diff --git a/src/deadline/client/ui/dialogs/submit_job_to_deadline_dialog.py b/src/deadline/client/ui/dialogs/submit_job_to_deadline_dialog.py
index f7b463a2..30b21d1d 100644
--- a/src/deadline/client/ui/dialogs/submit_job_to_deadline_dialog.py
+++ b/src/deadline/client/ui/dialogs/submit_job_to_deadline_dialog.py
@@ -385,6 +385,9 @@ def on_submit(self):
         """
         Perform a submission when the submit button is pressed
         """
+        # Unset any cached response
+        self.create_job_response = None
+
         # Retrieve all the settings into the dataclass
         settings = self.job_settings_type()
         self.shared_job_settings.update_settings(settings)