diff --git a/README.md b/README.md
index fcacca0f..0fd0f870 100644
--- a/README.md
+++ b/README.md
@@ -508,6 +508,12 @@ client = Anthropic(
 )
 ```
 
+You can also customize the client on a per-request basis by using `with_options()`:
+
+```python
+client.with_options(http_client=DefaultHttpxClient(...))
+```
+
 ### Managing HTTP resources
 
 By default the library closes underlying HTTP connections whenever the client is [garbage collected](https://docs.python.org/3/reference/datamodel.html#object.__del__). You can manually close the client using the `.close()` method if desired, or with a context manager that closes when exiting.