Tongue proposed new cell ontology terms

[olgabot]

Hello!
This discussion is to propose the free_annotation terms to the Cell Ontology so that future researchers may use your specific terms rather than the generic ones that you had to use. Below are your free_annotation terms and what I (@olgabot) thought the relationship was to the existing cell ontology term, whether it was brand new term and cell type, in which case I used is_a, or it was merely a synonym for a term that already existed in the cell ontology, in which case I used synonym.

Please comment below with what is the correct relationship between terms, or correct the term itself and I'll deal with the submission to the Cell Ontology group.

Thank you for your help!
Warmest,
Olga

For the annotations below, here is the format:

• free annotation relationship cell ontology class

Relationships could be either:

• is_a - means that the free annotation label is a new "cell type" to add to the cell ontology
• synonym - means that the free annotation label is not a new cell type, but another term for the same thing that already exists in the cell ontology

I wasn't always sure which relationship to use so please comment below and I will correct it.

Examples:

• Inhibitory neuron is_a neuron
• alveolar epithelial type 2 cells synonym type II pneumocyte

FACS and droplet free annotation tables in the "Details" below.

FACS free annotation table

tissue	cell_ontology_class	free_annotation	n_cells
Tongue	basal cell of epidermis	basal cells	729
Tongue	basal cell of epidermis	differentiating basal cells	161
Tongue	basal cell of epidermis	proliferating	196
Tongue	keratinocyte	differentiated keratinocyte	182
Tongue	keratinocyte	filiform differentiated keratinocytes	27
Tongue	keratinocyte	suprabasal differentiating keratinocytes	121

Droplet free annotation table

tissue	cell_ontology_class	free_annotation	n_cells
Tongue	basal cell of epidermis	basal cells	3345
Tongue	basal cell of epidermis	proliferating	1079
Tongue	keratinocyte	differentiated	1095
Tongue	keratinocyte	filiform differentiated	199
Tongue	keratinocyte	suprabasal differentiated	967
Tongue	keratinocyte	suprabasal differentiating	815

Proposed annotations

@melocactus

FACS

• differentiating basal cells is_a basal cell of epidermis
• differentiated keratinocyte is_a keratinocyte
• filiform differentiated keratinocyte is_a keratinocyte
• suprabasal differentiating keratinocyte is_a keratinocyte