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Instructions for installing Natron from sources on macOS

These are step-by-step instructions to compile Natron on macOS.

OS X 10.6 (a.k.a. Snow Leopard) and newer are supported when building with MacPorts, and Homebrew can be used to compile it on the latest macOS (although a few Homebrew casks have to be downgraded).

Official Natron binaries

The official Natron and plugins binaries are built using the section about MacPorts in these instructions to prepare the system, and the launchBuildMain.sh build script found in the tools/jenkins directory. The script takes care of everything, from checking out sources, to compiling and packaging.

These binaries are built on an OS X 10.9 (Mavericks) virtual machine with Xcode 6.2. Note that Mavericks can not be downloaded anymore from the 10.14 (High Sierra) App Store, so you will need to use a Mac with an older system (up to 10.13), or look for alternatives.

The build system is based on MacPorts with the custom ports found in the tools/MacPorts directory in the sources. We are not using Homebrew, because MacPorts is easier to customize.

Everything is compiled using the latest version of Clang rather than the version bundled with Xcode, in order to have full OpenMP support.

Building on a VM (Virtual Machine)

Natron can be built on a virtual machine, in order to target older versions of OS X / macOS. Due to the OS X Software License Agreement, OS X may only be virtualized on Mac hardware. The excellent blog post OS X on OS X (archive) gives all the instructions to install an OS X virtual machine.

Install Dependencies

In order to have Natron compiling, first you need to install the required libraries.

There are two exclusive options: using MacPorts or using Homebrew.

Homebrew is easier to set up than MacPorts, but cannot build universal binaries.

MacPorts

Basic Setup

You need an up to date MacPorts version. Just download it and install it from http://www.macports.org, and execute the following commands in a terminal:

sudo port selfupdate
sudo port upgrade outdated

Then, you should add the "ports" provided by Natron. Edit as root the file /opt/local/etc/macports/sources.conf (as in sudo nano /opt/local/etc/macports/sources.conf) and add the following line at the beginning, with the path to the Natron sources (yes, there are three slashes after file:):

file:///Users/your_username/path_to_sources/Natron/tools/MacPorts

Then, create the index file:

(cd /Users/your_username/path_to_sources/Natron/tools/MacPorts; portindex)

It is also recommended to add the following line to /opt/local/etc/macports/variants.conf:

-x11 +no_x11 +bash_completion +no_gnome +quartz +natron

Notes for OS X 10.6 Snow Leopard

On Snow Leopard, the +universal variant may be added to /opt/local/etc/macports/variants.conf.

The libtool that comes with OS X 10.6 Snow Leopard does not work well with clang-generated binaries, so on this system you may have to substitute it with the libtool provided by MacPort's cctools package, using sudo mv /usr/bin/libtool /usr/bin/libtool.orig; sudo mv /Developer/usr/bin/libtool /Developer/usr/bin/libtool.orig; sudo ln -s /opt/local/bin/libtool /usr/bin/libtool; sudo ln -s /opt/local/bin/libtool /Developer/usr/bin/libtool

Install Ports

Install the required packages:

sudo port -v -N install pkgconfig -universal gsed -universal gawk -universal coreutils -universal findutils -universal
sudo port -v -N install cmake -universal keychain -universal
sudo port -v -N install opencolorio -quartz -python27 -python310
sudo port -v -N install cairo -x11
sudo port -v -N install qt4-mac boost expat
sudo port -v -N install py27-pyside py310-sphinx py310-sphinx_rtd_theme
sudo port select --set python python27
sudo port select --set python2 python27
sudo port select --set python3 python310
sudo port select --set sphinx py310-sphinx

Create the file /opt/local/lib/pkgconfig/glu.pc containing GLU configuration, for example using the following comands:

sudo -s
cat > /opt/local/lib/pkgconfig/glu.pc << EOF
 prefix=/usr
 exec_prefix=\${prefix}
 libdir=\${exec_prefix}/lib
 includedir=\${prefix}/include


Name: glu
 Version: 2.0
 Description: glu
 Requires:
 Libs:
 Cflags: -I\${includedir}
EOF

