notebooks/06.03-TCLab PCR UI Development.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {
    "colab_type": "text",
    "id": "xbd14rTT20VF"
   },
   "source": [
    "# PCR Thermal Cycler UI Development\n",
    "\n",
    "Information from [ThermoFisher Scientific](https://www.thermofisher.com/us/en/home/life-science/cloning/cloning-learning-center/invitrogen-school-of-molecular-biology/pcr-education/pcr-reagents-enzymes/pcr-cycling-considerations.html)."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {
    "colab": {},
    "colab_type": "code",
    "id": "7JROS9Vm2zRR"
   },
   "outputs": [],
   "source": [
    "%matplotlib inline\n",
    "\n",
    "import ipywidgets as widgets\n",
    "from IPython.display import display\n",
    "import numpy as np\n",
    "import matplotlib.pyplot as plt\n",
    "import pandas as pd\n",
    "\n",
    "def PCR_thermal_cycle(filename):\n",
    "\n",
    "    filename_text = widgets.Text(value=filename, description=\"Filename\")\n",
    "\n",
    "    heat_rate_label = widgets.Label('Heat Rate [deg C/sec]', layout=widgets.Layout(width='140px'))\n",
    "    heat_rate = widgets.FloatSlider(value = 0.5, min=0.1, max=2, step=0.01)\n",
    "    \n",
    "    cool_rate_label = widgets.Label('Cool Rate [deg C/sec]', layout=widgets.Layout(width='140px'))\n",
    "    cool_rate = widgets.FloatSlider(value = 0.5, min=0.1, max=2, step=0.01)\n",
    "    \n",
    "    pcr_cycles_label = widgets.Label('PCR Cycles', layout=widgets.Layout(width='140px'))\n",
    "    pcr_cycles = widgets.IntSlider(value=12, min=1, max=30)\n",
    "\n",
    "    denaturation_label = widgets.Label('Denaturation', layout=widgets.Layout(width='80px'))\n",
    "    denaturation_temp = widgets.FloatSlider(value=94, min=90, max=98, step=0.1, description='Temperature', readout_format='0.1f')\n",
    "    denaturation_dur = widgets.BoundedIntText(value=60, min=30, max=120, step=1, description='Duration')\n",
    "    denaturation = widgets.HBox([denaturation_label, denaturation_temp, denaturation_dur])\n",
    "\n",
    "    annealing_label = widgets.Label('Annealing', layout=widgets.Layout(width='80px'))\n",
    "    annealing_temp = widgets.FloatSlider(value=64, min=55, max=70, step=0.1, description='Temperature', readout_format='0.1f')\n",
    "    annealing_dur = widgets.BoundedIntText(value=60, min=20, max=120, step=1, description='Duration')\n",
    "    annealing = widgets.HBox([annealing_label, annealing_temp, annealing_dur])\n",
    "\n",
    "    extension_label = widgets.Label('Extension', layout=widgets.Layout(width='80px'))\n",
    "    extension_temp = widgets.FloatSlider(value=70, min=68, max=72, step=0.1, description='Temperature', readout_format='0.1f')\n",
    "    extension_dur = widgets.BoundedIntText(value=20, min=10, max=120, step=1, description='Duration')\n",
    "    extension = widgets.HBox([extension_label, extension_temp, extension_dur])\n",
    "\n",
    "    def create_setpoint_trajectory(filename_text, heat_rate, cool_rate, pcr_cycles, denaturation_temp,\n",
    "            denaturation_dur, annealing_temp, annealing_dur, extension_temp, extension_dur):\n",
    "        Ta = 22\n",
    "        tp = [0]\n",
    "        Tp = [Ta]   \n",
    "\n",
    "        for k in range(0, pcr_cycles):\n",
    "            # denaturation\n",
    "            tp.append(tp[-1] + (denaturation_temp - Tp[-1]) / heat_rate)\n",
    "            Tp.append(denaturation_temp)\n",
    "            tp.append(tp[-1] + denaturation_dur)\n",
    "            Tp.append(denaturation_temp)\n",
    "\n",
    "            # annealing\n",
    "            tp.append(tp[-1] - (annealing_temp - denaturation_temp) / cool_rate)\n",
    "            Tp.append(annealing_temp)\n",
    "            tp.append(tp[-1] + annealing_dur)\n",
    "            Tp.append(annealing_temp)\n",
    "\n",
    "            # extension\n",
    "            tp.append(tp[-1] + (extension_temp - annealing_temp) / heat_rate)\n",
    "            Tp.append(extension_temp)\n",
    "            tp.append(tp[-1] + extension_dur)\n",
    "            Tp.append(extension_temp)\n",
    "\n",
    "        tp.append(tp[-1] - (Ta - Tp[-1]) / cool_rate)\n",
    "        Tp.append(Ta)\n",
    "        fig, ax = plt.subplots(1, 1, figsize=(0.75 + max(tp)/600, 4))\n",
    "        ax.plot(tp, Tp)\n",
    "        ax.set_xlabel('time / sec')\n",
    "        ax.set_ylabel('temperature / deg C')\n",
    "        ax.set_title('PCR Temperature Program')\n",
    "        ax.plot(tp, Tp, 'r.', ms=3)\n",
    "        ax.grid(True)\n",
    "        df = pd.DataFrame()\n",
    "        df['tp'] = tp\n",
    "        df['Tp'] = Tp\n",
    "        df.to_csv(filename_text)\n",
    "\n",
    "    display(filename_text)\n",
    "    display(widgets.HBox([heat_rate_label, heat_rate]))\n",
    "    display(widgets.HBox([cool_rate_label, cool_rate]))\n",
    "    display(widgets.HBox([pcr_cycles_label, pcr_cycles]))\n",
    "    display(denaturation)\n",
    "    display(annealing)\n",
    "    display(extension)\n",
    "\n",
    "    out = widgets.interactive_output(create_setpoint_trajectory, {\n",
    "        'filename_text': filename_text,\n",
    "        'heat_rate': heat_rate, \n",
    "        'cool_rate': cool_rate,\n",
    "        'pcr_cycles': pcr_cycles,\n",
    "        'denaturation_temp': denaturation_temp,\n",
    "        'denaturation_dur': denaturation_dur,\n",
    "        'annealing_temp': annealing_temp,\n",
    "        'annealing_dur': annealing_dur,\n",
    "        'extension_temp': extension_temp,\n",
    "        'extension_dur': extension_dur,\n",
    "        })\n",
    "\n",
    "    display(out)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## PCR Thermal Profile for Heater 1"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {
    "colab": {
     "base_uri": "https://localhost:8080/",
     "height": 572,
     "referenced_widgets": [
      "4dbf1db2dd5d42af9b6d1c7b8e4fdaec",
      "7095263b1ace4d0a93fdbf752c45d6d8",
      "da5eb9491f66409688973c010ac0c864",
      "49302012c42845e786c936778c222f16",
      "1785a94217be499ba8539e7fc52863bc",
      "e9886b9fd3df43489c7e404cecaf42c8",
      "421266dbc6544fce8f11e465a5a4dbf5",
      "dedb204e564f4474837d6e174f94d719",
      "a2fdb96d45eb4965b913b17f1c8163ae",
      "167dbc34ef724a8ea74a32f0c528b98e",
      "86a21c91e2534f39becc26de183beaf6",
      "eacb9c40192444a5be734b67d3c48aa0",
      "3b034f6c70fd42fd908b19c0965ae063",
      "cba45f6e566f416280afc4fcdc808692",
      "a128500e037e45318108eb2686cd2d33",
      "30fee7f75b5e4ae6a9aca37bebfc7d83",
      "ac3fa9be59b34b28851710ed2c2e8ba5",
      "2b96e4470e894aef88f66984a526ee11",
      "465bf6171a2746dface91d7f361765b7",
      "9b1941f56e734a91a7ae2110084ec0ed",
      "4c5107f7d08f464ea8d824016afd667c",
      "2a91037ecc2c46399b85aacc880f1177",
      "3de41a572e5e42ad86ec0e62139eeb80",
      "f8607f3d257c44b997c5e54a6cd2e08a",
      "130d454037b645db901e3bddf8f16877",
      "109e276b736845ed9b6d16495dd2b4f0",
      "c78c40592afb491a99a5dfa4b3f5c8f1",
      "7d146eb78c5b4747956e25d04b09affa",
      "24880eeeaa3c476aaa5a554744a5084c",
      "e57ae2c434c44516bbbff1b4f7447b39",
      "4371d513ff684bd7938b9c31707436d7",
      "dad066feb811486bb29c512755b7302e",
      "43637f0013664f1290f0bf374b3f5b0f",
      "4670f9bd8c8c48fc8a5cf25e073ec900",
      "1df39bad8ff34edf91a7fe438ebc48e8",
      "fd17a1e6b4254d49aa2dbb7a49fe77b5",
      "ef971f8422594f069b9792976b89a25f",
