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qcML.obo
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format-version: 1.2
data-version: 0.1.2
date: 26:11:2015 09:52
saved-by: Mathias Walzer
remark: creator: Mathias Walzer <walzer <-at-> informatik.uni-tuebingen.de>
remark: creator: Lucia Espona Pernas <espona <-at-> imsb.biol.ethz.ch>
remark: creator: Marc Sturm <marc.sturm <-at-> med.uni-tuebingen.de>
import: http://unit-ontology.googlecode.com/svn/trunk/unit.obo
import: http://psidev.cvs.sourceforge.net/viewvc/psidev/psi/psi-ms/mzML/controlledVocabulary/psi-ms.obo
default-namespace: QC
remark: namespace: QC
remark: version: 0.1.1
ontology: uo
ontology: ms
[Typedef]
id: has_regexp
name: has regexp
[Typedef]
id: has_units
name: has_units
[Typedef]
id: part_of
name: part_of
is_transitive: true
[Typedef]
id: has_order
name: has_order
################################################################################################################################################
# MASS SPECTROMETRY QC PARAMETERS - NAMESPACE QC:0000001...
################################################################################################################################################
[Term]
id: QC:0000001
name: quality parameter
def: "A quality parameter of some sort." [PXS:QC]
[Term]
id: QC:0000002
name: run quality parameter
def: "A run quality parameter of some sort." [PXS:QC]
is_a: QC:0000001 ! quality parameter
[Term]
id: QC:0000003
name: set quality parameter
def: "A set quality parameter of some sort." [PXS:QC]
is_a: QC:0000001 ! quality parameter
[Term]
id: QC:0000004
name: MS acquisition result details
def: "The results (e.g. counts) of the MS acquisition step of a MS experiment." [PXS:QC]
is_a: QC:0000001 ! quality parameter
remark: run name is MS:1000577 as raw data file in [PSI:MS]
[Term]
id: QC:0000005
name: set name
def: "The set name describing the set grouping." [PXS:QC]
is_a: QC:0000001 ! quality parameter
[Term]
id: QC:0000006
name: MS1 spectra count
def: "Contains the number of MS1 spectra recorded." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
[Term]
id: QC:0000007
name: MS2 spectra count
def: "Contains the number of MS2 spectra recorded." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
[Term]
id: QC:0000008
name: Chromatogram count
def: "Contains the number of chromatograms recorded." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
[Term]
id: QC:0000009
name: MS MZ acquisition ranges
def: "Contains the min/max MZ range boundaries observed during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
is_a: QC:0000048 ! value table
[Term]
id: QC:0000010
name: MS min MZ
def: "Contains the actual min MZ occurrence in MS acquisition." [PXS:QC]
is_a: QC:0000009 ! MS MZ acquisition ranges
remark: supposed as table col
[Term]
id: QC:0000011
name: MS max MZ
def: "Contains the actual max MZ occurrence in MS acquisition." [PXS:QC]
is_a: QC:0000009 ! MS MZ acquisition ranges
remark: supposed as table col
[Term]
id: QC:0000012
name: MS RT acquisition ranges
def: "Contains the min/max RT range boundaries observed during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
is_a: QC:0000048 ! value table
[Term]
id: QC:0000013
name: MS min RT
def: "Contains the actual min RT occurrence in MS acquisition." [PXS:QC]
is_a: QC:0000012 ! MS RT acquisition ranges
is_a: QC:0000048 ! value table
[Term]
id: QC:0000014
name: MS max RT
def: "Contains the actual max RT occurrence in MS acquisition." [PXS:QC]
is_a: QC:0000012 ! MS RT acquisition ranges
remark: supposed as table col
[Term]
id: QC:0000015
name: MS gradient settings
def: "Contains the min/max RT range boundaries used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000012 ! MS RT acquisition ranges
is_a: QC:0000048 ! value table
[Term]
id: QC:0000016
name: MS MZ detection settings
def: "Contains the min/max MZ range boundaries used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000009 ! MS MZ acquisition ranges
[Term]
id: QC:0000017
name: MS1 injection time
def: "Contains the accumulation time in the ion trap device used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
relationship: has_units UO:0000010 ! second
relationship: has_units UO:0000031 ! minute
[Term]
id: QC:0000018
name: MS2 injection time
def: "Contains the accumulation time in the ion trap device used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
relationship: has_units UO:0000010 ! second