If you intend to build the openfx-io plugins too, you will need these additional packages:

sudo port -v -N install x264
sudo port -v -N install libvpx +highbitdepth
sudo port -v -N install ffmpeg +gpl2 +highbitdepth +natronmini
sudo port -v -N install libraw +gpl2
sudo port -v -N install openexr
sudo port -v -N install opencolorio -quartz -python27 -python310
sudo port -v -N install openimageio +natron
sudo port -v -N install seexpr211 seexpr

and for openfx-arena (note that it installs a version of ImageMagick without support for many image I/O libraries):

sudo port -v -N install librsvg -quartz
sudo port -v -N install ImageMagick +natron -x11
sudo port -v -N install poppler
sudo port -v -N install librevenge
sudo port -v -N install libcdr-0.1
sudo port -v -N install libzip
sudo sed -i -e s/Zstd::Zstd/zstd/ /opt/local/lib/pkgconfig/libzip.pc
sudo port -v -N install sox

and for openfx-gmic:

sudo port -v -N install fftw-3

Homebrew

Install Homebrew from http://brew.sh/

Qt5

Install Qt5

brew install qt@5 pyside@2
# compilation doesn't work with Qt6 linked)
brew unlink qt
# Fix the pkg-config files
brew install gnu-sed
gsed -e s@libdir=lib@libdir=\${prefix}/lib@ -i /usr/local/opt/pyside\@2/lib/pkgconfig/pyside2.pc
gsed -e s@libdir=lib@libdir=\${prefix}/lib@ -i /usr/local/opt/pyside\@2/lib/pkgconfig/shiboken2.pc

Python2 (optional)

Install Python 2.7 (yes, we know it's deprecated).

brew uninstall python@2 || true
cp tools/homebrew/python@2.rb $( brew --prefix )/Homebrew/Library/Taps/homebrew/homebrew-core/Formula/python@2.rb
brew install -s python@2

Do do the following if the homebrew.pth file does not exist:

mkdir -p ~/Library/Python/2.7/lib/python/site-packages
echo 'import site; site.addsitedir("/usr/local/lib/python2.7/site-packages")' >> ~/Library/Python/2.7/lib/python/site-packages/homebrew.pth
sudo ln -s ~/Library/Python/2.7/lib/python/site-packages/homebrew.pth /Library/Python/2.7/lib/python/site-packages/homebrew.pth

Qt4 (optional)

Qt 4 is not supported in Homebrew. Please enable the community-maintained recipe using:

brew tap cartr/qt4

Optional: Patch the qt4 recipe to fix the stack overflow issue (see QTBUG-49607, Homebrew issue #46307, MacPorts ticket 49793).

Patching a Homebrew recipe is explained in the Homebrew FAQ.

brew edit cartr/qt4/qt@4
brew install cartr/qt4/qt@4 cartr/qt4/shiboken@1.2 cartr/qt4/pyside@1.2 cartr/qt4/pyside-tools@1.2

and before the line that starts with head, add the following code:

  patch :p0 do
    # bugreports.qt.io may go away, use our local copy.
    # url "https://bugreports.qt.io/secure/attachment/52520/patch-qthread-stacksize.diff"
    # sha256 "477630235eb5ee34ed04e33f156625d1724da290e7a66b745611fb49d17f1347"
    url "https://raw.githubusercontent.com/NatronGitHub/Natron/ff4b3afd3a784f1517002bd82e2da441265385ad/tools/MacPorts/aqua/qt4-mac/files/patch-qthread-stacksize.diff"
    sha256 "a3363ff6460fb4cb4a2a311dbc0724fc5de39d22eb6fa1ec1680d6bd28d01ee4"
  end

  patch :p0 do
    url "https://raw.githubusercontent.com/NatronGitHub/Natron/ff4b3afd3a784f1517002bd82e2da441265385ad/tools/MacPorts/aqua/qt4-mac/files/patch-qt-custom-threadpool.diff"
    sha256 "470c8bf6fbcf01bd15210aad961a476abc73470e201ccb4d62a7c579452de371"
  end

Reinstall Qt4 from source (takes a while):

brew reinstall -s cartr/qt4/qt@4

Other dependencies

Install libraries:

brew install cairo expat
brew install gnu-sed gawk coreutils findutils
brew install cmake keychain sphinx-doc
/usr/local/opt/sphinx-doc/libexec/bin/pip3 install sphinx_rtd_theme
brew install pyside@1.2 pyside-tools@1.2

