diff --git a/src/libraries/System.Data.Common/src/ILLink/ILLink.Descriptors.LibraryBuild.xml b/src/libraries/System.Data.Common/src/ILLink/ILLink.Descriptors.LibraryBuild.xml
new file mode 100644
index 0000000000000..057b8b37f8367
--- /dev/null
+++ b/src/libraries/System.Data.Common/src/ILLink/ILLink.Descriptors.LibraryBuild.xml
@@ -0,0 +1,34 @@
+<?xml version="1.0" encoding="utf-8"?>
+<linker>
+  <assembly fullname="System.Data.Common">
+    <type fullname="System.Data.DataColumn">
+      <method name="ResetCaption" />
+      <method name="ResetNamespace" />
+      <method name="ShouldSerializeCaption" />
+      <method name="ShouldSerializeDefaultValue" />
+      <method name="ShouldSerializeNamespace" />
+    </type>
+    <type fullname="System.Data.DataRow">
+      <method name="ResetLastChangedColumn" />
+    </type>
+    <type fullname="System.Data.DataSet">
+      <method name="ResetRelations" />
+      <method name="ResetTables" />
+      <method name="ShouldSerializeLocale" />
+      <method name="ShouldSerializeRelations" />
+      <method name="ShouldSerializeTables" />
+    </type>
+    <type fullname="System.Data.DataTable">
+      <method name="ResetCaseSensitive" />
+      <method name="ResetColumns" />
+      <method name="ResetConstraints" />
+      <method name="ResetIndexes" />
+      <method name="ResetNamespace" />
+      <method name="ResetPrimaryKey" />
+      <method name="ShouldSerializeCaseSensitive" />
+      <method name="ShouldSerializeLocale" />
+      <method name="ShouldSerializeNamespace" />
+      <method name="ShouldSerializePrimaryKey" />
+    </type>
+  </assembly>
+</linker>
diff --git a/src/libraries/System.Data.Common/tests/System/Data/DataColumnTest.cs b/src/libraries/System.Data.Common/tests/System/Data/DataColumnTest.cs
index 8e318d2d13808..6f823a1561965 100644
--- a/src/libraries/System.Data.Common/tests/System/Data/DataColumnTest.cs
+++ b/src/libraries/System.Data.Common/tests/System/Data/DataColumnTest.cs
@@ -33,7 +33,7 @@
 
 using System.ComponentModel;
 using System.Data.SqlTypes;
-
+using System.Reflection;
 using Xunit;
 
 namespace System.Data.Tests
@@ -793,6 +793,54 @@ public void NonSqlNullableType_RequiresPublicStaticNull()
             Assert.Throws<ArgumentException>(() => t.Columns.Add("c3", typeof(NullableTypeWithoutNullMember)));
         }
 
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmed()
+        {
+            Assert.True(ShouldSerializeExists(nameof(DataColumn.Caption)));
+            Assert.True(ShouldSerializeExists(nameof(DataColumn.DefaultValue)));
+            Assert.True(ShouldSerializeExists(nameof(DataColumn.Namespace)));
+
+            Assert.True(ResetExists(nameof(DataColumn.Caption)));
+            Assert.False(ResetExists(nameof(DataColumn.DefaultValue)));
+            Assert.True(ResetExists(nameof(DataColumn.Namespace)));
+
+            bool ShouldSerializeExists(string name) => typeof(DataColumn).GetMethod("ShouldSerialize" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+            bool ResetExists(string name) => typeof(DataColumn).GetMethod("Reset" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+        }
+
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmedUsingTypeDescriptor()
+        {
+            DataColumn dc = new DataColumn
+            {
+                ColumnName = "dataColumn",
+                DataType = typeof(DateTime)
+            };
+
+            PropertyDescriptorCollection properties = TypeDescriptor.GetProperties(dc);
+
+            Assert.False(properties[nameof(DataColumn.DefaultValue)].ShouldSerializeValue(dc));
+            dc.DefaultValue = DateTime.MinValue;
+            Assert.True(properties[nameof(DataColumn.DefaultValue)].ShouldSerializeValue(dc));
+            properties[nameof(DataColumn.DefaultValue)].ResetValue(dc);
+            Assert.Equal(DateTime.MinValue, dc.DefaultValue);
+            Assert.True(properties[nameof(DataColumn.DefaultValue)].ShouldSerializeValue(dc));
+
+            Assert.False(properties[nameof(DataColumn.Caption)].ShouldSerializeValue(dc));
+            dc.Caption = "Caption";
+            Assert.True(properties[nameof(DataColumn.Caption)].ShouldSerializeValue(dc));
+            properties[nameof(DataColumn.Caption)].ResetValue(dc);
+            Assert.False(properties[nameof(DataColumn.Caption)].ShouldSerializeValue(dc));
+            Assert.Equal("dataColumn", dc.Caption);
+
+            Assert.False(properties[nameof(DataColumn.Namespace)].ShouldSerializeValue(dc));
+            dc.Namespace = "Namespace";
+            Assert.True(properties[nameof(DataColumn.Namespace)].ShouldSerializeValue(dc));
+            properties[nameof(DataColumn.Namespace)].ResetValue(dc);
+            Assert.False(properties[nameof(DataColumn.Namespace)].ShouldSerializeValue(dc));
+            Assert.Equal("", dc.Namespace);
+        }
+
         private sealed class NullableTypeWithNullProperty : INullable
         {
             public bool IsNull => true;
diff --git a/src/libraries/System.Data.Common/tests/System/Data/DataRowTest.cs b/src/libraries/System.Data.Common/tests/System/Data/DataRowTest.cs
index 5dd1ba770cc5f..07acb864750f2 100644
--- a/src/libraries/System.Data.Common/tests/System/Data/DataRowTest.cs
+++ b/src/libraries/System.Data.Common/tests/System/Data/DataRowTest.cs
@@ -29,7 +29,7 @@
 // WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
 //
 
-
+using System.Reflection;
 using Xunit;
 
 namespace System.Data.Tests
@@ -876,5 +876,15 @@ public void SetParent_missing_ParentRow()
             Assert.Equal(DBNull.Value, childRow[childColumn1]);
             Assert.Equal("value", childRow[childColumn2]);
         }
+
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmed()
+        {
+            Assert.False(ShouldSerializeExists("LastChangedColumn"));
+            Assert.True(ResetExists("LastChangedColumn"));
+
+            bool ShouldSerializeExists(string name) => typeof(DataRow).GetProperty("ShouldSerialize" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+            bool ResetExists(string name) => typeof(DataRow).GetMethod("Reset" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+        }
     }
 }
diff --git a/src/libraries/System.Data.Common/tests/System/Data/DataSetTest.cs b/src/libraries/System.Data.Common/tests/System/Data/DataSetTest.cs
index f8edbc0491e6f..0c9a4dc2a8fbc 100644
--- a/src/libraries/System.Data.Common/tests/System/Data/DataSetTest.cs
+++ b/src/libraries/System.Data.Common/tests/System/Data/DataSetTest.cs
@@ -41,6 +41,7 @@
 using Microsoft.DotNet.RemoteExecutor;
 using Xunit;
 using System.Tests;
+using System.Reflection;
 
 namespace System.Data.Tests
 {
@@ -1621,6 +1622,21 @@ static void RunTest()
             }
         }
 
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmed()
+        {
+            Assert.True(ShouldSerializeExists(nameof(DataSet.Relations)));
+            Assert.True(ShouldSerializeExists(nameof(DataSet.Tables)));
+            Assert.True(ShouldSerializeExists(nameof(DataSet.Locale)));
+
+            Assert.True(ResetExists(nameof(DataSet.Relations)));
+            Assert.True(ResetExists(nameof(DataSet.Tables)));
+            Assert.False(ResetExists(nameof(DataSet.Locale)));
+
+            bool ShouldSerializeExists(string name) => typeof(DataSet).GetMethod("ShouldSerialize" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+            bool ResetExists(string name) => typeof(DataSet).GetMethod("Reset" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+        }
+
         #region DataSet.CreateDataReader Tests and DataSet.Load Tests
 
