diff --git a/.github/workflows/test.yaml b/.github/workflows/test.yaml
index 4d369c0..b6b975f 100644
--- a/.github/workflows/test.yaml
+++ b/.github/workflows/test.yaml
@@ -12,6 +12,10 @@ jobs:
       matrix:
         python-version: ['3.7', '3.10']
         galaxy-branch: ['release_22.01', 'dev']
+        exclude:
+          # this results in lengthy and expensive numpy wheel builds
+          - python-version: '3.10'
+            galaxy-branch: 'release_22.01'
     steps:
       - uses: actions/checkout@v3
       - uses: actions/setup-python@v2
diff --git a/gravity/config_manager.py b/gravity/config_manager.py
index 6db21d7..8ab5c03 100644
--- a/gravity/config_manager.py
+++ b/gravity/config_manager.py
@@ -26,6 +26,13 @@
 if "XDG_CONFIG_HOME" in os.environ:
     DEFAULT_STATE_DIR = os.path.join(os.environ["XDG_CONFIG_HOME"], "galaxy-gravity")
 
+OPTIONAL_APP_KEYS = (
+    "interactivetools_map",
+    "interactivetools_base_path",
+    "interactivetools_prefix",
+    "galaxy_url_prefix",
+)
+
 
 @contextlib.contextmanager
 def config_manager(config_file=None, state_dir=None):
@@ -158,7 +165,7 @@ def __load_config(self, gravity_config_dict, app_config):
         }
 
         # some things should only be included if set
-        for app_key in ("interactivetools_map", "galaxy_url_prefix"):
+        for app_key in OPTIONAL_APP_KEYS:
             if app_key in app_config:
                 app_config_dict[app_key] = app_config[app_key]
 
diff --git a/gravity/state.py b/gravity/state.py
index 1d8e5e2..b6c8aa1 100644
--- a/gravity/state.py
+++ b/gravity/state.py
@@ -389,16 +389,22 @@ class GalaxyGxItProxyService(Service):
         "forward_ip": "--forwardIP {settings[forward_ip]}",
         "forward_port": "--forwardPort {settings[forward_port]}",
         "reverse_proxy": "--reverseProxy",
+        "proxy_path_prefix": "--proxyPathPrefix {settings[proxy_path_prefix]}",
     }
     _command_template = "{virtualenv_bin}npx gx-it-proxy --ip {settings[ip]} --port {settings[port]}" \
                         " --sessions {settings[sessions]} {command_arguments[verbose]}" \
                         " {command_arguments[forward_ip]} {command_arguments[forward_port]}" \
-                        " {command_arguments[reverse_proxy]}"
+                        " {command_arguments[reverse_proxy]} {command_arguments[proxy_path_prefix]}"
 
     def __init__(self, *args, **kwargs):
         super().__init__(*args, **kwargs)
         # override from Galaxy config if set
         self.settings["sessions"] = self.config.app_config.get("interactivetools_map", self.settings["sessions"])
+        # this can only be set in Galaxy config
+        it_base_path = self.config.app_config.get("interactivetools_base_path", "/")
+        it_base_path = "/" + f"/{it_base_path.strip('/')}/".lstrip("/")
+        it_prefix = self.config.app_config.get("interactivetools_prefix", "interactivetool")
+        self.settings["proxy_path_prefix"] = f"{it_base_path}{it_prefix}/access/interactivetoolentrypoint"
 
     @validator("settings")
     def _validate_settings(cls, v, values):
diff --git a/pyproject.toml b/pyproject.toml
index 911626a..61595e5 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -3,3 +3,4 @@ line-length = 160
 
 [tool.pytest.ini_options]
 norecursedirs = "tests/galaxy.git/* tests/galaxy_venv"
+timeout = 300
diff --git a/tests/test_process_manager.py b/tests/test_process_manager.py
index 61b12dd..e615f11 100644
--- a/tests/test_process_manager.py
+++ b/tests/test_process_manager.py
@@ -327,7 +327,24 @@ def test_gxit_handler(default_config_manager, galaxy_yml, gxit_config, process_m
         assert gxit_config_path.exists()
         gxit_port = gxit_config["gravity"]["gx_it_proxy"]["port"]
         sessions = "database/interactivetools_map.sqlite"
-        assert f'npx gx-it-proxy --ip localhost --port {gxit_port} --sessions {sessions}' in gxit_config_path.read_text()
+        gxit_config_contents = gxit_config_path.read_text()
+        assert f'npx gx-it-proxy --ip localhost --port {gxit_port} --sessions {sessions}' in gxit_config_contents
+        assert '--proxyPathPrefix /interactivetool/access/interactivetoolentrypoint' in gxit_config_contents
+
+
+@pytest.mark.parametrize('process_manager_name', ['supervisor', 'systemd'])
+def test_gxit_handler_path_prefix(default_config_manager, galaxy_yml, gxit_config, process_manager_name):
+    state_dir = default_config_manager.state_dir
+    gxit_base_path = gxit_config["galaxy"]["interactivetools_base_path"] = "/foo/"
+    gxit_prefix = gxit_config["galaxy"]["interactivetools_prefix"] = "bar"
+    galaxy_yml.write(json.dumps(gxit_config))
+    default_config_manager.load_config_file(str(galaxy_yml))
+    with process_manager.process_manager(config_manager=default_config_manager) as pm:
+        pm.update()
+        gxit_config_path = service_conf_path(state_dir, process_manager_name, 'gx-it-proxy')
+        assert gxit_config_path.exists()
+        proxy_path_prefix = f'{gxit_base_path}{gxit_prefix}/access/interactivetoolentrypoint'
+        assert f'--proxyPathPrefix {proxy_path_prefix}' in gxit_config_path.read_text()
 
 
 @pytest.mark.parametrize('process_manager_name', ['supervisor', 'systemd'])
diff --git a/tox.ini b/tox.ini
index 1e88aff..8ac6e5a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -14,6 +14,7 @@ commands =
 deps = 
   lint: flake8
   test: pytest
+  test: pytest-timeout
   test: coverage
   test: requests
 passenv =