MC.10+S:A435S,Orf9b:R47H (99 seqs, >10 places)

[xz-keg]

From sars-cov-2-variants/lineage-proposals#1946

MC.10+G22865T,G28423A(Orf9b:R47H,S:A435S)

GISAID query: G22865T, G28423A, C16332T
No. of seqs: 37(USA 14(AZ,CA,IA,MN,NJ,NY,TX) Canada 10(NB,ON,QC) UK 6(England, Scotland) France 3 Germany 1 Denmark 1 Netherlands 1 Singapore 1)

First: EPI_ISL_19361831, USA-MN, 2024-7-26
Latest: EPI_ISL_19423471,USA-IA, 2024-9-14

usher

[FedeGueli]

43, Slovenia

[Over-There-Is]

a branch gets S:Q173K now.

[FedeGueli]

a branch gets S:Q173K now.

Query for it: C22079A,G28423A

2 GBW samples (pooled) from two different airports collected on Sept 18 and 19.

@aviczhl2 i suggest to add to the main proposal

thx @Over-There-Is for spotting it

[xz-keg]

C22079A,G28423A

still 1 GBW-BBB seq. at least wait for a second single-patient seq.

[xz-keg]

This branch is 76 now and the fastest among KP.3.1.1-descendants. @corneliusroemer

[xz-keg]

Crazy 49% advantage against KP.3.1.1 baseline

[FedeGueli]

Crazy 49% advantage against KP.3.1.1 baseline

yeah it is the only Kp.3.1.1 that seems being close to XEC and ahead of quite everything else. Also conisdering that partly it depends by New Brunswick Canadian clusters i think it will be fast anyway

[FedeGueli]

Also to be noticed the Three GBW from two airports with further S:Q173K (one from Japan)

[FedeGueli]

77 Ohio

Ping @corneliusroemer this seems one of the few things able to compete vs XEC a designation is needed because no one is seeing it beyond the restricted variant groups.

[xz-keg]

92 seqs now

[FedeGueli]

99 Utah, Ontario, Netherlands (2 provinces), Italy

[FedeGueli]

131 due to two Canadian clusters in two different provinces

[FedeGueli]

Designated MC.10.1 via efe8e07