diff --git a/.test_suite.sh b/.test_suite.sh
index 804d1e8c..cbb4c1f7 100755
--- a/.test_suite.sh
+++ b/.test_suite.sh
@@ -26,6 +26,11 @@ testSliceMultipleRegions() {
     assertEquals 0 $?
 }
 
+testSliceMultipleRegionsBed() {
+    assertEquals "156" `./build/sambamba slice -L test/chr2_chr3_test_region.bed test/issue_204.bam |\
+      ./build/sambamba view -c /dev/stdin`
+}
+
 testView() {
     assertEquals "1806" `./build/sambamba view -c ex1_header.sorted.bam chr2`
     assertEquals "1464" `./build/sambamba view -c ex1_header.sorted.bam chr1`
diff --git a/sambamba/slice.d b/sambamba/slice.d
index d896553e..ee21313d 100644
--- a/sambamba/slice.d
+++ b/sambamba/slice.d
@@ -35,6 +35,7 @@ import std.parallelism;
 import std.conv;
 import std.stdio;
 import std.exception;
+import sambamba.utils.common.bed;
 
 import sambamba.utils.common.overwrite;
 
@@ -167,6 +168,7 @@ void fetchRegions(BamReader bam, Region[] regions, ref Stream stream)
         // write R1
         foreach (read; r1.data)
             writer.writeRecord(read);
+        // Flush the BamWriter before our copyAsIs call.
         writer.flush();
 
         copyAsIs(bam, stream, s2_start_offset, s2_end_offset);
@@ -271,6 +273,8 @@ void printUsage()
     stderr.writeln();
     stderr.writeln("OPTIONS: -o, --output-filename=OUTPUT_FILENAME");
     stderr.writeln("            output BAM filename");
+    stderr.writeln("         -L, --regions=FILENAME");
+    stderr.writeln("            output only reads overlapping one of regions from the BED file");
 }
 
 version(standalone) {
@@ -283,17 +287,30 @@ int slice_main(string[] args) {
 
     // at least two arguments must be presented
     string output_filename = null;
+    string bed_filename = null;
 
     try {
         getopt(args,
                std.getopt.config.caseSensitive,
-               "output-filename|o", &output_filename);
+               "output-filename|o", &output_filename,
+               "regions|L",         &bed_filename);
 
-        if (args.length < 3) {
+        // Check that an input file was specified.
+        if (args.length < 2) {
             printUsage();
             return 0;
         }
 
+        // Either a bed file or a set of regions needs to be specified.
+        if (bed_filename is null && args.length < 3) {
+            throw new Exception("Must provide either a bed file or list of regions.");
+        }
+        
+        // But you can't provide both a bed file AND a set of regions.
+        if (bed_filename.length > 0 && args.length > 2) {
+            throw new Exception("specifying both region and BED filename is disallowed");
+        }
+
         protectFromOverwrite(args[1], output_filename);
 
         import std.parallelism;
@@ -318,10 +335,16 @@ int slice_main(string[] args) {
             stream = new undead.stream.BufferedFile(handle, FileMode.Out, BUFSIZE);
         }
 
-        if (args[2] == "*") {
+        if (bed_filename is null && args[2] == "*") {
             fetchUnmapped(bam, stream);
         } else {
-            auto regions = map!parseRegion(args[2 .. $]).array;
+            Region[] regions;
+            if (bed_filename !is null) {
+                auto bam_regions = parseBed(bed_filename, bam);
+                regions = bam_regions.map!(r => Region(bam.reference(r.ref_id).name, r.start, r.end)).array;
+            } else {
+                regions = map!parseRegion(args[2 .. $]).array;
+            }
             fetchRegions(bam, regions, stream);
         }
 
diff --git a/test/chr2_chr3_test_region.bed b/test/chr2_chr3_test_region.bed
new file mode 100644
index 00000000..e04ed519
--- /dev/null
+++ b/test/chr2_chr3_test_region.bed
@@ -0,0 +1,4 @@
+2	166860000	166870000
+2	166875000	166890000
+3	100000000	170000000
+3	150000000	200000000