      "49a8de4b228449cbb30b153e04171739",
      "f4818089299346f19505570c38e100f4",
      "00ec856d54e74129afc3b144c42a2509",
      "3181c5b32d7a47dda3973e0269135ef7",
      "6bf8ee8a738841b7af8120b2a7a9cbc7",
      "e6c94812e41d41ebbb3fc25248b038e5",
      "3e4b4e50a7134173bc8733cae4bf4166",
      "c5be64294277465080c440372056c928",
      "4635efe6af9d4fa681bd627729de832b",
      "2ea185456c2b4ed18f0861c6fb86b040"
     ]
    },
    "colab_type": "code",
    "executionInfo": {
     "elapsed": 1119,
     "status": "ok",
     "timestamp": 1586830181550,
     "user": {
      "displayName": "Jeffrey Kantor",
      "photoUrl": "https://lh3.googleusercontent.com/a-/AOh14Gg_n8V7bVINy02QRuRgOoMo11Ri7NKU3OUKdC1bkQ=s64",
      "userId": "09038942003589296665"
     },
     "user_tz": 240
    },
    "id": "9lPvnCz9kuWC",
    "outputId": "269b4301-8edc-4ea7-9500-68d5426ddc22"
   },
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "6607ae57ab5c4b0893e1df1e27805c28",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "Text(value='pcr/pcr1.csv', description='Filename')"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "311bf79c4e744f4798c81d4cbab0caa8",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Heat Rate [deg C/sec]', layout=Layout(width='140px')), FloatSlider(value=0.5, max=…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "a2993667a01241ffb89ed5acfcb6aede",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Cool Rate [deg C/sec]', layout=Layout(width='140px')), FloatSlider(value=0.5, max=…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "2ca4bb1c004c465e9954f8dbd31370fd",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='PCR Cycles', layout=Layout(width='140px')), IntSlider(value=12, max=30, min=1)))"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "cfd0f25665db482cac34c86cd86aba92",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Denaturation', layout=Layout(width='80px')), FloatSlider(value=94.0, description='…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "8840816ce29f4bd3ad685a754b96139f",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Annealing', layout=Layout(width='80px')), FloatSlider(value=64.0, description='Tem…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "27cd5c472fe34ab3b21fdaf69852d2b7",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Extension', layout=Layout(width='80px')), FloatSlider(value=70.0, description='Tem…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "36272ef5f0ec442e9998a7cfe65d0df9",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "Output()"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "PCR_thermal_cycle('pcr/pcr1.csv')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## PCR Thermal Profile for Heater 2"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {
    "colab": {
     "base_uri": "https://localhost:8080/",
     "height": 572,
     "referenced_widgets": [
      "21652469b2fc469d89276764df3bec9c",
      "f0091324a47f4dceb9e1a888d33b6e04",
      "19b9ccc1bffe42a2bf918e57ecf039e0",
      "5c04378beb844f749c6d83de11896b26",
      "14207805d8bf49228e91ea0ddd9756dd",
      "4599e4df7a57463c99e654e4747a720b",
      "7fe78215138b46cab2afb6665a761cdc",
      "bd98243273464c2da5b8fdf6066f687a",
      "5792fd15020f40edbd6da1f63c58c503",
      "d1663d93e42341278a6be526dd532b76",
      "6f4c32ce47774344b6d8ffa18a78166f",
      "9122619ce93f462bbb52a7ebe0d954af",
      "617e31085bcf4dd8aee150157e5ea75d",
      "ba37b15e7ed348ea924a58588fac353f",
      "4036274cc47e4ffea6fd0e739cae6235",
      "96a257dcb8e1473db151a6824801a873",
      "e0aea54962294e45af5790c87034b0fd",
      "9e2a87d72fe64710bc0f6a12880e7d33",
      "6db2113a82c04eaa92f1bd7da8d8bead",
      "28758dce32d143c89e09b5e9019cdff8",
      "222263180d8e484faec3c006a2bcc0aa",
      "cf9a26346571456881e12f4a442a46e5",
      "6656167384d344418f402f22552fd779",
      "e973848151494e7da617039ed941960d",
      "9b6b9577e6124b6fa8ebc059f2569e42",
      "d9db3b4edeb949419bd2ae2f1c6cb170",
      "7aa969143d8e46919d8a2924791515fa",
      "d430b208deb54f48b43d738050ffa9cd",
      "fd41b4626e0d47c1aee3a6409dc4df63",
      "4c3f1a3c854844e3b92a315e8d42e16e",
      "74c3361410ec4a69a4ecbae6f9c2dc78",
      "5aa68cb08a404ccab676e598aaeb8b5a",
      "a9af4ee00c164def88cd3968d909b942",
      "612ba6f12f7142efa0d701fc896a7f76",
      "bb9f13877360488fa0dbd5abfb7d8877",
      "64dab15d88994416be40c6e026499973",
      "a2a22672f2694665897c76066fd6ce03",
      "6da787883c9b4f8aa58b843594701502",
      "187874bc732d4289aaa3aa7875b30542",
      "b999b85cb9f34c87aa51e368ff7b1875",
      "b06b974c9d9e4dca994e5b1e5c0b7341",
      "444239cc20c6471ca5a215e7b9a228d2",
      "52017046c2444392849039769bac0956",
      "7ffc999f18a044abb72fd70ce39e9b96",
      "882c7be927014bd5b06b261009111a09",
      "bdde8044fd834246bc958dce5c488c19",
      "c5c2bf48c0bc45468b10dd906861729c"
     ]
    },
    "colab_type": "code",
    "executionInfo": {
     "elapsed": 1068,
     "status": "ok",
     "timestamp": 1586830200937,
     "user": {
      "displayName": "Jeffrey Kantor",
      "photoUrl": "https://lh3.googleusercontent.com/a-/AOh14Gg_n8V7bVINy02QRuRgOoMo11Ri7NKU3OUKdC1bkQ=s64",
      "userId": "09038942003589296665"
     },
     "user_tz": 240
    },
    "id": "cny16gdg6G_i",
    "outputId": "2804c9e7-31f8-4bd3-879c-1556d11e6f34"
   },
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "02f75b384d2c418da89885bed6049996",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "Text(value='pcr/pcr2.csv', description='Filename')"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "3d7960fb877049feb9b65fd6f3c57509",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Heat Rate [deg C/sec]', layout=Layout(width='140px')), FloatSlider(value=0.5, max=…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "08c9fd6ef79c4a358ee5ab8c790ef427",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Cool Rate [deg C/sec]', layout=Layout(width='140px')), FloatSlider(value=0.5, max=…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "65090efd519042db84c720a457158928",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='PCR Cycles', layout=Layout(width='140px')), IntSlider(value=12, max=30, min=1)))"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "8372c8e5ac9d4c56b95b15dc4fdb4467",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Denaturation', layout=Layout(width='80px')), FloatSlider(value=94.0, description='…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "998e178188264d598435f847627bf4e2",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Annealing', layout=Layout(width='80px')), FloatSlider(value=64.0, description='Tem…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "a6085be9976c4d48a5f30e6307ca5f30",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "HBox(children=(Label(value='Extension', layout=Layout(width='80px')), FloatSlider(value=70.0, description='Tem…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "bd3db15bb30e421fb888af28b7533076",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "Output()"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "PCR_thermal_cycle('pcr/pcr2.csv')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Parallel Operation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {
    "colab": {
     "base_uri": "https://localhost:8080/",
     "height": 403,
     "referenced_widgets": [
      "73549fc77c0d4766a716314e061951f6",
      "e5e3949463674e88a9f885d96b0cab81",
      "55084ff0c40a4f4fb238d41906ac3ae7",
