diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 59f4d55..dd67298 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -5,20 +5,17 @@ on: [push, pull_request]
 
 jobs:
   build:
-    name: build (Python ${{ matrix.python-version }}, Django ${{ matrix.django-version }})
+    name: |
+      build (Python ${{ matrix.python-version }}, Django ${{ matrix.django-version }}, ${{ matrix.database-engine }})
     runs-on: ubuntu-latest
 
     strategy:
       fail-fast: false
       matrix:
-        python-version: ['3.11', '3.12']
-        django-version: ['4.2', '5.0', 'dev']
+        python-version: ['3.12']
+        django-version: ['4.2', '5.1', 'dev']
+        database-engine: ["mysql", "postgres"]
 
-        exclude:
-          - python-version: '3.12'
-            django-version: '4.2'
-          - python-version: '3.11'
-            django-version: 'dev'
     services:
       mysql:
         image: mysql:latest
@@ -28,6 +25,17 @@ jobs:
         ports:
           - 3306:3306
         options: --health-cmd="mysqladmin ping" --health-interval=10s --health-timeout=5s --health-retries=3
+      postgres:
+        image: postgres:latest
+        env:
+          POSTGRES_PASSWORD: postgres
+        options: >-
+          --health-cmd pg_isready
+          --health-interval 10s
+          --health-timeout 5s
+          --health-retries 5
+        ports:
+          - 5432:5432
 
     steps:
       - name: Install pycups and words dependency
@@ -61,7 +69,6 @@ jobs:
           python -m pip install --upgrade pip
           python -m pip install -r https://raw.githubusercontent.com/clinicedc/edc/develop/requirements.tests/tox.txt
 
-
       - name: Tox tests
         run: |
           tox -v
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index a32918b..78a9907 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -3,20 +3,20 @@ exclude: tests/etc/user-*
 
 repos:
   - repo: https://github.com/PyCQA/bandit
-    rev: 1.7.7
+    rev: 1.7.9
     hooks:
       - id: bandit
         args:
           - "-x *test*.py"
 
   - repo: https://github.com/psf/black
-    rev: 24.2.0
+    rev: 24.8.0
     hooks:
       - id: black
-        language_version: python3.11
+        language_version: python3.12
 
   - repo: https://github.com/pycqa/flake8
-    rev: 7.0.0
+    rev: 7.1.1
     hooks:
       - id: flake8
         args:
@@ -28,21 +28,22 @@ repos:
       - id: isort
 
   - repo: https://github.com/pre-commit/pre-commit-hooks
-    rev: v4.5.0
+    rev: v4.6.0
     hooks:
-      - id: requirements-txt-fixer
-        files: requirements/.*\.txt$
-      - id: trailing-whitespace
       - id: check-added-large-files
-      - id: fix-byte-order-marker
       - id: check-docstring-first
       - id: check-executables-have-shebangs
       - id: check-merge-conflict
+      - id: check-toml
       - id: debug-statements
       - id: detect-private-key
+      - id: fix-byte-order-marker
+      - id: requirements-txt-fixer
+        files: requirements/.*\.txt$
+      - id: trailing-whitespace
 
