diff --git a/crates/cast/bin/cmd/run.rs b/crates/cast/bin/cmd/run.rs
index 7ab5ddd511f9..4b26c848ef66 100644
--- a/crates/cast/bin/cmd/run.rs
+++ b/crates/cast/bin/cmd/run.rs
@@ -10,7 +10,7 @@ use foundry_cli::{
     opts::{EtherscanOpts, RpcOpts},
     utils::{handle_traces, init_progress, TraceResult},
 };
-use foundry_common::{is_known_system_sender, shell, SYSTEM_TRANSACTION_TYPE};
+use foundry_common::{is_impersonated_tx, is_known_system_sender, shell, SYSTEM_TRANSACTION_TYPE};
 use foundry_compilers::artifacts::EvmVersion;
 use foundry_config::{
     figment::{
@@ -212,6 +212,12 @@ impl RunArgs {
 
                     configure_tx_env(&mut env, &tx.inner);
 
+                    if is_impersonated_tx(&tx.inner.inner) {
+                        // If the transaction is impersonated, we need to set the caller to the from
+                        // address Ref: https://github.com/foundry-rs/foundry/issues/9541
+                        env.tx.caller = tx.from;
+                    }
+
                     if let Some(to) = Transaction::to(tx) {
                         trace!(tx=?tx.tx_hash(),?to, "executing previous call transaction");
                         executor.transact_with_env(env.clone()).wrap_err_with(|| {
@@ -251,6 +257,12 @@ impl RunArgs {
 
             configure_tx_env(&mut env, &tx.inner);
 
+            if is_impersonated_tx(&tx.inner.inner) {
+                // If the transaction is impersonated, we need to set the caller to the from address
+                // Ref: https://github.com/foundry-rs/foundry/issues/9541
+                env.tx.caller = tx.from;
+            }
+
             if let Some(to) = Transaction::to(&tx) {
                 trace!(tx=?tx.tx_hash(), to=?to, "executing call transaction");
                 TraceResult::try_from(executor.transact_with_env(env))?
diff --git a/crates/cast/tests/cli/main.rs b/crates/cast/tests/cli/main.rs
index f2ee99009547..df9842722474 100644
--- a/crates/cast/tests/cli/main.rs
+++ b/crates/cast/tests/cli/main.rs
@@ -1,9 +1,10 @@
 //! Contains various tests for checking cast commands
 
 use alloy_chains::NamedChain;
-use alloy_network::TransactionResponse;
-use alloy_primitives::{b256, B256};
-use alloy_rpc_types::{BlockNumberOrTag, Index};
+use alloy_network::{TransactionBuilder, TransactionResponse};
+use alloy_primitives::{address, b256, Bytes, B256};
+use alloy_provider::{Provider, ProviderBuilder};
+use alloy_rpc_types::{BlockNumberOrTag, Index, TransactionRequest};
 use anvil::{EthereumHardfork, NodeConfig};
 use foundry_test_utils::{
     casttest, file, forgetest, forgetest_async,
@@ -1995,3 +1996,37 @@ forgetest_async!(cast_call_custom_chain_id, |_prj, cmd| {
         ])
         .assert_success();
 });
+
+// https://github.com/foundry-rs/foundry/issues/9541
+forgetest_async!(cast_run_impersonated_tx, |_prj, cmd| {
+    let (_api, handle) = anvil::spawn(
+        NodeConfig::test()
+            .with_auto_impersonate(true)
+            .with_eth_rpc_url(Some("https://sepolia.base.org")),
+    )
+    .await;
+
+    let http_endpoint = handle.http_endpoint();
+
+    let provider = ProviderBuilder::new().on_http(http_endpoint.parse().unwrap());
+
+    // send impersonated tx
+    let tx = TransactionRequest::default()
+        .with_from(address!("041563c07028Fc89106788185763Fc73028e8511"))
+        .with_to(address!("F38aA5909D89F5d98fCeA857e708F6a6033f6CF8"))
+        .with_input(
+            Bytes::from_str(
+                "0x60fe47b1000000000000000000000000000000000000000000000000000000000000000c",
+            )
+            .unwrap(),
+        );
+
+    let receipt = provider.send_transaction(tx).await.unwrap().get_receipt().await.unwrap();
+
+    assert!(receipt.status());
+
+    // run impersonated tx
+    cmd.cast_fuse()
+        .args(["run", &receipt.transaction_hash.to_string(), "--rpc-url", &http_endpoint])
+        .assert_success();
+});
diff --git a/crates/common/src/constants.rs b/crates/common/src/constants.rs
index 4ff3eb8d70fb..c67131585ba2 100644
--- a/crates/common/src/constants.rs
+++ b/crates/common/src/constants.rs
@@ -1,6 +1,8 @@
 //! Commonly used constants.
 
-use alloy_primitives::{address, Address};
+use alloy_consensus::Typed2718;
+use alloy_network::AnyTxEnvelope;
+use alloy_primitives::{address, Address, PrimitiveSignature, B256};
 use std::time::Duration;
 
 /// The dev chain-id, inherited from hardhat
@@ -53,6 +55,25 @@ pub fn is_known_system_sender(sender: Address) -> bool {
     [ARBITRUM_SENDER, OPTIMISM_SYSTEM_ADDRESS].contains(&sender)
 }
 
+pub fn is_impersonated_tx(tx: &AnyTxEnvelope) -> bool {
+    if let AnyTxEnvelope::Ethereum(tx) = tx {
+        return is_impersonated_sig(tx.signature(), tx.ty());
+    }
+    false
+}
+
+pub fn is_impersonated_sig(sig: &PrimitiveSignature, ty: u8) -> bool {
+    let impersonated_sig = PrimitiveSignature::from_scalars_and_parity(
+        B256::with_last_byte(1),
+        B256::with_last_byte(1),
+        false,
+    );
+    if ty != SYSTEM_TRANSACTION_TYPE && sig == &impersonated_sig {
+        return true;
+    }
+    false
+}
+
 #[cfg(test)]
 mod tests {
     use super::*;