      "135e724fef8f4b1187abc92edb57237f",
      "eb56b460a87f449eb0b8be05893b4a83",
      "a49bc44d69194be48ff627ed7a3b96a5",
      "75874a259768476f9a0abf30bd526d83",
      "09809328c28e45438ec55b70edefe371",
      "87fafc898f97480893ab87fa76562452",
      "90b5a1506c6a4315b71dcb33ae2282e1"
     ]
    },
    "colab_type": "code",
    "executionInfo": {
     "elapsed": 1790,
     "status": "ok",
     "timestamp": 1586830881198,
     "user": {
      "displayName": "Jeffrey Kantor",
      "photoUrl": "https://lh3.googleusercontent.com/a-/AOh14Gg_n8V7bVINy02QRuRgOoMo11Ri7NKU3OUKdC1bkQ=s64",
      "userId": "09038942003589296665"
     },
     "user_tz": 240
    },
    "id": "9TwKI7imKrp_",
    "outputId": "10645d6c-44ea-4327-b878-590119cbfbfa"
   },
   "outputs": [
    {
     "data": {
      "application/vnd.jupyter.widget-view+json": {
       "model_id": "1c43f8a592c14caaad8e11dc30e7c191",
       "version_major": 2,
       "version_minor": 0
      },
      "text/plain": [
       "interactive(children=(Combobox(value='pcr/pcr1.csv', description='file1', ensure_option=True, options=('pcr/pc…"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
    {
     "data": {
      "text/plain": [
       "<function __main__.get_data(file1, file2)>"
      ]
     },
     "execution_count": 4,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "import glob\n",
    "csv_files = glob.glob(\"pcr/*.csv\")\n",
    "\n",
    "def get_data(file1, file2):\n",
    "    fig, ax = plt.subplots(1,2, figsize=(15,5))\n",
    "    if file1:\n",
    "        df1 = pd.read_csv(file1)\n",
    "        ax[0].plot(df1['tp'], df1['Tp'], 'b')\n",
    "    if file2:\n",
    "        df2 = pd.read_csv(file2)\n",
    "        ax[0].plot(df2['tp'], df2['Tp'], 'r')\n",
    "    ax[0].grid(True)\n",
    "    if file1 and file2:\n",
    "        tmax = max(df1['tp'].max(), df2['tp'].max())\n",
    "        t = np.linspace(0, tmax, int(tmax+1))\n",
    "        u1 = np.interp(t, df1['tp'].to_numpy(), df1['Tp'].to_numpy())\n",
    "        u2 = np.interp(t, df2['tp'].to_numpy(), df2['Tp'].to_numpy())\n",
    "        ax[1].plot(u1, u2)\n",
    "        ax[1].axis('square')\n",
    "\n",
    "widgets.interact(get_data, \n",
    "    file1 = widgets.Combobox(value=\"pcr/pcr1.csv\", options=csv_files, ensure_option=True),\n",
    "    file2 =  widgets.Combobox(value=\"pcr/pcr2.csv\", options=csv_files, ensure_option=True)\n",
    ")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {
    "colab": {},
    "colab_type": "code",
    "id": "KW75ZpCsNtPG"
   },
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "colab": {
   "authorship_tag": "ABX9TyMfhJjSb/1CsAgioT8c8Nxz",
   "collapsed_sections": [],
   "name": "TCLab PCR UI Development.ipynb",
   "provenance": [],
   "toc_visible": true
  },
  "kernelspec": {
   "display_name": "Python 3",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.7.4"
  },
  "widgets": {
   "application/vnd.jupyter.widget-state+json": {
    "00ec856d54e74129afc3b144c42a2509": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "09809328c28e45438ec55b70edefe371": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "109e276b736845ed9b6d16495dd2b4f0": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_e57ae2c434c44516bbbff1b4f7447b39",
      "placeholder": "​",
      "style": "IPY_MODEL_24880eeeaa3c476aaa5a554744a5084c",
      "value": "Annealing"
     }
    },
    "130d454037b645db901e3bddf8f16877": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "135e724fef8f4b1187abc92edb57237f": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "ComboboxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "ComboboxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "ComboboxView",
      "continuous_update": true,
      "description": "file2",
      "description_tooltip": null,
      "disabled": false,
      "ensure_option": true,
      "layout": "IPY_MODEL_87fafc898f97480893ab87fa76562452",
      "options": [
       "data1.csv",
       "data.csv",
       "PCR_trajectory.csv",
       "data2.csv"
      ],
      "placeholder": "​",
      "style": "IPY_MODEL_09809328c28e45438ec55b70edefe371",
      "value": "data2.csv"
     }
    },
    "14207805d8bf49228e91ea0ddd9756dd": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "167dbc34ef724a8ea74a32f0c528b98e": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "IntSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "IntSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntSliderView",
      "continuous_update": true,
      "description": "PCR Cycles",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_eacb9c40192444a5be734b67d3c48aa0",
      "max": 30,
      "min": 1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "d",
      "step": 1,
      "style": "IPY_MODEL_86a21c91e2534f39becc26de183beaf6",
      "value": 6
     }
    },
    "1785a94217be499ba8539e7fc52863bc": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "187874bc732d4289aaa3aa7875b30542": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_882c7be927014bd5b06b261009111a09",
      "max": 120,
      "min": 10,
      "step": 1,
      "style": "IPY_MODEL_7ffc999f18a044abb72fd70ce39e9b96",
      "value": 20
     }
    },
    "19b9ccc1bffe42a2bf918e57ecf039e0": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "1df39bad8ff34edf91a7fe438ebc48e8": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_ef971f8422594f069b9792976b89a25f",
       "IPY_MODEL_49a8de4b228449cbb30b153e04171739",
       "IPY_MODEL_f4818089299346f19505570c38e100f4"
      ],
      "layout": "IPY_MODEL_fd17a1e6b4254d49aa2dbb7a49fe77b5"
     }
    },
    "21652469b2fc469d89276764df3bec9c": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "TextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "TextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "TextView",
      "continuous_update": true,
      "description": "Filename",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_19b9ccc1bffe42a2bf918e57ecf039e0",
      "placeholder": "​",
      "style": "IPY_MODEL_f0091324a47f4dceb9e1a888d33b6e04",
      "value": "data2.csv"
     }
    },
    "222263180d8e484faec3c006a2bcc0aa": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "24880eeeaa3c476aaa5a554744a5084c": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "28758dce32d143c89e09b5e9019cdff8": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "2a91037ecc2c46399b85aacc880f1177": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "2b96e4470e894aef88f66984a526ee11": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "2ea185456c2b4ed18f0861c6fb86b040": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "30fee7f75b5e4ae6a9aca37bebfc7d83": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_4c5107f7d08f464ea8d824016afd667c",
      "max": 98,
      "min": 90,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_9b1941f56e734a91a7ae2110084ec0ed",
      "value": 94
     }
    },
    "3181c5b32d7a47dda3973e0269135ef7": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "3b034f6c70fd42fd908b19c0965ae063": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_a128500e037e45318108eb2686cd2d33",
       "IPY_MODEL_30fee7f75b5e4ae6a9aca37bebfc7d83",
       "IPY_MODEL_ac3fa9be59b34b28851710ed2c2e8ba5"
      ],
      "layout": "IPY_MODEL_cba45f6e566f416280afc4fcdc808692"
     }
    },
    "3de41a572e5e42ad86ec0e62139eeb80": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "3e4b4e50a7134173bc8733cae4bf4166": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "4036274cc47e4ffea6fd0e739cae6235": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_6db2113a82c04eaa92f1bd7da8d8bead",