If compiling with Qt5:

brew install pyside@2

To install the openfx-io and openfx-misc sets of plugin, you also need the following:

brew install ilmbase openexr freetype fontconfig ffmpeg
brew unlink openimageio || true;
brew unlink opencolorio || true;
brew unlink seexpr || true;
cp tools/homebrew/opencolorio@1.rb $( brew --prefix )/Homebrew/Library/Taps/homebrew/homebrew-core/Formula
cp tools/homebrew/seexpr@2.rb $( brew --prefix )/Homebrew/Library/Taps/homebrew/homebrew-core/Formula
brew install -s opencolorio@1
brew unlink qt@4
brew install -s seexpr@2
brew link qt@4
brew install opencolorio openimageio seexpr

To install the openfx-arena set of plugin, you also need the following:

brew install librsvg poppler librevenge libcdr libzip sox
brew uninstall imagemagick
brew install imagemagick --with-hdri --with-librsvg --with-quantum-depth-32 --with-pango

To install the openfx-gmic set of plugin, you also need the following:

brew install fftw

also set the correct value for the pkg-config path (you can also put this in your .bash_profile):

export PKG_CONFIG_PATH=/usr/local/lib/pkgconfig:/opt/X11/lib/pkgconfig:/usr/local/opt/cairo/lib/pkgconfig:/usr/local/opt/icu4c/lib/pkgconfig:/usr/local/opt/libffi/lib/pkgconfig:/usr/local/opt/libxml2/lib/pkgconfig:/usr/local/opt/curl/lib/pkgconfig

Installing manually (outside of MacPorts or Homebrew) a patched Qt to avoid stack overflows

The following is not necessary if a patched Qt was already installed by the standard MacPorts or Homebrew procedures above.

See QTBUG-49607, Homebrew issue #46307, MacPorts ticket 49793.

wget https://download.qt.io/official_releases/qt/4.8/4.8.7/qt-everywhere-opensource-src-4.8.7.tar.gz
tar zxvf qt-everywhere-opensource-src-4.8.7.tar.gz
cd qt-everywhere-opensource-src-4.8.7
wget https://raw.githubusercontent.com/Homebrew/patches/480b7142c4e2ae07de6028f672695eb927a34875/qt/el-capitan.patch
patch -p1 < el-capitan.patch
wget https://bugreports.qt.io/secure/attachment/52520/patch-qthread-stacksize.diff
patch -p0 < patch-qthread-stacksize.diff

Then, configure using:

./configure -prefix /opt/qt4 -pch -system-zlib -qt-libtiff -qt-libpng -qt-libjpeg -confirm-license -opensource -nomake demos -nomake examples -nomake docs -cocoa -fast -release
  • On OS X >= 10.9 add -platform unsupported/macx-clang-libc++
  • On OS X < 10.9, to compile with clang add -platform unsupported/macx-clang
  • If compiling with gcc/g++, make sure that g++ --versionrefers to Apple's gcc >= 4.2 or clang >= 318.0.61
  • To use another openssl than the system (mainly for security reasons), add -openssl-linked -I /usr/local/Cellar/openssl/1.0.2d_1/include -L /usr/local/Cellar/openssl/1.0.2d_1/lib (where the path is changed to your openssl installation).

Then, compile using:

make

And install (after making sure /opt/qt4 is user-writable) using:

make install

Checkout sources

git clone https://github.com/NatronGitHub/Natron.git
cd Natron

If you want to compile the bleeding edge version, use the master branch:

git checkout master

Update the submodules:

git submodule update -i --recursive

Download OpenColorIO-Configs

In the past, OCIO configs were a submodule, though due to the size of the repository, we have chosen instead to make a tarball release and let you download it here. Place it at the root of Natron source tree:

curl -k -L https://github.com/NatronGitHub/OpenColorIO-Configs/archive/Natron-v2.5.tar.gz | tar zxf -
mv OpenColorIO-Configs-Natron-v2.5 OpenColorIO-Configs

Building with qmake (for Qt4 and Qt5)

Add the config.pri file

You have to define the locations of the required libraries. This is done by creating a .pri file that will tell the .pro where to find those libraries. The only library to put in the config.pri file on unix systems is boost. For all other libraries are found with PKGConfig.

  • create the config.pri file next to the Project.pro file.

