diff --git a/src/bun.js/webcore/streams.zig b/src/bun.js/webcore/streams.zig
index 0ef0e1c315b3b6..37af891db3258c 100644
--- a/src/bun.js/webcore/streams.zig
+++ b/src/bun.js/webcore/streams.zig
@@ -3518,6 +3518,11 @@ pub const FileReader = struct {
                 if (this.nonblocking and this.file_type == .pipe) {
                     this.file_type = .nonblocking_pipe;
                 }
+
+                // ensure non blocking otherwise hangs will occur
+                if (this.nonblocking) {
+                    bun.ensureNonBlocking(fd.int());
+                }
             }
 
             this.fd = fd;
diff --git a/test/regression/issue/10080.test.ts b/test/regression/issue/10080.test.ts
new file mode 100644
index 00000000000000..6613f2ecca7403
--- /dev/null
+++ b/test/regression/issue/10080.test.ts
@@ -0,0 +1,29 @@
+import { test, expect } from "bun:test";
+import { bunEnv, bunExe, isPosix } from "harness";
+import { tmpdir } from "os";
+import { join } from "path";
+
+test.if(isPosix)("10080 - ensure nonblocking file descriptor is nonblocking in FileReader", async () => {
+  const expected = "foobar\n";
+  const filename = join(tmpdir(), "bun.test.stream." + Date.now() + ".js");
+  const contents = "for await (const line of console) {console.log(`foo${line}`)}"
+  await Bun.write(filename, contents);
+  const shellCommand = `exec &> >(${bunExe()} ${filename}); echo "bar"; while read -r line; do echo $line; done`;
+
+  const proc = Bun.spawn(["bash", "-c", shellCommand], {
+    stdin: "inherit",
+    stdout: "pipe",
+    stderr: "inherit",
+    env: bunEnv,
+  });
+  const { value }= await proc.stdout.getReader().read();
+  const output = new TextDecoder().decode(value);
+  if (output !== expected) {
+    expect(output).toEqual(expected);
+    throw new Error("Output didn't match!\n");
+  }
+
+  proc.kill(9);
+  await proc.exited;
+  expect(proc.killed).toBeTrue();
+}, 1000);