diff --git a/java-life-sciences/CHANGELOG.md b/java-life-sciences/CHANGELOG.md
index 7bb38716735d..f94bfea50633 100644
--- a/java-life-sciences/CHANGELOG.md
+++ b/java-life-sciences/CHANGELOG.md
@@ -1,5 +1,12 @@
 # Changelog
 
+## [0.4.1](https://github.com/googleapis/java-life-sciences/compare/v0.4.0...v0.4.1) (2022-06-23)
+
+
+### Dependencies
+
+* update dependency com.google.cloud:google-cloud-shared-dependencies to v2.13.0 ([#195](https://github.com/googleapis/java-life-sciences/issues/195)) ([b8c64ea](https://github.com/googleapis/java-life-sciences/commit/b8c64ea802b50c41fb7da67a8efe8eca5d9ccd0a))
+
 ## [0.4.0](https://github.com/googleapis/java-life-sciences/compare/v0.3.10...v0.4.0) (2022-05-20)
 
 
diff --git a/java-life-sciences/google-cloud-life-sciences-bom/pom.xml b/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
index 528462fd7c99..659395ab1367 100644
--- a/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
+++ b/java-life-sciences/google-cloud-life-sciences-bom/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-bom</artifactId>
-  <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>pom</packaging>
   <parent>
     <groupId>com.google.cloud</groupId>
@@ -56,17 +56,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.4.1</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.4.1</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
     </dependencies>
   </dependencyManagement>
diff --git a/java-life-sciences/google-cloud-life-sciences/pom.xml b/java-life-sciences/google-cloud-life-sciences/pom.xml
index 902bfd699069..470a910cdd8a 100644
--- a/java-life-sciences/google-cloud-life-sciences/pom.xml
+++ b/java-life-sciences/google-cloud-life-sciences/pom.xml
@@ -3,7 +3,7 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences</artifactId>
-  <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <packaging>jar</packaging>
   <name>Google Cloud Life Sciences</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
@@ -11,7 +11,7 @@
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <properties>
     <site.installationModule>google-cloud-life-sciences</site.installationModule>
diff --git a/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml b/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
index 8095670d4d58..23ef5c6bf232 100644
--- a/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
+++ b/java-life-sciences/grpc-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.4.1</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
   <name>grpc-google-cloud-life-sciences-v2beta</name>
   <description>GRPC library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/java-life-sciences/pom.xml b/java-life-sciences/pom.xml
index 513feedbd34c..6ec1df48c81b 100644
--- a/java-life-sciences/pom.xml
+++ b/java-life-sciences/pom.xml
@@ -4,7 +4,7 @@
   <groupId>com.google.cloud</groupId>
   <artifactId>google-cloud-life-sciences-parent</artifactId>
   <packaging>pom</packaging>
-  <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+  <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   <name>Google Cloud Life Sciences Parent</name>
   <url>https://github.com/googleapis/java-life-sciences</url>
   <description>
@@ -60,17 +60,17 @@
       <dependency>
         <groupId>com.google.cloud</groupId>
         <artifactId>google-cloud-life-sciences</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+        <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>grpc-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.4.1</version><!-- {x-version-update:grpc-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
       <dependency>
         <groupId>com.google.api.grpc</groupId>
         <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-        <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+        <version>0.4.1</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
       </dependency>
 
       <dependency>
diff --git a/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml b/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
index 969fc193886d..b09f4a6f66af 100644
--- a/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
+++ b/java-life-sciences/proto-google-cloud-life-sciences-v2beta/pom.xml
@@ -4,13 +4,13 @@
   <modelVersion>4.0.0</modelVersion>
   <groupId>com.google.api.grpc</groupId>
   <artifactId>proto-google-cloud-life-sciences-v2beta</artifactId>
-  <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
+  <version>0.4.1</version><!-- {x-version-update:proto-google-cloud-life-sciences-v2beta:current} -->
   <name>proto-google-cloud-life-sciences-v2beta</name>
   <description>Proto library for google-cloud-life-sciences</description>
   <parent>
     <groupId>com.google.cloud</groupId>
     <artifactId>google-cloud-life-sciences-parent</artifactId>
-    <version>0.4.1-SNAPSHOT</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
+    <version>0.4.1</version><!-- {x-version-update:google-cloud-life-sciences:current} -->
   </parent>
   <dependencies>
     <dependency>
diff --git a/java-life-sciences/versions.txt b/java-life-sciences/versions.txt
index 6b6f67dd94ff..e09a32aba7ac 100644
--- a/java-life-sciences/versions.txt
+++ b/java-life-sciences/versions.txt
@@ -1,6 +1,6 @@
 # Format:
 # module:released-version:current-version
 
-google-cloud-life-sciences:0.4.0:0.4.1-SNAPSHOT
-grpc-google-cloud-life-sciences-v2beta:0.4.0:0.4.1-SNAPSHOT
-proto-google-cloud-life-sciences-v2beta:0.4.0:0.4.1-SNAPSHOT
+google-cloud-life-sciences:0.4.1:0.4.1
+grpc-google-cloud-life-sciences-v2beta:0.4.1:0.4.1
+proto-google-cloud-life-sciences-v2beta:0.4.1:0.4.1