relationship: has_units UO:0000031 ! minute
[Term]
id: QC:0000019
name: MS1 scan time
def: "Contains the average scan time for a MS1 event used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
relationship: has_units UO:0000010 ! second
relationship: has_units UO:0000031 ! minute
[Term]
id: QC:0000020
name: MS2 scan time
def: "Contains the average scan time for a MS2 event used in machine settings during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
relationship: has_units UO:0000010 ! second
relationship: has_units UO:0000031 ! minute
[Term]
id: QC:0000021
name: lock mass percentage
def: "Contains the percentage of found lock masses during MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
[Term]
id: QC:0000022
name: TICs
def: "The total ion currents detected in each of a series of mass spectra recorded." [PXS:QC]
is_a: QC:0000048 ! value table
[Term]
id: QC:0000023
name: TIC slump
def: "The percentage of tic slumps below 10k." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
remark: TIC plot is MS:1000235
[Term]
id: QC:0000024
name: detector-saturation
def: "The average ion saturation of the detector in MS acquisition." [PXS:QC]
is_a: QC:0000004 ! MS acquisition result details
[Term]
id: QC:0000025
name: MS identification result details
def: "The results (e.g. identifications) of the MS identification step of a MS experiment." [PXS:QC]
is_a: QC:0000001 ! quality parameter
[Term]
id: QC:0000026
name: MS id settings
def: "The settings of the search engine used engine name and further parameters." [PXS:QC]
is_a: MS:1001249 ! search input details
[Term]
id: QC:0000027
name: precursor ion tolerance
def: "This parameter shows the precursor tolerance that was used for MS/MS identification." [PXS:QC]
is_a: MS:1001411 ! search tolerance specification
[Term]
id: QC:0000028
name: product ion tolerance
def: "This parameter shows the product ion tolerance that was used for MS/MS identification." [PXS:QC]
is_a: MS:1001411 ! search tolerance specification
[Term]
id: QC:0000029
name: total number of PSMs
def: "This number indicates the number of spectra that were given peptide annotations." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000030
name: total number of identified peptides
def: "This number indicates the number peptides that were identified." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000031
name: total number of uniquely identified peptides
def: "This number indicates the number peptides that were uniquely identified." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000032
name: total number of identified proteins
def: "This number indicates the number proteins that were identified." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000033
name: total number of uniquely identified proteins
def: "This number indicates the number proteins that were uniquely identified." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000034
name: total number of modified peptides
def: "This number indicates the number modified peptide sequences that were identified (after FDR)." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000035
name: id ratio
def: "This ratio indicates the number of identified peptides vs. the number of recorded ms2 spectra." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000036
name: id coverage
def: "The coverages of distinct sequences for a respective engine." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000037
name: total number of missed cleavages
def: "This number indicates the number missed cleavages that were identified." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000038
name: mass accuracy
def: "The values of overall mass accuracy." [PXS:QC]
is_a: MS:1001105 ! peptide result details
is_a: QC:0000025 ! MS identification result details
is_a: QC:0000048 ! value table
[Term]
id: QC:0000039
name: delta ppm
def: "The deviation of the precursor ion mass and the theoretical mass of the matched identification." [PXS:QC]
relationship: has_units UO:0000169 ! parts per million
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000040
name: mean delta ppm
def: "The mean deviation of the precursor ion masses and the theoretical masses of the matched identifications." [PXS:QC]
relationship: has_units UO:0000169 ! parts per million
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000041
name: median delta ppm
