diff --git a/ibis/expr/datatypes/core.py b/ibis/expr/datatypes/core.py
index 2d7796c7272e..9c89c7fc85fa 100644
--- a/ibis/expr/datatypes/core.py
+++ b/ibis/expr/datatypes/core.py
@@ -20,7 +20,6 @@
     map_to,
     validator,
 )
-from ibis.util import deprecated, warn_deprecated
 
 dtype = Dispatcher('dtype')
 
diff --git a/ibis/expr/schema.py b/ibis/expr/schema.py
index 74a56014b96e..9afe2aa6f854 100644
--- a/ibis/expr/schema.py
+++ b/ibis/expr/schema.py
@@ -1,7 +1,7 @@
 from __future__ import annotations
 
 import collections
-from typing import TYPE_CHECKING, Iterable, Iterator, Mapping
+from typing import TYPE_CHECKING, Iterable, Iterator
 
 from multipledispatch import Dispatcher
 
@@ -10,7 +10,7 @@
 from ibis.common.exceptions import IntegrityError
 from ibis.common.grounds import Concrete
 from ibis.common.validators import frozendict_of, instance_of, validator
-from ibis.util import deprecated, indent, warn_deprecated
+from ibis.util import indent
 
 if TYPE_CHECKING:
     import pandas as pd
@@ -50,30 +50,6 @@ class Schema(Concrete):
     """A mapping of [`str`][str] to [`DataType`][ibis.expr.datatypes.DataType] objects
     representing the type of each column."""
 
-    @classmethod
-    def __create__(cls, names, types=None):
-        if types is None:
-            return super().__create__(fields=names)
-        else:
-            warn_deprecated(
-                "Schema(names, types)",
-                as_of="4.1",
-                removed_in="5.0",
-                instead=(
-                    "construct a Schema using a mapping of names to types instead: "
-                    "Schema(dict(zip(names, types)))"
-                ),
-            )
-            return schema(names, types)
-
-    def __reduce__(self):
-        return (self.__class__, (self.fields, None))
-
-    def copy(self, fields=None):
-        if fields is None:
-            fields = self.fields
-        return type(self)(fields)
-
     def __repr__(self) -> str:
         space = 2 + max(map(len, self.names), default=0)
         return "ibis.Schema {{{}\n}}".format(
@@ -133,37 +109,6 @@ def equals(self, other: Schema) -> bool:
             )
         return self.__cached_equals__(other)
 
-    @deprecated(
-        as_of="4.1",
-        removed_in="5.0",
-        instead="construct a new Schema without the undesired names instead",
-    )
-    def delete(self, names_to_delete: Iterable[str]) -> Schema:
-        """Remove `names_to_delete` names from `self`.
-
-        Parameters
-        ----------
-        names_to_delete
-            Iterable of `str` to remove from the schema.
-
-        Examples
-        --------
-        >>> import ibis
-        >>> sch = ibis.schema({"a": "int", "b": "string"})
-        >>> sch.delete({"a"})
-        ibis.Schema {
-          b  string
-        }
-        """
-        for name in names_to_delete:
-            if name not in self:
-                raise KeyError(name)
-
-        delete = frozenset(names_to_delete)
-        fields = {k: v for k, v in self.fields.items() if k not in delete}
-
-        return self.__class__(fields)
-
     @classmethod
     def from_tuples(
         cls,
@@ -192,36 +137,6 @@ def from_tuples(
         """
         return cls(dict(values))
 
-    @classmethod
-    @deprecated(
-        as_of="4.1",
-        removed_in="5.0",
-        instead="directly construct a Schema instead",
-    )
-    def from_dict(cls, dictionary: Mapping[str, str | dt.DataType]) -> Schema:
-        """Construct a `Schema` from a `Mapping`.
-
-        Parameters
-        ----------
-        dictionary
-            Mapping from which to construct a `Schema` instance.
-
-        Returns
-        -------
-        Schema
-            A new schema
-
-        Examples
-        --------
-        >>> import ibis
-        >>> ibis.Schema.from_dict({"a": "int", "b": "string"})
-        ibis.Schema {
-          a  int64
-          b  string
-        }
-        """
-        return cls(dictionary)
-
     def to_pandas(self):
         """Return the equivalent pandas datatypes."""
         from ibis.backends.pandas.client import ibis_schema_to_pandas
@@ -245,10 +160,6 @@ def __ge__(self, other: Schema) -> bool:
         """Return whether `self` is a superset of or equal to `other`."""
         return set(self.items()) >= set(other.items())
 
-    @deprecated(as_of="4.1", removed_in="5.0", instead="use Schema.merge() instead")
-    def append(self, other: Schema) -> Schema:
-        return self.merge(other)
-
     def merge(self, other: Schema) -> Schema:
         """Merge `other` to `self`.
 
diff --git a/ibis/tests/expr/test_schema.py b/ibis/tests/expr/test_schema.py
index 236cf439d615..2a17ab01795c 100644
--- a/ibis/tests/expr/test_schema.py
+++ b/ibis/tests/expr/test_schema.py
@@ -137,11 +137,10 @@ def test_whole_schema():
 
 
 def test_schema_names_and_types_length_must_match():
-    with pytest.raises(IntegrityError), pytest.warns(FutureWarning):
-        sch.Schema(names=["a", "b"], types=["int", "str", "float"])
+    with pytest.raises(IntegrityError):
+        sch.schema(["a", "b"], ["int", "str", "float"])
 
-    with pytest.warns(FutureWarning):
-        schema = sch.Schema(names=["a", "b"], types=["int", "str"])
+    schema = sch.schema(["a", "b"], ["int", "str"])
 
     assert isinstance(schema, sch.Schema)
     assert schema.names == ("a", "b")
@@ -213,11 +212,3 @@ def test_api_accepts_schema_objects():
 def test_names_types():
     s = ibis.schema(names=["a"], types=["array<float64>"])
     assert s == ibis.schema(dict(a="array<float64>"))
-
-
-def test_schema_delete():
-    s1 = ibis.schema({"a": "int64", "b": "string", "c": "float64", "d": "int64"})
-    with pytest.warns(FutureWarning):
-        s2 = s1.delete(["b", "d"])
-
-    assert s2 == ibis.schema({"a": "int64", "c": "float64"})