You can fill it with the following proposed code to point to the libraries. Of course you need to provide valid paths that are valid on your system.

INCLUDEPATH is the path to the include files

LIBS is the path to the libs

If you installed libraries using MacPorts, use the following config.pri:

# copy and paste the following in a terminal
cp config-macports.pri config.pri

If you installed libraries using Homebrew, use the following config.pri:

# copy and paste the following in a terminal
cp config-homebrew.pri config.pri

Then check at the top of the config.pri file that the HOMEBREW variable is set to the homebrew installation prefix (usually /opt/homebrew).

Build with Makefile

You can generate a makefile by opening a Terminal, setting the current directory to the toplevel source directory, and typing

qmake -r

then type

make

This will create all binaries in all the subprojects folders.

If you want to build in DEBUG mode change the qmake call to this line:

qmake -r CONFIG+=debug

  • You can also enable logging by adding CONFIG+=log

  • You can also enable clang sanitizer by adding CONFIG+=sanitizer

Building with OpenMP support using clang

It is possible to build Natron using clang (version 3.8 is required, version 9.0 is recommended) with OpenMP support on MacPorts (or Homebrew for OS X 10.9 or later). OpenMP brings speed improvements in the tracker and in CImg-based plugins.

First, install clang 9.0. On OS X 10.9 and later with MacPorts, simply execute:

sudo port -v install clang-9.0

Or with Homebrew:

brew install llvm

On older systems, follow the procedure described in "[https://trac.macports.org/wiki/LibcxxOnOlderSystems](Using libc++ on older system)", and install and set clang-9.0 as the default compiler in the end. Note that we noticed clang 3.9.1 generates wrong code with -Os when compiling openexr (later clang versions were not checked), so it is safer to also change default configure.optflags {-Os} to default configure.optflags {-O2} in /opt/local/libexec/macports/lib/port1.0/portconfigure.tcl (type sudo nano /opt/local/libexec/macports/lib/port1.0/portconfigure.tcl to edit it).

The libtool that comes with OS X 10.6 does not work well with clang-generated binaries, and you may have to sudo mv /usr/bin/libtool /usr/bin/libtool.orig; sudo mv /Developer/usr/bin/libtool /Developer/usr/bin/libtool.orig; sudo ln -s /opt/local/bin/libtool /usr/bin/libtool; sudo ln -s /opt/local/bin/libtool /Developer/usr/bin/libtool

Then, configure using the following qmake command on MacPorts:

/opt/local/libexec/qt4/bin/qmake QMAKE_CXX='clang++-mp-9.0 -stdlib=libc++' QMAKE_CC=clang-mp-9.0 QMAKE_OBJECTIVE_CXX='clang++-mp-9.0 -stdlib=libc++' QMAKE_OBJECTIVE_CC='clang-mp-9.0 -stdlib=libc++' QMAKE_LD='clang++-mp-9.0 -stdlib=libc++' -r CONFIG+=openmp CONFIG+=enable-osmesa CONFIG+=enable-cairo

Or on Homebrew with Qt4/PySide from cartr/qt4:

QT_INSTALL_PREFIX=/usr/local
qmake=$QT_INSTALL_PREFIX/bin/qmake
env PKG_CONFIG_PATH=/usr/local/lib/pkgconfig:/opt/X11/lib/pkgconfig:/usr/local/opt/cairo/lib/pkgconfig:/usr/local/opt/icu4c/lib/pkgconfig:/usr/local/opt/libffi/lib/pkgconfig:/usr/local/opt/libxml2/lib/pkgconfig:/usr/local/opt/expat/lib/pkgconfig $qmake -spec macx-xcode CONFIG+=debug CONFIG+=enable-cairo CONFIG+=enable-osmesa CONFIG+=python3 CONFIG+=sdk_no_version_check CONFIG+=openmp -r

Or on Homebrew with Qt5/PySide2:

