diff --git a/Cargo.lock b/Cargo.lock
index 2a21a541aed5b9..bd938b1a75803d 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -1108,6 +1108,7 @@ dependencies = [
  "digest 0.10.6",
  "ecb",
  "hex",
+ "hkdf",
  "idna 0.3.0",
  "indexmap",
  "libz-sys",
diff --git a/Cargo.toml b/Cargo.toml
index c12b14af1b1afa..2cdf4b375e5319 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -138,6 +138,7 @@ zstd = "=0.11.2"
 
 # crypto
 rsa = { version = "0.7.0", default-features = false, features = ["std", "pem", "hazmat"] } # hazmat needed for PrehashSigner in ext/node
+hkdf = "0.12.3"
 
 # macros
 proc-macro2 = "1"
diff --git a/cli/tests/node_compat/config.json b/cli/tests/node_compat/config.json
index e314c19581fd65..fc9a8d1318a8e3 100644
--- a/cli/tests/node_compat/config.json
+++ b/cli/tests/node_compat/config.json
@@ -228,6 +228,7 @@
       "test-console-sync-write-error.js",
       "test-console-table.js",
       "test-console-tty-colors.js",
+      "test-crypto-hkdf.js",
       "test-crypto-hmac.js",
       "test-crypto-prime.js",
       "test-crypto-secret-keygen.js",
diff --git a/cli/tests/node_compat/test/parallel/test-crypto-hkdf.js b/cli/tests/node_compat/test/parallel/test-crypto-hkdf.js
new file mode 100644
index 00000000000000..b5b35e3ce52d5d
--- /dev/null
+++ b/cli/tests/node_compat/test/parallel/test-crypto-hkdf.js
@@ -0,0 +1,203 @@
+// deno-fmt-ignore-file
+// deno-lint-ignore-file
+
+// Copyright Joyent and Node contributors. All rights reserved. MIT license.
+
+'use strict';
+
+const common = require('../common');
+
+if (!common.hasCrypto)
+  common.skip('missing crypto');
+
+const { kMaxLength } = require('buffer');
+const assert = require('assert');
+const {
+  createSecretKey,
+  hkdf,
+  hkdfSync
+} = require('crypto');
+
+{
+  assert.throws(() => hkdf(), {
+    code: 'ERR_INVALID_ARG_TYPE',
+    message: /The "digest" argument must be of type string/
+  });
+
+  [1, {}, [], false, Infinity].forEach((i) => {
+    assert.throws(() => hkdf(i, 'a'), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "digest" argument must be of type string/
+    });
+    assert.throws(() => hkdfSync(i, 'a'), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "digest" argument must be of type string/
+    });
+  });
+
+  [1, {}, [], false, Infinity].forEach((i) => {
+    assert.throws(() => hkdf('sha256', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "ikm" argument must be /
+    });
+    assert.throws(() => hkdfSync('sha256', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "ikm" argument must be /
+    });
+  });
+
+  [1, {}, [], false, Infinity].forEach((i) => {
+    assert.throws(() => hkdf('sha256', 'secret', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "salt" argument must be /
+    });
+    assert.throws(() => hkdfSync('sha256', 'secret', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "salt" argument must be /
+    });
+  });
+
+  [1, {}, [], false, Infinity].forEach((i) => {
+    assert.throws(() => hkdf('sha256', 'secret', 'salt', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "info" argument must be /
+    });
+    assert.throws(() => hkdfSync('sha256', 'secret', 'salt', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "info" argument must be /
+    });
+  });
+
+  ['test', {}, [], false].forEach((i) => {
+    assert.throws(() => hkdf('sha256', 'secret', 'salt', 'info', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "length" argument must be of type number/
+    });
+    assert.throws(() => hkdfSync('sha256', 'secret', 'salt', 'info', i), {
+      code: 'ERR_INVALID_ARG_TYPE',
+      message: /^The "length" argument must be of type number/
+    });
+  });
+
+  assert.throws(() => hkdf('sha256', 'secret', 'salt', 'info', -1), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+  assert.throws(() => hkdfSync('sha256', 'secret', 'salt', 'info', -1), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+  assert.throws(() => hkdf('sha256', 'secret', 'salt', 'info',
+                           kMaxLength + 1), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+  assert.throws(() => hkdfSync('sha256', 'secret', 'salt', 'info',
+                               kMaxLength + 1), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+
+  assert.throws(() => hkdfSync('unknown', 'a', '', '', 10), {
+    code: 'ERR_CRYPTO_INVALID_DIGEST'
+  });
+
+  assert.throws(() => hkdf('unknown', 'a', '', Buffer.alloc(1025), 10,
+                           common.mustNotCall()), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+
+  assert.throws(() => hkdfSync('unknown', 'a', '', Buffer.alloc(1025), 10), {
+    code: 'ERR_OUT_OF_RANGE'
+  });
+}
+
+const algorithms = [
+  ['sha256', 'secret', 'salt', 'info', 10],
+  ['sha256', '', '', '', 10],
+  ['sha256', '', 'salt', '', 10],
+  ['sha512', 'secret', 'salt', '', 15],
+];
+
+algorithms.forEach(([ hash, secret, salt, info, length ]) => {
+  {
+    const syncResult = hkdfSync(hash, secret, salt, info, length);
+    assert(syncResult instanceof ArrayBuffer);
+    let is_async = false;
+    hkdf(hash, secret, salt, info, length,
+         common.mustSucceed((asyncResult) => {
+           assert(is_async);
+           assert(asyncResult instanceof ArrayBuffer);
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+    // Keep this after the hkdf call above. This verifies
+    // that the callback is invoked asynchronously.
+    is_async = true;