def: "The median deviation of the precursor ion masses and the theoretical masses of the matched identifications." [PXS:QC]
relationship: has_units UO:0000169 ! parts per million
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000042
name: enzyme contamination
def: "The ratio of the sum of chymotryptic and tryptic sequences by the number of tryptic sequences." [PXS:QC]
relationship: has_units UO:0000169 ! parts per million ratio NA
is_a: QC:0000025 ! MS identification result details
[Term]
id: QC:0000043
name: fractional masses plot
def: "This plot visualizes the theoretical fractional masses (e.g. from the search DB input) vs. the measured fractional masses." [PXS:QC]
is_a: QC:0000050 ! image plot
[Term]
id: QC:0000044
name: precursors
def: "The table of measured precursor ions over RT/mz." [PXS:QC]
is_a: QC:0000048 ! value table
[Term]
id: QC:0000045
name: MS quantification result details
def: "The results (e.g. number of features) of the MS quantification step of a MS experiment." [PXS:QC]
is_a: QC:0000001 ! quality parameter
[Term]
id: QC:0000046
name: number of features
def: "The number of features reported." [PXS:QC]
is_a: QC:0000045 ! MS quantification result details
[Term]
id: QC:0000047
name: features
def: "The tables of features over RT/mz." [PXS:QC]
is_a: QC:0000048 ! value table
is_a: QC:0000045 ! MS quantification result details
[Term]
id: QC:0000048
name: value table
def: "The table contains generic information." [PXS:QC]
[Term]
id: QC:0000049
name: generic table
def: "The table contains generic information." [PXS:QC]
is_a: QC:0000048 ! value table
[Term]
id: QC:0000050
name: image plot
def: "The plot contains generic information." [PXS:QC]
[Term]
id: QC:0000051
name: generic plot
def: "The plot contains generic information." [PXS:QC]
is_a: QC:0000050 ! image plot
[Term]
id: QC:0000052
name: id ratio plot
def: "This plot visualizes the ratio of number of identified peptides vs. the number of recorded ms2 spectra." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000050 ! image plot
[Term]
id: QC:0000053
name: mass accuracy plot
def: "This plot visualizes the mass accuracy of identified ms2 spectra." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000050 ! image plot
[Term]
id: QC:0000054
name: mass accuracy over time plot
def: "This plot visualizes the mass accuracy over the course of RT." [PXS:QC]
is_a: MS:1001405 ! spectrum identification result details
is_a: QC:0000050 ! image plot
[Term]
id: QC:0000055
name: MS experiment heatmap
def: "This plot visualizes the intensities on RT vs mz." [PXS:QC]
is_a: QC:0000050 ! image plot
################################################################################################################################################
# META DATA PARAMETERS - NAMESPACE QC:1000001...
################################################################################################################################################
[Term]
id: QC:1000001
name: meta data parameter
def: "A meta data parameter, i.e. it describes how/when the quality parameters were created." [PXS:QC]
created_by: sturm
[Term]
id: QC:1000002
name: creation software
def: "Software used for QC calculation (name and version)." [PXS:QC]
is_a: QC:1000001 ! meta data parameter
xref: value-type:xsd\:string "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:1000003
name: creation software parameters
def: "Command-line parameters of the creation software that are relevant for QC calculation." [PXS:QC]
is_a: QC:1000001 ! meta data parameter
xref: value-type:xsd\:string "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:1000004
name: creation date
def: "Date and time when the quality parameters were calculation." [PXS:QC]
is_a: QC:1000001 ! meta data parameter
xref: value-type:xsd\:datetime "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:1000005
name: source file
def: "Input file that contains raw data for quality parameter calculation." [PXS:QC]
is_a: QC:1000001 ! meta data parameter
xref: value-type:xsd\:string "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:1000006
name: linked file
def: "Link to a file. For source files use term QC:1000005." [PXS:QC]
is_a: QC:1000001 ! meta data parameter
xref: value-type:xsd\:anyURI "The allowed value-type for this CV term."
created_by: schroeder
################################################################################################################################################
