diff --git a/scripts/cocoapods/__tests__/utils-test.rb b/scripts/cocoapods/__tests__/utils-test.rb
index 5fac9c1ed4dcca..2a135b46c8d5e5 100644
--- a/scripts/cocoapods/__tests__/utils-test.rb
+++ b/scripts/cocoapods/__tests__/utils-test.rb
@@ -677,6 +677,74 @@ def test_applyFlagsForFabric_whenFabricDisabled_doNothing
             assert_nil(config.build_settings["OTHER_CFLAGS"])
         end
     end
+
+    # ============================= #
+    # Test - Enable Hermes Profiler #
+    # ============================= #
+
+    def test_enableHermesProfiler_whenEnableHermesProfileIsTrue_setsFlagsInRelease
+        # Arrange
+        first_target = prepare_target("FirstTarget")
+        second_target = prepare_target("SecondTarget")
+        third_target = prepare_target("ThirdTarget", "com.apple.product-type.bundle")
+        user_project_mock = UserProjectMock.new("a/path", [
+                prepare_config("Debug"),
+                prepare_config("Release"),
+            ],
+            :native_targets => [
+                first_target,
+                second_target
+            ]
+        )
+        pods_projects_mock = PodsProjectMock.new([third_target], {"hermes-engine" => {}})
+        installer = InstallerMock.new(pods_projects_mock, [
+            AggregatedProjectMock.new(user_project_mock)
+        ])
+
+         # Act
+         ReactNativePodsUtils.enable_hermes_profiler(installer, enable_hermes_profiler: true)
+
+         # Assert
+         installer.target_installation_results.pod_target_installation_results.each do |pod_name, target_installation_result|
+            target_installation_result.native_target.build_configurations.each do |config|
+                if config.name != "Release"
+                    assert_nil(config.build_settings["OTHER_CFLAGS"])
+                else
+                    assert_equal(config.build_settings["OTHER_CFLAGS"], "$(inherited) -DRCT_REMOTE_PROFILE=1")
+                end
+            end
+         end
+    end
+
+    def test_enableHermesProfiler_whenEnableHermesProfileIsFalse_doesNothing
+        # Arrange
+        first_target = prepare_target("FirstTarget")
+        second_target = prepare_target("SecondTarget")
+        third_target = prepare_target("ThirdTarget", "com.apple.product-type.bundle")
+        user_project_mock = UserProjectMock.new("a/path", [
+                prepare_config("Debug"),
+                prepare_config("Release"),
+            ],
+            :native_targets => [
+                first_target,
+                second_target
+            ]
+        )
+        pods_projects_mock = PodsProjectMock.new([third_target], {"hermes-engine" => {}})
+        installer = InstallerMock.new(pods_projects_mock, [
+            AggregatedProjectMock.new(user_project_mock)
+        ])
+
+         # Act
+         ReactNativePodsUtils.enable_hermes_profiler(installer)
+
+         # Assert
+         installer.target_installation_results.pod_target_installation_results.each do |pod_name, target_installation_result|
+            target_installation_result.native_target.build_configurations.each do |config|
+                assert_nil(config.build_settings["OTHER_CFLAGS"])
+            end
+         end
+    end
 end
 
 # ===== #
diff --git a/scripts/cocoapods/new_architecture.rb b/scripts/cocoapods/new_architecture.rb
index 207c79c2eb5a5b..a0606c59c557cd 100644
--- a/scripts/cocoapods/new_architecture.rb
+++ b/scripts/cocoapods/new_architecture.rb
@@ -50,7 +50,8 @@ def self.modify_flags_for_new_architecture(installer, is_new_arch_enabled)
 
                 if config_name == "Release"
                     config_file.attributes['OTHER_CPLUSPLUSFLAGS'] = config_file.attributes['OTHER_CPLUSPLUSFLAGS'] + ndebug_flag
-                    config_file.attributes['OTHER_CFLAGS'] = "$(inherited)" + ndebug_flag
+                    other_cflags = config_file.attributes['OTHER_CFLAGS'] != nil ? config_file.attributes['OTHER_CFLAGS'] : "$(inherited)"
+                    config_file.attributes['OTHER_CFLAGS'] = other_cflags + ndebug_flag
                 end
 
