diff --git a/cranelift/codegen/src/isa/aarch64/lower/isle.rs b/cranelift/codegen/src/isa/aarch64/lower/isle.rs
index b08d3cd173f9..24e4ade82428 100644
--- a/cranelift/codegen/src/isa/aarch64/lower/isle.rs
+++ b/cranelift/codegen/src/isa/aarch64/lower/isle.rs
@@ -152,14 +152,17 @@ where
                         let imm =
                             MoveWideConst::maybe_with_shift(((!imm16) & 0xffff) as u16, i * 16)
                                 .unwrap();
-                        self.emitted_insts.push(MInst::MovN { rd, imm, size });
+                        self.emitted_insts
+                            .push((MInst::MovN { rd, imm, size }, false));
                     } else {
                         let imm = MoveWideConst::maybe_with_shift(imm16 as u16, i * 16).unwrap();
-                        self.emitted_insts.push(MInst::MovZ { rd, imm, size });
+                        self.emitted_insts
+                            .push((MInst::MovZ { rd, imm, size }, false));
                     }
                 } else {
                     let imm = MoveWideConst::maybe_with_shift(imm16 as u16, i * 16).unwrap();
-                    self.emitted_insts.push(MInst::MovK { rd, imm, size });
+                    self.emitted_insts
+                        .push((MInst::MovK { rd, imm, size }, false));
                 }
             }
         }
@@ -200,7 +203,7 @@ where
     }
 
     fn emit(&mut self, inst: &MInst) -> Unit {
-        self.emitted_insts.push(inst.clone());
+        self.emitted_insts.push((inst.clone(), false));
     }
 
     fn cond_br_zero(&mut self, reg: Reg) -> CondBrKind {
diff --git a/cranelift/codegen/src/isa/s390x/lower/isle.rs b/cranelift/codegen/src/isa/s390x/lower/isle.rs
index 0a7363962702..a40679106aa2 100644
--- a/cranelift/codegen/src/isa/s390x/lower/isle.rs
+++ b/cranelift/codegen/src/isa/s390x/lower/isle.rs
@@ -469,6 +469,6 @@ where
 
     #[inline]
     fn emit(&mut self, inst: &MInst) -> Unit {
-        self.emitted_insts.push(inst.clone());
+        self.emitted_insts.push((inst.clone(), false));
     }
 }
diff --git a/cranelift/codegen/src/isa/x64/lower/isle.rs b/cranelift/codegen/src/isa/x64/lower/isle.rs
index 1f1bcb32d506..c6bd7651b413 100644
--- a/cranelift/codegen/src/isa/x64/lower/isle.rs
+++ b/cranelift/codegen/src/isa/x64/lower/isle.rs
@@ -227,7 +227,7 @@ where
 
     fn emit(&mut self, inst: &MInst) -> Unit {
         for inst in inst.clone().mov_mitosis() {
-            self.emitted_insts.push(inst);
+            self.emitted_insts.push((inst, false));
         }
     }
 
diff --git a/cranelift/codegen/src/machinst/isle.rs b/cranelift/codegen/src/machinst/isle.rs
index d7d1fae60a4f..369f3d1f6616 100644
--- a/cranelift/codegen/src/machinst/isle.rs
+++ b/cranelift/codegen/src/machinst/isle.rs
@@ -299,12 +299,12 @@ macro_rules! isle_prelude_methods {
 /// internally has a temporary reference to a machinst `LowerCtx`.
 pub(crate) struct IsleContext<'a, C: LowerCtx, F, I, const N: usize>
 where
-    [C::I; N]: smallvec::Array,
+    [(C::I, bool); N]: smallvec::Array,
 {
     pub lower_ctx: &'a mut C,
     pub flags: &'a F,
     pub isa_flags: &'a I,
-    pub emitted_insts: SmallVec<[C::I; N]>,
+    pub emitted_insts: SmallVec<[(C::I, bool); N]>,
 }
 
 /// Shared lowering code amongst all backends for doing ISLE-based lowering.
@@ -323,7 +323,7 @@ pub(crate) fn lower_common<C, F, I, const N: usize>(
 ) -> Result<(), ()>
 where
     C: LowerCtx,
-    [C::I; N]: smallvec::Array<Item = C::I>,
+    [(C::I, bool); N]: smallvec::Array<Item = (C::I, bool)>,
 {
     // TODO: reuse the ISLE context across lowerings so we can reuse its
     // internal heap allocations.
@@ -367,7 +367,7 @@ where
             renamer.add_rename(*temp, dst.to_reg(), *ty);
         }
     }
-    for inst in isle_ctx.emitted_insts.iter_mut() {
+    for (inst, _) in isle_ctx.emitted_insts.iter_mut() {
         map_regs(inst, &renamer);
     }
 
@@ -387,8 +387,12 @@ where
     // Once everything is remapped we forward all emitted instructions to the
     // `lower_ctx`. Note that this happens after the synthetic mov's above in
     // case any of these instruction use those movs.
-    for inst in isle_ctx.emitted_insts {
-        lower_ctx.emit(inst);
+    for (inst, is_safepoint) in isle_ctx.emitted_insts {
+        if is_safepoint {
+            lower_ctx.emit_safepoint(inst);
+        } else {
+            lower_ctx.emit(inst);
+        }
     }
 
     Ok(())