diff --git a/src/System.Security.Cryptography.X509Certificates/tests/X509FilesystemTests.Unix.cs b/src/System.Security.Cryptography.X509Certificates/tests/X509FilesystemTests.Unix.cs
index 070247a001de..0a9f7070524e 100644
--- a/src/System.Security.Cryptography.X509Certificates/tests/X509FilesystemTests.Unix.cs
+++ b/src/System.Security.Cryptography.X509Certificates/tests/X509FilesystemTests.Unix.cs
@@ -16,7 +16,7 @@ namespace System.Security.Cryptography.X509Certificates.Tests
     public static class X509FilesystemTests
     {
         // #9293: Our Fedora23 CI machines use NTFS for "tmphome", which causes our filesystem permissions checks to fail.
-        private static bool IsReliableInCI { get; } = !PlatformDetection.IsFedora23;
+        private static bool IsReliableInCI { get; } = !PlatformDetection.IsFedora23 && !PlatformDetection.IsUbuntu1610;
 
         [Fact]
         [OuterLoop]