         private DataSet _ds;
diff --git a/src/libraries/System.Data.Common/tests/System/Data/DataTableTest.cs b/src/libraries/System.Data.Common/tests/System/Data/DataTableTest.cs
index bc032b1208fc7..4fb880b51ea3c 100644
--- a/src/libraries/System.Data.Common/tests/System/Data/DataTableTest.cs
+++ b/src/libraries/System.Data.Common/tests/System/Data/DataTableTest.cs
@@ -33,6 +33,7 @@
 using System.Diagnostics;
 using System.Globalization;
 using System.IO;
+using System.Reflection;
 using System.Runtime.Serialization.Formatters.Binary;
 using System.Runtime.Serialization.Formatters.Tests;
 using System.Tests;
@@ -1818,6 +1819,60 @@ public void TableInitializedEventTest4()
             dt.Initialized -= new EventHandler(OnTableInitialized);
         }
 
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmed()
+        {
+            Assert.True(ShouldSerializeExists(nameof(DataTable.CaseSensitive)));
+            Assert.False(ShouldSerializeExists("Columns"));
+            Assert.False(ShouldSerializeExists("Constraints"));
+            Assert.False(ShouldSerializeExists("Indexes"));
+            Assert.True(ShouldSerializeExists(nameof(DataTable.Locale)));
+            Assert.True(ShouldSerializeExists(nameof(DataTable.Namespace)));
+            Assert.True(ShouldSerializeExists(nameof(DataTable.PrimaryKey)));
+
+            Assert.True(ResetExists(nameof(DataTable.CaseSensitive)));
+            Assert.True(ResetExists("Columns"));
+            Assert.True(ResetExists("Constraints"));
+            Assert.True(ResetExists("Indexes"));
+            Assert.False(ResetExists(nameof(DataTable.Locale)));
+            Assert.True(ResetExists(nameof(DataTable.Namespace)));
+            Assert.True(ResetExists(nameof(DataTable.PrimaryKey)));
+
+            bool ShouldSerializeExists(string name) => typeof(DataTable).GetMethod("ShouldSerialize" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+            bool ResetExists(string name) => typeof(DataTable).GetMethod("Reset" + name, BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.Public) != null;
+        }
+
+        [Fact]
+        public void MethodsCalledByReflectionSerializersAreNotTrimmedUsingTypeDescriptor()
+        {
+            DataTable dt = new DataTable();
+            dt.CaseSensitive = true;
+            dt.Locale = new CultureInfo("en-US");
+            dt.PrimaryKey = new DataColumn[] { dt.Columns.Add("id", typeof(int)) };
+            dt.Namespace = "NS";
+
+            PropertyDescriptorCollection properties = TypeDescriptor.GetProperties(dt);
+
+            Assert.True(properties[nameof(DataTable.PrimaryKey)].ShouldSerializeValue(dt));
+            properties[nameof(DataTable.PrimaryKey)].ResetValue(dt);
+            Assert.False(properties[nameof(DataTable.PrimaryKey)].ShouldSerializeValue(dt));
+            Assert.Equal(0, dt.PrimaryKey.Length);
+
+            Assert.True(properties[nameof(DataTable.CaseSensitive)].ShouldSerializeValue(dt));
+            properties[nameof(DataTable.CaseSensitive)].ResetValue(dt);
+            Assert.False(properties[nameof(DataTable.CaseSensitive)].ShouldSerializeValue(dt));
+            Assert.False(dt.CaseSensitive);
+
+            Assert.True(properties[nameof(DataTable.Locale)].ShouldSerializeValue(dt));
+            properties[nameof(DataTable.Locale)].ResetValue(dt);
+            Assert.True(properties[nameof(DataTable.Locale)].ShouldSerializeValue(dt)); // Reset method is not available
+
+            Assert.True(properties[nameof(DataTable.Namespace)].ShouldSerializeValue(dt));
+            properties[nameof(DataTable.Namespace)].ResetValue(dt);
+            Assert.False(properties[nameof(DataTable.Namespace)].ShouldSerializeValue(dt));
+            Assert.Equal("", dt.Namespace);
+        }
+
         private void OnTableInitialized(object src, EventArgs args)
         {
             _tableInitialized = true;