1,1
COG1429,H,Cobalamin biosynthesis protein CobN and related Mg-chelatases,0,7,0,2,9
COG1430,S,Uncharacterized conserved protein,0,0,0,2,2
COG1431,J,Uncharacterized protein containing piwi/argonaute domain,0,0,0,0,0
COG1432,S,Uncharacterized conserved protein,3,2,12,3,20
COG1433,S,Uncharacterized conserved protein,0,0,0,0,0
COG1434,S,Uncharacterized conserved protein,0,0,13,1,14
COG1435,F,Thymidine kinase,0,0,15,2,17
COG1436,C,Archaeal/vacuolar-type H+-ATPase subunit F,0,0,0,1,1
COG1437,F,"Adenylate cyclase, class 2 (thermophilic)",0,0,0,2,2
COG1438,K,Arginine repressor,0,0,7,0,7
COG1439,R,"Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module",0,0,0,0,0
COG1440,G,Phosphotransferase system cellobiose-specific component IIB,0,0,0,0,0
COG1441,H,O-succinylbenzoate synthase,0,0,0,0,0
COG1442,M,"Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases",0,0,0,1,1
COG1443,I,Isopentenyldiphosphate isomerase,0,2,31,3,36
COG1444,R,Predicted P-loop ATPase fused to an acetyltransferase,0,0,0,0,0
COG1445,G,Phosphotransferase system fructose-specific component IIB,0,0,1,1,2
COG1446,E,Asparaginase,0,0,0,6,6
COG1447,G,Phosphotransferase system cellobiose-specific component IIA,0,0,0,0,0
COG1448,E,Aspartate/tyrosine/aromatic aminotransferase,0,4,0,0,4
COG1449,G,Alpha-amylase/alpha-mannosidase,0,0,0,1,1
COG1450,NU,"Type II secretory pathway, component PulD",1,2,0,5,8
COG1451,R,Predicted metal-dependent hydrolase,0,2,13,2,17
COG1452,M,Organic solvent tolerance protein OstA,0,6,0,0,6
COG1453,R,Predicted oxidoreductases of the aldo/keto reductase family,0,2,0,1,3
COG1454,C,"Alcohol dehydrogenase, class IV",0,13,0,13,26
COG1455,G,Phosphotransferase system cellobiose-specific component IIC,0,0,0,0,0
COG1456,C,CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein),0,0,0,0,0
COG1457,F,Purine-cytosine permease and related proteins,0,16,0,2,18
COG1458,R,Predicted DNA-binding protein containing PIN domain,0,0,0,0,0
COG1459,NU,"Type II secretory pathway, component PulF",0,20,0,9,29
COG1460,S,Uncharacterized protein conserved in archaea,0,0,0,1,1
COG1461,R,Predicted kinase related to dihydroxyacetone kinase,0,0,17,1,18
COG1462,M,Uncharacterized protein involved in formation of curli polymers,0,0,0,0,0
COG1463,Q,"ABC-type transport system involved in resistance to organic solvents, periplasmic component",1,3,0,12,16
COG1464,P,"ABC-type metal ion transport system, periplasmic component/surface antigen",0,1,27,0,28
COG1465,E,Predicted alternative 3-dehydroquinate synthase,0,0,1,2,3
COG1466,L,"DNA polymerase III, delta subunit",1,1,21,6,29
COG1467,L,"Eukaryotic-type DNA primase, catalytic (small) subunit",0,0,0,1,1
COG1468,L,RecB family exonuclease,0,0,0,0,0
COG1469,S,Uncharacterized conserved protein,0,1,0,0,1
COG1470,S,Predicted membrane protein,0,0,0,0,0
COG1471,J,Ribosomal protein S4E,0,0,0,3,3
COG1472,G,Beta-glucosidase-related glycosidases,1,9,47,13,70
COG1473,R,Metal-dependent amidase/aminoacylase/carboxypeptidase,0,2,68,9,79
COG1474,LO,"Cdc6-related protein, AAA superfamily ATPase",0,0,0,4,4
COG1475,K,Predicted transcriptional regulators,0,3,24,5,32
COG1476,K,Predicted transcriptional regulators,0,1,15,1,17
COG1477,H,Membrane-associated lipoprotein involved in thiamine biosynthesis,0,1,0,2,3
COG1478,S,Uncharacterized conserved protein,0,1,2,18,21
COG1479,S,Uncharacterized conserved protein,0,0,0,0,0
COG1480,R,Predicted membrane-associated HD superfamily hydrolase,0,1,0,3,4
COG1481,S,Uncharacterized protein conserved in bacteria,0,0,31,0,31
COG1482,G,Phosphomannose isomerase,1,0,19,3,23
COG1483,R,Predicted ATPase (AAA+ superfamily),0,0,0,1,1
COG1484,L,DNA replication protein,0,0,9,5,14
COG1485,R,Predicted ATPase,0,5,31,0,36
COG1486,G,"Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases",0,1,0,0,1
COG1487,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,0,0
COG1488,H,Nicotinic acid phosphoribosyltransferase,1,3,25,4,33
COG1489,R,"DNA-binding protein, stimulates sugar fermentation",0,1,0,0,1
COG1490,J,D-Tyr-tRNAtyr deacylase,0,1,15,0,16
COG1491,J,Predicted RNA-binding protein,0,0,1,3,4
COG1492,H,Cobyric acid synthase,0,1,1,9,11
COG1493,T,"Serine kinase of the HPr protein, regulates carbohydrate metabolism",0,1,0,4,5
COG1494,G,"Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins",0,2,16,3,21
COG1495,O,Disulfide bond formation protein DsbB,0,1,0,0,1
COG1496,S,Uncharacterized conserved protein,0,1,16,3,20
COG1497,K,Predicted transcriptional regulator,0,0,0,0,0
COG1498,J,"Protein implicated in ribosomal biogenesis, Nop56p homolog",1,0,1,4,6
COG1499,J,NMD protein affecting ribosome stability and mRNA decay,0,0,0,0,0
COG1500,J,Predicted exosome subunit,0,0,1,2,3
COG1501,G,"Alpha-glucosidases, family 31 of glycosyl hydrolases",0,1,0,8,9
COG1502,I,Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes,3,15,16,17,51
COG1503,J,Peptide chain release factor 1 (eRF1),0,0,0,4,4
COG1504,S,Uncharacterized conserved protein,0,0,0,0,0
COG1505,E,Serine proteases of the peptidase family S9A,10,4,17,8,39
COG1506,E,Dipeptidyl aminopeptidases/acylaminoacyl-peptidases,12,26,46,24,108
COG1507,S,Uncharacterized conserved protein,0,0,13,0,13
COG1508,K,"DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog",0,4,0,6,10
COG1509,E,"Lysine 2,3-aminomutase",0,4,0,3,7
COG1510,K,Predicted transcriptional regulators,0,0,0,0,0
COG1511,S,Predicted membrane protein,0,0,23,1,24
COG1512,R,Beta-propeller domains of methanol dehydrogenase type,0,4,12,4,20
COG1513,P,Cyanate lyase,0,0,0,0,0
COG1514,J,2'-5' RNA ligase,0,2,10,4,16
COG1515,L,Deoxyinosine 3'endonuclease (endonuclease V),0,0,2,2,4
COG1516,NUO,Flagellin-specific chaperone FliS,0,1,0,0,1
COG1517,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG1518,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG1519,M,3-deoxy-D-manno-octulosonic-acid transferase,1,1,0,7,9
COG1520,S,FOG: WD40-like repeat,0,15,0,10,25
COG1521,K,"Putative transcriptional regulator, homolog of Bvg accessory factor",1,1,0,2,4
COG1522,K,Transcriptional regulators,1,10,158,17,186
COG1523,G,"Type II secretory pathway, pullulanase PulA and related glycosidases",2,3,3,15,23
COG1524,R,Uncharacterized proteins of the AP superfamily,0,1,11,12,24
COG1525,L,Micrococcal nuclease (thermonuclease) homologs,0,0,16,0,16
COG1526,C,Uncharacterized protein required for formate dehydrogenase activity,0,1,18,1,20
COG1527,C,Archaeal/vacuolar-type H+-ATPase subunit C,0,0,0,3,3
COG1528,P,Ferritin-like protein,0,0,16,3,19
COG1529,C,"Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs",15,25,0,74,114
COG1530,J,Ribonucleases G and E,0,8,24,14,46
COG1531,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1532,R,Predicted RNA-binding protein,0,0,0,0,0
COG1533,L,DNA repair photolyase,0,1,2,4,7
COG1534,J,"Predicted RNA-binding protein containing KH domain, possibly ribosomal protein",0,0,0,0,0
COG1535,Q,Isochorismate hydrolase,1,0,0,0,1
COG1536,N,Flagellar motor switch protein,0,1,0,0,1
COG1537,R,Predicted RNA-binding proteins,0,0,0,4,4
COG1538,MU,Outer membrane protein,1,27,0,12,40
COG1539,H,Dihydroneopterin aldolase,0,2,1,2,5
COG1540,R,"Uncharacterized proteins, homologs of lactam utilization protein B",0,0,16,4,20
COG1541,H,Coenzyme F390 synthetase,0,6,16,1,23
COG1542,S,Uncharacterized conserved protein,0,0,0,0,0
COG1543,S,Uncharacterized conserved protein,0,0,1,4,5
COG1544,J,Ribosome-associated protein Y (PSrp-1),0,1,16,3,20
COG1545,R,Predicted nucleic-acid-binding protein containing a Zn-ribbon,0,0,0,3,3
COG1546,R,Uncharacterized protein (competence- and mitomycin-induced),0,4,18,6,28
COG1547,S,Uncharacterized conserved protein,0,0,0,0,0
COG1548,KG,Predicted transcriptional regulator/sugar kinase,0,1,0,0,1
COG1549,J,"Queuine tRNA-ribosyltransferases, contain PUA domain",0,0,0,0,0
COG1550,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1551,T,Carbon storage regulator (could also regulate swarming and quorum sensing),0,4,0,1,5
COG1552,J,Ribosomal protein L40E,0,0,0,0,0
COG1553,P,Uncharacterized conserved protein involved in intracellular sulfur reduction,0,0,0,0,0
COG1554,G,Trehalose and maltose hydrolases (possible phosphorylases),0,0,16,3,19
COG1555,L,DNA uptake protein and related DNA-binding proteins,0,1,15,1,17
COG1556,S,Uncharacterized conserved protein,0,1,15,1,17
COG1558,N,Flagellar basal body rod protein,0,1,0,0,1
COG1559,R,Predicted periplasmic solute-binding protein,0,2,31,3,36
COG1560,M,Lauroyl/myristoyl acyltransferase,1,3,0,17,21
COG1561,S,Uncharacterized stress-induced protein,3,2,2,5,12
COG1562,I,Phytoene/squalene synthetase,2,1,16,2,21
COG1563,P,Predicted subunit of the Multisubunit Na+/H+ antiporter,0,0,0,0,0
COG1564,H,Thiamine pyrophosphokinase,0,0,0,0,0
COG1565,S,Uncharacterized conserved protein,1,1,0,3,5
COG1566,V,Multidrug resistance efflux pump,3,28,1,30,62
COG1567,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1568,R,Predicted methyltransferases,0,0,0,0,0
COG1569,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,0,0
COG1570,L,"Exonuclease VII, large subunit",0,2,30,4,36
COG1571,R,Predicted DNA-binding protein containing a Zn-ribbon domain,0,0,0,2,2
COG1572,S,Uncharacterized conserved protein,0,0,0,0,0
COG1573,L,Uracil-DNA glycosylase,2,4,0,14,20
COG1574,R,Predicted metal-dependent hydrolase with the TIM-barrel fold,1,10,23,14,48
COG1575,H,"1,4-dihydroxy-2-naphthoate octaprenyltransferase",0,0,17,1,18
COG1576,S,Uncharacterized conserved protein,0,2,15,1,18
COG1577,I,Mevalonate kinase,0,0,0,3,3
COG1578,S,Uncharacterized conserved protein,0,0,0,0,0
COG1579,R,"Zn-ribbon protein, possibly nucleic acid-binding",0,0,0,2,2
COG1580,N,Flagellar basal body-associated protein,0,2,0,0,2
COG1581,K,Archaeal DNA-binding protein,0,0,1,2,3
COG1582,N,"Uncharacterized protein, possibly involved in motility",0,0,0,0,0
COG1583,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1584,S,Predicted membrane protein,0,1,0,2,3
COG1585,OU,Membrane protein implicated in regulation of membrane protease activity,0,0,5,0,5
COG1586,E,S-adenosylmethionine decarboxylase,0,3,0,0,3
COG1587,H,Uroporphyrinogen-III synthase,0,4,17,11,32
COG1588,J,RNase P/RNase MRP subunit p29,0,0,0,1,1
COG1589,M,Cell division septal protein,0,1,13,2,16
COG1590,S,Uncharacterized conserved protein,0,0,0,0,0
COG1591,L,Holliday junction resolvase - archaeal type,0,1,0,1,2
COG1592,C,Rubrerythrin,0,0,0,1,1
COG1593,G,"TRAP-type C4-dicarboxylate transport system, large permease component",0,2,41,12,55
COG1594,K,"DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS",0,0,0,1,1
COG1595,K,"DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog",4,40,111,56,211
COG1596,M,Periplasmic protein involved in polysaccharide export,0,4,0,14,18
COG1597,IR,Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase,1,6,24,19,50
COG1598,S,Uncharacterized conserved protein,0,3,0,0,3
COG1599,L,"Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins",0,0,0,1,1
COG1600,C,Uncharacterized Fe-S protein,0,3,0,7,10
COG1601,J,"Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain",0,0,0,2,2
COG1602,S,Uncharacterized conserved protein,0,0,0,3,3
COG1603,J,RNase P/RNase MRP subunit p30,0,0,0,0,0
COG1604,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1605,E,Chorismate mutase,0,1,16,0,17
COG1606,R,ATP-utilizing enzymes of the PP-loop superfamily,1,0,0,6,7
COG1607,I,Acyl-CoA hydrolase,0,3,25,4,32
COG1608,R,Predicted archaeal kinase,0,1,1,2,4
COG1609,K,Transcriptional regulators,0,9,156,10,175
COG1610,S,Uncharacterized conserved protein,0,0,27,3,30
COG1611,R,Predicted Rossmann fold nucleotide-binding protein,0,6,28,9,43
COG1612,O,Uncharacterized protein required for cytochrome oxidase assembly,0,1,19,7,27
COG1613,P,"ABC-type sulfate transport system, periplasmic component",0,5,0,0,5
COG1614,C,CO dehydrogenase/acetyl-CoA synthase beta subunit,0,0,0,0,0
COG1615,S,Uncharacterized conserved protein,0,7,14,9,30
COG1617,S,Uncharacterized conserved protein,0,0,0,0,0
COG1618,F,Predicted nucleotide kinase,0,0,0,1,1
COG1619,V,"Uncharacterized proteins, homologs of microcin C7 resistance protein MccF",2,1,27,3,33
COG1620,C,L-lactate permease,0,4,27,1,32
COG1621,G,Beta-fructosidases (levanase/invertase),0,0,28,1,29
COG1622,C,"Heme/copper-type cytochrome/quinol oxidases, subunit 2",2,11,15,12,40
COG1623,R,Predicted nucleic-acid-binding protein (contains the HHH domain),0,0,15,2,17
COG1624,S,Uncharacterized conserved protein,1,1,0,6,8
COG1625,C,"Fe-S oxidoreductase, related to NifB/MoaA family",0,0,0,0,0
COG1626,G,Neutral trehalase,0,2,0,1,3
COG1627,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1628,S,Uncharacterized conserved protein,0,0,0,1,1
COG1629,P,"Outer membrane receptor proteins, mostly Fe transport",0,3,0,2,5
COG1630,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1631,J,Ribosomal protein L44E,0,0,0,2,2
COG1632,J,Ribosomal protein L15E,0,0,0,2,2
COG1633,S,Uncharacterized conserved protein,0,0,0,1,1
COG1634,R,Uncharacterized Rossmann fold enzyme,0,0,0,2,2
COG1635,H,Flavoprotein involved in thiazole biosynthesis,0,0,2,3,5
COG1636,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1637,L,Predicted nuclease of the RecB family,0,0,12,0,12
COG1638,G,"TRAP-type C4-dicarboxylate transport system, periplasmic component",2,4,35,9,50
COG1639,T,Predicted signal transduction protein,0,4,0,0,4
COG1640,G,4-alpha-glucanotransferase,0,2,0,9,11
COG1641,S,Uncharacterized conserved protein,0,1,1,4,6
COG1643,L,HrpA-like helicases,0,4,41,2,47
COG1644,K,"DNA-directed RNA polymerase, subunit N (RpoN/RPB10)",0,0,0,1,1
COG1645,R,Uncharacterized Zn-finger containing protein,0,0,0,0,0
COG1646,R,"Predicted phosphate-binding enzymes, TIM-barrel fold",0,0,0,3,3
COG1647,R,Esterase/lipase,0,0,16,0,16
COG1648,H,Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain),0,1,0,2,3
COG1649,S,Uncharacterized protein conserved in bacteria,1,0,0,2,3
COG1650,S,Uncharacterized protein conserved in archaea,0,0,0,2,2
COG1651,O,Protein-disulfide isomerase,0,4,17,8,29
COG1652,S,Uncharacterized protein containing LysM domain,0,3,0,0,3
COG1653,G,"ABC-type sugar transport system, periplasmic component",1,3,31,11,46
COG1654,K,Biotin operon repressor,0,0,0,0,0
COG1655,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1656,S,Uncharacterized conserved protein,0,1,0,2,3
COG1657,I,Squalene cyclase,0,1,0,6,7
COG1658,L,Small primase-like proteins (Toprim domain),0,0,0,0,0
COG1659,S,"Uncharacterized protein, linocin/CFP29 homolog",0,0,0,0,0
COG1660,R,Predicted P-loop-containing kinase,0,3,19,3,25
COG1661,R,Predicted DNA-binding protein with PD1-like DNA-binding motif,1,0,0,0,1
COG1662,L,"Transposase and inactivated derivatives, IS1 family",0,0,1,6,7
COG1663,M,Tetraacyldisaccharide-1-P 4'-kinase,0,2,0,2,4
COG1664,M,Integral membrane protein CcmA involved in cell shape determination,0,1,0,6,7
COG1665,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1666,S,Uncharacterized protein conserved in bacteria,0,1,13,4,18
COG1667,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1668,CP,"ABC-type Na+ efflux pump, permease component",0,1,16,4,21
COG1669,R,Predicted nucleotidyltransferases,0,1,0,1,2
COG1670,J,"Acetyltransferases, including N-acetylases of ribosomal proteins",2,5,182,11,200
COG1671,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1672,R,Predicted ATPase (AAA+ superfamily),0,0,0,0,0
COG1673,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1674,D,DNA segregation ATPase FtsK/SpoIIIE and related proteins,1,7,61,14,83
COG1675,K,"Transcription initiation factor IIE, alpha subunit",0,0,0,2,2
COG1676,J,tRNA splicing endonuclease,0,0,0,4,4
COG1677,NU,Flagellar hook-basal body protein,0,0,0,0,0
COG1678,K,Putative transcriptional regulator,0,2,0,2,4
COG1679,S,Uncharacterized conserved protein,0,2,1,3,6
COG1680,V,Beta-lactamase class C and other penicillin binding proteins,6,9,50,36,101
COG1681,N,Archaeal flagellins,0,0,0,0,0
COG1682,GM,"ABC-type polysaccharide/polyol phosphate export systems, permease component",0,4,16,5,25
COG1683,S,Uncharacterized conserved protein,0,3,0,1,4
COG1684,NU,"Flagellar biosynthesis pathway, component FliR",0,1,0,0,1
COG1685,EH,Archaeal shikimate kinase,0,0,0,2,2
COG1686,M,D-alanyl-D-alanine carboxypeptidase,0,4,1,5,10
COG1687,E,Predicted branched-chain amino acid permeases (azaleucine resistance),0,0,0,0,0
COG1688,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1689,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1690,S,Uncharacterized conserved protein,0,3,4,8,15
COG1691,R,NCAIR mutase (PurE)-related proteins,0,0,2,2,4
COG1692,S,Uncharacterized protein conserved in bacteria,0,1,0,3,4
COG1693,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1694,R,Predicted pyrophosphatase,0,1,0,0,1
COG1695,K,Predicted transcriptional regulators,4,7,78,11,100
COG1696,M,Predicted membrane protein involved in D-alanine export,0,2,0,6,8
COG1697,L,"DNA topoisomerase VI, subunit A",0,0,0,2,2
COG1698,S,Uncharacterized protein conserved in archaea,0,0,0,1,1
COG1699,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1700,S,Uncharacterized conserved protein,0,0,0,0,0
COG1701,S,Uncharacterized protein conserved in archaea,0,0,1,2,3
COG1702,T,"Phosphate starvation-inducible protein PhoH, predicted ATPase",0,2,15,2,19
COG1703,E,Putative periplasmic protein kinase ArgK and related GTPases of G3E family,0,1,0,5,6
COG1704,S,Uncharacterized conserved protein,3,3,0,8,14
COG1705,NU,Muramidase (flagellum-specific),0,1,0,0,1
COG1706,N,Flagellar basal-body P-ring protein,0,2,0,0,2
COG1707,R,ACT domain-containing protein,0,0,0,0,0
COG1708,R,Predicted nucleotidyltransferases,0,0,0,0,0
COG1709,K,Predicted transcriptional regulator,0,0,0,0,0
COG1710,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1711,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1712,R,Predicted dinucleotide-utilizing enzyme,0,0,1,2,3
COG1713,H,Predicted HD superfamily hydrolase involved in NAD metabolism,0,0,0,0,0
COG1714,S,Predicted membrane protein/domain,0,0,0,0,0
COG1715,V,Restriction endonuclease,0,1,0,0,1
COG1716,T,FOG: FHA domain,0,3,41,4,48
COG1717,J,Ribosomal protein L32E,0,0,0,1,1
COG1718,TD,Serine/threonine protein kinase involved in cell cycle control,0,1,18,1,20
COG1719,R,Predicted hydrocarbon binding protein (contains V4R domain),0,0,0,0,0
COG1720,S,Uncharacterized conserved protein,0,0,0,1,1
COG1721,R,Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain),0,4,9,5,18
COG1722,L,Exonuclease VII small subunit,0,1,13,0,14
COG1723,S,Uncharacterized conserved protein,0,0,0,0,0
COG1724,N,Predicted periplasmic or secreted lipoprotein,0,1,0,0,1
COG1725,K,Predicted transcriptional regulators,1,0,60,2,63
COG1726,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA",0,0,0,0,0
COG1727,J,Ribosomal protein L18E,0,0,0,1,1
COG1728,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1729,S,Uncharacterized protein conserved in bacteria,0,3,0,4,7
COG1730,O,"Predicted prefoldin, molecular chaperone implicated in de novo protein folding",0,0,0,2,2
COG1731,H,Archaeal riboflavin synthase,0,0,0,0,0
COG1732,M,Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein),0,5,52,2,59
COG1733,K,Predicted transcriptional regulators,1,7,21,10,39
COG1734,T,DnaK suppressor protein,0,5,0,5,10
COG1735,R,Predicted metal-dependent hydrolase with the TIM-barrel fold,0,0,10,3,13
COG1736,J,Diphthamide synthase subunit DPH2,0,0,1,2,3
COG1737,K,Transcriptional regulators,0,7,0,1,8
COG1738,S,Uncharacterized conserved protein,0,0,13,1,14
COG1739,S,Uncharacterized conserved protein,0,0,20,0,20
COG1740,C,"Ni,Fe-hydrogenase I small subunit",0,0,0,1,1
COG1741,R,Pirin-related protein,0,8,11,7,26
COG1742,S,Uncharacterized conserved protein,0,1,0,2,3
COG1743,L,Adenine-specific DNA methylase containing a Zn-ribbon,0,0,0,0,0
COG1744,R,"Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein",0,3,19,7,29
COG1745,R,Predicted metal-binding protein,0,0,0,0,0
COG1746,J,tRNA nucleotidyltransferase (CCA-adding enzyme),0,0,0,3,3
COG1747,S,Uncharacterized N-terminal domain of the transcription elongation factor GreA,0,0,0,1,1
COG1748,E,Saccharopine dehydrogenase and related proteins,0,2,0,0,2
COG1749,N,Flagellar hook protein FlgE,0,1,0,0,1
COG1750,R,Archaeal serine proteases,0,0,0,0,0
COG1751,S,Uncharacterized conserved protein,0,0,0,0,0
COG1752,R,Predicted esterase of the alpha-beta hydrolase superfamily,0,4,0,7,11
COG1753,S,Uncharacterized conserved protein,0,0,0,0,0
COG1754,R,Uncharacterized C-terminal domain of topoisomerase IA,0,0,3,3,6
COG1755,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1756,S,Uncharacterized conserved protein,0,0,0,1,1
COG1757,C,Na+/H+ antiporter,0,0,0,0,0
COG1758,K,"DNA-directed RNA polymerase, subunit K/omega",0,1,13,2,16
COG1759,R,ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases),0,0,2,7,9
COG1760,E,L-serine deaminase,2,4,24,1,31
COG1761,K,"DNA-directed RNA polymerase, subunit L",0,0,0,0,0
COG1762,GT,Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type),0,1,8,5,14
COG1763,H,Molybdopterin-guanine dinucleotide biosynthesis protein,0,0,0,0,0
COG1764,O,"Predicted redox protein, regulator of disulfide bond formation",0,2,27,6,35
COG1765,O,"Predicted redox protein, regulator of disulfide bond formation",0,1,13,4,18
COG1766,NU,Flagellar biosynthesis/type III secretory pathway lipoprotein,0,2,0,1,3
COG1767,H,Triphosphoribosyl-dephospho-CoA synthetase,0,0,0,0,0
COG1768,R,Predicted phosphohydrolase,0,0,0,0,0
COG1769,L,Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily),0,0,0,0,0
COG1770,E,Protease II,0,14,36,6,56
COG1771,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1772,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1773,C,Rubredoxin,0,1,0,0,1
COG1774,S,Uncharacterized homolog of PSP1,0,0,0,0,0
COG1775,E,"Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB",0,0,0,0,0
COG1776,NT,"Chemotaxis protein CheC, inhibitor of MCP methylation",0,0,0,0,0
COG1777,K,Predicted transcriptional regulators,0,0,0,0,0
COG1778,R,Low specificity phosphatase (HAD superfamily),0,2,3,2,7
COG1779,R,C4-type Zn-finger protein,0,0,0,0,0
COG1780,F,Protein involved in ribonucleotide reduction,0,0,17,0,17
COG1781,F,"Aspartate carbamoyltransferase, regulatory subunit",0,0,0,2,2
COG1782,R,"Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain",0,1,7,10,18
COG1783,R,Phage terminase large subunit,0,3,4,1,8
COG1784,S,Predicted membrane protein,0,0,0,0,0
COG1785,P,Alkaline phosphatase,0,1,0,4,5
COG1786,S,Uncharacterized conserved protein,0,3,0,2,5
COG1787,V,Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes,0,1,0,0,1
COG1788,I,"Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit",0,2,44,16,62
COG1790,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1791,S,"Uncharacterized conserved protein, contains double-stranded beta-helix domain",0,1,0,0,1
COG1792,M,Cell shape-determining protein,0,1,0,1,2
COG1793,L,ATP-dependent DNA ligase,0,11,3,20,34
COG1794,M,Aspartate racemase,0,2,0,3,5
COG1795,S,Uncharacterized conserved protein,0,0,0,2,2
COG1796,L,DNA polymerase IV (family X),0,3,0,18,21
COG1797,H,"Cobyrinic acid a,c-diamide synthase",0,1,0,1,2
COG1798,J,Diphthamide biosynthesis methyltransferase,0,0,1,2,3
COG1799,S,Uncharacterized protein conserved in bacteria,0,0,15,0,15
COG1800,R,Predicted transglutaminase-like proteases,0,0,0,0,0
COG1801,S,Uncharacterized conserved protein,1,3,0,25,29
COG1802,K,Transcriptional regulators,0,9,157,4,170
COG1803,G,Methylglyoxal synthase,7,1,0,1,9
COG1804,C,Predicted acyl-CoA transferases/carnitine dehydratase,7,15,113,29,164
COG1805,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB",0,0,0,0,0
COG1806,S,Uncharacterized protein conserved in bacteria,0,1,0,2,3
COG1807,M,4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family,0,8,0,5,13
COG1808,S,Predicted membrane protein,0,0,0,0,0
COG1809,S,Uncharacterized conserved protein,8,0,0,2,10
COG1810,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1811,R,"Uncharacterized membrane protein, possible Na+ channel or pump",0,0,0,0,0
COG1812,E,Archaeal S-adenosylmethionine synthetase,0,0,0,0,0
COG1813,K,"Predicted transcription factor, homolog of eukaryotic MBF1",1,1,0,1,3
COG1814,S,Uncharacterized membrane protein,0,4,29,3,36
COG1815,N,Flagellar basal body protein,0,1,0,0,1
COG1816,F,Adenosine deaminase,0,2,29,2,33
COG1817,S,Uncharacterized protein conserved in archaea,0,2,0,3,5
COG1818,R,"Predicted RNA-binding protein, contains THUMP domain",0,0,0,2,2
COG1819,GC,"Glycosyl transferases, related to UDP-glucuronosyltransferase",0,5,17,6,28
COG1820,G,N-acetylglucosamine-6-phosphate deacetylase,2,4,14,15,35
COG1821,R,Predicted ATP-utilizing enzyme (ATP-grasp superfamily),0,0,0,0,0
COG1822,S,Predicted archaeal membrane protein,0,0,0,0,0
COG1823,R,Predicted Na+/dicarboxylate symporter,0,2,0,0,2
COG1824,P,"Permease, similar to cation transporters",0,0,0,0,0
COG1825,J,Ribosomal protein L25 (general stress protein Ctc),1,1,14,4,20
COG1826,U,Sec-independent protein secretion pathway components,1,1,41,8,51
COG1827,R,Predicted small molecule binding protein (contains 3H domain),0,0,0,0,0
COG1828,F,"Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component",0,2,15,2,19
COG1829,R,Predicted archaeal kinase (sugar kinase superfamily),0,0,0,1,1
COG1830,G,"DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes",0,0,3,8,11
COG1831,R,Predicted metal-dependent hydrolase (urease superfamily),0,0,0,0,0
COG1832,R,Predicted CoA-binding protein,0,0,31,5,36
COG1833,S,Uncharacterized conserved protein,0,0,0,0,0
COG1834,E,N-Dimethylarginine dimethylaminohydrolase,0,3,0,2,5
COG1835,I,Predicted acyltransferases,0,1,73,2,76
COG1836,S,Predicted membrane protein,0,0,0,0,0
COG1837,R,Predicted RNA-binding protein (contains KH domain),0,1,13,0,14
COG1838,C,"Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain",0,1,4,4,9
COG1839,S,Uncharacterized conserved protein,0,2,0,11,13
COG1840,P,"ABC-type Fe3+ transport system, periplasmic component",3,8,15,24,50
COG1841,J,Ribosomal protein L30/L7E,1,1,16,3,21
COG1842,KT,"Phage shock protein A (IM30), suppresses sigma54-dependent transcription",3,0,14,1,18
COG1843,N,Flagellar hook capping protein,0,1,0,0,1
COG1844,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1845,C,"Heme/copper-type cytochrome/quinol oxidase, subunit 3",3,8,16,5,32
COG1846,K,Transcriptional regulators,0,2,223,9,234
COG1847,R,Predicted RNA-binding protein,5,0,14,1,20
COG1848,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,0,0
COG1849,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1850,G,"Ribulose 1,5-bisphosphate carboxylase, large subunit",0,0,3,1,4
COG1851,S,Uncharacterized conserved protein,0,0,0,0,0
COG1852,S,Uncharacterized conserved protein,0,0,0,1,1
COG1853,R,"Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family",0,2,55,4,61
COG1854,T,LuxS protein involved in autoinducer AI2 synthesis,0,0,15,1,16
COG1855,R,ATPase (PilT family),0,0,2,5,7
COG1856,S,Uncharacterized homolog of biotin synthetase,0,0,0,0,0
COG1857,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG1858,P,Cytochrome c peroxidase,0,2,0,3,5
COG1859,J,RNA:NAD 2'-phosphotransferase,0,0,0,1,1
COG1860,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1861,M,"Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog",0,0,0,0,0
COG1862,U,Preprotein translocase subunit YajC,0,0,14,1,15
COG1863,P,"Multisubunit Na+/H+ antiporter, MnhE subunit",0,1,14,0,15
COG1864,F,"DNA/RNA endonuclease G, NUC1",0,3,1,2,6
COG1865,S,Uncharacterized conserved protein,0,0,0,0,0
COG1866,C,Phosphoenolpyruvate carboxykinase (ATP),0,6,5,15,26
COG1867,J,"N2,N2-dimethylguanosine tRNA methyltransferase",0,0,1,4,5
COG1868,N,Flagellar motor switch protein,0,2,0,2,4
COG1869,G,"ABC-type ribose transport system, auxiliary component",0,5,15,0,20
COG1871,NT,Chemotaxis protein; stimulates methylation of MCP proteins,0,0,0,0,0
COG1872,S,Uncharacterized conserved protein,0,2,0,0,2
COG1873,S,Uncharacterized conserved protein,0,0,0,2,2