# NEXT GENERATION SEQUENCING QC PARAMETERS - NAMESPACE QC:2000001...
################################################################################################################################################
[Term]
id: QC:2000001
name: NGS quality parameter
def: "Quality parameter from a next generation sequencing experiment." [PXS:QC]
is_a: QC:0000001 ! quality parameter
created_by: sturm
[Term]
id: QC:2000002
name: NGS aquisition parameter
def: "Quality parameter from the acquisition step of a next generation sequencing experiment. This includes the raw read data before any manipulation." [PXS:QC]
is_a: QC:2000001 ! NGS quality parameter
created_by: sturm
[Term]
id: QC:2000003
name: NGS mapping parameter
def: "Quality parameter from the mapping/alignment step of a next generation sequencing experiment." [PXS:QC]
is_a: QC:2000001 ! NGS quality parameter
created_by: sturm
[Term]
id: QC:2000004
name: NGS variant list parameter
def: "Quality parameter from the small variant calling step of a next generation sequencing experiment." [PXS:QC]
is_a: QC:2000001 ! NGS quality parameter
created_by: sturm
[Term]
id: QC:2000005
name: read count
def: "Total number of reads (one cluster in a paired-end experiment generates two reads)." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000006
name: read length
def: "Raw read length of a single read before trimming. Comma-separated list of lengths if several." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:string "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000007
name: Q20 read percentage
def: "The percentage of reads with a mean base quality score greater than Q20." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000008
name: Q30 base percentage
def: "The percentage of bases with a minimum quality score of Q30." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000009
name: no base call percentage
def: "The percentage of bases without base call (N)." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000010
name: gc content percentage
def: "The percentage of bases that are called to be G or C." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000011
name: base distribution plot
def: "Plots the base content in percent against the cycle. Bases might for example be A,C,G,T,N and GC." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000012
name: Q score plot
def: "Plots the mean forward/reverse Q score for each cycle." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000013
name: variant count
def: "Total number of variants in the target region." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000014
name: known variants percentage
def: "Percentage of variants that are known polymorphisms in the dbSNP database." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000015
name: high-impact variants percentage
def: "Percentage of variants with high impact on the protein, i.e. stop-gain, stop-loss, frameshift, splice-acceptor or splice-donor variants." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000016
name: homozygous variants percentage
def: "Percentage of variants that are called as homozygous." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000017
name: indel variants percentage
def: "Percentage of variants that are insertions/deletions." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000018
name: transition/transversion ratio
def: "Transition/transversion ratio of single nucleotide variants." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000019
name: trimmed base percentage
def: "Percentage of bases that were trimmed during to adapter or quality trimming."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000020
name: mapped read percentage
def: "Percentage of reads that could be mapped to the reference genome."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000021
name: on-target read percentage
def: "Percentage of reads that could be mapped to the target region."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000022
name: properly-paired read percentage
def: "Percentage of properly paired reads (for paired-end reads only)."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000023
name: insert size
def: "Average insert size (for paired-end reads only)."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000024
name: duplicate read percentage
def: "Percentage of reads removed because they were duplicates (PCR, optical, etc)."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000025
name: target region read depth
def: "Average sequencing depth in target region."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000026
name: target region 10x percentage
def: "Percentage of the target region that is covered at least 10-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000027
name: target region 20x percentage
def: "Percentage of the target region that is covered at least 20-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000028
name: target region 30x percentage
def: "Percentage of the target region that is covered at least 30-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000029
name: target region 50x percentage
def: "Percentage of the target region that is covered at least 50-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000030
name: target region 100x percentage
def: "Percentage of the target region that is covered at least 100-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000031
name: target region 200x percentage
def: "Percentage of the target region that is covered at least 200-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000032
name: target region 500x percentage
def: "Percentage of the target region that is covered at least 500-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000033
name: error estimation read depth
def: "Average read depth on the special target region used for error estimation after mapping."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
is_obsolete: true
[Term]
id: QC:2000034
name: error estimation N percentage
def: "No base call (N) percentage determined on special target region after mapping."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
is_obsolete: true
[Term]
id: QC:2000035
name: error estimation SNV percentage
def: "SNV error percentage determined on special target region after mapping."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
is_obsolete: true
[Term]
id: QC:2000036
name: error estimation indel percentage
def: "indel error percentage determined on special target region after mapping."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
is_obsolete: true
[Term]
id: QC:2000037
name: depth distribution plot
def: "Plots the depth of coverage against the percentage of the target region coverated at the specific depth." [PXS:QC]
is_a: QC:2000003 ! NGS mapping parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000038
name: insert size distribution plot
def: "Plots the paired-end insert size against the number of reads with the specific insert size." [PXS:QC]
is_a: QC:2000003 ! NGS mapping parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000039
name: gender check
def: "Gender check result: 'n/a', 'male_passed', 'male_failed', 'female_passed', 'female_failed'."
is_a: QC:2000001 ! NGS quality parameter
xref: value-type:xsd\:string "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000040
name: sample correlation
def: "Correlation of high-quality SNV genotypes between tumor and normal sample."
is_a: QC:2000125 ! NGS somatic parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000041
name: somatic variant count
def: "Total number of somatic variants in the target region."