   - repo: https://github.com/adrienverge/yamllint
-    rev: v1.34.0
+    rev: v1.35.1
     hooks:
       - id: yamllint
         args:
diff --git a/edc_lab/tests/test_settings.py b/edc_lab/tests/test_settings.py
new file mode 100644
index 0000000..0a85b7b
--- /dev/null
+++ b/edc_lab/tests/test_settings.py
@@ -0,0 +1,76 @@
+#!/usr/bin/env python
+import sys
+from pathlib import Path
+
+from edc_test_settings.default_test_settings import DefaultTestSettings
+
+app_name = "edc_lab"
+base_dir = Path(__file__).absolute().parent.parent.parent
+
+project_settings = DefaultTestSettings(
+    calling_file=__file__,
+    BASE_DIR=base_dir,
+    APP_NAME=app_name,
+    ETC_DIR=str(base_dir / app_name / "tests" / "etc"),
+    SILENCED_SYSTEM_CHECKS=[
+        "sites.E101",
+        "edc_navbar.E002",
+        "edc_navbar.E003",
+        "edc_consent.E001",
+    ],
+    SUBJECT_SCREENING_MODEL="lab_app.subjectscreening",
+    SUBJECT_CONSENT_MODEL="lab_app.subjectconsent",
+    SUBJECT_VISIT_MODEL="edc_visit_tracking.subjectvisit",
+    SUBJECT_VISIT_MISSED_MODEL="edc_visit_tracking.subjectvisitmissed",
+    SUBJECT_REQUISITION_MODEL="lab_app.subjectrequisition",
+    SUBJECT_APP_LABEL="lab_app",
+    INSTALLED_APPS=[
+        "django.contrib.admin",
+        "django.contrib.auth",
+        "django.contrib.contenttypes",
+        "django.contrib.sessions",
+        "django.contrib.messages",
+        "django.contrib.staticfiles",
+        "django.contrib.sites",
+        "django_crypto_fields.apps.AppConfig",
+        "django_revision.apps.AppConfig",
+        "multisite",
+        "edc_auth.apps.AppConfig",
+        "edc_action_item.apps.AppConfig",
+        "edc_appointment.apps.AppConfig",
+        "edc_adverse_event.apps.AppConfig",
+        "adverse_event_app.apps.AppConfig",
+        "edc_consent.apps.AppConfig",
+        "edc_crf.apps.AppConfig",
+        "edc_list_data.apps.AppConfig",
+        "edc_protocol.apps.AppConfig",
+        "edc_metadata.apps.AppConfig",
+        "edc_dashboard.apps.AppConfig",
+        "edc_subject_dashboard.apps.AppConfig",
+        "edc_review_dashboard.apps.AppConfig",
+        "edc_device.apps.AppConfig",
+        "edc_identifier.apps.AppConfig",
+        "edc_facility.apps.AppConfig",
+        "edc_label.apps.AppConfig",
+        "edc_model.apps.AppConfig",
+        "edc_notification.apps.AppConfig",
+        "edc_data_manager.apps.AppConfig",
+        "edc_form_runners.apps.AppConfig",
+        "edc_registration.apps.AppConfig",
+        "edc_search.apps.AppConfig",
+        "edc_sites.apps.AppConfig",
+        "edc_timepoint.apps.AppConfig",
+        "edc_visit_schedule.apps.AppConfig",
+        "edc_visit_tracking.apps.AppConfig",
+        "edc_offstudy.apps.AppConfig",
+        "edc_lab.apps.AppConfig",
+        "lab_app.apps.AppConfig",
+        "edc_appconfig.apps.AppConfig",
+    ],
+    add_dashboard_middleware=True,
+    use_test_urls=True,
+).settings
+
+
+for k, v in project_settings.items():
+    setattr(sys.modules[__name__], k, v)
diff --git a/lab_app/reference_model_configs.py b/lab_app/reference_model_configs.py
deleted file mode 100644
index 779f7b3..0000000
--- a/lab_app/reference_model_configs.py
+++ /dev/null
@@ -1,5 +0,0 @@
-from edc_reference import site_reference_configs
-
-site_reference_configs.register_from_visit_schedule(
-    visit_models={"edc_appointment.appointment": "lab_app.subjectvisit"}
-)
diff --git a/pyproject.toml b/pyproject.toml
index 2e2d5a7..a4915a2 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -6,12 +6,12 @@ version_file="_version.py"
 
 [tool.black]
 line-length = 95
-target-version = ["py311"]
+target-version = ["py312"]
 extend-exclude = '''^(.*\/)*\b(migrations)\b($|\/.*$)'''
 
 [tool.isort]
 profile = "black"
-py_version = "311"
+py_version = "312"
 skip = [".tox", ".eggs", "migrations"]
 
 [tool.coverage.run]
@@ -35,21 +35,19 @@ exclude_lines = [
 legacy_tox_ini = """
 [tox]
 envlist =
-    py{311}-dj{42,50},
-    py{312}-dj{50,dev},
+    py{312}-dj{42,51,dev},
     lint
 
 isolated_build = true
 
 [gh-actions]
 python =
-    3.11: py311
     3.12: py312, lint
 
 [gh-actions:env]
 DJANGO =
     4.2: dj42
-    5.0: dj50
+    5.1: dj51
     dev: djdev, lint
 