      "placeholder": "​",
      "style": "IPY_MODEL_9e2a87d72fe64710bc0f6a12880e7d33",
      "value": "Denaturation"
     }
    },
    "421266dbc6544fce8f11e465a5a4dbf5": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Cooling Rate",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_a2fdb96d45eb4965b913b17f1c8163ae",
      "max": 2,
      "min": 0.1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": ".2f",
      "step": 0.01,
      "style": "IPY_MODEL_dedb204e564f4474837d6e174f94d719",
      "value": 0.5
     }
    },
    "43637f0013664f1290f0bf374b3f5b0f": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "4371d513ff684bd7938b9c31707436d7": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "444239cc20c6471ca5a215e7b9a228d2": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "4599e4df7a57463c99e654e4747a720b": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "4635efe6af9d4fa681bd627729de832b": {
     "model_module": "@jupyter-widgets/output",
     "model_name": "OutputModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/output",
      "_model_module_version": "1.0.0",
      "_model_name": "OutputModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/output",
      "_view_module_version": "1.0.0",
      "_view_name": "OutputView",
      "layout": "IPY_MODEL_2ea185456c2b4ed18f0861c6fb86b040",
      "msg_id": "",
      "outputs": [
       {
        "image/png": "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\n",
        "metadata": {
         "needs_background": "light",
         "tags": []
        },
        "output_type": "display_data",
        "text/plain": "<Figure size 324.288x360 with 1 Axes>"
       }
      ]
     }
    },
    "465bf6171a2746dface91d7f361765b7": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "4670f9bd8c8c48fc8a5cf25e073ec900": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "49302012c42845e786c936778c222f16": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Heat Rate",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_e9886b9fd3df43489c7e404cecaf42c8",
      "max": 2,
      "min": 0.1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": ".2f",
      "step": 0.01,
      "style": "IPY_MODEL_1785a94217be499ba8539e7fc52863bc",
      "value": 0.5
     }
    },
    "49a8de4b228449cbb30b153e04171739": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_e6c94812e41d41ebbb3fc25248b038e5",
      "max": 72,
      "min": 68,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_6bf8ee8a738841b7af8120b2a7a9cbc7",
      "value": 70
     }
    },
    "4c3f1a3c854844e3b92a315e8d42e16e": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "4c5107f7d08f464ea8d824016afd667c": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "4dbf1db2dd5d42af9b6d1c7b8e4fdaec": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "TextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "TextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "TextView",
      "continuous_update": true,
      "description": "Filename",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_da5eb9491f66409688973c010ac0c864",
      "placeholder": "​",
      "style": "IPY_MODEL_7095263b1ace4d0a93fdbf752c45d6d8",
      "value": "data1.csv"
     }
    },
    "52017046c2444392849039769bac0956": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "55084ff0c40a4f4fb238d41906ac3ae7": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "ComboboxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "ComboboxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "ComboboxView",
      "continuous_update": true,
      "description": "file1",
      "description_tooltip": null,
      "disabled": false,
      "ensure_option": true,
      "layout": "IPY_MODEL_75874a259768476f9a0abf30bd526d83",
      "options": [
       "data1.csv",
       "data.csv",
       "PCR_trajectory.csv",
       "data2.csv"
      ],
      "placeholder": "​",
      "style": "IPY_MODEL_a49bc44d69194be48ff627ed7a3b96a5",
      "value": "data1.csv"
     }
    },
    "5792fd15020f40edbd6da1f63c58c503": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "5aa68cb08a404ccab676e598aaeb8b5a": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "5c04378beb844f749c6d83de11896b26": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Heat Rate",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_4599e4df7a57463c99e654e4747a720b",
      "max": 2,
      "min": 0.1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": ".2f",
      "step": 0.01,
      "style": "IPY_MODEL_14207805d8bf49228e91ea0ddd9756dd",
      "value": 0.5
     }
    },
    "612ba6f12f7142efa0d701fc896a7f76": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "617e31085bcf4dd8aee150157e5ea75d": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_4036274cc47e4ffea6fd0e739cae6235",
       "IPY_MODEL_96a257dcb8e1473db151a6824801a873",
       "IPY_MODEL_e0aea54962294e45af5790c87034b0fd"
      ],
      "layout": "IPY_MODEL_ba37b15e7ed348ea924a58588fac353f"
     }
    },
    "64dab15d88994416be40c6e026499973": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "6656167384d344418f402f22552fd779": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "6bf8ee8a738841b7af8120b2a7a9cbc7": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "6da787883c9b4f8aa58b843594701502": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_52017046c2444392849039769bac0956",
      "max": 72,
      "min": 68,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_444239cc20c6471ca5a215e7b9a228d2",
      "value": 70
     }
    },
    "6db2113a82c04eaa92f1bd7da8d8bead": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "6f4c32ce47774344b6d8ffa18a78166f": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "7095263b1ace4d0a93fdbf752c45d6d8": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "73549fc77c0d4766a716314e061951f6": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "VBoxModel",
     "state": {
      "_dom_classes": [
       "widget-interact"
      ],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "VBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "VBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_55084ff0c40a4f4fb238d41906ac3ae7",
       "IPY_MODEL_135e724fef8f4b1187abc92edb57237f",
       "IPY_MODEL_eb56b460a87f449eb0b8be05893b4a83"
      ],
      "layout": "IPY_MODEL_e5e3949463674e88a9f885d96b0cab81"
     }
    },
    "74c3361410ec4a69a4ecbae6f9c2dc78": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "75874a259768476f9a0abf30bd526d83": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "7aa969143d8e46919d8a2924791515fa": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_5aa68cb08a404ccab676e598aaeb8b5a",
      "max": 70,
      "min": 55,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_74c3361410ec4a69a4ecbae6f9c2dc78",
      "value": 64
     }
    },
    "7d146eb78c5b4747956e25d04b09affa": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_4670f9bd8c8c48fc8a5cf25e073ec900",
      "max": 120,
      "min": 20,
      "step": 1,
      "style": "IPY_MODEL_43637f0013664f1290f0bf374b3f5b0f",
      "value": 60
     }
    },
    "7fe78215138b46cab2afb6665a761cdc": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Cooling Rate",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_5792fd15020f40edbd6da1f63c58c503",
      "max": 2,
      "min": 0.1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": ".2f",
