diff --git a/x-pack/plugins/actions/README.md b/x-pack/plugins/actions/README.md
index 9472cbf400a6a..04cdc477266e9 100644
--- a/x-pack/plugins/actions/README.md
+++ b/x-pack/plugins/actions/README.md
@@ -639,7 +639,7 @@ The following table describes the properties of the `incident` object.
 | externalId  | The id of the issue in Jira. If presented the incident will be update. Otherwise a new incident will be created. | string _(optional)_   |
 | issueType   | The id of the issue type in Jira.                                                                                | string _(optional)_   |
 | priority    | The name of the priority in Jira. Example: `Medium`.                                                             | string _(optional)_   |
-| labels      | An array of labels.                                                                                              | string[] _(optional)_ |
+| labels      | An array of labels. Labels cannot contain spaces.                                                                | string[] _(optional)_ |
 | parent      | The parent issue id or key. Only for `Sub-task` issue types.                                                     | string _(optional)_   |
 
 #### `subActionParams (getIncident)`
diff --git a/x-pack/plugins/actions/server/builtin_action_types/jira/schema.ts b/x-pack/plugins/actions/server/builtin_action_types/jira/schema.ts
index 552053bdd7651..a81dfaeef8175 100644
--- a/x-pack/plugins/actions/server/builtin_action_types/jira/schema.ts
+++ b/x-pack/plugins/actions/server/builtin_action_types/jira/schema.ts
@@ -40,7 +40,15 @@ export const ExecutorSubActionPushParamsSchema = schema.object({
     externalId: schema.nullable(schema.string()),
     issueType: schema.nullable(schema.string()),
     priority: schema.nullable(schema.string()),
-    labels: schema.nullable(schema.arrayOf(schema.string())),
+    labels: schema.nullable(
+      schema.arrayOf(
+        schema.string({
+          validate: (label) =>
+            // Matches any space, tab or newline character.
+            label.match(/\s/g) ? `The label ${label} cannot contain spaces` : undefined,
+        })
+      )
+    ),
     parent: schema.nullable(schema.string()),
   }),
   comments: schema.nullable(
diff --git a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.test.tsx b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.test.tsx
index 39885b2880c1f..cf9ba31b2bba1 100644
--- a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.test.tsx
+++ b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.test.tsx
@@ -84,7 +84,7 @@ describe('jira action params validation', () => {
     };
 
     expect(actionTypeModel.validateParams(actionParams)).toEqual({
-      errors: { summary: [] },
+      errors: { summary: [], labels: [] },
     });
   });
 
@@ -96,6 +96,23 @@ describe('jira action params validation', () => {
     expect(actionTypeModel.validateParams(actionParams)).toEqual({
       errors: {
         summary: ['Summary is required.'],
+        labels: [],
+      },
+    });
+  });
+
+  test('params validation fails when labels contain spaces', () => {
+    const actionParams = {
+      subActionParams: {
+        incident: { summary: 'some title', labels: ['label with spaces'] },
+        comments: [],
+      },
+    };
+
+    expect(actionTypeModel.validateParams(actionParams)).toEqual({
+      errors: {
+        summary: [],
+        labels: ['Labels cannot contain spaces.'],
       },
     });
   });
diff --git a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.tsx b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.tsx
index 66b002661e266..c63895b108700 100644
--- a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.tsx
+++ b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira.tsx
@@ -63,6 +63,7 @@ export function getActionType(): ActionTypeModel<JiraConfig, JiraSecrets, JiraAc
       const validationResult = { errors: {} };
       const errors = {
         summary: new Array<string>(),
+        labels: new Array<string>(),
       };
       validationResult.errors = errors;
       if (
@@ -72,6 +73,12 @@ export function getActionType(): ActionTypeModel<JiraConfig, JiraSecrets, JiraAc
       ) {
         errors.summary.push(i18n.SUMMARY_REQUIRED);
       }
+
+      if (actionParams.subActionParams?.incident?.labels?.length) {
+        // Jira do not allows empty spaces on labels. If the label includes a whitespace show an error.
+        if (actionParams.subActionParams.incident.labels.some((label) => label.match(/\s/g)))
+          errors.labels.push(i18n.LABELS_WHITE_SPACES);
+      }
       return validationResult;
     },
     actionParamsFields: lazy(() => import('./jira_params')),
diff --git a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira_params.tsx b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira_params.tsx
index 0e61129f9f5b2..77068d2d69ade 100644
--- a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira_params.tsx
+++ b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/jira_params.tsx
@@ -184,6 +184,9 @@ const JiraParamsFields: React.FunctionComponent<ActionParamsProps<JiraActionPara
     // eslint-disable-next-line react-hooks/exhaustive-deps
   }, [actionParams]);
 
