diff --git a/.github/workflows/build-depends.yml b/.github/workflows/build-depends.yml
index e942a59776f8a..5eafd46f9ca56 100644
--- a/.github/workflows/build-depends.yml
+++ b/.github/workflows/build-depends.yml
@@ -51,9 +51,18 @@ jobs:
             depends/sources
           key: depends-sources-${{ hashFiles('depends/packages/*') }}
           restore-keys: |
-            depends-sources-${{ hashFiles('depends/packages/*') }}
             depends-sources-
 
+      - name: Cache SDKs
+        uses: actions/cache@v4
+        if: inputs.build-target == 'mac'
+        with:
+          path: |
+            depends/SDKs
+          key: depends-sdks-${{ hashFiles('depends/hosts/darwin.mk') }}
+          restore-keys: |
+            depends-sdks-
+
       - name: Restore cached depends
         uses: actions/cache/restore@v4
         id: restore
@@ -61,13 +70,18 @@ jobs:
           path: |
             depends/built
             depends/${{ steps.setup.outputs.HOST }}
-          key: ${{ runner.os }}-depends-${{ inputs.build-target }}-${{ steps.setup.outputs.DEP_HASH }}-${{ hashFiles('depends/packages/*') }}
+          key: depends-${{ hashFiles('contrib/containers/ci/Dockerfile') }}-${{ inputs.build-target }}-${{ steps.setup.outputs.DEP_HASH }}-${{ hashFiles('depends/packages/*') }}
           restore-keys: |
-            ${{ runner.os }}-depends-${{ inputs.build-target }}-${{ hashFiles('depends/packages/*') }}
-            ${{ runner.os }}-depends-${{ inputs.build-target }}
+            depends-${{ hashFiles('contrib/containers/ci/Dockerfile') }}-${{ inputs.build-target }}-${{ steps.setup.outputs.DEP_HASH }}-
+            depends-${{ hashFiles('contrib/containers/ci/Dockerfile') }}-${{ inputs.build-target }}-
 
       - name: Build depends
-        run: env ${{ steps.setup.outputs.DEP_OPTS }} HOST=${{ steps.setup.outputs.HOST }} make -j$(nproc) -C depends
+        run: |
+          export HOST="${{ steps.setup.outputs.HOST  }}"
+          if [ "${HOST}" = "x86_64-apple-darwin" ]; then
+            ./contrib/containers/guix/scripts/setup-sdk
+          fi
+          env ${{ steps.setup.outputs.DEP_OPTS }} make -j$(nproc) -C depends
 
       - name: Save depends cache
         uses: actions/cache/save@v4
diff --git a/.github/workflows/build-src.yml b/.github/workflows/build-src.yml
index 45411eaa51f5c..88f91811f1188 100644
--- a/.github/workflows/build-src.yml
+++ b/.github/workflows/build-src.yml
@@ -44,6 +44,15 @@ jobs:
           echo "PR_BASE_SHA=${{ github.event.pull_request.base.sha || '' }}" >> $GITHUB_OUTPUT
         shell: bash
 
+      - name: Restore SDKs cache
+        uses: actions/cache/restore@v4
+        if: inputs.build-target == 'mac'
+        with:
+          path: |
+            depends/SDKs
+          key: depends-sdks-${{ hashFiles('depends/hosts/darwin.mk') }}
+          fail-on-cache-miss: true
+
       - name: Restore depends cache
         uses: actions/cache/restore@v4
         with:
@@ -58,11 +67,9 @@ jobs:
         with:
           path: |
             /cache
-          key: ${{ runner.os }}-${{ inputs.build-target }}-${{ github.sha }}
+          key: ccache-${{ hashFiles('contrib/containers/ci/Dockerfile', 'depends/packages/*') }}-${{ inputs.build-target }}-${{ github.sha }}
           restore-keys: |
-            ${{ runner.os }}-${{ inputs.build-target }}-${{ github.sha }}
-            ${{ runner.os }}-${{ inputs.build-target }}-${{ steps.setup.outputs.HOST }}
-            ${{ runner.os }}-${{ inputs.build-target }}
+            ccache-${{ hashFiles('contrib/containers/ci/Dockerfile', 'depends/packages/*') }}-${{ inputs.build-target }}-
 
       - name: Build source and run unit tests
         run: |
diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 424e47e43665e..6b14bf2dfa1ee 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -49,6 +49,14 @@ jobs:
       build-target: linux64_nowallet
       container-path: ${{ needs.container.outputs.path }}
 
+  depends-mac:
+    name: x86_64-apple-darwin
+    uses: ./.github/workflows/build-depends.yml
+    needs: [container]
+    with:
+      build-target: mac
+      container-path: ${{ needs.container.outputs.path }}
+
   depends-win64:
     name: x86_64-w64-mingw32
     uses: ./.github/workflows/build-depends.yml
@@ -129,6 +137,15 @@ jobs:
       container-path: ${{ needs.container.outputs.path }}
       depends-key: ${{ needs.depends-linux64.outputs.key }}
 