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000042
name: somatic indel variants percentage
def: "Percentage of somatic variants that are insertions/deletions." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000043
name: somatic transition/transversion ratio
def: "Transition/transversion ratio of somatic single nucleotide variants." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000044
name: somatic CNVs count
def: "Count of large somatic CNVs." [PXS:QC]
is_a: QC:2000125 ! NGS somatic parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000045
name: known somatic variants percentage
def: "Percentage of somatic variants that are listed as germline variants in public datbases (e.g. AF>1% in gnomAD)." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000046
name: somatic variant distance plot
def: "Plots the distance of somatic variants over the genomic position. Over the target region." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000047
name: somatic variant signature plot
def: "Percentage of different variant types. If a target file was given, the variant type percentage is normalized to the reference genome." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000048
name: somatic variants allele frequencies plot
def: "Plots the allele frequencies of covered dbSNP variants over the genomic position." [PXS:QC]
is_a: QC:2000125 ! NGS somatic parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000049
name: bases sequenced (MB)
def: "Bases sequenced in total (in megabases)." [PXS:QC]
is_a: QC:2000002 ! NGS aquisition parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000050
name: bases usable (MB)
def: "Bases sequenced that are usable for variant calling (in megabases)." [PXS:QC]
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000051
name: SNV allele frequency deviation
def: "Percentage of common SNPs that deviate from the expected allele frequency (i.e. 0.0, 0.5 or 1.0 for diploid organisms)." [PXS:QC]
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000052
name: clipped base percentage
def: "Percentage of the bases that are soft-clipped or hand-clipped during mapping." [PXS:QC]
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000053
name: somatic variant rate
def: "Categorized somatic variant rate followed by the somatic variant rate [variants/Mbp] normalized for the target region and exome size and corrected for tumor suppressors." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000054
name: tumor content estimate
def: "Estimate of tumor content." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000055
name: somatic SNVs allele frequency histogram
def: "Allele frequency histogram of somatic SNVs." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: schroeder
[Term]
id: QC:2000056
name: somatic SNV mutation types
def: "Histogram of somatic point mutation types." [PXS:QC]
is_a: QC:2000004 ! NGS variant list parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000057
name: near-target read percentage
def: "Percentage of reads that were mapped to the target region or near the target region (at most 250 bases away)."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000058
name: target region half depth percentage
def: "Percentage of the target region that is covered at least with half of the target region average depth. This is a measure of coverage uniformity."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000059
name: AT dropout
def: "Illumina-style AT dropout metric. Calculated by taking each GC bin independently and calculating (%ref_at_gc - %reads_at_gc) and summing all positive values for GC=[0..50]."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000060
name: GC dropout
def: "Illumina-style GC dropout metric. Calculated by taking each GC bin independently and calculating (%ref_at_gc - %reads_at_gc) and summing all positive values for GC=[50..100]."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000061
name: GC bias plot
def: "Plots the percentage of target regions and reads per GC bin [0-100]." [PXS:QC]
is_a: QC:2000002 ! NGS mapping parameter
is_a: QC:0000050 ! image plot
xref: value-type:xsd\:base64Binary "The allowed value-type for this CV term."
created_by: sturm
[Term]
id: QC:2000062
name: somatic LOH events
def: "Count of large somatic LOHs events (that do not touch centromeres)." [PXS:QC]
is_a: QC:2000125 ! NGS somatic parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: gschwind
[Term]
id: QC:2000063
name: telomer allelic imbalance
def: "Count of somatic telomer allelic imbalance (TAI) events." [PXS:QC]
is_a: QC:2000125 ! NGS somatic parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: gschwind
[Term]
id: QC:2000064
name: long state transition
def: "Count of somatic long state transition (LST) events." [PXS:QC]
is_a: QC:2000125 ! NGS somatic parameter
xref: value-type:xsd\:int "The allowed value-type for this CV term."
created_by: gschwind
[Term]
id: QC:2000065
name: target region 1000x percentage
def: "Percentage of the target region that is covered at least 1000-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schuetz
[Term]
id: QC:2000066
name: target region 2500x percentage
def: "Percentage of the target region that is covered at least 2500-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schuetz
[Term]
id: QC:2000067
name: target region 5000x percentage
def: "Percentage of the target region that is covered at least 5000-fold."
is_a: QC:2000003 ! NGS mapping parameter
xref: value-type:xsd\:float "The allowed value-type for this CV term."
created_by: schuetz
[Term]