diff --git a/src/jsifier.js b/src/jsifier.js
index fe02502e20d7..50a8256cc33a 100644
--- a/src/jsifier.js
+++ b/src/jsifier.js
@@ -98,7 +98,8 @@ function getTransitiveDeps(symbol) {
 }
 
 function shouldPreprocess(fileName) {
-  return read(fileName).trim().startsWith('#preprocess\n');
+  var content = read(fileName).trim()
+  return content.startsWith('#preprocess\n') || content.startsWith('#preprocess\r\n');
 }
 
 function preJS() {
diff --git a/test/test_other.py b/test/test_other.py
index 8b1387159e00..acc284d42c1b 100644
--- a/test/test_other.py
+++ b/test/test_other.py
@@ -14472,6 +14472,7 @@ def test_wasm64_no_asan(self):
     err = self.expect_fail([EMCC, test_file('hello_world.c'), '-sMEMORY64', '-fsanitize=address'])
     self.assertContained('error: MEMORY64 does not yet work with ASAN', err)
 
+  @crossplatform
   def test_js_preprocess_pre_post(self):
     create_file('pre.js', '''
     #preprocess