+  const areLabelsInvalid =
+    errors.labels != null && errors.labels.length > 0 && incident.labels !== undefined;
+
   return (
     <Fragment>
       <>
@@ -301,6 +304,8 @@ const JiraParamsFields: React.FunctionComponent<ActionParamsProps<JiraActionPara
                         defaultMessage: 'Labels',
                       }
                     )}
+                    error={errors.labels as string[]}
+                    isInvalid={areLabelsInvalid}
                   >
                     <EuiComboBox
                       noSuggestions
@@ -328,6 +333,7 @@ const JiraParamsFields: React.FunctionComponent<ActionParamsProps<JiraActionPara
                       }}
                       isClearable={true}
                       data-test-subj="labelsComboBox"
+                      isInvalid={areLabelsInvalid}
                     />
                   </EuiFormRow>
                 </EuiFlexItem>
diff --git a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/translations.ts b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/translations.ts
index 3c8bda7792f0a..fe7ea61e68193 100644
--- a/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/translations.ts
+++ b/x-pack/plugins/triggers_actions_ui/public/application/components/builtin_action_types/jira/translations.ts
@@ -199,3 +199,10 @@ export const SEARCH_ISSUES_LOADING = i18n.translate(
     defaultMessage: 'Loading...',
   }
 );
+
+export const LABELS_WHITE_SPACES = i18n.translate(
+  'xpack.triggersActionsUI.components.builtinActionTypes.jira.labelsSpacesErrorMessage',
+  {
+    defaultMessage: 'Labels cannot contain spaces.',
+  }
+);
diff --git a/x-pack/test/alerting_api_integration/security_and_spaces/tests/actions/builtin_action_types/jira.ts b/x-pack/test/alerting_api_integration/security_and_spaces/tests/actions/builtin_action_types/jira.ts
index 6cc5e2eaefb94..8bd0b8a790d40 100644
--- a/x-pack/test/alerting_api_integration/security_and_spaces/tests/actions/builtin_action_types/jira.ts
+++ b/x-pack/test/alerting_api_integration/security_and_spaces/tests/actions/builtin_action_types/jira.ts
@@ -375,6 +375,34 @@ export default function jiraTest({ getService }: FtrProviderContext) {
               });
             });
         });
+
+        it('should handle failing with a simulated success when labels containing a space', async () => {
+          await supertest
+            .post(`/api/actions/action/${simulatedActionId}/_execute`)
+            .set('kbn-xsrf', 'foo')
+            .send({
+              params: {
+                ...mockJira.params,
+                subActionParams: {
+                  incident: {
+                    ...mockJira.params.subActionParams.incident,
+                    issueType: '10006',
+                    labels: ['label with spaces'],
+                  },
+                  comments: [],
+                },
+              },
+            })
+            .then((resp: any) => {
+              expect(resp.body).to.eql({
+                actionId: simulatedActionId,
+                status: 'error',
+                retry: false,
+                message:
+                  'error validating action params: types that failed validation:\n- [0.subAction]: expected value to equal [getFields]\n- [1.subAction]: expected value to equal [getIncident]\n- [2.subAction]: expected value to equal [handshake]\n- [3.subActionParams.incident.labels]: types that failed validation:\n - [subActionParams.incident.labels.0.0]: The label label with spaces cannot contain spaces\n - [subActionParams.incident.labels.1]: expected value to equal [null]\n- [4.subAction]: expected value to equal [issueTypes]\n- [5.subAction]: expected value to equal [fieldsByIssueType]\n- [6.subAction]: expected value to equal [issues]\n- [7.subAction]: expected value to equal [issue]',
+              });
+            });
+        });
       });
 
       describe('Execution', () => {