COG1874,G,Beta-galactosidase,0,0,0,2,2
COG1875,T,Predicted ATPase related to phosphate starvation-inducible protein PhoH,0,3,19,0,22
COG1876,M,D-alanyl-D-alanine carboxypeptidase,0,0,29,1,30
COG1877,G,Trehalose-6-phosphatase,0,0,15,1,16
COG1878,R,Predicted metal-dependent hydrolase,4,2,14,8,28
COG1879,G,"ABC-type sugar transport system, periplasmic component",0,9,59,13,81
COG1880,C,CO dehydrogenase/acetyl-CoA synthase epsilon subunit,0,0,0,0,0
COG1881,R,Phospholipid-binding protein,1,1,0,3,5
COG1882,C,Pyruvate-formate lyase,1,0,0,4,5
COG1883,C,"Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit",0,0,0,0,0
COG1884,I,"Methylmalonyl-CoA mutase, N-terminal domain/subunit",1,4,0,8,13
COG1885,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1886,NU,Flagellar motor switch/type III secretory pathway protein,0,1,0,0,1
COG1887,M,Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC,0,0,53,1,54
COG1888,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1889,J,Fibrillarin-like rRNA methylase,0,0,2,2,4
COG1890,J,Ribosomal protein S3AE,0,0,0,2,2
COG1891,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1892,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG1893,H,Ketopantoate reductase,0,4,1,7,12
COG1894,C,"NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit",4,6,2,8,20
COG1895,S,"Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN",0,0,0,1,1
COG1896,R,Predicted hydrolases of HD superfamily,0,0,0,1,1
COG1897,E,Homoserine trans-succinylase,0,0,0,0,0
COG1898,M,"dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes",0,2,0,3,5
COG1899,O,Deoxyhypusine synthase,0,4,4,9,17
COG1900,S,Uncharacterized conserved protein,0,0,0,0,0
COG1901,S,Uncharacterized conserved protein,0,0,0,0,0
COG1902,C,"NADH:flavin oxidoreductases, Old Yellow Enzyme family",0,17,94,10,121
COG1903,H,Cobalamin biosynthesis protein CbiD,0,1,2,1,4
COG1904,G,Glucuronate isomerase,0,0,25,1,26
COG1905,C,NADH:ubiquinone oxidoreductase 24 kD subunit,1,3,0,4,8
COG1906,S,Uncharacterized conserved protein,0,0,0,0,0
COG1907,R,Predicted archaeal sugar kinases,0,0,0,0,0
COG1908,C,"Coenzyme F420-reducing hydrogenase, delta subunit",0,0,0,0,0
COG1909,S,Uncharacterized protein conserved in archaea,0,0,0,1,1
COG1910,P,Periplasmic molybdate-binding protein/domain,0,0,0,1,1
COG1911,J,Ribosomal protein L30E,0,0,0,2,2
COG1912,S,Uncharacterized conserved protein,0,1,0,0,1
COG1913,R,Predicted Zn-dependent proteases,0,0,0,2,2
COG1914,P,Mn2+ and Fe2+ transporters of the NRAMP family,1,4,33,11,49
COG1915,S,Uncharacterized conserved protein,1,0,1,8,10
COG1916,S,Uncharacterized homolog of PrgY (pheromone shutdown protein),0,0,0,0,0
COG1917,S,"Uncharacterized conserved protein, contains double-stranded beta-helix domain",6,5,30,8,49
COG1918,P,Fe2+ transport system protein A,0,0,0,0,0
COG1920,S,Uncharacterized conserved protein,0,0,0,1,1
COG1921,E,Selenocysteine synthase [seryl-tRNASer selenium transferase],1,3,0,5,9
COG1922,M,Teichoic acid biosynthesis proteins,0,2,9,0,11
COG1923,R,Uncharacterized host factor I protein,0,1,0,0,1
COG1924,I,Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain),0,0,0,0,0
COG1925,G,"Phosphotransferase system, HPr-related proteins",0,2,15,3,20
COG1926,R,Predicted phosphoribosyltransferases,1,1,0,7,9
COG1927,C,"Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin dehydrogenase",0,0,0,0,0
COG1928,O,Dolichyl-phosphate-mannose--protein O-mannosyl transferase,0,0,11,1,12
COG1929,G,Glycerate kinase,0,0,14,3,17
COG1930,P,"ABC-type cobalt transport system, periplasmic component",0,0,0,0,0
COG1931,S,Uncharacterized protein conserved in archaea,0,0,0,1,1
COG1932,HE,Phosphoserine aminotransferase,0,5,15,3,23
COG1933,L,"Archaeal DNA polymerase II, large subunit",0,0,0,1,1
COG1934,S,Uncharacterized protein conserved in bacteria,1,1,0,0,2
COG1935,S,Uncharacterized conserved protein,0,0,0,0,0
COG1936,F,Predicted nucleotide kinase (related to CMP and AMP kinases),0,0,0,2,2
COG1937,S,Uncharacterized protein conserved in bacteria,0,0,27,1,28
COG1938,R,Archaeal enzymes of ATP-grasp superfamily,0,0,0,1,1
COG1939,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1940,KG,Transcriptional regulator/sugar kinase,1,5,107,8,121
COG1941,C,"Coenzyme F420-reducing hydrogenase, gamma subunit",0,0,0,0,0
COG1942,R,"Uncharacterized protein, 4-oxalocrotonate tautomerase homolog",0,0,0,0,0
COG1943,L,Transposase and inactivated derivatives,1,0,3,9,13
COG1944,S,Uncharacterized conserved protein,0,2,0,5,7
COG1945,S,Uncharacterized conserved protein,0,0,0,2,2
COG1946,I,Acyl-CoA thioesterase,0,2,50,0,52
COG1947,I,4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase,0,3,14,1,18
COG1948,L,ERCC4-type nuclease,0,0,1,2,3
COG1949,A,Oligoribonuclease (3'->5' exoribonuclease),0,1,11,0,12
COG1950,S,Predicted membrane protein,0,0,11,2,13
COG1951,C,"Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain",1,1,18,3,23
COG1952,U,Preprotein translocase subunit SecB,0,2,0,0,2
COG1953,FH,Cytosine/uracil/thiamine/allantoin permeases,0,7,13,4,24
COG1954,K,Glycerol-3-phosphate responsive antiterminator (mRNA-binding),0,0,0,0,0
COG1955,NU,Archaeal flagella assembly protein J,0,0,0,0,0
COG1956,T,GAF domain-containing protein,0,1,0,5,6
COG1957,F,Inosine-uridine nucleoside N-ribohydrolase,0,1,26,14,41
COG1958,K,Small nuclear ribonucleoprotein (snRNP) homolog,0,0,2,2,4
COG1959,K,Predicted transcriptional regulator,0,2,13,0,15
COG1960,I,Acyl-CoA dehydrogenases,13,48,295,71,427
COG1961,L,"Site-specific recombinases, DNA invertase Pin homologs",0,1,37,18,56
COG1962,H,"Tetrahydromethanopterin S-methyltransferase, subunit H",0,0,0,0,0
COG1963,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1964,R,Predicted Fe-S oxidoreductases,0,6,3,7,16
COG1965,P,"Protein implicated in iron transport, frataxin homolog",0,2,0,1,3
COG1966,T,"Carbon starvation protein, predicted membrane protein",0,6,16,19,41
COG1967,S,Predicted membrane protein,0,0,0,0,0
COG1968,V,Uncharacterized bacitracin resistance protein,0,4,18,11,33
COG1969,C,"Ni,Fe-hydrogenase I cytochrome b subunit",0,0,0,0,0
COG1970,M,Large-conductance mechanosensitive channel,1,2,13,6,22
COG1971,S,Predicted membrane protein,0,0,0,0,0
COG1972,F,Nucleoside permease,0,0,0,4,4
COG1973,O,Hydrogenase maturation factor,0,0,0,0,0
COG1974,KT,SOS-response transcriptional repressors (RecA-mediated autopeptidases),0,6,23,7,36
COG1975,O,"Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family",0,2,15,1,18
COG1976,J,Translation initiation factor 6 (eIF-6),0,0,2,2,4
COG1977,H,"Molybdopterin converting factor, small subunit",1,1,2,4,8
COG1978,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG1979,C,"Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family",0,0,0,0,0
COG1980,G,"Archaeal fructose 1,6-bisphosphatase",2,0,3,3,8
COG1981,S,Predicted membrane protein,0,1,0,0,1
COG1982,E,Arginine/lysine/ornithine decarboxylases,1,8,24,7,40
COG1983,KT,Putative stress-responsive transcriptional regulator,0,0,21,2,23
COG1984,E,Allophanate hydrolase subunit 2,0,2,17,3,22
COG1985,H,"Pyrimidine reductase, riboflavin biosynthesis",0,1,27,7,35
COG1986,S,Uncharacterized conserved protein,0,0,0,0,0
COG1987,NU,"Flagellar biosynthesis pathway, component FliQ",0,1,0,0,1
COG1988,R,Predicted membrane-bound metal-dependent hydrolases,0,0,0,0,0
COG1989,NOU,"Type II secretory pathway, prepilin signal peptidase PulO and related peptidases",0,1,0,3,4
COG1990,S,Uncharacterized conserved protein,0,0,16,1,17
COG1991,S,Uncharacterized conserved protein,0,0,0,0,0
COG1992,S,Uncharacterized conserved protein,0,0,1,2,3
COG1993,S,Uncharacterized conserved protein,0,1,0,0,1
COG1994,R,Zn-dependent proteases,1,0,14,4,19
COG1995,H,Pyridoxal phosphate biosynthesis protein,0,2,0,3,5
COG1996,K,"DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger)",0,0,0,1,1
COG1997,J,Ribosomal protein L37AE/L43A,0,0,0,0,0
COG1998,J,Ribosomal protein S27AE,0,0,0,1,1
COG1999,R,"Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems",0,2,0,13,15
COG2000,R,Predicted Fe-S protein,0,0,0,0,0
COG2001,S,Uncharacterized protein conserved in bacteria,3,2,16,3,24
COG2002,K,Regulators of stationary/sporulation gene expression,0,0,0,0,0
COG2003,L,DNA repair proteins,1,1,0,5,7
COG2004,J,Ribosomal protein S24E,0,0,0,0,0
COG2005,R,N-terminal domain of molybdenum-binding protein,0,0,0,1,1
COG2006,S,Uncharacterized conserved protein,0,0,0,1,1
COG2007,J,Ribosomal protein S8E,0,0,0,2,2
COG2008,E,Threonine aldolase,0,3,23,1,27
COG2009,C,"Succinate dehydrogenase/fumarate reductase, cytochrome b subunit",0,1,15,1,17
COG2010,C,"Cytochrome c, mono- and diheme variants",0,3,14,0,17
COG2011,P,"ABC-type metal ion transport system, permease component",0,4,26,2,32
COG2012,K,"DNA-directed RNA polymerase, subunit H, RpoH/RPB5",0,0,0,1,1
COG2013,S,Uncharacterized conserved protein,0,0,0,4,4
COG2014,S,Uncharacterized conserved protein,0,0,0,0,0
COG2015,Q,Alkyl sulfatase and related hydrolases,0,0,0,0,0
COG2016,J,Predicted RNA-binding protein (contains PUA domain),0,0,0,2,2
COG2017,G,Galactose mutarotase and related enzymes,1,4,13,8,26
COG2018,R,Uncharacterized distant relative of homeotic protein bithoraxoid,0,0,0,0,0
COG2019,F,Archaeal adenylate kinase,0,0,0,2,2
COG2020,O,Putative protein-S-isoprenylcysteine methyltransferase,1,5,2,6,14
COG2021,E,Homoserine acetyltransferase,0,1,17,4,22
COG2022,H,Uncharacterized enzyme of thiazole biosynthesis,0,2,17,7,26
COG2023,J,RNase P subunit RPR2,0,0,0,1,1
COG2024,J,Phenylalanyl-tRNA synthetase alpha subunit (archaeal type),0,0,0,0,0
COG2025,C,"Electron transfer flavoprotein, alpha subunit",0,5,16,7,28
COG2026,JD,Cytotoxic translational repressor of toxin-antitoxin stability system,0,0,0,0,0
COG2027,M,D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4),0,2,15,6,23
COG2028,S,Uncharacterized conserved protein,0,0,0,0,0
COG2029,S,Uncharacterized conserved protein,0,0,0,0,0
COG2030,I,Acyl dehydratase,1,5,86,4,96
COG2031,I,Short chain fatty acids transporter,0,1,0,0,1
COG2032,P,Cu/Zn superoxide dismutase,2,0,0,0,2
COG2033,C,Desulfoferrodoxin,0,0,0,0,0
COG2034,S,Predicted membrane protein,0,0,0,0,0
COG2035,S,Predicted membrane protein,0,0,0,0,0
COG2036,B,Histones H3 and H4,0,0,0,1,1
COG2037,C,Formylmethanofuran:tetrahydromethanopterin formyltransferase,0,0,0,0,0
COG2038,H,NaMN:DMB phosphoribosyltransferase,0,1,0,4,5
COG2039,O,Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase),0,0,14,0,14
COG2040,E,Homocysteine/selenocysteine methylase (S-methylmethionine-dependent),0,1,26,1,28
COG2041,R,Sulfite oxidase and related enzymes,2,4,17,13,36
COG2042,S,Uncharacterized conserved protein,0,0,0,1,1
COG2043,S,Uncharacterized protein conserved in archaea,0,0,0,1,1
COG2044,R,Predicted peroxiredoxins,0,0,0,0,0
COG2045,HR,Phosphosulfolactate phosphohydrolase and related enzymes,1,0,0,1,2
COG2046,P,ATP sulfurylase (sulfate adenylyltransferase),0,6,3,8,17
COG2047,R,Uncharacterized protein (ATP-grasp superfamily),0,0,0,5,5
COG2048,C,"Heterodisulfide reductase, subunit B",0,0,0,4,4
COG2049,E,Allophanate hydrolase subunit 1,0,2,3,1,6
COG2050,Q,"Uncharacterized protein, possibly involved in aromatic compounds catabolism",0,4,77,11,92
COG2051,J,Ribosomal protein S27E,0,0,0,0,0
COG2052,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2053,J,Ribosomal protein S28E/S33,0,0,1,1,2
COG2054,R,"Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases",0,0,0,0,0
COG2055,C,Malate/L-lactate dehydrogenases,0,4,33,5,42
COG2056,R,Predicted permease,0,2,0,0,2
COG2057,I,"Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit",0,5,34,3,42
COG2058,J,Ribosomal protein L12E/L44/L45/RPP1/RPP2,0,0,0,2,2
COG2059,P,Chromate transport protein ChrA,0,2,12,3,17
COG2060,P,"K+-transporting ATPase, A chain",0,4,0,9,13
COG2061,E,"ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase",0,0,0,0,0
COG2062,T,Phosphohistidine phosphatase SixA,0,1,15,8,24
COG2063,N,Flagellar basal body L-ring protein,0,1,0,1,2
COG2064,NU,Flp pilus assembly protein TadC,0,2,0,0,2
COG2065,F,Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase,4,1,17,5,27
COG2066,E,Glutaminase,0,1,24,10,35
COG2067,I,Long-chain fatty acid transport protein,1,2,0,0,3
COG2068,R,Uncharacterized MobA-related protein,0,1,0,0,1
COG2069,C,CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein),0,0,0,0,0
COG2070,R,Dioxygenases related to 2-nitropropane dioxygenase,0,3,16,1,20
COG2071,R,Predicted glutamine amidotransferases,0,1,0,2,3
COG2072,P,Predicted flavoprotein involved in K+ transport,0,3,93,8,104
COG2073,H,Cobalamin biosynthesis protein CbiG,0,0,0,3,3
COG2074,G,2-phosphoglycerate kinase,0,0,0,0,0
COG2075,J,Ribosomal protein L24E,0,0,0,0,0
COG2076,P,Membrane transporters of cations and cationic drugs,0,3,12,0,15
COG2077,O,Peroxiredoxin,0,2,16,1,19
COG2078,S,Uncharacterized conserved protein,0,0,0,3,3
COG2079,R,Uncharacterized protein involved in propionate catabolism,3,5,44,15,67
COG2080,C,"Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs",5,8,0,17,30
COG2081,R,Predicted flavoproteins,0,3,0,3,6
COG2082,H,Precorrin isomerase,0,0,0,1,1
COG2083,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG2084,I,3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases,0,5,39,25,69
COG2085,R,Predicted dinucleotide-binding enzymes,0,5,28,16,49
COG2086,C,"Electron transfer flavoprotein, beta subunit",0,3,14,3,20
COG2087,H,Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase,0,2,0,0,2
COG2088,M,"Uncharacterized protein, involved in the regulation of septum location",0,0,0,0,0
COG2089,M,Sialic acid synthase,1,2,15,11,29
COG2090,S,Uncharacterized protein conserved in archaea,0,0,0,2,2
COG2091,H,Phosphopantetheinyl transferase,0,1,15,0,16
COG2092,J,Translation elongation factor EF-1beta,0,0,0,2,2
COG2093,K,"DNA-directed RNA polymerase, subunit E''",0,0,0,0,0
COG2094,L,3-methyladenine DNA glycosylase,0,1,16,2,19
COG2095,U,Multiple antibiotic transporter,0,2,0,5,7
COG2096,S,Uncharacterized conserved protein,2,2,0,5,9
COG2097,J,Ribosomal protein L31E,0,0,0,1,1
COG2098,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG2099,H,Precorrin-6x reductase,0,0,0,0,0
COG2100,R,Predicted Fe-S oxidoreductase,0,0,0,0,0
COG2101,K,"TATA-box binding protein (TBP), component of TFIID and TFIIIB",0,0,0,1,1
COG2102,R,Predicted ATPases of PP-loop superfamily,0,0,0,2,2
COG2103,R,Predicted sugar phosphate isomerase,0,0,0,3,3
COG2104,H,Sulfur transfer protein involved in thiamine biosynthesis,0,1,14,2,17
COG2105,S,Uncharacterized conserved protein,0,0,0,0,0
COG2106,S,Uncharacterized conserved protein,0,0,0,1,1
COG2107,R,Predicted periplasmic solute-binding protein,0,1,2,6,9
COG2108,R,Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme,0,0,0,0,0
COG2109,H,ATP:corrinoid adenosyltransferase,0,4,0,3,7
COG2110,R,Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1,0,2,5,2,9
COG2111,P,"Multisubunit Na+/H+ antiporter, MnhB subunit",0,1,6,0,7
COG2112,T,Predicted Ser/Thr protein kinase,0,0,0,2,2
COG2113,E,"ABC-type proline/glycine betaine transport systems, periplasmic components",0,17,0,0,17
COG2114,T,"Adenylate cyclase, family 3 (some proteins contain HAMP domain)",3,3,17,54,77
COG2115,G,Xylose isomerase,1,1,16,1,19
COG2116,P,Formate/nitrite family of transporters,0,1,0,1,2
COG2117,J,"Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain",0,0,0,0,0
COG2118,R,DNA-binding protein,0,0,0,1,1
COG2119,S,Predicted membrane protein,0,1,0,0,1
COG2120,S,"Uncharacterized proteins, LmbE homologs",0,1,27,17,45
COG2121,S,Uncharacterized protein conserved in bacteria,0,3,0,3,6
COG2122,S,Uncharacterized conserved protein,0,0,0,0,0
COG2123,J,RNase PH-related exoribonuclease,0,0,0,3,3
COG2124,Q,Cytochrome P450,1,3,53,12,69
COG2125,J,Ribosomal protein S6E (S10),0,0,0,2,2
COG2126,J,Ribosomal protein L37E,0,0,0,0,0
COG2127,S,Uncharacterized conserved protein,0,1,16,3,20
COG2128,S,Uncharacterized conserved protein,0,4,47,2,53
COG2129,R,"Predicted phosphoesterases, related to the Icc protein",0,0,0,1,1
COG2130,R,Putative NADP-dependent oxidoreductases,0,6,8,2,16
COG2131,F,Deoxycytidylate deaminase,0,3,1,1,5
COG2132,Q,Putative multicopper oxidases,0,8,6,21,35
COG2133,G,Glucose/sorbosone dehydrogenases,1,10,13,33,57
COG2134,I,CDP-diacylglycerol pyrophosphatase,0,0,0,0,0
COG2135,S,Uncharacterized conserved protein,0,2,17,2,21
COG2136,JA,"Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain",0,0,0,0,0
COG2137,R,Uncharacterized protein conserved in bacteria,0,1,15,0,16
COG2138,S,Uncharacterized conserved protein,0,1,15,2,18
COG2139,J,Ribosomal protein L21E,0,0,0,1,1
COG2140,GR,Thermophilic glucose-6-phosphate isomerase and related metalloenzymes,0,3,0,8,11
COG2141,C,"Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases",8,17,208,46,279
COG2142,C,"Succinate dehydrogenase, hydrophobic anchor subunit",0,0,15,0,15
COG2143,O,Thioredoxin-related protein,0,0,0,1,1
COG2144,R,Selenophosphate synthetase-related proteins,0,0,0,0,0
COG2145,H,"Hydroxyethylthiazole kinase, sugar kinase family",0,0,14,0,14
COG2146,PR,Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases,0,4,30,12,46
COG2147,J,Ribosomal protein L19E,0,0,2,1,3
COG2148,M,Sugar transferases involved in lipopolysaccharide synthesis,1,1,16,11,29
COG2149,S,Predicted membrane protein,0,0,11,1,12
COG2150,R,"Predicted regulator of amino acid metabolism, contains ACT domain",0,0,0,0,0
COG2151,R,Predicted metal-sulfur cluster biosynthetic enzyme,0,1,28,11,40
COG2152,G,Predicted glycosylase,0,0,1,2,3
COG2153,R,Predicted acyltransferase,0,2,0,1,3
COG2154,H,Pterin-4a-carbinolamine dehydratase,1,2,15,7,25
COG2155,S,Uncharacterized conserved protein,0,0,0,0,0
COG2156,P,"K+-transporting ATPase, c chain",0,2,0,11,13
COG2157,J,Ribosomal protein L20A (L18A),0,0,0,0,0
COG2158,R,Uncharacterized protein containing a Zn-finger-like domain,0,0,0,0,0
COG2159,R,Predicted metal-dependent hydrolase of the TIM-barrel fold,7,6,30,21,64
COG2160,G,L-arabinose isomerase,0,0,27,2,29
COG2161,D,Antitoxin of toxin-antitoxin stability system,0,1,0,0,1
COG2162,Q,Arylamine N-acetyltransferase,0,2,0,1,3
COG2163,J,Ribosomal protein L14E/L6E/L27E,0,0,0,0,0
COG2164,S,Uncharacterized conserved protein,0,0,0,1,1
COG2165,NU,"Type II secretory pathway, pseudopilin PulG",0,1,0,1,2
COG2166,R,SufE protein probably involved in Fe-S center assembly,0,1,12,1,14
COG2167,J,Ribosomal protein L39E,0,0,0,0,0
COG2168,P,Uncharacterized conserved protein involved in oxidation of intracellular sulfur,0,1,0,0,1
COG2169,F,Adenosine deaminase,0,2,0,17,19
COG2170,S,Uncharacterized conserved protein,0,6,48,11,65
COG2171,E,Tetrahydrodipicolinate N-succinyltransferase,0,0,14,2,16
COG2172,T,Anti-sigma regulatory factor (Ser/Thr protein kinase),0,5,0,2,7
COG2173,M,D-alanyl-D-alanine dipeptidase,0,1,0,2,3
COG2174,J,Ribosomal protein L34E,0,0,0,0,0
COG2175,Q,Probable taurine catabolism dioxygenase,2,5,0,2,9
COG2176,L,"DNA polymerase III, alpha subunit (gram-positive type)",0,1,0,1,2
COG2177,D,Cell division protein,0,2,10,0,12
COG2178,J,Predicted RNA-binding protein of the translin family,0,0,0,2,2
COG2179,R,Predicted hydrolase of the HAD superfamily,0,0,0,0,0
COG2180,C,Nitrate reductase delta subunit,0,1,0,0,1
COG2181,C,Nitrate reductase gamma subunit,1,1,0,0,2
COG2182,G,Maltose-binding periplasmic proteins/domains,0,0,16,5,21
COG2183,K,Transcriptional accessory protein,0,2,16,3,21
COG2184,D,Protein involved in cell division,0,0,0,0,0
COG2185,I,"Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)",0,1,0,3,4
COG2186,K,Transcriptional regulators,0,9,141,8,158
COG2187,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2188,K,Transcriptional regulators,2,8,21,6,37
COG2189,L,Adenine specific DNA methylase Mod,0,1,39,2,42
COG2190,G,Phosphotransferase system IIA components,0,2,0,0,2
COG2191,C,Formylmethanofuran dehydrogenase subunit E,0,2,0,0,2
COG2192,O,"Predicted carbamoyl transferase, NodU family",0,18,0,15,33
COG2193,P,Bacterioferritin (cytochrome b1),0,4,0,1,5
COG2194,R,"Predicted membrane-associated, metal-dependent hydrolase",0,5,0,3,8
COG2195,E,Di- and tripeptidases,0,1,0,1,2
COG2197,TK,Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain,2,25,282,57,366
COG2198,T,FOG: HPt domain,0,0,0,1,1
COG2199,T,FOG: GGDEF domain,0,34,31,27,92
COG2200,T,FOG: EAL domain,4,37,16,8,65
COG2201,NT,Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain,0,3,0,3,6
COG2202,T,FOG: PAS/PAC domain,1,4,0,3,8
COG2203,T,FOG: GAF domain,0,8,0,14,22
COG2204,T,"Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains",20,77,14,134,245
COG2205,T,Osmosensitive K+ channel histidine kinase,13,22,2,38,75
COG2206,T,HD-GYP domain,1,0,1,10,12
COG2207,K,AraC-type DNA-binding domain-containing proteins,5,24,101,8,138
COG2208,TK,"Serine phosphatase RsbU, regulator of sigma subunit",1,9,1,36,47
COG2209,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE",0,0,0,0,0
COG2210,S,Uncharacterized conserved protein,0,0,0,0,0
COG2211,G,Na+/melibiose symporter and related transporters,0,0,27,5,32
COG2212,P,"Multisubunit Na+/H+ antiporter, MnhF subunit",0,1,0,0,1
COG2213,G,"Phosphotransferase system, mannitol-specific IIBC component",0,0,0,0,0
COG2214,O,DnaJ-class molecular chaperone,0,0,0,0,0
COG2215,R,"ABC-type uncharacterized transport system, permease component",0,0,0,0,0
COG2216,P,"High-affinity K+ transport system, ATPase chain B",0,3,0,8,11
COG2217,P,Cation transport ATPase,11,18,20,25,74
COG2218,C,Formylmethanofuran dehydrogenase subunit C,0,1,0,0,1
COG2219,L,"Eukaryotic-type DNA primase, large subunit",0,0,0,2,2
COG2220,R,Predicted Zn-dependent hydrolases of the beta-lactamase fold,0,4,16,9,29
COG2221,C,"Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits",0,0,0,0,0
COG2222,M,Predicted phosphosugar isomerases,0,5,0,0,5
COG2223,P,Nitrate/nitrite transporter,0,5,44,1,50
COG2224,C,Isocitrate lyase,0,2,23,8,33
COG2225,C,Malate synthase,0,10,28,3,41
COG2226,H,Methylase involved in ubiquinone/menaquinone biosynthesis,8,21,105,56,190
COG2227,H,"2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase",0,8,61,7,76
COG2229,R,Predicted GTPase,0,0,0,0,0
COG2230,M,Cyclopropane fatty acid synthase and related methyltransferases,1,1,0,2,4
COG2231,L,Uncharacterized protein related to Endonuclease III,0,0,0,0,0
COG2232,R,Predicted ATP-dependent carboligase related to biotin carboxylase,0,0,0,1,1
COG2233,F,Xanthine/uracil permeases,0,9,43,1,53
COG2234,R,Predicted aminopeptidases,1,3,0,12,16
COG2235,E,Arginine deiminase,0,1,0,0,1
COG2236,R,Predicted phosphoribosyltransferases,0,0,0,0,0
COG2237,S,Predicted membrane protein,0,0,0,4,4
COG2238,J,Ribosomal protein S19E (S16A),0,0,0,2,2
COG2239,P,Mg/Co/Ni transporter MgtE (contains CBS domain),1,4,34,17,56
COG2240,H,Pyridoxal/pyridoxine/pyridoxamine kinase,0,1,22,0,23
COG2241,H,Precorrin-6B methylase 1,1,0,0,2,3
COG2242,H,Precorrin-6B methylase 2,0,0,0,2,2
COG2243,H,Precorrin-2 methylase,0,4,0,2,6
COG2244,R,Membrane protein involved in the export of O-antigen and teichoic acid,0,0,12,3,15
COG2245,S,Predicted membrane protein,0,0,0,0,0
COG2246,S,Predicted membrane protein,0,0,29,1,30
COG2247,M,Putative cell wall-binding domain,0,0,14,1,15
COG2248,R,Predicted hydrolase (metallo-beta-lactamase superfamily),0,0,0,0,0
COG2249,R,Putative NADPH-quinone reductase (modulator of drug activity B),0,1,0,1,2
COG2250,S,"Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN",0,0,0,1,1
COG2251,R,Predicted nuclease (RecB family),0,0,15,0,15
COG2252,R,Permeases,0,3,7,2,12
COG2253,S,Uncharacterized conserved protein,0,0,0,0,0
COG2254,L,"Predicted HD superfamily hydrolase, possibly a nuclease",0,0,0,0,0
COG2255,L,"Holliday junction resolvasome, helicase subunit",2,7,18,4,31
COG2256,L,ATPase related to the helicase subunit of the Holliday junction resolvase,0,4,37,1,42
COG2257,S,Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB,0,1,0,0,1
COG2258,S,Uncharacterized protein conserved in bacteria,0,0,1,5,6
COG2259,S,Predicted membrane protein,0,1,28,2,31
COG2260,J,Predicted Zn-ribbon RNA-binding protein,0,0,0,0,0
COG2261,S,Predicted membrane protein,0,0,7,2,9
COG2262,R,GTPases,2,4,20,12,38
COG2263,J,Predicted RNA methylase,0,0,0,0,0
COG2264,J,Ribosomal protein L11 methylase,0,3,0,12,15
COG2265,J,SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase,0,6,47,9,62
COG2266,H,GTP:adenosylcobinamide-phosphate guanylyltransferase,0,0,0,2,2
COG2267,I,Lysophospholipase,1,4,30,6,41
COG2268,S,Uncharacterized protein conserved in bacteria,1,0,0,2,3
COG2269,J,"Truncated, possibly inactive, lysyl-tRNA synthetase (class II)",0,0,0,3,3
COG2270,R,Permeases of the major facilitator superfamily,0,2,20,4,26
COG2271,G,Sugar phosphate permease,4,16,211,9,240
COG2272,I,Carboxylesterase type B,0,1,13,3,17
COG2273,G,Beta-glucanase/Beta-glucan synthetase,0,1,0,1,2
COG2274,V,"ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain",2,37,9,11,59
COG2301,G,Citrate lyase beta subunit,1,3,67,13,84
COG2302,S,"Uncharacterized conserved protein, contains S4-like domain",0,0,0,0,0
COG2303,E,Choline dehydrogenase and related flavoproteins,3,16,25,32,76
COG2304,R,Uncharacterized protein containing a von Willebrand factor type A (vWA) domain,0,1,0,0,1
COG2306,S,Uncharacterized conserved protein,0,0,0,0,0
COG2307,S,Uncharacterized protein conserved in bacteria,0,2,2,3,7
COG2308,S,Uncharacterized conserved protein,0,6,0,3,9
COG2309,E,Leucyl aminopeptidase (aminopeptidase T),1,0,0,5,6
COG2310,T,"Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1",0,1,0,0,1
COG2311,S,Predicted membrane protein,0,0,0,0,0
COG2312,R,Erythromycin esterase homolog,0,2,0,3,5
COG2313,Q,Uncharacterized enzyme involved in pigment biosynthesis,0,1,0,0,1
COG2314,S,Predicted membrane protein,0,1,0,0,1
COG2315,S,Uncharacterized protein conserved in bacteria,0,0,15,2,17
COG2316,R,Predicted hydrolase (HD superfamily),0,0,0,2,2
COG2317,E,Zn-dependent carboxypeptidase,0,0,4,4,8
COG2318,S,Uncharacterized protein conserved in bacteria,0,2,0,3,5
COG2319,R,FOG: WD40 repeat,0,2,0,12,14
COG2320,S,Uncharacterized conserved protein,0,1,14,0,15
COG2321,R,Predicted metalloprotease,4,3,0,1,8
COG2322,S,Predicted membrane protein,0,1,0,1,2
COG2323,S,Predicted membrane protein,0,0,0,1,1
COG2324,S,Predicted membrane protein,0,0,0,0,0
COG2326,S,Uncharacterized conserved protein,0,5,25,7,37
COG2327,S,Uncharacterized conserved protein,0,0,0,0,0
COG2329,R,Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides,0,3,21,1,25
COG2331,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG2332,O,Cytochrome c-type biogenesis protein CcmE,0,1,0,1,2
COG2333,R,Predicted hydrolase (metallo-beta-lactamase superfamily),0,5,22,7,34
COG2334,R,Putative homoserine kinase type II (protein kinase fold),0,5,0,0,5
COG2335,M,Secreted and surface protein containing fasciclin-like repeats,0,0,15,1,16
COG2336,T,Growth regulator,0,1,0,0,1
COG2337,T,Growth inhibitor,0,1,0,1,2
COG2339,S,Predicted membrane protein,0,0,0,1,1
COG2340,S,Uncharacterized protein with SCP/PR1 domains,0,2,0,4,6
COG2342,G,"Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase",0,0,0,0,0
COG2343,S,Uncharacterized protein conserved in bacteria,1,1,0,0,2
COG2344,R,AT-rich DNA-binding protein,0,0,13,0,13
COG2345,K,Predicted transcriptional regulator,0,1,20,3,24
COG2346,R,Truncated hemoglobins,0,0,13,0,13
COG2348,V,Uncharacterized protein involved in methicillin resistance,0,0,18,4,22
COG2350,S,Uncharacterized protein conserved in bacteria,0,0,12,0,12
COG2351,R,Transthyretin-like protein,0,0,14,1,15
COG2352,C,Phosphoenolpyruvate carboxylase,0,2,0,5,7
COG2353,S,Uncharacterized conserved protein,2,3,16,3,24
COG2354,S,Uncharacterized protein conserved in bacteria,0,1,15,6,22
COG2355,E,"Zn-dependent dipeptidase, microsomal dipeptidase homolog",1,4,0,21,26
COG2356,L,Endonuclease I,0,2,0,0,2
COG2357,S,Uncharacterized protein conserved in bacteria,0,1,22,1,24
COG2358,R,"TRAP-type uncharacterized transport system, periplasmic component",0,0,16,4,20
COG2359,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2360,O,Leu/Phe-tRNA-protein transferase,1,1,0,2,4