      "step": 0.01,
      "style": "IPY_MODEL_bd98243273464c2da5b8fdf6066f687a",
      "value": 0.5
     }
    },
    "7ffc999f18a044abb72fd70ce39e9b96": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "86a21c91e2534f39becc26de183beaf6": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "87fafc898f97480893ab87fa76562452": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "882c7be927014bd5b06b261009111a09": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "90b5a1506c6a4315b71dcb33ae2282e1": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "9122619ce93f462bbb52a7ebe0d954af": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "96a257dcb8e1473db151a6824801a873": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_222263180d8e484faec3c006a2bcc0aa",
      "max": 98,
      "min": 90,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_28758dce32d143c89e09b5e9019cdff8",
      "value": 94
     }
    },
    "9b1941f56e734a91a7ae2110084ec0ed": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "9b6b9577e6124b6fa8ebc059f2569e42": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "9e2a87d72fe64710bc0f6a12880e7d33": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "a128500e037e45318108eb2686cd2d33": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_465bf6171a2746dface91d7f361765b7",
      "placeholder": "​",
      "style": "IPY_MODEL_2b96e4470e894aef88f66984a526ee11",
      "value": "Denaturation"
     }
    },
    "a2a22672f2694665897c76066fd6ce03": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_b06b974c9d9e4dca994e5b1e5c0b7341",
      "placeholder": "​",
      "style": "IPY_MODEL_b999b85cb9f34c87aa51e368ff7b1875",
      "value": "Extension"
     }
    },
    "a2fdb96d45eb4965b913b17f1c8163ae": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "a49bc44d69194be48ff627ed7a3b96a5": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "a9af4ee00c164def88cd3968d909b942": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "ac3fa9be59b34b28851710ed2c2e8ba5": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_3de41a572e5e42ad86ec0e62139eeb80",
      "max": 120,
      "min": 30,
      "step": 1,
      "style": "IPY_MODEL_2a91037ecc2c46399b85aacc880f1177",
      "value": 60
     }
    },
    "b06b974c9d9e4dca994e5b1e5c0b7341": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "b999b85cb9f34c87aa51e368ff7b1875": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "ba37b15e7ed348ea924a58588fac353f": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "bb9f13877360488fa0dbd5abfb7d8877": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_a2a22672f2694665897c76066fd6ce03",
       "IPY_MODEL_6da787883c9b4f8aa58b843594701502",
       "IPY_MODEL_187874bc732d4289aaa3aa7875b30542"
      ],
      "layout": "IPY_MODEL_64dab15d88994416be40c6e026499973"
     }
    },
    "bd98243273464c2da5b8fdf6066f687a": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "bdde8044fd834246bc958dce5c488c19": {
     "model_module": "@jupyter-widgets/output",
     "model_name": "OutputModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/output",
      "_model_module_version": "1.0.0",
      "_model_name": "OutputModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/output",
      "_view_module_version": "1.0.0",
      "_view_name": "OutputView",
      "layout": "IPY_MODEL_c5c2bf48c0bc45468b10dd906861729c",
      "msg_id": "",
      "outputs": [
       {
        "image/png": "iVBORw0KGgoAAAANSUhEUgAAAN0AAAFNCAYAAACE1WrtAAAABHNCSVQICAgIfAhkiAAAAAlwSFlzAAALEgAACxIB0t1+/AAAADh0RVh0U29mdHdhcmUAbWF0cGxvdGxpYiB2ZXJzaW9uMy4yLjEsIGh0dHA6Ly9tYXRwbG90bGliLm9yZy+j8jraAAAgAElEQVR4nO2deZhjZZWH35NUJdVVqd4qZcs2NCCLDSPNpmxqA7KOijNuMIgijKOCiMOoLegAAqOtMgLqiOK+ggroIKIsTRcoCEhD080qW0MDDVSqt0p1dVJVOfPHvbcqHZLUTXK3JN/7PHkqdz91c8/9tt93jqgqBoMhOGJhG2AwtBvG6QyGgDFOZzAEjHE6gyFgjNMZDAFjnM5gCBjjdAZDwDSl04nIahEZFZGsiLwsIj8WkVTR9qNF5A4RGRaRQRG5XUTeaW87RUQm7GM3iciDIvL2Ctc5yd4va1+vULScDer/9RIRWSQizwd8zaq/V7vRlE5n8w5VTQH7AvsDXwAQkfcAvwF+CmwPzAPOA95RdOxf7WNnA98GrhaR2aUXUNVfqGrK3vdY4EVn2V4XKcTC199URDrqPLTs7+XRucvi9fm8opmdDgBVfQH4I7CXiAjwdeAiVf2+qm5U1YKq3q6qHylzbAH4GdAD7FrLdUVkWxG51i5JnxGRTxZtu0BEfiMiP7dL21UispuInCMir4jIGhE5qmj/ARH5sojca5e+/ycic4u2Hygid4nIBrtkXlRy7H+LyJ3AZmBnEfmwiDxqX/tpEfmovW+Pfa+2LSqxt7VLnouLzrlVaWiXVItFZCUwIiId1WyqRvHvZZ9bReQMEXkCeMJe9xEReVJE1onI9SKybZEtR4nI4yKyUUS+bddi/s3edoqI3Ckil4rIEHCBiOwiIreJyJCIZETkF8UvWPt/+4yIrBSRERH5gYjME5E/2vfvVhGZ4+Z/c42qNt0HWA28zf6+A/AwcBGwB6DATlWOPQX4i/09DpwB5IHXTHPNRcDz9vcYsByrBE0AOwNPA0fb2y8AtgBHAx1Ype4zwOeBTuAjwDNF5x4AXsB6EHuAa4Gf29u2A4aA4+zrHmkv9xcd+xywp32tTuCfgF0AAd6K5Yz7lv4fRdf/MXBxuf+16H6vsO/1jOlscvt72csK3ALMtc99OJDBKhGTwDeBO+x908Am4F/s//UsYAz4t6Lfdhw4094+A3idbV8S6AfuAC4rse1urBrRdsArwP3APkAXcBtwvqfPb9gO1IDTZYENwLNYVcQZwCH2j9g1jdON28eOAaPA+1xcc/JBBN4EPFey/RzgR0VOd0vRtnfY9sbt5V7bztlFjrOkaP8FWC+COLAY+FnJtW4CPlR07IXT2P474KwGne7UouWqNrn9vYqc7vCifX8AfLVoOWX/TvOBD2I1DZxtAqxha6d7rpwNRce8C3igxLaTipavBa4oWj4T+J2Xz28k67wueZeq3lq8wq5SAGyDVbJU4m5VPdRuzP8AeDPw6xquvSNWFW1D0bo48Oei5ZeLvo8CGVWdKFoG64FyzrGmaP9nsUqstH2t94pIcZu0E1hWtFx8LCJyLHA+sBtWSdQNrHL1n1Wm+BpubCrlVb9XhXNvi1XSAKCqWft33c7etqZom5bpFCq9F/OAy7F+416s+7G+5JjS36p02dP2e9O36Up4HOumv9vNzqqaBT4OnCwi+9RwnTVY1cPZRZ9eVT2udpMn2aHo+z9gvd0z9rV+VnKtHlVdUvyvOF9EJIn1tr4EmKeqs4EbsUqFrfYtYgTLMR1eW2af4uPc2FQLxed+Ecupgcl2aB9W9XstVueYs02Kl8ucC+BL9rp/VNWZwAeYuheh0FJOp1Z94Gzgv+zOhJkiEhORQ0XkygrHrAO+j9U+c8u9wLDduTBDROIispeIHNCA+R8QkQUi0g1cCFxjl4w/B94h1jBIXES67I6O0ofNIYHVfhkExu1S76ii7S8DfSIyq2jdCuA4EZkrIq8FPjWNrbXaVAtXAR8WkYX2C+RLwD2quhr4A/CPIvIusXomz6D8C6KYXqyq7UYR2Q74jAc2NkRLOR2Aql4DvB84Feut+TJwMfB/VQ67DOuhe4PLa0wAbwcWYlVjM1iOO6vacdPwM6y21UtYDfhP2tdaAxwPnIvlSGuwHpyyv52qDtvH/hqrGvWvwPVF2x/DerCftnset7Wv/SBW++Zm4FfVDK3Vplqwq6D/hVVar8XqEDrB3pYB3gt8FavjZgFwH5CrcsovYnXKbMRy2usatbFRxG4sGkJERAaweiu/H7YtzYRYY5LPY3WEVGtPRoqWK+kMrY1dpZ1tVz3PxWqf3R2yWTVhnM7QbBwEPIVVpX8HVq/oaPVDooWpXhoMAWNKOoMhYIzTGQwB0xSKlHQ6rfPnzy+7bWRkhJ6enmANcklUbYuqXRBd24rtWr58eUZV++s+mZeaMr8+++23n1Zi2bJlFbeFTVRti6pdqtG1rdgu4D5t4Hk21UuDIWCM0xkMAWOczmAIGON0BkPAGKczGALGOJ3BEDDG6QyGgDFOZzAEjHE6gyFgmkIGFjT5m25m+LPn8uC/n83LBxxacb/tlt/FIT+9nPjFF8MRRwRm35Y/3Ux28bmsnMa+7e+/i0N+8g1iF18UqH0jf7yJ0cWfZ+VHq9u3w/1/5eCfXk7somDtCxvjdGXILj6XvpXLmfmlizj15Esq7nfNz75I/MXH4LzzAn1osp89l/Qqd/bFQrJv3kP3u7DvglDsCxvjdGW4+5SzeM3XvsQ2l3+Vu48s/zCMFwp8dvUHuGTVtWx74YWB2nf7B85kx8uXsOP/XsLdh5W3b3jLGOev/gCXPnwd8wK275YTzmDBdy5h5//9H+5+62Fl93lp0xa+uvoDfOOR35IO2L6wMU5Xhgd3358fnfJ1Hn/3MVhR3srz8OsP4IoTjueiI/YK0Dp4YLd9ueijl7PiXUdV3GfezCR/22UffnzKu1l8xB4BWgf37bIP3/nEt/jLOw+vuM/s7k7umr+QX330/Zxx2OsCtC58TEdKGTLDefpSiaoOB5BOJchkqwWi8ofMcJ50Kll1HxGhrydJZjgE+7LT29fVGSeV7GAwBPvCxjhdGYZGctM+NADpVJKhbD4Ai7bGsi8x7X7p3pBeClm39y/B0Ejw9y9sjNOVwXpo3DzUyZAe6ulLErBfCiE81Jlsnv5eF/cvFU5JHDbG6crgpvoG0J9KMhhK9dJ9SRz0Qz1RUNbVUFMI46UVNsbpSlBVq/rW6656NLxlnC1jE9Pu6xVbxiYYzo3T78q+JJls3sk+EwjrN+cpKO6cLqTqb9gYpyth4+gYYxPq+k0NBFqFcx5SV9XfVIL8RIFNW8b9NmuSKfvc3b/1m8cYmyj4bVakME5XQi0PdZ/9YAVZhcvYHTe1vBSCLE0yw5Z9fTXcv3Vt1pnid37qs0TkIRF5WEQ+Za+bKyK3iMgT9l9vU8s2yOBwLQ+19WAF+1Bb1+qrxekCfSm4L+n67fvXbsMGvjmdiOyFleb3jcDewNtF5HXA54ClqrorsNRejgy1Vo+KjwmCmqqXvc5LIfjqb39E718U8LOkez1WXrHNqjoO3I6VK/p44Cf2Pj/BSkcbGWp5qJ3OjDAe6qi+FAazORLxGDNnTC92mrLPVC+94iHgzSLSZyc6PA4r2+g8VV1r7/MSVoL1yJDJ5ojHhDnd0ztdGKqKTDZPb7KDrs74tPvO6U4Qk+DbdG7UPMBkD3G7lXS+aS9V9VER+QpWksERrGyfEyX7qIiU7c8WkX8H/h1g3rx5DAwMlL1ONputuK0eVj2RI9UJd9xxu6v9e+ITPPL0GgYGBn23DeCRp7fQHS+4Pm+qU1j599UMJNZOrvPDLoe/P7eFpKqr86sqiRg88OiTDOga321rBE/taiRSbS0frDS2p2PlBd/GXrcN8Ph0xwYZ4fnUH92rx1x2h+v93/3tO/X9372r7DY/ohW/7zt36XuuuNP1/kdferue9uO/bbXOzyjKx11+h57