diff --git a/src/Moq/Extensions.cs b/src/Moq/Extensions.cs
index 077fb67ec..5b53a0824 100644
--- a/src/Moq/Extensions.cs
+++ b/src/Moq/Extensions.cs
@@ -50,12 +50,12 @@ public static bool IsPropertyGetter(this MethodInfo method)
 
 		public static bool IsPropertyIndexerGetter(this MethodInfo method)
 		{
-			return method.IsSpecialName && method.Name.Equals("get_Item", StringComparison.Ordinal);
+			return method.IsSpecialName && method.Name.StartsWith("get_", StringComparison.Ordinal) && method.GetParameters().Length > 0;
 		}
 
 		public static bool IsPropertyIndexerSetter(this MethodInfo method)
 		{
-			return method.IsSpecialName && method.Name.Equals("set_Item", StringComparison.Ordinal);
+			return method.IsSpecialName && method.Name.StartsWith("set_", StringComparison.Ordinal) && method.GetParameters().Length > 1;
 		}
 
 		public static bool IsPropertySetter(this MethodInfo method)
diff --git a/tests/Moq.Tests/Regressions/IssueReportsFixture.cs b/tests/Moq.Tests/Regressions/IssueReportsFixture.cs
index 54c416db8..b136c8177 100644
--- a/tests/Moq.Tests/Regressions/IssueReportsFixture.cs
+++ b/tests/Moq.Tests/Regressions/IssueReportsFixture.cs
@@ -2705,10 +2705,24 @@ public void SetupAllProperties_can_process_Items_property_3()
 				Assert.NotNull(httpContext.Object.Items);
 			}
 
+			[Fact]
+			public void SetupAllProperties_can_process_Item_property()
+			{
+				var mock = new Mock<IFoo>();
+				mock.SetupAllProperties();
+				mock.Object.Item = "value";
+				Assert.Equal("value", mock.Object.Item);
+			}
+
 			public abstract partial class HttpContext
 			{
 				public abstract IDictionary<object, object> Items { get; set; }
 			}
+
+			public interface IFoo
+			{
+				string Item { get; set; }
+			}
 		}
 
 		#endregion