diff --git a/Libraries/Animated/src/AnimatedImplementation.js b/Libraries/Animated/src/AnimatedImplementation.js
index 91b7bb3b5b7696..eb04cc8fbd5432 100644
--- a/Libraries/Animated/src/AnimatedImplementation.js
+++ b/Libraries/Animated/src/AnimatedImplementation.js
@@ -652,7 +652,7 @@ class AnimatedValue extends AnimatedWithChildren {
       this._animation.stop();
       this._animation = null;
     }
-    this._updateValue(value);
+    this._updateValue(value, !this.__isNative /* don't perform a flush for natively driven values */);
     if (this.__isNative) {
       NativeAnimatedAPI.setAnimatedNodeValue(this.__getNativeTag(), value);
     }
@@ -730,7 +730,9 @@ class AnimatedValue extends AnimatedWithChildren {
     animation.start(
       this._value,
       (value) => {
-        this._updateValue(value);
+        // Natively driven animations will never call into that callback, therefore we can always pass `flush = true`
+        // to allow the updated value to propagate to native with `setNativeProps`
+        this._updateValue(value, true /* flush */);
       },
       (result) => {
         this._animation = null;
@@ -760,9 +762,11 @@ class AnimatedValue extends AnimatedWithChildren {
     this._tracking = tracking;
   }
 
-  _updateValue(value: number): void {
+  _updateValue(value: number, flush: bool): void {
     this._value = value;
-    _flush(this);
+    if (flush) {
+      _flush(this);
+    }
     for (var key in this._listeners) {
       this._listeners[key]({value: this.__getValue()});
     }
diff --git a/Libraries/Animated/src/__tests__/AnimatedNative-test.js b/Libraries/Animated/src/__tests__/AnimatedNative-test.js
index 9fff20cb2792e2..166d836d306c16 100644
--- a/Libraries/Animated/src/__tests__/AnimatedNative-test.js
+++ b/Libraries/Animated/src/__tests__/AnimatedNative-test.js
@@ -210,10 +210,27 @@ describe('Animated', () => {
     var anim = new Animated.Value(0);
     Animated.timing(anim, {toValue: 10, duration: 1000, useNativeDriver: true}).start();
 
-    anim.setValue(5);
+    var c = new Animated.View();
+    c.props = {
+      style: {
+        opacity: anim,
+      },
+    };
+    c.componentWillMount();
+
+    // We expect `setValue` not to propagate down to `setNativeProps`, otherwise it may try to access `setNativeProps`
+    // via component refs table that we override here.
+    c.refs = {
+      node: {
+        setNativeProps: jest.genMockFunction(),
+      },
+    };
+
+    anim.setValue(0.5);
 
     var nativeAnimatedModule = require('NativeModules').NativeAnimatedModule;
-    expect(nativeAnimatedModule.setAnimatedNodeValue).toBeCalledWith(jasmine.any(Number), 5);
+    expect(nativeAnimatedModule.setAnimatedNodeValue).toBeCalledWith(jasmine.any(Number), 0.5);
+    expect(c.refs.node.setNativeProps.mock.calls.length).toBe(0);
   });
 
   it('doesn\'t call into native API if useNativeDriver is set to false', () => {