yw3tc73/IkqV61lX3Ty6bCM8NIiKvsf/+A1Z77pdYqXg/ZO/yIaqnJQ4ctxIwB2cAOiiGRtypZRz6A5aqDbmUqDkEff+igN/jdNeKyCPA74EzVHUDsAQ4UkSeAN5mL0eGTDbvqufNId2bYCjg3svaH+pg7NMa1DwO7SgF83U+naq+ucy6ISCS04RV1Xqoa3xoHFVFZ9zfd9jYRIENm8dqdDpLaqWqrjo3GqEWNY9Df2+CFWs2+GhV9DCKlCKyuXFy44Waq5cQjKrCmUaUdqHgd0inkmwZK7A5778+tJbhFod0Ksm6kRwThfbJCGycrohaJFYOzr5BDBvUMkbnEORYnaPmqal6nkpSUEso3S4Ypyuivoc6OCnYYB329QVon3MNNxI1hyDtiwrG6YqY0jXWXr0MogfOsa/WkgSmSiE/qbd6CVNC6XbAOF0RtegGHYJUVWTqaNP1B2qfezWPQzvqL43TFTGYzSMCc3vcPzQ9iThdnbFAlPyZbI4ZnXG6E+47nZ3/JRCnG84ztydBLOa+l7TfOF17k8nmmNOdoKOGrn8RCWysyRrOcP9CAOiMx5jT3RmcfTXUEgBmzuggEY+FEvYiLIzTFWHFHqntoYbgVBX1PNTgxEoJyr7a7p+I0JdKmDZdu9LQQx1Q9S3S9tWo5nFoN1WKcboi3Ia2K6U/oAA7db8UAtBfqiqDNap5HMIK2hsWxumKaKSkWzeS91VVMVFQ1m3OT4Y4qAXrofa3+pbNjZOvUc3jEFbQ3rAwTmezOT/O5vxEzR0VEIyqYt1IHlXqLEmSZHP+hgqsR83jkO5NMjSSCzRUYJgYp7MZauShCaDbux61jEN/yn+pWiP2pVNJxiaUjaNjXpsVSYzT2QzWMTDuMCkF87EHrqGHutf/sTpnnLI+p2svKZhxOpuGHpoAVB/1SKwcJoPi+thuasS+qZK4Pdp1xulsnDZJLbpLh3RPAE7nxOOso03XF0D1tx41j0MQ9kUJ43Q2Uwr52h+aIFQVmWyOREeM3mTt8477ApCC1aPmcTDVyzYlk80xs6uDZMf0oe1KCUJVMZjN0Z9K1jX7u6szTm9Xh6/DBvWqecAKFRiPiXG6dqPWMA2l+K2qsAbu63uowf+0XvWOcQLEYsLcnvaRghmns6lXYuXgt6rCbU66Svidq65eNY9DO0nBjNPZZOzqW734X9Ll6mpvOvidC66Rkg7aSwpmnM5msA6FfDHpXkvKVPBBClYoaM3xLkvxcyZEI2oeh/42in9pnA47u+mW8YYf6vGCP6qKjaNjTBRqC21XSjqVZOPoGPlx7xMwNqLmcUj3Wm3OdpCCGadjKpNqYx0pCftc3leRJgeeG+zoAX/sa0TN45BOJciPF9gSXCbp0DBOB5MRmht5U/upqhhsQO3h4KdUrRE1j4Nz7MacKenagkYkTA5+SsGctk5DJUkA9jXSpnOcblPeOF1DiMh/2KmPHxKRq0SkS0R2EpF7RORJEfmViNT/S3lEpoaUx5Xwc6aBFyXJZEnsi9PZap4eU9K5wc/0x9sBnwT2V9W9gDhwAvAV4FJVfR2wHjjNLxvcUk8Q11Jmz+j0TVWRyeboiAmzZnTWfQ4/g7o6ap5ER/2Pk1PLMCVd43QAM0SkA+gG1gKHA9fY2yOR/jiTzdGTiDMjUbsEzMFPVYUzRldLaLtSuhMddCfivsw0aFTNA5ZQWgQ2tUFJ52cm1hdE5BLgOWAUKyPrcmCDWjnIAZ4Htit3fJCZWB95ags9He6zm1aiizEee/ZFBgbWeWYbwOPPbqELd9lNq9ETL/DwU8+xzy7jnmY7ffL5UTqh4XOmOiAzkm/5TKy+OZ2IzAGOB3YCNgC/AY5xe7yqXglcCbD//vvrokWLyu43MDBApW1u+e7f72aHZIFFiw5u6Dzzn7qHTaNjLFp0qGe2AXz9ob8wf06CRYve2NB5dnjkTuKJOKnUFk/scrjwvgFev81MFi3at6HzbPPA7YwWRj21zSu8+i3B3+rl24BnVHVQVceA64BDgNl2dRNge+AFH21wRT3xGsvhl6qiUd2lg1/xLxtV8zikU0nTpmuQ54ADRaRbrPkoRwCPAMuA99j7RCL9caO6QQc/VBVWosp8Q93xDn6E4vNCzeOQTiVN72UjqOo9WB0m9wOr7GtdCSwGzhaRJ4E+4Ad+2eCGsYkC62vMbloJR1UxnBuffmeXbNoyTn6i0NAYnUM6lWTdZm9DBXqh5nFol5LO7/TH5wPnl6x+GmisceIh6zx+aMCqDs7sqr97vxhHLdPIDAOH/lQCVRge89DpPBhucUj3JshNWALqWpKkNBttr0gZnMz55k2bBKbe/l7QSDzJUiZVHx5W4bxQ8zgEEUApCrS90zUS2q6U4pLOKzy1r9d7qZUXah4HP1UzUaLtnc6LaSkOfsSX9OOl4GVnxeQMA4+r561M2zudF9NmHOZ2W6qKQQ+rR5nhHLE6Q9uVMiW1avhUk2SyOVLJDro661fzOEy9tEz1sqXJZHN0dcboaUAC5tARjzG329uwA4NZK7tpvAEJmEMq2UGyI+ZpSZfJ5j3p5IEpwXSrh20wTmcH1KkntF05rFB83lYvvahawlTWWG/bdN7Zl+iI0d1hnK7lscTE3jw04H2AIi+dDqwqpte9l170XDrMTLZ+/Mu2d7rB4ZwnwwUOXgcA8vqhTqeSbPSypPP4pTArIS0f/7Ltna7ReI2leF7SNRiPs5R0KsmwR07npZrHwZR0Lc5EQVk34nH1rTfB5vwEm/ONS8FGcuOMjk140rPqkO5NsCmvnoQK9FLN4zAzIWacrpVZvzlPQb1RUzhMjTU1XkXycozOwckau8GDUIFeqnkcZiWF4S3+Zo0Nm7Z2Oi/H6By8VFV4KbFy8DKWix8vhZkJqxfZSyld1Ghvp/NQwuTg7UPto30eDGt4qeZxmJW0nK6VVSnt7XR+VN9sVYUXot2MhxIrh37bPk9LYo/bdOBPUNyoYJyOxuJJluKlqsIpib2QgDlMlcTevBS8UvM4OE7XysMGbe50eRLxGDNneDd3K9ERY9aMTs/aTLO7O+msI7tpJWbN6CQu3lV/vVTzwFT1spV7MNvc6azQdl4+NOBd2ievB57BkoLNTIgnbSav1TwAibiQSna09Fhd2zud1w81WInrvRoy8LLn0sGrAWiv1TwOfalES880aHun80ohX0y/R6oUr9UyDjMT4lGbzh/7/M4aGzbt7XQeS6wc0qmEN72DHir4i7GcrjH7/FDzOLR6Vta2dTpVZci3hybJ8JZx8hP1S622jE0wnBv3dLjAYVZSGMrmGwoV6Ieax6HV849XdDoROUBEji2z/jgR2c9fs/xn4+gYYxPqz0NjO0ojwmI/1CgOMxNCfqLAptH69aF+jNE5pFNJ1m8eY2zC+6yxUaBaSfcVrOCwpTwMfM0fc4LDj4Fnh8lYJA05nfdqD4eZjuqjgQFoP9Q8Do4jr2tRKVg1p+tV1WdLV9rr0v6ZFAyDfj40TiySBiaLepGTrhKzEo1LrfxQ8zg4PaKDLdqZUs3p5lTZ1u21IUHj50PjRUnnyKD8qL5NlnQN9GD6oeZx8DPBZhSo5nS3ish/S9HIsVhcCNw23YlFZHcRWVH02SQinxKRuSJyi4g8Yf+t5ty+4WebyamyDjdS0tkO0eehBMxhsqRr4KH2Q83j0OpBZ6s53X8COwNPisi1InIt8ASwG3D2dCdW1cdVdaGqLgT2AzYDvwU+ByxV1V2BpfZy4GSyOeIxYU639w91V2ecVLKjoZJucDhHb5c3oe1KSSUg1qAUzC81D/ibHz0KVHxNqeoIcKKI7Azsaa9+WFWfruM6RwBPqeqzInI8sMhe/xNgACupSKBkhq3Qdo1kN62GFQCotodGVcmNWz12ltrD+6obQEyEuT21d8sXCkre7lF8xacxRICeRJyuzlhD9gG+vLC8YNpxOlV9WlV/b3/qcTiwco1fZX+fp6pr7e8vAfPqPGdD+DVG51BPqLuvffbbPDR/L049eQnrf/9HrrjiTFi61Cf7EpOdSW65+OxvTdo3fvMtXPqN032xzwkVWGub8/NnXj5p36knL+GFPff17f41gniZS63sBUQSwIvAnqr6sohsUNXZRdvXq+qr2nUl6Y/3u/rqq8ueP5vNkkqlarbrwr+O0t0hfPqArpqPdcM3H9jCC8PjLHmLe9tmn/xxFj7/GKt3WQDA/KceYeOee/LAt77lqW3ZbJYrHo0zOg7nHTTD1TGqyqyTT2ffF/y1z/k9L/zrKDM64DMHuLNvvKDMPvl09n/Rsm9DrsDC5x/zzL7i5+ywww5brqr7130yVfX1g5UC+eai5ceBbezv2wCPT3eO/fbbTyuxbNmyituqcfCXl+p/XP1AXce64dzrVuqeX7jB9f7jEwU96YSL9fkF+6jeeqv1Ofhg66/HLFu2TM+66n49ZMlS18cMbxnTE99/sa7d01/7nN/ztB/fq0dfervr49ZuGNUT33+xvvKP+6reeqsu+fS39JGd9vLMvuLnDLhPG/CJabueRGRumdXDaqU0dsOJTFUtAa7HysC6hJAysaqqb2Jnh3QqSXbMClPnZj7cupE8f9lxIUs/eRIfPGi+tfKII3y1L2NnjXXTGZIZznHX/IXc+ZkP8e79tg/EvhVrNrreP5O17Lv/v07j6D1fy+C6NKfN3YO7fLSxXtxoL+8HBoG/Y/VeDgKrReT+6eRgItIDHImVb9xhCXCkiDyBlZd8ST2GN0I2N05uvOBvm65GVYXTaeDMPPebdG+SLWMFRvLuom75KfsqRzqVZN1IznXW2MGSISCnTag+N5/qwY3T3QIcp6ppVe0DjgVuAE4Hvl3tQFUdUdU+Vd1YtG5IVY9Q1V1V9W2quq6Rf6Ae/JRYOdSqqvBz3LActQYoCt6+BAW1hNVuKFXwpFMJS1+6xbtU1F7hxukOVNWbnAVVvRk4SFXvBoJ57XlMEG/tWlUVwZckteXSc9J/+TWMUUqtY3WlL9Ioq1rcON1aEVksIjvan88CL4tIHGhKGfjUW9HfNh24l1r5KSAuR80vBfuezfFBIVOOWoP2ZrI5ZnTG6Ul2lBzfnE73r8D2wO+wFCU72OviwPv8M80//NQNOtT+ps5ZsqquYBLc9/fW+FLI5pjjcZCkatRTU3DCH0K0E0xO+wuragY4U0R61FKpFPOkP2b5y2A2j3iU3bQSPYk4iRgMua6+WfFQ/JBVlcP532t6qAMqhWHqhVivfU1dvRSRg0XkEeBRe3lvEanagRJ1rLd2gg4f39oiYgcAcluS5ANrzwF0xmPM6XYfKtCveCiVmDmjg0Q8VlP1vNi+Od2JhvWlfuHmqbsUOBoYAlDVB4G3+GmU31ixR/xvm9QSi2Qo4JIEnABA7quXQb4URMSOCuby/pXI+uKx+vSlQeDqVa+qa0pWNXVKlaCqSrOSUtOQQVDd8Q61xCIJ6kVVjFv7rCBJ+VeFA6xHXxoEbpxujYgcDKiIdIrIp7Grms3K0EgwVSW3oe4KBWUo4OobWJ09bh7q0fwEI/mJEEpidyXduhE7SFJJSdzfm4xkTgQ3Tvcx4AxgO+AFYKG93LT4FdqulJkJcaWq2Dg6xnhBA3+o+3rcBXUNore3HG6D9laKAhDVqGJuey9PCsCWQJh8a/cG0KZLyqSqoppDTUrAAq6+9fcmyeasBIzV5p5NSqwCuGfFpFNWSTWdPnRKQvfq6mUUE5FUdDoR+SZQ8RWtqp/0xSKfmXwrBqBxLA6LUM3pBkMqSdJFUrUd5lYOe+NnkKRqpFMJxiaUjaNjzK4yw7+SmiedSjI6NsFIbnxy0DwKVKte3gcsB7qAfbHEzk9gVS+DfeV5SJBv7ckAQNO8bSclTAH2DoL7sawgtKrl6HcpMKik5umL6FhdtXANPwEQkY8Dh6rquL38HeDPwZjnPUG+tWe6DAAUXkniTpUSVvXXsW9wOM/rXlN5v0pqnmJ96Y59Pb7ZWStuOlLmADOLllNUD88XaYJ8a0+m8p22JLGCJM2e0em7TcW4laplsjlmdnWQ7Ag25ojbkriSmqfYaaOEm4ruEuABEVkGCNbA+AV+GuUnQb61uzvgrc+t5C0fPocbP/EZXtzvkLL7jdx4E9f935XEjkj6OjG0lL6eBAevXsH+J53DjWdUtm/85lv55R++D2/uCNS+dMqyb8F7z+XG0z9d0b6O227jBzf/CN542Vb2ua2eBo2b3ssficgfgTfZqxar6kv+muUfQb61RYTP3f1LdnvmITZ97UucfvIlZfe75trvsPeLj8F55wX6UHd1xjn37qvY9dmH2VjNvt99l71CsG9Od4LP/fWX7PLcI6yvZt/vv8fry9hXq740KFx16dhOFnhYBT8IWs6023e+zvj55/H68y5g5WGHl90n/tbL0Iu+iFx4YWB2Oexx5aWRtS8WExZ877K67atVXxoU0elHDQi/ctJVIn7UkXDUkdVv9LFHW58Q6Ghx+2rRlwZF2+Wny2T9C+JqiB5RVKVUy0+3XEQuF5FjRMSf4JAhEIaw2BAebvWlQVKtpHsT1kzxRcDtInKjiJwlIrsFYpkP5MYn2LRlPPDxMEN4pFOJyCUiqTY4Po6VZ2AAQES2BY4BLhaRXYB7VPX0AGz0jKGQlB+G8Einkgy70JcGieuOFFV9Efgh8EMRiQEH+WaVT1QSxhpal+KwD9vPiUZaxbo6UlS1oKp3em2M3wQd5s4QPlEMUNRWvZdO17HpvWwfnIjZUQrF56vTichsEblGRB4TkUdF5KAwM7FOhd42TtcuRDHBpJtoYLuJyFIRechefoOIfMHl+S8H/qSqewB7Y4V5CC0TayaboycRZ0YiGg1qg//0RVAK5qak+x5wDjAGoKorsZI8VkVEZmGJo39gH5dX1Q1YqbN+Yu/2E+BdtZtdH0GHuTOET1dnnN6ujqZr03Wr6r0l69xkZdgJK8PPj0TkARH5vp3FJ7RMrEHFRjFEi/5UcrJpEQXcDBlk7HE5BRCR9wBrqx8yee59gTNV9R4RuZySqqSqqoiUDQlRkomVgYGBshfJZrMVt5Xy7Cub2aYn5nr/RqnFtiCJql3gj20dE6M8uWa0ofN6atd0WdBI/t0AABTESURBVCOBnYFbgc1Y0cD+Auzo4rjXAquLlt8M/IEQM7Eu/OJNeu51K13v3yj1Zon1m6japeqPbR//+X16+CWNndfLTKxVq5d2Zp7TVfVtQD+wh6oeqqrPunDml7BiZu5urzoCeISpTKwQYCbWsYkC6zePmeplG+IkiIwKVauXqjohIofa30uTh7jhTOAXIpIAngY+jNWO/LWInAY8S0CZf9aPGAlYu5JOJdk4OkZ+vECiI/yhaTdtugdE5HrgN8Ck46nqdZUPmdxnBbB/mU2BJ4KeCnNnJGDthlO7WTeS57Wzwp8w48bpurCShxRP21W2ziMeecIKI2cIn+KoYE3hdKr64SAM8RtHBtRnnK7tcJoUURk2mNbpRORHlIn0rKqn+mKRTwSdqN4QHdIR01+6qV7eUPS9C/hn4EV/zPGPTDZHsiNGKkLhtQ3BELWZBm6ql9cWL4vIVVhjdU2Fk0k0qPTChujQneigOxGPjP6ynv7TXYEqQa6jSdCh9wzRIkoBity06YbZuk33ErDYN4t8YnA4x/ZzZoRthiEk3CaYDAI31cveIAzxm0w2z8IdZodthiEk0qkkzw5tDtsMwN18uqVu1kUZKye1mWHQzkQpFF+1pJBdQDeQtmd3Oz0QM7FSITcN6zfbOanNcEHbkk4lWbc5z/hEgY54uFKwatXLjwKfArbFSg7pON0m4Fs+2+UpJiCRoT+VQBXWbc7zmt5wVSnV4l5eDlwuImeq6jcDtMlzhowErO2ZzHU3HGGnc1DVb4rIXsACrMFxZ/1P/TTMSzImIFHb49RyhkbCb9e5GTI4Hyu0+gLgRuBYrMHxpnG6wWFnhoFxunbFbVbXIHDTonwP1lScl2zx897ALF+t8phMNk9nXJg5w0jA2pXJmQYRSJvlxulGVbUAjIvITOAVYAd/zfKWTDZHX4+RgLUzqWQHiY5YJEo6N6/++0RkNlYovuVAFvirr1Z5jCUBM8MF7YyIRCYqWFWnE6to+LJa8Sq/IyJ/AmaqFfuyabBy0pn2XLtjScEiXr20Ix/dWLS8utkcDoJPeWyIJlYq5PBLOjdtuvtF5ADfLfEJVWXISMAMRGemgZs23ZuAk0TkWazARIJVCL7BV8s8YuPoGGMTaiRgBtK9CYZG8hQKSiwWXqeaG6c72ncrfMR5s/UbCVjbk04lmSgoG0bHmBtiYtBpq5d2YNkdgMPt75vdHBcVBoeNBMxgEZUBcjdTe87HmrR6jr2qE/i5n0Z5iZGAGRym9JcRdzqsQETvxA40q1bu8aaZ2DpkooAZbPqdAEUj4Q4buHG6vD104GTt6fHXJG/JZPPEBOZ0G6drd5qppPu1iHwXmC0iH8HK4PM9NycXkdUiskpEVojIffa6QNMfZ7I55vYkQ+2tMkSDWTM66YhJ9Nt0qnoJcA1wLbAbcF6N8+sOU9WFqurkNAg0/bGlRjGlnMGSgvVFIECRW9n9KmAGVhVzVYPXPB5rqhBY6Y8H8DG62GA2b4YLDJNEIW2WWM21KjuI/BtwHnAb1sD4W4ELVfWH055c5BlgPZazfldVrxSRDao6294uwHpnueTY4kys+1199dVlr5HNZkmlUhVt+M+Bzew2N8ZH3xD8bOHpbAuLqNoF/tv2P/dtIZtXzj+4tnCMxXYddthhy4tqbrUzXdZIrMypfUXLfbjInmrvu5399zXAg8BbgA0l+6yf7jz1ZmItFAq62+dv1ItveLjiPn4S1YynUbVL1X/bzv7VCj3oS7fWfFxgmVhthoDhouVhe50bh37B/vsK8FvgjcDLIrINgP33FTfnqodsbpzceMGM0RkmSfdaMw10mhqen7hxuieBe0TkAnug/G7g7yJytoicXekgEekRkV7nO3AU8BABpj82OekMpfSnkuQnCmzaMh6aDW46Up6yPw6Ok0w3QD4P+K09W7sD+KWq/klE/kZA6Y9N6D1DKcVSsFkzOkOxwU00sC/Wc2JVfRornkrp+iECSn/sDIKaIQODQ/EA+S794XQmuYkGtj/weWDH4v21Cab2TM4wMNVLg00UctW5qV7+AvgM1vhcwV9zvGUwm0eEUKdxGKJFFGYauHG6QVW93ndLfGAom2NOdyL02PWG6DCnO0FMpoTwYeDG6c4Xke9jSbYmLVXV63yzyiOMBMxQSjwmzO1JMhjx6uWHgT2w5tE51UsFmsDp8vT1mPacYWvCThDpxukOUNXdfbfEBzLZHG/Y3iSCNGxN2AGK3DR27hKRBb5b4gOZYVO9NLyaZijpDgRW2OLlHE0SDWw0P8FIfsKoUQyvwop/Ge023TG+W+EDZozOUIl0b5LRsQlGcuP0JINPKtOy0cAGJyVgpnpp2Jqwx+paNhrYlATMlHSGrZlMmxVVp6NJo4GZGQaGSjjPxGBI7bqWjQbmvMX6TO+loQQnfEeUS7py0cC+769ZjZPJ5pjZ1UGyIx62KYaI4Whxw3I6N1N7LhGRI4FNwO5Y0cBu8d2yBrESQZqqpeHVdMZjzOnujK7TichXVHUxcEuZdZElkzU56QyVSaeSDIWkv3RTvTyyzLpjvTbEazLZnBmjM1QkTClYRacTkY+LyCpgdxFZWfR5Boh8NtbMcM50ohgq0hdiKuRq1ctfAn8EvszWUZiHVXWdr1Y1SG58gk1bxk310lCRMFMhV3Q6Vd0IbARODM4cbxgyY3SGaejvTTKcG2fL2ARdncH2cEdezlUPGZMeyzANYapSWtvpzJCBoQJT+svg23Wt6XS2vMf0XhoqEWauupZ0ukGT8tgwDekQpWAt6XSZbI6eRJwZCSMBM5SnL0QpmO9OJyJxEXlARG6wl3cSkXtE5EkR+ZWIeN7bkcnmTXvOUJWuzji9XR0t26Y7C3i0aPkrwKWq+jqs3HWneX1BKzaKcTpDdfpTycmmSJD46nQisj3wT9izEuwkkIdjpVMGKxPru7y+rol3aXBDWAPkfpd0lwGfZSpeZh9WUkgnT9HzwHZeX3RoxIidDdOT7k0wNBJ89dK3qCwi8nbgFVVdLiKL6ji+OP0xAwMDZffLZrNbbZsoKOtH8mQzaxkYcJW70jdKbYsKUbULgrUttzHH2vXjrq7nqV2NpHGt9sHSbD4PrAZewgpo9AsgA3TY+xwE3DTduWpJf/zyxlHdcfEN+tO7nql4TFBENc1wVO1SDda2y275u+64+AbNj09Mu2/Q6Y/rdeZzVHV7VZ0PnADcpqonAcuA99i7eZ6J1YzRGdziRIoLel5dGON0i4GzReRJrDbeD7w8+WRAIjNkYJiGsELxBRJpU1UHgAH7+9PAG/26lgm9Z3DLZFSwgJ2u5RQpZoaBwS39IekvW9Lpkh0xUiGEyzY0F2GlQm5Bp7PG6KxxeIOhMt2JDroT8cDbdC3odCb0nsE9YQQoajmnGxzO0W/acwaXhJGrruWczsS7NNRCGLnqWsrpJgrKuhEzw8DgnnSvqV42xIbNeQpqhgsM7kmnkqzbnGeioIFds6Wczun67TMlncEl/akEqrAuwNkGLeZ0Ro1iqI2+EKRgLel0/SblscElYegvW8rpBo3u0lAjYQSdbSmny2TzdMaFWTM6wzbF0CRMhuILcNigxZwuR1+PkYAZ3NOb7CDRETMlXb1YEjDTnjO4R0QCjwrWek5n2nOGGkkHnKuutZxu2EjADLUTdCi+lnE6VWXISMAMdRD0TIOWcbqNo2OMTaiRgBlqxol/WQhICtYyTjc1MG5KOkNtpFNJJgrKhtGxQK7XQk5nUh4b6sN5ZoYCqmK2kNNZN6zPVC8NNeI8M0ENG7SO0xkJmKFOJqOCBTRs0DpOl80TE5jTbUo6Q20EnQq5hZwux9yeJPGYkYAZamPWjE46YhLYsIFvTiciXSJyr4g8KCIPi8gX7fW+ZGI1OekM9RKLCX0BBijys6TLAYer6t7AQuAYETkQnzKxDmbzZrjAUDfWAHmTt+nsrEJZe7HT/ig+ZWI1KY8NjRCkKsXv9MdxEVkBvALcAjyFD5lYVdVULw0NEaT+0teA/6o6ASwUkdnAb4E93B5bSybWPy0dIDdeYOMrzzMw8ErjhntEVDOeRtUuCM+20fV5Xtk0xrJly8rOx2yKTKylH+A84DP4kIn16cGs7rj4Br3mvjXTJdQMlKhmPI2qXarh2fa9O57SHRffoBs258tub4pMrCLSb5dwiMgM4EjgUXzIxDoZBcx0pBjqJMgARX626bYBlonISuBvwC2qegM+ZGIdMjnpDA0S5AC5b206VV0J7FNmveeZWAeN2NnQIJP5xwMIOtsSihTn7TS3x5R0hvro62mN6mVgZLI55nR30hlviX/HEAJzexLEJJjqZUs8pSYgkaFR4jFhbk9isqniJy3idCYgkaFxglKltIjTmZTHhsYxTlcDlu7SdKIYGiOoVMhN73S5CWUkP2Gql4aGCSoVctM73aacFTat3zidoUHSvUlGxyYYyY1Pv3MDNL3TbcxbTmdyGBgaJSgpWNM7nVPSmeqloVGCylXX/E6XN05n8AbnGRr0uV3XMk5n4l0aGsUJ9zE0Ykq6qmzMKb1dHSQ74mGbYmhyHO2u3z2YTe90m/Jqei4NntAZjzG7u9O06aZjU05Ne87gGUGoUpre6Tbm1QwXGDwjCFVK0zudKekMXhJE/Mumdrrc+ASbx81wgcE7ggjF19RON2TCNBg8pr83yXBunC1jE75do6mdLmMCEhk8JghVSms4nZlLZ/CIdAC56pra6WJLb+Oan32a7ZffFbYphhYhnUpy8OoVzH/nkbB0qS/XaGqn2/2Kr7H/i4/R99X/DtsUQ4uQ7k1y9p9/zuwV98F55/lyjaZ2up4lX+Ll3RcQv/iisE0xtAjzepPMuWQJ4286EC680Jdr+JpAxG9mvv0Y7k91MW/RorBNMbQIHfEYu5x4PJx4vG/XaOqSzmBoRvxMILKDiCwTkUfs9Mdn2evnisgtIvKE/XeOXzYYDFHEz5JuHPhPVV0AHAicISILgM8BS1V1V2CpvWwwtA1+pj9eq6r329+HsdJkbQccj5X2GDxMf2wwNAti5bjz+SIi84E7gL2A51TVyVsnwHpnueSY4kys+1199dVlz53NZkmlUv4Y3iBRtS2qdkF0bSu267DDDluuqvvXfbJGMkq6+QApYDnwL/byhpLt66c7x3SZWKNKVG2Lql2q0bWtKTKxAohIJ3At8AtVvc5e/bKIbGNv3waITpJwgyEA/Oy9FKwsq4+q6teLNl2PlfYYPEp/bDA0E34Ojh8CnAysEpEV9rpzgSXAr0XkNOBZ4H0+2mAwRA4/0x//BZAKm4/w67oGQ9QJpPeyUURkEKtULEcayARoTi1E1bao2gXRta3Yrh1Vtb/eEzWF01VDRO7TRrpvfSSqtkXVLoiubV7aZbSXBkPAGKczGAKmFZzuyrANqEJUbYuqXRBd2zyzq+nbdAZDs9EKJZ3B0FQ0tdOJyDEi8riIPCkigU4RqjJf8AIReUFEVtif44qOOce29XEROdpH21aLyCr7+vfZ68rOYxSLb9h2rRSRfX20a/ei+7JCRDaJyKfCuGci8kMReUVEHipaV/M9EpEP2fs/ISIfKnetV9GIcDPMDxAHngJ2BhLAg8CCAK+/DbCv/b0X+DuwALgA+HSZ/RfYNiaBnWzb4z7ZthpIl6z7KvA5+/vngK/Y348D/oglZDgQuCfA3+8lYMcw7hnwFmBf4KF67xEwF3ja/jvH/j5nums3c0n3RuBJVX1aVfPA1Vhz9QJBK88XrMTxwNWqmlPVZ4Ansf6HoKg0j/F44KdqcTcw2xGk+8wRwFOqWkn04Njmyz1T1TuAdWWuV8s9Ohq4RVXXqep64BbgmOmu3cxOtx2wpmj5eao/9L5hzxfcB7jHXvUJuxryw6JwFEHaq8DNIrLcnpcIME9V19rfXwLmhWBXMScAVxUth33PoPZ7VJd9zex0kUBEUljTlz6lqpuAK4BdgIXAWuB/QjDrUFXdFzgWK0zGW4o3qlU3Cq3bWkQSwDuB39ironDPtsLPe9TMTvcCsEPR8vb2usAoN19QVV9W1QlVLQDfY6o6FJi9qvqC/fcV4Le2DZXmMYZxH48F7lfVl207Q79nNrXeo7rsa2an+xuwq4jsZL85T8CaqxcIleYLlrSH/hlweseuB04QkaSI7ATsCtzrg109ItLrfAeOsm2oNI/xeuCDdg/dgcDGoiqWX5xIUdUy7HtWRK336CbgKBGZY1eJj7LXVSeIniofe8COw+o1fAr4fMDXPhSr+rESWGF/jgN+Bqyy118PbFN0zOdtWx8HjvXJrp2xevweBB527gvQhxV97QngVmCuvV6A/7XtWgXs7/N96wGGgFlF6wK/Z1hOvxYYw2qLnVbPPQJOxergeRL4sJtrG0WKwRAwzVy9NBiaEuN0BkPAGKczGALGOJ3BEDDG6QyGgDFOFxFEZLaInF60vK2IXOPTtTpF5H4/zm2YHuN00WE2MOl0qvqiqr7Hp2sdCtzp07kN02CcLjosAXax55N9TUTmO3O9ROQUEfmdPcdrtYh8QkTOFpEHRORuEZlr77eLiPzJFjr/WUT2qHCtY7CmqkwiInER+bGIPGTPxfuPaucUkXki8lsRedD+HOzbnWk1glRxmE9VhcR8tp7bNbkMnIKleOgF+oGNwMfsbZdiia3BUlPsan9/E3BbhWvdC3SXrNsPa5qKszy72jmBXxVdN06RwsR8qn+aOud4m7FMrXl7wyKyEfi9vX4V8AZ7tsPBwG8sWShgTf7cChHZDlinqptLNj0N7Cwi3wT+gDU1qNo5Dwc+CKCqE1gvAoMLjNM1D7mi74Wi5QLW7xjDSkO2cJrzHEMZUa6qrheRvbEmZn4MK8fEp1ye01ADpk0XHYaxqo91odZcvmdE5L0wGddj7zK7vqo9Z++fBmKqei3wBaxQFNXOuRT4uL0+LiKz6rW93TBOFxFUdQi40+7I+FqdpzkJOE1EnBkGW4WvEJE48DpVfazMsdsBA2JlWPo5cM405zwLOExEVmEl/VxQp81th5ll0EaIyKHAB1T1Y2Hb0s4YpzMYAsZULw2GgDFOZzAEjHE6gyFgjNMZDAFjnM5gCBjjdAZDwBinMxgC5v8B7xvUyg+WKzEAAAAASUVORK5CYII=\n",
        "metadata": {
         "needs_background": "light",
         "tags": []
        },
        "output_type": "display_data",
        "text/plain": "<Figure size 211.968x360 with 1 Axes>"
       }
      ]
     }
    },
    "c5be64294277465080c440372056c928": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "c5c2bf48c0bc45468b10dd906861729c": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "c78c40592afb491a99a5dfa4b3f5c8f1": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "FloatSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "FloatSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "FloatSliderView",
      "continuous_update": true,
      "description": "Temperature",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_dad066feb811486bb29c512755b7302e",
      "max": 70,
      "min": 55,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "0.1f",
      "step": 0.1,
      "style": "IPY_MODEL_4371d513ff684bd7938b9c31707436d7",
      "value": 64
     }
    },
    "cba45f6e566f416280afc4fcdc808692": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "cf9a26346571456881e12f4a442a46e5": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "d1663d93e42341278a6be526dd532b76": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "IntSliderModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "IntSliderModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntSliderView",
      "continuous_update": true,
      "description": "PCR Cycles",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_9122619ce93f462bbb52a7ebe0d954af",
      "max": 30,
      "min": 1,
      "orientation": "horizontal",
      "readout": true,
      "readout_format": "d",
      "step": 1,
      "style": "IPY_MODEL_6f4c32ce47774344b6d8ffa18a78166f",
      "value": 3
     }
    },
    "d430b208deb54f48b43d738050ffa9cd": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_612ba6f12f7142efa0d701fc896a7f76",
      "max": 120,
      "min": 20,
      "step": 1,
      "style": "IPY_MODEL_a9af4ee00c164def88cd3968d909b942",
      "value": 60
     }
    },
    "d9db3b4edeb949419bd2ae2f1c6cb170": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_4c3f1a3c854844e3b92a315e8d42e16e",
      "placeholder": "​",
      "style": "IPY_MODEL_fd41b4626e0d47c1aee3a6409dc4df63",
      "value": "Annealing"
     }
    },
    "da5eb9491f66409688973c010ac0c864": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "dad066feb811486bb29c512755b7302e": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "dedb204e564f4474837d6e174f94d719": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "SliderStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "SliderStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": "",
      "handle_color": null
     }
    },
    "e0aea54962294e45af5790c87034b0fd": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_6656167384d344418f402f22552fd779",
      "max": 120,
      "min": 30,
      "step": 1,
      "style": "IPY_MODEL_cf9a26346571456881e12f4a442a46e5",
      "value": 60
     }
    },
    "e57ae2c434c44516bbbff1b4f7447b39": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": "80px"
     }
    },
    "e5e3949463674e88a9f885d96b0cab81": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "e6c94812e41d41ebbb3fc25248b038e5": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "e973848151494e7da617039ed941960d": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_d9db3b4edeb949419bd2ae2f1c6cb170",
       "IPY_MODEL_7aa969143d8e46919d8a2924791515fa",
       "IPY_MODEL_d430b208deb54f48b43d738050ffa9cd"
      ],
      "layout": "IPY_MODEL_9b6b9577e6124b6fa8ebc059f2569e42"
     }
    },
    "e9886b9fd3df43489c7e404cecaf42c8": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "eacb9c40192444a5be734b67d3c48aa0": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "eb56b460a87f449eb0b8be05893b4a83": {
     "model_module": "@jupyter-widgets/output",
     "model_name": "OutputModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/output",
      "_model_module_version": "1.0.0",
      "_model_name": "OutputModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/output",
      "_view_module_version": "1.0.0",
      "_view_name": "OutputView",
      "layout": "IPY_MODEL_90b5a1506c6a4315b71dcb33ae2282e1",
      "msg_id": "",
      "outputs": [
       {
        "image/png": "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\n",
        "metadata": {
         "needs_background": "light",
         "tags": []
        },
        "output_type": "display_data",
        "text/plain": "<Figure size 1080x360 with 2 Axes>"
       }
      ]
     }
    },
    "ef971f8422594f069b9792976b89a25f": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "LabelModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "LabelModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "LabelView",
      "description": "",
      "description_tooltip": null,
      "layout": "IPY_MODEL_3181c5b32d7a47dda3973e0269135ef7",
      "placeholder": "​",
      "style": "IPY_MODEL_00ec856d54e74129afc3b144c42a2509",
      "value": "Extension"
     }
    },
    "f0091324a47f4dceb9e1a888d33b6e04": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    },
    "f4818089299346f19505570c38e100f4": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "BoundedIntTextModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "BoundedIntTextModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "IntTextView",
      "continuous_update": false,
      "description": "Duration",
      "description_tooltip": null,
      "disabled": false,
      "layout": "IPY_MODEL_c5be64294277465080c440372056c928",
      "max": 120,
      "min": 10,
      "step": 1,
      "style": "IPY_MODEL_3e4b4e50a7134173bc8733cae4bf4166",
      "value": 20
     }
    },
    "f8607f3d257c44b997c5e54a6cd2e08a": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "HBoxModel",
     "state": {
      "_dom_classes": [],
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "HBoxModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/controls",
      "_view_module_version": "1.5.0",
      "_view_name": "HBoxView",
      "box_style": "",
      "children": [
       "IPY_MODEL_109e276b736845ed9b6d16495dd2b4f0",
       "IPY_MODEL_c78c40592afb491a99a5dfa4b3f5c8f1",
       "IPY_MODEL_7d146eb78c5b4747956e25d04b09affa"
      ],
      "layout": "IPY_MODEL_130d454037b645db901e3bddf8f16877"
     }
    },
    "fd17a1e6b4254d49aa2dbb7a49fe77b5": {
     "model_module": "@jupyter-widgets/base",
     "model_name": "LayoutModel",
     "state": {
      "_model_module": "@jupyter-widgets/base",
      "_model_module_version": "1.2.0",
      "_model_name": "LayoutModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "LayoutView",
      "align_content": null,
      "align_items": null,
      "align_self": null,
      "border": null,
      "bottom": null,
      "display": null,
      "flex": null,
      "flex_flow": null,
      "grid_area": null,
      "grid_auto_columns": null,
      "grid_auto_flow": null,
      "grid_auto_rows": null,
      "grid_column": null,
      "grid_gap": null,
      "grid_row": null,
      "grid_template_areas": null,
      "grid_template_columns": null,
      "grid_template_rows": null,
      "height": null,
      "justify_content": null,
      "justify_items": null,
      "left": null,
      "margin": null,
      "max_height": null,
      "max_width": null,
      "min_height": null,
      "min_width": null,
      "object_fit": null,
      "object_position": null,
      "order": null,
      "overflow": null,
      "overflow_x": null,
      "overflow_y": null,
      "padding": null,
      "right": null,
      "top": null,
      "visibility": null,
      "width": null
     }
    },
    "fd41b4626e0d47c1aee3a6409dc4df63": {
     "model_module": "@jupyter-widgets/controls",
     "model_name": "DescriptionStyleModel",
     "state": {
      "_model_module": "@jupyter-widgets/controls",
      "_model_module_version": "1.5.0",
      "_model_name": "DescriptionStyleModel",
      "_view_count": null,
      "_view_module": "@jupyter-widgets/base",
      "_view_module_version": "1.2.0",
      "_view_name": "StyleView",
      "description_width": ""
     }
    }
   }
  }
 },
 "nbformat": 4,
 "nbformat_minor": 1
}