QT_INSTALL_PREFIX=/usr/local/opt/qt@5
qmake=$QT_INSTALL_PREFIX/bin/qmake
env PKG_CONFIG_PATH=/usr/local/lib/pkgconfig:/opt/X11/lib/pkgconfig:/usr/local/opt/cairo/lib/pkgconfig:/usr/local/opt/icu4c/lib/pkgconfig:/usr/local/opt/libffi/lib/pkgconfig:/usr/local/opt/libxml2/lib/pkgconfig:/usr/local/opt/expat/lib/pkgconfig:/usr/local/opt/qt@5/lib/pkgconfig:/usr/local/opt/pyside@2/lib/pkgconfig $qmake -spec macx-xcode CONFIG+=debug CONFIG+=enable-cairo CONFIG+=enable-osmesa CONFIG+=python3 CONFIG+=sdk_no_version_check CONFIG+=openmp -r

To build the plugins, use the following command-line:

make CXX='clang++-mp-9.0 -stdlib=libc++' OPENMP=1

Or, if you have MangledOSMesa32 installed in OSMESA_PATH and LLVM installed in LLVM_PATH (MangledOSMesa32 and LLVM build script is available from https://github.com/devernay/osmesa-install :

OSMESA_PATH=/opt/osmesa
LLVM_PATH=/opt/llvm
make CXX='clang++-mp-9.0 -stdlib=libc++' OPENMP=1 CXXFLAGS_MESA="-DHAVE_OSMESA" LDFLAGS_MESA="-L${OSMESA_PATH}/lib -lMangledOSMesa32 `${LLVM_PATH}/bin/llvm-config --ldflags --libs engine mcjit mcdisassembler | tr '\n' ' '`" OSMESA_PATH="${OSMESA_PATH}"

Build on Xcode

Follow the instruction of build but add -spec macx-xcode to the qmake call command:

qmake -r -spec macx-xcode

Then open the already provided Project-xcode.xcodeproj and compile the target "all"

Compiling plugins with Xcode

The source distributions of the plugin sets openfx-io and openfx-misc contain Xcode projects, but these require setting a few global variables in Xcode. These variables can be used to switch between the system-installed version of a package and a custom install (e.g. if you need to debug something that happens in OpenImageIO).

In Xcode Preferences, select "Locations", then "Source Trees", and add the following variable names/values (Xcode may need to be restarted after setting these):

  • LOCAL: /usr/local on Homebrew, /opt/local on MacPorts
  • BOOST_PATH: $(LOCAL)/include
  • EXR_PATH: $(LOCAL)
  • FFMPEG_PATH: $(LOCAL)
  • OCIO_PATH: $(LOCAL)
  • OIIO_PATH: $(LOCAL)
  • OPENCV_PATH: $(LOCAL)
  • SEEXPR_PATH: $(LOCAL)

It is also recommended in Xcode Preferences, select "Locations", then "Locations", to set the Derived Data location to be Relative, and in the advanced settings to set the build location to Legacy (if not, build files are somewhere under ~/Library/Developer/Xcode.

Build on Xcode with openmp clang

See instructions under "Using clang-omp with Xcode" at the following page https://clang-omp.github.io

On Macports clang now ships with openmp by default. To install it:

sudo port install clang-9.0

In your config.pri file, add the following lines and change the paths according to your installation of clang

openmp {
INCLUDEPATH += /opt/local/include/libomp
LIBS += -L/opt/local/lib/libomp -liomp5 # may also be -lomp

cc_setting.name = CC
cc_setting.value = /opt/local/bin/clang-mp-9.0
cxx_setting.name = CXX
cxx_setting.value = /opt/local/bin/clang++-mp-9.0 -stdlib=libc++
ld_setting.name = LD
ld_setting.value = /opt/local/bin/clang-mp-9.0
ldplusplus_setting.name = LDPLUSPLUS
ldplusplus_setting.value = /opt/local/bin/clang++-mp-9.0 -stdlib=libc++
QMAKE_MAC_XCODE_SETTINGS += cc_setting cxx_setting ld_setting ldplusplus_setting
QMAKE_LFLAGS += "-B /usr/bin"
}

The qmake call should add CONFIG+=openmp

qmake -r -spec macx-xcode CONFIG+=debug CONFIG+=enable-osmesa LLVM_PATH=/opt/llvm OSMESA_PATH=/opt/osmesa CONFIG+=openmp QMAKE_CXX='clang++-mp-9.0 -stdlib=libc++' QMAKE_CC=clang-mp-9.0 QMAKE_OBJECTIVE_CXX='clang++-mp-9.0 -stdlib=libc++' QMAKE_OBJECTIVE_CC='clang-mp-9.0 -stdlib=libc++' QMAKE_LD='clang++-mp-9.0 -stdlib=libc++' -r CONFIG+=openmp CONFIG+=enable-osmesa CONFIG+=enable-cairo

Then you can just build and run using Xcode

Xcode caveats

Whenever the .pro files change, Xcode will try to launch qmake and probably fail because it doesn't find the necessary binaries (qmake, moc, pkg-config, python3-config, etc.). In this case, just open a Terminal and relaunch the above command. This will rebuild the Xcode projects.