+  }
+
+  {
+    const buf_secret = Buffer.from(secret);
+    const buf_salt = Buffer.from(salt);
+    const buf_info = Buffer.from(info);
+
+    const syncResult = hkdfSync(hash, buf_secret, buf_salt, buf_info, length);
+    hkdf(hash, buf_secret, buf_salt, buf_info, length,
+         common.mustSucceed((asyncResult) => {
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+  }
+
+  {
+    const key_secret = createSecretKey(Buffer.from(secret));
+    const buf_salt = Buffer.from(salt);
+    const buf_info = Buffer.from(info);
+
+    const syncResult = hkdfSync(hash, key_secret, buf_salt, buf_info, length);
+    hkdf(hash, key_secret, buf_salt, buf_info, length,
+         common.mustSucceed((asyncResult) => {
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+  }
+
+  {
+    const ta_secret = new Uint8Array(Buffer.from(secret));
+    const ta_salt = new Uint16Array(Buffer.from(salt));
+    const ta_info = new Uint32Array(Buffer.from(info));
+
+    const syncResult = hkdfSync(hash, ta_secret, ta_salt, ta_info, length);
+    hkdf(hash, ta_secret, ta_salt, ta_info, length,
+         common.mustSucceed((asyncResult) => {
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+  }
+
+  {
+    const ta_secret = new Uint8Array(Buffer.from(secret));
+    const ta_salt = new Uint16Array(Buffer.from(salt));
+    const ta_info = new Uint32Array(Buffer.from(info));
+
+    const syncResult = hkdfSync(
+      hash,
+      ta_secret.buffer,
+      ta_salt.buffer,
+      ta_info.buffer,
+      length);
+    hkdf(hash, ta_secret, ta_salt, ta_info, length,
+         common.mustSucceed((asyncResult) => {
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+  }
+
+  {
+    const ta_secret = new Uint8Array(Buffer.from(secret));
+    const sa_salt = new ArrayBuffer(0);
+    const sa_info = new ArrayBuffer(1);
+
+    const syncResult = hkdfSync(
+      hash,
+      ta_secret.buffer,
+      sa_salt,
+      sa_info,
+      length);
+    hkdf(hash, ta_secret, sa_salt, sa_info, length,
+         common.mustSucceed((asyncResult) => {
+           assert.deepStrictEqual(syncResult, asyncResult);
+         }));
+  }
+});
diff --git a/ext/node/Cargo.toml b/ext/node/Cargo.toml
index 4dbc79b9e19b99..e74cf380535352 100644
--- a/ext/node/Cargo.toml
+++ b/ext/node/Cargo.toml
@@ -20,6 +20,7 @@ deno_core.workspace = true
 digest = { version = "0.10.5", features = ["core-api", "std"] }
 ecb.workspace = true
 hex.workspace = true
+hkdf.workspace = true
 idna = "0.3.0"
 indexmap.workspace = true
 libz-sys = { version = "1.1.8", features = ["static"] }
diff --git a/ext/node/crypto/mod.rs b/ext/node/crypto/mod.rs
index 499e99fea8eec4..adacdf6d68e976 100644
--- a/ext/node/crypto/mod.rs
+++ b/ext/node/crypto/mod.rs
@@ -7,6 +7,7 @@ use deno_core::OpState;
 use deno_core::ResourceId;
 use deno_core::StringOrBuffer;
 use deno_core::ZeroCopyBuf;
+use hkdf::Hkdf;
 use num_bigint::BigInt;
 use rand::Rng;
 use std::future::Future;
@@ -419,3 +420,60 @@ pub async fn op_node_generate_secret_async(len: i32) -> ZeroCopyBuf {
   .await
   .unwrap()
 }
+
+fn hkdf_sync(
+  hash: &str,
+  ikm: &[u8],
+  salt: &[u8],
+  info: &[u8],
+  okm: &mut [u8],
+) -> Result<(), AnyError> {
+  macro_rules! hkdf {
+    ($hash:ty) => {{
+      let hk = Hkdf::<$hash>::new(Some(salt), ikm);
+      hk.expand(info, okm)
+        .map_err(|_| type_error("HKDF-Expand failed"))?;
+    }};
+  }
+
+  match hash {
+    "md4" => hkdf!(md4::Md4),
+    "md5" => hkdf!(md5::Md5),
+    "ripemd160" => hkdf!(ripemd::Ripemd160),
+    "sha1" => hkdf!(sha1::Sha1),
+    "sha224" => hkdf!(sha2::Sha224),
+    "sha256" => hkdf!(sha2::Sha256),
+    "sha384" => hkdf!(sha2::Sha384),
+    "sha512" => hkdf!(sha2::Sha512),
+    _ => return Err(type_error("Unknown digest")),
+  }
+
+  Ok(())
+}
+
+#[op]
+pub fn op_node_hkdf(
+  hash: &str,
+  ikm: &[u8],
+  salt: &[u8],
+  info: &[u8],
+  okm: &mut [u8],
+) -> Result<(), AnyError> {
+  hkdf_sync(hash, ikm, salt, info, okm)
+}
+
+#[op]
+pub async fn op_node_hkdf_async(
+  hash: String,
+  ikm: ZeroCopyBuf,
+  salt: ZeroCopyBuf,
+  info: ZeroCopyBuf,
+  okm_len: usize,
+) -> Result<ZeroCopyBuf, AnyError> {
+  tokio::task::spawn_blocking(move || {
+    let mut okm = vec![0u8; okm_len];
+    hkdf_sync(&hash, &ikm, &salt, &info, &mut okm)?;
+    Ok(okm.into())
+  })
+  .await?
+}
diff --git a/ext/node/lib.rs b/ext/node/lib.rs
index 478efaf27898ce..bf947f5e8dcf30 100644
--- a/ext/node/lib.rs
+++ b/ext/node/lib.rs
@@ -189,6 +189,8 @@ deno_core::extension!(deno_node,
     crypto::op_node_check_prime_bytes_async,
     crypto::op_node_pbkdf2,
     crypto::op_node_pbkdf2_async,
+    crypto::op_node_hkdf,
+    crypto::op_node_hkdf_async,
     crypto::op_node_generate_secret,
     crypto::op_node_generate_secret_async,
     crypto::op_node_sign,
diff --git a/ext/node/polyfills/internal/crypto/hkdf.ts b/ext/node/polyfills/internal/crypto/hkdf.ts
index deeba102f5f48f..fb26053df7ac22 100644
--- a/ext/node/polyfills/internal/crypto/hkdf.ts
+++ b/ext/node/polyfills/internal/crypto/hkdf.ts
@@ -7,6 +7,7 @@ import {
   validateString,
 } from "ext:deno_node/internal/validators.mjs";
 import {
+  ERR_CRYPTO_INVALID_DIGEST,
   ERR_INVALID_ARG_TYPE,
   ERR_OUT_OF_RANGE,
   hideStackFrames,
@@ -26,17 +27,19 @@ import {
   isAnyArrayBuffer,
   isArrayBufferView,
 } from "ext:deno_node/internal/util/types.ts";
-import { notImplemented } from "ext:deno_node/_utils.ts";
 