 [testenv]
@@ -59,11 +57,11 @@ deps =
     -r https://raw.githubusercontent.com/clinicedc/edc/develop/requirements.tests/edc.txt
     -r https://raw.githubusercontent.com/clinicedc/edc/develop/requirements.tests/third_party_dev.txt
     dj42: Django>=4.2,<5.0
-    dj50: Django>=5.0
+    dj51: Django>=5.1,<5.2
     djdev: https://github.com/django/django/tarball/main
 
 commands =
-    pip install -U pip coverage[toml]
+    pip install -U pip
     pip --version
     pip freeze
     coverage run -a runtests.py
diff --git a/runtests.py b/runtests.py
index 676f4d6..3131113 100644
--- a/runtests.py
+++ b/runtests.py
@@ -1,76 +1,5 @@
 #!/usr/bin/env python
-import logging
-from pathlib import Path
-
-from edc_test_utils import DefaultTestSettings, func_main
-
-app_name = "edc_lab"
-base_dir = Path(__file__).absolute().parent
-
-project_settings = DefaultTestSettings(
-    calling_file=__file__,
-    BASE_DIR=base_dir,
-    APP_NAME=app_name,
-    ETC_DIR=str(base_dir / app_name / "tests" / "etc"),
-    SILENCED_SYSTEM_CHECKS=[
-        "sites.E101",
-        "edc_navbar.E002",
-        "edc_navbar.E003",
-        "edc_consent.E001",
-    ],
-    SUBJECT_SCREENING_MODEL="lab_app.subjectscreening",
-    SUBJECT_CONSENT_MODEL="lab_app.subjectconsent",
-    SUBJECT_VISIT_MODEL="edc_visit_tracking.subjectvisit",
-    SUBJECT_VISIT_MISSED_MODEL="edc_visit_tracking.subjectvisitmissed",
-    SUBJECT_REQUISITION_MODEL="lab_app.subjectrequisition",
-    SUBJECT_APP_LABEL="lab_app",
-    INSTALLED_APPS=[
-        "django.contrib.admin",
-        "django.contrib.auth",
-        "django.contrib.contenttypes",
-        "django.contrib.sessions",
-        "django.contrib.messages",
-        "django.contrib.staticfiles",
-        "django.contrib.sites",
-        "django_crypto_fields.apps.AppConfig",
-        "django_revision.apps.AppConfig",
-        "multisite",
-        "edc_auth.apps.AppConfig",
-        "edc_action_item.apps.AppConfig",
-        "edc_appointment.apps.AppConfig",
-        "edc_consent.apps.AppConfig",
-        "edc_crf.apps.AppConfig",
-        "edc_list_data.apps.AppConfig",
-        "edc_protocol.apps.AppConfig",
-        "edc_metadata.apps.AppConfig",
-        "edc_device.apps.AppConfig",
-        "edc_identifier.apps.AppConfig",
-        "edc_facility.apps.AppConfig",
-        "edc_label.apps.AppConfig",
-        "edc_model.apps.AppConfig",
-        "edc_notification.apps.AppConfig",
-        "edc_data_manager.apps.AppConfig",
-        "edc_form_runners.apps.AppConfig",
-        "edc_registration.apps.AppConfig",
-        "edc_search.apps.AppConfig",
-        "edc_sites.apps.AppConfig",
-        "edc_timepoint.apps.AppConfig",
-        "edc_visit_schedule.apps.AppConfig",
-        "edc_visit_tracking.apps.AppConfig",
-        "edc_offstudy.apps.AppConfig",
-        "edc_lab.apps.AppConfig",
-        "lab_app.apps.AppConfig",
-        "edc_appconfig.apps.AppConfig",
-    ],
-    add_dashboard_middleware=True,
-    use_test_urls=True,
-).settings
-
-
-def main():
-    func_main(project_settings, f"{app_name}.tests")
-
+from edc_test_settings.func_main import func_main2
 
 if __name__ == "__main__":
-    logging.basicConfig()
-    main()
+    func_main2("edc_lab.tests.test_settings", "edc_lab.tests")
diff --git a/setup.cfg b/setup.cfg
index ad91b28..d7f2bcd 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -13,15 +13,15 @@ classifiers=
     Environment :: Web Environment
     Framework :: Django
     Framework :: Django :: 4.2
+    Framework :: Django :: 5.1
     Intended Audience :: Developers
     Intended Audience :: Science/Research
     Operating System :: OS Independent
-    Programming Language :: Python :: 3.11
+    Programming Language :: Python :: 3.12
     License :: OSI Approved :: GNU General Public License v3 (GPLv3)
 
-
 [options]
-python_requires = >=3.11
+python_requires = >=3.12
 zip_safe = False
 include_package_data = True
 packages = find: