diff --git a/emcc.py b/emcc.py
index e091e4dd34402..b2577127df01b 100755
--- a/emcc.py
+++ b/emcc.py
@@ -2438,6 +2438,8 @@ def generate_html(target, options, js_target, target_basename,
             } else if (Module['memoryInitializerPrefixURL']) {
               memoryInitializer = Module['memoryInitializerPrefixURL'] + memoryInitializer;
             }
+            // If URL to memory initializer is relative, treat it relative with respect to Module['scriptDirectory'], if that is present.
+            if (Module['scriptDirectory'] && !/^(?:[a-z]+:)?\/\//i.test(memoryInitializer)) memoryInitializer = Module['scriptDirectory'] + memoryInitializer;
             var meminitXHR = Module['memoryInitializerRequest'] = new XMLHttpRequest();
             meminitXHR.open('GET', memoryInitializer, true);
             meminitXHR.responseType = 'arraybuffer';
diff --git a/src/Fetch.js b/src/Fetch.js
index e7b8477c704cf..f092f909e8049 100644
--- a/src/Fetch.js
+++ b/src/Fetch.js
@@ -115,6 +115,7 @@ var Fetch = {
       // of these are passed, then the default URL 'pthread-main.js' relative to the main html file is loaded.
       if (typeof Module['locateFile'] === 'function') fetchJs = Module['locateFile'](fetchJs);
       else if (Module['pthreadMainPrefixURL']) fetchJs = Module['pthreadMainPrefixURL'] + fetchJs;
+      fetchJs = joinUrl(Module['scriptDirectory'], fetchJs);
       Fetch.worker = new Worker(fetchJs);
       Fetch.worker.onmessage = function(e) {
         Module['print']('fetch-worker sent a message: ' + e.filename + ':' + e.lineno + ': ' + e.message);
diff --git a/src/library_debugger_toolkit.js b/src/library_debugger_toolkit.js
index 29cb532aecaaf..f70d3caf73aea 100644
--- a/src/library_debugger_toolkit.js
+++ b/src/library_debugger_toolkit.js
@@ -451,6 +451,7 @@ var CyberDWARFHeapPrinter = function(cdFileLocation) {
     } else if (Module['cdInitializerPrefixURL']) {
       cdFileLocation = Module['cdInitializerPrefixURL'] + cdFileLocation;
     }
+    cdFileLocation = joinUrl(Module['scriptDirectory'], cdFileLocation);
     if (ENVIRONMENT_IS_NODE || ENVIRONMENT_IS_SHELL) {
       var data = Module['read'](cdFileLocation);
       install_cyberdwarf(data);
diff --git a/src/library_pthread.js b/src/library_pthread.js
index f438799b7a367..c0c81210b4c4d 100644
--- a/src/library_pthread.js
+++ b/src/library_pthread.js
@@ -259,6 +259,7 @@ var LibraryPThread = {
         // of these are passed, then the default URL 'pthread-main.js' relative to the main html file is loaded.
         if (typeof Module['locateFile'] === 'function') pthreadMainJs = Module['locateFile'](pthreadMainJs);
         else if (Module['pthreadMainPrefixURL']) pthreadMainJs = Module['pthreadMainPrefixURL'] + pthreadMainJs;
+        pthreadMainJs = joinUrl(Module['scriptDirectory'], pthreadMainJs);
         var worker = new Worker(pthreadMainJs);
 
         worker.onmessage = function(e) {
diff --git a/src/postamble.js b/src/postamble.js
index 929d294c97bb2..8fd4c760ba6a3 100644
--- a/src/postamble.js
+++ b/src/postamble.js
@@ -44,6 +44,8 @@ if (memoryInitializer) {
   } else if (Module['memoryInitializerPrefixURL']) {
     memoryInitializer = Module['memoryInitializerPrefixURL'] + memoryInitializer;
   }
+  memoryInitializer = joinUrl(Module['scriptDirectory'], memoryInitializer);
+
   if (ENVIRONMENT_IS_NODE || ENVIRONMENT_IS_SHELL) {
     var data = Module['readBinary'](memoryInitializer);
     HEAPU8.set(data, Runtime.GLOBAL_BASE);
diff --git a/src/preamble.js b/src/preamble.js
index 70145dc0f9b4a..77a82c80cfde7 100644
--- a/src/preamble.js
+++ b/src/preamble.js
@@ -932,6 +932,16 @@ function stackTrace() {
 }
 {{{ maybeExport('stackTrace') }}}
 
+function isAbsoluteUrl(url) {
+  return /^(?:[a-z]+:)?\/\//i.test(url);
+}
+
+function joinUrl(a, b) {
+#if ASSERTIONS
+  if (a && !a.endsWith('/')) throw 'First parameter to joinUrl() should end in /'!;
+#endif
+  return a && !isAbsoluteUrl(b) ? a + b : b;
+}
 // Memory management
 
 var PAGE_SIZE = 16384;
@@ -2114,6 +2124,9 @@ function integrateWasmJS(Module) {
     wasmBinaryFile = Module['locateFile'](wasmBinaryFile);
     asmjsCodeFile = Module['locateFile'](asmjsCodeFile);
   }
+  wasmTextFile = joinUrl(Module['scriptDirectory'], wasmTextFile);
+  wasmBinaryFile = joinUrl(Module['scriptDirectory'], wasmBinaryFile);
+  asmjsCodeFile = joinUrl(Module['scriptDirectory'], asmjsCodeFile);
 
   // utilities
 
diff --git a/src/shell.js b/src/shell.js
index 789de77778b9f..fd3867ed2e61c 100644
--- a/src/shell.js
+++ b/src/shell.js
@@ -76,6 +76,7 @@ if (ENVIRONMENT_IS_NODE) {
   // Note that we pollute the global namespace here, otherwise we break in node
   if (!Module['print']) Module['print'] = console.log;
   if (!Module['printErr']) Module['printErr'] = console.warn;
+  if (!Module['scriptDirectory']) Module['scriptDirectory'] = __dirname + '/';
 
   var nodeFS;
   var nodePath;
diff --git a/tools/file_packager.py b/tools/file_packager.py
index 26e2ae92faab6..521f3c64b9aa5 100644
--- a/tools/file_packager.py
+++ b/tools/file_packager.py
@@ -833,6 +833,7 @@ def was_seen(name):
  var REMOTE_METADATA_NAME = typeof Module['locateFile'] === 'function' ?
                             Module['locateFile']('%(metadata_file)s') :
                             ((Module['filePackagePrefixURL'] || '') + '%(metadata_file)s');
+ REMOTE_METADATA_NAME = joinUrl(Module['scriptDirectory'], REMOTE_METADATA_NAME);
  var xhr = new XMLHttpRequest();
  xhr.onreadystatechange = function() {
   if (xhr.readyState === 4 && xhr.status === 200) {