Alternatively, you can globally add the necessary directories (/usr/local/binon Homebrew, /opt/local/bin on MacPorts) to you PATH (see http://www.emacswiki.org/emacs/EmacsApp for instructions).

On MacPorts, this would look like:

launchctl setenv PATH /opt/local/bin:/opt/local/sbin:/usr/bin:/bin:/usr/sbin:/sbin

Building with cmake (Qt5 only)

On homebrew

mkdir build
cd build
cmake .. -DCMAKE_PREFIX_PATH="/opt/homebrew/opt/expat;/opt/homebrew/opt/qt@5;/opt/homebrew/opt/pyside@2" -DPYTHON_FRAMEWORK_LIBRARIES=/opt/homebrew/Frameworks/Python.framework/Versions/3.9/lib
make -j

Testing

(cd Tests && qmake -r CONFIG+=debug CONFIG+=coverage && make -j4 && ./Tests)

Generating Python bindings

This is not required as file generation occurs during build with Qt5 and generated files are already in the repository for Qt4. You would need to run it if you were both under Qt4 and either extend or modify the Python bindings via the typesystem.xml file. See the documentation of shiboken-2.7 for an explanation of the command line arguments.

On MacPorts with qt4-mac, py310-pyside, py310-shiboken:

PYVER=3.10 # Set to the python version
QT_VERSION_MAJOR=4
rm Engine/Qt${QT_VERSION_MAJOR}/NatronEngine/* Gui/Qt${QT_VERSION_MAJOR}/NatronGui/*

shiboken-${PYVER} --avoid-protected-hack --enable-pyside-extensions --include-paths=../Engine:../Global:/opt/local/include:/opt/local/include/PySide-${PYVER}  --typesystem-paths=/opt/local/share/PySide-${PYVER}/typesystems --output-directory=Engine/Qt${QT_VERSION_MAJOR} Engine/Pyside_Engine_Python.h  Engine/typesystem_engine.xml

shiboken-${PYVER} --avoid-protected-hack --enable-pyside-extensions --include-paths=../Engine:../Gui:../Global:/opt/local/include:/opt/local/include/PySide-${PYVER}  --typesystem-paths=/opt/local/share/PySide-${PYVER}/typesystems:Engine:Shiboken --output-directory=Gui/Qt${QT_VERSION_MAJOR} Gui/Pyside_Gui_Python.h  Gui/typesystem_natronGui.xml

tools/utils/runPostShiboken.sh Engine/Qt${QT_VERSION_MAJOR}/NatronEngine natronengine
tools/utils/runPostShiboken.sh Gui/Qt${QT_VERSION_MAJOR}/NatronGui natrongui

Building Natron with Qt5 should generate the Python bindings automatically, but in case it does not, here are the commands to recreate the Python bindings:

On MacPorts with qt5, py310-pyside2:

PYVER=3.10 # Set to the python version
PYTHON_HOME=$(python${PYVER}-config --prefix)
QT_VERSION_MAJOR=5
# Fix a missing link in the MacPorts package
[ ! -f ${PYTHON_HOME}/lib/python${PYVER}/site-packages/shiboken2_generator/shiboken2-${PYVER} ] && sudo ln -s shiboken2 ${PYTHON_HOME}/lib/python${PYVER}/site-packages/shiboken2_generator/shiboken2-${PYVER}