                 xcconfig_path = aggregate_target.xcconfig_path(config_name)
@@ -68,9 +69,10 @@ def self.modify_flags_for_new_architecture(installer, is_new_arch_enabled)
 
             target_installation_result.native_target.build_configurations.each do |config|
                 if config.name == "Release"
-                    current_flags = config.build_settings['OTHER_CPLUSPLUSFLAGS'] != nil ? config.build_settings['OTHER_CPLUSPLUSFLAGS'] : ""
+                    current_flags = config.build_settings['OTHER_CPLUSPLUSFLAGS'] != nil ? config.build_settings['OTHER_CPLUSPLUSFLAGS'] : "$(inherited)"
                     config.build_settings['OTHER_CPLUSPLUSFLAGS'] = current_flags + ndebug_flag
-                    config.build_settings['OTHER_CFLAGS'] = "$(inherited)" + ndebug_flag
+                    current_cflags = config.build_settings['OTHER_CFLAGS'] != nil ? config.build_settings['OTHER_CFLAGS'] : "$(inherited)"
+                    config.build_settings['OTHER_CFLAGS'] = current_cflags + ndebug_flag
                 end
             end
         end
diff --git a/scripts/cocoapods/utils.rb b/scripts/cocoapods/utils.rb
index d7a54cb8d18e32..a4198ef88fe176 100644
--- a/scripts/cocoapods/utils.rb
+++ b/scripts/cocoapods/utils.rb
@@ -54,7 +54,7 @@ def self.turn_off_resource_bundle_react_core(installer)
     end
 
     def self.exclude_i386_architecture_while_using_hermes(installer)
-        projects = self.exrtract_projects(installer)
+        projects = self.extract_projects(installer)
 
         # Hermes does not support `i386` architecture
         excluded_archs_default = self.has_pod(installer, 'hermes-engine') ? "i386" : ""
@@ -70,7 +70,7 @@ def self.exclude_i386_architecture_while_using_hermes(installer)
 
     def self.set_node_modules_user_settings(installer, react_native_path)
         Pod::UI.puts("Setting REACT_NATIVE build settings")
-        projects = self.exrtract_projects(installer)
+        projects = self.extract_projects(installer)
 
         projects.each do |project|
             project.build_configurations.each do |config|
@@ -82,7 +82,7 @@ def self.set_node_modules_user_settings(installer, react_native_path)
     end
 
     def self.fix_library_search_paths(installer)
-        projects = self.exrtract_projects(installer)
+        projects = self.extract_projects(installer)
 
         projects.each do |project|
             project.build_configurations.each do |config|
@@ -125,19 +125,7 @@ def self.apply_flags_for_fabric(installer, fabric_enabled: false)
         return if !fabric_enabled
 
         fabric_flag = "-DRN_FABRIC_ENABLED"
-        projects = self.exrtract_projects(installer)
-
-        projects.each do |project|
-            project.build_configurations.each do |config|
-                cflags = config.build_settings["OTHER_CFLAGS"] ? config.build_settings["OTHER_CFLAGS"] : "$(inherited)"
-
-                if !cflags.include?(fabric_flag)
-                    cflags = "#{cflags} #{fabric_flag}"
-                end
-                config.build_settings["OTHER_CFLAGS"] = cflags
-            end
-            project.save()
-        end
+        self.add_compiler_flag_to_project(installer, fabric_flag)
     end
 
     private
@@ -198,7 +186,7 @@ def self.detect_use_frameworks(target_definition)
     def self.update_search_paths(installer)
         return if ENV['USE_FRAMEWORKS'] == nil
 
-        projects = self.exrtract_projects(installer)
+        projects = self.extract_projects(installer)
 
         projects.each do |project|
             project.build_configurations.each do |config|
@@ -230,13 +218,69 @@ def self.update_search_paths(installer)
         end
     end
 
-    def self.exrtract_projects(installer)
+    def self.enable_hermes_profiler(installer, enable_hermes_profiler: false)
+        return if !enable_hermes_profiler
+
+        Pod::UI.puts "[Hermes Profiler] Enable Hermes Sample profiler"
+        # self.add_compiler_flag_to_project(installer, "-DRCT_REMOTE_PROFILE=1", configuration: "Release")
+        self.add_compiler_flag_to_pods(installer, "-DRCT_REMOTE_PROFILE=1", configuration: "Release")
+    end
+
+    # ========= #
+    # Utilities #
+    # ========= #
+
+    def self.extract_projects(installer)
         return installer.aggregate_targets
             .map{ |t| t.user_project }
             .uniq{ |p| p.path }
             .push(installer.pods_project)
     end
 