COG2361,S,Uncharacterized conserved protein,0,1,0,0,1
COG2362,E,D-aminopeptidase,0,0,0,0,0
COG2363,S,Uncharacterized small membrane protein,0,0,0,1,1
COG2364,S,Predicted membrane protein,0,0,14,0,14
COG2365,T,Protein tyrosine/serine phosphatase,0,1,20,0,21
COG2366,R,Protein related to penicillin acylase,0,7,0,11,18
COG2367,V,Beta-lactamase class A,0,1,0,3,4
COG2368,Q,Aromatic ring hydroxylase,0,0,16,12,28
COG2369,S,"Uncharacterized protein, homolog of phage Mu protein gp30",0,1,0,0,1
COG2370,O,Hydrogenase/urease accessory protein,0,2,0,0,2
COG2371,O,Urease accessory protein UreE,0,1,16,2,19
COG2372,R,"Uncharacterized protein, homolog of Cu resistance protein CopC",0,2,16,3,21
COG2373,R,Large extracellular alpha-helical protein,0,9,0,19,28
COG2374,R,Predicted extracellular nuclease,0,0,15,2,17
COG2375,P,Siderophore-interacting protein,0,2,45,5,52
COG2376,G,Dihydroxyacetone kinase,0,0,0,1,1
COG2377,O,Predicted molecular chaperone distantly related to HSP70-fold metalloproteases,0,2,0,1,3
COG2378,K,Predicted transcriptional regulator,0,1,30,3,34
COG2379,G,Putative glycerate kinase,0,2,3,4,9
COG2380,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2382,P,Enterochelin esterase and related enzymes,0,0,0,4,4
COG2383,S,Uncharacterized conserved protein,0,0,0,1,1
COG2384,R,Predicted SAM-dependent methyltransferase,0,0,0,0,0
COG2385,D,Sporulation protein and related proteins,0,0,0,1,1
COG2386,O,"ABC-type transport system involved in cytochrome c biogenesis, permease component",0,2,0,0,2
COG2388,R,Predicted acetyltransferase,0,1,22,1,24
COG2389,R,Uncharacterized metal-binding protein,0,0,0,0,0
COG2390,K,"Transcriptional regulator, contains sigma factor-related N-terminal domain",0,0,18,1,19
COG2391,R,Predicted transporter component,0,1,0,0,1
COG2401,R,ABC-type ATPase fused to a predicted acetyltransferase domain,0,0,0,0,0
COG2402,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,0,0
COG2403,R,Predicted GTPase,0,0,0,0,0
COG2404,R,Predicted phosphohydrolase (DHH superfamily),0,0,0,3,3
COG2405,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,1,1
COG2406,R,Protein distantly related to bacterial ferritins,0,0,0,2,2
COG2407,G,L-fucose isomerase and related proteins,0,0,0,0,0
COG2409,R,Predicted drug exporters of the RND superfamily,0,0,99,6,105
COG2410,S,Uncharacterized conserved protein,0,0,0,0,0
COG2411,S,Uncharacterized conserved protein,0,0,0,0,0
COG2412,S,Uncharacterized conserved protein,0,0,0,1,1
COG2413,R,Predicted nucleotidyltransferase,0,0,0,0,0
COG2414,C,Aldehyde:ferredoxin oxidoreductase,0,0,0,6,6
COG2419,S,Uncharacterized conserved protein,0,0,0,0,0
COG2421,C,Predicted acetamidase/formamidase,1,0,0,3,4
COG2423,E,"Predicted ornithine cyclodeaminase, mu-crystallin homolog",1,1,17,16,35
COG2425,R,Uncharacterized protein containing a von Willebrand factor type A (vWA) domain,0,1,0,0,1
COG2426,S,Predicted membrane protein,0,0,0,0,0
COG2427,S,Uncharacterized conserved protein,0,0,0,0,0
COG2428,S,Uncharacterized conserved protein,0,0,0,0,0
COG2429,S,Uncharacterized conserved protein,0,0,1,3,4
COG2430,S,Uncharacterized conserved protein,0,0,0,0,0
COG2431,S,Predicted membrane protein,0,0,0,0,0
COG2433,S,Uncharacterized conserved protein,0,0,0,0,0
COG2440,C,Ferredoxin-like protein,0,0,0,1,1
COG2441,C,Predicted butyrate kinase,0,0,0,0,0
COG2442,S,Uncharacterized conserved protein,0,3,0,2,5
COG2443,U,Preprotein translocase subunit Sss1,0,0,0,1,1
COG2445,S,Uncharacterized conserved protein,0,0,0,0,0
COG2450,S,Uncharacterized conserved protein,0,0,0,1,1
COG2451,J,Ribosomal protein L35AE/L33A,0,0,0,0,0
COG2452,L,Predicted site-specific integrase-resolvase,0,0,0,0,0
COG2453,T,Predicted protein-tyrosine phosphatase,0,1,0,3,4
COG2454,S,Uncharacterized conserved protein,0,0,0,0,0
COG2456,S,Uncharacterized conserved protein,0,0,0,0,0
COG2457,S,Uncharacterized conserved protein,0,0,0,0,0
COG2461,S,Uncharacterized conserved protein,0,0,0,0,0
COG2469,S,Uncharacterized conserved protein,0,0,0,0,0
COG2501,S,Uncharacterized conserved protein,0,0,16,0,16
COG2502,E,Asparagine synthetase A,0,0,0,1,1
COG2503,R,Predicted secreted acid phosphatase,0,0,0,0,0
COG2508,TQ,Regulator of polyketide synthase expression,0,0,29,1,30
COG2509,R,Uncharacterized FAD-dependent dehydrogenases,2,2,0,0,4
COG2510,S,Predicted membrane protein,0,0,0,0,0
COG2511,J,Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain),2,1,0,3,6
COG2512,S,Uncharacterized membrane-associated protein/domain,0,0,0,2,2
COG2513,G,PEP phosphonomutase and related enzymes,0,12,36,10,58
COG2514,R,Predicted ring-cleavage extradiol dioxygenase,0,0,19,6,25
COG2515,E,1-aminocyclopropane-1-carboxylate deaminase,0,4,0,2,6
COG2516,R,Biotin synthase-related enzyme,0,0,0,0,0
COG2517,R,Predicted RNA-binding protein containing a C-terminal EMAP domain,0,0,0,0,0
COG2518,O,Protein-L-isoaspartate carboxylmethyltransferase,1,10,0,2,13
COG2519,J,tRNA(1-methyladenosine) methyltransferase and related methyltransferases,0,0,14,3,17
COG2520,R,Predicted methyltransferase,0,0,2,16,18
COG2521,R,Predicted archaeal methyltransferase,0,0,0,1,1
COG2522,R,Predicted transcriptional regulator,0,0,0,1,1
COG2524,K,"Predicted transcriptional regulator, contains C-terminal CBS domains",0,1,1,2,4
COG2602,V,Beta-lactamase class D,0,0,0,0,0
COG2603,R,Predicted ATPase,0,2,0,0,2
COG2604,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2605,R,Predicted kinase related to galactokinase and mevalonate kinase,1,1,0,3,5
COG2606,S,Uncharacterized conserved protein,0,2,31,5,38
COG2607,R,Predicted ATPase (AAA+ superfamily),0,2,0,0,2
COG2608,P,Copper chaperone,0,2,14,0,16
COG2609,C,"Pyruvate dehydrogenase complex, dehydrogenase (E1) component",0,3,38,6,47
COG2610,GE,H+/gluconate symporter and related permeases,0,5,34,0,39
COG2703,P,Hemerythrin,0,0,0,0,0
COG2704,R,Anaerobic C4-dicarboxylate transporter,0,0,0,3,3
COG2706,G,3-carboxymuconate cyclase,3,3,0,4,10
COG2707,S,Predicted membrane protein,0,0,0,0,0
COG2710,C,"Nitrogenase molybdenum-iron protein, alpha and beta chains",0,0,0,0,0
COG2715,R,"Uncharacterized membrane protein, required for spore maturation in B.subtilis.",0,1,0,1,2
COG2716,E,Glycine cleavage system regulatory protein,0,1,0,1,2
COG2717,S,Predicted membrane protein,0,0,0,2,2
COG2718,S,Uncharacterized conserved protein,0,2,0,0,2
COG2719,S,Uncharacterized conserved protein,0,3,0,3,6
COG2720,V,Uncharacterized vancomycin resistance protein,0,1,14,1,16
COG2721,G,Altronate dehydratase,0,4,0,1,5
COG2723,G,Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase,0,1,26,3,30
COG2730,G,Endoglucanase,0,1,0,1,2
COG2731,G,"Beta-galactosidase, beta subunit",0,0,0,0,0
COG2732,K,"Barstar, RNAse (barnase) inhibitor",0,0,0,0,0
COG2733,S,Predicted membrane protein,0,1,16,2,19
COG2738,R,Predicted Zn-dependent protease,0,0,0,3,3
COG2739,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2740,K,Predicted nucleic-acid-binding protein implicated in transcription termination,0,0,13,0,13
COG2746,V,Aminoglycoside N3'-acetyltransferase,0,1,0,0,1
COG2747,KNU,Negative regulator of flagellin synthesis (anti-sigma28 factor),0,1,0,0,1
COG2755,E,Lysophospholipase L1 and related esterases,0,3,49,2,54
COG2759,F,Formyltetrahydrofolate synthetase,1,0,21,7,29
COG2761,Q,Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis,0,2,15,4,21
COG2764,S,Uncharacterized protein conserved in bacteria,2,5,72,9,88
COG2766,T,Putative Ser protein kinase,0,6,0,3,9
COG2768,R,Uncharacterized Fe-S center protein,0,0,0,1,1
COG2770,T,FOG: HAMP domain,1,3,0,2,6
COG2771,K,DNA-binding HTH domain-containing proteins,0,0,0,0,0
COG2801,L,Transposase and inactivated derivatives,2,3,4,17,26
COG2802,R,"Uncharacterized protein, similar to the N-terminal domain of Lon protease",1,1,0,1,3
COG2804,NU,"Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB",3,13,0,41,57
COG2805,NU,"Tfp pilus assembly protein, pilus retraction ATPase PilT",4,12,1,16,33
COG2807,P,Cyanate permease,0,4,59,3,66
COG2808,K,Transcriptional regulator,0,3,0,0,3
COG2810,V,Predicted type IV restriction endonuclease,0,0,0,0,0
COG2811,C,Archaeal/vacuolar-type H+-ATPase subunit H,0,0,0,0,0
COG2812,L,"DNA polymerase III, gamma/tau subunits",2,5,29,19,55
COG2813,J,16S RNA G1207 methylase RsmC,0,2,29,0,31
COG2814,G,Arabinose efflux permease,0,24,489,24,537
COG2815,S,Uncharacterized protein conserved in bacteria,0,0,11,0,11
COG2816,L,"NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding",1,1,33,3,38
COG2818,L,3-methyladenine DNA glycosylase,0,4,25,12,41
COG2819,R,Predicted hydrolase of the alpha/beta superfamily,0,1,0,3,4
COG2820,F,Uridine phosphorylase,0,0,0,0,0
COG2821,M,Membrane-bound lytic murein transglycosylase,0,1,0,0,1
COG2822,P,Predicted periplasmic lipoprotein involved in iron transport,0,0,16,0,16
COG2823,R,Predicted periplasmic or secreted lipoprotein,0,7,0,3,10
COG2824,P,Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism,0,1,15,1,17
COG2825,M,Outer membrane protein,0,3,0,1,4
COG2826,L,"Transposase and inactivated derivatives, IS30 family",1,3,1,7,12
COG2827,L,Predicted endonuclease containing a URI domain,0,1,0,1,2
COG2828,S,Uncharacterized protein conserved in bacteria,0,2,29,2,33
COG2829,M,Outer membrane phospholipase A,0,0,0,0,0
COG2830,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2831,U,Hemolysin activation/secretion protein,0,5,0,0,5
COG2832,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2833,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2834,M,Outer membrane lipoprotein-sorting protein,0,1,0,0,1
COG2835,S,Uncharacterized conserved protein,0,1,0,2,3
COG2836,S,Uncharacterized conserved protein,0,1,0,0,1
COG2837,P,Predicted iron-dependent peroxidase,0,1,48,6,55
COG2838,C,Monomeric isocitrate dehydrogenase,1,8,15,3,27
COG2839,S,Uncharacterized protein conserved in bacteria,0,0,15,1,16
COG2840,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2841,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2842,R,"Uncharacterized ATPase, putative transposase",0,0,0,0,0
COG2843,M,Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation),0,0,15,1,16
COG2844,O,UTP:GlnB (protein PII) uridylyltransferase,6,4,1,9,20
COG2845,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2846,D,Regulator of cell morphogenesis and NO signaling,0,1,0,1,2
COG2847,S,Uncharacterized protein conserved in bacteria,0,0,15,0,15
COG2848,S,Uncharacterized conserved protein,0,2,0,2,4
COG2849,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2850,S,Uncharacterized conserved protein,0,3,0,0,3
COG2851,C,H+/citrate symporter,1,2,24,2,29
COG2852,S,Uncharacterized protein conserved in bacteria,0,0,0,3,3
COG2853,M,Surface lipoprotein,0,3,0,1,4
COG2854,Q,"ABC-type transport system involved in resistance to organic solvents, auxiliary component",0,2,0,3,5
COG2855,S,Predicted membrane protein,1,2,15,2,20
COG2856,E,Predicted Zn peptidase,0,2,9,0,11
COG2857,C,Cytochrome c1,0,1,0,2,3
COG2859,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2860,S,Predicted membrane protein,0,0,14,7,21
COG2861,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2862,S,Predicted membrane protein,0,1,0,0,1
COG2863,C,Cytochrome c553,1,3,0,1,5
COG2864,C,Cytochrome b subunit of formate dehydrogenase,0,1,0,0,1
COG2865,K,Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen,0,2,0,0,2
COG2866,E,Predicted carboxypeptidase,0,2,0,0,2
COG2867,I,Oligoketide cyclase/lipid transport protein,0,1,0,0,1
COG2868,J,Predicted ribosomal protein,0,0,0,0,0
COG2869,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC",0,0,0,0,0
COG2870,M,"ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase",0,5,0,9,14
COG2871,C,"Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF",0,0,0,1,1
COG2872,R,Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain,0,0,14,2,16
COG2873,E,O-acetylhomoserine sulfhydrylase,0,0,54,9,63
COG2874,NU,Predicted ATPases involved in biogenesis of archaeal flagella,0,0,0,0,0
COG2875,H,Precorrin-4 methylase,2,1,0,4,7
COG2876,E,3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase,0,1,0,6,7
COG2877,M,3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase,0,3,0,1,4
COG2878,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfB",0,1,0,0,1
COG2879,S,Uncharacterized small protein,0,2,0,0,2
COG2880,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG2881,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG2882,NUO,Flagellar biosynthesis chaperone,0,1,0,0,1
COG2884,D,Predicted ATPase involved in cell division,0,2,8,1,11
COG2885,M,Outer membrane protein and related peptidoglycan-associated (lipo)proteins,0,11,0,11,22
COG2886,S,Uncharacterized small protein,0,0,0,0,0
COG2887,L,RecB family exonuclease,0,0,1,0,1
COG2888,J,Predicted Zn-ribbon RNA-binding protein with a function in translation,0,0,0,0,0
COG2890,J,Methylase of polypeptide chain release factors,0,4,44,8,56
COG2891,M,Cell shape-determining protein,0,2,0,0,2
COG2892,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG2893,G,"Phosphotransferase system, mannose/fructose-specific component IIA",0,1,0,1,2
COG2894,D,Septum formation inhibitor-activating ATPase,0,1,0,0,1
COG2895,P,GTPases - Sulfate adenylate transferase subunit 1,0,1,15,4,20
COG2896,H,Molybdenum cofactor biosynthesis enzyme,0,5,15,12,32
COG2897,P,Rhodanese-related sulfurtransferase,2,4,39,13,58
COG2898,S,Uncharacterized conserved protein,1,4,22,4,31
COG2899,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2900,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2901,KL,"Factor for inversion stimulation Fis, transcriptional activator",0,1,2,2,5
COG2902,E,NAD-specific glutamate dehydrogenase,0,5,23,5,33
COG2904,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2905,T,Predicted signal-transduction protein containing cAMP-binding and CBS domains,1,6,4,26,37
COG2906,P,Bacterioferritin-associated ferredoxin,0,0,0,0,0
COG2907,R,Predicted NAD/FAD-binding protein,0,1,0,0,1
COG2908,S,Uncharacterized protein conserved in bacteria,0,2,0,5,7
COG2909,K,ATP-dependent transcriptional regulator,0,5,1,19,25
COG2910,R,Putative NADH-flavin reductase,0,2,25,0,27
COG2911,S,Uncharacterized protein conserved in bacteria,0,3,0,2,5
COG2912,S,Uncharacterized conserved protein,0,0,0,6,6
COG2913,J,Small protein A (tmRNA-binding),0,1,0,1,2
COG2914,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2915,R,Uncharacterized protein involved in purine metabolism,0,2,0,0,2
COG2916,R,DNA-binding protein H-NS,0,0,0,0,0
COG2917,D,Intracellular septation protein A,0,1,0,0,1
COG2918,H,Gamma-glutamylcysteine synthetase,0,1,0,0,1
COG2919,D,Septum formation initiator,0,1,13,0,14
COG2920,P,"Dissimilatory sulfite reductase (desulfoviridin), gamma subunit",0,1,0,0,1
COG2921,S,Uncharacterized conserved protein,0,0,0,0,0
COG2922,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG2923,P,Uncharacterized protein involved in the oxidation of intracellular sulfur,0,1,0,0,1
COG2924,CO,Fe-S cluster protector protein,0,1,0,1,2
COG2925,L,Exonuclease I,0,2,0,0,2
COG2926,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2927,L,"DNA polymerase III, chi subunit",0,1,0,0,1
COG2928,S,Uncharacterized conserved protein,0,0,0,2,2
COG2929,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2930,S,Uncharacterized conserved protein,0,2,0,6,8
COG2931,Q,RTX toxins and related Ca2+-binding proteins,0,0,0,1,1
COG2932,K,Predicted transcriptional regulator,0,5,0,0,5
COG2933,R,Predicted SAM-dependent methyltransferase,0,2,0,0,2
COG2935,O,Putative arginyl-tRNA:protein arginylyltransferase,0,1,0,1,2
COG2936,R,Predicted acyl esterases,1,11,44,8,64
COG2937,I,Glycerol-3-phosphate O-acyltransferase,0,6,0,1,7
COG2938,S,Uncharacterized conserved protein,0,1,0,0,1
COG2939,E,Carboxypeptidase C (cathepsin A),0,2,0,2,4
COG2940,R,Proteins containing SET domain,0,1,0,3,4
COG2941,H,Ubiquinone biosynthesis protein COQ7,0,1,0,0,1
COG2942,G,N-acyl-D-glucosamine 2-epimerase,0,3,0,0,3
COG2943,M,Membrane glycosyltransferase,0,2,0,0,2
COG2944,K,Predicted transcriptional regulator,0,1,0,0,1
COG2945,R,Predicted hydrolase of the alpha/beta superfamily,1,2,0,1,4
COG2946,L,Putative phage replication protein RstA,0,0,0,0,0
COG2947,S,Uncharacterized conserved protein,0,2,0,4,6
COG2948,U,"Type IV secretory pathway, VirB10 components",0,0,0,0,0
COG2949,S,Uncharacterized membrane protein,0,0,0,0,0
COG2951,M,Membrane-bound lytic murein transglycosylase B,0,4,0,1,5
COG2952,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2954,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG2956,G,Predicted N-acetylglucosaminyl transferase,0,2,0,2,4
COG2957,E,Peptidylarginine deiminase and related enzymes,0,5,0,2,7
COG2958,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2959,H,Uncharacterized enzyme of heme biosynthesis,0,1,0,0,1
COG2960,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2961,R,Protein involved in catabolism of external DNA,0,8,0,0,8
COG2962,R,Predicted permeases,0,3,37,2,42
COG2963,L,Transposase and inactivated derivatives,0,1,0,1,2
COG2964,S,Uncharacterized protein conserved in bacteria,0,2,0,2,4
COG2965,L,Primosomal replication protein N,0,0,0,0,0
COG2966,S,Uncharacterized conserved protein,0,0,17,1,18
COG2967,P,Uncharacterized protein affecting Mg2+/Co2+ transport,0,1,0,1,2
COG2968,S,Uncharacterized conserved protein,0,0,2,3,5
COG2969,R,Stringent starvation protein B,0,1,0,0,1
COG2971,G,Predicted N-acetylglucosamine kinase,0,0,16,6,22
COG2972,T,Predicted signal transduction protein with a C-terminal ATPase domain,0,0,9,1,10
COG2973,K,Trp operon repressor,0,0,0,0,0
COG2974,L,DNA recombination-dependent growth factor C,0,1,0,0,1
COG2975,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2976,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2977,Q,Phosphopantetheinyl transferase component of siderophore synthetase,0,0,0,0,0
COG2978,H,Putative p-aminobenzoyl-glutamate transporter,0,0,16,1,17
COG2979,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG2980,M,Rare lipoprotein B,0,1,0,0,1
COG2981,E,Uncharacterized protein involved in cysteine biosynthesis,0,2,0,0,2
COG2982,M,Uncharacterized protein involved in outer membrane biogenesis,0,8,0,1,9
COG2983,S,Uncharacterized conserved protein,0,1,0,0,1
COG2984,R,"ABC-type uncharacterized transport system, periplasmic component",1,5,19,15,40
COG2985,R,Predicted permease,0,0,0,7,7
COG2986,E,Histidine ammonia-lyase,0,15,16,12,43
COG2987,E,Urocanate hydratase,0,5,33,6,44
COG2988,E,Succinylglutamate desuccinylase,0,3,0,0,3
COG2989,S,Uncharacterized protein conserved in bacteria,0,1,0,2,3
COG2990,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG2991,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG2992,R,Uncharacterized FlgJ-related protein,0,0,0,0,0
COG2993,C,"Cbb3-type cytochrome oxidase, cytochrome c subunit",0,4,0,5,9
COG2994,O,ACP:hemolysin acyltransferase (hemolysin-activating protein),0,0,0,0,0
COG2995,S,Uncharacterized paraquat-inducible protein A,0,5,0,1,6
COG2996,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG2998,H,"ABC-type tungstate transport system, permease component",0,0,0,1,1
COG2999,O,Glutaredoxin 2,0,0,0,0,0
COG3000,I,Sterol desaturase,0,1,0,3,4
COG3001,G,Fructosamine-3-kinase,0,0,0,0,0
COG3002,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3004,P,Na+/H+ antiporter,0,2,32,3,37
COG3005,C,"Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit",0,0,0,1,1
COG3006,D,Uncharacterized protein involved in chromosome partitioning,0,0,0,0,0
COG3007,S,Uncharacterized paraquat-inducible protein B,0,0,0,0,0
COG3008,R,Paraquat-inducible protein B,0,8,0,0,8
COG3009,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3010,G,Putative N-acetylmannosamine-6-phosphate epimerase,0,0,18,1,19
COG3011,S,Uncharacterized protein conserved in bacteria,0,1,0,4,5
COG3012,S,Uncharacterized protein conserved in bacteria,0,1,16,0,17
COG3013,S,Uncharacterized conserved protein,0,0,0,0,0
COG3014,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3015,MP,Uncharacterized lipoprotein NlpE involved in copper resistance,0,0,0,0,0
COG3016,S,Uncharacterized iron-regulated protein,0,1,0,1,2
COG3017,M,Outer membrane lipoprotein involved in outer membrane biogenesis,0,1,0,0,1
COG3018,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3019,R,Predicted metal-binding protein,1,1,0,0,2
COG3021,S,Uncharacterized protein conserved in bacteria,0,0,29,0,29
COG3022,S,Uncharacterized protein conserved in bacteria,0,1,11,0,12
COG3023,V,Negative regulator of beta-lactamase expression,0,7,0,3,10
COG3024,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3025,S,Uncharacterized conserved protein,0,2,0,0,2
COG3026,T,Negative regulator of sigma E activity,0,2,0,0,2
COG3027,S,Uncharacterized protein conserved in bacteria,1,2,0,0,3
COG3028,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3029,C,Fumarate reductase subunit C,0,0,0,0,0
COG3030,R,Protein affecting phage T7 exclusion by the F plasmid,0,1,0,0,1
COG3031,U,"Type II secretory pathway, component PulC",0,0,0,0,0
COG3033,E,Tryptophanase,0,0,0,2,2
COG3034,S,Uncharacterized protein conserved in bacteria,0,2,0,1,3
COG3036,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3037,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3038,C,Cytochrome B561,0,5,0,1,6
COG3039,L,"Transposase and inactivated derivatives, IS5 family",2,0,0,0,2
COG3040,M,Bacterial lipocalin,0,1,0,0,1
COG3041,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3042,R,Putative hemolysin,0,0,0,0,0
COG3043,C,Nitrate reductase cytochrome c-type subunit,0,0,0,0,0
COG3044,R,Predicted ATPase of the ABC class,0,0,0,0,0
COG3045,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3046,R,Uncharacterized protein related to deoxyribodipyrimidine photolyase,0,0,0,0,0
COG3047,M,Outer membrane protein W,0,1,0,0,1
COG3048,E,D-serine dehydratase,0,0,0,0,0
COG3049,M,Penicillin V acylase and related amidases,0,0,0,0,0
COG3050,L,"DNA polymerase III, psi subunit",0,0,0,0,0
COG3051,C,"Citrate lyase, alpha subunit",0,0,0,0,0
COG3052,C,"Citrate lyase, gamma subunit",0,0,0,0,0
COG3053,C,Citrate lyase synthetase,0,0,0,0,0
COG3054,R,Predicted transcriptional regulator,0,0,0,0,0
COG3055,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3056,M,Uncharacterized lipoprotein,0,0,0,0,0
COG3057,L,Negative regulator of replication initiationR,0,0,0,0,0
COG3058,O,Uncharacterized protein involved in formate dehydrogenase formation,0,1,0,1,2
COG3059,S,Predicted membrane protein,0,0,0,1,1
COG3060,KE,Transcriptional regulator of met regulon,4,0,0,0,4
COG3061,M,Cell envelope opacity-associated protein A,0,1,0,0,1
COG3062,P,Uncharacterized protein involved in formation of periplasmic nitrate reductase,0,0,0,0,0
COG3063,NU,Tfp pilus assembly protein PilF,1,10,0,15,26
COG3064,M,Membrane protein involved in colicin uptake,0,0,13,0,13
COG3065,M,Starvation-inducible outer membrane lipoprotein,0,0,0,0,0
COG3066,L,DNA mismatch repair protein,0,0,0,0,0
COG3067,P,Na+/H+ antiporter,0,2,0,0,2
COG3068,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3069,C,C4-dicarboxylate transporter,0,0,0,0,0
COG3070,K,Regulator of competence-specific genes,0,1,0,0,1
COG3071,H,Uncharacterized enzyme of heme biosynthesis,0,3,0,0,3
COG3072,F,Adenylate cyclase,0,4,0,0,4
COG3073,T,Negative regulator of sigma E activity,0,1,0,0,1
COG3074,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3075,E,Anaerobic glycerol-3-phosphate dehydrogenase,0,0,0,0,0
COG3076,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3077,L,DNA-damage-inducible protein J,0,0,0,0,0
COG3078,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3079,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3080,C,Fumarate reductase subunit D,0,0,0,0,0
COG3081,R,Nucleoid-associated protein,0,1,0,0,1
COG3082,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3083,R,Predicted hydrolase of alkaline phosphatase superfamily,0,0,0,1,1
COG3084,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3085,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3086,T,Positive regulator of sigma E activity,0,0,0,0,0
COG3087,D,Cell division protein,0,0,0,0,0
COG3088,O,Uncharacterized protein involved in biosynthesis of c-type cytochromes,0,4,0,1,5
COG3089,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3090,G,"TRAP-type C4-dicarboxylate transport system, small permease component",0,1,27,3,31
COG3091,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3092,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3093,R,Plasmid maintenance system antidote protein,0,1,14,0,15
COG3094,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3095,D,Uncharacterized protein involved in chromosome partitioning,0,0,0,0,0
COG3096,D,Uncharacterized protein involved in chromosome partitioning,0,0,0,0,0
COG3097,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3098,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3099,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3100,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3101,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3102,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3103,T,SH3 domain protein,0,0,13,0,13
COG3104,E,Dipeptide/tripeptide permease,1,1,21,11,34
COG3105,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3106,R,Predicted ATPase,0,0,0,0,0
COG3107,R,Putative lipoprotein,1,3,0,0,4
COG3108,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3109,T,Activator of osmoprotectant transporter ProP,0,0,0,0,0
COG3110,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3111,S,Uncharacterized conserved protein,0,0,0,0,0
COG3112,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3113,R,Predicted NTP binding protein (contains STAS domain),0,1,0,0,1
COG3114,U,Heme exporter protein D,0,1,0,0,1
COG3115,D,Cell division protein,0,2,0,0,2
COG3116,D,Cell division protein,0,1,0,0,1
COG3117,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3118,O,Thioredoxin domain-containing protein,0,0,41,17,58
COG3119,P,Arylsulfatase A and related enzymes,10,6,0,27,43
COG3120,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3121,NU,"P pilus assembly protein, chaperone PapD",0,0,0,0,0
COG3122,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3123,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3124,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3125,C,"Heme/copper-type cytochrome/quinol oxidase, subunit 4",0,1,0,0,1
COG3126,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3127,Q,"Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component",2,4,16,4,26
COG3128,S,Uncharacterized iron-regulated protein,0,1,0,0,1
COG3129,R,Predicted SAM-dependent methyltransferase,0,2,0,0,2
COG3130,J,Ribosome modulation factor,0,1,0,0,1
COG3131,P,Periplasmic glucans biosynthesis protein,0,7,0,0,7
COG3132,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3133,M,Outer membrane lipoprotein,0,2,0,0,2
COG3134,S,Predicted outer membrane lipoprotein,0,2,0,0,2
COG3135,Q,Uncharacterized protein involved in benzoate metabolism,0,2,33,1,36
COG3136,R,Uncharacterized membrane protein required for alginate biosynthesis,0,1,0,0,1
COG3137,M,Putative salt-induced outer membrane protein,0,0,0,0,0
COG3138,E,Arginine/ornithine N-succinyltransferase beta subunit,0,5,0,0,5
COG3139,S,Uncharacterized protein conserved in bacteria,3,0,0,0,3
COG3140,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3141,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3142,P,Uncharacterized protein involved in copper resistance,0,0,0,0,0
COG3143,NT,Chemotaxis protein,0,0,0,0,0
COG3144,N,Flagellar hook-length control protein,0,0,0,0,0
COG3145,L,Alkylated DNA repair protein,0,2,16,1,19
COG3146,S,Uncharacterized protein conserved in bacteria,1,2,0,4,7
COG3147,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3148,S,Uncharacterized conserved protein,0,2,0,0,2
COG3149,U,"Type II secretory pathway, component PulM",0,0,0,0,0
COG3150,R,Predicted esterase,0,2,0,0,2