rm Engine/Qt${QT_VERSION_MAJOR}/NatronEngine/* Gui/Qt${QT_VERSION_MAJOR}/NatronGui/*
# ${PYTHON_HOME}/lib/python${PYVER}/site-packages/PySide2/include
shiboken2-${PYVER} --avoid-protected-hack --enable-pyside-extensions --include-paths=.:Engine:Global:libs/OpenFX/include:/opt/local/include:/opt/local/libexec/qt${QT_VERSION_MAJOR}/include:${PYTHON_HOME}/include/python${PYVER}:${PYTHON_HOME}/lib/python${PYVER}/site-packages/PySide2/include --typesystem-paths=${PYTHON_HOME}/lib/python${PYVER}/site-packages/PySide2/typesystems --output-directory=Engine/Qt${QT_VERSION_MAJOR} Engine/Pyside2_Engine_Python.h  Engine/typesystem_engine.xml

shiboken2-${PYVER} --avoid-protected-hack --enable-pyside-extensions --include-paths=.:Engine:Global:libs/OpenFX/include:/opt/local/include:/opt/local/libexec/qt${QT_VERSION_MAJOR}/include:/opt/local/libexec/qt${QT_VERSION_MAJOR}/include/QtWidgets:${PYTHON_HOME}/include/python${PYVER}:${PYTHON_HOME}/lib/python${PYVER}/site-packages/PySide2/include --typesystem-paths=${PYTHON_HOME}/lib/python${PYVER}/site-packages/PySide2/typesystems:Engine:Shiboken --output-directory=Gui/Qt${QT_VERSION_MAJOR} Gui/Pyside2_Gui_Python.h  Gui/typesystem_natronGui.xml

tools/utils/runPostShiboken2.sh Engine/Qt${QT_VERSION_MAJOR}/NatronEngine natronengine
tools/utils/runPostShiboken2.sh Gui/Qt${QT_VERSION_MAJOR}/NatronGui natrongui

on HomeBrew with Qt5/PySide2/Shiboken2:

PYVER=3.10 # Set to the python version
export PATH="/usr/local/opt/pyside@2/bin:$PATH"
QT_VERSION_MAJOR=5
rm Engine/Qt${QT_VERSION_MAJOR}/NatronEngine/* Gui/Qt${QT_VERSION_MAJOR}/NatronGui/*

shiboken2 --enable-parent-ctor-heuristic --use-isnull-as-nb_nonzero --avoid-protected-hack --enable-pyside-extensions --include-paths=.:Global:Engine:libs/OpenFX/include:/usr/local/Frameworks/Python.framework/Versions/${PYVER}/include/python${PYVER}:/usr/local/include:/usr/local/opt/pyside@2/include/PySide2:/usr/local/opt/qt@${QT_VERSION_MAJOR}/include  --typesystem-paths=/usr/local/opt/pyside@2/share/PySide2/typesystems --output-directory=Engine/Qt${QT_VERSION_MAJOR} Engine/PySide2_Engine_Python.h  Engine/typesystem_engine.xml

shiboken2 --enable-parent-ctor-heuristic --use-isnull-as-nb_nonzero --avoid-protected-hack --enable-pyside-extensions --include-paths=.:Global:Engine:Gui:libs/OpenFX/include:/usr/local/Frameworks/Python.framework/Versions/${PYVER}/include/python${PYVER}:/usr/local/include:/usr/local/opt/pyside@2/include/PySide2:/usr/local/opt/qt@${QT_VERSION_MAJOR}/include:/usr/local/opt/qt@5/include/QtWidgets  --typesystem-paths=/usr/local/opt/pyside@2/share/PySide2/typesystems:Engine --output-directory=Gui/Qt${QT_VERSION_MAJOR} Gui/PySide2_Gui_Python.h  Gui/typesystem_natronGui.xml

tools/utils/runPostShiboken2.sh Engine/Qt${QT_VERSION_MAJOR}/NatronEngine natronengine
tools/utils/runPostShiboken2.sh Gui/Qt${QT_VERSION_MAJOR}/NatronGui natrongui

Note Shiboken has a few glitches which needs fixing with some sed commands, run tools/utils/runPostShiboken.sh once shiboken is called

OpenFX plugins

Instructions to build the openfx-io and openfx-misc sets of plugins can also be found in the tools/packageOSX.sh script if you are using MacPorts, or in the .travis.yml file in their respective github repositories if you are using Homebrew (openfx-misc/.travis.yml, openfx-io/.travis.yml.

You can install TuttleOFX using Homebrew:

brew tap homebrew/science homebrew/x11 homebrew/python cbenhagen/video
brew install tuttleofx

Or have a look at the instructions for building on MacPorts as well as precompiled universal binaries.