diff --git a/requirements.txt b/requirements.txt
index 0cc54192b8..7f45fd7d27 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,4 +1,4 @@
-libusb1 == 1.6.6
+libusb1==2.0.1
 numpy==1.17.2
 hexdump>=3.3
 pycryptodome==3.9.8
diff --git a/setup.py b/setup.py
index a1272cbf75..c419056a94 100644
--- a/setup.py
+++ b/setup.py
@@ -46,7 +46,7 @@ def find_version(*file_paths):
   platforms='any',
   license='MIT',
   install_requires=[
-    'libusb1 == 1.6.6',
+    'libusb1 == 2.0.1',
     'hexdump >= 3.3',
     'pycryptodome >= 3.9.8',
     'tqdm >= 4.14.0',