COG3151,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3152,S,Predicted membrane protein,0,1,0,0,1
COG3153,R,Predicted acetyltransferase,1,0,17,3,21
COG3154,I,Putative lipid carrier protein,0,1,0,0,1
COG3155,Q,Uncharacterized protein involved in an early stage of isoprenoid biosynthesis,0,3,0,0,3
COG3156,U,"Type II secretory pathway, component PulK",0,0,0,0,0
COG3157,S,Hemolysin-coregulated protein (uncharacterized),0,4,0,0,4
COG3158,P,K+ transporter,0,3,0,7,10
COG3159,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3160,K,Regulator of sigma D,0,1,0,0,1
COG3161,H,4-hydroxybenzoate synthetase (chorismate lyase),0,1,0,0,1
COG3162,S,Predicted membrane protein,0,1,16,0,17
COG3164,S,Predicted membrane protein,0,5,0,0,5
COG3165,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3166,NU,Tfp pilus assembly protein PilN,0,1,0,1,2
COG3167,NU,Tfp pilus assembly protein PilO,2,1,0,0,3
COG3168,NU,Tfp pilus assembly protein PilP,0,0,0,0,0
COG3169,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3170,NU,Tfp pilus assembly protein FimV,0,2,0,0,2
COG3171,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3172,H,Predicted ATPase/kinase involved in NAD metabolism,0,1,0,0,1
COG3173,R,Predicted aminoglycoside phosphotransferase,0,1,68,2,71
COG3174,S,Predicted membrane protein,0,0,0,0,0
COG3175,O,Cytochrome oxidase assembly factor,0,2,0,0,2
COG3176,R,Putative hemolysin,0,0,0,0,0
COG3177,S,Uncharacterized conserved protein,0,2,13,12,27
COG3178,R,Predicted phosphotransferase related to Ser/Thr protein kinases,0,1,0,1,2
COG3179,R,Predicted chitinase,1,4,0,0,5
COG3180,R,Putative ammonia monooxygenase,0,1,0,0,1
COG3181,S,Uncharacterized protein conserved in bacteria,4,5,55,22,86
COG3182,S,Uncharacterized iron-regulated membrane protein,0,4,0,0,4
COG3183,V,Predicted restriction endonuclease,0,0,0,0,0
COG3184,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3185,ER,4-hydroxyphenylpyruvate dioxygenase and related hemolysins,1,4,0,8,13
COG3186,E,Phenylalanine-4-hydroxylase,0,1,0,1,2
COG3187,O,Heat shock protein,0,0,16,0,16
COG3188,NU,"P pilus assembly protein, porin PapC",0,0,0,0,0
COG3189,S,Uncharacterized conserved protein,0,1,16,3,20
COG3190,N,Flagellar biogenesis protein,0,1,0,1,2
COG3191,EQ,L-aminopeptidase/D-esterase,0,2,0,5,7
COG3192,E,Ethanolamine utilization protein,0,0,0,0,0
COG3193,R,"Uncharacterized protein, possibly involved in utilization of glycolate and propanediol",0,4,0,0,4
COG3194,F,Ureidoglycolate hydrolase,0,1,0,0,1
COG3195,S,Uncharacterized protein conserved in bacteria,0,2,14,1,17
COG3196,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3197,P,"Uncharacterized protein, possibly involved in nitrogen fixation",0,0,0,0,0
COG3198,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3199,S,Uncharacterized conserved protein,0,1,0,0,1
COG3200,E,3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase,0,1,17,2,20
COG3201,H,Nicotinamide mononucleotide transporter,0,1,15,1,17
COG3202,C,ATP/ADP translocase,0,0,0,2,2
COG3203,M,Outer membrane protein (porin),0,0,0,0,0
COG3204,S,Uncharacterized protein conserved in bacteria,0,5,0,0,5
COG3205,S,Predicted membrane protein,0,0,0,0,0
COG3206,M,Uncharacterized protein involved in exopolysaccharide biosynthesis,0,4,0,4,8
COG3207,Q,Pyoverdine/dityrosine biosynthesis protein,0,0,0,0,0
COG3208,Q,Predicted thioesterase involved in non-ribosomal peptide biosynthesis,0,6,0,0,6
COG3209,M,Rhs family protein,0,8,0,1,9
COG3210,U,Large exoproteins involved in heme utilization or adhesion,0,0,0,0,0
COG3211,R,Predicted phosphatase,0,2,14,4,20
COG3212,S,Predicted membrane protein,0,2,0,0,2
COG3213,P,Uncharacterized protein involved in response to NO,0,0,0,2,2
COG3214,S,Uncharacterized protein conserved in bacteria,0,1,27,1,29
COG3215,NU,Tfp pilus assembly protein PilZ,0,1,0,0,1
COG3216,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3217,R,Uncharacterized Fe-S protein,0,2,0,3,5
COG3218,R,"ABC-type uncharacterized transport system, auxiliary component",0,2,0,0,2
COG3219,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3220,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3221,P,"ABC-type phosphate/phosphonate transport system, periplasmic component",0,3,0,2,5
COG3222,S,Uncharacterized protein conserved in bacteria,4,0,0,2,6
COG3223,S,Predicted membrane protein,0,1,0,0,1
COG3224,S,Uncharacterized protein conserved in bacteria,0,2,1,3,6
COG3225,N,"ABC-type uncharacterized transport system involved in gliding motility, auxiliary component",0,0,0,0,0
COG3226,S,Uncharacterized protein conserved in bacteria,0,1,15,0,16
COG3227,E,Zinc metalloprotease (elastase),0,0,0,2,2
COG3228,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3230,P,Heme oxygenase,0,1,0,0,1
COG3231,J,Aminoglycoside phosphotransferase,0,0,0,0,0
COG3232,E,5-carboxymethyl-2-hydroxymuconate isomerase,0,4,0,0,4
COG3233,R,Predicted deacetylase,0,1,0,1,2
COG3234,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3235,S,Predicted membrane protein,0,0,0,0,0
COG3236,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3237,S,Uncharacterized protein conserved in bacteria,1,0,0,0,1
COG3238,S,Uncharacterized protein conserved in bacteria,0,2,19,0,21
COG3239,I,Fatty acid desaturase,1,4,15,4,24
COG3240,IR,Phospholipase/lecithinase/hemolysin,0,1,0,1,2
COG3241,C,Azurin,0,1,0,0,1
COG3242,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3243,I,Poly(3-hydroxyalkanoate) synthetase,0,5,0,4,9
COG3245,C,Cytochrome c5,0,1,0,0,1
COG3246,S,Uncharacterized conserved protein,0,5,0,1,6
COG3247,S,Uncharacterized conserved protein,0,0,0,1,1
COG3248,M,Nucleoside-binding outer membrane protein,0,4,0,0,4
COG3249,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3250,G,Beta-galactosidase/beta-glucuronidase,0,4,0,18,22
COG3251,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG3252,H,Methenyltetrahydromethanopterin cyclohydrolase,0,0,0,0,0
COG3253,S,Uncharacterized conserved protein,0,1,15,5,21
COG3254,S,Uncharacterized conserved protein,0,0,0,0,0
COG3255,I,Putative sterol carrier protein,1,0,0,0,1
COG3256,P,Nitric oxide reductase large subunit,9,5,4,4,22
COG3257,R,"Uncharacterized protein, possibly involved in glyoxylate utilization",0,0,14,1,15
COG3258,C,Cytochrome c,0,0,0,1,1
COG3259,C,"Coenzyme F420-reducing hydrogenase, alpha subunit",0,0,0,0,0
COG3260,C,"Ni,Fe-hydrogenase III small subunit",0,0,0,0,0
COG3261,C,"Ni,Fe-hydrogenase III large subunit",0,0,0,0,0
COG3262,C,"Ni,Fe-hydrogenase III component G",0,0,0,0,0
COG3263,P,NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain,0,4,0,1,5
COG3264,M,Small-conductance mechanosensitive channel,0,6,0,5,11
COG3265,G,Gluconate kinase,0,1,26,2,29
COG3266,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3267,U,"Type II secretory pathway, component ExeA (predicted ATPase)",1,2,1,11,15
COG3268,S,Uncharacterized conserved protein,0,0,0,2,2
COG3269,R,"Predicted RNA-binding protein, contains TRAM domain",0,0,1,6,7
COG3270,S,Uncharacterized conserved protein,0,0,0,0,0
COG3271,R,Predicted double-glycine peptidase,0,1,0,0,1
COG3272,S,Uncharacterized conserved protein,0,1,0,0,1
COG3273,S,Uncharacterized conserved protein,0,0,0,1,1
COG3274,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3275,T,Putative regulator of cell autolysis,0,3,15,3,21
COG3276,J,Selenocysteine-specific translation elongation factor,2,1,2,3,8
COG3277,J,RNA-binding protein involved in rRNA processing,0,0,0,1,1
COG3278,O,"Cbb3-type cytochrome oxidase, subunit 1",0,7,0,1,8
COG3279,KT,Response regulator of the LytR/AlgR family,1,3,16,6,26
COG3280,G,Maltooligosyl trehalose synthase,1,5,0,24,30
COG3281,G,"Uncharacterized protein, probably involved in trehalose biosynthesis",0,2,0,5,7
COG3283,KE,Transcriptional regulator of aromatic amino acids metabolism,0,3,0,0,3
COG3284,QK,Transcriptional activator of acetoin/glycerol metabolism,2,5,31,3,41
COG3285,L,Predicted eukaryotic-type DNA primase,1,4,2,12,19
COG3286,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3287,S,Uncharacterized conserved protein,0,1,0,0,1
COG3288,C,NAD/NADP transhydrogenase alpha subunit,1,2,0,6,9
COG3290,T,Signal transduction histidine kinase regulating citrate/malate metabolism,0,0,63,16,79
COG3291,R,FOG: PKD repeat,0,1,0,1,2
COG3292,T,Predicted periplasmic ligand-binding sensor domain,1,0,0,4,5
COG3293,L,Transposase and inactivated derivatives,5,3,7,20,35
COG3294,S,Uncharacterized conserved protein,0,0,0,0,0
COG3295,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3296,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3297,U,"Type II secretory pathway, component PulL",0,0,0,0,0
COG3298,L,Predicted 3'-5' exonuclease related to the exonuclease domain of PolB,0,0,0,0,0
COG3299,S,Uncharacterized homolog of phage Mu protein gp47,0,2,0,0,2
COG3300,T,MHYT domain (predicted integral membrane sensor domain),0,3,0,1,4
COG3301,P,"Formate-dependent nitrite reductase, membrane component",0,0,0,0,0
COG3302,R,DMSO reductase anchor subunit,0,0,0,0,0
COG3303,P,"Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit",0,0,0,0,0
COG3304,S,Predicted membrane protein,1,0,15,0,16
COG3305,S,Predicted membrane protein,0,0,0,0,0
COG3306,M,Glycosyltransferase involved in LPS biosynthesis,0,1,0,0,1
COG3307,M,Lipid A core - O-antigen ligase and related enzymes,0,0,12,1,13
COG3308,S,Predicted membrane protein,0,1,0,0,1
COG3309,S,Uncharacterized virulence-associated protein D,0,0,0,0,0
COG3310,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3311,K,Predicted transcriptional regulator,0,0,0,0,0
COG3312,C,"F0F1-type ATP synthase, subunit I",0,1,0,0,1
COG3313,R,Predicted Fe-S protein,0,1,0,0,1
COG3314,S,Uncharacterized protein conserved in bacteria,0,0,11,0,11
COG3315,Q,O-Methyltransferase involved in polyketide biosynthesis,0,0,0,3,3
COG3316,L,Transposase and inactivated derivatives,0,0,0,1,1
COG3317,M,Uncharacterized lipoprotein,0,2,0,0,2
COG3318,R,Predicted metal-binding protein related to the C-terminal domain of SecA,0,2,0,1,3
COG3319,Q,Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases,1,1,0,1,3
COG3320,Q,Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes,0,0,0,2,2
COG3321,Q,Polyketide synthase modules and related proteins,0,14,0,6,20
COG3322,T,Predicted periplasmic ligand-binding sensor domain,0,1,0,0,1
COG3323,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3324,R,Predicted enzyme related to lactoylglutathione lyase,0,2,32,15,49
COG3325,G,Chitinase,0,0,0,10,10
COG3326,S,Predicted membrane protein,0,1,0,0,1
COG3327,K,Phenylacetic acid-responsive transcriptional repressor,0,0,44,2,46
COG3328,L,Transposase and inactivated derivatives,10,9,7,16,42
COG3329,R,Predicted permease,0,0,0,0,0
COG3330,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3331,R,"Penicillin-binding protein-related factor A, putative recombinase",0,0,0,0,0
COG3332,S,Uncharacterized conserved protein,0,4,0,0,4
COG3333,S,Uncharacterized protein conserved in bacteria,1,5,80,23,109
COG3334,S,Uncharacterized conserved protein,0,0,0,0,0
COG3335,L,Transposase and inactivated derivatives,4,4,0,6,14
COG3336,S,Predicted membrane protein,0,0,16,2,18
COG3337,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG3338,P,Carbonic anhydrase,0,0,0,0,0
COG3339,S,Uncharacterized conserved protein,0,0,5,3,8
COG3340,E,Peptidase E,0,0,2,2,4
COG3341,R,Predicted double-stranded RNA/RNA-DNA hybrid binding protein,0,0,0,0,0
COG3342,S,Uncharacterized conserved protein,0,1,0,2,3
COG3343,K,"DNA-directed RNA polymerase, delta subunit",0,0,0,0,0
COG3344,L,Retron-type reverse transcriptase,1,4,13,16,34
COG3345,G,Alpha-galactosidase,0,0,0,0,0
COG3346,S,Uncharacterized conserved protein,0,1,21,1,23
COG3347,S,Uncharacterized conserved protein,6,0,0,2,8
COG3349,S,Uncharacterized conserved protein,0,1,0,0,1
COG3350,S,Uncharacterized conserved protein,0,0,0,1,1
COG3351,N,Putative archaeal flagellar protein D/E,0,0,0,0,0
COG3352,N,Putative archaeal flagellar protein C,0,0,0,0,0
COG3353,N,Putative archaeal flagellar protein F,0,0,0,0,0
COG3354,N,Putative archaeal flagellar protein G,0,0,0,0,0
COG3355,K,Predicted transcriptional regulator,0,0,0,0,0
COG3356,S,Predicted membrane protein,0,0,0,4,4
COG3357,K,Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon,0,0,0,0,0
COG3358,S,Uncharacterized conserved protein,0,1,0,1,2
COG3359,L,Predicted exonuclease,0,0,0,0,0
COG3360,S,Uncharacterized conserved protein,0,2,0,2,4
COG3361,S,Uncharacterized conserved protein,0,0,0,1,1
COG3363,F,Archaeal IMP cyclohydrolase,0,0,0,0,0
COG3364,R,Zn-ribbon containing protein,0,0,0,0,0
COG3365,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3366,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3367,S,Uncharacterized conserved protein,0,0,0,1,1
COG3368,R,Predicted permease,0,0,0,0,0
COG3369,S,Uncharacterized conserved protein,0,0,9,6,15
COG3370,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3371,S,Predicted membrane protein,0,0,0,0,0
COG3372,S,Uncharacterized conserved protein,0,0,0,7,7
COG3373,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3374,S,Predicted membrane protein,0,0,0,0,0
COG3375,S,Uncharacterized conserved protein,0,2,0,1,3
COG3376,P,High-affinity nickel permease,0,0,0,4,4
COG3377,S,Uncharacterized conserved protein,0,0,0,0,0
COG3378,R,Predicted ATPase,0,3,2,5,10
COG3379,S,Uncharacterized conserved protein,0,1,0,0,1
COG3380,R,Predicted NAD/FAD-dependent oxidoreductase,0,2,0,0,2
COG3381,R,Uncharacterized component of anaerobic dehydrogenases,0,0,0,0,0
COG3382,S,Uncharacterized conserved protein,0,0,0,0,0
COG3383,R,Uncharacterized anaerobic dehydrogenase,3,12,15,23,53
COG3384,S,Uncharacterized conserved protein,0,3,18,1,22
COG3385,L,FOG: Transposase and inactivated derivatives,0,0,0,0,0
COG3386,G,Gluconolactonase,2,5,0,6,13
COG3387,G,Glucoamylase and related glycosyl hydrolases,0,4,34,18,56
COG3388,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3389,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3390,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3391,S,Uncharacterized conserved protein,0,7,0,21,28
COG3392,L,Adenine-specific DNA methylase,1,0,0,0,1
COG3393,R,Predicted acetyltransferase,0,0,15,1,16
COG3394,S,Uncharacterized protein conserved in bacteria,0,1,0,3,4
COG3395,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3396,S,Uncharacterized conserved protein,0,0,28,1,29
COG3397,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3398,S,Uncharacterized protein conserved in archaea,0,0,0,4,4
COG3399,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3400,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3401,R,Fibronectin type 3 domain-containing protein,0,0,0,0,0
COG3402,S,Uncharacterized conserved protein,0,0,15,0,15
COG3403,S,Uncharacterized conserved protein,0,0,0,0,0
COG3404,E,Methenyl tetrahydrofolate cyclohydrolase,0,0,28,2,30
COG3405,G,Endoglucanase Y,1,0,0,0,1
COG3407,I,Mevalonate pyrophosphate decarboxylase,0,0,0,0,0
COG3408,G,Glycogen debranching enzyme,0,1,1,15,17
COG3409,M,Putative peptidoglycan-binding domain-containing protein,1,0,0,2,3
COG3410,S,Uncharacterized conserved protein,0,0,0,0,0
COG3411,C,Ferredoxin,0,1,0,0,1
COG3412,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3413,R,Predicted DNA binding protein,0,0,0,0,0
COG3414,G,"Phosphotransferase system, galactitol-specific IIB component",0,0,0,0,0
COG3415,L,Transposase and inactivated derivatives,4,2,2,11,19
COG3416,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3417,R,Collagen-binding surface adhesin SpaP (antigen I/II family),0,0,0,0,0
COG3418,NUO,Flagellar biosynthesis/type III secretory pathway chaperone,0,0,0,0,0
COG3419,NU,"Tfp pilus assembly protein, tip-associated adhesin PilY1",0,1,0,0,1
COG3420,P,Nitrous oxidase accessory protein,0,2,0,0,2
COG3421,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3422,S,Uncharacterized conserved protein,0,1,0,0,1
COG3423,K,Predicted transcriptional regulator,0,0,0,0,0
COG3424,Q,Predicted naringenin-chalcone synthase,0,1,16,1,18
COG3425,I,3-hydroxy-3-methylglutaryl CoA synthase,3,0,2,3,8
COG3426,C,Butyrate kinase,0,0,0,0,0
COG3427,S,Uncharacterized conserved protein,0,2,0,4,6
COG3428,S,Predicted membrane protein,0,1,15,0,16
COG3429,G,Glucose-6-P dehydrogenase subunit,0,0,17,1,18
COG3430,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3431,S,Predicted membrane protein,0,1,0,0,1
COG3432,K,Predicted transcriptional regulator,0,0,1,6,7
COG3433,Q,Aryl carrier domain,0,0,0,0,0
COG3434,T,Predicted signal transduction protein containing EAL and modified HD-GYP domains,0,0,0,0,0
COG3435,Q,"Gentisate 1,2-dioxygenase",0,0,0,2,2
COG3436,L,Transposase and inactivated derivatives,0,0,0,1,1
COG3437,KT,Response regulator containing a CheY-like receiver domain and an HD-GYP domain,2,10,0,14,26
COG3439,S,Uncharacterized conserved protein,0,0,0,1,1
COG3440,V,Predicted restriction endonuclease,0,0,14,0,14
COG3442,R,Predicted glutamine amidotransferase,0,0,0,0,0
COG3443,R,Predicted periplasmic or secreted protein,0,0,0,0,0
COG3444,G,"Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB",0,0,0,0,0
COG3445,R,Acid-induced glycyl radical enzyme,0,0,0,0,0
COG3447,T,Predicted integral membrane sensor domain,0,1,0,5,6
COG3448,T,CBS-domain-containing membrane protein,1,1,0,1,3
COG3449,L,DNA gyrase inhibitor,0,0,0,0,0
COG3450,R,Predicted enzyme of the cupin superfamily,0,0,16,0,16
COG3451,U,"Type IV secretory pathway, VirB4 components",0,0,0,0,0
COG3452,T,Predicted periplasmic ligand-binding sensor domain,0,0,0,0,0
COG3453,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3454,P,Metal-dependent hydrolase involved in phosphonate metabolism,0,0,0,0,0
COG3455,S,Uncharacterized protein conserved in bacteria,0,6,0,0,6
COG3456,T,"Uncharacterized conserved protein, contains FHA domain",0,2,0,0,2
COG3457,E,Predicted amino acid racemase,0,0,0,0,0
COG3458,Q,Acetyl esterase (deacetylase),0,0,0,2,2
COG3459,G,Cellobiose phosphorylase,0,7,0,24,31
COG3460,Q,Uncharacterized enzyme of phenylacetate metabolism,0,0,14,0,14
COG3461,S,Uncharacterized conserved protein,0,0,0,0,0
COG3462,S,Predicted membrane protein,0,0,0,0,0
COG3463,S,Predicted membrane protein,0,0,0,1,1
COG3464,L,Transposase and inactivated derivatives,0,0,7,9,16
COG3465,S,Uncharacterized conserved protein,0,0,0,0,0
COG3466,S,Putative transposon-encoded protein,0,0,0,0,0
COG3467,R,Predicted flavin-nucleotide-binding protein,0,1,17,7,25
COG3468,MU,"Type V secretory pathway, adhesin AidA",0,0,0,0,0
COG3469,G,Chitinase,0,0,0,0,0
COG3470,P,Uncharacterized protein probably involved in high-affinity Fe2+ transport,0,1,0,0,1
COG3471,S,Predicted periplasmic/secreted protein,0,1,0,0,1
COG3472,S,Uncharacterized conserved protein,0,0,0,0,0
COG3473,Q,Maleate cis-trans isomerase,2,0,0,0,2
COG3474,C,Cytochrome c2,0,0,0,1,1
COG3475,M,LPS biosynthesis protein,0,0,0,0,0
COG3476,T,Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog),0,0,0,1,1
COG3477,S,Predicted periplasmic/secreted protein,0,0,0,0,0
COG3478,R,Predicted nucleic-acid-binding protein containing a Zn-ribbon domain,0,0,0,0,0
COG3479,Q,Phenolic acid decarboxylase,0,0,0,0,0
COG3480,T,Predicted secreted protein containing a PDZ domain,0,0,14,0,14
COG3481,R,Predicted HD-superfamily hydrolase,1,0,0,2,3
COG3482,S,Uncharacterized conserved protein,0,0,0,10,10
COG3483,E,"Tryptophan 2,3-dioxygenase (vermilion)",0,0,17,3,20
COG3484,O,Predicted proteasome-type protease,0,0,0,1,1
COG3485,Q,"Protocatechuate 3,4-dioxygenase beta subunit",1,10,50,4,65
COG3486,Q,Lysine/ornithine N-monooxygenase,0,0,11,1,12
COG3487,P,Uncharacterized iron-regulated protein,0,1,0,0,1
COG3488,C,Predicted thiol oxidoreductase,0,9,0,3,12
COG3489,R,Predicted periplasmic lipoprotein,0,3,0,0,3
COG3490,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3491,R,Isopenicillin N synthase and related dioxygenases,0,4,15,1,20
COG3492,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3493,C,Na+/citrate symporter,0,0,16,0,16
COG3494,S,Uncharacterized protein conserved in bacteria,5,1,0,2,8
COG3495,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3496,S,Uncharacterized conserved protein,0,0,0,0,0
COG3497,R,Phage tail sheath protein FI,0,1,0,1,2
COG3498,R,Phage tail tube protein FII,0,0,0,0,0
COG3499,R,Phage protein U,0,0,0,0,0
COG3500,R,Phage protein D,0,0,0,0,0
COG3501,S,Uncharacterized protein conserved in bacteria,0,17,0,0,17
COG3502,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3503,S,Predicted membrane protein,0,2,0,2,4
COG3504,U,"Type IV secretory pathway, VirB9 components",0,0,0,0,0
COG3505,U,"Type IV secretory pathway, VirD4 components",0,1,5,6,12
COG3506,S,Uncharacterized conserved protein,0,0,0,0,0
COG3507,G,Beta-xylosidase,0,0,0,4,4
COG3508,Q,"Homogentisate 1,2-dioxygenase",0,2,4,6,12
COG3509,Q,Poly(3-hydroxybutyrate) depolymerase,0,1,0,0,1
COG3510,V,Cephalosporin hydroxylase,0,0,2,1,3
COG3511,M,Phospholipase C,0,1,0,5,6
COG3512,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3513,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3514,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3515,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3516,S,Uncharacterized protein conserved in bacteria,0,2,0,1,3
COG3517,S,Uncharacterized protein conserved in bacteria,0,5,0,0,5
COG3518,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3519,S,Uncharacterized protein conserved in bacteria,0,6,0,0,6
COG3520,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG3521,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3522,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3523,S,Uncharacterized protein conserved in bacteria,3,7,0,0,10
COG3524,M,Capsule polysaccharide export protein,0,0,0,0,0
COG3525,G,N-acetyl-beta-hexosaminidase,0,0,0,5,5
COG3526,O,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3527,Q,Alpha-acetolactate decarboxylase,0,0,0,2,2
COG3528,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3529,R,Predicted nucleic-acid-binding protein containing a Zn-ribbon domain,0,1,0,0,1
COG3530,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3531,O,Predicted protein-disulfide isomerase,0,2,0,0,2
COG3533,S,Uncharacterized protein conserved in bacteria,0,1,0,3,4
COG3534,G,Alpha-L-arabinofuranosidase,0,8,0,7,15
COG3535,S,Uncharacterized conserved protein,0,0,0,0,0
COG3536,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3537,G,"Putative alpha-1,2-mannosidase",0,3,0,2,5
COG3538,S,Uncharacterized conserved protein,0,0,0,0,0
COG3539,NU,"P pilus assembly protein, pilin FimA",0,0,0,0,0
COG3540,P,Phosphodiesterase/alkaline phosphatase D,1,2,29,15,47
COG3541,R,Predicted nucleotidyltransferase,0,0,0,0,0
COG3542,S,Uncharacterized conserved protein,0,0,0,4,4
COG3543,S,Uncharacterized conserved protein,0,0,0,0,0
COG3544,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3545,R,Predicted esterase of the alpha/beta hydrolase fold,0,1,0,0,1
COG3546,P,Mn-containing catalase,0,2,0,0,2
COG3547,L,Transposase and inactivated derivatives,3,9,10,31,53
COG3548,S,Predicted integral membrane protein,0,3,15,4,22
COG3549,R,Plasmid maintenance system killer protein,0,0,0,0,0
COG3550,R,Uncharacterized protein related to capsule biosynthesis enzymes,0,0,30,1,31
COG3551,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3552,R,Protein containing von Willebrand factor type A (vWA) domain,0,1,0,3,4
COG3553,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3554,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3555,O,Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases,0,4,0,0,4
COG3556,S,Predicted membrane protein,0,1,0,0,1
COG3557,J,Uncharacterized domain/protein associated with RNAses G and E,0,1,16,0,17
COG3558,S,Uncharacterized protein conserved in bacteria,0,3,0,2,5
COG3559,M,Putative exporter of polyketide antibiotics,0,0,0,0,0
COG3560,R,Predicted oxidoreductase related to nitroreductase,0,0,0,0,0
COG3561,K,Phage anti-repressor protein,0,0,0,0,0
COG3562,M,Capsule polysaccharide export protein,0,0,0,0,0
COG3563,M,Capsule polysaccharide export protein,0,0,0,0,0
COG3564,S,Uncharacterized protein conserved in bacteria,0,0,16,1,17
COG3565,R,Predicted dioxygenase of extradiol dioxygenase family,0,2,0,0,2
COG3566,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3567,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3568,R,Metal-dependent hydrolase,0,6,0,1,7
COG3569,L,Topoisomerase IB,0,2,0,7,9
COG3570,V,Streptomycin 6-kinase,0,1,0,0,1
COG3571,R,Predicted hydrolase of the alpha/beta-hydrolase fold,0,1,14,1,16
COG3572,H,Gamma-glutamylcysteine synthetase,1,0,0,0,1
COG3573,R,Predicted oxidoreductase,0,0,13,0,13
COG3575,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3576,R,Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase,1,1,0,1,3
COG3577,R,Predicted aspartyl protease,0,1,0,0,1
COG3579,E,Aminopeptidase C,0,0,0,0,0
COG3580,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3581,S,Uncharacterized protein conserved in bacteria,0,0,0,3,3
COG3582,R,Predicted nucleic acid binding protein containing the AN1-type Zn-finger,0,0,0,0,0
COG3583,S,Uncharacterized protein conserved in bacteria,0,0,9,0,9
COG3584,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3585,H,Molybdopterin-binding protein,0,2,0,0,2
COG3586,S,Uncharacterized conserved protein,0,0,0,0,0
COG3587,V,Restriction endonuclease,0,0,25,2,27
COG3588,G,"Fructose-1,6-bisphosphate aldolase",0,0,0,5,5
COG3589,S,Uncharacterized conserved protein,0,0,0,0,0
COG3590,O,Predicted metalloendopeptidase,0,1,17,29,47
COG3591,E,V8-like Glu-specific endopeptidase,0,1,0,1,2
COG3592,S,Uncharacterized conserved protein,0,0,0,5,5
COG3593,L,Predicted ATP-dependent endonuclease of the OLD family,0,0,14,0,14
COG3594,G,Fucose 4-O-acetylase and related acetyltransferases,0,0,0,0,0
COG3595,S,Uncharacterized conserved protein,0,0,0,0,0
COG3596,R,Predicted GTPase,0,0,0,0,0
COG3597,S,Uncharacterized protein/domain associated with GTPases,0,0,0,0,0
COG3598,L,RecA-family ATPase,0,0,0,0,0
COG3599,D,Cell division initiation protein,0,0,0,0,0
COG3600,S,Uncharacterized phage-associated protein,0,0,0,0,0
COG3601,S,Predicted membrane protein,0,0,0,0,0
COG3602,S,Uncharacterized protein conserved in bacteria,1,0,0,0,1
COG3603,S,Uncharacterized conserved protein,0,0,0,0,0
COG3604,KT,"Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains",3,13,0,15,31
COG3605,T,Signal transduction protein containing GAF and PtsI domains,3,6,0,2,11
COG3607,R,Predicted lactoylglutathione lyase,0,0,7,1,8
COG3608,R,Predicted deacylase,0,4,0,1,5
COG3609,K,Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain,0,0,0,0,0
COG3610,S,Uncharacterized conserved protein,0,0,2,0,2
COG3611,L,Replication initiation/membrane attachment protein,0,0,0,0,0
COG3612,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG3613,F,Nucleoside 2-deoxyribosyltransferase,0,0,0,0,0
COG3614,T,Predicted periplasmic ligand-binding sensor domain,0,1,0,0,1
COG3615,P,"Uncharacterized protein/domain, possibly involved in tellurite resistance",0,0,0,0,0
COG3616,E,Predicted amino acid aldolase or racemase,0,1,20,2,23
COG3617,K,Prophage antirepressor,0,3,0,0,3
COG3618,R,Predicted metal-dependent hydrolase of the TIM-barrel fold,0,1,0,2,3
COG3619,S,Predicted membrane protein,0,2,17,0,19
COG3620,K,Predicted transcriptional regulator with C-terminal CBS domains,0,0,3,2,5
COG3621,R,Patatin,0,0,0,0,0
COG3622,G,Hydroxypyruvate isomerase,0,3,11,2,16
COG3623,G,Putative L-xylulose-5-phosphate 3-epimerase,0,0,0,0,0
COG3624,P,Uncharacterized enzyme of phosphonate metabolism,0,0,0,0,0
COG3625,P,Uncharacterized enzyme of phosphonate metabolism,0,0,0,0,0
COG3626,P,Uncharacterized enzyme of phosphonate metabolism,0,0,0,0,0
COG3627,P,Uncharacterized enzyme of phosphonate metabolism,0,0,0,0,0
COG3628,R,Phage baseplate assembly protein W,0,0,0,0,0
COG3629,T,DNA-binding transcriptional activator of the SARP family,0,0,0,1,1
COG3630,C,"Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit",0,0,0,0,0
COG3631,R,Ketosteroid isomerase-related protein,0,2,0,2,4
COG3633,E,Na+/serine symporter,0,1,0,0,1
COG3634,O,"Alkyl hydroperoxide reductase, large subunit",0,2,0,0,2
COG3635,G,"Predicted phosphoglycerate mutase, AP superfamily",0,1,2,4,7
COG3636,K,Predicted transcriptional regulator,0,1,0,0,1
COG3637,M,Opacity protein and related surface antigens,0,1,0,0,1
COG3638,P,"ABC-type phosphate/phosphonate transport system, ATPase component",0,2,0,0,2
COG3639,P,"ABC-type phosphate/phosphonate transport system, permease component",0,1,0,0,1
COG3640,D,CO dehydrogenase maturation factor,0,0,0,0,0
COG3641,R,"Predicted membrane protein, putative toxin regulator",0,0,0,0,0
COG3642,T,Mn2+-dependent serine/threonine protein kinase,0,1,0,3,4
COG3643,E,Glutamate formiminotransferase,0,1,0,4,5
COG3644,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3645,S,Uncharacterized phage-encoded protein,0,0,0,0,0
COG3646,S,Uncharacterized phage-encoded protein,0,0,9,0,9
COG3647,S,Predicted membrane protein,0,1,0,0,1
COG3648,Q,Uricase (urate oxidase),0,0,16,0,16
COG3649,L,Uncharacterized protein predicted to be involved in DNA repair,0,0,0,0,0
COG3650,S,Predicted membrane protein,0,0,0,0,0
COG3651,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3652,S,Predicted outer membrane protein,1,2,0,0,3
COG3653,Q,N-acyl-D-aspartate/D-glutamate deacylase,1,8,0,9,18
COG3654,R,Prophage maintenance system killer protein,0,0,0,1,1
COG3655,K,Predicted transcriptional regulator,0,0,40,1,41
COG3656,S,Predicted periplasmic protein,0,0,0,0,0
COG3657,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3658,C,Cytochrome b,0,0,0,0,0
COG3659,M,Carbohydrate-selective porin,1,5,0,3,9
COG3660,M,Predicted nucleoside-diphosphate-sugar epimerase,0,0,0,0,0
COG3661,G,Alpha-glucuronidase,0,0,0,3,3
COG3662,S,Uncharacterized protein conserved in bacteria,0,0,16,3,19
COG3663,L,G:T/U mismatch-specific DNA glycosylase,0,3,0,0,3
COG3664,G,Beta-xylosidase,0,0,0,0,0
COG3665,S,Uncharacterized conserved protein,0,3,0,0,3
COG3666,L,Transposase and inactivated derivatives,5,9,6,12,32
COG3667,P,Uncharacterized protein involved in copper resistance,0,1,0,0,1
COG3668,R,Plasmid stabilization system protein,0,0,0,0,0
COG3669,G,Alpha-L-fucosidase,0,1,0,2,3
COG3670,Q,"Lignostilbene-alpha,beta-dioxygenase and related enzymes",0,0,0,0,0
COG3671,S,Predicted membrane protein,0,0,0,1,1
COG3672,S,Predicted periplasmic protein,0,3,0,1,4
COG3673,S,Uncharacterized conserved protein,0,0,0,0,0
COG3675,I,Predicted lipase,0,0,0,0,0
COG3676,L,Transposase and inactivated derivatives,0,1,0,0,1
COG3677,L,Transposase and inactivated derivatives,0,0,2,4,6
COG3678,UNTP,"P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein",0,1,0,0,1
COG3679,S,Uncharacterized conserved protein,0,0,0,0,0
COG3680,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3681,S,Uncharacterized conserved protein,0,0,0,0,0
COG3682,K,Predicted transcriptional regulator,1,2,14,6,23
COG3683,R,"ABC-type uncharacterized transport system, periplasmic component",0,0,0,0,0
COG3684,G,"Tagatose-1,6-bisphosphate aldolase",0,0,0,1,1
COG3685,S,Uncharacterized protein conserved in bacteria,0,0,0,7,7
COG3686,S,Predicted membrane protein,0,2,0,0,2
COG3687,R,Predicted metal-dependent hydrolase,0,0,0,0,0
COG3688,R,Predicted RNA-binding protein containing a PIN domain,0,0,0,4,4
COG3689,S,Predicted membrane protein,0,0,0,0,0
COG3691,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3692,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3693,G,"Beta-1,4-xylanase",0,0,0,0,0
COG3694,R,"ABC-type uncharacterized transport system, permease component",0,1,2,3,6
COG3695,L,Predicted methylated DNA-protein cysteine methyltransferase,0,1,11,0,12
COG3696,P,Putative silver efflux pump,7,18,2,39,66
COG3697,HI,Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase),0,0,0,0,0
COG3698,S,Predicted periplasmic protein,0,0,0,0,0
COG3700,R,Acid phosphatase (class B),0,0,0,0,0
COG3701,U,"Type IV secretory pathway, TrbF components",0,0,0,0,0
COG3702,U,"Type IV secretory pathway, VirB3 components",0,0,0,0,0
COG3703,P,Uncharacterized protein involved in cation transport,0,1,0,1,2
COG3704,U,"Type IV secretory pathway, VirB6 components",0,0,0,0,0
COG3705,E,ATP phosphoribosyltransferase involved in histidine biosynthesis,0,1,0,0,1
COG3706,T,Response regulator containing a CheY-like receiver domain and a GGDEF domain,6,15,0,17,38
COG3707,T,Response regulator with putative antiterminator output domain,0,0,7,0,7
COG3708,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG3709,P,Uncharacterized component of phosphonate metabolism,0,1,0,0,1
COG3710,K,DNA-binding winged-HTH domains,4,5,1,11,21
COG3711,K,Transcriptional antiterminator,0,0,0,0,0
COG3712,PT,"Fe2+-dicitrate sensor, membrane component",2,7,0,0,9
COG3713,M,Outer membrane protein V,0,0,0,0,0
COG3714,S,Predicted membrane protein,0,0,15,0,15
COG3715,G,"Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC",0,0,0,0,0
COG3716,G,"Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID",0,0,0,0,0
COG3717,G,5-keto 4-deoxyuronate isomerase,0,0,0,0,0
COG3718,G,Uncharacterized enzyme involved in inositol metabolism,0,2,0,0,2
COG3719,J,Ribonuclease I,0,1,0,0,1
COG3720,P,Putative heme degradation protein,0,0,0,0,0
COG3721,P,Putative heme iron utilization protein,0,0,0,0,0
COG3722,K,Transcriptional regulator,0,0,0,0,0
COG3723,L,Recombinational DNA repair protein (RecE pathway),0,2,0,0,2
COG3724,E,Succinylarginine dihydrolase,0,1,0,0,1
COG3725,V,Membrane protein required for beta-lactamase induction,0,1,0,0,1
COG3726,R,Uncharacterized membrane protein affecting hemolysin expression,0,1,0,0,1
COG3727,L,DNA G:T-mismatch repair endonuclease,0,0,0,0,0
COG3728,L,"Phage terminase, small subunit",0,1,0,0,1
COG3729,R,General stress protein,0,0,0,0,0
COG3730,G,Phosphotransferase system sorbitol-specific component IIC,0,0,0,0,0
COG3731,G,Phosphotransferase system sorbitol-specific component IIA,0,0,0,0,0
COG3732,G,Phosphotransferase system sorbitol-specific component IIBC,0,0,0,0,0
COG3733,Q,Cu2+-containing amine oxidase,0,0,17,2,19
COG3734,G,2-keto-3-deoxy-galactonokinase,0,1,0,0,1
COG3735,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3736,U,"Type IV secretory pathway, component VirB8",0,0,0,0,0
COG3737,S,Uncharacterized conserved protein,0,0,0,0,0
COG3738,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3739,S,Uncharacterized integral membrane protein,0,0,0,0,0
COG3740,R,Phage head maturation protease,0,0,3,0,3
COG3741,E,N-formylglutamate amidohydrolase,0,1,0,0,1
COG3742,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3743,S,Uncharacterized conserved protein,0,0,0,0,0
COG3744,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3745,U,Flp pilus assembly protein CpaB,0,3,0,1,4
COG3746,P,Phosphate-selective porin,0,0,0,2,2
COG3747,L,"Phage terminase, small subunit",0,0,13,0,13
COG3748,S,Predicted membrane protein,0,1,0,3,4
COG3749,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3750,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3751,O,Predicted proline hydroxylase,0,2,0,0,2
COG3752,S,Predicted membrane protein,0,0,0,1,1
COG3753,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3754,M,Lipopolysaccharide biosynthesis protein,0,0,0,0,0
COG3755,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3756,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3757,M,"Lyzozyme M1 (1,4-beta-N-acetylmuramidase)",1,0,4,5,10
COG3758,S,Uncharacterized protein conserved in bacteria,0,1,14,0,15
COG3759,S,Predicted membrane protein,0,0,6,1,7
COG3760,S,Uncharacterized conserved protein,0,0,0,0,0
COG3761,C,NADH:ubiquinone oxidoreductase 17.2 kD subunit,1,0,0,0,1
COG3762,S,Predicted membrane protein,0,1,0,3,4
COG3763,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3764,M,Sortase (surface protein transpeptidase),2,0,28,10,40
COG3765,M,Chain length determinant protein,0,0,0,0,0
COG3766,S,Predicted membrane protein,0,0,0,0,0
COG3767,S,Uncharacterized low-complexity protein,0,0,0,0,0
COG3768,S,Predicted membrane protein,0,0,0,0,0
COG3769,R,Predicted hydrolase (HAD superfamily),0,0,0,4,4
COG3770,M,Murein endopeptidase,0,0,0,0,0
COG3771,S,Predicted membrane protein,0,0,0,0,0
COG3772,R,Phage-related lysozyme (muraminidase),0,3,0,0,3
COG3773,M,Cell wall hydrolyses involved in spore germination,1,1,0,0,2
COG3774,M,Mannosyltransferase OCH1 and related enzymes,0,0,0,0,0
COG3775,G,"Phosphotransferase system, galactitol-specific IIC component",0,0,0,0,0
COG3776,S,Predicted membrane protein,0,1,0,0,1
COG3777,S,Uncharacterized conserved protein,0,1,0,0,1
COG3778,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3779,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3780,L,DNA endonuclease related to intein-encoded endonucleases,0,0,0,0,0
COG3781,S,Predicted membrane protein,0,2,0,0,2
COG3782,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3783,C,Soluble cytochrome b562,0,0,0,0,0
COG3784,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3785,S,Uncharacterized conserved protein,0,0,0,0,0
COG3786,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG3787,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3788,R,"Uncharacterized relative of glutathione S-transferase, MAPEG superfamily",0,0,0,0,0
COG3789,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3790,S,Predicted membrane protein,0,0,0,0,0
COG3791,S,Uncharacterized conserved protein,0,4,0,4,8
COG3792,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3793,P,Tellurite resistance protein,0,0,0,0,0
COG3794,C,Plastocyanin,3,1,2,9,15
COG3795,S,Uncharacterized protein conserved in bacteria,0,3,0,10,13
COG3797,S,Uncharacterized protein conserved in bacteria,0,0,14,3,17
COG3798,S,Uncharacterized protein conserved in bacteria,7,0,0,0,7
COG3799,E,Methylaspartate ammonia-lyase,0,0,0,0,0
COG3800,R,Predicted transcriptional regulator,0,0,14,1,15
COG3801,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3802,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG3803,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3804,S,Uncharacterized conserved protein related to dihydrodipicolinate reductase,0,0,0,0,0
COG3805,Q,Aromatic ring-cleaving dioxygenase,0,1,0,0,1
COG3806,T,Anti-sigma factor,0,0,0,0,0
COG3807,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3808,C,Inorganic pyrophosphatase,3,1,1,6,11
COG3809,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3811,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3812,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3813,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG3814,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3815,S,Predicted membrane protein,0,1,0,0,1
COG3816,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG3817,S,Predicted membrane protein,0,0,0,0,0
COG3818,R,"Predicted acetyltransferase, GNAT superfamily",0,0,0,0,0
COG3819,S,Predicted membrane protein,0,0,0,0,0
COG3820,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3821,S,Predicted membrane protein,0,1,0,0,1
COG3822,R,"ABC-type sugar transport system, auxiliary component",0,0,0,1,1
COG3823,O,Glutamine cyclotransferase,0,2,0,2,4
COG3824,S,Uncharacterized protein conserved in bacteria,0,0,10,0,10
COG3825,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3826,S,Uncharacterized protein conserved in bacteria,0,1,1,2,4
COG3827,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3828,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG3829,KT,"Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains",1,30,0,36,67
COG3830,T,ACT domain-containing protein,0,0,0,0,0
COG3831,S,Uncharacterized conserved protein,0,0,0,0,0
COG3832,S,Uncharacterized conserved protein,1,3,40,9,53
COG3833,G,"ABC-type maltose transport systems, permease component",0,0,20,1,21
COG3835,KT,Sugar diacid utilization regulator,0,2,31,1,34
COG3836,G,"2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase",0,2,38,5,45
COG3837,S,"Uncharacterized conserved protein, contains double-stranded beta-helix domain",0,0,1,2,3
COG3838,U,"Type IV secretory pathway, VirB2 components (pilins)",0,0,0,0,0
COG3839,G,"ABC-type sugar transport systems, ATPase components",1,11,17,9,38
COG3840,H,"ABC-type thiamine transport system, ATPase component",0,0,0,0,0
COG3842,E,"ABC-type spermidine/putrescine transport systems, ATPase components",1,30,35,17,83
COG3843,U,"Type IV secretory pathway, VirD2 components (relaxase)",0,0,0,0,0
COG3844,E,Kynureninase,0,1,27,7,35
COG3845,R,"ABC-type uncharacterized transport systems, ATPase components",0,3,24,7,34
COG3846,U,"Type IV secretory pathway, TrbL components",0,0,0,1,1
COG3847,U,"Flp pilus assembly protein, pilin Flp",0,0,0,0,0
COG3848,T,Phosphohistidine swiveling domain,0,0,0,0,0
COG3850,T,"Signal transduction histidine kinase, nitrate/nitrite-specific",0,3,0,5,8
COG3851,T,"Signal transduction histidine kinase, glucose-6-phosphate specific",0,0,1,1,2
COG3852,T,"Signal transduction histidine kinase, nitrogen specific",2,2,0,4,8
COG3853,P,Uncharacterized protein involved in tellurite resistance,0,1,0,0,1
COG3854,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3855,G,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3856,S,Uncharacterized conserved protein (small basic protein),0,0,0,0,0
COG3857,L,"ATP-dependent nuclease, subunit B",0,1,0,0,1
COG3858,R,Predicted glycosyl hydrolase,0,0,4,4,8
COG3859,S,Predicted membrane protein,0,0,0,0,0
COG3860,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3861,S,Uncharacterized protein conserved in bacteria,0,0,14,0,14
COG3862,S,Uncharacterized protein with conserved CXXC pairs,0,0,0,0,0
COG3863,S,Uncharacterized distant relative of cell wall-associated hydrolases,0,0,0,0,0
COG3864,S,Uncharacterized protein conserved in bacteria,1,0,0,0,1
COG3865,S,Uncharacterized protein conserved in bacteria,1,1,22,6,30
COG3866,G,Pectate lyase,0,0,0,0,0
COG3867,G,"Arabinogalactan endo-1,4-beta-galactosidase",0,0,0,0,0
COG3868,S,Uncharacterized conserved protein,0,0,0,0,0
COG3869,E,Arginine kinase,0,0,1,4,5
COG3870,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3871,R,Uncharacterized stress protein (general stress protein 26),0,0,14,2,16
COG3872,R,Predicted metal-dependent enzyme,0,1,0,4,5
COG3874,S,Uncharacterized conserved protein,0,0,0,0,0
COG3875,S,Uncharacterized conserved protein,0,2,0,2,4
COG3876,S,Uncharacterized protein conserved in bacteria,0,2,0,1,3
COG3877,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3878,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3879,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3880,S,Uncharacterized protein with conserved CXXC pairs,0,0,0,0,0
COG3881,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3882,Q,Predicted enzyme involved in methoxymalonyl-ACP biosynthesis,1,1,0,0,2
COG3883,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3884,I,Acyl-ACP thioesterase,0,0,0,0,0
COG3885,S,Uncharacterized conserved protein,0,0,0,1,1
COG3886,L,Predicted HKD family nuclease,0,0,0,0,0
COG3887,T,Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain,0,0,0,0,0
COG3888,K,Predicted transcriptional regulator,0,0,0,0,0
COG3889,R,Predicted solute binding protein,0,2,10,4,16
COG3890,I,Phosphomevalonate kinase,0,0,0,0,0
COG3892,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3893,L,Inactivated superfamily I helicase,0,0,0,0,0
COG3894,R,Uncharacterized metal-binding protein,0,0,0,0,0
COG3895,R,Predicted periplasmic protein,0,0,0,0,0
COG3896,V,Chloramphenicol 3-O-phosphotransferase,0,0,0,0,0
COG3897,R,Predicted methyltransferase,0,1,0,0,1
COG3898,S,Uncharacterized membrane-bound protein,0,0,0,0,0
COG3899,R,Predicted ATPase,0,3,11,12,26
COG3900,S,Predicted periplasmic protein,1,0,0,2,3
COG3901,K,Regulator of nitric oxide reductase transcription,0,3,0,0,3
COG3903,R,Predicted ATPase,2,1,0,12,15
COG3904,S,Predicted periplasmic protein,0,0,0,0,0
COG3905,K,Predicted transcriptional regulator,0,0,0,0,0
COG3906,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3907,R,PAP2 (acid phosphatase) superfamily protein,0,2,0,0,2
COG3908,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3909,C,Cytochrome c556,0,1,0,0,1
COG3910,R,Predicted ATPase,0,0,26,1,27
COG3911,R,Predicted ATPase,0,0,0,0,0
COG3913,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3914,O,"Predicted O-linked N-acetylglucosamine transferase, SPINDLY family",0,2,0,0,2
COG3915,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3916,TQ,N-acyl-L-homoserine lactone synthetase,0,0,0,0,0
COG3917,Q,2-hydroxychromene-2-carboxylate isomerase,0,2,0,0,2
COG3918,S,Predicted membrane protein,0,0,0,2,2
COG3919,R,Predicted ATP-grasp enzyme,0,0,15,0,15
COG3920,T,Signal transduction histidine kinase,0,0,16,1,17
COG3921,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3923,L,Primosomal replication protein N'',0,0,0,0,0
COG3924,S,Predicted membrane protein,0,0,0,0,0
COG3925,G,N-terminal domain of the phosphotransferase system fructose-specific component IIB,0,0,0,0,0
COG3926,R,Putative secretion activating protein,0,2,0,0,2
COG3930,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG3931,E,Predicted N-formylglutamate amidohydrolase,0,0,0,0,0
COG3932,R,"Uncharacterized ABC-type transport system, permease components",0,0,0,0,0
COG3933,K,Transcriptional antiterminator,0,0,0,0,0
COG3934,G,Endo-beta-mannanase,0,0,0,0,0
COG3935,L,Putative primosome component and related proteins,0,0,0,0,0
COG3936,G,Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation,0,0,0,0,0
COG3937,S,Uncharacterized conserved protein,0,0,0,0,0
COG3938,E,Proline racemase,0,4,0,0,4
COG3940,R,Predicted beta-xylosidase,0,0,0,0,0
COG3941,R,Mu-like prophage protein,0,0,0,0,0
COG3942,R,Surface antigen,0,0,0,0,0
COG3943,R,Virulence protein,0,0,0,0,0
COG3944,M,Capsular polysaccharide biosynthesis protein,0,0,0,0,0
COG3945,S,Uncharacterized conserved protein,0,0,0,1,1
COG3946,U,"Type IV secretory pathway, VirJ component",0,1,0,0,1
COG3947,T,Response regulator containing CheY-like receiver and SARP domains,0,0,0,1,1
COG3948,R,Phage-related baseplate assembly protein,0,0,0,0,0
COG3949,S,Uncharacterized membrane protein,0,0,0,0,0
COG3950,R,Predicted ATP-binding protein involved in virulence,0,0,0,0,0
COG3951,MNO,Rod binding protein,0,1,0,0,1
COG3952,S,Predicted membrane protein,0,1,0,1,2
COG3953,R,SLT domain proteins,0,0,0,0,0
COG3954,C,Phosphoribulokinase,0,0,0,0,0
COG3955,M,Exopolysaccharide biosynthesis protein,0,0,0,0,0
COG3956,R,Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain,0,1,13,5,19
COG3957,G,Phosphoketolase,1,6,0,7,14
COG3958,G,"Transketolase, C-terminal subunit",0,1,1,3,5
COG3959,G,"Transketolase, N-terminal subunit",0,0,1,5,6
COG3960,R,Glyoxylate carboligase,0,1,12,2,15
COG3961,GHR,Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes,0,0,0,0,0
COG3962,E,Acetolactate synthase,1,2,0,0,3
COG3963,I,Phospholipid N-methyltransferase,0,0,0,2,2
COG3964,R,Predicted amidohydrolase,0,0,0,0,0
COG3965,P,Predicted Co/Zn/Cd cation transporters,2,0,0,0,2
COG3966,M,Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein),0,0,0,0,0
COG3967,M,Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein),0,2,1,1,4
COG3968,R,Uncharacterized protein related to glutamine synthetase,2,0,0,1,3
COG3969,R,Predicted phosphoadenosine phosphosulfate sulfotransferase,0,0,0,0,0
COG3970,R,Fumarylacetoacetate (FAA) hydrolase family protein,0,2,0,0,2
COG3971,Q,2-keto-4-pentenoate hydratase,1,0,35,14,50
COG3972,R,Superfamily I DNA and RNA helicases,0,0,16,0,16
COG3973,R,Superfamily I DNA and RNA helicases,0,0,32,0,32
COG3975,R,Predicted protease with the C-terminal PDZ domain,1,4,0,4,9
COG3976,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG3977,E,Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase,0,0,0,1,1
COG3978,S,"Acetolactate synthase (isozyme II), small (regulatory) subunit",0,0,0,0,0
COG3979,R,Uncharacterized protein contain chitin-binding domain type 3,0,0,0,0,0
COG3980,M,"Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase",0,0,0,0,0
COG3981,R,Predicted acetyltransferase,0,0,28,2,30
COG4001,R,Predicted metal-binding protein,0,0,0,0,0
COG4002,R,Predicted phosphotransacetylase,0,0,0,0,0
COG4003,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4004,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4006,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4007,R,"Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase",0,0,0,0,0
COG4008,K,Predicted metal-binding transcription factor,0,0,0,0,0
COG4009,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4010,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4012,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4013,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4014,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4015,R,Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family,0,0,0,0,0
COG4016,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4017,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4018,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4019,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4020,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4021,S,Uncharacterized conserved protein,1,0,0,0,1
COG4022,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4023,U,Preprotein translocase subunit Sec61beta,0,0,0,0,0
COG4024,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4025,S,Predicted membrane protein,0,0,0,0,0
COG4026,R,"Uncharacterized protein containing TOPRIM domain, potential nuclease",0,0,0,0,0
COG4027,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4028,R,Predicted P-loop ATPase/GTPase,0,0,0,0,0
COG4029,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4030,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4031,R,Predicted metal-binding protein,0,0,0,0,0
COG4032,R,Predicted thiamine-pyrophosphate-binding protein,0,2,0,3,5
COG4033,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4034,S,Uncharacterized protein conserved in archaea,4,0,0,0,4
COG4035,S,Predicted membrane protein,0,0,0,0,0
COG4036,S,Predicted membrane protein,0,0,0,0,0
COG4037,S,Predicted membrane protein,0,0,0,0,0
COG4038,S,Predicted membrane protein,0,0,0,0,0
COG4039,S,Predicted membrane protein,0,0,0,0,0
COG4040,S,Predicted membrane protein,0,0,0,0,0
COG4041,S,Predicted membrane protein,0,0,0,0,0
COG4042,S,Predicted membrane protein,0,0,0,0,0
COG4043,S,Uncharacterized conserved protein,0,0,0,0,0
COG4044,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4046,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4047,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4048,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4049,R,Uncharacterized protein containing archaeal-type C2H2 Zn-finger,0,0,0,0,0
COG4050,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4051,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4052,R,Uncharacterized protein related to methyl coenzyme M reductase subunit C,0,0,0,0,0
COG4053,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4054,H,"Methyl coenzyme M reductase, beta subunit",0,0,0,0,0
COG4055,H,"Methyl coenzyme M reductase, subunit D",0,0,0,0,0
COG4056,H,"Methyl coenzyme M reductase, subunit C",0,0,0,0,0
COG4057,H,"Methyl coenzyme M reductase, gamma subunit",0,0,0,0,0
COG4058,H,"Methyl coenzyme M reductase, alpha subunit",0,0,0,0,0
COG4059,H,"Tetrahydromethanopterin S-methyltransferase, subunit E",0,0,0,0,0
COG4060,H,"Tetrahydromethanopterin S-methyltransferase, subunit D",0,0,0,0,0
COG4061,H,"Tetrahydromethanopterin S-methyltransferase, subunit C",0,0,0,0,0
COG4062,H,"Tetrahydromethanopterin S-methyltransferase, subunit B",0,0,0,0,0
COG4063,H,"Tetrahydromethanopterin S-methyltransferase, subunit A",0,0,0,2,2
COG4064,H,"Tetrahydromethanopterin S-methyltransferase, subunit G",0,0,0,0,0
COG4065,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4066,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4067,O,Uncharacterized protein conserved in archaea,0,3,0,0,3
COG4068,S,Uncharacterized protein containing a Zn-ribbon,0,0,0,0,0
COG4069,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4070,O,"Predicted peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family",0,0,0,0,0
COG4071,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4072,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4073,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4074,C,"H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase",0,0,0,0,0
COG4075,S,"Uncharacterized conserved protein, homolog of nitrogen regulatory protein PII",0,0,0,0,0
COG4076,R,Predicted RNA methylase,0,0,0,0,0
COG4077,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4078,S,Predicted membrane protein,0,0,0,0,0
COG4079,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4080,L,RecB-family nuclease,0,0,0,0,0
COG4081,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4083,S,Predicted membrane protein,0,0,0,0,0
COG4084,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4085,R,"Predicted RNA-binding protein, contains TRAM domain",0,0,0,0,0
COG4086,S,Predicted secreted protein,0,0,0,0,0
COG4087,R,Soluble P-type ATPase,0,0,0,0,0
COG4088,F,Predicted nucleotide kinase,0,0,0,0,0
COG4089,S,Predicted membrane protein,0,0,0,0,0
COG4090,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4091,E,Predicted homoserine dehydrogenase,0,0,0,0,0
COG4092,M,Predicted glycosyltransferase involved in capsule biosynthesis,0,0,0,0,0
COG4093,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4094,S,Predicted membrane protein,0,0,0,0,0
COG4095,S,Uncharacterized conserved protein,0,0,0,1,1
COG4096,V,"Type I site-specific restriction-modification system, R (restriction) subunit and related helicases",0,0,0,5,5
COG4097,P,Predicted ferric reductase,0,0,0,0,0
COG4098,L,Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein),0,0,0,0,0
COG4099,R,Predicted peptidase,0,0,0,0,0
COG4100,P,Cystathionine beta-lyase family protein involved in aluminum resistance,0,0,0,0,0
COG4101,G,Predicted mannose-6-phosphate isomerase,0,0,28,13,41
COG4102,S,Uncharacterized protein conserved in bacteria,0,1,0,7,8
COG4103,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4104,S,Uncharacterized conserved protein,0,1,0,2,3
COG4105,R,DNA uptake lipoprotein,0,2,0,3,5
COG4106,R,Trans-aconitate methyltransferase,0,4,6,1,11
COG4107,P,"ABC-type phosphonate transport system, ATPase component",0,0,0,0,0
COG4108,J,Peptide chain release factor RF-3,2,2,0,0,4
COG4109,K,Predicted transcriptional regulator containing CBS domains,0,0,0,0,0
COG4110,R,Uncharacterized protein involved in stress response,0,0,0,0,0
COG4111,R,Uncharacterized conserved protein,0,0,1,0,1
COG4112,R,Predicted phosphoesterase (MutT family),0,0,0,1,1
COG4113,R,"Predicted nucleic acid-binding protein, contains PIN domain",0,0,0,0,0
COG4114,R,Uncharacterized Fe-S protein,0,0,0,0,0
COG4115,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4116,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4117,C,Thiosulfate reductase cytochrome B subunit (membrane anchoring protein),0,2,9,1,12
COG4118,D,Antitoxin of toxin-antitoxin stability system,0,1,0,0,1
COG4119,LR,Predicted NTP pyrophosphohydrolase,0,0,0,1,1
COG4120,R,"ABC-type uncharacterized transport system, permease component",0,1,15,0,16
COG4121,S,Uncharacterized conserved protein,0,0,0,0,0
COG4122,R,Predicted O-methyltransferase,0,1,14,17,32
COG4123,R,Predicted O-methyltransferase,0,1,0,1,2
COG4124,G,Beta-mannanase,0,0,0,3,3
COG4125,S,Predicted membrane protein,0,1,16,0,17
COG4126,E,Hydantoin racemase,0,2,20,1,23
COG4127,S,Uncharacterized conserved protein,0,0,0,0,0
COG4128,R,Zonula occludens toxin,0,0,0,0,0
COG4129,S,Predicted membrane protein,0,0,15,1,16
COG4130,G,Predicted sugar epimerase,0,1,0,0,1
COG4132,R,"ABC-type uncharacterized transport system, permease component",0,2,19,0,21
COG4133,O,"ABC-type transport system involved in cytochrome c biogenesis, ATPase component",0,2,0,1,3
COG4134,R,"ABC-type uncharacterized transport system, periplasmic component",0,0,0,0,0
COG4135,R,"ABC-type uncharacterized transport system, permease component",0,0,0,0,0
COG4136,R,"ABC-type uncharacterized transport system, ATPase component",0,0,0,0,0
COG4137,R,"ABC-type uncharacterized transport system, permease component",0,3,0,0,3
COG4138,H,"ABC-type cobalamin transport system, ATPase component",0,0,0,0,0
COG4139,H,"ABC-type cobalamin transport system, permease component",0,0,0,0,0
COG4143,H,"ABC-type thiamine transport system, periplasmic component",0,0,0,0,0
COG4145,H,Na+/panthothenate symporter,0,0,0,0,0
COG4146,R,Predicted symporter,0,0,0,0,0
COG4147,R,Predicted symporter,0,5,39,3,47
COG4148,P,"ABC-type molybdate transport system, ATPase component",0,4,0,0,4
COG4149,P,"ABC-type molybdate transport system, permease component",0,3,13,2,18
COG4150,P,"ABC-type sulfate transport system, periplasmic component",0,0,0,0,0
COG4152,R,"ABC-type uncharacterized transport system, ATPase component",1,1,21,1,24
COG4154,G,Fucose dissimilation pathway protein FucU,0,0,0,0,0
COG4158,R,"Predicted ABC-type sugar transport system, permease component",0,2,1,0,3
COG4160,E,"ABC-type arginine/histidine transport system, permease component",0,6,0,0,6
COG4161,E,"ABC-type arginine transport system, ATPase component",0,0,0,0,0
COG4166,E,"ABC-type oligopeptide transport system, periplasmic component",0,9,16,15,40
COG4167,V,"ABC-type antimicrobial peptide transport system, ATPase component",0,0,0,0,0
COG4168,V,"ABC-type antimicrobial peptide transport system, permease component",0,0,0,0,0
COG4170,V,"ABC-type antimicrobial peptide transport system, ATPase component",0,0,0,0,0
COG4171,V,"ABC-type antimicrobial peptide transport system, permease component",0,0,0,0,0
COG4172,R,"ABC-type uncharacterized transport system, duplicated ATPase component",0,5,0,5,10
COG4174,R,"ABC-type uncharacterized transport system, permease component",0,6,0,1,7
COG4175,E,"ABC-type proline/glycine betaine transport system, ATPase component",0,3,0,0,3
COG4176,E,"ABC-type proline/glycine betaine transport system, permease component",0,5,0,0,5
COG4177,E,"ABC-type branched-chain amino acid transport system, permease component",1,7,16,8,32
COG4178,R,"ABC-type uncharacterized transport system, permease and ATPase components",0,3,0,1,4
COG4181,Q,"Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component",0,1,0,1,2
COG4185,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4186,R,Predicted phosphoesterase or phosphohydrolase,0,2,0,1,3
COG4187,E,Arginine degradation protein (predicted deacylase),0,0,0,0,0
COG4188,R,Predicted dienelactone hydrolase,0,0,0,0,0
COG4189,K,Predicted transcriptional regulator,0,0,0,0,0
COG4190,K,Predicted transcriptional regulator,0,0,0,0,0
COG4191,T,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,6,24,2,24,56
COG4192,T,Signal transduction histidine kinase regulating phosphoglycerate transport system,0,0,0,0,0
COG4193,G,Beta- N-acetylglucosaminidase,0,0,0,0,0
COG4194,R,Predicted membrane protein,0,0,0,0,0
COG4195,R,Phage-related replication protein,0,0,0,0,0
COG4196,S,Uncharacterized protein conserved in bacteria,0,2,0,1,3
COG4197,S,"Uncharacterized protein conserved in bacteria, prophage-related",0,2,0,0,2
COG4198,S,Uncharacterized conserved protein,0,1,0,0,1
COG4199,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4200,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4206,H,Outer membrane cobalamin receptor protein,1,8,0,9,18
COG4208,P,"ABC-type sulfate transport system, permease component",0,1,0,1,2
COG4209,G,"ABC-type polysaccharide transport system, permease component",0,0,0,0,0
COG4211,G,"ABC-type glucose/galactose transport system, permease component",0,0,0,0,0
COG4213,G,"ABC-type xylose transport system, periplasmic component",0,0,13,3,16
COG4214,G,"ABC-type xylose transport system, permease component",0,0,26,3,29
COG4215,E,"ABC-type arginine transport system, permease component",0,8,0,0,8
COG4218,H,"Tetrahydromethanopterin S-methyltransferase, subunit F",0,0,0,0,0
COG4219,KT,"Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component",1,1,0,1,3
COG4220,L,"Phage DNA packaging protein, Nu1 subunit of terminase",0,0,0,0,0
COG4221,R,Short-chain alcohol dehydrogenase of unknown specificity,0,19,61,47,127
COG4222,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4223,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4224,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4225,R,"Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins",0,0,0,0,0
COG4226,S,Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters,0,0,0,0,0
COG4227,L,Antirestriction protein,0,3,0,0,3
COG4228,R,Mu-like prophage DNA circulation protein,0,1,0,0,1
COG4229,C,Predicted enolase-phosphatase,0,3,0,2,5
COG4230,C,Delta 1-pyrroline-5-carboxylate dehydrogenase,0,2,1,0,3
COG4231,C,"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits",0,1,0,4,5
COG4232,OC,Thiol:disulfide interchange protein,0,4,0,1,5
COG4233,OC,Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis,0,0,0,0,0
COG4235,O,Cytochrome c biogenesis factor,0,4,0,0,4
COG4237,C,Hydrogenase 4 membrane component (E),0,0,0,0,0
COG4238,M,Murein lipoprotein,0,0,0,0,0
COG4239,R,"ABC-type uncharacterized transport system, permease component",0,3,0,5,8
COG4240,R,Predicted kinase,0,0,0,0,0
COG4241,S,Predicted membrane protein,0,0,0,0,0
COG4242,QP,Cyanophycinase and related exopeptidases,0,1,13,4,18
COG4243,S,Predicted membrane protein,0,1,16,0,17
COG4244,S,Predicted membrane protein,0,0,0,0,0
COG4245,R,"Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain",0,0,0,0,0
COG4246,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4247,I,3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase),0,0,0,1,1
COG4248,R,Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains,0,0,0,0,0
COG4249,R,Uncharacterized protein containing caspase domain,0,0,0,1,1
COG4250,T,Predicted sensor protein/domain,0,0,0,0,0
COG4251,T,Bacteriophytochrome (light-regulated signal transduction histidine kinase),0,0,0,6,6
COG4252,T,Predicted transmembrane sensor domain,0,0,0,0,0
COG4253,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4254,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4255,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4256,P,Hemin uptake protein,0,0,0,0,0
COG4257,V,Streptogramin lyase,0,0,1,7,8
COG4258,R,Predicted exporter,0,1,0,0,1
COG4259,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4260,S,Putative virion core protein (lumpy skin disease virus),0,1,0,4,5
COG4261,R,Predicted acyltransferase,0,2,0,1,3
COG4262,R,Predicted spermidine synthase with an N-terminal membrane domain,0,0,0,1,1
COG4263,C,Nitrous oxide reductase,0,1,0,2,3
COG4264,Q,Siderophore synthetase component,0,5,11,1,17
COG4266,F,Allantoicase,0,3,0,4,7
COG4267,S,Predicted membrane protein,0,0,0,0,0
COG4268,V,McrBC 5-methylcytosine restriction system component,0,0,0,0,0
COG4269,S,Predicted membrane protein,0,0,0,0,0
COG4270,S,Predicted membrane protein,0,0,14,0,14
COG4271,K,Predicted nucleotide-binding protein containing TIR -like domain,0,0,0,1,1
COG4272,S,Predicted membrane protein,0,0,0,0,0
COG4273,S,Uncharacterized conserved protein,0,1,0,0,1
COG4274,S,Uncharacterized conserved protein,0,1,0,5,6
COG4275,S,Uncharacterized conserved protein,0,1,0,4,5
COG4276,S,Uncharacterized conserved protein,0,0,10,7,17
COG4277,R,Predicted DNA-binding protein with the Helix-hairpin-helix motif,0,0,0,0,0
COG4278,S,Uncharacterized conserved protein,0,0,0,0,0
COG4279,S,Uncharacterized conserved protein,0,0,0,0,0
COG4280,S,Predicted membrane protein,0,0,0,0,0
COG4281,I,Acyl-CoA-binding protein,0,0,0,0,0
COG4282,G,"Protein involved in beta-1,3-glucan synthesis",0,0,0,0,0
COG4283,S,Uncharacterized conserved protein,0,0,0,0,0
COG4284,G,UDP-glucose pyrophosphorylase,0,0,0,0,0
COG4285,S,Uncharacterized conserved protein,0,0,0,0,0
COG4286,S,Uncharacterized conserved protein related to MYG1 family,0,0,0,0,0
COG4287,R,PhoPQ-activated pathogenicity-related protein,0,1,0,0,1
COG4288,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4289,S,Uncharacterized protein conserved in bacteria,8,0,0,2,10
COG4290,F,Guanyl-specific ribonuclease Sa,0,0,0,0,0
COG4291,S,Predicted membrane protein,0,2,0,0,2
COG4292,S,Predicted membrane protein,0,0,1,3,4
COG4293,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG4294,L,UV damage repair endonuclease,0,0,0,0,0
COG4295,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4296,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4297,S,Uncharacterized protein containing double-stranded beta helix domain,0,0,0,1,1
COG4298,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4299,S,Uncharacterized conserved protein,1,3,0,1,5
COG4300,P,"Predicted permease, cadmium resistance protein",0,0,1,0,1
COG4301,S,Uncharacterized conserved protein,1,4,0,3,8
COG4302,E,"Ethanolamine ammonia-lyase, small subunit",0,1,0,0,1
COG4303,E,"Ethanolamine ammonia-lyase, large subunit",0,2,0,0,2
COG4304,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4305,G,Endoglucanase C-terminal domain/subunit and related proteins,0,0,0,0,0
COG4306,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4307,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG4308,Q,"Limonene-1,2-epoxide hydrolase",0,0,0,0,0
COG4309,S,Uncharacterized conserved protein,0,0,16,1,17
COG4310,R,Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain,0,0,0,0,0
COG4311,E,Sarcosine oxidase delta subunit,0,3,13,1,17
COG4312,S,Uncharacterized protein conserved in bacteria,4,1,3,10,18
COG4313,C,Protein involved in meta-pathway of phenol degradation,0,3,0,0,3
COG4314,C,Predicted lipoprotein involved in nitrous oxide reduction,0,1,0,0,1
COG4315,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG4316,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4317,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4318,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4319,S,Ketosteroid isomerase homolog,0,1,0,6,7
COG4320,S,Uncharacterized protein conserved in bacteria,0,0,1,2,3
COG4321,R,Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis,0,1,0,1,2
COG4322,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4323,S,Predicted membrane protein,0,1,0,0,1
COG4324,R,Predicted aminopeptidase,0,1,0,0,1
COG4325,S,Predicted membrane protein,0,0,0,1,1
COG4326,R,Sporulation control protein,0,0,0,0,0
COG4327,S,Predicted membrane protein,0,0,0,0,0
COG4328,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4329,S,Predicted membrane protein,0,0,0,0,0
COG4330,S,Predicted membrane protein,0,0,0,1,1
COG4331,S,Predicted membrane protein,0,0,15,3,18
COG4332,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4333,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG4334,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4335,L,DNA alkylation repair enzyme,0,1,15,0,16
COG4336,S,Uncharacterized conserved protein,4,1,15,1,21
COG4337,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4338,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4339,S,Uncharacterized protein conserved in bacteria,0,0,15,1,16
COG4340,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4341,R,Predicted HD phosphohydrolase,0,1,0,1,2
COG4342,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4343,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4344,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4345,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4346,O,Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase,0,0,0,0,0
COG4347,S,Predicted membrane protein,0,0,0,0,0
COG4352,J,Ribosomal protein L13E,0,0,0,0,0
COG4353,S,Uncharacterized conserved protein,0,0,0,0,0
COG4354,G,Predicted bile acid beta-glucosidase,0,0,0,0,0
COG4357,S,Uncharacterized conserved protein,0,0,13,1,14
COG4359,E,"Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling",0,0,0,0,0
COG4360,F,"ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II)",0,0,0,0,0
COG4362,PE,"Nitric oxide synthase, oxygenase domain",0,0,0,0,0
COG4365,S,Uncharacterized protein conserved in bacteria,0,1,0,4,5
COG4367,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4370,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4371,S,Predicted membrane protein,0,0,0,0,0
COG4372,S,Uncharacterized protein conserved in bacteria with the myosin-like domain,0,0,0,0,0
COG4373,R,Mu-like prophage FluMu protein gp28,0,0,0,0,0
COG4374,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4377,S,Predicted membrane protein,0,0,0,0,0
COG4378,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4379,R,Mu-like prophage tail protein gpP,0,2,0,0,2
COG4380,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4381,S,Mu-like prophage protein gp46,0,0,0,0,0
COG4382,S,Mu-like prophage protein gp16,0,0,0,0,0
COG4383,S,Mu-like prophage protein gp29,0,0,0,0,0
COG4384,S,Mu-like prophage protein gp45,0,1,0,0,1
COG4385,R,Bacteriophage P2-related tail formation protein,0,0,0,0,0
COG4386,R,Mu-like prophage tail sheath protein gpL,0,2,0,0,2
COG4387,S,Mu-like prophage protein gp36,0,0,0,1,1
COG4388,R,Mu-like prophage I protein,0,0,0,0,0
COG4389,L,Site-specific recombinase,0,0,0,0,0
COG4390,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4391,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4392,S,Predicted membrane protein,0,0,0,0,0
COG4393,S,Predicted membrane protein,0,0,0,0,0
COG4394,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG4395,S,Uncharacterized protein conserved in bacteria,1,1,0,0,2
COG4396,R,Mu-like prophage host-nuclease inhibitor protein Gam,0,0,0,0,0
COG4397,R,Mu-like prophage major head subunit gpT,0,0,0,0,0
COG4398,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4399,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4401,E,Chorismate mutase,0,0,0,0,0
COG4402,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG4403,V,Lantibiotic modifying enzyme,0,0,0,1,1
COG4405,S,Uncharacterized protein conserved in bacteria,0,0,14,0,14
COG4408,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4409,G,Neuraminidase (sialidase),0,0,0,0,0
COG4412,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4413,E,Urea transporter,0,1,0,0,1
COG4416,R,Mu-like prophage protein Com,0,0,0,0,0
COG4420,S,Predicted membrane protein,0,2,11,4,17
COG4421,G,Capsular polysaccharide biosynthesis protein,0,0,0,0,0
COG4422,S,Bacteriophage protein gp37,0,1,0,0,1
COG4423,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4424,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4425,S,Predicted membrane protein,0,0,0,0,0
COG4427,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4430,S,Uncharacterized protein conserved in bacteria,3,0,17,7,27
COG4443,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4445,FJ,Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA,0,0,0,0,0
COG4446,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4447,R,Uncharacterized protein related to plant photosystem II stability/assembly factor,0,7,0,5,12
COG4448,E,L-asparaginase II,0,1,42,2,45
COG4449,R,Predicted protease of the Abi (CAAX) family,0,0,0,0,0
COG4451,C,Ribulose bisphosphate carboxylase small subunit,0,0,0,0,0
COG4452,V,Inner membrane protein involved in colicin E2 resistance,4,1,0,1,6
COG4453,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4454,P,Uncharacterized copper-binding protein,0,1,0,0,1
COG4455,R,Protein of avirulence locus involved in temperature-dependent protein secretion,0,0,0,0,0
COG4456,S,Virulence-associated protein and related proteins,0,0,0,0,0
COG4457,S,"Uncharacterized protein conserved in bacteria, putative virulence factor",0,12,0,0,12
COG4458,S,"Uncharacterized protein conserved in bacteria, putative virulence factor",0,4,0,0,4
COG4459,C,"Periplasmic nitrate reductase system, NapE component",0,0,0,0,0
COG4460,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4461,S,"Uncharacterized protein conserved in bacteria, putative lipoprotein",0,1,0,0,1
COG4463,K,Transcriptional repressor of class III stress genes,0,0,0,0,0
COG4464,GM,Capsular polysaccharide biosynthesis protein,0,0,0,0,0
COG4465,K,Pleiotropic transcriptional repressor,0,0,0,0,0
COG4466,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4467,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4468,G,Galactose-1-phosphate uridyltransferase,0,0,0,0,0
COG4469,R,Competence protein,0,0,0,0,0
COG4470,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4471,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4472,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4473,U,"Predicted ABC-type exoprotein transport system, permease component",0,0,0,0,0
COG4474,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4475,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4476,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4477,D,Negative regulator of septation ring formation,0,0,0,0,0
COG4478,S,Predicted membrane protein,0,0,15,0,15
COG4479,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4481,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4483,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4485,S,Predicted membrane protein,0,0,0,0,0
COG4487,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG4492,R,ACT domain-containing protein,0,0,0,0,0
COG4493,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4495,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4496,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4499,S,Predicted membrane protein,0,0,0,0,0
COG4502,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4506,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4508,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4509,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4512,OTK,Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide,0,0,0,0,0
COG4517,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4518,S,Mu-like prophage FluMu protein gp41,0,0,0,0,0
COG4519,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4520,M,Surface antigen,0,0,0,0,0
COG4521,P,"ABC-type taurine transport system, periplasmic component",0,3,0,0,3
COG4525,P,"ABC-type taurine transport system, ATPase component",0,1,0,0,1
COG4529,S,Uncharacterized protein conserved in bacteria,0,1,26,1,28
COG4530,S,Uncharacterized protein conserved in bacteria,0,0,0,2,2
COG4531,P,"ABC-type Zn2+ transport system, periplasmic component/surface adhesin",0,2,0,1,3
COG4533,R,"ABC-type uncharacterized transport system, periplasmic component",0,0,0,1,1
COG4535,P,Putative Mg2+ and Co2+ transporter CorC,0,2,0,0,2
COG4536,P,Putative Mg2+ and Co2+ transporter CorB,0,2,4,2,8
COG4537,U,Competence protein ComGC,0,0,0,0,0
COG4538,S,Uncharacterized conserved protein,0,0,0,0,0
COG4539,S,Predicted membrane protein,0,0,0,0,0
COG4540,R,Phage P2 baseplate assembly protein gpV,0,0,0,0,0
COG4541,S,Predicted membrane protein,0,0,0,0,0
COG4542,Q,"Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase",0,0,0,0,0
COG4544,S,Uncharacterized conserved protein,0,1,0,0,1
COG4545,O,Glutaredoxin-related protein,0,0,0,0,0
COG4547,H,"Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)",0,0,0,0,0
COG4548,P,Nitric oxide reductase activation protein,0,0,0,1,1
COG4549,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4550,S,Predicted membrane protein,0,0,0,0,0
COG4551,R,Predicted protein tyrosine phosphatase,0,0,0,0,0
COG4552,R,Predicted acetyltransferase involved in intracellular survival and related acetyltransferases,0,0,22,0,22
COG4553,I,Poly-beta-hydroxyalkanoate depolymerase,0,1,0,1,2
COG4555,CP,"ABC-type Na+ transport system, ATPase component",0,0,0,1,1
COG4558,P,"ABC-type hemin transport system, periplasmic component",0,3,0,1,4
COG4559,P,"ABC-type hemin transport system, ATPase component",0,0,0,0,0
COG4564,T,Signal transduction histidine kinase,0,4,3,2,9
COG4565,KT,Response regulator of citrate/malate metabolism,0,0,70,3,73
COG4566,T,Response regulator,1,4,0,11,16
COG4567,TK,Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain,0,2,0,0,2
COG4568,K,Transcriptional antiterminator,0,0,0,0,0
COG4569,Q,Acetaldehyde dehydrogenase (acetylating),0,0,24,1,25
COG4570,L,Holliday junction resolvase,0,0,0,0,0
COG4571,M,Outer membrane protease,0,0,0,0,0
COG4572,R,Putative cation transport regulator,0,0,0,1,1
COG4573,G,Predicted tagatose 6-phosphate kinase,0,0,0,0,0
COG4574,R,Serine protease inhibitor ecotin,0,0,0,0,0
COG4575,S,Uncharacterized conserved protein,0,0,0,1,1
COG4576,QC,Carbon dioxide concentrating mechanism/carboxysome shell protein,0,5,0,1,6
COG4577,QC,Carbon dioxide concentrating mechanism/carboxysome shell protein,0,2,0,2,4
COG4578,K,Glucitol operon activator,0,0,0,0,0
COG4579,T,Isocitrate dehydrogenase kinase/phosphatase,4,3,1,9,17
COG4580,G,Maltoporin (phage lambda and maltose receptor),0,6,0,1,7
COG4581,L,Superfamily II RNA helicase,0,0,35,14,49
COG4582,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4583,E,Sarcosine oxidase gamma subunit,0,1,13,1,15
COG4584,L,Transposase and inactivated derivatives,0,0,8,1,9
COG4585,T,Signal transduction histidine kinase,2,6,203,31,242
COG4586,R,"ABC-type uncharacterized transport system, ATPase component",0,0,0,5,5
COG4587,R,"ABC-type uncharacterized transport system, permease component",0,0,0,2,2
COG4588,R,"Accessory colonization factor AcfC, contains ABC-type periplasmic domain",0,0,0,0,0
COG4589,R,Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase,0,3,0,5,8
COG4590,R,"ABC-type uncharacterized transport system, permease component",0,2,0,2,4
COG4591,M,"ABC-type transport system, involved in lipoprotein release, permease component",0,40,16,31,87
COG4592,P,"ABC-type Fe2+-enterobactin transport system, periplasmic component",0,0,0,0,0
COG4594,P,"ABC-type Fe3+-citrate transport system, periplasmic component",0,0,0,0,0
COG4597,E,"ABC-type amino acid transport system, permease component",0,2,0,2,4
COG4598,E,"ABC-type histidine transport system, ATPase component",0,10,0,0,10
COG4603,R,"ABC-type uncharacterized transport system, permease component",0,6,16,5,27
COG4604,P,"ABC-type enterochelin transport system, ATPase component",0,0,13,1,14
COG4605,P,"ABC-type enterochelin transport system, permease component",0,0,13,1,14
COG4606,P,"ABC-type enterochelin transport system, permease component",0,0,13,2,15
COG4607,P,"ABC-type enterochelin transport system, periplasmic component",0,0,12,1,13
COG4608,E,"ABC-type oligopeptide transport system, ATPase component",0,4,33,5,42
COG4615,QP,"ABC-type siderophore export system, fused ATPase and permease components",0,4,0,1,5
COG4618,R,"ABC-type protease/lipase transport system, ATPase and permease components",0,6,0,0,6
COG4619,R,"ABC-type uncharacterized transport system, ATPase component",0,0,0,0,0
COG4623,M,Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein,1,6,0,5,12
COG4624,R,"Iron only hydrogenase large subunit, C-terminal domain",0,0,0,0,0
COG4625,S,Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain,0,4,0,0,4
COG4626,R,"Phage terminase-like protein, large subunit",0,8,20,9,37
COG4627,S,Uncharacterized protein conserved in bacteria,0,0,2,15,17
COG4628,S,Uncharacterized conserved protein,0,1,0,0,1
COG4630,F,"Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A",0,3,31,1,35
COG4631,F,"Xanthine dehydrogenase, molybdopterin-binding subunit B",1,4,38,5,48
COG4632,G,Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase,0,0,0,0,0
COG4633,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4634,S,Uncharacterized protein conserved in bacteria,0,0,0,5,5
COG4635,CH,Flavodoxin,0,0,0,1,1
COG4636,S,Uncharacterized protein conserved in cyanobacteria,1,4,0,0,5
COG4637,R,Predicted ATPase,0,2,0,0,2
COG4638,PR,"Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit",0,7,41,7,55
COG4639,R,Predicted kinase,0,0,0,0,0
COG4640,S,Predicted membrane protein,0,0,0,0,0
COG4641,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4642,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4643,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4644,L,"Transposase and inactivated derivatives, TnpA family",0,0,2,14,16
COG4645,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4646,KL,DNA methylase,0,0,0,2,2
COG4647,Q,"Acetone carboxylase, gamma subunit",0,0,0,0,0
COG4648,S,Predicted membrane protein,0,1,0,0,1
COG4649,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4650,KT,Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain,0,0,0,0,0
COG4651,P,"Kef-type K+ transport system, predicted NAD-binding component",0,2,0,6,8
COG4652,S,Uncharacterized protein conserved in bacteria,0,0,15,0,15
COG4653,R,Predicted phage phi-C31 gp36 major capsid-like protein,7,2,0,0,9
COG4654,C,Cytochrome c551/c552,0,0,0,0,0
COG4655,S,Predicted membrane protein,0,1,0,0,1
COG4656,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfC",0,0,0,0,0
COG4657,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfA",0,2,0,0,2
COG4658,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfD",0,1,0,0,1
COG4659,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfG",0,1,0,1,2
COG4660,C,"Predicted NADH:ubiquinone oxidoreductase, subunit RnfE",0,0,0,0,0
COG4662,H,"ABC-type tungstate transport system, periplasmic component",0,0,0,0,0
COG4663,Q,"TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component",0,0,0,1,1
COG4664,Q,"TRAP-type mannitol/chloroaromatic compound transport system, large permease component",0,0,0,6,6
COG4665,Q,"TRAP-type mannitol/chloroaromatic compound transport system, small permease component",0,0,0,1,1
COG4666,R,"TRAP-type uncharacterized transport system, fused permease components",0,0,0,1,1
COG4667,R,Predicted esterase of the alpha-beta hydrolase superfamily,0,0,0,0,0
COG4668,G,"Mannitol/fructose-specific phosphotransferase system, IIA domain",0,1,0,0,1
COG4669,U,"Type III secretory pathway, lipoprotein EscJ",0,0,0,0,0
COG4670,I,Acyl CoA:acetate/3-ketoacid CoA transferase,0,0,0,5,5
COG4671,R,Predicted glycosyl transferase,0,0,12,1,13
COG4672,S,Phage-related protein,0,0,0,0,0
COG4674,R,"Uncharacterized ABC-type transport system, ATPase component",0,0,0,0,0
COG4675,S,Microcystin-dependent protein,0,4,0,2,6
COG4676,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG4677,G,Pectin methylesterase,0,0,0,1,1
COG4678,G,Muramidase (phage lambda lysozyme),0,1,0,0,1
COG4679,S,Phage-related protein,0,0,0,0,0
COG4680,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4681,S,Uncharacterized protein conserved in bacteria,0,2,15,1,18
COG4682,S,Predicted membrane protein,0,0,0,0,0
COG4683,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4684,S,Predicted membrane protein,0,0,0,0,0
COG4685,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG4687,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4688,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4689,Q,Acetoacetate decarboxylase,0,0,0,0,0
COG4690,E,Dipeptidase,0,0,0,0,0
COG4691,R,Plasmid stability protein,0,1,0,0,1
COG4692,G,Predicted neuraminidase (sialidase),0,0,0,0,0
COG4693,Q,"Oxidoreductase (NAD-binding), involved in siderophore biosynthesis",0,0,0,0,0
COG4694,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4695,S,Phage-related protein,0,3,3,3,9
COG4696,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4697,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4698,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4699,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4700,S,Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats,0,0,0,0,0
COG4701,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4702,S,Uncharacterized conserved protein,0,0,0,0,0
COG4703,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4704,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4705,S,Uncharacterized membrane-anchored protein conserved in bacteria,1,1,0,3,5
COG4706,I,Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase,2,1,0,0,3
COG4707,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4708,S,Predicted membrane protein,0,0,0,0,0
COG4709,S,Predicted membrane protein,0,0,7,0,7
