diff --git a/easybuild/easyblocks/o/ocaml.py b/easybuild/easyblocks/o/ocaml.py
index 0a8d9c8172..3da2cdda44 100644
--- a/easybuild/easyblocks/o/ocaml.py
+++ b/easybuild/easyblocks/o/ocaml.py
@@ -86,7 +86,8 @@ def __init__(self, *args, **kwargs):
     def configure_step(self):
         """Custom configuration procedure for OCaml."""
         self.cfg['prefix_opt'] = '-prefix '
-        self.cfg.update('configopts', '-cc "%s %s"' % (os.environ['CC'], os.environ['CFLAGS']))
+        if LooseVersion(self.version) < LooseVersion("4.12"):
+            self.cfg.update('configopts', '-cc "%s %s"' % (os.environ['CC'], os.environ['CFLAGS']))
 
         if 'world.opt' not in self.cfg['buildopts']:
             self.cfg.update('buildopts', 'world.opt')