diff --git a/src/libraries/System.Net.Http/src/System/Net/Http/SocketsHttpHandler/Http3RequestStream.cs b/src/libraries/System.Net.Http/src/System/Net/Http/SocketsHttpHandler/Http3RequestStream.cs
index ef2532b2b22d0..d036e955c3047 100644
--- a/src/libraries/System.Net.Http/src/System/Net/Http/SocketsHttpHandler/Http3RequestStream.cs
+++ b/src/libraries/System.Net.Http/src/System/Net/Http/SocketsHttpHandler/Http3RequestStream.cs
@@ -275,6 +275,12 @@ await Task.WhenAny(sendRequestTask, readResponseTask).ConfigureAwait(false) == s
                 Exception abortException = _connection.Abort(HttpProtocolException.CreateHttp3ConnectionException(code, SR.net_http_http3_connection_close));
                 throw new HttpRequestException(HttpRequestError.HttpProtocolError, SR.net_http_client_execution_error, abortException);
             }
+            catch (QuicException ex) when (ex.QuicError == QuicError.OperationAborted && cancellationToken.IsCancellationRequested)
+            {
+                // It is possible for QuicStream's code to throw an
+                // OperationAborted QuicException when cancellation is requested.
+                throw new TaskCanceledException(ex.Message, ex, cancellationToken);
+            }
             catch (QuicException ex) when (ex.QuicError == QuicError.OperationAborted && _connection.AbortException != null)
             {
                 // we closed the connection already, propagate the AbortException
@@ -1277,6 +1283,11 @@ private void HandleReadResponseContentException(Exception ex, CancellationToken
                         : HttpRequestError.Unknown;
                     throw new HttpRequestException(httpRequestError, SR.net_http_client_execution_error, _connection.AbortException);
 
+                case QuicException e when (e.QuicError == QuicError.OperationAborted && cancellationToken.IsCancellationRequested):
+                    // It is possible for QuicStream's code to throw an
+                    // OperationAborted QuicException when cancellation is requested.
+                    throw new TaskCanceledException(e.Message, e, cancellationToken);
+
                 case HttpIOException:
                     _connection.Abort(ex);
                     ExceptionDispatchInfo.Throw(ex); // Rethrow.