COG4710,R,Predicted DNA-binding protein with an HTH domain,0,0,0,0,0
COG4711,S,Predicted membrane protein,0,0,0,0,0
COG4712,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4713,S,Predicted membrane protein,0,0,0,0,0
COG4714,S,Uncharacterized membrane-anchored protein conserved in bacteria,0,0,0,1,1
COG4715,S,Uncharacterized conserved protein,0,0,0,0,0
COG4716,S,Myosin-crossreactive antigen,0,0,0,0,0
COG4717,S,Uncharacterized conserved protein,0,0,0,0,0
COG4718,S,Phage-related protein,0,0,0,0,0
COG4719,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4720,S,Predicted membrane protein,0,0,0,0,0
COG4721,S,Predicted membrane protein,0,0,14,0,14
COG4722,S,Phage-related protein,0,0,0,0,0
COG4723,S,"Phage-related protein, tail component",0,0,0,8,8
COG4724,G,Endo-beta-N-acetylglucosaminidase D,0,0,0,0,0
COG4725,TK,"Transcriptional activator, adenine-specific DNA methyltransferase",0,0,0,0,0
COG4726,NU,Tfp pilus assembly protein PilX,0,1,0,0,1
COG4727,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4728,S,Uncharacterized protein conserved in bacteria,0,1,14,0,15
COG4729,S,Uncharacterized conserved protein,0,0,0,0,0
COG4731,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4732,S,Predicted membrane protein,0,0,0,0,0
COG4733,S,"Phage-related protein, tail component",0,0,0,1,1
COG4734,R,Antirestriction protein,0,0,0,0,0
COG4735,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4736,O,"Cbb3-type cytochrome oxidase, subunit 3",0,0,0,0,0
COG4737,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG4738,K,Predicted transcriptional regulator,0,0,0,0,0
COG4739,S,Uncharacterized protein containing a ferredoxin domain,0,0,0,0,0
COG4740,R,Predicted metalloprotease,0,0,0,0,0
COG4741,F,Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase,0,0,0,0,0
COG4742,K,Predicted transcriptional regulator,0,0,0,0,0
COG4743,S,Predicted membrane protein,0,0,0,0,0
COG4744,S,Uncharacterized conserved protein,0,0,0,0,0
COG4745,O,Predicted membrane-bound mannosyltransferase,0,0,0,4,4
COG4746,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4747,R,ACT domain-containing protein,0,0,0,0,0
COG4748,S,Uncharacterized conserved protein,0,0,0,0,0
COG4749,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4750,M,CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes,0,0,0,0,0
COG4752,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4753,T,Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain,1,4,0,10,15
COG4754,S,Uncharacterized conserved protein,0,0,0,0,0
COG4755,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4756,R,Predicted cation transporter,0,0,0,0,0
COG4757,R,Predicted alpha/beta hydrolase,0,0,0,0,0
COG4758,S,Predicted membrane protein,0,0,0,0,0
COG4759,O,Uncharacterized protein conserved in bacteria containing thioredoxin-like domain,0,0,0,0,0
COG4760,S,Predicted membrane protein,0,0,15,1,16
COG4762,S,Uncharacterized protein conserved in bacteria,0,2,15,0,17
COG4763,S,Predicted membrane protein,0,0,0,0,0
COG4764,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4765,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4766,E,Ethanolamine utilization protein,0,0,0,0,0
COG4767,V,Glycopeptide antibiotics resistance protein,0,0,19,0,19
COG4768,R,Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain,0,0,0,0,0
COG4769,S,Predicted membrane protein,0,0,0,0,0
COG4770,I,"Acetyl/propionyl-CoA carboxylase, alpha subunit",1,8,144,20,173
COG4771,P,Outer membrane receptor for ferrienterochelin and colicins,1,2,0,3,6
COG4772,P,Outer membrane receptor for Fe3+-dicitrate,0,4,0,2,6
COG4773,P,Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid,1,3,0,1,5
COG4774,P,Outer membrane receptor for monomeric catechols,0,11,0,2,13
COG4775,M,Outer membrane protein/protective antigen OMA87,2,7,0,12,21
COG4776,K,Exoribonuclease II,0,0,0,0,0
COG4778,P,"ABC-type phosphonate transport system, ATPase component",0,0,0,0,0
COG4779,P,"ABC-type enterobactin transport system, permease component",0,1,37,6,44
COG4781,C,Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase,0,0,0,0,0
COG4782,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4783,R,"Putative Zn-dependent protease, contains TPR repeats",1,12,0,24,37
COG4784,R,Putative Zn-dependent protease,1,0,0,1,2
COG4785,R,"Lipoprotein NlpI, contains TPR repeats",0,1,0,3,4
COG4786,N,Flagellar basal body rod protein,0,1,0,0,1
COG4787,N,Flagellar basal body rod protein,0,2,0,0,2
COG4789,U,"Type III secretory pathway, component EscV",0,0,0,0,0
COG4790,U,"Type III secretory pathway, component EscR",0,0,0,0,0
COG4791,U,"Type III secretory pathway, component EscT",0,0,0,0,0
COG4792,U,"Type III secretory pathway, component EscU",0,0,0,0,0
COG4794,U,"Type III secretory pathway, component EscS",0,0,0,0,0
COG4795,U,"Type II secretory pathway, component PulJ",0,0,0,0,0
COG4796,U,"Type II secretory pathway, component HofQ",2,2,0,0,4
COG4797,R,Predicted regulatory domain of a methyltransferase,0,0,0,0,0
COG4798,R,Predicted methyltransferase,0,0,0,0,0
COG4799,I,"Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)",1,16,85,25,127
COG4800,K,Predicted transcriptional regulator with an HTH domain,0,0,0,0,0
COG4801,R,Predicted acyltransferase,0,0,0,0,0
COG4802,C,"Ferredoxin-thioredoxin reductase, catalytic subunit",0,0,0,8,8
COG4803,S,Predicted membrane protein,0,0,0,0,0
COG4804,S,Uncharacterized conserved protein,0,4,24,3,31
COG4805,S,Uncharacterized protein conserved in bacteria,1,0,22,28,51
COG4806,G,L-rhamnose isomerase,0,0,0,0,0
COG4807,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4808,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4809,G,Archaeal ADP-dependent phosphofructokinase/glucokinase,0,0,0,0,0
COG4810,E,Ethanolamine utilization protein,0,0,0,0,0
COG4811,S,Predicted membrane protein,0,0,0,0,0
COG4812,E,Ethanolamine utilization cobalamin adenosyltransferase,0,0,0,0,0
COG4813,G,Trehalose utilization protein,0,0,0,2,2
COG4814,R,Uncharacterized protein with an alpha/beta hydrolase fold,0,0,0,0,0
COG4815,S,Uncharacterized protein conserved in bacteria,0,1,13,1,15
COG4816,E,Ethanolamine utilization protein,0,0,0,0,0
COG4817,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4818,S,Predicted membrane protein,0,0,13,1,14
COG4819,E,"Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition",0,0,0,0,0
COG4820,E,"Ethanolamine utilization protein, possible chaperonin",0,0,0,0,0
COG4821,R,Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain,0,0,0,0,0
COG4822,H,"Cobalamin biosynthesis protein CbiK, Co2+ chelatase",0,0,0,0,0
COG4823,V,Abortive infection bacteriophage resistance protein,0,0,0,0,0
COG4824,R,Phage-related holin (Lysis protein),0,0,0,0,0
COG4825,S,Uncharacterized membrane-anchored protein conserved in bacteria,0,0,0,0,0
COG4826,O,Serine protease inhibitor,0,1,0,0,1
COG4827,R,Predicted transporter,0,0,0,0,0
COG4828,S,Predicted membrane protein,0,0,0,1,1
COG4829,Q,Muconolactone delta-isomerase,0,1,15,2,18
COG4830,J,Ribosomal protein S26,0,0,0,1,1
COG4831,S,Uncharacterized conserved protein,0,0,0,0,0
COG4832,S,Uncharacterized conserved protein,0,0,4,0,4
COG4833,G,Predicted glycosyl hydrolase,0,0,20,1,21
COG4834,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4835,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4836,S,Predicted membrane protein,0,0,0,0,0
COG4837,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4838,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4839,D,Protein required for the initiation of cell division,0,0,0,0,0
COG4840,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4841,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4842,S,Uncharacterized protein conserved in bacteria,0,0,15,0,15
COG4843,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4844,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4845,V,Chloramphenicol O-acetyltransferase,0,1,0,0,1
COG4846,O,Membrane protein involved in cytochrome C biogenesis,0,0,0,0,0
COG4847,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4848,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4849,S,Uncharacterized protein conserved in bacteria,0,1,0,0,1
COG4850,S,Uncharacterized conserved protein,0,0,16,1,17
COG4851,R,Protein involved in sex pheromone biosynthesis,0,0,0,0,0
COG4852,S,Predicted membrane protein,0,0,0,0,0
COG4853,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4854,S,Predicted membrane protein,0,0,0,0,0
COG4855,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4856,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4857,R,Predicted kinase,0,0,0,0,0
COG4858,S,Uncharacterized membrane-bound protein conserved in bacteria,0,0,0,0,0
COG4859,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4860,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4861,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4862,OTN,"Negative regulator of genetic competence, sporulation and motility",0,0,0,0,0
COG4863,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4864,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG4865,E,Glutamate mutase epsilon subunit,0,2,0,1,3
COG4866,S,Uncharacterized conserved protein,0,0,0,0,0
COG4867,R,Uncharacterized protein with a von Willebrand factor type A (vWA) domain,0,3,0,4,7
COG4868,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4869,Q,Propanediol utilization protein,0,0,0,0,0
COG4870,O,Cysteine protease,0,0,2,2,4
COG4871,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4872,S,Predicted membrane protein,0,0,0,0,0
COG4873,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4874,S,Uncharacterized protein conserved in bacteria containing a pentein-type domain,0,1,0,3,4
COG4875,S,Uncharacterized protein conserved in bacteria with a cystatin-like fold,0,0,0,1,1
COG4876,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4877,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4878,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4879,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4880,R,Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats,0,0,0,0,0
COG4881,S,Predicted membrane protein,0,0,0,0,0
COG4882,R,"Predicted aminopeptidase, Iap family",0,0,0,0,0
COG4883,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4884,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4885,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4886,S,Leucine-rich repeat (LRR) protein,0,0,0,0,0
COG4887,R,Uncharacterized metal-binding protein conserved in archaea,0,0,0,0,0
COG4888,R,Uncharacterized Zn ribbon-containing protein,0,0,0,0,0
COG4889,R,Predicted helicase,1,0,0,0,1
COG4890,S,Predicted outer membrane lipoprotein,0,0,0,0,0
COG4891,S,Uncharacterized conserved protein,0,0,0,1,1
COG4892,R,Predicted heme/steroid binding protein,0,0,0,0,0
COG4893,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4894,S,Uncharacterized conserved protein,0,0,13,0,13
COG4895,S,Uncharacterized conserved protein,0,0,0,1,1
COG4896,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4897,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4898,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4899,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4900,R,Predicted metallopeptidase,0,0,0,0,0
COG4901,J,Ribosomal protein S25,0,0,0,0,0
COG4902,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4903,K,Genetic competence transcription factor,0,0,0,0,0
COG4904,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4905,S,Predicted membrane protein,0,0,0,0,0
COG4906,S,Predicted membrane protein,0,0,0,0,0
COG4907,S,Predicted membrane protein,0,1,0,2,3
COG4908,R,Uncharacterized protein containing a NRPS condensation (elongation) domain,0,0,0,0,0
COG4909,Q,"Propanediol dehydratase, large subunit",0,0,0,0,0
COG4910,Q,"Propanediol dehydratase, small subunit",0,0,0,0,0
COG4911,S,Uncharacterized conserved protein,0,0,0,2,2
COG4912,L,Predicted DNA alkylation repair enzyme,0,0,3,1,4
COG4913,S,Uncharacterized protein conserved in bacteria,0,0,26,1,27
COG4914,R,Predicted nucleotidyltransferase,0,0,0,0,0
COG4915,R,5-bromo-4-chloroindolyl phosphate hydrolysis protein,0,0,0,0,0
COG4916,S,Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain,0,0,0,0,0
COG4917,E,Ethanolamine utilization protein,0,0,0,0,0
COG4918,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4919,J,Ribosomal protein S30,0,0,0,0,0
COG4920,S,Predicted membrane protein,0,0,0,0,0
COG4921,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG4922,S,Uncharacterized protein conserved in bacteria,1,1,2,3,7
COG4923,S,Uncharacterized conserved protein,0,0,0,3,3
COG4924,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4925,S,Uncharacterized conserved protein,0,0,0,0,0
COG4926,S,Phage-related protein,0,0,0,0,0
COG4927,R,Predicted choloylglycine hydrolase,0,0,0,0,0
COG4928,R,Predicted P-loop ATPase,0,0,12,1,13
COG4929,S,Uncharacterized membrane-anchored protein,0,0,0,0,0
COG4930,O,Predicted ATP-dependent Lon-type protease,0,0,0,0,0
COG4932,M,Predicted outer membrane protein,0,0,16,0,16
COG4933,S,Uncharacterized conserved protein,0,0,0,0,0
COG4934,O,Predicted protease,0,0,0,1,1
COG4935,O,Regulatory P domain of the subtilisin-like proprotein convertases and other proteases,0,0,0,0,0
COG4936,TK,Predicted sensor domain,0,0,0,0,0
COG4937,J,Predicted regulatory domain of prephenate dehydrogenase,0,0,0,0,0
COG4938,S,Uncharacterized conserved protein,0,0,0,0,0
COG4939,S,"Major membrane immunogen, membrane-anchored lipoprotein",0,0,0,0,0
COG4940,U,Competence protein ComGF,0,0,0,0,0
COG4941,K,Predicted RNA polymerase sigma factor containing a TPR repeat domain,0,6,0,15,21
COG4942,D,Membrane-bound metallopeptidase,0,3,1,9,13
COG4943,T,Predicted signal transduction protein containing sensor and EAL domains,0,2,0,1,3
COG4944,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4945,G,Membrane-anchored protein predicted to be involved in regulation of amylopullulanase,0,0,0,0,0
COG4946,S,Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system,1,3,0,3,7
COG4947,S,Uncharacterized protein conserved in bacteria,0,5,0,1,6
COG4948,MR,L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily,0,10,103,25,138
COG4949,S,Uncharacterized membrane-anchored protein conserved in bacteria,0,2,0,0,2
COG4950,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4951,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4952,M,Predicted sugar isomerase,0,0,0,1,1
COG4953,M,Membrane carboxypeptidase/penicillin-binding protein PbpC,1,0,0,4,5
COG4954,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4955,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4956,R,Integral membrane protein (PIN domain superfamily),1,1,2,4,8
COG4957,K,Predicted transcriptional regulator,1,0,0,1,2
COG4959,OU,"Type IV secretory pathway, protease TraF",0,0,0,1,1
COG4960,OU,"Flp pilus assembly protein, protease CpaA",0,0,0,0,0
COG4961,U,Flp pilus assembly protein TadG,0,3,0,0,3
COG4962,U,"Flp pilus assembly protein, ATPase CpaF",1,3,28,10,42
COG4963,U,"Flp pilus assembly protein, ATPase CpaE",0,6,0,3,9
COG4964,U,"Flp pilus assembly protein, secretin CpaC",0,3,0,8,11
COG4965,U,Flp pilus assembly protein TadB,0,3,40,2,45
COG4966,NU,Tfp pilus assembly protein PilW,0,1,0,0,1
COG4967,NU,Tfp pilus assembly protein PilV,0,3,0,1,4
COG4968,NU,Tfp pilus assembly protein PilE,2,0,0,4,6
COG4969,NU,"Tfp pilus assembly protein, major pilin PilA",0,1,0,0,1
COG4970,NU,Tfp pilus assembly protein FimT,1,2,0,1,4
COG4972,NU,"Tfp pilus assembly protein, ATPase PilM",3,5,0,6,14
COG4973,L,Site-specific recombinase XerC,0,1,0,0,1
COG4974,L,Site-specific recombinase XerD,2,23,62,34,121
COG4975,G,Putative glucose uptake permease,0,0,0,0,0
COG4976,R,Predicted methyltransferase (contains TPR repeat),0,0,0,0,0
COG4977,K,Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain,0,32,0,9,41
COG4978,KT,"Transcriptional regulator, effector-binding domain/component",0,0,0,0,0
COG4980,R,Gas vesicle protein,0,0,0,0,0
COG4981,I,Enoyl reductase domain of yeast-type FAS1,0,0,0,0,0
COG4982,I,3-oxoacyl-[acyl-carrier protein] reductase,0,0,0,0,0
COG4983,S,Uncharacterized conserved protein,0,1,0,0,1
COG4984,S,Predicted membrane protein,0,0,0,0,0
COG4985,P,"ABC-type phosphate transport system, auxiliary component",0,1,0,0,1
COG4986,P,"ABC-type anion transport system, duplicated permease component",0,0,0,0,0
COG4987,CO,"ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components",0,0,8,0,8
COG4988,CO,"ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components",0,1,31,1,33
COG4989,R,Predicted oxidoreductase,0,0,0,0,0
COG4990,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG4991,S,Uncharacterized protein with a bacterial SH3 domain homologue,0,0,0,0,0
COG4992,E,Ornithine/acetylornithine aminotransferase,0,8,14,6,28
COG4993,G,Glucose dehydrogenase,4,13,1,32,50
COG4994,S,Uncharacterized protein conserved in bacteria,0,0,2,0,2
COG4995,S,Uncharacterized protein conserved in bacteria,1,8,0,4,13
COG4996,R,Predicted phosphatase,0,0,0,0,0
COG4997,S,Uncharacterized conserved protein,0,0,0,0,0
COG4998,L,Predicted endonuclease (RecB family),0,0,0,0,0
COG4999,T,Uncharacterized domain of BarA-like signal transduction histidine kinases,0,0,0,0,0
COG5000,T,Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation,1,4,3,15,23
COG5001,T,"Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain",0,7,14,1,22
COG5002,T,Signal transduction histidine kinase,2,5,21,27,55
COG5003,R,Mu-like prophage protein gp37,0,0,0,0,0
COG5004,R,P2-like prophage tail protein X,0,0,0,0,0
COG5005,R,Mu-like prophage protein gpG,0,0,0,0,0
COG5006,R,"Predicted permease, DMT superfamily",0,3,45,6,54
COG5007,K,"Predicted transcriptional regulator, BolA superfamily",0,1,0,0,1
COG5008,NU,"Tfp pilus assembly protein, ATPase PilU",0,7,0,1,8
COG5009,M,Membrane carboxypeptidase/penicillin-binding protein,2,6,0,12,20
COG5010,U,"Flp pilus assembly protein TadD, contains TPR repeats",1,7,1,11,20
COG5011,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5012,R,Predicted cobalamin binding protein,0,0,0,3,3
COG5013,C,Nitrate reductase alpha subunit,0,6,0,0,6
COG5014,R,Predicted Fe-S oxidoreductase,0,0,0,0,0
COG5015,S,Uncharacterized conserved protein,0,0,0,0,0
COG5016,C,Pyruvate/oxaloacetate carboxyltransferase,1,4,16,2,23
COG5017,S,Uncharacterized conserved protein,0,0,0,0,0
COG5018,R,"Inhibitor of the KinA pathway to sporulation, predicted exonuclease",0,2,0,0,2
COG5019,DZ,Septin family protein,0,0,0,0,0
COG5020,G,Mannosyltransferase,0,0,0,0,0
COG5021,O,Ubiquitin-protein ligase,0,0,0,0,0
COG5022,Z,Myosin heavy chain,0,0,0,0,0
COG5023,Z,Tubulin,0,0,0,0,0
COG5024,D,Cyclin,0,0,0,0,0
COG5025,K,Transcription factor of the Forkhead/HNF3 family,0,0,0,0,0
COG5026,G,Hexokinase,0,0,0,0,0
COG5027,B,Histone acetyltransferase (MYST family),0,0,0,0,0
COG5028,U,"Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3",0,0,0,0,0
COG5029,O,"Prenyltransferase, beta subunit",0,0,0,0,0
COG5030,U,"Clathrin adaptor complex, small subunit",0,0,0,0,0
COG5031,H,Uncharacterized protein involved in ubiquinone biosynthesis,1,0,0,0,1
COG5032,TDBLU,Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family,0,0,0,0,0
COG5033,K,"Transcription initiation factor IIF, auxiliary subunit",0,0,0,0,0
COG5034,B,"Chromatin remodeling protein, contains PhD zinc finger",0,0,0,0,0
COG5035,DKT,Cell cycle control protein,0,0,0,0,0
COG5036,P,SPX domain-containing protein involved in vacuolar polyphosphate accumulation,0,0,0,0,0
COG5037,TG,Gluconate transport-inducing protein,0,0,0,0,0
COG5038,R,"Ca2+-dependent lipid-binding protein, contains C2 domain",0,0,0,0,0
COG5039,GM,Exopolysaccharide biosynthesis protein,0,0,0,0,0
COG5040,T,14-3-3 family protein,0,0,0,0,0
COG5041,TDK,"Casein kinase II, beta subunit",0,0,0,0,0
COG5042,F,Purine nucleoside permease,0,1,0,0,1
COG5043,U,Vacuolar protein sorting-associated protein,0,0,0,0,0
COG5044,O,RAB proteins geranylgeranyltransferase component A (RAB escort protein),0,0,0,0,0
COG5045,J,Ribosomal protein S10E,0,0,0,0,0
COG5046,O,Protein involved in Mod5 protein sorting,0,0,0,0,0
COG5047,U,"Vesicle coat complex COPII, subunit SEC23",0,0,0,0,0
COG5048,R,FOG: Zn-finger,0,0,0,0,0
COG5049,LDA,5'-3' exonuclease,0,0,0,0,0
COG5050,I,"sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases",0,0,0,0,0
COG5051,J,Ribosomal protein L36E,0,0,0,0,0
COG5052,U,Protein involved in membrane traffic,0,0,0,0,0
COG5053,J,Translation initiation factor 4E (eIF-4E),0,0,0,0,0
COG5054,O,Mitochondrial sulfhydryl oxidase involved in the biogenesis of cytosolic Fe/S proteins,0,0,0,0,0
COG5055,L,Recombination DNA repair protein (RAD52 pathway),0,1,0,0,1
COG5056,I,Acyl-CoA cholesterol acyltransferase,0,0,0,0,0
COG5057,DT,Phosphotyrosyl phosphatase activator,0,0,0,0,0
COG5058,U,"Protein transporter of the TRAM (translocating chain-associating membrane) superfamily, longevity assurance factor",0,0,0,0,0
COG5059,Z,Kinesin-like protein,0,0,0,0,0
COG5061,OU,"Oxidoreductin, endoplasmic reticulum membrane-associated protein involved in disulfide bond formation",0,0,0,0,0
COG5062,S,Uncharacterized membrane protein,0,0,0,0,0
COG5063,R,CCCH-type Zn-finger protein,0,0,0,0,0
COG5064,U,Karyopherin (importin) alpha,0,0,0,0,0
COG5065,P,Protein involved in inorganic phosphate transport,0,0,0,0,0
COG5066,U,VAMP-associated protein involved in inositol metabolism,0,0,0,0,0
COG5067,LD,Protein kinase essential for the initiation of DNA replication,0,0,0,0,0
COG5068,K,Regulator of arginine metabolism and related MADS box-containing transcription factors,0,0,0,0,0
COG5069,Z,Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily),0,0,0,0,0
COG5070,GOU,Nucleotide-sugar transporter,0,0,0,0,0
COG5071,O,26S proteasome regulatory complex component,0,0,0,0,0
COG5072,D,Serine/threonine kinase of the haspin family,0,0,0,0,0
COG5073,U,Vacuolar import and degradation protein,0,0,0,0,0
COG5074,U,"t-SNARE complex subunit, syntaxin",0,0,0,0,0
COG5075,S,Uncharacterized conserved protein,0,0,0,0,0
COG5076,BK,"Transcription factor involved in chromatin remodeling, contains bromodomain",0,0,0,0,0
COG5077,O,Ubiquitin carboxyl-terminal hydrolase,0,0,0,0,0
COG5078,O,Ubiquitin-protein ligase,0,0,0,0,0
COG5079,UD,Nuclear protein export factor,0,0,0,0,0
COG5080,U,"Rab GTPase interacting factor, Golgi membrane protein",0,0,0,0,0
COG5081,S,Predicted membrane protein,0,0,0,0,0
COG5082,OU,"Arginine methyltransferase-interacting protein, contains RING Zn-finger",0,0,0,0,0
COG5083,R,Uncharacterized protein involved in plasmid maintenance,0,0,0,0,0
COG5084,R,Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins,0,0,0,0,0
COG5085,S,Predicted membrane protein,0,0,0,0,0
COG5086,S,Uncharacterized conserved protein,0,0,0,0,0
COG5087,S,Uncharacterized conserved protein,0,0,0,0,0
COG5088,R,Rad5p-binding protein,0,0,0,0,0
COG5090,K,"Transcription initiation factor IIF, small subunit (RAP30)",0,0,0,0,0
COG5091,R,Suppressor of G2 allele of skp1 and related proteins,0,0,0,0,0
COG5092,I,N-myristoyl transferase,0,0,0,0,0
COG5093,S,Uncharacterized conserved protein,0,0,0,0,0
COG5094,K,"Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)",0,0,0,0,0
COG5095,K,"Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA)",0,0,0,0,0
COG5096,U,"Vesicle coat complex, various subunits",0,0,0,0,0
COG5097,K,RNA polymerase II transcriptional regulation mediator,0,0,0,0,0
COG5098,BD,"Chromosome condensation complex Condensin, subunit D2",0,0,0,0,0
COG5099,J,"RNA-binding protein of the Puf family, translational repressor",0,0,0,0,0
COG5100,Y,Nuclear pore protein,0,0,0,0,0
COG5101,YU,Importin beta-related nuclear transport receptor,0,0,0,0,0
COG5102,U,Membrane protein involved in ER to Golgi transport,0,0,0,0,0
COG5103,DK,"Cell division control protein, negative regulator of transcription",0,0,0,0,0
COG5104,A,Splicing factor,0,0,0,0,0
COG5105,D,"Mitotic inducer, protein phosphatase",0,0,0,0,0
COG5106,S,Uncharacterized conserved protein,0,0,0,0,0
COG5107,A,Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor,0,0,0,0,0
COG5108,K,Mitochondrial DNA-directed RNA polymerase,0,3,0,0,3
COG5109,R,"Uncharacterized conserved protein, contains RING Zn-finger",0,0,0,0,0
COG5110,O,26S proteasome regulatory complex component,0,0,0,0,0
COG5111,K,"DNA-directed RNA polymerase III, subunit C34",0,0,0,0,0
COG5112,R,U1-like Zn-finger-containing protein,0,0,0,0,0
COG5113,O,Ubiquitin fusion degradation protein 2,0,0,0,0,0
COG5114,B,"Histone acetyltransferase complex SAGA/ADA, subunit ADA2",0,0,0,0,0
COG5116,O,26S proteasome regulatory complex component,0,0,0,0,0
COG5117,JU,Protein involved in the nuclear export of pre-ribosomes,0,0,0,0,0
COG5118,K,"Transcription initiation factor TFIIIB, Bdp1 subunit",0,0,0,0,0
COG5119,R,"Uncharacterized protein, contains ParB-like nuclease domain",0,0,0,0,0
COG5120,U,Membrane protein involved in Golgi transport,0,0,0,0,0
COG5122,U,Transport protein particle (TRAPP) complex subunit,0,0,0,0,0
COG5123,K,"Transcription initiation factor IIA, gamma subunit",0,0,0,0,0
COG5124,DR,Protein predicted to be involved in meiotic recombination,0,0,0,0,0
COG5125,S,Uncharacterized conserved protein,0,0,0,0,0
COG5126,TZDR,Ca2+-binding protein (EF-Hand superfamily),0,0,0,0,0
COG5127,C,"Vacuolar H+-ATPase V1 sector, subunit C",0,0,0,0,0
COG5128,U,Transport protein particle (TRAPP) complex subunit,0,0,0,0,0
COG5129,R,Nuclear protein with HMG-like acidic region,0,0,0,0,0
COG5130,UT,Prenylated rab acceptor 1 and related proteins,0,0,0,0,0
COG5131,O,Ubiquitin-like protein,0,0,0,0,0
COG5132,KD,"Cell cycle control protein, G10 family",0,0,0,0,0
COG5133,S,Uncharacterized conserved protein,0,0,0,0,0
COG5134,S,Uncharacterized conserved protein,0,0,0,0,0
COG5135,S,Uncharacterized conserved protein,0,0,0,0,0
COG5136,A,U1 snRNP-specific protein C,0,0,0,0,0
COG5137,KB,Histone chaperone involved in gene silencing,0,0,0,0,0
COG5138,S,Uncharacterized conserved protein,0,0,0,0,0
COG5139,S,Uncharacterized conserved protein,0,0,0,0,0
COG5140,O,Ubiquitin fusion-degradation protein,0,0,0,0,0
COG5141,R,PHD zinc finger-containing protein,0,0,0,0,0
COG5142,L,Oxidation resistance protein,0,0,0,0,0
COG5143,U,Synaptobrevin/VAMP-like protein,0,0,0,0,0
COG5144,KL,"RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB2",0,0,0,0,0
COG5145,L,DNA excision repair protein,0,0,0,0,0
COG5146,H,"Pantothenate kinase, acetyl-CoA regulated",0,0,0,0,0
COG5147,KAD,"Myb superfamily proteins, including transcription factors and mRNA splicing factors",0,0,0,0,0
COG5148,O,"26S proteasome regulatory complex, subunit RPN10/PSMD4",0,0,0,0,0
COG5149,K,"Transcription initiation factor IIA, large chain",0,0,0,0,0
COG5150,K,"Class 2 transcription repressor NC2, beta subunit (Dr1)",0,0,0,0,0
COG5151,KL,"RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1",0,0,0,0,0
COG5152,R,"Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers",0,0,0,0,0
COG5153,UI,Putative lipase essential for disintegration of autophagic bodies inside the vacuole,0,0,0,0,0
COG5154,J,RNA-binding protein required for 60S ribosomal subunit biogenesis,0,0,0,0,0
COG5155,DO,"Separase, a protease involved in sister chromatid separation",0,0,0,0,0
COG5156,DO,"Anaphase-promoting complex (APC), subunit 10",0,0,0,0,0
COG5157,K,RNA polymerase II assessory factor,0,0,0,0,0
COG5158,U,"Proteins involved in synaptic transmission and general secretion, Sec1 family",0,0,0,0,0
COG5159,O,26S proteasome regulatory complex component,0,0,0,0,0
COG5160,O,"Protease, Ulp1 family",0,0,0,0,0
COG5161,A,Pre-mRNA cleavage and polyadenylation specificity factor,0,0,0,0,0
COG5162,K,"Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA)",0,0,0,0,0
COG5163,J,Protein required for biogenesis of the 60S ribosomal subunit,0,0,0,0,0
COG5164,K,Transcription elongation factor,0,0,0,0,0
COG5165,KLB,"Nucleosome-binding factor SPN, POB3 subunit",0,0,0,0,0
COG5166,S,Uncharacterized conserved protein,0,0,0,0,0
COG5167,U,Protein involved in vacuole import and degradation,0,0,0,0,0