+    def self.add_compiler_flag_to_project(installer, flag, configuration: nil)
+        projects = self.extract_projects(installer)
+
+        projects.each do |project|
+            project.build_configurations.each do |config|
+                self.set_flag_in_config(config, flag, configuration: configuration)
+            end
+            project.save()
+        end
+    end
+
+    def self.add_compiler_flag_to_pods(installer, flag, configuration: nil)
+        installer.target_installation_results.pod_target_installation_results.each do |pod_name, target_installation_result|
+            target_installation_result.native_target.build_configurations.each do |config|
+                self.set_flag_in_config(config, flag, configuration: configuration)
+            end
+        end
+    end
+
+    def self.set_flag_in_config(config, flag, configuration: nil)
+        if configuration == nil || config.name == configuration
+            self.add_flag_for_key(config, flag, "OTHER_CFLAGS")
+            self.add_flag_for_key(config, flag, "OTHER_CPLUSPLUSFLAGS")
+        end
+    end
+
+
+    def self.add_flag_for_key(config, flag, key)
+        current_setting = config.build_settings[key] ? config.build_settings[key] : "$(inherited)"
+
+        if current_setting.kind_of?(Array)
+            current_setting = current_setting
+            .map { |s| s.gsub('"', '') }
+            .map { |s| s.gsub('\"', '') }
+            .join(" ")
+        end
+
+        if !current_setting.include?(flag)
+            current_setting = "#{current_setting} #{flag}"
+        end
+
+        config.build_settings[key] = current_setting
+    end
+
     def self.add_search_path_if_not_included(current_search_paths, new_search_path)
         if !current_search_paths.include?(new_search_path)
             current_search_paths << " #{new_search_path}"
diff --git a/scripts/react_native_pods.rb b/scripts/react_native_pods.rb
index 16439ba72f968c..aec2cdb24bb447 100644
--- a/scripts/react_native_pods.rb
+++ b/scripts/react_native_pods.rb
@@ -203,7 +203,13 @@ def use_flipper!(versions = {}, configurations: ['Debug'])
 # - installer: the Cocoapod object that allows to customize the project.
 # - react_native_path: path to React Native.
 # - mac_catalyst_enabled: whether we are running the Pod on a Mac Catalyst project or not.
-def react_native_post_install(installer, react_native_path = "../node_modules/react-native", mac_catalyst_enabled: false)
+# - enable_hermes_profiler: whether the hermes profiler should be turned on in Release mode
+def react_native_post_install(
+  installer, react_native_path = "../node_modules/react-native",
+  mac_catalyst_enabled: false,
+  enable_hermes_profiler: false
+)
+  enable_hermes_profiler = enable_hermes_profiler || ENV["ENABLE_HERMES_PROFILER"] == "1"
   ReactNativePodsUtils.turn_off_resource_bundle_react_core(installer)
 
   ReactNativePodsUtils.apply_mac_catalyst_patches(installer) if mac_catalyst_enabled
@@ -219,11 +225,13 @@ def react_native_post_install(installer, react_native_path = "../node_modules/re
   ReactNativePodsUtils.update_search_paths(installer)
   ReactNativePodsUtils.set_node_modules_user_settings(installer, react_native_path)
   ReactNativePodsUtils.apply_flags_for_fabric(installer, fabric_enabled: fabric_enabled)
+  ReactNativePodsUtils.enable_hermes_profiler(installer, enable_hermes_profiler: enable_hermes_profiler)
 
   NewArchitectureHelper.set_clang_cxx_language_standard_if_needed(installer)
   is_new_arch_enabled = ENV['RCT_NEW_ARCH_ENABLED'] == "1"
   NewArchitectureHelper.modify_flags_for_new_architecture(installer, is_new_arch_enabled)
 
+
   Pod::UI.puts "Pod install took #{Time.now.to_i - $START_TIME} [s] to run".green
 end