metadata.yaml

about:
- name: Medial Temporal Lobe
  schemaKey: GenericType
- name: Medial Frontal Cortex
  schemaKey: Anatomy
access:
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  status: dandi:OpenAccess
assetsSummary:
  approach:
  - name: electrophysiological approach
    schemaKey: ApproachType
  dataStandard:
  - identifier: RRID:SCR_015242
    name: Neurodata Without Borders (NWB)
    schemaKey: StandardsType
  measurementTechnique:
  - name: surgical technique
    schemaKey: MeasurementTechniqueType
  - name: spike sorting technique
    schemaKey: MeasurementTechniqueType
  numberOfBytes: 9788560252
  numberOfFiles: 41
  numberOfSubjects: 21
  schemaKey: AssetsSummary
  species:
  - identifier: http://purl.obolibrary.org/obo/NCBITaxon_9606
    name: Homo sapiens - Human
    schemaKey: SpeciesType
  variableMeasured:
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  - ElectrodeGroup
citation: Kyzar, Michael; Kaminski, Jan; Brzezicka, Aneta; Reed, Chrystal M.; Chung,
  Jeffrey M. ; Mamelak, Adam M.; Rutishauser, Ueli (2024) Dataset of human-single
  neuron activity during a Sternberg working memory task (Version 0.240123.1806) [Data
  set]. DANDI archive. https://doi.org/10.48324/dandi.000469/0.240123.1806
contributor:
- affiliation:
  - name: Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA,
      USA
    schemaKey: Affiliation
  email: kyzarnexus@gmail.com
  identifier: 0009-0004-4392-9933
  includeInCitation: true
  name: Kyzar, Michael
  roleName:
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  - dcite:Author
  - dcite:DataCurator
  - dcite:DataManager
  - dcite:FormalAnalysis
  - dcite:Investigation
  - dcite:Maintainer
  - dcite:Methodology
  - dcite:ProjectLeader
  - dcite:ProjectManager
  - dcite:ProjectMember
  - dcite:Researcher
  - dcite:Software
  - dcite:Validation
  - dcite:Visualization
  schemaKey: Person
- affiliation: []
  identifier: 0000-0002-8663-7314
  includeInCitation: true
  name: Kaminski, Jan
  roleName: []
  schemaKey: Person
- affiliation: []
  identifier: 0000-0003-1950-4180
  includeInCitation: true
  name: Brzezicka, Aneta
  roleName:
  - dcite:Author
  - dcite:DataCollector
  schemaKey: Person
- affiliation: []
  identifier: 0000-0002-7157-3645
  includeInCitation: true
  name: Reed, Chrystal M.
  roleName: []
  schemaKey: Person
- affiliation: []
  identifier: 0000-0002-4989-0994
  includeInCitation: true
  name: 'Chung, Jeffrey M. '
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- affiliation: []
  identifier: 0000-0002-4245-6431
  includeInCitation: true
  name: Mamelak, Adam M.
  roleName: []
  schemaKey: Person
- affiliation:
  - name: Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA,
      USA
    schemaKey: Affiliation
  - name: Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
    schemaKey: Affiliation
  - name: Division of Biology and Biological Engineering, California Institute of
      Technology, Pasadena, CA, USA
    schemaKey: Affiliation
  - name: Computational and Neural Systems Program, California Institute of Technology,
      Pasadena, CA, USA
    schemaKey: Affiliation
  - name: Center for Neural Science and Medicine, Department of Biomedical Science,
      Cedars-Sinai Medical Center, Los Angeles, CA, USA
    schemaKey: Affiliation
  awardNumber: ''
  email: Ueli.Rutishauser@cshs.org
  identifier: 0000-0002-9207-7069
  includeInCitation: true
  name: Rutishauser, Ueli
  roleName:
  - dcite:Author
  - dcite:Conceptualization
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  - dcite:Resources
  - dcite:Software
  - dcite:Supervision
  - dcite:Validation
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  schemaKey: Person
- awardNumber: R01MH110831
  contactPoint: []
  includeInCitation: false
  name: National Institute of Mental Health
  roleName:
  - dcite:Sponsor
  schemaKey: Organization
- affiliation: []
  identifier: 0000-0002-1137-8987
  includeInCitation: false
  name: Sullivan, Shannon
  roleName:
  - dcite:DataCollector
  - dcite:Validation
  schemaKey: Person
- awardNumber: U01NS117839, U01NS098961
  contactPoint: []
  includeInCitation: false
  name: National Insitute of Neurological Disorders and Stroke
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dateCreated: '2023-03-30T17:37:36.429935+00:00'
datePublished: '2024-01-23T18:06:57.538865+00:00'
description: "We present a dataset of 1809 single neurons recorded from the human
  medial temporal lobe (amygdala and hippocampus) and medial frontal lobe (anterior
  cingulate cortex, pre-supplementary motor area, ventral medial prefrontal cortex)
  across 41 sessions from 21 patients that underwent intracranial monitoring for epileptic
  activity. Subjects first performed a screening task (907 neurons), based on which
  we identified images for which highly selective cells were present in the medial
  temporal lobe. Subjects then performed a working memory task (902 neurons), in which
  they were sequentially presented with 1-3 images, and following a maintenance period,
  were asked if a probe was identical to one of the currently maintained images. This
  Neural data without borders (NWB) formatted dataset includes spike times, extracellular
  spike waveforms, stimuli presented, behavior, electrode locations, and subject demographics.