+  src-mac:
+    name: mac-build
+    uses: ./.github/workflows/build-src.yml
+    needs: [container, depends-mac]
+    with:
+      build-target: mac
+      container-path: ${{ needs.container.outputs.path }}
+      depends-key: ${{ needs.depends-mac.outputs.key }}
+
   src-win64:
     name: win64-build
     uses: ./.github/workflows/build-src.yml
diff --git a/contrib/guix/libexec/build.sh b/contrib/guix/libexec/build.sh
index ea1d5079ee3d7..b44eff598e22f 100755
--- a/contrib/guix/libexec/build.sh
+++ b/contrib/guix/libexec/build.sh
@@ -73,11 +73,9 @@ unset OBJCPLUS_INCLUDE_PATH
 
 export C_INCLUDE_PATH="${NATIVE_GCC}/include"
 export CPLUS_INCLUDE_PATH="${NATIVE_GCC}/include/c++:${NATIVE_GCC}/include"
-export OBJC_INCLUDE_PATH="${NATIVE_GCC}/include"
-export OBJCPLUS_INCLUDE_PATH="${NATIVE_GCC}/include/c++:${NATIVE_GCC}/include"
 
 case "$HOST" in
-    *darwin*) export LIBRARY_PATH="${NATIVE_GCC}/lib" ;;
+    *darwin*) export LIBRARY_PATH="${NATIVE_GCC}/lib" ;; # Required for qt/qmake
     *mingw*) export LIBRARY_PATH="${NATIVE_GCC}/lib" ;;
     *)
         NATIVE_GCC_STATIC="$(store_path gcc-toolchain static)"
@@ -182,6 +180,14 @@ make -C depends --jobs="$JOBS" HOST="$HOST" \
                                    x86_64_linux_NM=x86_64-linux-gnu-gcc-nm \
                                    x86_64_linux_STRIP=x86_64-linux-gnu-strip
 
+case "$HOST" in
+    *darwin*)
+        # Unset now that Qt is built
+        unset C_INCLUDE_PATH
+        unset CPLUS_INCLUDE_PATH
+        unset LIBRARY_PATH
+        ;;
+esac
 
 ###########################
 # Source Tarball Building #
diff --git a/depends/hosts/darwin.mk b/depends/hosts/darwin.mk
index 564381d1e9308..a50e36110dc02 100644
--- a/depends/hosts/darwin.mk
+++ b/depends/hosts/darwin.mk
@@ -50,17 +50,11 @@ darwin_STRIP=$(shell $(SHELL) $(.SHELLFLAGS) "command -v llvm-strip")
 #         Disable adhoc codesigning (for now) when using LLVM tooling, to avoid
 #         non-determinism issues with the Identifier field.
 
-darwin_CC=env -u C_INCLUDE_PATH -u CPLUS_INCLUDE_PATH \
-              -u OBJC_INCLUDE_PATH -u OBJCPLUS_INCLUDE_PATH -u CPATH \
-              -u LIBRARY_PATH \
-              $(clang_prog) --target=$(host) \
+darwin_CC=$(clang_prog) --target=$(host) \
               -isysroot$(OSX_SDK) -nostdlibinc \
               -iwithsysroot/usr/include -iframeworkwithsysroot/System/Library/Frameworks
 
-darwin_CXX=env -u C_INCLUDE_PATH -u CPLUS_INCLUDE_PATH \
-               -u OBJC_INCLUDE_PATH -u OBJCPLUS_INCLUDE_PATH -u CPATH \
-               -u LIBRARY_PATH \
-               $(clangxx_prog) --target=$(host) \
+darwin_CXX=$(clangxx_prog) --target=$(host) \
                -isysroot$(OSX_SDK) -nostdlibinc \
                -iwithsysroot/usr/include/c++/v1 \
                -iwithsysroot/usr/include -iframeworkwithsysroot/System/Library/Frameworks
diff --git a/depends/packages/qt.mk b/depends/packages/qt.mk
index 18c01e7cf0631..575a0e76f49e3 100644
--- a/depends/packages/qt.mk
+++ b/depends/packages/qt.mk
@@ -25,6 +25,7 @@ $(package)_patches += memory_resource.patch
 $(package)_patches += clang_18_libpng.patch
 $(package)_patches += utc_from_string_no_optimize.patch
 $(package)_patches += windows_lto.patch
+$(package)_patches += darwin_no_libm.patch
 $(package)_patches += zlib-timebits64.patch
 
 $(package)_qttranslations_file_name=qttranslations-$($(package)_suffix)
@@ -258,6 +259,7 @@ define $(package)_preprocess_cmds
   patch -p1 -i $($(package)_patch_dir)/fast_fixed_dtoa_no_optimize.patch && \
   patch -p1 -i $($(package)_patch_dir)/guix_cross_lib_path.patch && \
   patch -p1 -i $($(package)_patch_dir)/windows_lto.patch && \
+  patch -p1 -i $($(package)_patch_dir)/darwin_no_libm.patch && \
   patch -p1 -i $($(package)_patch_dir)/zlib-timebits64.patch && \
   mkdir -p qtbase/mkspecs/macx-clang-linux &&\
   cp -f qtbase/mkspecs/macx-clang/qplatformdefs.h qtbase/mkspecs/macx-clang-linux/ &&\
diff --git a/depends/patches/qt/darwin_no_libm.patch b/depends/patches/qt/darwin_no_libm.patch
new file mode 100644
index 0000000000000..38a94beeb7a69
--- /dev/null
+++ b/depends/patches/qt/darwin_no_libm.patch
@@ -0,0 +1,17 @@
+build: remove explicit -lm link from qttools
+    
+This causes issues with at least the macOS cross build, and shouldn't
+actually be required anywhere else. GCC with libstdc++ will already get libm.
+
+--- a/qtbase/src/corelib/tools/tools.pri
++++ b/qtbase/src/corelib/tools/tools.pri
+@@ -111,9 +111,6 @@ qtConfig(easingcurve) {
+         tools/qtimeline.cpp
+ }
+ 
+-# Note: libm should be present by default becaue this is C++
+-unix:!macx-icc:!vxworks:!haiku:!integrity:!wasm: LIBS_PRIVATE += -lm
+-
+ TR_EXCLUDE += ../3rdparty/*
+ 
+ # MIPS DSP