-const validateParameters = hideStackFrames((hash, key, salt, info, length) => {
-  key = prepareKey(key);
-  salt = toBuf(salt);
-  info = toBuf(info);
+const { core } = globalThis.__bootstrap;
+const { ops } = core;
 
+const validateParameters = hideStackFrames((hash, key, salt, info, length) => {
   validateString(hash, "digest");
+  key = new Uint8Array(prepareKey(key));
   validateByteSource(salt, "salt");
   validateByteSource(info, "info");
 
+  salt = new Uint8Array(toBuf(salt));
+  info = new Uint8Array(toBuf(info));
+
   validateInteger(length, "length", 0, kMaxLength);
 
   if (info.byteLength > 1024) {
@@ -91,7 +94,7 @@ export function hkdf(
   salt: BinaryLike,
   info: BinaryLike,
   length: number,
-  callback: (err: Error | null, derivedKey: ArrayBuffer) => void,
+  callback: (err: Error | null, derivedKey: ArrayBuffer | undefined) => void,
 ) {
   ({ hash, key, salt, info, length } = validateParameters(
     hash,
@@ -103,7 +106,9 @@ export function hkdf(
 
   validateFunction(callback, "callback");
 
-  notImplemented("crypto.hkdf");
+  core.opAsync("op_node_hkdf_async", hash, key, salt, info, length)
+    .then((okm) => callback(null, okm.buffer))
+    .catch((err) => callback(new ERR_CRYPTO_INVALID_DIGEST(err), undefined));
 }
 
 export function hkdfSync(
@@ -121,7 +126,14 @@ export function hkdfSync(
     length,
   ));
 
-  notImplemented("crypto.hkdfSync");
+  const okm = new Uint8Array(length);
+  try {
+    ops.op_node_hkdf(hash, key, salt, info, okm);
+  } catch (e) {
+    throw new ERR_CRYPTO_INVALID_DIGEST(e);
+  }
+
+  return okm.buffer;
 }
 
 export default {