  As validation, we replicate previous findings on the existence of concept cells
  and their persistent activity during working memory maintenance. This dataset provides
  a substantial amount of rare human single neuron recordings together with behavior,
  thereby enabling investigation of the neural mechanisms of working memory at the
  single-neuron level.\n\nThis code accompanies the following data descriptor: \n*
  Kyzar M, Kami\u0144ski J, Brzezicka A, Reed CM, Chung JM, Mamelak AN, Rutishauser
  U. Dataset of human-single neuron activity during a Sternberg working memory task.
  Sci Data. 2024 Jan 18;11(1):89. doi: 10.1038/s41597-024-02943-8. PMID: 38238342;
  PMCID: PMC10796636.\n  [Link to Paper](https://pubmed.ncbi.nlm.nih.gov/38238342/)\n*
  Sample code to access and analyze this dataset has been provided: https://github.com/rutishauserlab/workingmem-release-NWB\n"
doi: 10.48324/dandi.000469/0.240123.1806
ethicsApproval: []
id: DANDI:000469/0.240123.1806
identifier: DANDI:000469
keywords:
- cognitive neuroscience
- data standardization
- working memory
- neurophysiology
- neurosurgery
- NWB
- open source
- single-neurons
license:
- spdx:CC-BY-4.0
manifestLocation:
- https://dandiarchive.s3.amazonaws.com/dandisets/000469/0.240123.1806/assets.yaml
name: Dataset of human-single neuron activity during a Sternberg working memory task.
protocol: []
publishedBy:
  endDate: '2024-01-23T18:06:57.538865+00:00'
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  name: DANDI publish
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  startDate: '2024-01-23T18:06:57.538865+00:00'
  wasAssociatedWith:
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    identifier: RRID:SCR_017571
    name: DANDI API
    schemaKey: Software
    version: 0.1.0
relatedResource:
- identifier: doi.org/10.1038/s41597-024-02943-8
  name: Dataset of human-single neuron activity during a Sternberg working memory
    task
  relation: dcite:IsSupplementTo
  repository: Scientific Data
  schemaKey: Resource
  url: https://www.nature.com/articles/s41597-024-02943-8
- identifier: https://doi.org/10.5281/zenodo.8161627
  name: 'Source code for: Dataset of human-single neuron activity during a Sternberg
    working memory task'
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  repository: workingmem-release-NWB
  schemaKey: Resource
  url: https://github.com/rutishauserlab/workingmem-release-NWB
- identifier: 10.1038/nn.4509
  name: Persistently active neurons in human medial frontal and medial temporal lobe
    support working memory
  relation: dcite:IsDerivedFrom
  repository: Nature Neuroscience
  schemaKey: Resource
  url: https://www.nature.com/articles/nn.4509
- identifier: 10.1016/j.neuron.2020.01.032
  name: Combined Phase-Rate Coding by Persistently Active Neurons as a Mechanism for
    Maintaining Multiple Items in Working Memory in Humans
  relation: dcite:IsDerivedFrom
  repository: Neuron
  schemaKey: Resource
  url: https://www.sciencedirect.com/science/article/pii/S0896627320300581?via%3Dihub
repository: https://dandiarchive.org
schemaKey: Dandiset
schemaVersion: 0.6.4
studyTarget: []
url: https://dandiarchive.org/dandiset/000469/0.240123.1806
version: 0.240123.1806
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