COG5169,K,Heat shock transcription factor,0,0,0,0,0
COG5170,T,"Serine/threonine protein phosphatase 2A, regulatory subunit",0,0,0,0,0
COG5171,U,Ran GTPase-activating protein (Ran-binding protein),0,0,0,0,0
COG5173,U,Exocyst complex subunit SEC6,0,0,0,0,0
COG5174,K,"Transcription initiation factor IIE, beta subunit",0,0,0,0,0
COG5175,K,Transcriptional repressor,0,0,0,0,0
COG5176,A,Splicing factor (branch point binding protein),0,0,0,0,0
COG5177,S,Uncharacterized conserved protein,0,0,0,0,0
COG5178,A,U5 snRNP spliceosome subunit,0,0,0,4,4
COG5179,K,"Transcription initiation factor TFIID, subunit TAF1",0,0,0,0,0
COG5180,A,Protein interacting with poly(A)-binding protein,0,0,0,0,0
COG5181,A,U2 snRNP spliceosome subunit,0,0,0,0,0
COG5182,A,"Splicing factor 3b, subunit 2",0,0,0,0,0
COG5183,A,Protein involved in mRNA turnover and stability,0,0,0,0,0
COG5184,DZ,Alpha-tubulin suppressor and related RCC1 domain-containing proteins,1,0,0,1,2
COG5185,D,"Protein involved in chromosome segregation, interacts with SMC proteins",0,0,0,0,0
COG5186,A,Poly(A) polymerase,0,0,0,0,0
COG5187,O,"26S proteasome regulatory complex component, contains PCI domain",0,0,0,0,0
COG5188,A,"Splicing factor 3a, subunit 3",0,0,0,0,0
COG5189,KD,Putative transcriptional repressor regulating G2/M transition,0,0,0,0,0
COG5190,K,"TFIIF-interacting CTD phosphatases, including NLI-interacting factor",0,0,0,0,0
COG5191,R,"Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat",0,0,0,0,0
COG5192,J,GTP-binding protein required for 40S ribosome biogenesis,0,0,0,0,0
COG5193,OJ,"La protein, small RNA-binding pol III transcript stabilizing protein and related La-motif-containing proteins involved in translation",0,0,0,0,0
COG5194,OD,Component of SCF ubiquitin ligase and anaphase-promoting complex,0,0,0,0,0
COG5195,S,Uncharacterized conserved protein,0,0,0,0,0
COG5196,U,ER lumen protein retaining receptor,0,0,0,0,0
COG5197,S,Predicted membrane protein,0,0,0,0,0
COG5198,R,Protein tyrosine phosphatase-like protein (contains Pro instead of catalytic Arg),0,0,0,0,0
COG5199,Z,Calponin,0,0,0,0,0
COG5200,A,"U1 snRNP component, mediates U1 snRNP association with cap-binding complex",0,0,0,0,0
COG5201,O,"SCF ubiquitin ligase, SKP1 component",0,0,0,0,0
COG5202,S,Predicted membrane protein,0,0,0,0,0
COG5204,K,Transcription elongation factor SPT4,0,0,0,0,0
COG5206,O,"Glycosylphosphatidylinositol transamidase (GPIT), subunit GPI8",0,0,0,0,0
COG5207,O,Isopeptidase T,0,0,0,0,0
COG5208,K,"CCAAT-binding factor, subunit C",0,0,0,0,0
COG5209,R,Uncharacterized protein involved in cell differentiation/sexual development,0,0,0,0,0
COG5210,R,GTPase-activating protein,0,0,0,0,0
COG5211,K,RNA polymerase II-interacting protein involved in transcription start site selection,0,0,0,0,0
COG5212,T,Low-affinity cAMP phosphodiesterase,0,0,0,0,0
COG5213,A,"Polyadenylation factor I complex, subunit FIP1",0,0,0,0,0
COG5214,L,"DNA polymerase alpha-primase complex, polymerase-associated subunit B",0,0,0,0,0
COG5215,U,Karyopherin (importin) beta,0,0,0,0,0
COG5216,S,Uncharacterized conserved protein,0,0,0,0,0
COG5217,DZ,Microtubule-binding protein involved in cell cycle control,0,0,0,0,0
COG5218,BD,"Chromosome condensation complex Condensin, subunit G",0,0,0,0,0
COG5219,R,"Uncharacterized conserved protein, contains RING Zn-finger",0,0,0,0,0
COG5220,DKL,"Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3",0,0,0,0,0
COG5221,K,Dopey and related predicted leucine zipper transcription factors,0,0,0,0,0
COG5222,R,"Uncharacterized conserved protein, contains RING Zn-finger",0,0,0,0,0
COG5223,S,Uncharacterized conserved protein,0,0,0,0,0
COG5224,K,"CCAAT-binding factor, subunit B",0,0,0,0,0
COG5225,J,Uncharacterized protein involved in ribosome biogenesis,0,0,0,0,0
COG5226,A,"mRNA capping enzyme, guanylyltransferase (alpha) subunit",0,0,0,0,0
COG5227,O,Ubiquitin-like protein (sentrin),0,0,0,0,0
COG5228,A,mRNA deadenylase subunit,0,0,0,0,0
COG5229,BD,"Chromosome condensation complex Condensin, subunit H",0,0,0,0,0
COG5230,S,Uncharacterized conserved protein,0,0,0,0,0
COG5231,C,"Vacuolar H+-ATPase V1 sector, subunit H",0,0,0,0,0
COG5232,U,Preprotein translocase subunit Sec62,0,0,0,0,0
COG5233,U,Peripheral Golgi membrane protein,0,0,0,0,0
COG5234,OZ,Beta-tubulin folding cofactor D,0,0,0,0,0
COG5235,L,"Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit",0,0,0,0,0
COG5236,R,"Uncharacterized conserved protein, contains RING Zn-finger",0,0,0,0,0
COG5237,S,Predicted membrane protein,0,0,0,0,0
COG5238,TA,Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport,0,0,0,0,0
COG5239,A,"mRNA deadenylase, exonuclease subunit and related nucleases",0,0,0,0,0
COG5240,U,"Vesicle coat complex COPI, gamma subunit",0,0,0,0,0
COG5241,L,"Nucleotide excision repair endonuclease NEF1, RAD10 subunit",0,0,0,0,0
COG5242,KL,"RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB4",0,0,0,0,0
COG5243,O,"HRD ubiquitin ligase complex, ER membrane component",0,0,0,0,0
COG5244,D,Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B,0,0,0,0,0
COG5245,Z,"Dynein, heavy chain",0,0,0,0,0
COG5246,A,"Splicing factor 3a, subunit 2",0,0,0,0,0
COG5247,K,"Class 2 transcription repressor NC2, alpha subunit (DRAP1 homolog)",0,0,0,0,0
COG5248,K,"Transcription initiation factor TFIID, subunit TAF13",0,0,0,0,0
COG5249,U,Golgi protein involved in Golgi-to-ER retrieval,0,0,0,0,0
COG5250,K,"RNA polymerase II, fourth largest subunit",0,0,0,0,0
COG5251,K,"Transcription initiation factor TFIID, subunit TAF11",0,0,0,0,0
COG5252,R,"Uncharacterized conserved protein, contains CCCH-type Zn-finger protein",0,0,0,0,0
COG5253,T,Phosphatidylinositol-4-phosphate 5-kinase,0,0,0,0,0
COG5254,S,Predicted membrane protein,0,0,0,0,0
COG5255,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5256,J,Translation elongation factor EF-1alpha (GTPase),0,0,1,5,6
COG5257,J,"Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)",0,0,2,3,5
COG5258,R,GTPase,0,0,0,0,0
COG5259,BK,RSC chromatin remodeling complex subunit RSC8,0,0,0,0,0
COG5260,L,DNA polymerase sigma,0,0,0,0,0
COG5261,DT,Protein involved in regulation of cellular morphogenesis/cytokinesis,0,0,0,0,0
COG5262,B,Histone H2A,0,0,0,0,0
COG5263,R,FOG: Glucan-binding domain (YG repeat),0,0,0,0,0
COG5264,O,Vacuolar transporter chaperone,0,0,0,0,0
COG5265,O,"ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components",2,0,4,2,8
COG5266,P,"ABC-type Co2+ transport system, periplasmic component",0,0,0,0,0
COG5267,S,Uncharacterized protein conserved in bacteria,0,0,1,1,2
COG5268,NU,"Type IV secretory pathway, TrbD component",0,0,0,0,0
COG5269,JO,Ribosome-associated chaperone zuotin,0,0,0,0,0
COG5270,J,PUA domain (predicted RNA-binding domain),0,0,0,0,0
COG5271,R,AAA ATPase containing von Willebrand factor type A (vWA) domain,0,0,0,0,0
COG5272,O,Ubiquitin,0,0,0,0,0
COG5273,R,Uncharacterized protein containing DHHC-type Zn finger,0,0,0,0,0
COG5274,CI,Cytochrome b involved in lipid metabolism,0,0,0,0,0
COG5275,R,BRCT domain type II,0,0,0,0,0
COG5276,S,Uncharacterized conserved protein,1,0,0,2,3
COG5277,Z,Actin and related proteins,0,0,0,0,0
COG5278,T,Predicted periplasmic ligand-binding sensor domain,0,0,0,0,0
COG5279,D,"Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain",0,0,0,0,0
COG5280,S,Phage-related minor tail protein,0,0,0,0,0
COG5281,S,Phage-related minor tail protein,0,0,0,0,0
COG5282,S,Uncharacterized conserved protein,0,0,35,0,35
COG5283,S,Phage-related tail protein,0,0,0,0,0
COG5285,Q,Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin,0,2,0,0,2
COG5290,K,"IkappaB kinase complex, IKAP component",0,0,0,0,0
COG5291,S,Predicted membrane protein,0,0,0,0,0
COG5293,S,Uncharacterized protein conserved in bacteria,0,0,13,0,13
COG5294,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5295,UW,Autotransporter adhesin,0,0,0,0,0
COG5296,K,Transcription factor involved in TATA site selection and in elongation by RNA polymerase II,0,0,0,0,0
COG5297,G,"Cellobiohydrolase A (1,4-beta-cellobiosidase A)",0,0,0,0,0
COG5298,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5301,R,Phage-related tail fibre protein,0,0,0,0,0
COG5302,R,Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid,0,0,0,0,0
COG5304,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5305,S,Predicted membrane protein,0,2,0,0,2
COG5306,S,Uncharacterized conserved protein,0,0,0,0,0
COG5307,R,SEC7 domain proteins,0,0,0,0,0
COG5308,U,Nuclear pore complex subunit,0,0,0,0,0
COG5309,G,"Exo-beta-1,3-glucanase",0,2,0,0,2
COG5310,Q,Homospermidine synthase,0,0,0,0,0
COG5314,U,Conjugal transfer/entry exclusion protein,0,0,0,0,0
COG5316,S,Uncharacterized conserved protein,0,0,0,1,1
COG5317,S,Uncharacterized protein conserved in bacteria,1,0,0,1,2
COG5319,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5321,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5322,R,Predicted dehydrogenase,0,0,0,0,0
COG5323,S,Uncharacterized conserved protein,2,11,0,5,18
COG5324,S,Uncharacterized conserved protein,0,0,0,0,0
COG5325,U,"t-SNARE complex subunit, syntaxin",0,0,0,0,0
COG5328,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5329,T,Phosphoinositide polyphosphatase (Sac family),0,0,0,0,0
COG5330,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5331,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG5333,DKL,"Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit",0,0,0,0,0
COG5336,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG5337,M,Spore coat assembly protein,0,1,0,2,3
COG5338,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5339,S,Uncharacterized protein conserved in bacteria,0,3,0,0,3
COG5340,K,Predicted transcriptional regulator,0,1,0,0,1
COG5341,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5342,R,"Invasion protein B, involved in pathogenesis",0,0,0,0,0
COG5343,S,Uncharacterized protein conserved in bacteria,1,0,1,0,2
COG5345,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG5346,S,Predicted membrane protein,0,0,0,0,0
COG5347,U,"GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport",0,0,0,0,0
COG5349,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5350,R,Predicted protein tyrosine phosphatase,0,0,0,0,0
COG5351,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5352,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5353,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5354,R,"Uncharacterized protein, contains Trp-Asp (WD) repeat",0,0,0,0,0
COG5360,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5361,S,Uncharacterized conserved protein,0,2,1,13,16
COG5362,R,Phage-related terminase,0,3,1,0,4
COG5366,R,Protein involved in propagation of M2 dsRNA satellite of L-A virus,0,0,0,0,0
COG5368,S,Uncharacterized protein conserved in bacteria,0,5,0,4,9
COG5369,S,Uncharacterized conserved protein,0,0,0,0,0
COG5371,GO,Golgi nucleoside diphosphatase,0,0,0,0,0
COG5373,S,Predicted membrane protein,0,4,1,11,16
COG5374,S,Uncharacterized conserved protein,0,0,0,0,0
COG5375,S,Uncharacterized protein conserved in bacteria,0,0,0,1,1
COG5377,L,"Phage-related protein, predicted endonuclease",0,3,0,0,3
COG5378,R,Predicted nucleotide-binding protein,0,0,0,0,0
COG5379,I,S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase,0,0,0,0,0
COG5380,O,Lipase chaperone,0,0,0,0,0
COG5381,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5383,S,Uncharacterized protein conserved in bacteria,0,2,0,0,2
COG5384,J,U3 small nucleolar ribonucleoprotein component,0,0,0,0,0
COG5385,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5386,M,Cell surface protein,0,0,0,0,0
COG5387,O,Chaperone required for the assembly of the mitochondrial F1-ATPase,0,0,0,0,0
COG5388,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5389,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5391,UR,Phox homology (PX) domain protein,0,0,0,0,0
COG5393,S,Predicted membrane protein,0,0,0,0,0
COG5394,S,Uncharacterized protein conserved in bacteria,0,1,0,1,2
COG5395,S,Predicted membrane protein,0,0,0,0,0
COG5397,S,Uncharacterized conserved protein,0,0,0,0,0
COG5398,P,Heme oxygenase,0,0,0,0,0
COG5399,S,Uncharacterized protein conserved in archaea,0,0,0,0,0
COG5400,S,Uncharacterized protein conserved in bacteria,0,0,0,0,0
COG5401,R,Spore germination protein,0,0,0,0,0
COG5402,S,Uncharacterized conserved protein,0,0,0,0,0
COG5403,S,Uncharacterized conserved protein,0,0,0,0,0
COG5404,D,"SOS-response cell division inhibitor, blocks FtsZ ring formation",0,1,0,0,1
COG5405,O,"ATP-dependent protease HslVU (ClpYQ), peptidase subunit",1,2,0,0,3
COG5406,KLB,"Nucleosome binding factor SPN, SPT16 subunit",0,0,0,0,0
COG5407,U,Preprotein translocase subunit Sec63,0,0,0,0,0
COG5408,T,SPX domain-containing protein,0,0,0,0,0
COG5409,T,EXS domain-containing protein,0,0,0,0,0
COG5410,S,Uncharacterized protein conserved in bacteria,0,1,0,11,12
COG5411,T,Phosphatidylinositol 5-phosphate phosphatase,0,0,0,0,0
COG5412,S,Phage-related protein,0,4,0,0,4
COG5413,S,Uncharacterized integral membrane protein,0,0,0,0,0
COG5414,K,TATA-binding protein-associated factor,0,0,0,0,0
COG5415,R,Predicted integral membrane metal-binding protein,0,0,0,0,0
COG5416,S,Uncharacterized integral membrane protein,0,0,13,0,13
COG5417,S,Uncharacterized small protein,0,0,0,0,0
COG5418,S,Predicted secreted protein,0,0,0,0,0
COG5419,S,Uncharacterized conserved protein,0,0,0,0,0
COG5420,S,Uncharacterized conserved small protein containing a coiled-coil domain,0,0,0,0,0
COG5421,L,Transposase,3,3,47,40,93
COG5422,T,"RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases",0,0,0,0,0
COG5423,S,Predicted metal-binding protein,0,0,0,0,0
COG5424,H,Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C,0,2,1,5,8
COG5425,E,"Usg protein, probable subunit of phosphoribosylanthranilate isomerase",0,0,0,0,0
COG5426,S,Uncharacterized membrane protein,0,0,0,2,2
COG5427,S,Uncharacterized membrane protein,0,0,0,0,0
COG5428,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5429,S,Uncharacterized secreted protein,0,0,0,0,0
COG5430,S,Uncharacterized secreted protein,0,0,0,0,0
COG5431,S,Uncharacterized metal-binding protein,0,0,0,0,0
COG5432,T,RING-finger-containing E3 ubiquitin ligase,0,0,0,0,0
COG5433,L,Transposase,1,1,0,4,6
COG5434,M,Endopolygalacturonase,2,2,0,4,8
COG5435,S,Uncharacterized conserved protein,0,0,0,0,0
COG5436,S,Predicted integral membrane protein,0,0,0,0,0
COG5437,S,Predicted secreted protein,0,0,0,0,0
COG5438,S,Predicted multitransmembrane protein,0,0,16,0,16
COG5439,S,Uncharacterized conserved protein,0,0,0,0,0
COG5440,S,Uncharacterized conserved protein,0,0,0,0,0
COG5441,S,Uncharacterized conserved protein,0,0,0,1,1
COG5442,N,Flagellar biosynthesis regulator FlaF,0,0,0,0,0
COG5443,N,Flagellar biosynthesis regulator FlbT,0,0,0,0,0
COG5444,S,Uncharacterized conserved protein,0,0,0,0,0
COG5445,S,Predicted secreted protein,0,0,0,0,0
COG5446,S,Predicted integral membrane protein,0,1,0,0,1
COG5447,S,Uncharacterized conserved protein,0,0,0,0,0
COG5448,S,Uncharacterized conserved protein,2,2,0,0,4
COG5449,S,Uncharacterized conserved protein,1,2,0,0,3
COG5450,K,Transcription regulator of the Arc/MetJ class,0,0,1,1,2
COG5451,S,Predicted secreted protein,0,0,0,0,0
COG5452,S,Uncharacterized conserved protein,0,0,0,0,0
COG5453,S,Uncharacterized conserved protein,0,0,0,0,0
COG5454,S,Predicted secreted protein,0,0,0,0,0
COG5455,S,Predicted integral membrane protein,0,0,0,0,0
COG5456,P,Predicted integral membrane protein linked to a cation pump,0,0,0,0,0
COG5457,S,Uncharacterized conserved small protein,0,2,0,0,2
COG5458,S,Uncharacterized conserved protein,0,0,0,0,0
COG5459,J,Predicted rRNA methylase,0,0,0,0,0
COG5460,S,Uncharacterized conserved protein,0,0,0,0,0
COG5461,N,Type IV pili component,0,0,0,0,0
COG5462,S,Predicted secreted (periplasmic) protein,0,0,0,0,0
COG5463,S,Predicted integral membrane protein,0,0,0,0,0
COG5464,S,Uncharacterized conserved protein,0,0,0,0,0
COG5465,S,Uncharacterized conserved protein,0,0,0,0,0
COG5466,S,Predicted small metal-binding protein,0,0,0,0,0
COG5467,S,Uncharacterized conserved protein,0,0,0,0,0
COG5468,S,Predicted secreted (periplasmic) protein,0,0,0,0,0
COG5469,S,Predicted metal-binding protein,0,0,0,0,0
COG5470,S,Uncharacterized conserved protein,0,0,0,8,8
COG5471,S,Uncharacterized conserved protein,0,0,0,0,0
COG5472,S,Predicted small integral membrane protein,0,0,0,0,0
COG5473,S,Predicted integral membrane protein,0,0,0,0,0
COG5474,S,Uncharacterized conserved protein,0,0,0,0,0
COG5475,S,Uncharacterized small protein,0,0,0,0,0
COG5476,S,Uncharacterized conserved protein,0,0,0,1,1
COG5477,S,Predicted small integral membrane protein,0,1,0,0,1
COG5478,S,Predicted small integral membrane protein,0,1,0,4,5
COG5479,M,Uncharacterized protein potentially involved in peptidoglycan biosynthesis,0,0,0,0,0
COG5480,S,Predicted integral membrane protein,0,0,0,0,0
COG5481,S,Uncharacterized conserved small protein containing a coiled-coil domain,0,0,0,0,0
COG5482,S,Uncharacterized conserved protein,0,0,0,0,0
COG5483,S,Uncharacterized conserved protein,4,1,14,2,21
COG5484,S,Uncharacterized conserved protein,0,0,0,0,0
COG5485,R,Predicted ester cyclase,2,0,0,9,11
COG5486,S,Predicted metal-binding integral membrane protein,0,0,1,2,3
COG5487,S,Small integral membrane protein,0,0,0,0,0
COG5488,S,Integral membrane protein,0,0,0,0,0
COG5489,S,Uncharacterized conserved protein,0,0,0,0,0
COG5490,S,Uncharacterized conserved protein,0,0,0,1,1
COG5491,N,Conserved protein implicated in secretion,0,0,0,4,4
COG5492,N,Bacterial surface proteins containing Ig-like domains,0,0,0,0,0
COG5493,S,Uncharacterized conserved protein containing a coiled-coil domain,0,0,0,0,0
COG5494,O,Predicted thioredoxin/glutaredoxin,0,0,0,0,0
COG5495,S,Uncharacterized conserved protein,0,1,17,0,18
COG5496,R,Predicted thioesterase,0,0,1,2,3
COG5497,S,Predicted secreted protein,0,0,0,0,0
COG5498,M,Predicted glycosyl hydrolase,0,0,0,0,0
COG5499,K,Predicted transcription regulator containing HTH domain,0,2,0,0,2
COG5500,S,Predicted integral membrane protein,0,0,0,1,1
COG5501,S,Predicted secreted protein,0,0,0,1,1
COG5502,S,Uncharacterized conserved protein,0,0,0,0,0
COG5503,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5504,O,Predicted Zn-dependent protease,0,0,0,0,0
COG5505,S,Predicted integral membrane protein,0,0,0,0,0
COG5506,S,Uncharacterized conserved protein,0,0,0,0,0
COG5507,S,Uncharacterized conserved protein,0,1,0,1,2
COG5508,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5509,S,Uncharacterized small protein containing a coiled-coil domain,0,0,0,0,0
COG5510,S,Predicted small secreted protein,0,0,0,0,0
COG5511,R,Bacteriophage capsid protein,0,0,0,0,0
COG5512,R,"Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives",0,0,14,0,14
COG5513,S,Predicted secreted protein,0,1,0,0,1
COG5514,S,Uncharacterized conserved protein,0,0,0,0,0
COG5515,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5516,R,"Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding",0,0,25,1,26
COG5517,Q,Small subunit of phenylpropionate dioxygenase,0,2,17,1,20
COG5518,R,Bacteriophage capsid portal protein,0,0,0,0,0
COG5519,L,Superfamily II helicase and inactivated derivatives,0,0,0,0,0
COG5520,M,O-Glycosyl hydrolase,0,1,0,3,4
COG5521,S,Predicted integral membrane protein,0,0,0,0,0
COG5522,S,Predicted integral membrane protein,0,0,0,0,0
COG5523,S,Predicted integral membrane protein,0,0,0,0,0
COG5524,R,Bacteriorhodopsin,0,0,0,0,0
COG5525,R,Bacteriophage tail assembly protein,0,0,0,0,0
COG5526,S,Uncharacterized conserved protein,0,0,0,1,1
COG5527,L,Protein involved in initiation of plasmid replication,0,0,0,0,0
COG5528,S,Predicted integral membrane protein,0,0,0,0,0
COG5529,R,Pyocin large subunit,0,0,0,0,0
COG5530,S,Predicted integral membrane protein,1,1,0,2,4
COG5531,B,SWIB-domain-containing proteins implicated in chromatin remodeling,0,0,0,2,2
COG5532,S,Uncharacterized conserved protein,0,1,0,0,1
COG5533,O,Ubiquitin C-terminal hydrolase,0,0,0,0,0
COG5534,L,Plasmid replication initiator protein,0,0,0,0,0
COG5535,L,DNA repair protein RAD4,0,0,0,0,0
COG5536,O,"Protein prenyltransferase, alpha subunit",0,0,0,0,0
COG5537,D,Cohesin,0,0,0,0,0
COG5538,U,Preprotein translocase subunit Sec66,0,0,0,0,0
COG5539,O,Predicted cysteine protease (OTU family),0,0,0,0,0
COG5540,O,RING-finger-containing ubiquitin ligase,0,0,0,0,0
COG5541,O,"Vesicle coat complex COPI, zeta subunit",0,0,0,0,0
COG5542,S,Predicted integral membrane protein,0,0,0,0,0
COG5543,S,Uncharacterized conserved protein,0,0,0,0,0
COG5544,R,Predicted periplasmic lipoprotein,0,0,0,0,0
COG5545,R,Predicted P-loop ATPase and inactivated derivatives,0,3,0,0,3
COG5546,S,Small integral membrane protein,0,0,0,0,0
COG5547,S,Small integral membrane protein,0,0,0,0,0
COG5548,S,Small integral membrane protein,0,0,0,1,1
COG5549,O,Predicted Zn-dependent protease,0,0,0,0,0
COG5550,O,Predicted aspartyl protease,0,1,0,0,1
COG5551,S,Uncharacterized conserved protein,0,0,0,0,0
COG5552,S,Uncharacterized conserved protein,0,0,0,1,1
COG5553,R,Predicted metal-dependent enzyme of the double-stranded beta helix superfamily,0,0,0,0,0
COG5554,Q,Nitrogen fixation protein,0,0,0,0,0
COG5555,N,"Cytolysin, a secreted calcineurin-like phosphatase",0,0,0,0,0
COG5556,S,Uncharacterized conserved protein,0,0,0,0,0
COG5557,C,Polysulphide reductase,0,1,0,1,2
COG5558,L,Transposase,0,0,0,0,0
COG5559,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5560,O,Ubiquitin C-terminal hydrolase,0,0,0,0,0
COG5561,S,Predicted metal-binding protein,0,0,0,0,0
COG5562,R,Phage envelope protein,0,0,0,0,0
COG5563,S,Predicted integral membrane proteins containing uncharacterized repeats,0,1,0,1,2
COG5564,R,"Predicted TIM-barrel enzyme, possibly a dioxygenase",0,0,0,0,0
COG5565,R,Bacteriophage terminase large (ATPase) subunit and inactivated derivatives,0,2,0,0,2
COG5566,S,Uncharacterized conserved protein,0,0,0,0,0
COG5567,N,Predicted small periplasmic lipoprotein,0,0,0,0,0
COG5568,S,Uncharacterized small protein,0,0,0,0,0
COG5569,S,Uncharacterized conserved protein,0,0,0,1,1
COG5570,S,Uncharacterized small protein,0,0,0,0,0
COG5571,N,"Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion",0,1,0,0,1
COG5572,S,Predicted integral membrane protein,0,0,0,0,0
COG5573,R,"Predicted nucleic-acid-binding protein, contains PIN domain",0,0,0,0,0
COG5574,O,RING-finger-containing E3 ubiquitin ligase,0,0,0,0,0
COG5575,L,"Origin recognition complex, subunit 2",0,0,0,0,0
COG5576,K,Homeodomain-containing transcription factor,0,0,0,0,0
COG5577,M,Spore coat protein,0,0,0,0,0
COG5578,S,Predicted integral membrane protein,0,0,0,0,0
COG5579,S,Uncharacterized conserved protein,0,4,0,0,4
COG5580,O,Activator of HSP90 ATPase,0,0,0,0,0
COG5581,M,Predicted glycosyltransferase,0,2,0,0,2
COG5582,S,Uncharacterized conserved protein,0,0,0,0,0
COG5583,S,Uncharacterized small protein,0,0,0,0,0
COG5584,S,Predicted small secreted protein,0,0,0,0,0
COG5585,T,NAD+--asparagine ADP-ribosyltransferase,0,0,0,0,0
COG5586,S,Uncharacterized conserved protein,0,0,0,0,0
COG5587,S,Uncharacterized conserved protein,0,0,0,0,0
COG5588,S,Uncharacterized conserved protein,5,0,1,24,30
COG5589,S,Uncharacterized conserved protein,0,1,0,0,1
COG5590,S,Uncharacterized conserved protein,0,0,0,0,0
COG5591,S,Uncharacterized conserved protein,0,1,0,0,1
COG5592,S,Uncharacterized conserved protein,0,0,0,0,0
COG5593,J,Nucleic-acid-binding protein possibly involved in ribosomal biogenesis,0,0,0,0,0
COG5594,S,Uncharacterized integral membrane protein,0,0,0,0,0
COG5595,R,"Zn-ribbon-containing, possibly nucleic-acid-binding protein",0,0,0,0,0
COG5596,O,"Mitochondrial import inner membrane translocase, subunit TIM22",0,0,0,0,0
COG5597,M,Alpha-N-acetylglucosamine transferase,0,0,0,0,0
COG5598,H,Trimethylamine:corrinoid methyltransferase,0,0,0,2,2
COG5599,T,Protein tyrosine phosphatase,0,0,0,0,0
COG5600,L,Transcription-associated recombination protein,0,0,0,0,0
COG5601,K,General negative regulator of transcription subunit,0,0,0,0,0
COG5602,B,"Histone deacetylase complex, SIN3 component",0,0,0,0,0
COG5603,N,"Subunit of TRAPP, an ER-Golgi tethering complex",0,0,0,0,0
COG5604,S,Uncharacterized conserved protein,0,0,0,0,0
COG5605,S,Predicted small integral membrane protein,0,1,0,0,1
COG5606,S,Uncharacterized conserved small protein,0,1,0,0,1
COG5607,S,Uncharacterized conserved protein,0,0,0,1,1
COG5608,S,Conserved secreted protein,0,1,0,0,1
COG5609,S,Uncharacterized conserved protein,0,0,0,0,0
COG5610,R,Predicted hydrolase (HAD superfamily),0,0,0,0,0
COG5611,R,"Predicted nucleic-acid-binding protein, contains PIN domain",0,0,0,0,0
COG5612,S,Predicted integral membrane protein,0,0,0,0,0
COG5613,S,Uncharacterized conserved protein,0,0,0,0,0
COG5614,R,Bacteriophage head-tail adaptor,0,2,0,0,2
COG5615,S,Predicted integral membrane protein,0,1,0,0,1
COG5616,S,Predicted integral membrane protein,15,10,2,70,97
COG5617,S,Predicted integral membrane protein,0,0,0,0,0
COG5618,R,Predicted periplasmic lipoprotein,0,0,0,0,0
COG5619,S,Uncharacterized conserved protein,0,0,0,0,0
COG5620,S,Uncharacterized conserved protein,0,0,0,0,0
COG5621,R,Predicted secreted hydrolase,0,2,0,0,2
COG5622,N,Protein required for attachment to host cells,0,0,0,0,0
COG5623,A,"Pre-mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1",0,0,0,0,0
COG5624,K,"Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA)",0,0,0,0,0
COG5625,K,Predicted transcription regulator containing HTH domain,0,0,0,0,0
COG5626,S,Uncharacterized conserved small protein,0,1,0,0,1
COG5627,L,DNA repair protein MMS21,0,0,0,0,0
COG5628,R,Predicted acetyltransferase,0,0,0,0,0
COG5629,S,Predicted metal-binding protein,0,0,0,0,0
COG5630,E,Acetylglutamate synthase,0,0,0,0,0
COG5631,K,"Predicted transcription regulator, contains HTH domain (MarR family)",0,0,0,0,0
COG5632,M,N-acetylmuramoyl-L-alanine amidase,0,0,0,0,0
COG5633,R,Predicted periplasmic lipoprotein,0,0,0,0,0
COG5634,S,Uncharacterized conserved protein,0,0,0,1,1
COG5635,T,Predicted NTPase (NACHT family),0,0,0,0,0
COG5636,S,"Uncharacterized conserved protein, contains Zn-ribbon-like motif",0,0,0,0,0
COG5637,S,Predicted integral membrane protein,0,0,0,1,1
COG5638,S,Uncharacterized conserved protein,0,0,0,0,0
COG5639,S,Uncharacterized conserved small protein,0,0,0,0,0
COG5640,O,Secreted trypsin-like serine protease,0,0,0,0,0
COG5641,K,GATA Zn-finger-containing transcription factor,0,0,0,0,0
COG5642,S,Uncharacterized conserved protein,0,2,0,1,3
COG5643,R,Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E,0,0,0,0,0
COG5644,S,Uncharacterized conserved protein,0,0,0,0,0
COG5645,R,Predicted periplasmic lipoprotein,0,0,0,0,0
COG5646,S,Uncharacterized conserved protein,1,2,1,2,6
COG5647,O,"Cullin, a subunit of E3 ubiquitin ligase",0,0,0,0,0
COG5648,B,Chromatin-associated proteins containing the HMG domain,0,0,0,0,0
COG5649,S,Uncharacterized conserved protein,0,1,0,3,4
COG5650,S,Predicted integral membrane protein,0,0,15,1,16
COG5651,N,PPE-repeat proteins,0,0,0,0,0
COG5652,S,Predicted integral membrane protein,0,1,0,0,1
COG5653,M,Protein involved in cellulose biosynthesis (CelD),0,0,0,0,0
COG5654,S,Uncharacterized conserved protein,0,0,0,1,1
COG5655,L,Plasmid rolling circle replication initiator protein and truncated derivatives,0,0,0,0,0
COG5656,O,"Importin, protein involved in nuclear import",0,0,0,0,0
COG5657,D,CAS/CSE protein involved in chromosome segregation,0,0,0,0,0
COG5658,S,Predicted integral membrane protein,0,0,0,0,0
COG5659,L,FOG: Transposase,7,3,12,10,32
COG5660,S,Predicted integral membrane protein,0,0,0,0,0
COG5661,O,Predicted secreted Zn-dependent protease,0,0,0,0,0
COG5662,K,Predicted transmembrane transcriptional regulator (anti-sigma factor),0,2,1,0,3
COG5663,S,Uncharacterized conserved protein,0,0,0,0,0
COG5664,O,Predicted secreted Zn-dependent protease,0,0,0,0,0
COG5665,K,"CCR4-NOT transcriptional regulation complex, NOT5 subunit",0,0,0,0,0